Time to name and shame
Biased opinions about HT*
Thanks to Ellen Grant for alerting me to this in PLOS Medicine. The background is that there is good evidence that post menopausal hormone therapy (HT) causes breast cancer, and does not protect against cardiovascular disease – it may even increase that as well. Overall it does more harm than good. Correct advice to women should be:
Avoid if possible. If you must take it for relief of hot flushes, take the lowest dose for the shortest time possible.
The manufacturers don’t like that, so they pay influential doctors in the hope that they will write biased articles downplaying the risks. It seems to be working. Articles promoting HT were 2.4 times (95% confidence interval 1.5-4.9) more likely to have authors with conflicts of interest than those without.
The dodgy authors were named and shamed. Here they are:
Leon Speroff. Oregon Health Sciences University
Thomas B. Clarkson. Wake Forest University School of Medicine, North Carolina
Peter Kenemans. Vrije Universiteit, Amsterdam
Rogerio A. Lobo. Columbia University Medical Center. New York.
David M. Herrington. Wake Forest Medical Center, North Carolina.
Marius J. van der Mooren.Vrije Universiteit, Amsterdam
Rowan T. Chlebowski. University of California, Los Angeles
Susan R. Davis. Monash University.
Big names all, and I doubt they’re the only ones. We’ll return to this subject.
*Hormone replacement therapy (HRT) changed to hormone therapy (HT) Jan 2016