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Wild swimming in the Trent gravel pits

November 30, 2020

Sand and gravel has been quarried along the Trent for hundreds of years. The two official swimming lakes, Colwick Park (click here) and the Notts County Sailing Club lake at Hoveringham (click here or here for details) will suit many. But organised wild swimming? Not me.

Some lakes are inaccessible, or too closely guarded by their owners, but a few are perfect for a discreet dip. For swimming spots on the river click here.

Hoveringham

Three lakes run alongside the railway line here. The smaller ones at either end are heavily  fished – no swimming. But the middle and largest, Railway Lake, is perfect. A sailing, canoeing & windsurfing club has put up all sorts of entry barriers, and their groundsman believes the whole lake is “no swimming”, so be discreet.

     

Enter by the path at Thurgaton station, but avoid the main footpath along the railway line. It’s over a mile before you can cross the ditch separating you from the lake.  Instead follow the permissive path signs, through an unlocked gate and along the north shore. The further you go, the more private it gets.

      

The best spots are where the trees give way to grass and reeds.

Lovely clean gravel beds. No weeds. Just me and the dragon flies.

Gunthorpe

The Gunthorpe lakes are all owned by angling clubs, who fish all year, and don’t like swimmers. I swam in Dollar Lake, the largest one adjacent to the river. If you walk in from the river bank on a quiet day, there no fences, and the fishermen tend to drive in from the opposite direction.

Bleasby

Bleasby Lake, at the end of Sycamore Lane, near the sawmill, is the only swimmable lake in Bleasby. There’s usually a few fishermen, but it’s rarely crowded, and they’ve never objected to me swimming. Loads of good access points. Weedy in parts.

Jubilee Ponds would be perfect, and they’re accessible on foot down Borrow Bread Lane, but sadly, “No swimming”.

         

Gibsmere lake is also private fishing only – “No swimming”.  But don’t despair. There’s a couple of good spots on the Trent at Hazleton (click here).

Newark/South Muskham

There are many flooded pits between Newark and South Muskham, mostly around the sugar factory. But they’re all fishing lakes, or inaccessible, or both.

North Muskham

North Muskham Lake Nature Reserve (click here) is “no swimming”.  But walk north (downstream) from The Muskham Ferry pub (click here), past the fenced-off Nature Reserve lake. The second lake is set back behind grassland and invisible from the path, but the third is adjacent to the path with easy access. An idyllic spot.

    

Cromwell

You can swim in the river (click here) but the local gravel pit is still being worked by Tarmac – definitely no swimming!

Jim Thornton

Women’s Work

October 26, 2020

Two poems by UA Fanthorpe

      

Degas painted dozens of “La Repasseuse” Woman Ironing pictures. The one Fanthorpe refers to (right above) is in the Walker Art Gallery in Liverpool. It’s the last in a series of three of this particular pose. The George Bernard Shaw quote is from the play Man & Superman.

Woman Ironing

I thought I knew what was coming when he said,
He wanted to do my likeness at the ironing.
I live in the city, people tell you things. Me looking at him,
It would be, across the ironing board, my hair and my eyes
In a good light, and something a bit off the shoulder

But it wasn’t. He rushed around drawing curtains
Made it hard to iron. O yes, I had to keep ironing.
He need to see the strength, he said. Kept on
About my dynamic right shoulder, then left it out
Though you can see where he ought to have put it.

Come on, what’s-your-name, he kept saying,
Show us that muscle power! That’s what I’m after.
I might’ve been an engine, not a person
No, I didn’t take to him, I’m used to rudeness,
But he was making such a sketch of me.

If someone’s paying you, it isn’t easy
To speak your mind. Still, Sir, I said,
I really don’t want to see my hair like that,
all scraped back, like a hot person’s hair,
And anyone can tell that under my arms I’m sweating.

Hair? Sweat? That’s how it is when you iron,
Says he. You’re not here to tell me what to do.
I’ll make you permanent, the way you look
When you’re ironing. O yes, he says, I’ll show you
The way you look when no one’s watching.

UA Fanthorpe

Mother Scrubbing the Floor

She had a dancer’s feet, elegant, witty.
We had our father’s, maverick spreaders of dirt.

Dirt from London, dirt from Kent
Mud, dust, grass, droppings, wetness, things,
Dirt barefaced, dirt stinking, dirt invisible.

Whatever it was, she was ready:
The rubber kneeler, clanking galvanised bucket,
The Lifebuoy, the hard hot water.

Let me! we’d say, meaning Hate to see you do this.
Too old. Too resentful. Besides, you’ll blame us
That you had to do it.

She never yielded. We couldn’t do it right,
Lacking her hatred of filth, her fine strong hands.

Don’t want you to do this, she said. Don’t want you to have to.
Just remember this: love isn’t sex.
But the dreary things you do for the people you love.
And ‘Home is the girl’s prison,
The woman’s workhouse.’ Not me; Shaw.

I do remember. I stand where she knelt.

UA Fanthorpe

Indirect effects of the Covid-19 pandemic on pregnancy

October 8, 2020

Primary sources

Ripe-tomato.org has been collecting primary scientific (click here) & newspaper reports (click here) of Covid-19 or SARS-CoV-2 infection in pregnancy since early in the pandemic (click here for our Covid-19 in pregnancy navigation page).

Here we (Jim Thornton, Keelin O’Donoghue and Kate Walker) collect primary scientific reports of the indirect effects of the pandemic on pregnancy.  As usual facts but no comments. For convenience we list papers in roughly reverse order, newest first. We will update regularly.

Update 2 August – papers 84 and 85 added

Paper 85 – reduced preterm births in Australia

From three maternity hospitals in Melbourne (click here or paper). Citation: Rolnik DL, Matheson A, Liu Y, Chu S, McGannon C, Mulcahy B, Malhotra A, Palmer KR, Hodges RJ, Mol BW. The impact of COVID-19 pandemic restrictions on pregnancy duration and outcomes in Melbourne, Australia. Ultrasound Obstet Gynecol. 2021 Jul 26. doi: 10.1002/uog.23743. Epub ahead of print. PMID: 34309931.

Paper 84 – Effect of first wave in Canada

Singleton hospital births between March to August 2020 (and same period 2015–2019) in all of Canada, excluding Quebec (click here or paper). Citation: Liu S, Dzakpasu S, Nelson C, Wei SQ, Little J, Scott H, Joseph KS. Pregnancy outcomes during the COVID-19 pandemic in Canada, March to August 2020. J Obstet Gynaecol Can. 2021 Jul 28:S1701-2163(21)00581-8. doi: 10.1016/j.jogc.2021.06.014. Epub ahead of print. PMID: 34332116.

Update 22 July – papers 80 to 83 added

Paper 83 – no effect on stillbirths in Germany

Stillbirth rates rose slightly from 2013 to 2019, but during the first wave in early 2020, were non-significantly lower than in 2019 (click here or paper). Citation: Kniffka MS, Nitsche N, Rau R, Kühn M. Stillbirths in Germany: On the rise, but no additional increases during the first COVID-19 lockdown. Int J Gynaecol Obstet. 2021 Jul 20. doi: 10.1002/ijgo.13832. Epub ahead of print. PMID: 34287881.

Paper 82 – excess maternal deaths in Mexico.

From goverment statistics (click here or paper). This is study 271 here. Citation: Lumbreras-Marquez MI, Campos-Zamora M, Seifert SM, Kim J, Lumbreras-Marquez J, Vazquez-Alaniz F, Fields KG, Farber MK. Excess Maternal Deaths Associated With Coronavirus Disease 2019 (COVID-19) in Mexico. Obstet Gynecol. 2020 Dec;136(6):1114-1116. doi: 10.1097/AOG.0000000000004140. PMID: 32909969.

Paper 81 – reduced hospital birth in India

From Jodpur (click here or paper). This is study 343 here. The authors are from All India Institute of Medical Sciences,
Jodhpur, which is the same instutue as the different authors of paper 37. Since the time periods overlap there may some patietn overlap. Citation: Goyal M, Singh P, Singh K, Shekhar S, Agrawal N, Misra S. The effect of the COVID-19 pandemic on maternal health due to delay in seeking health care: Experience from a tertiary center. Int J Gynaecol Obstet. 2021 Feb;152(2):231-235. doi: 10.1002/ijgo.13457. Epub 2020 Dec 21. PMID: 33128794.

Paper 80 – shortened post-partum stay during first wave

From New York (click here or paper). Citation: Bornstein E, Gulersen M, Husk G, Grunebaum A, Blitz MJ, Rafael TJ, Rochelson BL, Schwartz B, Nimaroff M, Chervenak FA. Early postpartum discharge during the COVID-19 pandemic. J Perinat Med. 2020 Nov 26;48(9):1008-1012. doi: 10.1515/jpm-2020-0337. PMID: 32845868.

Update 20 July – paper 79 added

Paper 79 – reduced miscarriage during first wave

From the Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, New York (click here or paper). Citation: Bortoletto P, Romanski PA, Stewart J, Rosenwaks Z, Pfeifer SM. Incidence of first trimester pregnancy loss in the infertile population during the first wave of the coronavirus disease 2019 pandemic in New York City. F S Rep. 2021 Apr 28;2(2):209-214. doi: 10.1016/j.xfre.2021.04.005. PMID: 34278356; PMCID: PMC8267398.

Update 18 July – paper 78 added

Paper 78 – fewer Caesarean and preterm births during lockdown in Iceland

National data (click here or paper). Citation: Einarsdóttir K, Swift EM, Zoega H. Changes in obstetric interventions and preterm birth during COVID-19: A nationwide study from Iceland. Acta Obstet Gynecol Scand. 2021 Jul 13. doi: 10.1111/aogs.14231. Epub ahead of print. PMID: 34255860.

Update 16 July – paper 46 citation updated. Paper 77 added

Paper 77 – lower ASQ scores for infants born during pandemic

According to this MedRxiv preprint, infants born during the pandemic had lower Ages & Stages Questionnaire scores than those born pre-pandemic (click here or paper). See also study 751 (click here). Citation: Lauren C. Shuffrey, Morgan R. Firestein, Margaret Kyle, Andrea Fields, Carmela Alcantara, Dima Amso, Judy Austin, Jennifer M. Bain, Jennifer Barbosa, Mary Bence, Catherine Bianco, Cristina Fernandez, Sylvie Goldman, Cynthia Gyamfi-Bannerman, Violet Hott, Yunzhe Hu, Maha Hussain, Pam Factor-Litvak, Maristella Lucchini, Arthur Mandel, Rachel Marsh, Danielle McBrian, Mirella Mourad, Rebecca Muhle, Kimberly Noble, Anna A. Penn, Cynthia Rodriguez, Ayesha Sania, Wendy G. Silver, Kally C. O Reilly, Melissa Stockwell, Nim Tottenham, Martha G. Welch, Noelia Zork, William P. Fifer, Catherine Monk, Dani Dumitriu. Birth during the COVID-19 pandemic, but not maternal SARS-CoV-2 infection during pregnancy, is associated with lower neurodevelopmental scores at 6-months medRxiv 2021.07.12.21260365; doi: https://doi.org/10.1101/2021.07.12.21260365

Update 29 June – paper 76 added

Paper 76 – delayed diagnosis of ectopic pregnancy in Israel

From Tel Aviv (click here or paper). Citation: Anteby M, Van Mil L, Michaan N, Laskov I, Grisaru D. Effects of the COVID-19 pandemic on timely care for extrauterine pregnancies: A retrospective analysis. Lancet Reg Health Eur. 2021 Mar;2:100026. doi: 10.1016/j.lanepe.2021.100026. Epub 2021 Jan 13. PMID: 34173625; PMCID: PMC7804379.

Update 6 June – paper 75 added

Paper 75 – increased thromboembolism during lockdown in Israel

In 2020 the rate of pregnancy-related thromboembolic events was significantly higher than in 2018 and 2019 at the Mount Scopus and Ein Kerem campuses of Hadassah-Hebrew University Medical Center in jerusalem (click here or paper). Citation: Gabrieli D, Cahen-Peretz A, Shimonovitz T, Marks-Garber K, Amsalem H, Kalish Y, Lavy Y, Walfisch A. Thromboembolic events in pregnant and puerperal women after COVID-19 lockdowns: A retrospective cohort study. Int J Gynaecol Obstet. 2021 Jun 2. doi: 10.1002/ijgo.13777. Epub ahead of print. PMID: 34077561.

Update 3 June – paper 74 added

Paper 74 – Reduced prematurity in France

Preamature births fell in single but not in multiple pregnancies (click here or paper). There was no alteration in stillbirths. Citation: Simon E, Cottenet J, Mariet A-S, Bechraoui-Quantin S, Rozenberg P, Gouyon J-B, Quantin C, Impact of the COVID-19 pandemic on preterm birth and stillbirth: a nationwide, population-based retrospective cohort study, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.05.015.

Update 29 May – paper 73 added

Paper 73 – emergency dept avoidance but no adverse effects in Canada

In Ontario, after an initial reduction, ED presentations for ectopic pregnancy quickly returned to expected levels. In contrast presentations for miscarriage showed sustained reductions but complications and mortality rates did not alter during the pandemic (click here or paper). Citation: Gomez D, Simpson AN, Sue-Chue-Lam C, de Mestral C, Dossa F, Nantais J, Wilton AS, Urbach D, Austin PC, Baxter NN. A population-based analysis of the impact of the COVID-19 pandemic on common abdominal and gynecological emergency department visits. CMAJ. 2021 May 25;193(21):E753-E760. doi: 10.1503/cmaj.202821. PMID: 34035055.

Update 27 May – paper 72 added

Paper 72 – the first wave in Ethiopia

Government health facilities in Bench Sheko, Sheka, Keffa, and West Omo zones in southern Ethiopia reported reduced antenatal, family planning and newborn immunization visits, and health facility births, and more teenage pregnancies, abortions, institutional stillbirths and neonatal deaths during March–June 2020 (click here or paper). Citation: Kassie A, Wale A, Yismaw W. Impact of Coronavirus Diseases-2019 (COVID-19) on Utilization and Outcome of Reproductive, Maternal, and Newborn Health Services at Governmental Health Facilities in South West Ethiopia, 2020: Comparative Cross-Sectional Study. Int J Womens Health. 2021 May 19;13:479-488. doi: 10.2147/IJWH.S309096. PMID: 34040456; PMCID: PMC8141395.

Update 17 May – papers 70 and 71 added

Paper 71 – more ruptured ectopic pregnancies in USA

From Newark, Delaware (click here or paper). Citation: Toma, Helen V. MD, MSPH; Bank, Tracy Caroline MD; Hoffman, Matthew K. MD, MPH Care for Women With Ectopic Pregnancies During the Coronavirus Disease 2019 (COVID-19) Pandemic, Obstetrics & Gynecology: May 06, 2021 – Volume Latest Articles – Issue – 10.1097/AOG.0000000000004392 doi: 10.1097/AOG.0000000000004392

Paper 70 – no change in preterm birth or stillbirth during first 6 months of pandemic

From Ontario, Canada (click here or paper). Citation: Simpson AN, Snelgrove JW, Sutradhar R, Everett K, Liu N, Baxter NN. Perinatal Outcomes During the COVID-19 Pandemic in Ontario, Canada. JAMA Netw Open. 2021;4(5):e2110104. doi:10.1001/jamanetworkopen.2021.10104

Update 16 May – paper 69 added

Paper 69 – More Caesareans in Brazil

From Dr. Miguel Riet Corrêa Jr., University Hospital of the Universidade Federal do Rio Grande (HU-FURG), in the state of Rio Grande do Sul (click here or paper). Citation: Manoela de Azevedo Bicho, Mayra Pacheco Fernandes, Luís Paulo Vidaletti, Juliana dos Santos Vaz. Cesarean section prevalence at a baby-friendly hospital in southern Brazil: current context in the face of COVID-19. medRxiv 2021.05.03.21256516; doi: https://doi.org/10.1101/2021.05.03.21256516

Update 15 May – paper 68 added

Paper 68 – fewer very preterm births during lockdown in Vienna

From the Viennese Danube Hospital (click here or study). Citation: Kirchengast S, Hartmann B. Pregnancy Outcome during the First COVID 19 Lockdown in Vienna, Austria. Int J Environ Res Public Health. 2021 Apr 5;18(7):3782. doi: 10.3390/ijerph18073782. PMID: 33916365; PMCID: PMC8038559.

Update 1 May – paper 67 added

Paper 67 – fewer antenatal attendances in Uganda

The authors of this MedRxiv preprint report many changes in maternity care and outcomes during the first wave at Kawempe National Referral Hospital in Kamapala (click here or paper). Citation: Jessica Burt, Joseph Ouma, Alexander Amone, Lorna Aol, Musa Sekikubo, Annettee Nakimuli, Eve Nakabembe, Robert Mboizi, Philippa Musoke, Mary Kyohere, Emily Namara, Asma Khalil, Kirsty Le Doare. Indirect Effects of COVID-19 on Maternal, Neonatal, Child, Sexual and Reproductive Health Services in Kampala, Uganda medRxiv 2021.04.23.21255940; doi: https://doi.org/10.1101/2021.04.23.21255940

Update 21 April – Paper 66 added

Paper 66 – increase in molar pregnancy in Israel

A doubling in the incidence of molar pregnancies at Galilee Medical Center, Nahariya, in January–October, 2020 (click here or paper). Citation: Aiob A, Naskovica K, Sharon A, Bornstein J. A possible association between hydatidiform mole and the COVID-19 pandemic: A retrospective cohort study. Gynecol Oncol. 2021 Mar 5:S0090-8258(21)00192-X. doi: 10.1016/j.ygyno.2021.02.035. Epub ahead of print. PMID: 33712273; PMCID: PMC7934616.

Update 11 April – papers 64 and 65 added

Paper 65 – fewer births and terminations in Italy

From the Institute for Maternal and Child Health, Trieste (click here or paper). Citation: Trombetta A, Travan L, Elefante P, Canton M, Rispoli F, Maso G, Barbi E, Risso FM. The first Italian COVID-19 lockdown reduced births and voluntary terminations by just under a fifth. Acta Paediatr. 2021 Mar 29. doi: 10.1111/apa.15862. Epub ahead of print. PMID: 33780031.

Paper 64 – reduced preterm birth rate in Saudi Arabia

From King Saud Medical City, Riyadh (click here or paper). Citation: Huseynova R, Bin Mahmoud L, Abdelrahim A, Al Hemaid M, Almuhaini MS, Jaganathan PP, Career H, Huseynov O. Prevalence of Preterm Birth Rate During COVID-19 Lockdown in a Tertiary Care Hospital, Riyadh. Cureus. 2021 Mar 1;13(3):e13634. doi: 10.7759/cureus.13634. PMID: 33816033; PMCID: PMC8011548.

Update 30 March – paper 63 added

Paper 63 – national changes in US

This MedRxiv preprint reports a fall in live births, preterm births and low birth weight babies in the United States during the pandemic (click here or paper). Citation: Alison Gemmill, Joan A. Casey, Ralph Catalano, Deborah Karasek, Tim Bruckner. Changes in live births, preterm birth, low birth weight, and cesarean deliveries in the United States during the SARS-CoV-2 pandemic. medRxiv 2021.03.20.21253990; doi: https://doi.org/10.1101/2021.03.20.21253990

Update 21 March – papers 61 and 62 added

Paper 62 – fewer OBGYN emergency hospital visits during first wave

Data from Kaiser Permanente Northern California, Oakland (click here or ). Citation: Abel, Mary Kathryn AB; Alavi, Mubarika X. MS; Tierney, Cassidy MD; Weintraub, Miranda Ritterman PhD, MPH; Avins, Andrew MD, MPH; Zaritsky, Eve MD Coronavirus Disease 2019 (COVID-19) and the Incidence of Obstetric and Gynecologic Emergency Department Visits in an Integrated Health Care System, Obstetrics & Gynecology: March 10, 2021 – Volume Latest Articles – Issue – 10.1097/AOG.0000000000004331 doi: 10.1097/AOG.0000000000004331 

Paper 61 – more abortion referrals and procedures during first wave.

From author affiliations the unnamed Northern California tertiary referral center may have been Dept. OBGYN, University of California, Davis, in Sacramento (click here or PgwZqt-PIIS0002937821001587). Citation: Creinin MD, Tougas H, Wilson M, Matulich MC, COVID-19 impact on abortion care at a Northern California tertiary family planning program American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.03.007. 

Update 20 March – paper 60 added

Paper 60 – no change in ethnic disparities in preterm birth in New York

Women who delivered from March 28 to July 31, 2020, in New York City, were compared with women who delivered from March 28 to July 31, 2019 (click here or janevic_2021_oi_210084_1615398911.43761). Citation: Janevic T, Glazer KB, Vieira L, Weber E, Stone J, Stern T, Bianco A, Wagner B, Dolan SM, Howell EA. Racial/Ethnic Disparities in Very Preterm Birth and Preterm Birth Before and During the COVID-19 Pandemic. JAMA Netw Open. 2021 Mar 1;4(3):e211816. doi: 10.1001/jamanetworkopen.2021.1816. PMID: 33729505.

Update 3rd March – papers 58 and 59 added. Additional data & citation paper 10. Paper 15 (abstract) and paper 22 (full paper) noted to report the same data.

Paper 59 – no change in preterm births in Massachussetts

Preterm birth rates, defined in various ways, did not alter significantyl in four Boston hospitals during the pandemic, compared with the previous year (click here or Preterm_Birth_During_the_Coronavirus_Disease_2019.2). Citation: Wood, Rachel MD; Sinnott, Colleen MD; Goldfarb, Ilona MD; Clapp, Mark MD, MPH; McElrath, Thomas MD, PhD; Little, Sarah MD, MPH Preterm Birth During the Coronavirus Disease 2019 (COVID-19) Pandemic in a Large Hospital System in the United States, Obstetrics & Gynecology: March 2021 – Volume 137 – Issue 3 – p 403-404. doi: 10.1097/AOG.0000000000004237 

Paper 58 – Increased stillbirths in India

Stillbirths were significantly increased during the pandemic in a large New Delhi hospital compared with the previous year (click here or ijgo.13564). Citation: Kumar, M., Puri, M., Yadav, R., Biswas, R., Singh, M., Chaudhary, V., Jaiswal, N. and Meena, D. (2021), Stillbirths and the COVID‐19 pandemic: Looking beyond SARS‐CoV‐2 infection. Int J Gynecol Obstet. https://doi.org/10.1002/ijgo.13564

Update 27 February – Papers 56 and 57 added

Paper 57 – Slightly fewer preterm births in Pittsburg

At University of Pittsburgh Medical Centres, Magee-Womens Hospital, births <37 weeks fell from 11.1% (1 Jan 2018 to 31 Jan 2020 pre-pandemic) to 10.1% (1 April 2020 to 27 October 2020 pandemic) (click here or 1-s2.0-S2589933321000252-main). Citation: Lara Lemon, Robert P. Edwards, Hyagriv N. Simhan. What is driving the decreased incidence of preterm birth during the COVID-19 pandemic? American Journal of Obstetrics & Gynecology MFM (2021), doi: https://doi.org/10.1016/j.ajogmf.2021.100330&nbsp;

Paper 56 – Effect of lockdown in Beijing, China

No major effects seen (click here or e047900.full). Citation: Du M, Yang J, Han N, et alAssociation between the COVID-19 pandemic and the risk for adverse pregnancy outcomes: a cohort studyBMJ Open 2021;11:e047900. doi: 10.1136/bmjopen-2020-047900

Update 25 February – paper 55 added

Paper 55 – HSIB first wave maternal death report

The UK Healthcare Safety Investigation Branch (HSIB) reviewed 20 maternal deaths (19 included in review) that occurred between 1 March and and 31 May 2020 (the first peak of the COVID-19 pandemic in England) (click here or HSIB_Maternal_Death_Report_V13). Citation: National Learning Report. Maternal death: learning from maternal death investigations during the first wave of the COVID-19 pandemic. Independent report by the Healthcare Safety Investigation Branch I2020/017. February 2021. 

Update 21 February – paper 54 added

Paper 54 – Delayed diagnosis of ectopic pregnancy in Israel

From Shaare Zedek Medical Center, Jerusalem (click here or ijgo.13647). Citation: Barg M, Rotem R, Mor P, Rottenstreich M, Fayez K, Grisaru-Granovsky S, Armon S. Delayed presentation of ectopic pregnancy during the COVID-19 pandemic: A retrospective study of a collateral effect. Int J Gynaecol Obstet. 2021 Feb 18. doi: 10.1002/ijgo.13647. Epub ahead of print. PMID: 33599285.

Update 13 February – paper 53 added

Paper 53 – no effect of pandemic on assisted reproduction outcomes in Italy

From Lombardy (click here or LeviSetti preprint 2021). Citation: Paolo Emanuele Levi-Setti, Federico Cirillo, Valentina Immediata et al. First Trimester Pregnancy Outcomes in a Large&nbsp;ART Center From the Lombardy County (Italy) During the Peak COVID-19 Pandemic., 08 February 2021, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-152522/v1]

Update 1 February – paper 52 added

Paper 52 – first wave hospital births in Israel

Poster presented at the Society of Materno-Fetal Medicine 2021 conference (SMFM 2021) . Fewer hospital births, and higher induction and Caesarean rates during the first wave at Shaare Zedek Medical Center in Jerusalem. Citation to follow.

Update 13 January – paper 51 added

Paper 51 – no association with preterm birth or stillbirth in Sweden

In this national registry study there was no increase in preterm births, or in stillbirths, over the period 1 April through 31 May 2020, compared with the same period over the previous five years (click here or m20-6367). Citation: Pasternak B, Neovius M, Söderling J, Ahlberg M, Norman M, Ludvigsson JF, Stephansson O. Preterm Birth and Stillbirth During the COVID-19 Pandemic in Sweden: A Nationwide Cohort Study. Ann Intern Med. 2021 Jan 12. doi: 10.7326/M20-6367. Epub ahead of print. PMID: 33428442.

Update 9 January – paper 50 added

Paper 50 – fewer & later pregnancy terminations in Texas

The effect of an executive order between March 22 and April 21, to postpone surgery that was not medically necessary, and which was interpreted by some as including abortion, is described (click here or jama_white_2021_ld_200123_1609269106.91809). Citation: White K, Kumar B, Goyal V, Wallace R, Roberts SCM, Grossman D. Changes in Abortion in Texas Following an Executive Order Ban During the Coronavirus Pandemic. JAMA. Published online January 04, 2021. doi:10.1001/jama.2020.24096

Update 2 January – paper 49 added

Paper 49 – more ruptured ectopics during first wave

The ratio of ruptured to unruptured ectopic pregnancies rose between March 15th and May 17th 2020 at Lenox Hill Hospital, New York (click here or ijcp.13925). Citation: Werner, S, Katz, A. Change in ectopic pregnancy presentations during the covid‐19 pandemic. Int J Clin Pract. 2020; 00:e13925. https://doi.org/10.1111/ijcp.13925

Update 23 December – Paper 48 added

Paper 48 – No major adverse effect of lockdown in Botswana

No increase in adverse perinatal outcomes during or after lockdown in Botswana. Rather, a modest reduction, driven primarily by reduced preterm birth and growth restriction (click here or caniglia AJOG 2020 (002)). Time period of lockdown validated against Facebook geolocation data. Citation: CANIGLIA EC, MAGOSI LE, ZASH R, DISEKO M, MAYONDI G, MABUTA J, POWIS K, DRYDEN-PETERSON S, MOSEPELE M, LUCKETT R, MAKHEMA J, MMALANE M, LOCKMAN S, SHAPIRO R, Modest reduction in adverse birth outcomes following the COVID-19 lockdown, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2020.12.1198.

Update 19 December – papers 46 and 47 added

Paper 47 – Antenatal care during lockdown in Ethiopia

Pregnant women attending ANC services at public hospitals in Northeast Ethiopia between February 2 & August 30, 2020 (click here or ijwh-287534-antenatal-care-service-utilization-of-pregnant-women-attendi). No control group. Citation: Tadesse E. Antenatal Care Service Utilization of Pregnant Women Attending Antenatal Care in Public Hospitals During the COVID-19 Pandemic Period. Int J Womens Health. 2020;12:1181-1188. Published 2020 Dec 8. doi:10.2147/IJWH.S287534

Paper 46 – Fewer planned moderately preterm births in an Australian hospital

During the 2020 lockdown, rates of planned (iatrogenic) moderately preterm birth fell in the Mater Mothers’ Hospital, South Brisbane, Queensland (click here or 2020.11.24.20237529.full). Outcomes not reported. Citation: Linda A. Gallo, Tania F. Gallo, Danielle J. Borg, Karen M. Moritz, Vicki L. Clifton, Sailesh Kumar. Preterm birth rates in a large tertiary Australian maternity centre during COVID-19 mitigation measures medRxiv 2020.11.24.20237529; doi: https://doi.org/10.1101/2020.11.24.20237529 Update 16 July – peer reviewed version published (click here or paper). Citation: Gallo LA, Gallo TF, Borg DJ, Moritz KM, Clifton VL, Kumar S. A decline in planned, but not spontaneous, preterm birth rates in a large Australian tertiary maternity centre during COVID-19 mitigation measures. Aust N Z J Obstet Gynaecol. 2021 Jul 12. doi: 10.1111/ajo.13406. Epub ahead of print. PMID: 34254286.

Update 15 December – paper 45 added

Paper 45 – fewer visits during lockdown in Nanjing, China

Hospital visits for pregnancy care fell during lockdown in Zhongda Hospital, Southeast University, Nanjing, Jiangsu Province, China grid.452290.8 (click here or 10.1177_0300060520939337). There were no reported harms. Citation: Gu XX, Chen K, Yu H, Liang GY, Chen H, Shen Y. How to prevent in-hospital COVID-19 infection and reassure women about the safety of pregnancy: Experience from an obstetric center in China. J Int Med Res. 2020;48(7):300060520939337. doi:10.1177/0300060520939337

Update 14 December – paper 44 added

Paper 44 – increased stillbirths during 1st wave in Israel

Stillbirth were increased in the period  February 21 to April 30 2020, compared with the corresponding periods for 2017 to 2019 in Shamir Medical Center, Zerifin, Israel (click here or s-0040-1721515). Citation: Matan Mor, Nadav Kugler, Eric Jauniaux, Moshe Betser, Yifat Wiener, Howard Cuckle, Ron Maymon. Impact of the COVID-19 Pandemic on Excess Perinatal Mortality and Morbidity in Israel. Am J Perinatol DOI: 10.1055/s-0040-1721515

Update 10th December – paper 43 added

Paper 43 – rise in the rate of ruptured ectopic pregnancies

In Sant’Orsola-Malpighi University Hospital in Bologna, Italy, the rate of ruptured ectopic pregnancies normally 52/201 (26%) rose to 6/9 (66%) during the first lockdown period (click here or uog.22126). Citation: Casadio, P., Youssef, A., Arena, A., Gamal, N., Pilu, G. and Seracchioli, R. (2020), Increased rate of ruptured ectopic pregnancy in COVID‐19 pandemic: analysis from the North of Italy. Ultrasound Obstet Gynecol, 56: 289-289. https://doi.org/10.1002/uog.22126

Update 8th December – papers 41 and 42 added

Paper 42 – no significant alteration in stillbirths during first wave in England

There was no significant alteration in stillbirths overall, or in any region of the UK during the first wave (click here or jama_stowe_2020_ld_200113_1607178377.6775) Citation: Stowe J, Smith H, Thurland K, Ramsay ME, Andrews N, Ladhani SN. Stillbirths During the COVID-19 Pandemic in England, April-June 2020. JAMA. Published online December 07, 2020. doi:10.1001/jama.2020.21369

Paper 41- no significant alteration in preterm births or in stillbirths during first wave in Philadelphia

There were no significant alterations in the patterns, or overall rates, of preterm births or stillbirths during the first wave, in two Philadelphia hospitals (click here or jama_handley_2020_ld_200111_1607178374.44311 (1)). Citation: Handley SC, Mullin AM, Elovitz MA, et al. Changes in Preterm Birth Phenotypes and Stillbirth at 2 Philadelphia Hospitals During the SARS-CoV-2 Pandemic, March-June 2020. JAMA. Published online December 07, 2020. doi:10.1001/jama.2020.20991

Update 7th December – paper 40 added

Paper 40 – 16 maternal deaths in Indonesia

From March to May 2020, 16 pregnant or postnatal women died in West Sumatra (click here or 10.1080@0167482X.2020.1779216). It is not reported whether these were caused by Covid-19 or other diseases. Citation: Mijke Lambregtse-van den Berg, Julie Quinlivan. (2020) Identifying pregnant women at risk of developing COVID-19 related mental health problems – a call for enhanced psychoeducation and social support. Journal of Psychosomatic Obstetrics & Gynecology 41:4, pages 249-250.

Update 5th December – papers 38 and 39 added

Paper 39 – no major obstetric effects of lockdown in Wuhan, China

The Maternal and Child Hospital of Hubei Province (which I believe is part of Huazhong University of Science and Technology Hospital grid.488485.d) observed no major effects of lockdown compared with the previous year (click here or journal.pone.0237420). The Caesarean rate, for example, rose from 47% to 48%. Citation: Li M, Yin H, Jin Z, Zhang H, Leng B, Luo Y, Zhao Y. Impact of Wuhan lockdown on the indications of cesarean delivery and newborn weights during the epidemic period of COVID-19. PLoS One. 2020 Aug 13;15(8):e0237420. doi: 10.1371/journal.pone.0237420. PMID: 32790709; PMCID: PMC7425855.

Paper 38 – reduced prenatal diagnosis procedures Trabzon, Turkey

Between 11 March and 30 June 2020 prenatal dignosis procedures reduced by about one third at Karadeniz Perinatology Clinic, compared with the same period in the previous year (click here or Effect of COVID 19 pandemic process on prenatal diagnostic procedures (1)). Citation: Mirac Ozalp, Omer Demir, Hümeyra Akbas, Ecem Kaya, Cemre Celik & Mehmet Armagan Osmanagaoglu (2020) Effect of COVID-19 pandemic process on prenatal diagnostic procedures, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1815190

Update 3rd December – paper 37 added

Paper 37 – Reduced hospitalisation & increased maternal & perinatal mortality in Jodhpur, India

Reduced hospitlisation and emergency referrals after lockdown, coincided with increased in-hospital maternal mortality, and late intrauterine fetal death and stillbirth in a group of four hospitals associated with Dr S N Medical College, Jodhpur, India (click here or PIIS2214109X20303193). Citation: Kumari V, Mehta K, Choudhary R. COVID-19 outbreak and decreased hospitalisation of pregnant women in labour. Lancet Glob Health. 2020 Sep;8(9):e1116-e1117. doi: 10.1016/S2214-109X(20)30319-3. Epub 2020 Jul 14. PMID: 32679037.

Update 2nd December – papers 35 and 36 added

Paper 36 – freebirth due to fear of Covid in Iran

A woman from Dezful, Khuzestan province in Iran had a normal birth alone at home because she was fearful of contracting Covid-19 in hospital (click here or IJPS-15-366). Both mother and baby were fine. Citation: Nosratabadi M, Sarabi N, Masoudiyekta L. A Case Report of Vaginal Delivery at Home due to Fear of Covid-19. Iran J Psychiatry. 2020;15(4):366-369. doi:10.18502/ijps.v15i4.4306

Paper 35 – delayed presentation in labour in Sao Paolo, Brazil

In São Paulo Hospital betwee March 11 and June 11, more women presented in advanced labour (click here or ijgo.13357). Citation: Sun, S.Y., Guazzelli, C.A.F., de Morais, L.R., Dittmer, F.P., Augusto, M.N., Soares, A.C., Coutinho da Silva, P.M., Abuchaim, E.d.S.V. and Mattar, R. (2020), Effect of delayed obstetric labor care during the COVID‐19 pandemic on perinatal outcomes. Int J Gynecol Obstet, 151: 287-289. https://doi.org/10.1002/ijgo.13357

Update 1st December – papers 32 to 34 added

Paper 34 – reduced risk of post partum depression during lockdown

Rates of raised EPDS scores were reduced during lockdown among women cared for at Soroka University Medical Center, Negev, Israel (click here or Pariente2020_Article_RiskForProbablePost-partumDepr). Citation: Pariente, G., Wissotzky Broder, O., Sheiner, E. et al. Risk for probable post-partum depression among women during the COVID-19 pandemic. Arch Womens Ment Health (2020). https://doi.org/10.1007/s00737-020-01075-3

Paper 33 – breast feeding during lockdown in Belgium

Reported behaviour of a self-selected sample (click here or ijerph-17-06766). Most women reported continuing breast feeding for longer during lockdown. Citation: Ceulemans, M.; Verbakel, J.Y.; Van Calsteren, K.; Eerdekens, A.; Allegaert, K.; Foulon, V. SARS-CoV-2 Infections and Impact of the COVID-19 Pandemic in Pregnancy and Breastfeeding: Results from an Observational Study in Primary Care in Belgium. Int. J. Environ. Res. Public Health 2020, 17, 6766.

Paper 32 – sexual behaviour during lockdown in China

Reported behaviour of a self-selected sample (click here or pdf (1)). Citation. Li G, Tang D, Song B, Wang C, Qunshan S, Xu C, Geng H, Wu H, He X, Cao Y. Impact of the COVID-19 Pandemic on Partner Relationships and Sexual and Reproductive Health: Cross-Sectional, Online Survey Study. J Med Internet Res. 2020 Aug 6;22(8):e20961. doi: 10.2196/20961. PMID: 32716895; PMCID: PMC7419154.

Update 27 November – paper 31 added

Paper 31 – effect of lockdown in Karnataka, India

The self-reported effects of lockdown of 290/315 pregnant women attending Shri B.M. Patil Medical College, Hospital and Research Center, Vijayapura, Karnataka, India, between 21/05/2020 & 08/06/2020 (click here or pmr-12-03-3). Citation: Dr. Rajasri G. Yaliwal, Dr. Aruna M.Biradar, Dr. Shreedevi S. Kori, Dr. Subhashchandra, R. Mudanur, Dr. Shivakumar U. Pujeri, Dr. Shailaja R. Bidri, Dr. Neelamma G. Patil. CHALLENGES OF PREGNANCY DURING THE COVID19 PANDEMIC AND LOCKDOWN –A CROSS-SECTIONAL STUDY. Pravara Med Rev; September 2020, 12(03) , 23-30 DOI: 10.36848/PMR/2020/13100.51291

Update 26 November – papers 29 and 30 added

Paper 30 – more women not receiving antenatal care in Jordan

The self-reported rate of women not receiving antenatal care in this online survey of self-selected members of women’s and motherhood groups in Jordan, rose from a recalled 38/944 (4%) before lockdown to 562 (60%) during lockdown (click here or ijwh-280342-pregnancy-during-covid-19-outbreak-the-impact-of-lockdown-i). Citation: Muhaidat N, Fram K, Thekrallah F, Qatawneh A, Al-Btoush A. Pregnancy During COVID-19 Outbreak: The Impact of Lockdown in a Middle-Income Country on Antenatal Healthcare and Wellbeing. Int J Womens Health. 2020;12:1065-1073 https://doi.org/10.2147/IJWH.S280342

Paper 29 – couples delaying conception in Shanghai, China

Of 447 couples who had been recorded before the pandemic as planning to conceive a pregnancy, 151 (34%) stated that they had altered their plans, presumably in the direction of cancelling or delaying trying for a baby (click here or ijgo.13366). Citation: Zhu, C., Wu, J., Liang, Y., Yan, L., He, C., Chen, L. and Zhang, J. (2020), Fertility intentions among couples in Shanghai under COVID‐19: A cross‐sectional study. Int. J. Gynecol. Obstet., 151: 399-406. https://doi.org/10.1002/ijgo.13366

Update 24th November – paper 28 added

Paper 28 – fewer & later attendances in pregnancy during first wave in Israel

Fewer pregnant women attended the emergency department during the first wave compared with the same period in the previous year, and those that did attended at later gestations or at more advanaced stages of labour. Hower, no differences were seen in outcomes (click here or Changes in the obstetrical emergency department profile during the COVID 19 pandemic). From author affiliations this was probably Carmel Medical Center, Haifa, Israel. Citation: Nir Kugelman, Ofer Lavie, Wisam Assaf, Nadav Cohen, Lena Sagi-Dain, Mordehai Bardicef, Reuven Kedar, Amit Damti & Yakir Segev (2020) Changes in the obstetrical emergency department profile during the COVID-19 pandemic, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1847072

Update 23rd November – paper 27 added

Paper 27 – cancelled clinic appointments in Iran

57/103 pregnant or post-partum women reported cancelling clinic appointments for themselves or their child during lockdown (click here or ijerph-17-08272). Participants were patients in the Department of Gynecology and Midwifery of the Arak University of Medical Sciences, Arak, Iran. Citation: Shayganfard, M.; Mahdavi, F.; Haghighi, M.; Sadeghi Bahmani, D.; Brand, S. Health Anxiety Predicts Postponing or Cancelling Routine Medical Health Care Appointments among Women in Perinatal Stage during the Covid-19 Lockdown. Int. J. Environ. Res. Public Health 2020, 17, 8272.

Update 20 November – paper 26 added

Paper 26 – no alteration in miscarriage rate after embryo transfer in New York

The authors of this conference abstract report that early pregnancy loss rates did not alter during the first wave of the SARS-CoV-2 pandemic (click here or PIIS0015028220323165). Citation: Flisser, Eric et al. PREGNANCY LOSS RATES AFTER SINGLE, EUPLOID FROZEN-THAWED EMBRYO TRANSFER IN THE COVID-19 ERA. Fertility and Sterility, Volume 114, Issue 3, e561 – e562

Update 14 November – paper 25 added

Paper 25 – more stillbirths & fewer late preterm births in Rome, Italy

Using the Lazio region hospital discharge database, the authors report fewer 32-36w births, & more stillbirths in March to May 2020, compared with the same period 2019 (click here or archdischild-2020-320682.full). Citation: De Curtis M, Villani L, Polo A. Arch Dis Child Fetal Neonatal Ed Epub ahead of print: doi:10.1136/archdischild-2020-320682 Accepted 21 October 2020 Arch Dis Child Fetal Neonatal Ed 2020;0:F1. doi:10.1136/fetalneonatal-2020-320682

Update 12 November – papers 22 to 24 added

Paper 24 – hospital births and postnatal depression scores in Hong Kong

Queen Mary Hospital, Pokfulam, Hong Kong observed a fall in hospital births and raised rates of Edinburgh postnatal depression scores over 10 during lockdown (click here or hkmj208774). Citation: PW Hui, Grace Ma, Mimi TY Seto, KW Cheung. Effect of COVID-19 on delivery plans and postnatal depression scores of pregnant women. Hong Kong Med J 2020;26:Epub 5 Nov 2020 https://doi.org/10.12809/hkmj208774

Paper 23 – stress during lockdown in Cork, Ireland

This survey reported no major differences in a range of self-reported psychological or behavioural outcomes during lockdown (click here or 1-s2.0-S187151922030367X-main). Citation: Karen Matvienko-Sikar, Johanna Pope, Avril Cremin, Hayley Carr, Sara Leitao, Ellinor K. Olander, Sarah Meaney. Differences in levels of stress, social support, health behaviours, and stress-reduction strategies for women pregnant before and during the COVID-19 pandemic, and based on phases of pandemic restrictions, in Ireland. Women and Birth. 2020,ISSN 1871-5192, https://doi.org/10.1016/j.wombi.2020.10.010. (http://www.sciencedirect.com/science/article/pii/S187151922030367X)

Paper 22 – lockdown did not affect miscarriage rates in Montreal, Canada

There was no difference in miscarriage/non-viable pregnancy rates in this Montreal fertility unit, between the period of the first wave, and an equivalent period in 2019 (click here or Rotshenker-Olshinka2020_Article_COVID-19PandemicEffectOnEarlyP). Citation: Rotshenker-Olshinka, K., Volodarsky-Perel, A., Steiner, N. et al. COVID-19 pandemic effect on early pregnancy: are miscarriage rates altered, in asymptomatic women?. Arch Gynecol Obstet (2020). https://doi.org/10.1007/s00404-020-05848-0 3 March update. This is the full report of paper 15 (abstract)

Update 10th November – paper 21 added

Paper 21 – shorter postnatal stay during pandemic in Los Angles

Women and babies who delivered in March and April 2020 at Cedars-Sinai Medical Center, Los Angeles, California, USA, had significantly reduced postpartum stays than those in prepandemic periods (click here or Greene AJOG MFM-main). No adverse effects were reported. Citation: Greene NH, Kilpatrick SJ, Wong MS, et al. Impact of labor and delivery unit policy modifications on maternal and neonatal outcomes during the coronavirus disease 2019 pandemic. Am J Obstet Gynecol MFM 2020;2:100234. https://doi.org/10.1016/j.ajogmf.2020.100234

Update 9th November – papers 19 and 20 added

Paper 20 – halving of emergency admissions during the pandemic in Bologna, Italy

In March 2020, the middle of the COVID-19 pandemic, emegency room attendances halved compared with March 2019 in S.Orsola-Malpighi University Hospital of Bologna (click here or Salsi AJOG MFM). Citation: Ginevra Salsi, Anna Seidenari, Josefina Diglio, Federica Bellussi, Gianluigi Pilu, Federica Bellussi. Obstetrics and gynecology emergency services during the coronavirus disease 2019 pandemic. American Journal of Obstetrics & Gynecology MFM, Volume 2, Issue 4, Supplement, 2020, 100214, ISSN 2589-9333, https://doi.org/10.1016/j.ajogmf.2020.100214. (http://www.sciencedirect.com/science/article/pii/S2589933320301828)

Paper 19 – halving of admissions & births during the pandemic in Jodhpur, India

Over the period of the pandemic, hospital admissions in pregnancy, and hospital births halved in the All India Institute of Medical Sciences, Jodhpur, a tertiary referral hospital (click here or ijgo.13457). 32 pregnant women with Covid-19 were included, so this paper is also included as study 343 here. Citation: Goyal, M., Singh, P., Singh, K., Shekhar, S., Agrawal, N. and Misra, S. (2020), The effect of the COVID‐19 pandemic on maternal health due to delay in seeking health care: Experience from a tertiary center. International Journal of Gynecology & Obstetrics. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13457

Update 31st October – paper 18 added

Paper 18 – no effect on preterm births in California

No effect on preterm births over the pandemic first wave in California, apart from a small “increase” in births between 28 and 32 weeks (click here or Main AJOG 21 oct 2020 (1)). Citation: Main EK, Chang S-C, Carpenter AM, Wise PH, Stevenson DK, Shaw GM, Gould JB, Preterm birth rates for racial and ethnic groups during the COVID-19 pandemic in California, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.10.033.

Update 24 October – papers 16 and 17 added

Paper 17 – reduced general anaesthesia for Caesarean during lockdown, UK

Six hospitals observed a fall in Caesarean general anaesthesia rates from 7.7 to 3.7% during the pandemic (click here or ). Citation; Bhatia K, Columb M, Bewlay A, Eccles J, Hulgur M, Jayan N, Lie J, Verma D, Parikh R. The effect of COVID-19 on general anaesthesia rates for caesarean section. A cross sectional analysis of six hospitals in the north-west of England. Anaesthesia. 2020 Oct 18. doi: 10.1111/anae.15313. Epub ahead of print. PMID: 33073371.

Paper 16 – reduced preterm birth in a Philadelphia hospital

In Thomas Jefferson University Hospital preterm birth fell from 13% in March 1-July 31 2019, to 10% in March 1-July 31 2020 (click here or berghella AJOGMFM). Citation: Berghella V, Burd J, Anderson K, Boelig R, Roman A, Decreased incidence of preterm birth during COVID-19 pandemic, American Journal of Obstetrics & Gynecology MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100258.

Update 20 October – papers 13 to 15 added

Paper 15  – miscarriage before and during lockdown in Montreal, Canada

No change (click here or main (4)) Citation: Olshinka KR, Volodarsky-Perel A, Steiner N, Rubenfeld ES, Dahan MH. COVID-19 PANDEMIC EFFECT ON EARLY PREGNANCY – ARE MISCARRIAGE RATES ALTERED, IN ASYMPTOMATIC WOMEN?. Fertil Steril. 2020;114(3):e525-e526. doi:10.1016/j.fertnstert.2020.09.036 March 3rd update. The full version of this abstract is reported in paper 22.

Paper 14 – diabetes control during lockdown in Lille, France

It deteriorated (click here or main (3)). Citation: Ghesquière L, Garabedian C, Drumez E, et al. Effects of COVID-19 pandemic lockdown on gestational diabetes mellitus: A retrospective study [published online ahead of print, 2020 Oct 15]. Diabetes Metab. 2020;doi:10.1016/j.diabet.2020.09.008

Paper 13 – the Covid-19 New Mum survey

Self-selected and self-reported UK maternal birth experiences before and after lockdown (click here or main (2)). Citation: A. Vazquez-Vazquez, Appetite, https://doi.org/10.1016/j.appet.2020.104985

Update 18 October – papers 10 to 12 added

Paper 12 – reduced preterm birth in The Netherlands

National study based on dried blood spot screening programme (click here or PIIS2468266720302231). Citation: Been, Jasper V et al. Impact of COVID-19 mitigation measures on the incidence of preterm birth: a national quasi-experimental study. The Lancet Public Health, Volume 0, Issue 0. https://doi.org/10.1016/S2468-2667(20)30223-1

Paper 11 – reduced preterm births in Dublin, Ireland

There was a small reduction in preterm birth, but no other effects, between 1st January & 31st July 2020 compared to the same period in 2019 in the Coombe Women & Infants University Hospital (click here or PIIS0301211520306539). Citation: McDonnell S, McNamee E, Lindow SW, O’Connell MP, The impact of the Covid-19 pandemic on maternity services: a review of maternal and neonatal outcomes before, during and after the pandemic, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.10.023

Paper 10 – reduced preterm births in Israel (update 3 March)

This preprint consists only of results tables (click here or PIIS0002937820311911 (1)). The corresponding author is from Chaim Sheba Medical Center, Israel. Citation: Meyer R, Friedrich L, Maixner N, Bart Y, Tsur A, Yinon Y, Levin G, A marked decrease in Preterm Deliveries during the COVID-19 Pandemic, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.10.017. Update 3 March. This paper (click here or 244117) with overlapping authorship, also reports the effect of lockdown in the same hospital. Citation:  Meyer R, Levin G, Hendin N, Katorza E. Impact of the COVID-19 Outbreak on Routine Obstetrical Management. Isr Med Assoc J. 2020 Aug;22(8):483-488. PMID: 33236580.

Update 12 October – papers 8 and 9 added

Paper 9 – effect of lockdown in one hospital in Israel

Various pregnancy complications  over March–April 2020 (the peak COVID-19 outbreak) in one large hospital, were compared with March–April 2019 in the same hospital (click here or 231152 (002)). From author affiliations the hospital was probably Rambam Health Care Campus in Haifa. Citation: Justman N, Shahak G, Gutzeit O, Ben Zvi D, Ginsberg Y, Solt I, Vitner D, Beloosesky R, Weiner Z, Zipori Y. Lockdown with a Price: The impact of the COVID-19 Pandemic on Prenatal Care and Perinatal Outcomes in a Tertiary Care Center. Isr Med Assoc J. 2020 Sep;9(22):467-471. PMID: 32954690.

Paper 8 – effect of lockdown in one hospital in Japan

The rates of women hospitalised for some pregnancy complications in Keio University Hospital between April 1st and June 30th, 2020, were compared with the same period 2017-19 (click here or jog.14518). No substantive outcomes reported. Citation: Kasuga, Y., Tanaka, M. and Ochiai, D. (2020), Preterm delivery and hypertensive disorder of pregnancy were reduced during the COVID‐19 pandemic: A single hospital‐based study. J. Obstet. Gynaecol. Res.. doi:10.1111/jog.14518

Update 9 October – papers 6 and 7 added

Paper 7 – reduced admission to emergency OBGYN during first wave in Milan, Italy

Between February 24th & May 31st 2020 emergency OBGYN admissions decreased by 35% at Clinica Mangiagalli, the largest maternity clinic in Milan, compared with the corresponding period in 2019   (click here or 1-s2.0-S0301211520305777-main). Five fetal deaths were seen in the emergency clinic in the pandemic period compared with one in the earlier period. Total perinatal deaths were not reported for either period. Citation: Chiara Dell’Utri, Elisabetta Manzoni, Sonia Cipriani, Claudio Spizzico, Andrea Dell’Acqua, Giussy Barbara, Fabio Parazzini, Alessandra Kustermann. Effects of SARS Cov-2 epidemic on the obstetrical and gynecological emergency service accesses. What happened and what shall we expect now? European Journal of Obstetrics & Gynecology and Reproductive Biology, Volume 254, 2020, Pages 64-68, ISSN 0301-2115, https://doi.org/10.1016/j.ejogrb.2020.09.006.&nbsp;

Paper 6 – four maternal deaths from suicide & two women murdered during UK lockdown

Four women died from suicide during pregnancy or soon after birth and two recently pregnant women died from domestic violence in the UK, between 01/03/2020 and 31/05/2020,causes (click here or ref.-201-mbrrace-uk-maternal-covid-19-report-final-002)). Citation: Knight M, Bunch K, Cairns A, Cantwell R, Cox P, Kenyon S, Kotnis R, Lucas DN, Lucas S, Marshall L, Nelson-Piercy C, Page L, Rodger A, Shakespeare J, Tuffnell D, Kurinczuk JJ on behalf of MBRRACE-UK. Saving Lives, Improving Mothers’ Care Rapid Report: Learning from SARS-CoV-2-related and associated maternal deaths in the UK March – May 2020 Oxford: National Perinatal Epidemiology Unit, University of Oxford 2020.

Paper 5 – no change in extremely preterm births during lockdown in the SafeBoosC-III consortium trial centres

In this Medxiv preprint the rate of extremely preterm births (<28 weeks) in 46 neonatal intensive care units participating in the SafeBoosC-III trial, did not alter during the three months of most rigorous lockdown, compared with the corresponding three months of 2019 (click here or 2020.10.02.20204578v1.full). Citation: Marie Isabel Rasmussen, Mathias Luehr Hansen, Gerhard Pichler, Eugene Dempsey, Adelina Pellicer, Afif EL-Khuffash, Shashidhar A, Salvador Piris-Borregas, Miguel Alsina, Merih Cetinkaya, Lina Chalak, Hilal Ozkan, Mariana Baserga, Jan Sirc, Hans Fuchs, Ebru Ergenekon, Luis Arruza, Amit Mathur, Martin Stocker, Olalla Otero-Vaccarello, Tomasz Szczapa, Kosmas Sarafidis, Barbara Krolak-Olejnik, Asli Memisoglu, Hallvard Reigstad, Elzbieta Rafinska-Wazny, Eleftheria Hatzidaki, Zhang Peng, Despoina Gkentzi, Renaud Viellevoye, Julie De Buyst, Emmanuele Mastretta, Ping Wang, Gitte Hahn, Lars Bender, Luc Cornette, Jakub Tkaczyk, Ruth del Rio, Monica Fumagalli, Evangelina Papathoma, Maria Wilinska, Gunnar Naulers, Iwona Sadowska-Kakrawczenko, Chantal Lecart, Maria Luz Couce, Siv Fredly, Anne Marie Heuchan, Tanja Karen, Gorm Greisen Extremely preterm infant admissions within the SafeBoosC-III consortium during the COVID-19 lockdown  medRxiv 2020.10.02.20204578; doi: https://doi.org/10.1101/2020.10.02.20204578

Paper 4 – fall in very & extremely low birthweight infants during lockdown in Limerick, Ireland

The rate of birth of both very low birthweight and extremely low birth weight infants reduced significantly in Jan-April 2020 compared witht the same period over the preceding 10 years (click here or e003075.full). Citation: Philip RKPurtill HReidy E, et al Unprecedented reduction in births of very low birthweight (VLBW) and extremely low birthweight (ELBW) infants during the COVID-19 lockdown in Ireland: a ‘natural experiment’ allowing analysis of data from the prior two decades. 

Paper 3 – halving of hospital births & increased perinatal mortality during lockdown in Nepal

Between Jan 1 and May 30, 2020, births in nine hospitals in Nepal halved during the latter 5 lockdown weeks, and stillbirths and neonatal mortality rose significantly (click here or PIIS2214109X20303454 (1)). Citation: KC, Ashish et al. Effect of the COVID-19 pandemic response on intrapartum care, stillbirth, and neonatal mortality outcomes in Nepal: a prospective observational study. The Lancet Global Health, Volume 8, Issue 10, e1273 – e1281

Paper 2 – fall in extreme prematurity during lockdown in Denmark

Using a national database the numbers of extremely premature singleton births was significantly lower between 12 March and 14 April 2020 than the previous five years (click here or fetalneonatal-2020-319990). There was no significant difference in other gestational age categories. Citation: Hedermann G, Hedley PL, Bækvad-Hansen M, Hjalgrim H, Rostgaard K, Poorisrisak P, Breindahl M, Melbye M, Hougaard DM, Christiansen M, Lausten-Thomsen U. Danish premature birth rates during the COVID-19 lockdown. Arch Dis Child Fetal Neonatal Ed. 2020 Aug 11:fetalneonatal-2020-319990. doi: 10.1136/archdischild-2020-319990. Epub ahead of print. PMID: 32788391; PMCID: PMC7421710.

Paper 1 – rise in stillbirths at a London hospital

St George’s hospital in South London noted a rise in stillbirths between February 1 & June 14, 2020 compared with the previous four months (click here or jama_khalil_2020_ld_200076). Neonatal deaths were not reported. There were no significant differences in preterm birth rates. Citation: Khalil A, von Dadelszen P, Draycott T, Ugwumadu A, O’Brien P, Magee L. Change in the Incidence of Stillbirth and Preterm Delivery During the COVID-19 Pandemic. JAMA. 2020;324(7):705–706. doi:10.1001/jama.2020.12746

Jim Thornton, Keelin O’Donoghue & Kate Walker

Beth Rowley

September 27, 2020

Supporting artists during lockdown

   

If your spine tingled to the introductory music to the BBC drama Strike (click here) you’re a Beth Rowley fan. She comes from my birthtown, Bristol, and has released two albums. I think she’s right up there with Adele and Amy Winehouse. But it was through Strike that I discovered her. Normally I’d have played her on Spotify and checked if she ever performed near Nottingham. But she won’t be touring now.

Until streaming came along, musicians used to make most of their money from LP & CD sales. Then live performance took over, surely a good thing.  Now that has stopped we need to go back to buying CDs. Her latest Gota Fria is £11.99 on Amazon, and an extra 95p on her own website. I love Amazon but they are doing well out of lockdown. I still have a job and less to spend my money on, so the latter it was (click here).

It’s a wonderful record. Time to buy Little Dreamer.

Jim Thornton

OASI care bundle evaluation project

September 23, 2020

A well-conducted study, but an unclear result

I admit it. I was sceptical. A stepped wedge (type of cluster) trial evaluating a “care bundle” (leaflets, a manoevre called the “Finnish grip”, 60o episiotomy & routine rectal examination) with, at best, a shaky evidence base (click here & here), evaluated by researchers who clearly already believed in it, and driven by two political organisations (RCM & RCOG) whose leaders felt that “something must be done” and were claiming success even before it started (2016 links no longer available). When the project ended, and more press releases announced success (2018 links not available), without any results appearing for over two years, I feared the worst; sample size changes, centres excluded for “low compliance”, participants disappearing from analysis groups, outcome switching, statistical shenanigans.

The “Finnish grip” is a bit odd too. Although mentioned on the Care Bundle website (click here), it doesn’t appear in the protocol or trial registry – I did a word search. Both call the 3rd element “Manual perineal protection”. The “Finnish grip” is mentioned, but not described, in the main trial report, and the references cited as sources (click here and here) describe it as “a technique for guiding the head through the introitus by gripping the baby’s chin with a flexed middle finger of the other hand”. They both refer to (Pirhonen et al 1998 click here) as the original source. In 1998 Jouko Pirhonen was a trainee in Lund, Sweden, and he is now a professor in Oslo, Norway. But Pirhonen is a Finnish name, and his co-authors included three obstetricians (no midwives) from Finland. They wrote:

“The delivery assistant presses the baby’s head with her left hand to control the speed of crowning through the vaginal introitus. Simultaneously, using the thumb and index finger of the right hand to support the perineum while the flexed middle finger is used to take a grip on the baby’s chin. When a good grip has been achieved, the woman is asked to stop pushing, to breathe rapidly, while the midwife slowly helps baby’s head through the vaginal introitus. When most of the head is out, the perineal ring is pushed under the baby’s chin.”

This is anatomically impossible, unless the flexed middle finger enters the rectum – surely they don’t mean that! – and even then it would be a stretch to reach the chin. Something probably got lost in translation. In practice it’s likely that midwives using the Care Bundle controlled delivery of the head by perineal pressure and discouraging maternal pushing.

I confess I feared the whole study would shed more heat than light on the topic, and together with a colleague, Hannah Dahlen, wrote a grumbling opinion piece (click here).

But the results are in (click here or gurol-urganci), together with a qualitative study of the implementation process (click here or bidwell), and I’m eating my words.

The study was registered (click here), and the protocol published (click here). Registration was a bit late 22/09/2017 – the project ran from 1 October 2016 and 31 March 2018 – but that’s made clear in the paper, and the protocol had been publicly available since January 2017. There’s no reason to believe either was written after peeking at the data.

Four regions, each containing a mixture of different size and type of birth unit were studied over the same 18-month period, with routine data collected all through. Only four randomised units is rather few, but unavoidable due to funding contraints.

Regions were randomised to have the care bundle taught and implemented sequentially over months 4-6, 7-9, 10-12 or 13-15 respectively. These transition periods were excluded from analysis. This left four 3, 6, 9 or 12-month duration baseline phases, and four same duration evaluation phases to compare. The Consort flow diagram, for some reason relegated to supplementary material* (click here), shows the design nicely. Exclusions were all for objective reasons, Caesarean, multiple or still-birth and did not alter over the trial.

All women having a singleton vaginal birth were included and the size of the before and after groups was approximately equal (baseline 27,668, evaluation 27,932). This is reassuring. Differential rates of Caesarean birth, baseline 12,807 (31.6%) v evaluation 12,472 (31.3%), had not muddied the waters.

The primary, indeed the only, endpoint was OASI (obsteric anal sphincter injury) as recorded on the hospital routine database, and the primary analysis was done after statistical adjustment for a range of potentially relevant factors. Here are the relevant methods as reported in the paper.

“We used multi-level logistic regression to estimate adjusted odds ratios (aOR) […]. The regression model included a linear term for calendar time […] a random effect to account for clustering at both region and unit levels and individual case-mix factors (maternal age, ethnicity, body mass index, parity, mode of birth and birthweight).”

And here they are as planned in the protocol.

“We will use logistic mixed effects regression to model the log odds of sustaining an OASI, with a fixed effect for each step and a random effect to account for clustering at the unit level. The model will include a linear secular trend and also adjust for risk factors for OASI (maternal age, BMI, ethnicity, mode of delivery, episiotomy, birthweight, prolonged labour, and shoulder dystocia).”

Perfect. The planned analysis was done.

And the result. The recorded OASI rate decreased from 911/27,668 (3.3%) baseline phase to 817/27392 (3.0%) evaluation phase (aOR 0.80, 95% CI 0.65–0.98) p=0.03.

But what does it mean? Did manual perineal protection prevent 94 women suffering OASI? Did the 60o episiotomy do the trick? Did a few women read the leaflet and, fearful of OASI, choose Caesarean? Or a mixture of all three? Or was the difference in the “diagnosis” of OASI?

The original research, which had inspired the trial, had shown a much larger increase in recorded OASI from 1.8% in 2000 to 5.9% in 2011 (click here). The authors of that study, who included many of the current trial authors, had concluded that “improved recognition of tears following the implementation of a standardised classification of perineal tears was the most likely explanation”. They were surely correct. Diagnosing OASI is not easy. It can be both over and underdiagnosed. An effect size of 0.3% in an endpoint which can vary by 4.1% due “improved recognition” must be susceptible to ascertainment bias.

And this was an “open” trial. Staff may not have realised they were in the baseline phase but they certainly knew about the implementation and evaluation phases. This is from the qualitative study report (click here or bidwell).

“Many participants spoke about a well advertised launch, which created a lot of ‘noise’ and got the project off to a good start: ‘Yes, we had a launch day at the unit….on that day they had many sessions talking about it. We had the models.….they had pictures of how you would give an episiotomy, things like that, to add to this…There was quite a lot of noise about this. (Midwife)'”

“Many talked about the positive and passionate way with which the champions delivered the training. ‘She [the champion] was like a hound! …. if you weren’t trained and you were on her list, she would hunt you down….She would come in early to catch people on night shifts and stuff……If you have somebody like that who is passionate about the training and gets the training done, then I think that’s what makes it better. (Obstetrician)'”

How did midwives and doctors in the midst of such a campaign classify borderline cases?

Consider, for example, a woman with suspected OASI transferred to the operating theatre for repair, who when reviewed under good light by a senior staff member was found to have an intact sphincter? Would the theatre staff recode the planned operation to “repair of episiotomy”? In the baseline phase they might not even have realised the diagnosis had changed. But in the implementation and evaluation phases, with champions “hounding” everyone, the coding surely would be altered. Of course the effect might also have gone in the other direction. Routine rectal examination might have increased diagnosis. We just don’t know.

These doubts matter because the underlying evidence base for each component of the bundle is so weak. Well designed individually randomised trials do not support manual perineal protection (click here), there have been no trials of 60o angle episiotomy, and rectal examination after normal birth in the absence of a tear makes no sense (click here).

We can all support information giving, avoiding midline episiotomies and doing rectal examinations in the presence of tears. But the debate over manual perineal protection, extremely lateral episiotomy, and routine rectal examination even after normal birth with an intact perineum, will surely continue.

Jim Thornton

Footnote. *The Consort flow diagram belongs in the main report, especially for complex designs. Come on BJOG!

An improved martini

September 4, 2020

Not a better recipe, but a better technique – freezing water in the glass

Last week, dipping into Kingsley Amis’s Everyday Drinking (click here) on holiday, I came across this under “the Dry Martini”.

“A couple of hours before the party get your glasses together. They should be on the small side – the second half of a too large martini will have become too warm by the time the average drinker gets to it – and have some sort of stem or base to prevent the hand-imparting warmth. […] Fill each with water and put in the refrigerator.”

I read it as “put in the freezer”. As Amis says.

“It is more important that a cold drink should be as cold as possible than that it should be as concentrated as possible.”

I should have realised that in Amis’s day the freezer section of a domestic fridge would barely hold a tray of ice; no chance even a small martini glass. But I’ve got a modern monster freezer, so undaunted I made my martini. Freezing the water in the glass in emulation, and using a modern vermouth, Regal Rogue – Daringly Dry (click here), to annoy him. Click here for the video. It worked a treat.

    

Only afterwards did I realise he’d never meant “freeze the ice in the glass”. He wrote.

“While the jug is standing, empty the water out of the glasses and drop a bit of lemon rind in each.”

Nor, from a brief google search, does anyone else. People add ice cubes, sometimes large ones to avoid the over-dilution problem, but never my technique.  I offer it to the world.

Jim Thornton

6 September update

I was wrong, or rather right first time. Amis did advocate freezing water in the glass, albeit ten years later. My volume is a compendium of three books; On Drink (1974), Everyday Drinking (1983) and How’s Your Glass? (1985). The quotations were from On Drink. By the time of Everyday Drinking he must have got a larger freezer. He writes.

“The best Dry Martini known to man is the one I make myself. In the cold part of the refrigerator I have a bottle of gin and a small wineglass, half full of water that has been allowed to freeze.”

“When the hour strikes I half fill the remaining space with gin, flick in a few drops of vermouth and add a couple of cocktail onions, the small white hard kind. Now that is a drink.”

Oh well. Nothing new.

Lockdown cocktails

July 13, 2020

Drinking – not paddling – down the Loire

Our small gang have been walking the Camino de Santiago (click here or here), and more recently canoeing the Loire (click here or here). When lockdown put paid to our 2020 trip from Blois to Saumur we met up on Zoom instead, and inspired by Stanley Tucci (click here and here), drank cocktails. Here they are; some with a poem.

Hemingway’s daiquiri (click here).

Philip Larkin’s gin & tonic (click here).

A “No”groni (click here).

A conventional Negroni under adverse conditions (click here).

James Bond’s Vesper martini (click here).

The Gilles Villeneuve martini (click here).

A Radish Walked into a Bar (click here)

The Kingsley Amis martini (click here).

Forgive the rough edges. Filmed on different phones, and once made you’ve gotta drink it, so a second take wouldn’t help.

We also drank appropriate wine from the brothers Yapp, but no videos of that. First day sweet Vouvray (click here), 2nd a dry one (click here), 3rd Bourgueil (click here), 4th Saint-Nicolas-de-Bourgueil (click here) and 5th Saumur (click here). Forgotten the others, but to end with, we popped open a fizz (click here). All more expensive than our usual riverbank plonk, but I guess we’d saved on the ferry crossing. 

Lockdown 2

First zoom cocktail for lockdown 2, the Brexitini (click here).

The Euro martini (click here).

The Roman Moselle citrus sangria a la Kingsley Amis (click here).

Susie’s negroni (click here).

A Moselle martini with a nod to Michael Portillo (click here).

A French sidecar (click here).

A real martini (click here).

Whisky sour with a fairy egg (click here).

Jim Thornton

Wild swimming in the river Trent.

June 6, 2020

Downstream of Nottingham

One of my projects for the 2020 lock-down summer has been to swim the best spots. If you don’t mind disclaimer forms, safety briefings, and signing in and out [1], there’s a dedicated centre on Colwick Park lake (click here). But that’s not for me. For swimming spots in the gravel pits click here.

These swims are for privateers. All, bar Farndon, are on the left, northern, bank. I’ll try to remedy that in any updates. Update 16 June 2020 – Cromwell. 1 June 2021 – two right (south) bank spots, East Stoke and Stoke Wharf added. 25 July 2021 – Stoke Bardolph revised.

Stoke Bardolph – Left bank 

Right in front of the Ferry Boat pub, two or three slipways and landing stages provide easy access. Great spot. Crowded on sunny days. Alternatively follow the first straight section of the metalled riverside path upstream towards Bardolph weir; many good gravelly entry points.

Stoke Bardolph is about 100 yards upstream of the discharge from Severn Trent’s, state of the art, treatment plant! Upsteam’s good!.

Gunthorpe – Left bank

Park in front of the Unicorn Hotel, and swim off the metal boat ramp next to the water ski club.

      

Don’t forget Gunthorpe gravel pit. Some fishermen claim swimming is prohibited there, so be discreet. Walk under the road bridge for about 1/2 mile, and turn right immediately after footbridge. Lots of easy access and a lovely stony bed. Magical.

 

Hoveringham – Left bank 

On sunny days the parking along the river bank road gets full early, but the bank is stony and access easy. Any slight smell is from muck-spreading on the surrounding fields, not the river. Another good spot.

Hazleford – Left bank 

One of my favourites. The metal slipway at the end of the road provides easy access, albeit slippery. The car park is private and locked, but there’s plenty of space on the road. The boat moorings leave a sheltered area near the slipway for those who are nervous of venturing into midstream.

If the slipway’s crowded try upstream, along the river path, past the moorings and caravan park. Plenty of the fishing pegs have good access. I swam by the Km 23 mark.

Downstream less good. Although plenty of access below the weir, the water tends to be frothy.

East Stoke – Right (south) bank. New 2021

Travelling south from Farndon, on the old A47 (Fosse Way), turn right into East Stoke and follow the unsurfaced road past Stoke Hall, all the way to the river opposite Fiskerton. Ample parking and a good path to a ricket wooden stage. Muddly, but the stage helps your balance. A good spot but on sunny days an audience from the Bromley Arms opposite.

Fiskerton – left bank

Park about 1/4 mile downstream of the Bromley Arms and walk upstream. The problem here is the high river wall. Don’t even think of jumping! Some pontoons are barred off, and they all have “private mooring” signs, but no-one has ever objected to me using one of the open ones. Getting back on is tricky. Swim round to the river wall – shallow stony bed – and step back on with your dignity intact.

        

Peg 18 below Fiskerton – left bank

Park as above and walk downstream. Nottingham Piscatorial Society have marked their fishing pegs with numbers set in the grass. Peg 18’s label is obscured but it’s the best spot. If you avoid the fishing season, usually quiet enough for a skinny dip.

Stoke Wharf – Right (south) bank. New 2021

Midway between Farndon and East Stoke on the Fosse Way, a barred, field entrance has room to park. Fifty yards from the road, each fishing peg has beautiful stone steps providing easy access. Peg 13 for me! Outside of the bend but I just about made headway against the current. The downstream pegs provide easy exits for weaker swimmers. A lovely private spot.

Farndon – Right (South) bank

From the roundabout at the south end of Newark bypass, take the B166, the old Fosse Way to Farndon. Turn right, then left, initially following signs to Farndon marina. Then ignore the 2nd right to Farndon marina and follow signs to The Waterfront. Sandy ramp. Lovely.

North Muskham – left bank

Down Ferry Lane to the Muskham Ferry pub, and swim off the slipway. Slightly muddy, but nothing to trouble a wild swimmer.

Cromwell – left bank

A farm track, signed as a footpath, from Cromwell village, crosses the A1 as a single track road to the lock. Plenty of parking at the sign which says “no parking or boat launching at the lock”. Upstream of the lock, by two brick barbeques, a ramp leads to a pontoon with steps into the water at each end. Perfect.

Carlton-on-Trent – left bank

Head for the Church, and Ferry Lane. The road to the river, Perry Lane, is full of “no access to river” signs so I parked back up in the village. In fact there is parking. Two possible swim spots. Upstream of the commercial wharf, access looks easy via stony muddy banks, but I was nervous of a metal detectorist on the opposite bank.

The wharf itself has a ladder down to the water, but it’s high and muddy and my courage failed again. About 1/4 mile downstream is best. Stony and a bit muddy, but a good gap in the nettles. The opposite bank also looked inviting.

Carlton is downstream of Cromwell weir, so right at the tidal limit. But it’s on the outside of the bend so you’re straight into fast flow. I kept station, but only just. If you got carried downstream, you’d end up clambering out through nettle beds.

I’ve never swum below Carlton. There must be good spots but I doubt they beat the ones above.

Jim Thornton

Footnote

  1.  One of the annoyances of river swimming is people banging on about the risks. Learn to swim and avoid the river in spate or near weirs. Weil’s disease is rare; only about 30 recreational cases, and less than one death, per year in the UK. Given the number of people coming into contact with river water, the drive to the riverbank is probably more risky, but avoid swimming with an open cut. Gastroenteritis is less of a risk for older swimmers who don’t wear wet suits; we don’t stay in so long, have developed antibodies and are wise enough not to swallow.

Covid-19 pregnancy news reports

May 17, 2020

Primary newspaper sources

In roughly reverse order. Updated regularly. Click here for ripe-tomato.org’s Covid-19 in pregnancy navigation page. From 14 January “Vaccine in pregnancy news reports” included. For access to those US sites which are blocked in the EU, not many, I use https://www.proxfree.com/ 

Note – numbering error 319 to 520. The total number of reports are 200 fewer than the latest number would imply.

1 August 2021

849. Stacey Knights, age 27, from Middlesborough, UK, contracted Covid in January 2021, at 12 weeks gestation (click here). She recovered. Report 31 July

848. Suma (an alias), age 37, contracted Covid, and gave birth at 31 weeks, while on a ventilator at Apollo Hospitals in Bengaluru, India (click here). She spent 36 days on ECMO, and a further 19 in ICU, but recovered. The baby also survived. Report 1 August.

847. Lorena Betancourt, age 26, from Argentina, gave birth with Covid and spent a month in intensive care (click here). She died on July 15. Her daughter survived. Report 1 August

31 July 2021

846. Over 227,000 pregnant women have received their first dose of anti-coronavirus vaccine in India (click here). 78,838 in Tamil Nadu, 34,228 Andhra Pradesh, 29,821 Odisha, 21,842 Madhya Pradesh, 18,423 Kerala and 16,673 in Karnataka. Report 30 July. Vaccine in pregnancy news report

845. Zoey Edwards, 32, from Preston contracted Covid. and was admitted to ITU at Royal Preston Hospital and delivered by Caesarean both on June 25 at 35 weeks (click here). She had not been vaccinated. She and the baby survived. Report 31 July.

844. Dr. Jane Martin from Ochsner Health in Louisiana, got vaccinated in the 34th and 37th weeks of her recent pregnancy and gave birth to a healthy baby (click here). Report 31 July. Vaccine in pregnancy news report

30 July 2021

843. An unnamed woman, aged less than 30, who recently gave birth, is now seriously ill with Covid, in Hendrick Medical Center, Abilene, Texas (click here). Report 30 July

842. Dr. Rebecca MacDonell-Yilmaz got the Pfizer-BioNTech vaccine while pregnant (click here). Report 29 July Vaccine in pregnancy news report

29 July 2021

841. Imogen, 29, from Brighton got vaccinated in the second trimester (click here). Report 29 July Vaccine in pregnancy news report

840. Carrie Limon contracted Covid and gave birth at Sutter Roseville Medical Center, California, on May 7 (click here). Her son required NICU treatment, and she required ECMO, but both survived. She had not been vaccinated. Report 29 July

28 July 2021

839. Former olympic gymnast Shawn Johnson, age 29, tested positive for COVID-19 early in pregnancy and recovered (click here). She gave birth to a healthy baby by Caesarean on 19 July. Report 28 July.

838. An unnamed a 40-year-old woman with severe Covid gave birth two weeks ago in ICU in Murcia, Spain (click here). She died on 27 July. Report 28 July

837. An unnamed woman with Covid was delivered by Caesarean at James Cook hospital in Middlesbrough this week (click here). The baby is doing fine. The mother remains ventilated. Report 28 July

836. Dr Gesti Wira Nugrayekti, age 25, who was training in anesthesiology at Airlangga University in Surabaya, contracted Covid and gave birth prematurely early in July (click here). Three weeks after the birth she died. She had not been vaccinated. In the same report, Indiana Alawasilah, age 33, from Bandung, contracted Covid during the third trimester in 2020. She required oxygen therapy but recovered. Report 28 July

835. Patience Atuhaire contracted Covid at 8 months gestation (click here). She was delivered by caesarean at Mulago Hospital, Uganda in February 2021, and required ICU treatment. Her and the baby survived. Report 27 July

834. Supraja Reddy Yeruva, age 27, got Covid in pregnancy in June and required ICU care at a private hospital in Hyderabad (click here). A month later she remains there. Report 29 July

833. Early in the pandemic two unnamed women who gave birth at Marin Health Medical Center, became critically ill with Covid and had to be transferred to University of California, San Francisco (click here). Both survived. Report 27 July

832. Clair Griffiths, age 43, contracted Covid and gave birth to a healthy son by Caesarean on 18 July (click here). Two days later she was readmitted to hospital with pneumonia, where she remains. Report 28 July

27 July 2021

831. Emmy Rossum, age 34, star of TV comedy “Shameless” got vaccinated during pregnancy and had a healthy daughter (click here). Report 27 July Vaccine in pregnancy news report

830. An unnamed 38-year-old woman with severe Covid gave birth at Barzilai Medical Center in Ashkelon, Israel, on 24 July (click here). Her daughter is fine but the mother’s condition deteriorated and she is presently on ECMO at the Wolfson Medical Center in Holon. She had not been vaccinated. Report 25 July.

829. Gemma Wilkinson, 38, got her first vaccination dose late in pregnancy and gave birth to a hea;thy girl (click here). She had her second dose while breastfeeding. Report 27 July. Vaccine in pregnancy news report

25 July 2021

828. Maria Garza, from Leander, Texas got vaccinated while pregnant in February 2021 and gave birth normally in July (click here). She had previously had mild Covid in 2020, and her husband had died of Covid in February 2021. Report 24 July. Vaccine in pregnancy news report

24 July 2021

827. Glorimar required long term ICU care at Wesley Medical Center, Wichita, Kansa, while she was pregnant and gave birth nearly a year ago (click here). Mother and baby recovered. Report 24 July

826. At Christmas 2020, Sally, age 38, contracted Covid at 20 weeks (click here). The pregnancy outcome was not reported. Report 24 July

22 July 2021

825. An unnamed woman died shortly after giving birth in Ndola Teaching Hospital, Zambia (click here). Her cause of death and Covid status were not reported, but her partner had died of Covid three days earlier. Report 22 July

824. In Thailand, between December 2020 and July 3rd 2021, 581 pregnant women contracted coronavirus and nine died. 40 babies were born infected and four died. (click here). Report 22 July

823. Three unnamed pregnant woman, and two who have recently given birth, are currently hospitalised in Israel with Covid (click here). All are “in good condition”. Report 22 July

21 July 2021

822. Violinist Izzy Judd tested positive for SARS-CoV-2 early in her third pregnancy (click here). She recovered and the pregnancy is ongoing. Report 21 July

20 July 2021

821. More than 100 pregnant women were admitted to hospital in each of the last two weeks [presumably weeks ending 2nd & 9th July] with COVID-19. No pregnant women who had received both doses of vaccine have been admitted to hospital since the vaccination programme began. Only five women admitted have received a single dose (click here). Report 15 July. Vaccine in pregnancy news report.

821. Peru is prioritizing pregnant women in its vaccination campaign (click here). Report 13 June Vaccine in pregnancy news report.

19 July 2021

820. Anshuma Chauhan, 30, died from Covid in April shortly after giving birth by Caesarean in Delhi, India (click here). Report 8 June.

819. Eight unnamed pregnant women died of Covid in Uruguay between April 29 and June 8 (click here). Report 2 July

818. Elisabeth Soto, 38, died from Covid on 19 April, six days after giving birth in Lomas de Zamora, Argentina (click here). Report 9 July

817. Oksana Shelomentseva had severe Covid and gave birth by Caesarean at 32 weeks in Irkutsk, Russia (click here). She required 51 days ventilation in ICU, but survived. Her baby also survived. Report 12 Jan 2021

816. Helen Singh, 22, from Fiji, contracted Covid on 22 June and gave birth soon after (click here). Mother and baby recovered. Report 19 July

18 July 2021

815. An unnamed 33-year-old woman in Thessaloniki, Greece, has Covid in her 6th month of pregnancy, and is being ventilated (click here). Report 18 July

814. Thirty three pregnant women died from Covid in Nepal between March 2020 and June 2021 (click here). Report 18 July

813. Dr Amy Manos age 31, from New South Wales, Australia, got vaccinated at 26 weeks gestation (click here). She is due in September. Report 18 July. Vaccine in pregnancy news report.

812. Angela MacDonald got vaccinated in April two weeks after giving birth (click here). Report 18 July Vaccine in pregnancy news report.

14 July 2021

811. About 150 pregnant women have tested positive in Fiji (click here). None have died. Report 14 July

810. An unnamed 22-year-old pregnant woman with Covid-19 is intubated at Nicosia General Hospital, Cyprus (click here). Report 14 July

13 July 2021

809. Vong Daneth, age 29, from Cambodia, contracted Covid at 7 months and was delivered by Caesarean (click here). She died but her baby survived. Report 13 July

808. Rakhi Mandal Biswas, age 31 contracted covid and was delivered by Caesarean at Kolkata Medical College and Hospital, at 32 weeks, on 21st June (click here). She died, but the baby survived. Report 13 July

807. Two unnamed women, aged 29 and 40, with Covid, one pregnant and one recently delivered are in ITU in Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar, Murcia, Spain (click here). Both are reportedly on ECMO. The baby who has been delivered is alive. Report 13 July

806. Sophie Forrester, 28, contracted Covid and gave birth by Caesarean on on July 6 at Forth Valley Royal Hospital (click here). Mother and baby recovered. Report 13 July

12 July 2021

805. Shubha Deshmukh got vaccinated at eight months gestation in Pune, India (click here). Report 12 July Vaccine in pregnancy news report.

804. Vanessa de Oliveira Silverio, age 33, from São José dos Campos, in São Paulo state contracted Covid at 34 weeks and died during a Caesarean birth in March 2021 (click here). Her baby survived. Fabiana Alves Sousa, age 31, from Ceará state in the north-east Brazil also contracted Covid and was delivered by Caesarean at 30 weeks. Both mother and baby survived. Report 12 July

11 July 2021

803. An unnamed woman, age 22, with HIV and Covid-19, gave birth at Diphu Medical College and Hospital, Assam, India on 9 July (click here). A woman named SR Das, also with covid, gave birth the same day. Both babies are healthy. Report 11 July

7 July 2021

802. Kalyani Agrahari contracted Covid at 32 weeks (click here). She was admitted to Mahila Chikitsalaya (Women’s hospital) in Jaunpur, and died on April 24. The baby’s outcome is not reported. Report 9 June

801. Sari Azalea Yuliani, age 24, contracted Covid at 37 weeks (click here). She was delivered by Caesarean at Dr Esnawan Antariksa Air Force Hospital, Jakarta, on 30 June, and died two days later. Her baby tested negative, but had other complications from the birth, and also died. The report also states that, according to the Indonesian Obstetrics and Gynaecology Association (POGI), more than 500 pregnant women have tested positive since the pandemic began, with 4.5% needing ICU treatment, and about 3% dying as a result of the disease. Report 7 July

6 July 2021

800. Kavisha Patel (a pseudonym) died from Covid in June, after giving birth at 32 weeks in Ahmedabad, India (click here). The baby survived. Report 1 July.

799. Ashton Reed, 25, contracted Covid-19 at 30 weeks gestation (click here). She required ECMO at University of Arkansas for Medical Sciences (see source 795) and gave birth by Caesarean on May 27.  Mother and baby survived. Report 29 June.

798. Between 1 April 2021 and 30 June 2021 the Mother & Child Hospital at Silchar Medical College in Assam has cared for 160 pregnant women with Covid (click here). Of 82 births, 43 were by Caesarean. There were two Covid-related deaths; report unclear if these were of mothers or babies. Report 1 July

797. An unnamed woman tested positive at 24 weeks gestation in April (click here). She gave birth by Caesarean at the Government Medical College & Hospital, Nagpur, India on 20 June. The baby weighed 2.3 kg, was preterm, had congenital heart disease, tested positive for Covid and died age 8 days. Report 4 July

796. Amrita Sundareswaran contracted Covid-19 at six weeks gestation and recovered (click here). She gave birth by Caesarean on 26 April and her baby developed breathing difficulties. The baby had anti-Covid antibodies and recovered. Report 4 July

1 July 2021

795. Three unnamed pregnant woman at University of Arkansas for Medical Sciences were on ECMO last week (click here). Report 30 June

794. Elizabeth Etherington, 40, received her second dose of the Pfizer vaccine at 34 weeks (click here). Report 24 June. Vaccine in pregnancy news report

793. Olivia Saxton got vaccinated in January. She conceived naturally in March and had her second dose at 13 weeks (click here). The pregnancy is ongoing. Report 30 June Vaccine in pregnancy news report

30 June 2021

792. Claudia Edwards, age 35, died from Covid at Princess Margaret Hospital in the Bahamas in May, the day after giving birth (click here). Report 30 June

29 June 2021

791. An unnamed woman with Covid-19 gave birth to a healthy baby at Soroti Regional Referral Hospital in Uganda (click here). The disease was mild and both recovered. Report 29 June

790. Since August 2020, 190 women with Covid have given birth at Maharaja Krushna Chandra Gajapati Medical College & Hospital, Brahmapur (click here). 109 were normal and 81 were Caesareans. Report 29 June.

789. Kate Barr, age 39, from Pittsburg, contracted Covid, gave birth on 13 May and died on 27 June (click here). Report 28 June

26 June 2021

788. Yesenia Lopez, age 34, from New York gave birth while on ECMO in April (click here). She and the baby recovered. Her husband had been vaccinated but she had decided against. Report 20 June. Vaccine in pregnancy news report

787. Jen Sizeland from UK got the Pfizer vaccine at 28 weeks (click here). The pregnancy is ongoing. Report 23 June Vaccine in pregnancy news report

786. Sara Edmond a clinical psychologist at the Veterans Affairs Connecticut Healthcare System contracted Covid in pregnancy (click here). Mother and baby are fine. Report 21 June

785. Puji Apriani from Kudus, Central Java, Indonesia, died undelivered from Covid-19, at Loekmono Hadi General Hospital (click here). Report 24 June

22 June 2021

784. Prum Lay, age 35, and Ul Srey Nouch, age 18, both had Covid and gave birth naturally at Poipet Referral Hospital, Cambodia (click here). Mothers and babies are fine. Report 22 June

20 June 2021

783. Angie Wells tested positive during her pregnancy but her symptoms were mild (click here). Her baby was born at home in Benoni, east of Johannesburg, and initially tested negative, but later became seriously ill and tested positive. Both survived. Report 20 June

782. Manju, wife of Bharat Sharma, gave birth on 21 April and died of Covid on 29 ASpril (click here). Her baby survived. Daksha w/o Devdutt Taviyad, gave birth on 19 May and died of Covid complications on May 30. The unnamed wife of Nitin Sodha also died of Covid during or after her pregnancy. All three babies survived. Report 20 June.

781. Thrupathamma, aged 21, had severe Covid-19 symptoms and gave birth by Caesarean at 37 weeks at Continental Hospital, Hyderabad, India (click here). She was treated in ICU. Her baby survived. Both tested negative. Report 20 June.

19 June 2021

780. Hunter McGrady, age 28, a plus size model in the United States, contracted Covid at seven months (click here). She recovered and the pregnancy is ongoing. Report 12 June. Update 8 July. She had a healthy baby (click here).

779. Priyali Sur, a Delhi-based journalist, contracted Covid in the 2nd trimester of pregnancy (click here). She recovered. Report 15 June

778. Rehab, the wife of Altuf Shamsi, who had severe Covid gave birth by Casarean on 29 April, and died of Covid complications on 11 May, in India (click here). Report 14 June

777. Thais Ferreira de Lomes required ventilation for Covid and gave birth at 28 weeks at the Grajau Hospital in Sao Paulo in March (click here). That hospital has observed at least one pregnant woman with Covid each week in 2021. Mother and baby survived. Report 18 June

776. Vidya Justin (age 25) of Korampallam gave birth to triplets by Caesarean at 32 weeks, Thoothukudi Medical College Hospital, in India, on 30 May (click here). She had Covid-19 and HELLP syndrome with liver and kidney failure, and was treated in ICU. She and the babies recovered. Report 16 June

775. An unnamed woman with Covid gave birth to twins on 17 June in Cambodia (click here). Both babies are healthy as is the sick mother. Report 18 June.

774. An unnamed woman age 36 with Covid gave birth in Tacloban city in the Philippines on 17 June (click here). Mother and baby are doing fine. Report 18 June

14 June 2021

773. An unnamed woman with Covid-19 gave birth to twins at six months gestation at the Western Visayas Medical Center in Mandurriao district, the Philippines, on 9 June (click here). The twins died the same day. Report 14 June

772. Dana Sy, age 27, tested positive for Covid-19 when she gave birth in July 2020 at the Chinese General Hospital and Medical Center in Manila (click here). Her baby was separated from her for a period. Both recovered. Report 14 June

771. Smita Panda, age 28, a staff nurse at the Acharya Harihara Cancer hospital in Cuttack, Odisha, India, got Covid-19 at 9 months gestation and gave birth on 22 April (click here). Seven days later she died of Covid, and a little later her husband died too. The baby survived. Report 14 June

770. Playback singer Shreya Ghoshal gave birth on 22 May and got vaccinated on 14 June (click here). Report 14 June. Vaccine in pregnancy news report

13 June 2021

769. Actress, Adite Malik, gave birth in March and got vacccinated in Mumbai, in June (click here). Report 13 June. Vaccine in pregnancy news report

768. Jennifer Nash from California, contracted Covid at 24 weeks in March 2021, and delivered by Caesarean at 29 weeks on 3 May (click here). She was cared for at Ronald Reagan UCLA Medical Center, and treated with ECMO. She came off the ECMO but remains in ICU. Report 13 June

767. Lindsay Bullock contracted Covid at 36 weeks and gave birth by Caesarean on 23 February at Yale New Haven Hospital (click here). She was ventilated for a week. Mother and baby recovered. Report 12 June

11 June 2021

766. Since May, 24 pregnant women with Covid have delivered at the District Hospital, Brandipora, Jammu and Kashmir, India (click here). Report 11 June

765. Nor Baizura Mohd Noordin contracted Covid in December 2020, and was admitted to ICU at Universiti Malaya Medical Centre, but not ventilated. She recovered, and gave birth two months later (click here). Report 10 June

764. An unnamed woman with Covid-19 was delivered by Caesarean on 10 June, at King George Hospital in Vizag, Andra Pradesh, India (click here). The mother had been on a ventilator for ten days and remains so. The baby is alive. According to the article, 28 pregnant women with Covid are currently in the same hopsital. Last month the figure was 90. Report 10 June

10 June 2021

763. April Mager contracted Covid-19 at just 4 weeks gestation and spent nine days in hospital (click here). She recovered but the pregnancy miscarried. Report 9 June

762. Natalia Worek, a nurse from Ontario, contracted Covid in the 3rd trimester, was delivered by Caesarean, and spent time in ICU (click here). Mother and baby both recovered. Report 9 June

9 June 2021

761. Shanetta Wilson contracted Covid in April at 6 months gestation, and after prolonged intensive care at George Washington University Hospital in Washington DC, died on 1 June (click here). She had not been vaccinated. Her baby had been delivered in May but had died age five days. Report 8 June

760. Dr Arfa Sajadin from West Bengal, contracted severe covid at 37 weeks, and required 10 days ventilation (click here). Mother and baby survived. Report 8 June.

759. KK Women’s and Children’s Hospital in Singapore vaccinated six pregnant women on June 8 (click here). They included Suzanna Farid Tang Shu Ling and Noriyah Abdul Rahman. Report 9 June. Vaccine in pregnancy news report.

758. Rebecca Benson from Maguiresbridge, Northern Ireland, gave birth at 26 weeks on Oct 14, 2020, and contracted covid in postnatally (click here). Report 8 June

8 June 2021

757. Dr Fatihah Shahrudin has severe Covid-19 and is being treated in ICU at the Sungai Buloh Hospital in Kuala Lumpur (click here). Her baby was delivered at 29 weeks. Report 7 June

756. Lucy Angel was vaccinated at 35 weeks gestation in May and has since given birth (click here). Natalie Wright decided against at 32 weeks. Report 7 June Vaccine in pregnancy news report

7 June 2021

755. Megan von Prittwitz from El Paso, has just given birth, and is currently being treated with ECMO in an Albuquerque hospital with Covid-related pneumonia (click here). Report 1 June

754. 225 women with Covid have given birth in Agartala Government Medical College, Tripura, India (click here). Of these, 198 were in the first wave, and 27 in the second. Report 3 June

753. Linzi Watkins, contracted severe Covid-19 at 21 weeks gestation (click here). She required four days ventilation at University Hospital of Wales in Cardiff. She recovered and gave birth normally on May 26. Report 1 June

752. Antonella, from Gioia Tauro, Italy, tested positive for SARS-CoV-2 early in her pregnancy (click here). She remained asymptomatic and gave birth normally. She attributed this to the scapular of St. Dominic Savio. Report 6 June.

751. An unnamed woman with severe Covid successfully gave birth by Caesarean on 4 June, in Prey Veng province, Cambodia (click here). Report 7 June

750. Diptimayi Devi died of Covid on May 30, 2021, the day after giving birth at Maharaja Krushna Chandra Gajapati Hospital, Brahmapur, India (click here). She was an Angwanwadi worker, a type of community health carer. Report 7 June

749. Jalpa Patel from Piplaj of Anand, India, died from Covid on April 26, 2021, the day after giving birth (click here). Report 7 June

4 June 2021

748. The rate of Covid is higher in the pregnant than non-pregnant population in Russia (click here). No numbers given. Report 24 January 2021

747. Over 390 pregnant women in Russia had contracted Covid-19 by April 2020 (click here). Report 27 April 2020

3 June 2021

746. Tina Wesley from Calgary, Canade, gave birth by Caesarean on 26 April while ventilated (click here). Report 2 June

745. Deeptimayee Devi died from Covid on 31 May, the day after giving birth at MKCG Medical College and Hospital in Bramapur, India (click here). Report 2 June

744. Briana Mike from Germantown, Maryland gave birth on 25 May after weeks on a ventilator at the University of Maryland Hospital in Baltimore (click here). Report 3 June

1 June 2021

743. Amila Khatun had Covid-19 and gave birth at Biswanath Civil Hospital, Assam, India, on 31 May (click here). Report 1 June

742. An unnamed woman from Darsheth village in Palghar district, Maharashtra, India, tested negative but her baby tested positive (click here). Report 1 June

741. Ruchi Panchal had Covid-19 and died during delivery by Caesarean section on 11 May at Surat District hospital in Gujarat, India (click here). The baby survived. Report 1 June

29 May 2021

740. Laura Durcan was vaccinated during pregnancy and gave birth normally (click here). Report 29 May. Vaccine in pregnancy news report

739. Natalia Worek contracted Covid-19 at 32 weeks and was delivered by Caesarean at St. Joseph’s Healthcare in Hamilton, Ontraio (click here). Trisha Mayer contracted it at 34 weeks and also gave birth by Caesarean. A third unnamed infected woman also gave birth by Caesarean. Report 29 May

738. Lauren Mannell tested positive the day after giving birth by Caesarean on 3 Jan 2021 (click here). Her baby was severely hypoxaemix at birth, and required cooling, but recovered. Report 29 May

28 May 2021

737. About 100 women with Covid-19 have given birth at Jawahar Lal Nehru Memorial Hospital in Srinagar (click here). Report 27 May

736. An unnamed woman gave birth at SS Hospital in Banaras Hindu University, Varanasi, Uttar Pradesh on May 25. She tested negative but the baby tested positive (click here). Report 28 May

735. Taíssa Souza, from Vitória, Brazil, died from Covid-19 three weeks after giving birth (click here). Bárbara Cesar, from the same city was pregnant with twins when she contracted Covid-18. She required three weeks ventilation. The babies were delivered by Caesarean and healthy. Report 27 May

26 May 2021

734. An unnamed woman contracted Covid-19 and gave birth safely in Karimganj Covid Hospital, Assam, on 24 May (click here). Report 26 May

733. Nine women with Covid-19 gave birth at Niloufer hospital in Hyderabad (click here). The babies initially tested negative but later tested positive. The babies recovered. Report 26 May

732. Kate Mulholland was vaccinated (Pfizer) at 33 weeks (click here). The pregnancy is ongoing. Report 26 May. Vaccine in pregnancy news reports

731. Over 200 women with Covid-19 have given birth to healthy babies in the Indian state of Jammu & Kashmir (click here). Eighty in Maternal and Child Health (MCH) Hospital, Gandhi Nagar Jammu. More than 12 in the district hospital Bandipora in Kashmir Valley. Report 25 May

730. The unnamed wife of Shailan Tiwari, who suffered from idiopathic thrombocytopaenic purpura, contracted Covid-19 while pregnant and gave birth sucessfully at Queen Mary’s Hospital in King George’s Medical University, Lucknow (click here). Report 25 May

25 May 2021

729. Bala Mounika developed Covid-19 at 28 weeks and required ventilation and delivery at KIMS Cuddles hospital in Hyderabad (click here). Both mother and baby recovered. Report 23 May

728. An unnamed women in Mandya, Karnataka, India, died from Covid-19 five days after giving birth at Mandya District Hospital (click here). Report 22 May

727. Nerissa Rego contracted Covid-19 while pregnant (click here). She recovered at home. The pregnancy is ongoing. Report 24 May

726. Fifty women with Covid-19 gave birth at Pt BD Sharma Post Graduate Institute of Medical Sciences (PGIMS) in Rohtak, India in April and May (click here). 250 such women have given birth since the start of the pandemic. 130 by Caesarean. The newborn babies were separated from their mothers. Report 25 May

20 May 2021

725. An unspecified number of women with Covid-19 gave birth at Holmes Regional Medical Center in Florida (click here). They were separated from their babies. Report 20 May

724. 29 women with Covid gave birth at the NOAH birth complex in Cebu city in the Philippines (click here). Report 20 May

723. An unnamed pregnant woman from Allalabad died from Covid-19 at the People’s Medical College in Bhopal on 5 May (click here). Her baby survived. Report 20 May.

722. An unnamed woman in the souhern Brazilian city of Tubarao received the Coronavac vaccine during pregnancy (click here). She gave birth in April. Report 20 May Vaccine in pregnancy news report

721. Szilvia Bedo-Nagy contracted Covid late in 2020 (click here). She gave birth by Caesarean in Budapest, and required ventilation, and treatment with an artificial lung, presumably ECMO. She recovered. Report 20 May

18 May 2021

720. Adriely Carneiro de Santan,a from Brazil, died from Covid-19 in September 2020, shortly after giving birth (click here). Report 7 May 2021

719. An unnamed woman in Nagpur, India, was seriously ill with Covid-19 ten days after giving birth (click here). She died the following day. Report 17 April

718. Shamili, a police inspector from Karnataka, India, contracted Covid19 at 7 months and died (click here). Report 18 May

16 May 2021

717. On April 20 a 38-week gestation, hour-old, baby at Akanksha Hospital and Research Institute (AHRI) in Anand, India, developed multisystem inflammatory syndrome in children (MIS-C) (click here). The mother tested negative but the baby had anti-Covid antibodies. The baby survived. Other similar cases are reported from SSG Hospital in Vadodara. Report 16 May

716. Sarladevi contracted Covid and gave birth at the ICU of Tilhar Medical College in India (click here). Two other unnamed women with Covid also gave birth in the ICU. One of their babies died. Report 15 May

15 May 2021

715. Chelsea Arnold got vaccinated while breast feeding her one-year-old daughter (click here). Report 11 May

714. Sruthy, a nurse in Dubai contracted covid while pregnant and suffered a miscarriage. Harsha Pushpan contracted Covid at 8 months, recovered and gave birth normally (click here). Report 12 May

713. Catharine Paules got vaccinated in pregnancy and gave birth normally (click here). Report 13 May Vaccine in pregnancy news report

712. An unnamed pregnant woman from Rio de Janeiro reportedly died from a haemorrhagic stroke following the AstraZeneca vaccine (click here). Report 12 May. Vaccine in pregnancy news report

711. Erika Loegering was vaccinated twice in pregnancy and gave birth to a healthy son (click here). Despite her husband and older son testing positive she remained negative. Report 14 May Vaccine in pregnancy news report

710. Jessica O’Connell received the COVID-19 vaccine while pregnant (click here). Report 11 May Vaccine in pregnancy news report

709. Dimple Arora Chawla died from Covid-19 at 7 months gestation (click here). Report 14 May

6 May 2021

708. NBC correspondent Jo Ling Kent got vaccinated on 1 April and gave birth in late April (click here). Report 5 May. Vaccine in pregnancy news report

707. Serena Torres contracted Covid-19 while pregnant and required 37 days of ECMO. On 20 Oct 2020, at 32 weeks, she gave birth by Caesarean at Westchester Medical Center in New York State (click here). She recovered. Report 6 May

706. An unnamed woman, who tested positive, gave birth at Teuk Thla Health Center in Sen Sok district, Phnom Penh, on 4 May (click here). Report 6 May

705. Dani Al-Mansouri, from Utah, got her 2nd dose of the Pfizer vaccine at 31 weeks. Yándary Chatwin, got her 1st dose of Moderna at 13 weeks (click here). Report 5 May. Vaccine in pregnancy news report

4 May 2021

704. The unnamed partner of Shyam Sundar tested positive for SARS-CoV-2 and has been isolated after giving birth at Government Rajindra Hospital in Patiala, India (click here). Report 3 May

703. Tanya August-Hanson a member of the Manx (Isle of Man) Legislative Council was vaccinated against covid at 39 weeks gestation (click here). She gave birth last weekend. Report 4 May Vaccine in pregnancy news report

702. This article reports the search for breast milk donors for the babies of two unnamed women who died of Covid-19 (click here). One mother died in Delhi last week, and the other in Lucknow recently. Report 4 May

701. By 4 May 2021, 1,001 SARS-CoV-2 infected mothers had given birth at Nair hospital in Mumbai (click here). They had 1,023 babies, including a set of triplets and 19 pairs of twins. There were 599 normal births and 402 caesareans. Report 4 May

700. An unnamed pregnant woman died from Covid-19 in Varaždin maternity hospital in Croatia (click here). Report 4 May. HT @DanielaDrandic Update 5 May. She was delivered by Caesarean. Baby’s birthweight 2,500g.

699. Mikaely Karoline Souza contracted Covid-19 at 7 months gestation, and died undelivered in the Emergency Care Unit in Sinop, in Matto Grosso, Brazil on 3 May (click here). Report 3 May

698. Maria Laura Prucoli, contracted Covid and was delivered by Caesarean at Saracuruna Hospital, in Duque de Caxias, in Baixa Fluminense, Brazil (click here). She died on 18 April. The baby tested positive but survived. Report 18 April

697. Letícia Aparecida Gomes from Maricá, Brazil, contracted Covid-19 while pregnant and spent a week in ICU. She recovered and the pregnancy is ongoing (click here). Report 4 May

3 May 2021

696. In Alberta, 85 to 95 unnamed pregnant women tested positive within one week (click here). On 30 April three COVID-19 pregnant patients were admitted to one hospital in Calgary. In the same week in Alberta two pregnant patients went to the ICU, and 22 visited the emergency room. Report 1 May

1 May 2021

695. Nair hospital, one of the largest treating pregnant women with Covid-19 in Mumbai has already recorded 26 maternal Covid deaths in 2021, compared with 12 between April and December 2020 (click here). Report 1 May

694. This opinion piece in the South China Morning Post includes the first newspaper report of a maternal death in China; an unnamed “pregnant woman from the rural area in Huanggang, Hubei province, who died of Covid-19 complications after spending more than a week in the intensive care unit at the Wuhan University South Central Hospital” (click here). The case is from early 2020. See also study 383 (click here) which also mentions a maternal death from Wuhan in the supplementary files. Report 1 May

693. The unnamed, five month pregnant, wife of Kolkata journalist, Sujit Nath, contracted Covid-19 on 10 April (click here). She was treated at home with steroids, oxygen saturation monitoring, and home oxygen. She recovered and the pregnancy is ongoing. Report 30 April

692. Christina Jones from South Wales contracted Covid-19 on February 18 (click here). She required nine days ventilation, during which her baby was delivered by Caesarean at 31 weeks, on 2 March. Both recovered. Report 1 May.

691. Laura Hix, from Tulsa, USA, contracted severe Covid-19 while pregnant (click here). She required ventilation and on 30 April, at 28 weeks, was delivered by Caesarean. Report 1 May

690. The unnamed wife of Rafael Córdova from Peru contracted Cobid-19 and gave birth to twins prematurely (click here). Both twins died. Report 29 April.

30 April 2021

689. Shaneen Robinson-Desjarlais from Winnipeg contracted Covid, six days after giving birth (click here). Her baby was also infected. Report 29 April.

29 April 2021

688. Hari Teja, a television actress from India, contracted Covid-19 in late pregnancy (click here). The baby was born by Caesarean on 5th April, not infected, but was isolated from her for a week. Report 29 April

687. Between January and April 2021 at least 433 pregnant, or post-partum women died from covid-19 in Brazil (click here). Report 28 April 2021

686. Four unnamed unvaccinated pregnant women with Covid-19 are currently in intensive care in Beaumont Hospital, Royal Oak, Michigan, USA (click here). In the same article a doctor reports that a small number (possibly only one) pregnant women have died from Covid-19 in Grand Rapids. Report 29 April

28 April 2021 HT Branka Firulovic and Christoph Brezinka for report 683

685. An unnamed woman with Covid-19 delivered twins at a coronavirus community health centre in Chandausi in Sambhal district of Uttar Pradesh on 27 April (click here). Report 28 April

684. Fatma Yıldız contracted Covid-19 in the second trimester of her pregnancy (click here). She was in a coma for 12 days, and required 3 weeks intensive care at Gaziantep University Hospital. The pregnancy is ongoing and she was discharged from hospital on 27 April. Report 27 April

683. An unnamed woman died from Covid-19 on 16 April two days after giving birth by Caesarean at the Clinical Center of Montenegro (KCCG) in Podgorica (click here). The report states that this is the first maternal death among 52 women with Kovid who gave birth in the previous four and a half months in Montenegro. Report 19 April

27 April 2021 HT Branka Firulovic and Christoph Brezinka for reports 675-679

682. Misbah, the wife of Ali Syed, from Saskatchewan, Canada, contracted Covid-19 during her pregnancy (click here). She gave birth safely, but her husband died of Covid-19. Report 26 April

681. Isabel Castillo was vaccinated while pregnant on 6 April, in Santiago, Chile (click here). Report 26 April. Vaccine in pregnancy news report

680. Theresa Potenza contracted Covid-19 in November 2020, at 34 weeks gestation (click here). She was nursed at home and gave birth safely at Ospedale Gemelli in Rome at about 38 weeks. Report 27 April

679. A newborn baby died of Covid-19 age 37 days, at Hagia Sophia hospital in Greece (click here, here or here). Reports 8 March and 20 April

678. An unnamed woman with Covid-19, from Trstenik, gave birth normally in Kraljevo Serbia (click here or here). The baby tested positive and died 10 days later from Corona infection. Report 19 April.

677. A unnamed 24-year-old pregnant woman died on 9 April in the University Clinical Center in Kosovo as a result of covid-19 (click here). The report also states that “Since the beginning of the pandemic, several pregnant women and midwives with kovid 19 have died in Kosovo”. Another unnamed 41 year old woman died in the same clinic on 23 March after giving birth at 31 weeks. Report 9 April

676. An unnamed pregnant woman died from Covid-19 died in Kosovo on 13 April (click here). Report 16 April

675. An unnamed Covid-positive pregnant woman died in Djakovica, Kosovo, on April 21.(click here). Report 21 April.

674. An unnamed woman died from Covid-19 on 26 April shortly after giving birth in Kanpur, India (click here). In Hindi. Report 26 April.

673. An unnamed woman in Kerala died from Covid-19 five days after giving birth (click here). In Malam. Report 27 April

672. An unnamed woman with Covid-19 gave birth safely in Malkangiri district headquarters hospital, in India, on 22 April (click here). Report 27 April

671. Prerna Shrestha got the Pfizer-mRNA vaccine in February when she was pregnant and later gave birth safely (click here). Report 26 April Vaccine in pregnancy news report

25 April 2021

670. Faiza Khan contracted Covid-19 shortly after giving birth in New Delhi (click here). Report 24 April

669. Cara Kirschner Estrada contracted Covid at seven months gestation and was delivered by Caesarean (click here). Her baby is doing well, but she is seriously ill on life support. Report 25 April

24 April 2021

668. Three unnamed pregnant women with Covid-19 are currently being treated in intensive care in Ireland (click here). Report 19 April

667. Yolanda Roberson, from Michigan, who had undergone a liver transplant in 2013 due to autoimmune hepatitis, and was also diabetic, contracted Covid-19 while pregnant on 24 December (click here). She receive monoclonal antibody treatment, and recovered. Report 22 April.

666. Alexa Forbes tested positive after preterm rupture of membranes at 34 weeks (click here). She later developed symptoms. Her baby was not infected. Report 21 April

665. Liz York got vaccinated during pregnancy, and had a Caesarean at 33 weeks (click here). Report 10 April. Vaccine in pregnancy news report

664. Alison Rose tested positive in pregnancy (click here). Report 23 April

22 April 2021

663. Dakota Lee Vest Wright contracted Covid-19 and gave birth by Caesarean at 30 weeks on 20 April (click here). She is currently on ECMO at the University of Alabama at Birmingham hospital. She had decided not to be vaccinated because she was pregnant. Report 21 April Vaccine in pregnancy news report

662. Cara Kirschner-Estrada contracted Covid-19 and gave birth by Caesarean at 28 weeks (click here). She is currently on ECMO at Royal Oak Beaumont hospital in Michigan. Report 22 April

21 April 2021

661. An unnamed woman from Gujarat, India, tested positive for SARS-CoV-2 during pregnancy and gave birth on 1 April (click here). Her baby contracted Covid-19 and died aged 15 days. Report 16 April

660. K Rohini contracted Covid-19 in pregnancy and died on 15 April in a Karimnagar private hospital in India (click here). Report 18 April

659. Dr Stephanie Chen got vaccinated while pregnant (click here). Report 26 March. Vaccine in pregnancy news report

658. Danika Jorgensen-Skakum contracted Covid-19 in December 2020, early in her pregnancy (click here). On 19 April, at 29 weeks gestation, she got a first dose of the Pfizer vaccine. Report 19 April. Vaccine in pregnancy news report

20 April 2021

657. An unnamed woman with severe Covid-19 gave birth normally at a special Covid ICU set up in an art gallery in Kalyan town of Maharashtra’s Thane district in India on 19 April (click here). Mother and baby are recovering. Report 20 April

656. An unnamed woman from Haryana, with Covid-19 gave birth to an infected child at Ayushman Bhav hospital in Haryana, India on 15 April (click here). Report 16 April.

655. A newborn baby from Kragujevac, Bosnia who was infected with Covid-19 died on 19 April, aged 9 days (click here). The mother’s Covid status and health was not reported. Report 19 April. HT Daniela Drandic @DanielaDrandic

18 April 2021

654. Rifat Sultana, a TV journalist in Dhaka, Bangladesh, contracted Covid-19 and was delivered by Caesarean on 15 April (click here). She died the following day. Report 17 April.

17 April 2021

653. An unnamed woman with Covid-19 was delivered by Caesarean at Ghai Hospital in Jalandhar, India on 14 April (click here). Report 17 April

652. An unnamed woman in Canada contracted Covid-19 and had to be delivered by Caesarean (click here). Another unnamed pregnant woman is currently on a ventilator in a Toronto ICU. Report 16 April.

16 April 2021

651. Six stillbirths and one miscarriage caused by Covid-19 in Ireland (click here). May include four from news report 603. Report 13 April.

650. A pregnant woman identified only as Megan contracted severe covid-19 towards the end of her pregnancy (click here). She required treatment in ICU but recovered. There are currently five pregnant women with Covid in one Toronto ICU and two in one McMaster ICU. Report 14 April

649. Two pregnant women in Hong Kong who had received BioNTech vaccine suffer miscarriages (click here). Report 14 April. Vaccine in pregnancy news report

15 April 2021 – two reports of maternal death from Bulgaria and five from Romania added. H/T Dr Branka Firulovic and Dr Christoph Brezinka

648. An unnamed pregnant woman died of Covid-19 at 20 weeks gestation, at Bega Maternity Hospital in Timisoara in March (click here). 14 other pregnant women infected with Covid-19, were in the same hospital, of whom three were in intensive care. Report 31 March

647. An unnamed 32-year old nurse from Buzäu with Covid-19 was delivered by Caesarean at Bucur Maternity Hospital in Bucarest (click here). She died a few days later. Report 5 January

646. Mirela Paiu contracted Covid-19 and was delivered by Caesarean at 35 weeks at Galati Hospital in Romania (click here) She died two days later. Report 14 December

645. An unnamed woman with Covid was delivered by caesarean at Timisioara hospital at 6 months gestation. The baby survived but the mother died two weeks later (click here). Report 9 December

644. An unnamed 34-year-old pregnant woman, with Covid, died at the “Bega” Maternity Hospital in Timişoara, Romania in March (click here). There are two other pregnant women with Covid in the same hospital. Report 31 March

643. A 32-years old pregnant woman in Bulgaria died of Covid on 5 March (click here). Report 5 March

642. An unnamed pregnant woman with coronavirus died at Blagoevgrad hospital in Bulgaria on 13 March (click here). There is another pregnant woman recovering from Covid in the same hospital. Report 13 March

13 April 2021

641. Liz Essley Whyte, a journalist, received the Pfizer vaccine in April while pregnant (click here). Report 12 April. Vaccine in pregnancy news report

640. Actor Sophie Rundle, BBC dramas Peaky Blinders and Gentleman Jack, contracted Covid-19 in December 2020. She recovered and gave birth over the Easter weekend (click here). Report 12 April

639. Liz Clim contracted Covid-19 while pregnant, and gave birth by Caesarean at 28 weeks at Elena Doamna Maternity Hospital in Romania (click here). Following the birth she was transferred to the Emergency Clinical Hospital “Saint Spiridon” where she died. Her baby tested negative but also died. Report 9 April.

638. Three unnamed women with Covid-19 gave birth naturally in a new unit at Makarios hospital in Cyprus (click here). Previously the hospital had insisted that all affected women had to deliver by Caesarean, due to problems with the hospital’s ventilation system. Report 12 April

9 April 2021

637. Hundreds of pregnant women were vaccinated against Covid-19 at a special clinic at UPMC Magee-Womens Hospital in Pittsburg, on 8 April (click here). Meg Graham and Breawna Taylor were named in the report. Report 9 April. Vaccine in pregnancy news report

636. Asha Vanshiv contracted Covid-19 and gave birth to twins by Caesarean on 5 April, at YCM Hospital in Pune, India (click here). She died the following day. The twins are doing fine. Report 9 April

635. Rhiannon Lane contracted Covid-19 and gave birth by Caesarean on March 21 at Texoma Medical Center in Texas (click here). Shortly afterwards her health deteriorated, she required ventilation and spent 18 days in ITU. She is recovering. report 9 April

7 April 2021

634. Charlene Jones contracted Covid-19 during her pregnancy and gave birth by Caesarean on 23rd December (click here). Two days post natally she required intubation and ventilation. She recovered. Report 7 April

633. An unnamed woman with severe Covid-19 gave birth at 29 weeks while intubated and ventillted at Attikon Hospital in Athens, Greece (click here). The date of the delivery is not reported. Report 7 April.

6 April 2021

632. Zeynep Aslı Kaplan received the CoronaVac vaccine (also known as Sinovac COVID-19) in the 29th and 33rd weeks of her pregnancy, and gave birth at 38 weeks (click here). Report 6 April. Vaccine in pregnancy news report

2 April 2021

631. Three unnamed women at Can Misses hospital in Ibiza have been vaccinated in pregnancy and one has given birth to a baby with antibodies (click here). Report 2nd April Vaccine in pregnancy news report

30 March 2021

631. Mbali Mbatha contracted Covid-19 and was delivered by caesarean at 30 weeks on 1 December at Netcare Milpark Hospital in Johannesburg (click here). She was treated with ventilation, ECMO and eventually a lung transplant. She and the baby recovered. Report 30 March.

630. Yumi Palmer contracted Covid-19 in March 2020, just before she gave birth (click here). Report 30 March 2021.

28 March 2021

629. An unnamed 21-year-old Jordanian women died of Covid-19, on 23 March, eight days after giving birth at Prince Hamzah hospital, Ru’a Nsour (click here). Report 28 March.

628. Ann-Marie Williams, from Cornwall, who requires parenteral feeding for a mystery illness, gave birth to twins in January 2021 and contracted Covid-19 soon afterwards (click here). She recovered. Report 27 March.

27 March 2021 (including update on reports 289 and 601)

627. Haley Saunders got the Moderna vaccine, with her second dose at 9 months gestation (click here). She gave birth Feb. 24 at Southwest Memorial Hospital in Colorado. Report 23 March. Vaccine in pregnancy news report

626. Dr Maggie Burke, from Bethesda, Maryland, received the Pfizer vaccine at 27 and 30 weeks gestation, and gave birth on 13 March (click here). The baby was healthy and had antibodies. Report 25 March. Vaccine in pregnancy news report

21 March 2021

625. Asarwa Civil Hospital, Ahmedebad, India has cared for 200 births to Covid-19 positive women (click here). They included Radihika Parihar, Hiral Shah, Ritu Yadav, and Asha Patel, all of whom delivered healthy babies. Report 21 March

624.  Louise Tranham from Margate contracted Covid-19 in November at 26 weeks gestation (click here). Her baby died in utero at 27 weeks and 5 days. Report 21 March.

623. Kim Murray, wife of tennis player Andy, tested positive late in her fourth pregnancy (click here). She gave birth normally in early March, and the baby is healthy. Report 21 March.

18 March 2021 (including update on report 548)

622. Nisa Celik received the Astra Zeneca vaccine at 11 weeks gestation (click here). She had short term side effects. The pregnancy is ongoing. Report 17 March. Vaccine in pregnancy news report

621. By October 31, 2020, about 1,835 Covid-positive pregnant women had given birth in the state of Kerala, India (click here). 245 of their babies had tested Covid positive. Report 18 March

620. Jennifer Pinedo contracted Covid-19 at 36 months [sic] gestation (click here). Note – presumably 36 weeks. She recovered and gave birth to a healthy daughter. Erin Arnst, from Fowlerville, got the vaccine at six months. Her pregnancy is ongoing. Report 18 March. Vaccine in pregnancy news report

17 March 2021

619. About 20% of women presenting in labour to Port Moresby General Hospital in Papua New Guinea have symptoms of Covid-19 (click here). Of them, about one-third (four to five women a day) test positive. Report 16 March

16 March 2021

618. Michelle Melton, got the Pfizer-BioNTech vaccine at 35 weeks gestation at Skippack Pharmacy in Schwenksville (click here). Report 16 March Vaccine in pregnancy news report

617. Shuruq Jubran from Jisr az-Zarqa in Israel contracted Covid-19 and was treated at Hadera’s Hillel Yaffe Medical Center (click here). She died on 15 March, three weeks after giving birth. Her sister, Amna Kahwaji, had died 10 days earlier, a week after giving birth, also from Covid-19. Report 16 March.

616. Since the beginning of February, three unnamed pregnant women aged 22, 27, and 32 years have died from Covid-19 in Tirana, Albania (click here). Another three pregnant women, one of whom is critically ill and intubated, are currently hospitalized with the disease. Report 15 March.

615. Nayeli Rodulfo-Zayas, a doctor from San Antonio, treating Covid-19 patients had the Pfizer Covid-19 vaccination in December, the 2nd dose in January, and gave birth to a healthy boy on 28 January (click here). Report 15 March. Vaccine in pregnancy news report

614. Carrie-Anne Osborne, from Hartlepool, UK, contracted Covid-19 at 33 weeks and gave birth on 29 December (click here). She spent four weeks in ITU but recovered. Report 16 March.

15 March 2021

613. Nair Hospital, Mumbai has cared for over 1,100 Covid-positive expectant mothers, of whom 764 have given birth and 45 babies have been infected (click here). The birth of Tanushri Bhanage is described in detail. Report 15 March

612. Alexia Khammanivong contracted Covid-19, at 30 weeks, required ventilation and ECMO, and gave birth by Caesarean (click here). Her baby died of complications of prematurity, but she recovered. Report 15 March.

14 March 2021

611. Arpana Dalvi, Prachi Kunal Salgia, and Ritika Khatri, all contracted Covid-19 while pregnant, and gave birth in 2020, in India (click here). Report 14 March

610. Three unnamed women with Covid-19 who required treatment with ECMO in Rabin Medical Center in Petah Tikvah are recovering (click here). The article also states that there are 41 pregnant or recently pregnant women hospitalised with Covid-19 in Israel. Report 13 March

13 March 2021

609. Yvett Camacho from Fontana in California, contracted Covid-19 at 30 weeks (click here). She was delivered by Caesarean and, from 21 to 31 January, was treated with ECMO at Cedars-Sinai Medical Center in Los Angeles. Mother and baby recovered. Report 12 March.

11 March 2021

608. Mel Wilson, from Harrisburg, Pennsylvania, got vaccinated at 28 weeks (click here). She is due in March. Report 11 March. Vaccine in pregnancy news report

607. Maidi Martínez from Cuba contracted severe Covid-19 and gave birth by Caesarean at 35 weeks at Manuel Fajardo Military Hospital (click here). Mother and baby recovered. Report 10 March

7 March 2021

606. Rachael Mutch tested positive for SARS-CoV-2 and gave birth at term at Ipswich Hospital on Feb 12 (click here). Report 6 March

6 March 2021

605. Mary Ann Brussels contracted Covid-19 at 34 weeks in April 2020 (click here). She gave birth by Caesarean at Long Island Jewish Medical Center, and later required ventilation. Both mother and baby recovered. Report 5 March

604. An unnamed women with Covid-19 gave birth on 6 March by Caesarean section at the General Hospital of Corfu (click here). Mother and baby are in good health. Report 6 March

4 March 2021

603. Four unnamed women with mild or moderate Covid-19 in the Republic of Ireland experienced a stillbirth in January and February 2021 (click here). Report 4 March.

602. Allison Goldfarb tested positive for Covid in late pregnancy and in January 2021 gave birth in a car on the way to hospital in New York (click here). Report 3 March.

601. Victoria Gallardo from Cypress, Texas, contracted Covid-19 about 11 days after giving birth (click here). She is now in a coma in an ITU in Texas. Report 4 March. Update 27 March (click here). She died on 16 March.

2 March 2021

600. An unnamed women with Covid-19, who had recently given birth, and was being cared for in the Covid care hospital at Lal Chowk, in Kalyan, near Mumbai, was allegedly sexually assaulted on 1st March (click here). Report 2 March

599. Witney Carson, a celebrity dancer, had Covid-19 when her son was born by 2nd stage Caesarean in January (click here). Report 1 March.

598. Ellie Wright from Walsall contracted Covid-19 at 30 weeks and gave birth by Caesarean on 12 January (click here). She required three weeks ventilation and remains in hospital. The baby has gone home. Report 1 March.

28 Feb 2021

597. After mentioning the woman in report 588, this report states that 50 pregnant are currently hospitalised in Israel with Covid-19 (click here). Report 27 February

596. An unnamed woman who had contracted Covid-19 at 25 weeks, experienced a stillbirth at 36 weeks (click here). She was cared for at Meir Medical Center, Kfar Saba, Israel. Report 27 February

27 Feb 2021

595. Joanna Jimenez contracted Covid-19 and gave birth on Feb. 13 (click here). She died a few days later. Report 27 February.

594. An unnamed pregnant woman from Bhopal, India, told CNN she had received the first injection Covaxin before being turned away for the second dose due to her pregnancy (click here). Report 26 February Vaccine in pregnancy news report

593. MaElena Barcenas from  Detroit contracted Covid-19 in March 2020 at 30 weeks and required delivery by Caesarean and 33 days ventilation.  Russell Powell, from Charleston, South Carolina, contracted Covid-19 at 30 weeks and went into preterm labour at 33 weeks. (Click here for their stories.) The story of report 293 is included. Report 26 February

25 Feb 2021

592. An unnamed woman had severe Covid-19 at 32 weeks, and was delivered by Caesarean in January (click here). Following ECMO treatment she is now in a coma in Leicester Royal Infirmary, her chance of survival is slim, and a judge has ruled that that her doctors can lawfully stop providing life-support treatment. Report 21 February.

21 Feb 2021

591. An unnamed woman with Covid-19 gave birth in an ambulance on her way to hospital in the northern Malappuram district of Kerala (click here). Mother and baby are doing well. This is said to be the third report of Covid positive women giving birth in an ambulance in Kerala. Report 21 February

590. Olivia Buxton, from West London, tested positive for Covid-19 at 36 weeks gestation (click here). She gave birth normally on Jan 24 at 39 weeks. Her baby Jude was healthy.  Report 21 February.

589. Catherine Mezzacappa, a doctor, got vaccinated while pregnant (click here). She registered with the CDC V-safe phone app. Report 19 February. Vaccine in pregnancy news report

588. Osnat Ben-Shitrit from Jerusalem contracted Covid-19 at 30 weeks gestation and died (click here). Her baby delivered by Caesarean died too. Report 21 February. She had not been vaccinated (click here). Update 23 February Vaccine in pregnancy news report

20 Feb 2021

587. Ashley Wadley, from Oregon, contracted mild Covid-19 at 31 weeks gestation (click here). She stayed home. Her baby was born via Caesaren 4 days later on Jan 15. He tested positive and died on 17 Jan. Report 19 February

17 Feb 2021

586. Dr. Jane Martin, got her COVID-19 vaccine while pregnant with her third child (click here). The baby was born healthy. Report 17 February. Vaccine in pregnancy news report

585. Olivia Hall had symptoms of Covid-19 early in the pandemic but was not tested. She gave birth by Caesarean in Southmead hospital, Bristol on 25 March (click here). Report 17 February

584. Three unnamed women with Covid-19 have given birth to stillborn babies in Assuta Hospital in Ashdod, Isreal, according to the head of infectious diseases there, Dr Tal Brosh (click here). Report 16 February

16 Feb 2021

583. Emma Bullen, from Tiverton, contracted Covid-19 at 39 weeks and gave birth by Caesarean at Royal Devon and Exeter Hospital (click here). Both recovered. Report 15 February

15 Feb 2021

582. Twelve pregnant women are reportedly critically ill with Covid-19 in Israel (click here). Details were given for two. One on a ventilator in Kaplan hospital in Rehovot, and another seriously ill at 13 weeks gestation in an unnamed hospital. Report 15 February.

581. Chaya Mehlman, Joelle Harari-Chadow, and another 250 pregnant women received Covid-19 vaccination at the Center for Health Education, Medicine and Dentistry, in Lakewood, New Jersey, between 12 and 14 February (click here). Report 15 February. Vaccine in pregnancy news report

13 Feb 2021

580. Bridget Klingenberg, from Covenant, contracted COVID-19 at 27 weeks gestation (click here). She is currently in ICU at the University of Michigan and the pregnancy is ongoing. Report 12 February.

579. Bat Sheva Baruch, from Jerusalem, Israel, contracted COVID-19 at 31 weeks gestation (click here). She required treatment in ICU and support with breathing, but the pregnancy continued and is ongoing. Report 12 February.

11 Feb 2021

578. Zarina Rose from Las Vegas contracted Covid-19 at 32 weeks gestation (click here). Labour was induced but she died shortly after birth. The baby survived. Report 11 February

9 Feb 2021

577. Two unnamed pregnant women are seriously ill with Covid-19 at Hillel Yaffe Medical Center, Israel (click here). One was delivered at 34 weeks and one at 37 weeks, both by Caesarean. Report 7 February.

576. Rose Jimmichen from Scunthorpe, UK, contracted severe Covid-19 in pregnancy (click here). She was delivered by Caesarean at 29 weeks. Report 2 February

575. Tori Howell from the Forest of Dean in Gloucestershire, UK, contracted Covid-19 at 22 weeks (click here). The pregnancy is ongoing. Report 5 February.

574. An unnamed 30 year old resident of Lakewod, New Jersey, contracted Covid-19 while pregnant (click here). Report 8 February.

7 Feb 2021

573. Rachel McCartney, from Aldershot, who was pregnant with twins, had two inconclusive Covid-19 tests and was induced at 34 weeks at Frimley Park Hospital, Surrey (click here). Report 7 February.

6 Feb 2021

572. Veronica Bernal from Arizona died of Covid-19 shortly after giving birth to twins (click here for 6 Feb google search on which she appears). No primary reports accessible in Europe due to data protection issues. Report 6 February. 10 Feb update. Click here for a report available in Europe.

571. Maggie Romano got vaccinated at 15 weeks gestation and Sarah Scherschel at 31 weeks (click here). Report 5 February. Vaccine in pregnancy news report

570. Paula Zion contracted severe Covid-19 at 17 weeks gestation, and required ventilation. She recovered and gave birth to a healthy boy on 4 February at the Royal Bolton Hospital (click here). Report 5 February.

569. Becky Regan, from Blyth, Northumberland died of Covid-19 on Feb 1st, shortly after giving birth by Caesarean at 31 weeks gestation (click here). Report 5 February

4 Feb 2021

568. Anthony Fauci says that about 10,000 pregnant women have received Covid-19 vaccinations in the USA and no “red flags” have been noted (click here). Report 1 February. Vaccine in pregnancy news report

3 Feb 2021

567. Christelle Berrington from Durban, South Africa, contracted Covid-19 at 35 weeks (click here). The baby delivered and she recovered. Report 25 January

1 Feb 2021

566. Maria Murillo, from Oklahoma City, contracted Covid-19 in July, at 25 weeks gestation (click here). The baby was delivered by Caesarean, and the mother required ventilation and a month in ITU. Both survived, although the baby remains in neonatal intensive care. Report 1 February. Update 11 July. The baby is still in intensive care (click here). It appears she cannot be weaned off the ventilator. Report 11 July

565. Anischa Morris, from Cape Town, contracted Covid-19 at 34 weeks in early December (click here). Her baby was delivered by Caesarean section at Groote Schuur Hospital, and went home on Dec 23rd. But Anischa’s condition deteriorated, and she died on 14 January. Report 1 February

564. Kelsey Townsend, from Madison, Wisconsin, contracted Covid-19 in October (click here). She gave birth on Nov 4th and required prolonged ventilation and ECMO at UW Health, University Hospital Wisconsin. At one point she was considered for a lung transplant, but this was not necessary. She left ICU mid January, and went home on 27 January. Report 1 February

563. Samantha Spicer, from Rushden, Northamptonshire, contracted Covid-19 at 12 weeks gestation (click here). The pregnancy is ongoing. Report 1 February.

562. Olympic gymnast Shawn Johnson, who is currently pregnant with her second baby, tested positive for COVID-19 early in her second pregnancy (click here). The baby is due in the summer. Report 1 February

30 Jan 2021

561. Kailtin Bolan a registered nurse at Fresenius, New York, got vaccinated against Covid-19 while pregnant (click here). Report 29 January. Vaccine in pregnancy news report

560. An unnamed pregnant woman is pictured receiving the Pfizer-BioNtech Covid-19 vaccine in Tel Aviv on January 23, 2021 (click here). Report 30 January. Vaccine in pregnancy news report

559. Farheen Raza, a radio personality from Flower Mound, Texas, contracted COVID-19 in April 2020. but did not fully recover (click here). In September she conceived and has continued to have post Covid symptoms through the first four months of her pregnancy. Report 30 January.

28 Jan 2021

558. Eva Gicain, from Basildon, contracted Covid-19 at 34 weeks gestation in late October (click here). She required ventilation, and ECMO for three weeks, but recovered. Report 28 January

557. Natalie Keller from Oklahoma contracted Covid-19 and was delivered by Caesarean (click here). Report 26 January

556. Reality TV star Lauren Goodger contracted Covid-19 in October, early in her pregnancy (click here). The pregnancy is continuing and she is due to give birth in July. Report 26 January

555. Visibly pregnant 34-year-old Narkis received her coronavirus vaccine in Tel Aviv, January 21, 2021 (click here). Report 27 January. Vaccine in pregnancy news report

554. Elsa Larkins contracted Covid-19 and required ventilation and preterm caesarean birth at Kingston Hospital, London on 5 Jan (click here). She remains in intensive care. Report 22 January. Update 1 February, mother & baby recovered (click here).

25 Jan 2021

553. Mandy Nguyen contracted Covid-19 at 32 weeks gestation and gave birth on 6 April 2020 by Caesarean section at the Royal London Hospital (click here). She required 3 weeks of ECMO support, but survived. Report 25 January

24 Jan 2021

552. Pregnant Houston city council member, Abbie Kamin received the Covid-19 vaccine recently (click here). The article also reports Stephanie Humbert, division manager of the health department’s nurse family partnership program as saying that about 17 pregnant women have also received the vaccine. Report 24 January. Vaccine in pregnancy news report

551. An unnamed 28-year-old woman from Dhamtari district gave birth to triplets in the All India Institute of Medical Sciences (AIIMS) Raipur, Chhattisgarh, India on 18 october 2020 (click here). Report 30 October.

23 Jan 2021

550. Ashley Bennett from South Carolina, died of Covid-19 on Jan 8, a week after giving birth by Caesarean to her 10th child (click here). Report 22 January.

549. Courtney Sewell from Oldham contracted coronavirus at 35 weeks and gave birth at St Mary’s Manchester (click here). Mother and baby are well. Report 23 January

20 Jan 2021

548. Jackie Dennis from Michigan contracted Covid-19 in November, and birth was induced on November 27th (click here). She was placed on a ventilator at Henry Ford Wyandotte Hospital on Dec. 5th and later transferred to another hospital where she required ECMO for a month. On 16 January she received a lung transplant. Report 19 January. Update 18 March (click here). She has recovered and been discharged home without oxygen. Update report 17 March.

547. Sameera Khan contracted Covid-19 in early January and required ventilation, and delivery by Caesarean, at the Royal London Hospital (click here). At the time of the report, she remained seriously ill. The baby was stable. Report 20 January

546. Leslie Shaw, from California, contracted Covid-19 in December 2020, and was delivered by Caesarean (click here). She died two weeks after birth. The baby survived. Report 18 January.

19 Jan 2021

545. Fatima Mohammed, from Bahrain, was infected early in her pregnancy (click here). No further details. Report 19 January

544. 750 pregnant women with Covid-19 have been cared for at the Institute of Obstetrics and Gynaecology and Government Hospital for Women and Children, Egmore, Chennai, India (click here). Report 19 January.

543. Katharine McMurray, from Oro Valley in Tucson, Arizona, contracted Covid-19 at the end of June 2020 and was delivered by Caesarean at 31 weeks (click here). Mother and baby survived. Report 18 January.

542. An unnamed woman with Covid-19, from Pazardzhik in Bulgaria, gave birth by Caesarean on 18 Jan (click here). Report 19 January

541. There are currently ten pregnant women hospitalised with severe Covid-19 in Israel (click here). They include four in Mayanei HaYeshua Medical Center in Bnei Brak, and one transferred from Laniado hospital in Netanya to Beilinson hospital in Petah Tikvah and ventilated. The Laniado Hospital is also treating another woman with COVID-19 who was placed on a ventilator after delivery (for details of this latter case click here). On 17 Jan a baby delivered to a mother with COVID-19 died at the Hadassah Medical Center in Jerusalem. Report 19 January. Some of the women are named here. Report 19 January

17 Jan 2021

540. Heli Prizant contracted Covid-19 in the third trimester (click here). She gave birth by Caesarean at Sheba Medical Centre in Israel and her baby was isolated from her. Both recovered. Report 16 January

14 Jan 2021

539. Taylor Kern from Mt. Washington, Kentucky, contracted Covid-19 at nine months gestation (click here). She required delivery by Caesarean, ventilation and 9 days treatment with ECMO. She recovered. Report 14 January

538. Nosipho Nkantini, from Eerste River in Cape Town, South Africa, contracted Covid-19 in early December (click here). She required ventilation and her baby was delivered by Caesarean on 17 December at 25 weeks. Both survived. Report 14 January.

537. Sam Hicks, from Bristol, UK, contracted Covid-19 in November and gave birth on 11 January (click here). Report 14 January.

536. Ashleigh Shirajudin, from Rhos-on-Sea, Wales, contracted Covid-19 at the end of her pregnancy with triplets (click here). She gave birth by Caesarean and all three babies were fine. Report 14 January.

535. Three doctors, Elizabeth Espinal at 20 weeks, Jackie Parchem gestation not reported, and Elaina Preston at 11-weeks received the Covid-19 vaccine (type not specified) while pregnant (click here). Report 13 January. Vaccine in pregnancy news report

534. Dr Tsion Firew contracted Covid-19 early in her pregnancy and recovered (click here).  On 24 December, at 27 weeks gestation she received the first dose of either the BioNTech/Pfizer or Moderna vaccine. 2nd dose 13 January. Report 13 January Vaccine in pregnancy news report

12 Jan 2021

533. Up to 8 January, 104 pregnant women had contracted Covid-19 in Cuba but none died (click here). There were also 17 postpartum cases, and two associated with ectopic pregnancy. The first report from Cuba. Source the Ministry of Public Health (MINSAP). Report 11 January.

532. Joy-Anna Duggar, a US TV personality, contracted Covid-19 at some stage in her pregnancy and gave birth to a healthy baby in August 2020 (click here). Report 11 January.

531. Of 192 births to Covid positive women at Sir Jamshedji Jeejeebhoy Hospital in Mumbai, India, no mothers have died and no babies tested positive (click here). This hospital has not previously reported cases. Report 12 Jan.

11 Jan 2021

530.  Veronica Guevara-Giron from Southland, Los Angeles, contracted Covid-19 at 34-weeks gestation (click here).  Despite ventilation, she died on 7 January. Her baby was delivered by Casearan at 35 weeks, and is OK. Report 10 January.

529. Steph Almond, from Manchester, tested positive for SARS-CoV-2 in labour (click here). She gave birth normally.  Report 10 June.

528. Revathi Pentapati was pregnant with twins when she contracted Covid-19 at about 36 weeks gestation (click here). She required ventilation and the twins were delivered by Caesarean at Milton Keynes Hospital in UK. Mother and babies are now recovering. She must be the previously unnamed woman in report 522. Report 11 January.

527. Aquarius Bunch contracted Covid-19 and was treated with ECMO at the University of Iowa hospitals in May 2020 (click here). This video clip (click here) shows her mobilising on ECMO. She recovered and was discharged on May 10th with the pregnancy ongoing. She gave birth to a healthy baby on 12 Aug. Report 14 August.

9 Jan 2021

526. María de Jesús Maroquín Hernández, from Ometepec, Guerrero, Mexico, contracted Covid-19 at 36 weeks gestation and was treated Acapulco General Hospital (click here). She had a girl and both recovered. The same report also describes Grecia Denise Espinosa who tested positive for the coronavirus at the National Institute for Perinatology in Mexico City, and gave birth to twins by cesarean. Again mother and babies recovered. Report 22 December.

525. Jennifer Chacon tested positive for SARS-CoV-2 on admission in labour early in January (click here). She gave birth at Dignity Health St. Bernadine Medical Center, San Bernadino, California. Mother and baby are doing well. Report 8 January

524. Tiere Scott White, from Omaha, contracted Covid-19 in late pregnancy in October (click here). She spent 30 days anaesthetised, and presumably ventilated. Her baby was delivered at 32 weeks. Both recovered. Report 8 January

523. Gemma Robinson from Hereford, UK, tested positive for SARS-CoV-2 in labour on 20 December (click here). Her and the baby were fine. Report 9 January.

522. An unnamed 36 year old woman with twins contracted severe Covid-19 and required ventilation and delivery by Ceasarean at Milton Keynes Hospital in early January (click here). The same report describes Daniyal Rizvi, who contracted Covid-19 and required critical care, but not ventilation at 13 weeks gestation. Her pregnancy is ongoing. Report 8 January

7 Jan 2021

521. Laura Eames, from Hull, East Yorkshire, was asymptomatic but tested positive for SARS-CoV-2 the day before her elective Caesarean (click here). Report 30 December.

520. Asley Gomez, from Van Nuys, Los Angeles, contracted Covid-19 and was delivered by Caesarean at Kaiser Woodland Hills hospital in December, but died soon afterwards (click here). Report 7 Jan

6 Jan 2021

319. Kaylee Gabak contracted Covid-19 on Christmas day and gave birth the next (click here). On 29 December she required ventilation and ECMO. Both are ongoing. Report 5 January.

318. Helen McEntee, Justice minister in the Republic of Ireland, who had announced her pregnancy on December 5th, tested positive for SARS-CoV-2 in early January (click here). Her pregnancy is ongoing. Report 6 January

317. Rachel Arfin contracted Covid-19 at 35 weeks and was was admitted to the ICU in University College London (click here). Her pregnancy is ongoing. Two other unnamed pregnant women are in the ICU in the same hospital. Report 6 January

5 Jan 2021

316. Safna, wife of Zulfikar Ali, from Thrissur, Kerala, India, contracted Covid-19 at term and gave birth by caesarean (click here). She recovered and the baby was not infected. Report 5 January.

315. Mackenzie Eagle Road, from McAlester, Oklahoma, USA, contracted Covid-19 at term (click here). She gave birth normally and recovered. The baby tested negative. Report 5 January.

314. JoEllen Engelbart, a lawyer from Missouri, USA, contracted Covid-19 and gave birth 3 months prematurely on 29th Dec (click here). She died four days later. The baby survived. Report 4 Janurary.

4 Jan 2021

313. Silatik Qavvik, from Sanikiluaq, Canada, contracted Covid-19 while pregnant and gave birth by Caesarean in November (click here). She died about a month later of complications of the disease. Her baby “is fine”. Report 3 January.

312. Beth Olliver from Barrow-in-Furness, UK, contracted Covid-19 at 16 weeks gestation and gave birth by Caesarean at 24 weeks due to obstetric complications, preterm rupture of membranes (click here). She and her premature baby survived. Report 4 January.

3 Jan 2020

311. Jennifer McWilliams, who had recently tested positive for SARS-CoV-2 gave birth at the National Maternity Hospital in Dublin, Ireland, on 1 January (click here). Report 2 Jan.

310. Iqra, wife of Ali Muhammad, who had Covid-19, gave birth by Caesarean in Hyderabad, India, on 2 January (click here). Report 3 Jan.

309. Emi Maganja from Croatia, contracted severe Covid-19 and gave birth on 14 December (click here). The baby survived but she died on 31st December. Report 1 Jan.

1 Jan 2020

308. An unnamed pregnant nurse in Tulsa, Oklahoma, recovered from Covid and her pregnancy was continuing (click here). Report 31 December.

307. Sukanya Gawda, from Mumbai, India, was asymptomatic, but tested positive for SARS-CoV-2 at term, and gave birth to a healthy boy in Nair hospital on May 12 (click here). Report 1 January.

306. An unnamed pregnant women with Covid-19 is being cared for in intensive care at London’s Whittington Hospital (click here). Report 31 December.

305. Keira Sanded, from Newhaven, East Sussex, UK, contracted Covid-19 at 21 weeks gestation (click here). The pregnancy is ongoing. Report 31 December.

304. Susie Espinoza, from Memphis, USA, contracted Covid-19 at 27 weeks gestation in May 2020, and gave birth by Caesarean while on a ventilator (click here or here). She and the baby recovered. Report 31 December.

303. Hilda Cruz Perez from Ohio, USA, contracted Covid-19 at and gave birth to a healthy boy by Caesarean (click here). After the birth her condition deteriorated, and she is currently ventilated and being treated with ECMO at Promedica Toledo hospital. Report 28 December.

31 December

302. Mariam Muhammad (a pseudonym), from Garowe, Puntland, Somalia contracted Covid-19 at eight-months gestation at the beginning of November 2020 (click here). She recovered and gave birth at term. The report describes ten other SARS-CoV-2 positive pregnant or postnatal women, and 20 suspected cases. Report 30 December.

301. Mehpara Navqi, from Bradford, UK, contracted Covid-19 at the start of October, at 7 months gestation (click here). She required nine days ventilation, and her baby was delivered prematurely by Caesarean. Both survived. Report 31 December.

28 December

300. Cindy Zepeda from California, contracted Covid-19 while pregnant and died in July (click here). The baby also died. Report 28 December.

299. Grace Victory, a UK social media personality, contracted Covid-19, as a result of which her baby had to be delivered early (click here). Her condition deteriorated and at the time of writing she had been placed in an induced coma. Report 28 December.

27 December

298. Sasha Jackson, from Birmingham, Alabama, contracted Covid-19 in July and gave birth prematurely (click here). Both mother and baby survived. Report 25 December.

297. Monique Jones, from Missouri USA, contracted Covid-19 at 5 months gestation (click here). She required prolonged ventilation, and her baby was born prematurely, but both survived. Report 27 December.

24 December

296. This newspaper report (in French) includes mention of 15 ectopic pregnancies & 34 maternal deaths in women with Covid-19, which have not previously been reported (click here). The maternal deaths are from the Indian “PregCovid Registry”. Denominator not stated, but rate reported as 1.1%. Report 21 December

23 December

295. Sara Roby, from Louisville, Kentucky, tested positive for SARS-CoV-2 during labour (click here). She was asymptomatic and gave birth normally. Her baby tested positive. Although reportedly also asymptomatic, the baby was retained in hospital. Report 23 December.

294. Alexandra Abrill, from Canada, contracted Covid-19 in December, near term (click here). She gave birth soon after, and the baby tested negative. Report 19 December

293. Vanessa Gonzalez, from Whittier in California, contracted Covid-19 in November, and gave birth shortly after (click here). The baby survived, but her condition deterioriated and she died on December 14. Report 23 December.

292. Cecilia Duran, a midwife in New York, contracted Covid-19 in March at 10 weeks gestation (click here). She recovered and had a healthy baby. Report 23 December.

291b. Tori Wiley, a nurse from Georgia, USA, contracted Covid-19 early in pregnancy, recovered, and gave birth normally at term to a healthy boy (click here). Report 23 December.

22 December

291a. Vasilisa Frolova, Ukrainian TV and radio host, tested positive for SARS-CoV-2 late in her pregnancy (click here). Report 22 December.

14 December

290. Nicole Keane, from Lexington Kentucky, tested negative for SARS-CoV-2 when her husband had symptoms and tested positive (click here). She was due in December, but on October 26, her baby was delivered by emergency Caesarean. The baby suffered brain damage. Her husband died of Covid-19 a short time after the birth. Report 14 December.

289. Princess Sophia of Sweden is pregnant and due in late March/early April (click here). It had previously been reported that she tested positive for SARS-CoV-2 on 24 November (click here). This would suggest she was about 20 weeks gestation when she tested positive. Report 14 December. Update 5 Jan. This report (click here) confirms that the had SARS-CoV-2 during the pregnancy and has recovered. Update 27 March (click here). She gave birth to a healthy baby on 26 March.

288. Kate Glaser from Buffalo, New York, and Erica Evert, from northern Virginia both contracted Covid-19 in late pregnancy (click here). Glaser’s route of delivery was not reported. Evert had a Caesarean. Both babies tested negative. Report 14 December

13 December

287. Dalia Gabriela Sosa Atondo, an obstetrician in Culiacán, Mexico contracted Covid-19 at 30 weeks gestation (click here). The baby survived, but she died on 21 August. Report 22 August.

10 December

286. Tawauna Averette from Ohio contracted Covid-19, and was delivered by Caesarean, but died on 14 November (click here). The baby was healthy. Report 10 December.

9 December

285. A woman named only as D, age 22, contracted Covid-19 and gave birth normally at FL Tobing Sibolga Hospital in North Sumatra on 11 November (click here). Report 15 November.

284. Eva Ahmed, age 28, from Wednesbury, in the West Midlands, UK, contracted Covid-19 and gave birth by Caesarean, on November 16 at 28 weeks (click here). After the birth she required ventilation but recovered. Report 2 December.

283. Svetlana Sorochinskaya, age 36, from St Petersburg, Russia, contracted Covid-19 and required ventilation (click here). She gave birth at 34 weeks and died shortly afterwards. Report 1st December.

282. Jasmine Logan from Detroit was pregnant with twins when she contracted Covid-19 (click here). Labour was induced, but her condition deteriorated, and she required treatment with ECMO at Detroit Medical Center. She recovered, but at the time of writing is still in hospital. Report 8 December.

281. None of the 62 pregnant women from Pune, India, who came into contact between April 6 to 8th with an ultrasonographer who had later tested positive, had shown symptoms by April 16th (click here). Report 16 April.

280. According to this newspaper report 1,089 pregnant women in Illinois have had COVID-19, and five have died (click here). The Illinois Department of Public Health is cited as the source. The five presumably include S276, S277 & S278 below. Report 2 July

279. An unnamed woman from Chicago contracted Covid-19 at 25 weeks (click here). She was cared for at St. Anthony Hospital in Little Village. She was later diagnosed with pre-eclampsia when she delivered in June but mother and baby are reported to be doing well. Report 2 July.

278. Unique Clay, from Chicago, died of Covid-19 on May 7th, five days after giving birth (click here). Report 9th May.

277. A 31-year-old woman, believed to be Lolita Davis, died of Covid-19 on May 15th, at Roseland Community Hospital in Chicago (click here). Report 3rd July.

276. Eli Solano died of Covid-19 on April 23rd, at Loyola University Medical Center, in Chicago, days after giving birth (click here). Her baby is doing well. Report 25th April.

5 December

275. Erika Becerra contracted Covid19 at 8 months gestation. She gave birth to her son Diego Antonio Becerra normally after induced labour on November 15, in Detroit. Her condition deteriorated and she died on 4 December (click here). Report 4 December.

274. An unnamed obstetrician died from Covid-19 in Lagos University Teaching Hospital, Lagos, Nigeria, in April 2020 (click here). He had reportedly been infected in his private clinic. Report 15 April.

4 December

273. Celma Castro from Brazil contracted Covid 19 at 7 months gestation (click here or here). She was delivered by Caesarean on May 22nd, but died on June 7th. Her daughter survived. Report 3rd December.

272b. Vitebsk Oblast Maternity Hospital in Belarus is currently treating 45 women with the coronavirus infection of whom 25 have already given birth (click here). All babies are healthy. There are reported to be 600 pregnant women with coronavirus in the country. Report 4th December.

272a. Dönüş Kılınç, from Istanbul, Turkey, contracted Covid-19 near to term (click here). She died in childbirth after allegedly being turned away by three hospitals because of her Covid status. The baby survived. Report 3rd December.

1 December

271. Carolina [surname not given], from San Juan del Río gave birth to twins by Caesarean at 33 weeks at Regional General Hospital number 2, in Querétaro, Mexico (click here). The date of the birth was not stated. Report 27 November.

270. Greer Gehler from Anchorage, Alaska, contracted Covid-19 at 20 weeks gestation (click here). The pregnancy is ongoing. Report 27 November.

269. Of 133 maternal deaths in Mumbai between April and October, 29 were directly caused by Covid-19, and a further 24 women who died from other causes had tested positive (click here). At BYL Nair Hospital 8/740 Covid positive women died. Sion Hospital had 14 maternal deaths out of 400 covid positive women. Report 28 November

268. Ashley Duque from Clairemont, San Diego contracted Covid-19 at 17 weeks gestation in March (click here). She required ventilation but recovered and gave birth on August 25th. Report 27 November Previously reported NR 71

267. Jessenia Hernandez from Loxahatchee, Florida contracted severe Covid-19 in October (click here). She was delivered by Caesarean at Palms West Hospital and then transferred to JFK Medical Center for ventilation. She recovered. Report 30 November.

266. Celine Ng-Chan from Singapore contracted Covid-19 in March and gave birth on 7 November (click here). Report 29 November

26 November

265. Sara Gutierrez from Texas contracted Covid-19 at 20 weeks gestation (click here). Report 25 November.

264. Kelly Macfarlane from Nashville, Tennessee, is 33 weeks gestation, the pregnancy is complicated by vasa previa, and she has tested positive for SARS-CoV-2 (click here). A Caesarean birth is planned for next week. Report 26 November.

24 November update

263. Two unnamed Sanömas women, had Covid-19 and their babies died (click here). It is not clear if the mothers were infected in pregnancy or how old the babies were. The women were part of the Yanomami ethnic group, from the village of Auaris, in the Brazilian state of Roraima. Report 24 November.

262. Donna Molina contracted Covid-19 in March at 30 weeks. She required 11 days ventilation, and delivery by Caesarean section at Hackensack University Medical Center in New Jersey (click here). The article also reports Kate Glaser, from upstate New York who contracted Covid-19 at term and delivered normally. Report 21 November.

261. Emily Brown from Tennessee, USA, contracted Covid-19 at 31 weeks in September. She required 20 days ventilation at Erlanger Hospital in McMinn county, during which she was delivered by Caesarean section on September 24 (click here). Report 24 November.

260. In Begaluru, Karnakata, India, 7/300 babies born to women with Covid-19 in Vani Vilas hospital, tested positive. In Gosha hospital, the rate was 15/168, at the Motherhood hospital, 2/35, at Fortis La Femme 1/45, and at Apollo hospital 0/6 (click here). Report 23 November.

19 November update

259. An unnamed woman from Dallas died from Covid-19 on 18 November, shortly after gving birth (click here). Report 18 November

18 November update

258. Gabby Manoz contracted Covid-19 in August and required both ventilation and ECMO at Community Regional Medical Center in Fresno, California, USA (click here). She was delivered at 32 weeks on September 11. Both mother and baby survived. Report 17 November.

17 November update

257. A woman identified only as Ewelina contracted Covid-19 and required both ventilation and ECMO (click here). The baby named Amelka was delivered via caesarean section at 27 weeks early in November at the University Clinical Hospital in Wroclaw, Poland. The mother is now off the ECMO, and no longer ventilated. The baby is recovering. Report 17 November.

256. Perpetual Uke, a rheumatology consultant at Birmingham City Hospital, in the UK, who was pregnant with twins, contracted Covid-19 in March (click here). She required ventilation, and on  April 10 at 26 weeks, delivery by Caesarean. Both her and the twins survived. Report 17 November.

15 November update

255. An unnamed woman (husband Abdul Aziz Bhat) who had tested positive for SARS-CoV-2 gave birth outside the Community Health Center Hajin, the designated Covid-19 Hospital in Bandipora, Jammu & Kashmir, India (click here). Report 15 November.

14 November update

254. Gillian McIntosh contracted severe Covid-19 and gave birth by Caesarean in Abbotsford Hospital, British Columbia, Canada in early November at 38 weeks (click here). She remains on a ventilator. Her baby boy is fine. Report 13 November. Update 31 December. She recovered (click here).

253. Amelia Cortez from Idaho, USA, contracted Covid-19 in May at about 36 weeks gestation. She gave birth soon after but her condition deteriorated and she required ventilation. She survived but six months later still requires respiratory support via an oxygen tank (click here). Report 14 November.

13 November update

252. Madeleine Surges from Duluth, Minnesota, contracted COVID-19 at 38 weeks gestation (click here). The birth is awaited. Report 12 November.

11 November update

251. According to this report about one hundred pregnant women have been infected with the coronavirus in the Helsinki and Uusimaa Hospital District, in Finland, since the pandemic began (click here). Report 10 November.

250. Lissy Yaya contracted Covid-19 at about 28 weeks and gave birth at about the same gestation to baby Jorgito in mid June, during the peak of the pandemic in Peru. Jorgito also tested positive but eventually recovered (click here). Report 11 November.

249. The stories of Blanca Rodriguez R215 below, and Monica Ramirez R242 below, are told in more detail (click here). According to the report another 46 unnamed pregnant women with Covid-19 have also been cared for at Loma Linda University Medical Center, of whom a quarter needed respiratory support. Report 10 November.

7 November update

248. Jessi Jenson age 24 contracted Covid-19 and on Oct. 28 gave birth by caesarean at term (click here). The baby was healthy but a few days later the mother became seriously ill and required ventilation and later transfer to Intermountain Medical Center in Murray, Utah, for ECMO treatment where at the time of writing she remains. Report 6 November.

247. An unnamed 34 year old woman with Covid-19 died on 6 November in Magadan infectious diseases hospital №2 in Magadan, Russia (click here). The baby, born prematurely by caesarean, survived. Report 7 November

3 November update

246. Sharlene Gillies from Birmingham, UK, contracted Covid-19 at 12 weeks (click here). She recovered and on Sept 24th, at 37 weeks, was delivered by Caesarean hysterectomy. The hysterectomy had been planned to treat co-existing cervical cancer. Report 2 November

245. This BBC news report states that between April and June 2020 there were 40 intrapartum stillbirths in England compared with 24 in the same period in 2019 (click here). Report 2 November.

27 October update

244. An unnamed woman tested positive for SARS-CoV-2 and gave birth at San Jorge de Huesca University Hospital in Aragon, Spain (click here). The baby also tested positive. Report 26 October.

243. Sadie Robinson, an American TV actress (Duck Dynasty) contracted Covid-19 early in pregnancy and recovered (click here). The pregnancy is ongoing. Report 26 October.

25 October update

242. Monica Ramirez contracted Covid-19 at 30 weeks (click here). She delivered by Caesarean and was on a ventilator for 3 weeks. She and her baby survived. She had been admitted to Corona Regional Medical Center in San Bernardino County, California in July, and later transfereed to Loma Linda University Medical Center. 48 pregnant women with Covid-19 have been cared for at the latter hospital. Report 24 October.

18 October update

241. Chava Leah bas Esther is seriously ill with Covid-19 in Ichilov Hospital in Tel Aviv (click here). Two weeks following Caesarean birth she remains on a ventilator & ECMO. The baby survived. Report 12 October.

240. Nuha Abu Siam died of COVID-19 on October 8, one month after she gave birth by Caesarean at Soroka Medical Center in Beersheba (click here). She had been treated with ECMO. The baby was unaffected. Report 12 October.

239. This Reuters report suggests that 80% of pregnant women in Bolivia are testing positive for SARS-CoV-2 (click here). Although I’m unaware of any different figures, this seems unlikely. Report 12 October.

238. Emily Donovan contracted Covid-19 and gave birth at 37 weeks at NorthBay Medical Center in Fairfield California, in July (click here). Mother and baby were fine. Report 15 October.

237. Heather Stocks gave birth in August at Diana, Princess of Wales Hospital in Grimsby, UK, after a false positive SARS-CoV-2 test (click here). Report 15 October.

236. Nahid Khan, and about 700 other women with Covid-19, have given birth at Nair hospital in Mumbai, india (click here). She and her baby survived. But eight other women and their babies died. Report 16 October.

235. An unnamed woman with Covid-19 at 23 weeks gestation appealed to the Bombay High Court to be allowed a pregnancy termination (click here). Report 14 October.

6 October update

234. Asfia Samreen contracted severe Covid-19 at 24 weeks gestation and required prolonged ventilation in Abu Dhabi (click here). She recovered and later gave birth to a healthy baby. Report 6 October.

5 October update

233. Pooja Charaniya contracted severe Covid-19 at 23 weeks gestation (click here). She spent 13 days on a ventilator at Texas Health Harris Methodist Hospital Fort Worth, Texas, USA and recovered. On July 22nd at 36 weeks she gave birth to Zayd who is healthy and Covid free. Report 30 September.

232. An unnamed mother infected with SARS-CoV-2 gave birth in the Skane region, in the south of Sweden to a baby who was also infected with SARS-CoV-2 (click here). Report 19 August.

29 September update

231. Thirty four pregnant women with Covid-19 have given birth in Mohali Civil Hospital, Sahibzada Ajit Singh Nagar, India (click here). Report 17 September.

230. Three hundred & seventeen women with SARS-CoV-2 have given birth at Lok Nayak Jai Prakash Narayan (LNJP), the biggest Covid-19 hospital in Delhi, India (click here). 143 were by Caesarean. Only 3 or 4 newborns were infected. Report 28 September.

27 September update

229. Santosh University Hospital, Ghaziabad, India has treated about 50 women with Covid-19 in pregnancy (click here). Some details are given about three infected women with pseudonyms who were delivered by Caesarean at term, and one who had birth induced at 28 weeks gestation. Report 21 September.

26 September update

228. An unnamed pregnant doctor from Indore, India, is reported to have developed Covid-19 twice during her pregnancy (click here). She first tested positive on June 19 and recovered. She tested positive again on September 19. She has mild disease, is being treated at home and the pregnancy is ongoing. Report 21 September.

227. Dr Pratiksha Waldekar (age 32), a pathologist from Amravati, died of Covid-19 at a private hospital in Nagpur, India,on September 20th (click here). She was 7 months pregnant. Her baby had died five days earlier. Report 22 September

226. Mrs Celine Ng-Chan contracted Covid-19 at 10 weeks gestation (click here). The pregnancy continued and she is due to give birth next month in Singapore. Report 26 September

14 September update

225. Sarah Curtis from Distington, Cumbria, UK, contracted Covid-19 shortly before giving birth to twins at 30 weeks (click here and here). Both babies were infected but survived. The pregnancy had been complicated by twin-to-twin tranfusion syndrome, and treated with laser ablation of the placental vessels.  Report 14 September.

13 September update

224. An unnamed woman tested positive and gave birth at 36 weeks in Taipei, Taiwan (click here). The baby tested negative. Report 12 September.

223. An unnamed woman with conflicting SARS-CoV-2 test results gave birth in a private hospital in Mohali, a suburb of Chandigarh, India (click here). Report 13 September.

9 September update

222. Ke’Lin Dillard, age 29, from Baton Rouge Louisiana, contracted Covid-19 and was delivered by Caesarean section in late July (click here). The baby tested negative and survived, but the mother remained on a ventilator and died on August 17. Report 7 Sept

221. An unnamed 23-year-old pregnant woman, with Covid-19 and other complications gave birth by Caesarean section at Government Rajaji Hospital (GRH) in Madurai, India, on August 11th (click here). Her age and clinical details differ from the woman in report 210. Report 8 Sept.

220. Maike Zwalf, from Queensland Australia, a transgender man, who also had cystic fibrosis, contracted Covid-19 at term and gave birth normally (click here). Report 8 Sept.

219. Patricia Alvarez from Baytown, near Houston, Texas, contracted Covid-19 in pregnancy, self-isolated at home and gave birth normally at term (click here). Report 9 Sept.

1 September update

218. An unnamed woman with Covid-19 gave birth at Victoria Hospital in Bangaluru, Karnataka, India on 26 August (click here). The baby died. Report 27 August.

217. An unnamed 39-year-old woman with Covid-19, from Lucban town in Quezon province in the Philippines, gave birth at the government run Quezon Medical Center (QMC) in Lucena city on 25 August (click here). The birth was normal. According to Dr. Belen Garana, head OB-GYN at QMC there has been a rise in pregnant women testing positive over the prevuious two weeks. Most were asymptomatic. Report 28 August.

216. Paropakar Maternity and Women’s Hospital in Kathmandu, Nepal, is opening an isolation facility with 200 beds for suspected and confirmed cases of Covid-19 (click here). So far 100 women have been suspected and one tested positive.. Report 25 August.

215. Blanca Rodriguez contracted Covid-19 at 28 weeks gestation (click here). She required prolonged ventilation, and her baby was delivered by C-section at Loma Linda University Medical Center in California. Both survived. Report 28 August.

214. In Los Angeles County 1,200 pregnant women have tested positive for the virus and two have died. Of 193 babies tested, eight were positive (click here). Report 26 August.

213. In the Indian state of Meghalaya, 877 babies and 61 pregnant women died over the four month COVID-19 pandemic (click here). Only 10 people in the state had died due to COVID-19 directly. According to Director of Health Services, Dr Aman War the maternal and perinatal mortality rate is a sharp rise above normal, largely due to women avoiding normal care and dying of other causes. Report 29 August.

212. Camila Graciano, from Anapolis, in the central Brazilian state of Goias, contracted Covid-19 at 32 weeks gestation (click here). Birth was induced, but she died. The baby survived. Report 26 August.

21 August update

211. An unnamed woman died from Covid-19 on 20th August, seven days after giving birth in Olongapo City in the Philippines (click here). Report 21 August.

20 August update

210. An unnamed woman with surgically corrected mitral valve disease and Covid-19 gave birth at the Rajaji Hospital in Madurai, India on August 13 (click here). Report 20 August.

209. A one-day-old baby born on August 16, at Assam Medical College & Hospital (AMCH) in Dibrugarh, India, tested positive for SARS-CoV-2 (click here). His mother was also positive, but it is not clear whether her test was during or after the pregnancy. Report 20 August.

19 August update

208. Belma Soljanin, age 37, died from Covid-19, 3 days after giving birth at Podhrastovi hospital in Sarajevo. She was head of the institute for mother and child. The baby tested negative and has no symptoms (click here). Report 10 August.  HT Dr Branka Firulovic

18 August update

207. About 28 women have tested positive for SARS-CoV-2 at some point in the pregnancy among those cared for at the National Maternity Hospital in Holles Street, Dublin (click here). Report 17 August.

206. Out of 170 Covid-19 births at Parklands Hospital Dallas, five babies tested positive (click here).  Among them, 28-year-old Yuri Matamoros was seriously ill. She recovered and gave birth to a son Jesus, who tested negative. Note the minor inconsistency with report 200. Report 17 August.

17 August update

205. An unnamed 37-year-old woman, with asymptomatic SARS-CoV-2 gave birth by Caesarean at 47 weeks gestation to a healthy boy at the “Attikon” General Hospital in Athens on 16 August. The baby weighed 2,630g, was in excellent health and was isolated (click here). Report 16 August.

16 August update

204. Eighty eight pregnant women with Covid-19 have delivered in the Indian State of Odisha, of whom 32 gave birth in a dedicated Covid hospital in Ganjam, and 15 in the city of Blasore (click here). All mothers recovered. One baby was infected. Report 15 August.

15 August update

203. Zully, from Stamford Connecticut, contracted severe Covid-19 in April at 8 months gestation. She required ventilation, but both her and the baby survived (click here). Report 11 August.

202. María Alvarez age 24 had SARS-CoV-2 while pregnant but was asymptomatic. She gave birth on July 29th at Peru’s National Perinatal and Maternal Institute, in Lima (click here). Mother & baby were fine. According to the report over 2,000 pregnant women with SARS-CoV-2 gave birth in that hospital between April and the start of August. 120 newborns were reported to have tested positive. Report 12 August.

14 August update

201.  Only one unnamed pregnant woman was diagnosed with Covid-19 in Buenos Aires, Argentina between March 20 and May 5th. She gave birth at Sardá Maternity Hospital. Mother & baby were discharged on April 29 (click here). Over the same period there were 2,200 deliveries in the the 33 public hospitals in Buenos Aires. Report 5th May.

13 August update

200. Wendy Figueroa contracted Covid-19 at 34 weeks and gave birth vaginally at Parkland Hospital in Texas (click here). Her baby Alexa was isolated and tested positive. The case was reported in Study 186 here. This newspaper report also notes that six babies have tested positive at Parkland Hospital out of 128 mothers with SARS-CoV-2 at some point during their pregnancy. Report 13 August.

12 August update (Thank you to Dr Christoph Brezinke & Dr Branka Firulovic for alerting me to reports 195-199 from Serbia and Romania)

199. An unnamed 31-year-old woman with Covid-19 died at 22 weeks gestation in Baia Mare hospital on 30 July (click here). The same day a 39-year-old with Covid-19 died at 28 weeks gestation during ambulance transfer between Arad and Timisioara. Report 30 July.

198. On August 8th an unnamed 33-year-old woman with Covid-19 died at 25 weeks gestation in Alba Iulia hopsital, Romania (click here). Report 8 August.

197. This report (click here) describes the two patients below (R195 & R196), and mentions a further pregnant woman from Vranje who was admitted to the Nis Clinical Center on July 3rd with symptoms of the corona virus, but testing negative, who has been on artificial ventilation since July 18. Report 29 July.

196. On 28 July 2020 an unnamed 34-year-old woman with severe Covid-19 pneumonia died after cesarean at 26 weeks gestation in Nis hospital, Serbia (click here). The baby is in neonatal intensive care. Report 28 July.

195. On 21 July 2020 an unnamed 27-year-old woman died from Covid-19 (click here). Her baby had been stillborn the previous day. Both were cared for at Nis hospital, Serbia. Report 21 July.

11 August update

194. Belma Soljanin contracted Covid-19 at 35 weeks (click here). She was delivered by Caesarean on 6 August at the Clinical Centre University Sarajevo Gynecology and Obstetrics Clinic. The baby tested negative and survived, but she died on August 9th in Podhrastovi ward in Sarajevo. Report 9 August.

193. Brittany Lance, from Rockford Illinois, contracted Covid-19 at 28 weeks. She required ventilation and spent 40 days in ICU (click here). Her baby was born prematurely by Caesarean. Report 5 August.

192. Sonam Sreekant contracted mild Covid-19 during her pregnancy (click here). She was nursed at home and recovered. The pregnancy is ongoing. Report 11 August.

191. Nadu Morgan contracted Covid-19 at between 12 and 16 weeks gestation (click here). She was initially treated at Nkhoma Hospital and later transferred to Kamuzu Central Hospital in Lilongwe, Malawi. She recovered. The pregnancy is ongoing.  Report 4 August.

190. Haley Peterson contracted Covid-19 at 19 weeks gestation (click here). Her symptoms were mild and the pregnancy is ongoing. Report 5 August.

189. Ebony Brown-Olaseinde contracted Covid-19 at 27 week gestation with twins. She required ventilation and delivery by Caesarean at 28 weeks at Saint Barnabas Medical Center in Livingston, New .Jersey (click here). Mother & babies survived. Report 6 August.

188. Brittany Hartwell, from Brevard county, Florida, contracted Covid-19 while pregnant. Her baby was born by Caesarean at AdventHealth at 27 weeks (click here). Both recovered, but the baby had a grade 4 intra-ventricular bleed. Report 7 August.

187. An unnamed woman died after childbirth at the Manati Hospital in Puerto Rico on 18 July (click here). Report 22 July.

186. A newborn baby in Basildon tested positive two days after birth on May 11 (click here). The mother, Presley Dowdall, had pre-eclampsia and obstetric cholestasis, but tested negative. Both recovered. Report 30 July.

185. An unnamed 24-year-old woman with COVID-19, gave birth to a healthy daughter at Regional Institute of Medical Sciences, Imphal, India, on August 10th (click here). Report August 10th.

184. Molly Grantham, from North Carolina, contracted Covid-19 postnatally. She developed pneumonia but recovered. Her baby remain uninfected (click here). Report 7 August.

31 July update

183. 19-year-old Janete Vasconcelos da Silva, contracted Covid-19 at 8 months gestation and was cared for at a hospital in Santarem, Para State, Brazil on July 17, 2020 (click here). Report 21 July.

182. There have been 2,842 infections among pregnant and post partum women in Mexico, and 83 deaths (click here). Report 13 July.

181. Three mothers tested positive at the Pumwani maternity hospital in Nairobi, Kenya (click here). No babies were affected. Report 14 July.

180. Amandine tested positive for SARS-CoV-2 and gave birth to Mahaut by Caesarean at CHIREC Delta Hospital in Brussels, Belgium April 25, 2020 (click here). Both mother and baby were doing well. Report 26 April.

30 July update

179. Essence Townsend from Scottsdale, Arizona contracted Covid-19 at about 32 weeks (click here). The pregnancy is ongoing. Report 27 July.

178. Three pregnant women with Covid-19 have been turned away by hospitals in Kolkota, West Bengal (click here). The outcomes appear to have been good. Report 28 July.

177. Kia Anderson, from Memphis, Tennessee, contracted Covid-19 at 23 weeks (click here). She self-isolated at home and recovered. The pregnancy is ongoing. Report 27 July

176. 54 pregnant women have been diagnosed with Covid-19 in El Paso, Texas (click here). No newborns have tested positive. Report 28 July.

175. An unnamed woman gave birth at term at the end of May in Sassoon hospital, Pune, India (click here). She had no symptoms but had SARS-CoV-2 antibodies. The baby had fever, lethargy and signs of severe Covid-19, tested positive and recovered. Report 28 July.

174. Accidental duplicate of Report 72. Veronica Markley contracted Covid 19 at 27 weeks gestation (click here). She was cared for at Presbyterian St. Lukes hospital in Denver, Colorado, and required ventilation for some days. She recovered and gave birth at term. She tested positive again on the day of the birth. The baby was fine. Report 29 July.

27 July update

173. An unnamed woman with Covid-19 gave birth on 22 July at Govind Ballabh Pant Hospital in Agartala, in Tripura, NE India (click here). Both “mother and child are safe”. Report 23 July.

172. An unnamed woman with Covid-19 gave birth at Diphu Medical College & Hospital (DMCH) in Karbi Anglong district in Assam, India (click here). Both mother & child are in a ‘stable’ condition. Earlier Runjun Mahanta and Kankana Barman, who both had Covid-19, gave birth to healthy babies in Kokrajhar, Assam. Report 27 July.

25 July update

171. Kaillee Dyke contracted Covid-19 at 27 weeks gestatiowith twins, and required ventilation in the intensive care unit at Royal Melbourne Hospital, Australia (click here). At the time of the report she remained on the ventilator, the pregnancy was ongoing and the babies were undelivered. Report 19 July.

170. Marzanne Lennox contracted Covid-19 at 30 weeks gestation and required 2 weeks ventilation at Life Wilgers Hospital in Pretoria, South Africa (click here). She survived. The baby was stillborn and delivered by Caesarean. Report 16 July.

20 July update

169. One hundred women with Covid-19 have given birth at Vani Vilas Hospital in Bengaluru, India (click here). The hospital has treated up to 350 pregnant women with Covid-19. Report 17 July.

168. A woman with Covid-19 gave birth by Caesarean at the All India Institute of Medical Sciences (AIIMS)-Patna on 19 July (click here). The baby has not yet been tested. Report 20 July.

167. Ten women with Covid-19 gave birth in Gauhati Medical College and Hospital in Assam, India (click here). Report 19 July.

18 July update

166. Sarah Green from San Antonio in Texas is pregnant and contracted COVID-19 (click here). She is self isolating at home and the pregnancy is ongoing. Report 18 July.

165. Rocio Casalduc from New Hampshire contracted Covid-19 during her pregnancy and was anaeshetised. presumably ventilated, and her baby delivered (click here). Both survived. Report 18 July

15 July update

164. Diana Angola, 36, contracted Covid-19 at 26 weeks. She required ventilation and Caesarean section, at the Versaille clinic in Cali, Colombia (click here). She recovered. Her son Jefferson tested negative and remains in hospital. Report 29 June.

163. Sarah Scully, age 35, from Birmingham UK contracted Covid-19 at a late stage of her prengancy (click here). She was delivered by Caesarean section at Birmingham Women’s Hospital on 12 April. After a month of intensive care she died on May 12. The baby survived. Report 20 June.

162. Aurora Chacon Esparza, age 35, from Minnesota, contracted Covid-19 at 30 weeks gestation. She required ventilation and was delivered by Caesarean at North Memorial Hospital in Brooklyn Minneapolis. The baby survived, but she remains critically ill on a ventilator (click here). Report 11 July. Update 11 August. She died on 18 July (click here).

161. Larissa Blanco was pregnant with twins. She had flu like symptoms and tested positive for SARS- CoV-2 on June 12. The Covid-19 was reported to have been mild. The twins were born at a private hospital in Botucatu, Sao Paulo on June 27, but she died soon after from bleeding (click here). The twins survived. Report 2 July.

160. Dora Nginza Hospital in port Elizbeth S Africa has treated 19 pregnant patients who have tested positive for Covid-19 (click here). The hospital treated its first case in pregnancy on 30 March (click here). Reports 9 April & 24 June.

14 July update

159. Esbeidy Reyes contracted Covid-19 at about 28 weeks, and was admitted to the ICU at Memorial Hermann Hospital in the Texas Medical Center. She was treated with immune plasma from someone who had recovered from the virus (click here). She recovered. The pregnancy is ongoing. Report 28 June.

158. The Institute of Obstetrics & Gynaecology (IOG) & Government Hospital for Women and Children, Egmore, in Chennai, has treated 294 women who tested positive for SARS-CoV-2. None have died.  Kasturba Gandhi Hospital (KGH) for Women and Children, Triplicane has cared for 229 positive women of whom 187 have been discharged, but no further details are available (click here). The Government Kilpauk Medical College Hospital has 30 COVID-19 positive pregnant women. At least 10% of babies are reported to have tested positive. No details were available for Chennai’s largest maternity hospital, Government RSRM Lying-in Hospital, Royapuram. Report 20 June.

157. Morgan Brink, from Johannesburg South Africa, tested positive for SARS-CoV-2 at 22 weeks gestation. She recovered and her son was born by Caesarean at 35 weeks on 11 July. He is recovering (click here). Report 14 July.

13 July update

156. Rocio Martinez contracted Covid-19 at 20 weeks (click here). She recovered, and the pregnancy is ongoing. Report July 8.

155. An unnamed woman from Hesperia, California died from Covid-19 on 26 June (click here). The baby survived and tested negative. According to the report she was the 2nd pregnant woman to die from the disease in California. At the time of the report 72 pregnant women in San Bernardino County had contracted COVID-19. Report 10 July.

154. Maggie Sillero was 28 weeks pregnant with triplets when she tested positive for SARS-CoV-2 (click here). She remained asymptomatic and was delivered by Caesarean at the Woman’s Hospital of Texas in Houston at 32 weeks. The babies all did well. Report 9 July.

153. The wife of professional tennis player Viktor Troicki is pregnant and has tested positive for SARS-CoV-2 (click here). Report 23 June.

26 June update

152. An unnamed 40-year-old woman, with SARS-CoV-2, gave birth to a baby girl at Lagos University Teaching Hospital, Nigeria (click here). Both mother and the baby “are doing fine.” Report 27 April.

24 June update

151. An unnamed 24-year-old woman with Covid-19 and an ectopic pregnancy died in the Gautam Budh Nagar district of Uttar Pradesh, India, on 19 June (click here). Report 20 June.

150. Five pregnant girls have contracted Covid-19 at a state-run children’s shelter in Uttar Pradesh’s Kanpur districy (click here). They are being treated at Kanpur Medical College. No further details. Report 22 June.

149. An unnamed woman with Covid-19 was delivered by Caesarean section at 31 weeks in the Semmelweis Hospital in Budapest (click here). The baby tested negative. Report 23 June.

23 June update

R 20 update. Karen Mannering (report 20 here) gave birth to a healthy baby on 16 June (click here). Report 22 June.

148. A unnamed asymptomatic woman with SARS-Cov2 gave birth to triplets in Mexico on May 8th. (click here). The babies tested positive on the day of birth but are reportedly “not in danger”.  Report 23 June.

147. An unnamed 20-year-old woman who tested positive for coronavirus on June 14 gave birth on June 15 in a COVID care centre in Amravati in Maharashtra. Both mother and baby recovered. Another unnamed woman with COVID-19, from Rohankheda village in Morshi tehsil, gave birth to a boy on June 19 (click here). Both also recovered. Report 22 June.

146. Kate Foxall, 36, from Charminster contracted Covid-19 at 38 weeks, and gave birth to Ostara at St Mary’s Maternity Unit in Poole on May 15 (click here). Ostara’s coronovirus status was not reported but she was fine. Report 22 June.

145. An unnamed  29-year-old woman from Sombrerete in Mexico gave birth to triplets prematurely by Caesarean section on May 6th at Zacatecas Women’s Hospital (click here). She tested positive postnatally. The babies all tested negative. Two died from prematurity. Report 14 May

18 June update

144. Monica V. Garcia from Elizabeth, New Jersey contracted Covid-19 during pregnancy (click here). She recovered without special treatment. The baby is due August 3. Report 22 May.

143. Three pregnant women with Covid-19 in the Cayman Islands recovered with no special treatment (click here). No further details. Report 15 June.

15 June update

142. The Nair hospital in Mumbai successfully completed 302 deliveries of Covid-19 positive women. Doctors said none of the babies born in last two months had tested positive at the time of birth (click here). Report 15 June.

141. An unnamed woman with Covid-19 from Old Dhaka gave birth to a baby boy at Dhaka Medical College Hospital in Bangladesh (click here). Both recovered. Report 17 May.

140. An unnamed woman in late pregnancy tested positive in Meghalaya, Bangladesh (click here). No further details given. Report 10 June.

14 June update

139. Liberian nurse Sedia Marwolo, aged 38, was 32 weeks gestation when she contracted Covid-19 (click here). She recovered and later had a healthy baby. Report 23 May.

Update (click here) of report 17 from Baton Rouge (click here). The mother, who had required ventilation but laboured spontanously at 21+6 days, and whose baby had died soon after birth, is named as Kenna Allen. She recovered. Report 10 June.

138. An unnamed women contracted Covid-19 at 28 weeks gestation, and required delivery at 29 weeks at Dubai’s King’s College Hospital London (click here). The baby was not infected and both recovered. Two other women with less severe disease in the same hospital also recovered and their babies were not infected. Report 11 June.

137. Danielle Wood, age 32, contracted Covid-19  at 32 weeks gestation (click here). She self-isolated at home. Her baby born at 38 weeks was not infected. Report 12 June.

8 June update

136. A woman, identified only as Ilse, developed Covid-19 at 31 weeks gestation (click here). She required ventilation at Rodolfo de Mucha Macías hospital in Mexico City. At 34 weeks she was delivered by Caesarean. The baby tested negative and both recovered. The hospital has cared for four other women with Covid-19. Three recovered and their pregnancies are ongoing. No details were given of the fourth. Report 3rd june.

135. Rusia Goes, aged 42, from Rio de Janeiro developed Covid-19 at 8 months gestion (click here). She required ventilation and delivery by caesarean. The baby tested negative and was isolated from her. She eventually recovered. Report 26 May.

7 June update

134. An unnamed 20 year old woman died after giving birth at 7 months gestation to a stillborn baby in Vellore Medical College and Hospital (click here). The birth was by Caesarean section and the cause of death was reported as complications of pregnancy-induced hypertension. She had tested positive for Sars-Cov2. Report 6 June.

133. 79 pregnant women have tested positive for COVID-19 in Kashmir (click here). Mainly from the Anantnag district. No further details. Report 6 June.

132. Neelam Kumari, age 30, from Ghaziabad in Uttar Pradesh, died in the eighth month of her pregnancy of Covid-19 (click here). Report 7 June.

131. Abi Atkin, aged 34, from Sheffield contracted mild Covid-19 at 34 weeks (click here). She recovered without treatment and gave birth normally at term. Report 6 June.

5 June update

130. An unnamed 22-year-old woman from Padarayanapura, Bengaluru, India, contracted Covid-19 at 8 months gestation (click here). No further details. Report 5th June.

2 June update

129. Michelle Hunter contracted Covid-19 at term (click here). Her son, Hank, was delivered by Caesarean section at an unnamed Vernon, British Columbia hospital. He tested negative. Report 30 May.

1 June update

128. Wafa Boudissa, age 28, died of the coronavirus at 8 months gestation (click here). She was a doctor working in the Intensive Care unit of Ras El Oued hospital in eastern Algeria. Report May 18.

127. A unnamed 28-year-old woman, who was six months pregnant, died in Kalsekar hospital, Mumbra, India after three private hospitals refused to admit her because of suspected Covid-19 (click here). Her death certificate says she died of Acute Respiratory Distress Syndrome (ARDS) with suspected Covid. HT @DeepakNModi. Report 29 May.

31 May update 

126. Vegan lifestyle vlogger Rachel Ama contracted Covid-19 at 11 weeks gestation (click here). She recovered and the pregnancy is continuing. Report 30 May.

30 May update

125. Hilda Garson, age 28, from Manitoba, tested positive for SARS-Cov2 in March (click here). She self isolated, is now 21 weeks, and the pregnancy is ongoing. Three other pregnant women in Manitoba are reported to have tested positive. Report 28 May.

124. Rashmi Kapoor tested positive at term and delivered in Lok Nayak Jai Prakash Narayan Hospital in New Delhi (click here). Report 27 May.

123. Amanda Joyce, from Boston, Massachusetts, contracted Covid-19 on March 19th at about 21 weeks gestation (click here). She self-isolated at home and the pregnancy is ongoing. Report May 29.

28 May update Reports 121 and 122 added.

122. A belated addition. An anonymous woman with Covid-19 in Wuhan (click here) gives birth to an infected baby. Report 5 Feb.

121. Candice Bowie contracted Covid-19 in April in prison in Louisiana at 8 months gestation. On May 4th she was released and went to an unnamed hospital where she was scheduled to deliver by Caesarean (click here). Report 18 May.

26 May update Reports 115-120 added.

120. Diamond, a pseudonym, developed mild Covid 19 at term and delivered at Toronto’s Michael Garron Hospital (click here). Mother and baby survived. Report 21 May.

119. Tasnim Shaheen developed severe Covid-19 at about 28 weeks gestation. She required ventilation and Caesarean at Jamaica Hospital in Queens, New York (click here). Mother and baby are still in hospital but recovering. Report 11 May.

118. An unnamed 20-year-old coronavirus positive woman from Medchal has given birth to twins by Caesarean section at Gandhi Hospital in Hyderabad (click here). The mother was asymptomatic. The twins are awaiting testing. Report 26 May.

117. Lisseth Hernandez developed Covid-19 at 29 weeks gestation with twins. She required ventilation and was delivered at 30 weeks by Caesarean (click here). She recovered. The babies were isolated and did well. Report 19 May.

116. There are 2,561 pregnant women in Russia with coronavirus infection. 2,035 tested positive for SARS-Cov2. Presumably the rest are clinical diagnoses (click here).  There are 816 pregnant women with the coronavirus infection in Moscow alone. Report 25 May.

115. Katie Miller, the spokeswoman for US Vice President Mike Pence, is pregnant and has tested positive for SARS.Cov2 (click here). She has recovered and is back at work. The pregnancy is continuing. Report 26 May.

21 May update Reports 111-114 added.

114. Claire Trusson, age 37, developed Covid-19 at 34 weeks (click here). It was an IVF pregnancy. She gave birth at St Helier Hospital in Carshalton. Both recovered. Report 29 April.

113. Shaquilla James, of Summerton, South Carolina developed Covid-19 at 38 weeks gestation (click here). She gave birth the same day at McLeod Regional Medical Center in Florence, SC, but later was put on a ventilator. Mother & baby both recovered. Report 20 May.

112. Alicia Kappers, age 40, was 31 weeks when she developed Covid-19 on March 24 (click here). She was cared for at the TriHealth Good Samaritan Hospital in Cincinnati, Ohio, where she required prolonged ventilation and a tracheostomy. She went into pre-term labour at 32 weeks and was delivered by Caesarean. The baby tested negative. Both are recovering at home. Report 17 May

111. There have been 115 babies born to Covid-19 infected mothers at the Lokmanya Tilak Municipal General Hospital – also called Sion Hospital – in Mumbai (click here). Three babies were infected, but recovered. Two mothers died, one of whom was aged 28 and died after giving birth.  Report 21 May. (HT Francis Githae Murithi)

18 May update – report 109 added.

110. An unnamed woman with Covid-10 gave birth in the North Ossetia city of Beslan (click here). Both mother and baby are now home. The head of the unnamed hospital’s maternity unit, Hassan Tagaiev, said that 17 of 35 women who were about to give birth there had tested positive for Covid-19.  Report 18 May.

109. Kimberly Phillips, age 44, who had Covid 19, gave birth on May 2nd, at 40 weeks gestation, at the Princess of Wales hospital in Bridgend (click here & here). Her baby, Coolio Carl Justin Morgan, died age 3 days. The primary cause of death was hypoxic ischemic encephalopathy, secondary cause maternal Covid-19. Kimberley is reported to have needed intensive care but has now been discharged. Reports 13, 14 May

17 May update reports 107 & 108 added

108. An unnamed 29-year-old from Sindhupalchowk district in Nepal gave birth on May 6, and died of COVID-19 on May 16, in Kathmandu (click here). Report 17 May

107. An unnamed 27-year-old, from Dharavi slum in Maharashtra, tested positive for coronavirus in Belagavi city on 14 May (click here). She was 7 months gestation. Dharavi is in Mumbai . Belagavi is 500 km to the south. Report 15 May

16 May update – reports 105 & 106 added

106. Ten pregnant women with Covid-19 have been were treated at Sheba Medical Center at Tel Hashomer Hospital in Tel Aviv (click here). Four have given birth, one of whom was in critical condition and was transferred to ICU. Report 15 May.

105. An unnamed woman with SARS-COV-2 gave birth at 39 weeks gestation in Indraprastha Apollo Hospital, New Delhi  (click here). The baby was not infected. Report 15 May.

13 May update – reports 103 and 104 added.

104. Mili América Antelo, age 40, was pregnant with twins at when she developed severe Covid-19 at 28 weeks gestation (click here). She required Caesarean section and spent 11 days in intensive care (7 on a ventilator) at Vall d’Hebron hospital in Barcelona. The twins both tested negative. Mili has now been discharged. Report 11 May.

103. The Los Angles Times reports that roughly 134 pregnant women have tested positive, in LA county (click here). Over 82% of them were symptomatic. There have been 29 live births, and one stillbirth. Twenty-four infants were tested at birth, including one set of twins, and none tested positive. The virus has not been detected in amniotic fluid, breast milk or other “maternal samples”. Report 11 May.

10 May update – cases 97-102 added

102. Six women with COVID-19 have given birth in a government hospital in Peru. Five babies were healthy and have been discharged. The sixth woman remains in a serious condition in the intensive care unit. Her baby was born prematurely and remains hospitalized. None of the babies tested positive for COVID-19 (click here). Report 9 May.

101. Jessa Yager, from Grand island, Nebraska, developed Covid-19 while pregnant  (click here). She is recovering and the pregnancy is ongoing at 36 weeks. Report 7 May.

100. Rachel Bailey from Shelby County, Alabama, was 5-months pregnant when she developed Covid-19 (click here). She is now 30 weeks and recovering. The pregnancy is ongoing. Report 6 May

99. Patient 765, a 20-year-old woman from Padrayanpura, in the late stage of pregnancy, tested positive on 8 May at Vani Villas Women and Children Hospital in Bangalore, Karnataka, India (click here). No further details. Report 9 May.

98. Florette Johnson from Florida, had Covid-19 around term. She had a vaginal birth but later required ventilation (click here). The baby was isolated. Both mother and baby are recovering. Report 9 May.

97. Monique Cook from Atlanta, Georgia, developed Covid-19 at 8 months gestation with twins. She was delivered by Caesarean section at Piedmont Henry hospital on 22 March, and transferred to Piedmont Atlanta hospital for ECMO treatment (click here). She was extubated after 5 days and is now recovering at home.  The twins have also been discharged. Report 8 May

9 May update

96. Gabriela Maia, the wife of Max Johnson, the half brother of British prime minister Boris Johnson, is pregnant, and has Covid-19 (click here). She is recovering. Report 28 March.

95. A baby born at 30 weeks gestation on April 3, in Natal, Brazil, tested positive for SARS- Cov2, and died age 4 days. The mother had respiratory symptoms but her test result was not yet available (click here). The authorities cannot confirm if the infection caused the death. Report 10 April.

8 May update – Cases 86-94 added.

94. Terra Eubanks, a pregnant nurse at Baton Rouge General Hospital in Louisiana, got Covid-19. She recovered (click here). The pregnancy is ongoing. Report 7 May.

93. Johana Rocio Mendoza Chancay, age 40, from Union City, New Jersey, was 26 weeks gestation when she developed Covid-19. She was transferred from Hoboken University Medical Center to Robert Wood Johnson University Hospital in New Brunswick where she gave birth by Caesarean section on March 30th (click here). Her daughter Zion weighed 1lb 13oz. The mother was ventilated and in a coma until April 13. Both recovered. Report 22 April.

92. An unnamed pregnant woman (referred to as P652) had an inconclusive Covid-19 test result at Dr Lal Path Labs in Delhi on 2nd May. The result was interpreted at positive and the woman was nursed on a Covid-19 ward. On May 6, a test at Bangalore Medical College and Research Institute’s Virus Research and Diagnostic Laboratory was declared negative. A third test at the National Institute of Virology’s Bengaluru Field Unit was also negative (click here). Report 8 May.

91. An unnamed pregnant woman is among five Lincolnshire police staff who have tested positive for coronavirus (click here). Report 5 May.

90. Katherine Dawson, aged 36, developed Covid-19 at 32 weeks gestation. She was delivered by Caesarean section at Blackpool Victoria Hospital on 1 April. Her condition deteriorated and she required artificial ventilation (click here). The baby, Ruby, was reported to be infected at birth. Mother and baby recovered, and were discharged on 6 May. Report 6 May.

89. An unnamed  28-year-old women, recovered from Covid-19 and was discharged from Symbiosis Hospital in her 37th week of pregnancy (click here). Report 24 April.

88. An unnamed five-month pregnant woman tested positive for coronavirus at the Pune Municipal Corporation’s Sonawane hospital (click here). She was transferred to Bharati Hospital. Report 14 April.

86. & 87. An unnamed 25-year-old pregnant woman with Covid-19 gave birth by Caesarean section on April 20 at the Sassoon General Hospital in Pune, India, to a healthy boy. Another unnamed woman with Covid-19 delivered by Caesarean section the same day in Aurangabad district civil hospital (click here). Neither baby was infected. Report April 20.

7 May update – cases 80 to 85 added.

85. An unnamed woman with Covid-19 gave birth in Nagaur in Rajustan, India, on April 23 to a baby who also tested positive (click here). Eight other pregnant women from the Ramganj area also tested positive. Report 24 April.

84. An unnamed pregnant woman who had recovered from Covid19 gave birth at her home in Kalnad, Kerala, India after being refused hospital admission (click here). She was later treated at Kannur Medical College Hospital in Pariyaram, before transfer to the General Hospital in Kasaragod for observation. The outcome was not reported. Report 4 May

82 & 83. An unnamed 35-year-old woman from Shangus in south Kashmir’s Anantnag district had Covid-19 at the time of her birth at the SKIMS Medical College Hospital Bemina, Jammu & Kashmir, India (click here). No further details are given. The same report notes that two other pregnant women “have died and nearly 10 have got infected with coronavirus in past two weeks” at the same hospital. It is not clear whether the two women who died had Covid 19. Elsewhere in the same report another woman, Firdousa Javaid is reported to have tested positive in a different maternity hospital, Lalla Ded. Report 6 May.

81. Melissa Brewer from Mountain Green, Utah, whose baby is due in May 2020, had minimal symptoms but tested positive for SARS-CoV2 (click here). The pregnancy is ongoing. Report 5 May.

80. Molly Baldwin, age 28, from Fitchburg, Massachusetts, developed Covid-19 at 33 weeks gestation (click here). She is self-quarantining at home. The pregnancy is ongoing. Report 5 May

5 May update – cases 78 & 79 added

79. An unnamed baby developed Covid-19 at age three months and was treated at Baba Raghav Das Medical College, Gorakhpur, Uttar Pradesh between April 12 and 26th (click here). His mother was SARS-COV-2 negative and continued to breast feed him. The baby recovered and the mother remained negative. Report 5 May.

78. An unnamed woman with Covid-19 gave birth at Aurangabad Civil Hospital in Maharashtra, India (click here). The baby was not infected. Report 5 May.

4 May update – cases 74 to 77 added.

77. Sarita [a pseudonym] from Los Angeles was asymptomatic, but tested positive for SARS-COV-2 during her pregnancy (click here). Her baby, born mid April, was isolated from her and tested negative. At four days of age the baby suffered some sort of respiratory arrest, but recovered. Report 1st May

76. Silvia Leroy, age 35, developed Covid-19 and was transferred from Brookdale, her local hospital, to Mount Sinai hospital in Manhattan (click here). She was on a ventilator for a week, but appeared to be recovering, when she had a cardiac arrest. Her baby, Esther, was delivered by Caesarean section. Sylvia is alive but reported to have brain damage. Report 29 April.

75. Kim Stidworthy, age 25, from New Mexico was 20 weeks gestation when she developed Covid-19 (click here). She spent four days in hospital. The pregnancy is ongoing. Report 1st May.

74. Tamekia Melong, age 37, from Baldwin, Long Island, New York is pregnant and developed Covid-19 in March (click here). The pregnancy is ongoing. Report 3rd May

30 April update – Cases 71 to 73 added. Also up to 10 pregnant women had tested positive for corona virus in the Rotunda Hospital in Dublin (click here) by 1 April. Report 1 April.

73. Alysha Ramos, age 29, pregnant with Covid-19, is in prison in Valparaiso, Indiana (click here & here). Reports 5 & 23 April.

72. Veronica Markley, age 37, from Colorado had Covid-19 at 30 weeks gestation (click here). She was intubated and put on a ventilator at Presbyterian/St. Luke’s Medical Center in Denver, but is recovering. The pregnancy is ongoing. Report 27 April. See report 174. Update 4 March 2021. Both her and the baby recovered (click here).

71. Ashley Duque, age 33, from San Diego developed Covid-19 at 17 weeks gestation (click here). She required 4 days ventilation but is recovering. The pregnancy is ongoing. Report 10 April.

29 April update – Cases 63 to 70 added.  Case 9 – Carrie Symonds, the partner of British Prime Minister Boris Johnson, who gave birth to a healthy baby boy on April 29th, updated. Case 61, an accidental duplicate, deleted. Maternal and baby deaths highlighted in bold.

70. Jennifer Laubach from Clarkston, Michigan, gave birth to twins at 32 weeks at Troy Beaumont Hospital. The babies were isolated because she had symptoms and her partner had Covid-19. She later tested positive (click here). She and the twins recovered. Report 29 April.

69. Abigail Jacobs, age 29, from Kahnawake near Montreal, Canada, developed Covid-19 symptoms in mid March at 24 weeks gestation (click here). Her first test was negative, but a repeat on March 29 was positive. She self-isolated and has recovered. The pregnancy is ongoing. Report 18 April.

68. An unnamed woman from Charlotte, North Carolina, who is three and a half months pregnant tested positive for COVID-19 (click here). Report 14 April.

67. Kim Anderson, age 36 from Idaho Falls developed Covid-19 on March 22nd at about 8 months gestation (click here). She required oxygen therapy in hospital but not ventilation. The pregnancy is ongoing. Report 15 April.

66. A unnamed woman who is four months pregnant is the first pregnant COVID-19 patient admitted to Victoria Hospital in Karnataka, India (click here). Report 31 March.

65. An unnamed pregnant woman age 35 from the Kharpora Kokernag area of Anantnag in Indian administered South Kashmir was admitted to the Maternity and Child Care Hospital in Anantnag (click here). She gave birth to stillborn twins and died soon after. Her test results later confirmed that she was Covid-19 positive. It is reported that Syed Yasir, the commissioner of the region, believes the cause of death was negligence rather than Covid-129. An enquiry is ongoing. Report 27 April.

64. Amanda Joyce, age 33, who works at Newton Wellesley Hospital on the outskirts of Boston, Massachusetts, developed Covid-19 while pregnant (click here). She self-isolated at home, and the pregnancy is ongoing. Report  17 April.

63. Andrea Circle Bear, age 30, from Eagle Butte, South Dakota was pregnant and an inmate in a US Federal prison when she developed Covid-19 (click here). She was transferred to Carswell, a federal prison medical facility in Fort Worth, Texas, and thence to a local hospital where she was delivered by Caesarean section on 2 April. She died on 28 April. The baby’s status was not reported. Report 29 April.

28 April update – cases 58 to 62 added

62. Morgan Brink, age 30, from Roodeport in South Africa, tested positive for coronavirus on 25 March (click here). She had a cough and is self-isolating at home. Report 9 April.

61. Marie Youri, age 19, who had Covid-19, gave birth on 11 April in Yaoundé, the capital of Cameroon (click here). She is on oxygen therapy, & baby Foraya, birth weight 2.1kg, is in isolation. Report 12 April. Accidental duplicate

59 & 60. The deaths of two unidentified women in Mexico (click here). (Report cited in Study 66 here). Report 9th April.

58. Viviane Albuquerque, age 33 from Pernambuco, Brazil, died from Covid-19 at 32 weeks gestation (click here). The baby, delivered by Caesarean, survived. (Report cited in Study 66 (here) which also cites two other newspaper reports of maternal deaths in Brazil, but the links provided miss the reports.) Report 6th April.

26 April update – cases 55 to 57 added

57. Danielle Martin, age 32, from Belfast, Northern Ireland, developed Covid-19 while pregnant with twins at nine weeks (click here). She required artificial ventilation but recovered, and the pregnancy is ongoing. Report 23 April. Update 9 October (click here), she gave birth to healthy twins early in October.

56. Molly Burdick, from Portland in Oregon had Covid-19. 18 days later she was treated for a ruptured (tubal) ectopic pregnancy (click here). She recovered. Report 21 April

55. Sally Nuza, from Ascot, Berkshire developed Covid-19 at 8 months gestation (click here). She recovered, the pregnancy is ongoing, and her unborn baby son is ‘perfectly healthy’. Report 24 April.

24 April update – Cases 53 & 54 added.

54. Wogene Debele from Maryland died of Covid-19 three weeks after giving birth (click here).  Report 23 April

53. Fozia Hanif age 29 developed Covid-19 and gave birth by Caesarean section on 2nd April. She died in Birmingham Heartlands Hospital on April 8th (click here). Report 23rd April

21 April update – Cases 50 to 52 added.

52. Jasmine Jones age 26 from Indianapolis, Indiana, and pregnant with twins, tested positive on March 22nd, at 33 weeks (click here). She was symptomatic, self-isolated at home and the pregnancy is ongoing. Report 20 April.

51.  Silvana Vergara from New York caught the virus at 22 weeks gestation (click here). She was “reassured”, so presumably has recovered and the pregnancy is ongoing, although this is not specifically stated. Report 18 April.

50. Sarah Manning tested positive for SARS-COV-2 a few days before giving birth in Jersey’s midwifery unit (click here). Presumably a normal vaginal birth. Mother and baby are pictured, unmasked, bottle feeding and not separated. Report 20 April.

19 April update Cases 47 to 49 added.

49. An unnamed woman developed symptoms of Covid-19 soon after giving birth in Strong Memorial Hospital, Rochester, New York (click here). Whether she, her partner, or the baby, tested positive has not been disclosed. Report 31 March.

48. Jennifer Kruman, age 33, of Crown Heights, Brooklyn, tested positive 12 hours after giving birth to baby Isaac Hai Kruman, on March 31, at Mount Sinai West Hospital, Manhattan (click here). Isaac tested negative and both went home after 24 hours. Report 17 April.

47. Octobeya Scott, age 30, developed COVID-19 pneumonia at 33 weeks gestation (click here). She was delivered by Caesarean section under general anaesthesia, on March 22 at Jack D. Weiler Hospital of the Albert Einstein College of Medicine, The Bronx, and ventilated for a further five hours. The baby, Alicia Anderson, was separated for five days. Both have now returned home. Report 18 April.

18 April update Cases 42 to 46 added.

46. Salina Shaw, age 37, from Southend in Essex, who had tested positive for Covid-19, gave birth on 4 April and died on 12 April (click here). Report 17 April.

45. Kilee Coye, age 25, from Canastota, New York State, has tested positive for the virus, and has some symptoms. She is 35 weeks pregnant (click here). Her partner also has Covid-19 and is on a ventilator. Report 15 April.

44. Lidia Puerta, age 26, from Spain tested positive at eight months gestation (click here, para 10). She was in quarantine in a hospital in Singapore, and the pregnancy ongoing at the time of the report. Report 22 March.

43. Yanira Soriano, age 36, developed Covid-19 at 34 weeks gestation (click here). She required ventilation and the baby was delivered by caesarean at Southside Hospital in Bay Shore, New York. The baby tested negative. Mother and baby have been discharged. Report 16 April.

42. Megan Sites age 27 from Celina, Ohio, contracted Covid-19 at 29 weeks gestation (click here). She required ventilation, and later ECMO, and the baby was delivered by Caesarean section at 29 weeks. The baby, tested negative twice, is currently on NICU. The mother has improved slightly. Now off ECMO, but still ventilated.  Report 16 April.

16 April update Case 40 & 41 added.

41. Actress Patti Murin, age 39, probably has Covid-19, but has not been tested, and is self-isolating at home in California (click here). She is pregnant and due in July, so about 27 weeks gestation. Report 9 April.

40. Mary Agyeiwaa Boateng, née Agyapong, age 28, died on 12 April, in Luton & Dunstable Hospital UK from Covid-19 (click here). Her baby was reported to be “doing very well”. Report 15 April.

14 April update Cases 35-39 added

39. An unnamed woman with Covid-19 is delivered by Caesarean section at 32 weeks gestation at a public hospital in Nairobi (click here). The obstetrician used a pseudonym because she was not authorised to speak to the media.  No further details were given. Report 13 April.

38. Angela Primachenko age 27 from Vancouver was diagnosed with Covid-19 at 33 weeks and became seriously ill. She gave birth at 34 weeks after induced labour, while being ventilated at Legacy Salmon Creek Medical Center (click here). Her daughter was isolated in intensive care and has tested negative. Mrs. Primachneko has been discharged home. Report 13 April.

35-37. This report in The New York Times (click here) describes Precious Anderson, pregnant & critically ill with Covid-19, and two other unnamed women. The piece also mentions 29 pregnant or delivering women with suspected or confirmed Covid-19 in the Brooklyn Hospital Center. No mother or baby had died, and there had been no confirmed cases among newborns. The Brooklyn Hospital Centre is separate from the Presbyterian Allen Hospital & Columbia Irving Medical Center, so presumably these cases have not been reported in an academic paper yet. Report 12 April.

13 April update Cases 32-34 added. HT @danieladrandic.

34. An unnamed woman, delivered by Caesarean section at the MedLife Grivita private maternity hospital in Bucharest on March 13th, developed pneumonia after birth (click here). A test taken on March 20th was positive and she was transferred to Matei Bals Hospital, the Covid-19 treatment center in Bucharest. At the time of transfer mother and baby were reported to be in good condition (click here). Report 24 March.

33. These ten asymptomatic babies, in a maternity unit in the Romanian city of Timisoara, were apparently not infected in pregnancy or by their mothers (click here). “The mothers tested negative, but the babies tested positive so we have to consider their contacts with medical staff.” Report 7 April.

32. An unnamed mother died in the University Clinic of Gynaecology & Obstetrics in Skopje, North Macedonia. Her baby had died before birth. Neither death was directly due to Covid-19, but according to the report the mother, who had been transferred from Ohrid General Hospital, had her treatment delayed while Covid-19 test results (eventually negative) were awaited. This delay may have contributed to her death (click here). An investigation is ongoing. Report 6 April.

12 April update

31. An unnamed woman with Covid-19 was delivered by Caesarean section in the King Abdullah University Hospital in Irbid, northern Jordan (click here). The baby was isolated from the mother and has reportedly tested negative. Mother and baby doing well. Report 29 March.

30. Sophie Biddle, age 37, was diagnosed with Covid-19 on March 7th, but has recovered (click here). Her 20 week scan on March 23 was reportedly normal and the pregnancy is ongoing. Report 30 March.

10 April update cases 26 – 29 added.

29. An unnamed woman in Ritsona refugee camp 40 miles north of Athens tested positive for Covid-19 a day or two after giving birth (click here). Reort 2 April.

28. 19-year old Marie Youri with Covid-19 gave birth prematurely in Yaounde, Cameroon (click here and here). She is said to be doing well with oxygen treatment. The baby Foraya weighed 2,100 grams and has not displayed any coronavirus symptoms. Report 8 April.

27. An unnamed 22-year-old woman with Covid-19 from Kyengera, Wakiso District, Uganda gave birth by Caesarean Section at Entebbe Grade B Hospital on April 5th (click here). Mother and baby were said to be in good health. Report 6 April.

26. An unnamed pregnant woman from Nallasopara died at Nair Hospital in Mumbai on April 4 (click here). Her baby was reported to have died in-utero before admission. She had been referred from a local hospital in Nallasopara after her condition deteriorated. It is reported that doctors suspect she died of Covid-19. A committee is investigating. Report 7 April.

A separate report (click here) of a 30 year old, nine month pregnant woman dying of Covid-19 in Mumbai may refer to the same woman. Report 6 April.

9 April update case 25 added.

25. Mallory Pease gave birth at Oaklawn Hospital in Marshall, Michigan to daughter Alivia on March 23 at term (click here). She was symptomatic and tested positive for Covid-19. Alivia was not infected. Route of delivery not reported. Mother and baby both now discharged. Report 8 April.

8 April update cases 19 – 24 added.

24. Raquel Iacurto, age 32, a teacher from New York, was admitted to Long Island Jewish Medical Center with respiratory symptoms at 25 weeks gestation on March 11 and tested positive (click here).  She was discharged after three days. The pregnancy is ongoing. Report 28 March.

23. Simone Shoffman, a beauty blogger from Bothwell, near Glasgow in Scotland is pregnant and has tested positive. She is undelivered at home (click here). Report 6 April.

21. & 22. Two unnamed pregnant women with COVID-19 gave birth in Rebagliati Hospital in Lima, Peru, the first on March 22, the second on March 31st, both by Caesarean (click here). Both mothers were reported to be in good health, and neither baby was infected. Report April 8th.

20. Karen Mannering, from Herne Bay, UK, was admitted to the Queen Elizabeth the Queen Mother Hospital in Margate on 21 March with respiratory infection. She tested positive on 25th March, when she was seven months gestation. She has since been discharged home and the pregnancy is ongoing (click here). Report 31 March, updated 1 April.

19. Michelle Wright, aged 37, who is 29-weeks pregnant, has tested positive for coronavirus. The pregnancy is ongoing. She is an inpatient at Russells Hall Hospital in Dudley, UK (click here). Report 7 April.

7 April update cases 16 – 18 added.

18. A newborn baby has reportedly tested positive for coronavirus at James Paget Hospital in Norfolk (click here). No details of the mother have been given. Report 18 March.

17. An unnamed woman with Covid-19 from Baton Rouge, Louisiana, is reported to have gone into preterm labour at 21 weeks (click here). The baby did not survive. The death was reported to the coroner so presumably the baby was born alive. The mother is reported to be on a ventilator. Report 6th April.  The coroner has reportedly decided that the death was due to coronavirus. The mother remains on a ventilator, update 7 April (click here).

16. An unnamed woman with Covid-19 has died during labour at The Whittingdon Hospital, London (click here). The baby survived. Covid-19 has not been ruled out as the cause, and the death has been referred to the Coroner. Report 6 April.

6 April update. Case 10, the first report, scientific or otherwise, of a COVID-19 birth from France, case 11 from Detroit, case 12, the first report from Greece, and two cases 13 & 14 from Egypt added. I’ve also belatedly added a case from Portugal from 17 March.

15. An unnamed woman with Covid-19 (click here) gave birth in Porto’s São João hospital on 17th March. She was described as “doing well”. No further details were given. Report 17 March.

14. An unnamed woman who had recently recovered from COVID-19 gave birth on 4 April by Caesarean section in Hurghada Hospital, (click here). Report 5th April.

13. A 30-year-old eight months pregnant woman infected with COVID-19, treated at Esna Specialized Hospital in Egypt is recovering (click here). The pregnancy is ongoing. Report 3rd April.

12. An unnamed 24 year old woman infected with Covid-19 has given birth at 40 weeks (term) at Attikon General Hospital in Athens, as reported by the state-run news agency ANA-MPA on 27th March (click here). She had tested positive on March 15 and was kept in the hospital for 2 weeks. The baby boy tested negative. No further details are given but both mother and baby are healthy and ready to go home.

11. First reported in the Detroit Free Press, (link broken). For “Click on Detroit” (click here). Jennifer Thompson from Warren, a Detroit suburb, developed symptoms on March 7th at 8 months. She tested positive on March 13th, and her son, Hollis, was born in Beaumont Hospital in Royal Oak, on March 28th. Birth details not reported, but mother and baby back home and doing well. Report 4 April.

10. The artist Ariane Chang @Arianechang describes her baby’s birth by elective Caesarean section under regional block at term on March 19th in “a private birthing clinic in the 15th arrondissement” in Paris, [Presumably Maternité Catholique Sainte Félicité] in the New York Review of Books (click here). She had had symptoms of COVID-19 for two days, and tested positive prior to a second operation under general anaesthesia to control intra-abdominal bleeding, the following day. Baby Clare, reportedly the first baby born to a COVID-19 mother in that clinic, was breast fed but not tested. Mother and baby recovering at home. Ariane Chang illustrates the article with her own paintings and drawings. Report 2nd April.

9. Carrie Symonds, the partner of British Prime Minister Boris Johnson is reported to have had symptoms of Covid-19 for a week (click here and many other sources). According to reports she has not been tested. Since the PM with whom she is living has had confimed COVID-19, it seems likely that she does too. Her due date has been reported as early July. Working back from a hypothetical EDD of 4th July would make her 27 weeks today.  Report 4 April. Update 29 April. She gave birth to a healthy baby boy.

8. Vanesa Muro “a carrier of Covid-19” gave birth to Oscar, birth weight 3.6 kg, by Caesarean on March 13 at the “Madrid hospital in La Paz” [more likely either La Paz university hospital or La Paz maternity hospital in Madrid] (click here).  (El Mundo report click here.) The date of her scheduled Caesarean had been brought forward by three days. Mother and baby were separated for 10 days. Oscar tested negative. Both well. Report 3rd April.

7. Urszula Osborne, age 41, a nurse in Boston Mass, contracted Covid-19 while eight months pregnant (click here). She is recovering and the pregnancy is ongoing. But her husband had severe disease requiring ventilation.  Report 3rd April

6. A 37 year old pregnant woman reportedly infected with Covid-19 died on 29 March after a Caesarean section at the Teresa Herrera Hospital in Coruña. The fetus had reportedly already died (click here). Details conflict, and the family are reported as disputing whether the death was due to Covid-19. An investigation is ongoing (click here). Report 30 March.

5. An unnamed woman age 27 is reported to have died from Covid-19 after giving birth in Łańcut in the south of Poland (click here and here). Report 20th March

4. Allegedly the first birth in Galicia to a mother with Covid-19 (click here). Baby Fabio, born at Álvaro Cunqueiro Hospital in Vigo by Caesarean section at 35 weeks. Birth weight 2.6 kg. Not infected. Mother and baby both doing well. Report 19 March.

3. Model, Michela Persico, partner of Juventus footballer, Daniele Rugani, (click here) is reported to be infected with SARS-COV-2 and is pregnant. The pregnancy is ongoing.  Report 19 March.

2. North Middlesex Hospital UK. Mother with Covid-19 pneumonia gives birth to an infected baby (click here). No further details. Report 14 March.

1 Valentina, is the partner of Matteo, who has been claimed to be Italy’s “patient one”. Matteo was seriously ill with Covid-19, but is reported to be recovering. Valentina is also reported to have developed less severe Covid-19, and is recovering at home. She is reported by La Republica (click here) to be eight months pregnant. At the time of the report, Valentina was undelivered. Report 9 March.

Jim Thornton

Covid-19 in Pregnancy; scientific studies

May 15, 2020

Primary clinical sources

In roughly reverse order. Updated regularly. Click here for ripe-tomato.org’s Covid-19 in pregnancy navigation page.  Curated by Jim Thornton, Keelin O’Donoghue & Kate Walker.

Ongoing update rules. Studies added in the order in which we find them. Study numbers never change (but see below). Inadvertent duplicates deleted. Each study report contains a link to original report, pdf, and full citation. Country, state and city recorded only once for ease of counting.  From February 1st 2021 we will selectively report laboratory studies of stored specimens such as sera and placentae. Such studies are important, but unless they also purport to report original clinical data, there is less need to note duplicate reporting.

Occasional [important] studies include early series, reliable registries, high-quality therapeutic trials in pregnancy (none yet), or basic science.

2 August 2021 – studies 765 to 771 added

Study 771 – 97 cases from US

Cared for at Weill Cornell Medicine, New York (click here or study). Likely overlap with studies 99, 118, 216, 230, 234, 276, 578, 669, and 758. Citation: Glynn SM, Yang YJ, Thomas C, Friedlander RL, Cagino KA, Matthews KC, Riley LE, Baergen RN, Prabhu M. SARS-CoV-2 and Placental Pathology: Malperfusion Patterns Are Dependent on Timing of Infection During Pregnancy. Am J Surg Pathol. 2021 Jul 26. doi: 10.1097/PAS.0000000000001772. Epub ahead of print. PMID: 34310367.

Study 770 – 40 cases from Turkey

Cared from Basaksehir Cam and Sakura City Hospital, Istanbul, which has not previously reported cases (click here or study). Citation: Yasa B, Memur S, Ozturk DY, Bagci O, Uslu SI, Polat I, Cetinkaya M. Severity of Maternal SARS-CoV-2 Infection in Pregnancy Predicts Neonatal Outcomes. Am J Perinatol. 2021 Jul 28. doi: 10.1055/s-0041-1733783. Epub ahead of print. PMID: 34320680.

Study 769 – 85 cases from US

Cared for at any of fourteen Advocate Aurora Health medical centers in Wisconsin and Illinois between March 23 and October 3, 2020 (click here or study). Three women required ventilation, but no mothers or babies died. This hospital network has not previously reported cases. Citation: Zlochiver V, Tilkens B, Perez Moreno AC, Aziz F, Jan MF. COVID-19 Deliveries: Maternal Features and Neonatal Outcomes. J Patient Cent Res Rev. 2021 Jul 19;8(3):286-289. doi: 10.17294/2330-0698.1848. PMID: 34322584; PMCID: PMC8297489.

Study 768 – 53 cases from Mexico

Cared for at the UMAE Hospital de Gineco Obstetricia “Luis Castelazo Ayala” Instituto Mexicano del Seguro Social, Mexico City from January to April 2021 (click here or study). This hospital has not previously reported cases, although they are likely included in the various national Mexico series. Citation: Carranza Lira S, Espinosa MG. Differences in the neutrophil/lymphocyte ratio and the platelet/lymphocyte ratio in pregnant women with and without COVID-19. Int J Gynaecol Obstet. 2021 Jul 29. doi: 10.1002/ijgo.13840. Epub ahead of print. PMID: 34322880.

Study 767 – 20 cases from China

From Tongji Hospital, Wuhan, between March 18 and May 9 2020 (click here or study). Likely reported many times before. Citation: Chen G, Zhang Y, Zhang Y, Ai J, Yang B, Cui M, Liao Q, Chen H, Bai H, Shang D, Chen J, Sun C, Liu H, Liu F, Mao B, Sun G, Chen L, Lin JW, Li K. Differential immune responses in pregnant patients recovered from COVID-19. Signal Transduct Target Ther. 2021 Jul 29;6(1):289. doi: 10.1038/s41392-021-00703-3. PMID: 34326311; PMCID: PMC8320317.

Study 766 – 14 cases from Italy

Asymptomatic or mild, but otherwise no clinical details (click here or study). Citation: De Biasi S, Tartaro DL, Gibellini L, Paolini A, Quong A, Petes C, Awong G, Douglas S, Lin D, Nieto J, Galassi FM, Borella R, Fidanza L, Mattioli M, Leone C, Neri I, Meschiari M, Cicchetti L, Iannone A, Trenti T, Sarti M, Girardis M, Guaraldi G, Mussini C, Facchinetti F, Cossarizza A. Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection. Nat Commun. 2021 Jul 29;12(1):4677. doi: 10.1038/s41467-021-24940-w. PMID: 34326336.

Study 765 – 5 cases from France

From author affiliations the patients were cared for at a l’Hopital Femme-M`ere-Enfant, Hospices Civils de Lyon, which has not previously reported cases (click here or study). Hower they may be included in study 150. Citation: Bouachba A, Allias F, Nadaud B, Massardier J, Mekki Y, Bouscambert Duchamp M, Fourniere B, Huissoud C, Trecourt A, Collardeau-Frachon S. Placental lesions and SARS-Cov-2 infection: Diffuse placenta damage associated to poor fetal outcome. Placenta. 2021 Jul 15;112:97-104. doi: 10.1016/j.placenta.2021.07.288. Epub ahead of print. PMID: 34329973; PMCID: PMC8280612.

26 July 2021 – study 764 added

Study 764 – 3,371 cases from UK

This MedRxiv preprint reports that compared with the first wave (wildtype SARS-CoV-2 predominant), pregnant women admitted to hospital during the 2nd wave (alpha variant predominant) had an increased risk of moderate or severe disease, aOR 1.75 (95% CI 1.48-2.06) (click here or study). Pregnant women admitted during the 3rd wave (delta predominant), had a further increase in risk, aOR 1.53 (1.07-2.17). No fully vaccinated pregnant women were admitted between 01/02/2021 when vaccination data collection commenced and 11/07/2021. This series includes cases from previous UKOSS reports studies 92, 533 and 667 as well as other UK series. Citation: Nicola Vousden, Rema Ramakrishnan, Kathryn Bunch, Edward Morris, Nigel Simpson, Christopher Gale, Patrick O’Brien, Maria Quigley, Peter Brocklehurst, Jennifer J Kurinczuk, Marian Knight. Impact of SARS-CoV-2 variant on the severity of maternal infection and perinatal outcomes: Data from the UK Obstetric Surveillance System national cohort. medRxiv 2021.07.22.21261000; doi: https://doi.org/10.1101/2021.07.22.21261000 [important]

24 July 2021 – studies 759 to 763 added

Study 763 – case report from Iran

From Shahid Beheshti University of Medical Sciences, Tehran (click here or study). Citation: Naseh A, Ashrafzadeh S. Possible Vertical Transmission From an Unsuspected SARS-CoV-2-Infected Mother to Her Newborn. Cureus. 2021 Jun 17;13(6):e15717. doi: 10.7759/cureus.15717. PMID: 34290917; PMCID: PMC8288625.

Study 762 – 56 cases from Italy

Cared for at “L. Sacco” University Hospital, Milan between March 7th and April 30th, 2020 (click here or study). The cases appear to overlap with study 312 and other series from Milan. Citation: Fenizia C, Saulle I, Di Giminiani M, Vanetti C, Trabattoni D, Parisi F, Biasin M, Savasi V. Unlikely SARS-CoV-2 Transmission During Vaginal Delivery. Reprod Sci. 2021 Jul 22. doi: 10.1007/s43032-021-00681-5. Epub ahead of print. PMID: 34296422.

Study 761 – 338 cases from Brazil

Collected by 16 maternity hospitals from the Brazilian network of COVID-19 during pregnancy (REde BRAsileira em estudos do COVID-19 em Obstetrícia REBRACO) up to July 2020 (click here or study). 29 mothers died. of whom 15 deaths were attributed to COVID-19. From author affiliations the hospitals were: Sao Paolo; University of Campinas, Faculdade de Medicina de Jundiaı´, Universidade Federal de São Carlos, Universidade Federal de São Paulo, Hospital Regional Jorge Rossmann Instituto So´crates Guanaes, Itanhae´m, Hospital Estadual Sumare´, Faculdade de Medicina da Universidade Estadual de São Paulo; plus Hospital das Clı´nicas de Porto Alegre, Maternidade UNIMED, Belo Horizonte, Universidade Federal do Ceara´, Fortaleza, Hospital Moinhos de Vento, Porto Alegre, Universidade Federal de Minas Gerais, Belo Horizonte, Instituto Fernandes Figueira, Rio de Janeiro, Universidade Federal de Pernambuco, Recife, Maternidade Clime´rio de Oliveira, Salvador, and Santa Casa de Miserico´rdia do Para´, Bele´m’. Likely overlap with other studies from Brazil. Citation: Costa ML, Souza RT, Pacagnella RC, Bento SF, Ribeiro-do-Valle CC, Luz AG, et al. (2021) Facing the COVID-19 pandemic inside maternities in Brazil: A mixed-method study within the REBRACO initiative. PLoS ONE 16(7): e0254977. https://doi.org/10.1371/journal.pone.0254977

Study 760 – 22 infected placentas from 7 countries

They were reviewed by a panel of pathologists (click here or study). Citation: Schwartz DA, Baldewijns M, Benachi A, Bugatti M, Bulfamante G, Cheng K, Collins RRJ, Debelenko L, De Luca D, Facchetti F, Fitzgerald B, Levitan D, Linn RL, Marcelis L, Morotti D, Morotti R, Patanè L, Prevot S, Pulinx B, Saad AG, Schoenmakers S, Strybol D, Thomas K, Tosi D, Toto V, van der Meeren LE, Verdijk RM, Vivanti AJ, Zaigham M. Hofbauer cells and coronavirus disease 2019 (COVID-19) in pregnancy: Molecular pathology analysis of villous macrophages, endothelial cells, and placental findings from 22 placentas infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with and without fetal transmission. Arch Pathol Lab Med. 2021 Jul 23. doi: 10.5858/arpa.2021-0296-SA. Epub ahead of print. PMID: 34297794.

Study 759 – Case report from USA

From Vassar Brothers Medical Center, Poughkeepsie, New York state (click here or study), so may be included in study 371. Citation: Abdulraheem, E, Shaikhoun, M, Kung, D. Severe peripartum cardiomyopathy complicated by COVID-19 infection and small intestinal obstruction. Clin Case Rep. 2021; 9:e04505. https://doi.org/10.1002/ccr3.4505

22 July 2021 – study 758 added

Study 758 – 88 cases from USA

Maternal and cord serology (click here or study). From author affiliations delivered at Weill Cornell Medicine, New York between April 18 and May 31, 2020. Likely overlap with studies 99, 118, 216, 230, 234, 276, 578 and 669. Citation: Kubiak JM, Murphy EA, Yee J, et al. Severe acute respiratory syndrome coronavirus 2 serology levels in pregnant women and their neonates. Am J Obstet Gynecol 2021;225:73.e1-7

21 July 2021 – studies 756 and 757 added

Study 757 – case report from the Slovak Republic

From author affiliations cared for at Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, which has not previously reported cases (click here or study). Citation: Kamil Biringer, Jana Sivakova, Juraj Marcinek, Terezia Pribulova, Tomas Rokos, Erik Kozubik, Erik Kudela, Lukas Plank. Placental pathology concerning sudden foetal demise in SARS-CoV-2 positive asymptomatic pregnant female. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021; 165:XX

Study 756 – 926 cases from COVI-preg

Collected by the approximately 81 centres, from 15 countries, participating in the COVI-Preg registry between March 24 and July 26, 2020 (click here or study). Click here for centres. Likely overlap with other series. Citation: Vouga, M., Favre, G., Martinez-Perez, O. et al. Maternal outcomes and risk factors for COVID-19 severity among pregnant women. Sci Rep 11, 13898 (2021). https://doi.org/10.1038/s41598-021-92357-y

20 July 2021 – study 755 added

Study 755 – case report from Spain

The patient had SARS-CoV-2 infection in the first trimester (click here or study). From author affiliations she was probably cared for at Hospital Clínico San Carlos de Madrid, so possibly also included in study 196. Citation: Fuentes Carrasco M, Mayoral Triana A, Cristóbal García IC, Pérez Pérez N, Izquierdo Méndez N, Soler Ruiz P, González González V. Catastrophic antiphospholipid syndrome during pregnancy. Eur J Obstet Gynecol Reprod Biol. 2021 Jul 7;264:21-24. doi: 10.1016/j.ejogrb.2021.07.002. Epub ahead of print. PMID: 34273751; PMCID: PMC8260489.

19 July 2021 – Study 754 added

Study 754 – 8,564 cases from ISARIC

This MedRxiv ISARIC (International Severe Acute Respiratory and emerging Infections Consortium) preprint of cases up to 25 May 2021, includes 8,564 pregnant women (click here or study). Collected by 1,651 sites across 63 countries. Citation: ISARIC Clinical Data Report issued: 14 July 2021. ISARIC Clinical Characterisation Group, Kenneth Baillie, … Laura Merson et al. medRxiv 2020.07.17.20155218; doi: https://doi.org/10.1101/2020.07.17.20155218

18 July 2021 – studies 751 to 753 added

Study 753, – 75 cases from Turkey

From Sanliurfa Training and Research Hospital between April and August 2020 (click here or study). This hospital has not previously reported cases. Citation: Damar Çakırca T, Torun A, Hamidanoğlu M, Portakal RD, Ölçen M, Çakırca G, Haksever M. COVID-19 infection in pregnancy: a single center experience with 75 cases. Ginekol Pol. 2021 Jul 15. doi: 10.5603/GP.a2021.0118. Epub ahead of print. PMID: 34263921.

Study 752 – 45 cases from Switzerland

This MedRxiv preprint reports participants of the Swiss COGEN Cohort study diagnosed between February and December 2020 at University Hospital Basel, University Hospital Zurich, University Hospital Bern, and the Cantonal Hospital Baden (click here or study). Being pregnant at the time of acute COVID-19 illness (OR 0.48 [0.23-1.01], p=0.054) was associated with lower odds of post COVID syndrome. Probable overlap with cases reported in studies 72, 310, 427 and 526. Citation: Caroline E. Gebhard, Claudia Sütsch, Susan Bengs, Manja Deforth, Karl Philipp Buehler, Nadia Hamouda, Alexander Meisel, Reto A. Schuepbach, Annelies S. Zinkernagel, Silvio D. Brugger, Claudio Acevedo, Dimitri Patriki, Benedikt Wiggli, Jürg H. Beer, Andrée Friedl, Raphael Twerenbold, Gabriela M. Kuster, Hans Pargger, Sarah Tschudin-Sutter, Joerg C. Schefold, Thibaud Spinetti, Arnaud Dussault-Cloutier, Chiara Henze, Mina Pasqualini, Dominik F. Sager, Lilian Mayrhofer, Mirjam Grieder, Janna Tontsch, Fabian Franzeck, Pedro D. Wendel Garcia, Daniel A. Hofmaenner, Thomas Scheier, Jan Bartussek, Leon Chrobok, David Stähli, Nicola Lott, Ahmed Haider, Muriel Grämer, Nidaa Mikail, Alexia Rossi, Nuria Zellweger, Petra Opic, Angela Portmann, Atanas Todorov, Aju P. Pazhenkottil, Michael Messerli, Ronny R. Buechel, Philipp A. Kaufmann, Valerie Treyer, Martin Siegemund, Ulrike Held, Vera Regitz-Zagrosek, Catherine Gebhard. Sex- and Gender-specific Risk Factors of Post-COVID-19 Syndrome: A Population-based Cohort Study in Switzerland. medRxiv 2021.06.30.21259757; doi: https://doi.org/10.1101/2021.06.30.21259757 [Long covid]

Study 751 – 107 cases from USA

From Columbia University Irving Medical Center – affiliated, New York Presbyterian (NYP), Morgan Stanley Children’s Hospital, and NYP Allen Pavilion Hospitals, New York, from 3/13/2020 (click here or study). Likely overlap with other studies from these hospitals. See also indirect effects, Paper 77 (click here). Citation: Lauren C. Shuffrey, Morgan R. Firestein, Margaret Kyle, Andrea Fields, Carmela Alcantara, Dima Amso, Judy Austin, Jennifer M. Bain, Jennifer Barbosa, Mary Bence, Catherine Bianco, Cristina Fernandez, Sylvie Goldman, Cynthia Gyamfi-Bannerman, Violet Hott, Yunzhe Hu, Maha Hussain, Pam Factor-Litvak, Maristella Lucchini, Arthur Mandel, Rachel Marsh, Danielle McBrian, Mirella Mourad, Rebecca Muhle, Kimberly Noble, Anna A. Penn, Cynthia Rodriguez, Ayesha Sania, Wendy G. Silver, Kally C. O Reilly, Melissa Stockwell, Nim Tottenham, Martha G. Welch, Noelia Zork, William P. Fifer, Catherine Monk, Dani Dumitriu. Birth during the COVID-19 pandemic, but not maternal SARS-CoV-2 infection during pregnancy, is associated with lower neurodevelopmental scores at 6-months medRxiv 2021.07.12.21260365; doi: https://doi.org/10.1101/2021.07.12.21260365

12 July 2021 – studies 747 to 750 added

Study 750 – 58 cases from India

Cared for between June and September 2020 at Bharati Vidyapeeth hospital, in Pune, which has not previously reported cases (click here or study). One mother died. Citation: Malshe N, Patnaik SK, Lalwani S, Suryawanshi P, Kulkarni R, Mhaske S, Mishra AC, Arankalle V. Perinatal transmission of SARS-CoV-2 and transfer of maternal IgG/neutralizing anti-SARS-CoV-2 antibodies from mothers with asymptomatic infection during pregnancy. Infection. 2021 Jul 7:1–7. doi: 10.1007/s15010-021-01650-5. Epub ahead of print. PMID: 34232457; PMCID: PMC8262126.

Study 749 – 42 cases from Iran

From the hospitals of Shahid Beheshti University of Medical Sciences, Tehran between 21 February and 30 November 2020, so likely overlap with study 514 (click here or study). Two mothers died. Citation: Hosseini MS, Hosseini A, Ghaffari E, Radfar M, Shirvani F, Tabatabai S, Abtahi D, Mirhadi M, Mortazavi M, Ariana S. Evaluation of clinical outcomes of neonates born to mothers with coronavirus (COVID-19) in Shahid Beheshti Hospitals. J Educ Health Promot. 2021 May 31;10(1):173. doi: 10.4103/jehp.jehp_20_21. PMID: 34250107; PMCID: PMC8249960.

Study 748 – 65 cases from India

From Sarojini Naidu Medical College, Agra, Uttar Pradesh, which has not previously reported cases, between April 15 and June 30, 2020 (click here or study). Citation: Agarwal N, Garg R, Singh S, Agrawal A. Coronavirus disease 2019 in pregnancy: Maternal and perinatal outcome. J Educ Health Promot. 2021 May 31;10(1):194. doi: 10.4103/jehp.jehp_954_20. PMID: 34250128; PMCID: PMC8249977.

Study 747 – 70 women with past SARS-CoV-2 infection undergoing assisted conception in China

Fourteen conceived, which was similar to the rate among those without past infection (click here or study). From Tongji Hospital, Wuhan between May 2020 and February 2021. Citation: Wang M, Yang Q, Ren X, Hu J, Li Z, Long R, Xi Q, Zhu L, Jin L. Investigating the impact of asymptomatic or mild SARS-CoV-2 infection on female fertility and in vitro fertilization outcomes: A retrospective cohort study. EClinicalMedicine. 2021 Aug;38:101013. doi: 10.1016/j.eclinm.2021.101013. Epub 2021 Jul 6. PMID: 34250457; PMCID: PMC8259363.

10 July 2021 – study 697 citation updated.

9 July 2021 – study 746 added

Study 746 – 1,530 cases from India

From Nair hospital in Mumbai between 1 April 2020 and 14 May 2021, so overlap with previous cases from that hospital (click here or study. Appendix here). 30 mothers died, with maternal mortality, ICU admission and severity significantly higher during the 2nd wave. Citation: Mahajan, Niraj N. MD; Pophalkar, Madhura MS; Patil, Sarika MPhil; Yewale, Bhagyashree MBBS; Chaaithanya, Itta Krishna PhD; Mahale, Smita D. PhD; Gajbhiye, Rahul K. MBBS, PhD Pregnancy Outcomes and Maternal Complications During the Second Wave of Coronavirus Disease 2019 (COVID-19) in India, Obstetrics & Gynecology: July 7, 2021 – Volume – Issue – 10.1097/AOG.0000000000004529
doi: 10.1097/AOG.0000000000004529

8 July 2021 – studies 743 to 745 added

Study 745 – 217 cases from Turkey

Cared for in an unnamed tertiary medical centre between 1 March and 30 November 2020 (click here or study). Citation: Bozkurt F, Çoşkun Ö, Yeleç S, Bekçibaşi M, Asena M, Bağli I. Comparison of the Clinical and Laboratory Findings in COVID-19 Positive Pregnants without Comorbidity. Turk J Med Sci. 2021 Jul 8. doi: 10.3906/sag-2105-116. Epub ahead of print. PMID: 34233388.

Study 744 – 17 maternal deaths in UK

The second MBRRACE report (July 2021) includes ten pregnant or recently pregnant women who died from Covid-19, four who died from other causes with SARS-CoV-2 infection, and three whose deaths were indirectly caused by the pandemic (click here or study). This report covers 01/06/2020 to 31/03/2021, and therefore excludes cases in the previous MBRRACE report (study 255). Citation: Knight M, Bunch K, Cairns A, Cantwell R, Cox P, Kenyon S, Kotnis R, Lucas DN, Lucas S, Nelson-Piercy C, Patel R, Rodger A, Shakespeare J, Tuffnell D, Kurinczuk JJ on behalf of MBRRACE-UK. Saving Lives, Improving Mothers’ Care Rapid Report 2021: Learning from SARS-CoV-2-related and associated maternal deaths in the UK June 2020-March 2021. Oxford: National Perinatal Epidemiology Unit, University of Oxford 2021. ISBN: 978-1-8383678-2-4

Study 743 – 426 cases admitted to ICU in UK

The 5 July 2021 ICNARC report (click here or study). Pregnancy p74. Thirteen pregnant or recently pregnant woman have died. Citation: Intensive Care National Audit & Research Centre. ICNARC report on COVID-19 in critical care: England, Wales and Northern Ireland 5 July 2021 Accessed 8 July 2021. https://www.icnarc.org/Our-Audit/Audits/Cmp/Reports

7 July 2021 – Studies 738 and 742 added

Study 742 – 11,247 cases from Brazil

1,031 of the mothers died (click here or study). Collected by the Obstetric Observatory, so overlap with study 724, and many other series from Brazil. Citation: Francisco RPV, Lacerda L, Rodrigues AS. Obstetric Observatory BRAZIL – COVID-19: 1031 maternal deaths because of COVID-19 and the unequal access to health care services. Clinics (Sao Paulo). 2021 Jun 28;76:e3120. doi: 10.6061/clinics/2021/e3120. PMID: 34190858; PMCID: PMC8221555.

Study 741 – 16 possible cases from Kenya

(click here or study [no pdf available]). Citation: Otieno NA, Azziz-Baumgartner E, Nyawanda BO, Oreri E, Ellington S, Onyango C, et al. SARS-CoV-2 infection among pregnant and postpartum women, Kenya, 2020–2021. Emerg Infect Dis. 2021 Sep [date cited]. https://doi.org/10.3201/eid2709.210849

Study 740 – 1,295 cases from Spain

Recruited by the Spanish Obstetrics Emergency Group between 1 March and 3 November 2020, so included in many previous studies (click here or study). Citation: Cuñarro-López Y, Pintado-Recarte P, Hernández-Martín C, Paya-Martínez P, López-Pérez R, Cueto-Hernández I, Ruiz-Labarta J, Cano-Valderrama Ó, Martínez-Pérez Ó, Bravo-Arribas C, Ortega MA, De León-Luis JA. Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the Pandemic. J Pers Med. 2021 Jun 25;11(7):599. doi: 10.3390/jpm11070599. PMID: 34201923.

Study 739 – maternal mortality ratio in Mexico in 2021

The MMR increased from expected, 29.8 per 100,000, to observed 47.2 per 100,000 (click here or study). A 60% increase compared with the pre-pandemic trend. 309 deaths were directly caused by Covid. Citation: Mendez-Dominguez, N., Santos-Zaldívar, K., Gomez-Carro, S. et al. Maternal mortality during the COVID-19 pandemic in Mexico: a preliminary analysis during the first year. BMC Public Health 21, 1297 (2021). https://doi.org/10.1186/s12889-021-11325-3 important

Study 738 – 7 cases from China

Pregnant women with COVID-19 from January 28 to February 28, 2020, at Tongji and Union Hospital, Huazhong University of Science and Technology, Wuhan. (click here or study). This is grid.412793.a, so these cases have been reported many times before. Citation: Liang Dong, Shiyao Pei, Qin Ren, Shuxiang Fu, Liang Yu, Hui Chen, Xiang Chen, Mingzhu Yin, Evaluation of vertical transmission of SARS-CoV-2 in utero: Nine pregnant women and their newborns, Placenta, Volume 111, 2021, Pages 91-96, ISSN 0143-4004, https://doi.org/10.1016/j.placenta.2021.06.007. (https://www.sciencedirect.com/science/article/pii/S0143400421001806)

5 July 2021 – studies 735 to 737 added

Study 737 – 725 cases and 1,459 controls collected by the Intercovid group

A slightly expanded, and different analysis, of the cases in study 683 (click here or study). Citation: Papageorghiou AT, Deruelle P, Gunier RB, et al. Preeclampsia and COVID-19: results from the INTERCOVID prospective longitudinal study [published online ahead of print, 2021 Jun 26]. Am J Obstet Gynecol. 2021;S0002-9378(21)00561-5. doi:10.1016/j.ajog.2021.05.014

Study 736 – 12,566 severe cases from Brazil

Pregnancy cases and non-pregnant control women with severe Covid-19 collected by the Brazilian ARDS Surveillance System (click here or study). Likely overlap with many previous reports from that registry. Citation: Scheler, C.A., Discacciati, M.G., Vale, D.B., Lajos, G.J., de Castro Surita, F. and Teixeira, J.C. (2021), Mortality in pregnancy and the postpartum period in women with severe acute respiratory distress syndrome related to COVID-19 in Brazil, 2020. International Journal of Gynecology & Obstetrics. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13804

Study 735 – case report from Romania

From Premiere Hospital, Timişoara, which has not previously reported cases (click here or study). Citation: Popescu, D.E.; Cioca, A.; Muresan, C.; Navolan, D.; Gui, A.; Pop, O.; Marcovici, T.; Ilie, C.; Craina, M.; Boia, M. A Case of COVID-19 Pregnancy Complicated with Hydrops Fetalis and Intrauterine Death. Medicina 2021, 57, 667. https://doi.org/10.3390/medicina57070667

1 July 2021 – studies 733 and 734 added

Study 734 – 16 cases from Israel

From E. Wolfson Medical Center, in Holon, which has not previously reported cases (click here or study). Citation: Barber, E.; Kovo, M.; Leytes, S.; Sagiv, R.; Weiner, E.; Schwartz, O.; Mashavi, M.; Holtzman, K.; Bar, J.; Engel, A.; Ginath, S. Evaluation of SARS-CoV-2 in the Vaginal Secretions of Women with COVID-19: A Prospective Study. J. Clin. Med. 2021, 10, 2735. https://doi.org/10.3390/jcm10122735

Study 733 – 40 cases from Greece

From Alexandra Maternity Hospital, Athens, which has not previously reported cases (click here or study). No mothers required intensive care and no mothers or babies died. Citation: Antsaklis P, Tasias K, Psarris A, Theodora M, Daskalakis G, Rodolakis A. Covid-19 and pregnancy: the experience of a tertiary maternity hospital. J Perinat Med. 2021 Jun 29. doi: 10.1515/jpm-2021-0070. Epub ahead of print. PMID: 34187133.

29 June 2021 – studies 731 and 732 added

Study 732 – 62 cases from Indonesia

From Universitas Airlangga Hospital, Surabaya, between April & August 2020 (click here or study). Six mothers and five babies died. This hospital has not previously reported cases. Citation: Muhammad Ilham Aldika Akbar, Khanisyah Erza Gumilar, Rino Andriya, Manggala Pasca Wardhana, Pungky Mulawardhana, Jimmy Yanuar Anas, Ernawati, Muhammad Ardian Cahya Laksana, Gustaaf Dekker. Clinical Manifestations and Pregnancy Outcomes of Covid-19 in Indonesian Referral Hospital in Central Pandemic Area medRxiv 2021.06.20.21259219; doi: https://doi.org/10.1101/2021.06.20.21259219

Study 731 – 94 first trimester cases from USA

Selected from the PRIORITY registry (click here or study). Likely overlap with other US cases. Citation: JACOBY VL, MURTHA A, AFSHAR Y, GAW S, ASIODU I, TOLOSA J, NORTON ME, BOSCARDIN J, FLAHERMAN V, Risk of Pregnancy Loss Prior to 20 weeks Gestation with COVID-19, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.06.080.

26 June 2021 – study 730 added

Study 730 – 24 cases from Germany

From author affiliations, treated in University Medical Centre Hamburg-Eppendorf, Hamburg which has not previously reported cases (click here or study). Clinical details in supplementary material here. Citation: Tallarek AC, Urbschat C, Fonseca Brito L, Stanelle-Bertram S, Krasemann S, Frascaroli G, Thiele K, Wieczorek A, Felber N, Lütgehetmann M, Markert UR, Hecher K, Brune W, Stahl F, Gabriel G, Diemert A, Arck PC. Inefficient Placental Virus Replication and Absence of Neonatal Cell-Specific Immunity Upon Sars-CoV-2 Infection During Pregnancy. Front Immunol. 2021 Jun 3;12:698578. doi: 10.3389/fimmu.2021.698578. PMID: 34149740; PMCID: PMC8211452.

24 June 2021 – studies 725 to 729 added

Study 729 – 195 cases from USA

From the University of Maryland health care system in Baltimore (click here or study). Probable overlap with studies 269, 418 and 669. Citation: Liviu Cojocaru, Myint Noe, Autusa Pahlavan, Alissa Werzen, Hyunuk Seung, Young Chae Jessica Yoo, Patricia Tyson, Shivakumar Narayanan, Shifa Turan, Ozhan M. Turan, Joel V. Chua. Increased Risk of Severe COVID-19 Disease in Pregnancy in a Multicenter Propensity Score-Matched Study. medRxiv 2021.06.18.21258899; doi: https://doi.org/10.1101/2021.06.18.21258899

Study 728 – 55 cases from Iran

From Shahid Mohammadi Hospital, Bandar Abbas, Hormozgan, which has not previously reported cases, between March to November 2020 (click here or study). Citation: Taghavi SA, Heidari S, Jahanfar S, Amirjani S, Aji-Ramkani A, Azizi-Kutenaee M, Bazarganipour F. Obstetric, maternal, and neonatal outcomes in COVID-19 compared to healthy pregnant women in Iran: a retrospective, case-control study. Middle East Fertil Soc J. 2021;26(1):17. doi: 10.1186/s43043-021-00059-2. Epub 2021 Jun 14. PMID: 34149282; PMCID: PMC8202219.

Study 727 – 43 cases from Spain

Collected by the nine hospitals of the GESTACOVID Collaborative Group (click here or study). These are Vall d’Hebron , Barcelona; La Paz, Madrid; Hospital Virgen de la Arrixaca, Murcia; Hospital Universitario Cruces, Bizkaia; Hospital Clínico Universitario Lozano Blesa, Zaragoza; Hospital de Torrejón, Madrid; Hospital Universitario San Cecilio, Granada; Hospital Universitario La Fe, Valencia; and Hospital Universitario Príncipe de Asturias, Madrid. Likely overlap with other Spanish series. Citation: Garcia-Ruiz I, Sulleiro E, Serrano B, Fernandez-Buhigas I, Rodriguez-Gomez L, Sanchez-Nieves D, Anton-Pagarolas A, Esperalba-Esquerra J, Frick MA, Camba F, Navarro-Jimenez A, Fernandez-Hidalgo N, Maiz N, Carreras E, Suy A, GESTACOVID Collaborative Group, Congenital infection of SARS-CoV-2 in live-born neonates: a population-based descriptive study, Clinical Microbiology and Infection, https://doi.org/10.1016/j.cmi.2021.06.016.

Study 726 – 31,253 cases from Mexico

The last of these weekly reports for 2020 from Mexico. 205 women had died (click here or study). [In Spanish] Overlap with study 722. Citation: Health Secretary General Directorate of Epidemiology Epidemiological reports of pregnant and postpartum women studied, suspected of COVID 19 February 22, 2021. Weekly publication by the Directorate of Epidemiological Surveillance of Noncommunicable Diseases. https://www.gob.mx/salud/documentos/informes-epidemiologicos-de-embarazadas-y-puerperas-estudiadas-ante-sospecha-de-covid-19. Accessed 24 June 2021

Study 725 – 104 cases from South Africa

From Ekurhuleni Heath District which includes Johannesburg and Pretoria (click here or study). Six women died. Citation: Jayati Kusari Basu, Lawrence Chauke & Terrance Magoro (2021): Maternal mortality from COVID 19 among South African pregnant women, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2021.1902501

20 June 2021 – studies 723 and 724 added

Study 724 – 10,349 cases from Brazil

The Brazilian Obstetric Observatory included 10,349 pregnant or postnatal women with Covid-19 on 20 June 2021 (click here). 2,281 (16.2%) had died. Citation: Rodrigues A, Lacerda L, Francisco, RPV. ‘Brazilian Obstetric Observatory’ arXiv preprint arXiv:2105.06534 (2021). https://observatorioobstetrico.shinyapps.io/covid_gesta_puerp_br/ Accessed 20 June 2021 Important

Study 723 – methods used by Brazilian Obstetric Observatory

This arXiv preprint includes no primary data but provides background methodology for study 724 (click here or study). Citation: Rodrigues, A. and Lacerda, L. and Francisco, RPV ‘Brazilian Obstetric Observatory’ arXiv preprint arXiv:2105.06534 (2021).

19 June update – studies 720 to 722 added

Study 722 – 220 maternal deaths in Mexico

There were 220 maternal deaths from Covid-19 in Mexico in 2020 (click here or study). Citation: General Directorate of Epidemiology. Informes Semanales para la Vigilancia Epidemiológica de Muertes Maternas 2020. https://www.gob.mx/salud/documentos/informes-semanales-parala-vigilancia-epidemiologica-de-muertes-maternas-2020. Accessed June 19 2021

Study 721 – 36 cases from UK

Collected as part of the Coagulopathy Associated with COVID-19 [CA-COVID-19] study from 12 NHS Trusts between 1st of March and 31st May 2020 (click here or study). Likely overlap with many previous UK series. Citation: Crossette-Thambiah C, Nicholson P, Rajakaruna I, Langridge A, Sayar Z, Perelta MR, Essex S, Oakes R, Mounter P, Lewis S, Dutt T, Scott I, Aung N, Shapiro S, Laffan M, Arachchillage DR. The clinical course of COVID-19 in pregnant versus non-pregnant women requiring hospitalisation: results from the multicentre UK CA-COVID-19 study. Br J Haematol. 2021 Jun 16. doi: 10.1111/bjh.17579. Epub ahead of print. PMID: 34132386.

Study 720 – case report from Germany

A woman with SARS-CoV-2 antibodies, but PCR negative, gave birth to a moderately preterm infant with intracranial bleeding and periventricular leukomalacia as a potential consequence of post-COVID-19 hyperinflammation during pregnancy (click here or study). From author affilation cared for in University Hospital of Würzburg, which has not previously reported cases. Citation: Engert V, Siauw C, Stock A, Rehn M, Wöckel A, Härtel C, Wirbelauer J. Severe Brain Damage in a Moderate Preterm Infant as Complication of Post-COVID-19 Response during Pregnancy. Neonatology. 2021 Jun 14:1-4. doi: 10.1159/000516846. Epub ahead of print. PMID: 34126613.

14 June update – study 719 added

Study 719 – Case report from UK or Ireland

From author affiliations the patient was likely cared for either in Birmingham, UK, or Limerick, Republic of Ireland (click here or study). Citation: Marton T, Hargitai B, Hunter K, Pugh M, Murray P. Massive Perivillous Fibrin Deposition and Chronic Histiocytic Intervillositis a Complication of SARS-CoV-2 Infection. Pediatr Dev Pathol. 2021 Jun 3:10935266211020723. doi: 10.1177/10935266211020723. Epub ahead of print. PMID: 34082613.

13 June update – studies 716 to 718 added

Study 718 – 19 maternal deaths in Brazil

An analysis of maternal deaths and live births in the state of Bahia, from January 1, 2011, to December 31, 2020 (click here or study). The 19 maternal deaths in 2020, which mentioned Covid, may underestimate those caused directly or indirectly by the disease. Citation: de Carvalho-Sauer RCO, Costa MDCN, Teixeira MG, do Nascimento EMR, Silva EMF, Barbosa MLA, da Silva GR, Santos TP, Paixao ES. Impact of COVID-19 pandemic on time series of maternal mortality ratio in Bahia, Brazil: analysis of period 2011-2020. BMC Pregnancy Childbirth. 2021 Jun 10;21(1):423. doi: 10.1186/s12884-021-03899-y. PMID: 34112099. Important

Study 717 – 253 cases from Panama

From the following five hospitals, Complejo Hospitalario “Dr. AAM” Social Security Fund, Santo Tomás
Hospital, José Domingo de Obaldía Hospital in Chiriquí, Luis “Chico” Fábrega Hospital in Veraguas, and San Miguel Arcángel Hospital, none of which have previously reported cases (click here or study). The first report from Panama. Citation: Jaime Sánchez, Jorge Espinosa, Luis Carlos Caballero, B Sara Campana, Arelys Quintero, Carlos Luo, C Jorge Ng, Rafael de Gracia, Paulino Vigil-De Gracia. NEW CORONAVIRUS IN PREGNANT WOMEN. Maternal and perinatal outcomes medRxiv 2021.06.03.21258328; doi: https://doi.org/10.1101/2021.06.03.21258328

Study 716 – 418 cases from Denmark

Collected by the Danish National Patient Register and Danish Microbiology Database between March 1 and October 31, 2020 (click here or study). Citation: Anna JM Aabakke, Lone Krebs, Tanja G Petersen, Frank S Kjeldsen, Giulia Corn, Karen Wøjdemann, Mette H Ibsen, Fjola Jonsdottir, Elisabeth Rønneberg, Charlotte S Andersen, Iben Sundtoft, Tine Clausen, Julie Milbak, Lars Burmester, Birgitte Lindved, Annette Thorsen-Meyer, Mohammed R Khalil, Birgitte Henriksen, Lisbeth Jønsson, Lise LT Andersen, Kamilla K Karlsen, Monica L Pedersen, Åse Klemmensen, Marianne Vestgaard, Dorthe Thisted, Manrinder K Tatla, Line S Andersen, Anne-Line Brülle, Arense Gulbech, Charlotte B Andersson, Richard Farlie, Lea Hansen, Lone Hvidman, Anne N Sørensen, Sidsel L Rathcke, Katrine H Rubin, Lone K Petersen, Jan S Jørgensen, Lonny Stokholm, Mette Bliddal. SARS-CoV-2 infection in pregnancy in Denmark – characteristics and outcomes after confirmed infection in pregnancy: a nationwide, prospective, population-based cohort study. medRxiv 2021.06.08.21258480; doi: https://doi.org/10.1101/2021.06.08.21258480 Important. [Control group]

12 June update – study 715 added

Study 715 – 514 cases from India

524 livebirths from 514 mothers, including 8 twins and one triplet pregnancy, collected by the National Registry of pregnant women with COVID-19 in India (PregCovid registry) (click here or study). The hospitals are not named and cases likely overlap with other series from India. Citation: Sushma Malik, MD, Suchitra Surve, MD, Poonam Wade, MD, Santosh Kondekar, MD, Vishal Sawant, MD, Murtuja Shaikh, MD, Periyasamy Kuppusamy, PhD, Ramesh Bharmal, MD, Smita D Mahale, PhD, Deepak N Modi, PhD, Rahul K Gajbhiye, MBBS, PhD, Clinical characteristics, management, and short term outcome of neonates born to mothers with COVID-19 in a tertiary care hospital in India, Journal of Tropical Pediatrics, 2021;, fmab054, https://doi.org/10.1093/tropej/fmab054

7 June update – studies 713 and 714 added

Study 714 – 65 cases from Israel

From eight hospitals, so likely overlap with other Israeli studies (click here or study). Compared with 86 vaccinated pregnant women -see vaccine source 39. Citation: Beharier O, Plitman Mayo R, Raz T, Nahum Sacks K, Schreiber L, Suissa-Cohen Y, Chen R, Gomez-Tolub R, Hadar E, Gabbay-Benziv R, Jaffe Moshkovich Y, Biron-Shental T, Shechter-Maor G, Farladansky-Gershnabel S, Yitzhak Sela H, Benyamini-Raischer H, Sela ND, Goldman-Wohl D, Shulman Z, Many A, Barr H, Yagel S, Neeman M, Kovo M. Efficient maternal to neonatal transfer of antibodies against SARS-CoV-2 and BNT162b2 mRNA COVID-19 vaccine. J Clin Invest. 2021 May 20:150319. doi: 10.1172/JCI150319. Epub ahead of print. PMID: 34014840.

Study 713 – 68 cases from Bangladesh

These women were treated at Dhaka Medical College Hospital from March 15, to August 15, 2020 (click here or study). Two mothers died. This hospital, which disambiguates as Dhaka Medical College and Hospital grid.413674.3, has not previously reported cases. Citation: S. K. Jakaria Been Sayeed, Md. Mujibur Rahman, A. K. M. Humayon Kabir, Md. Moniruzzaman, Reaz Mahmud, Mohammad Abdullah Yusuf, Sabrina Rahman. Clinical, Laboratory Characteristics and Pregnancy Outcome of COVID-19 Patients Admitted in the Largest COVID Dedicated Hospital of Bangladesh. American Journal of Internal Medicine. Vol. 9, No. 1, 2021, pp. 11-16. doi: 10.11648/j.ajim.20210901.12 Cautionary noteAmerican Journal of Internal Medicine is not on PubMed, but is listed as a predatory journal on Beall’s list. The publisher Science Publishing Group has an address in New York City but is actually based in Pakistan (click here).

6 June update – studies 710 to 712 added

Study 712 – 1,347 cases from Spain

Collected by the 78 centers of the Spanish Obstetric Emergency Group between 26 February and 5 November 2020 (click here or study). Includes both the second wave in Spain, and a control group of unaffected women. Likely overlap with many other reports from Spain. Citation: Cruz Melguizo S, de la Cruz Conty ML, Carmona Payán P, Abascal-Saiz A, Pintando Recarte P, González Rodríguez L, Cuenca Marín C, Martínez Varea A, Oreja Cuesta AB, Rodríguez PP, Fernández Buhigas I, Rodríguez Gallego MV, Fernández Alonso AM, López Pérez R, Broullón Molanes JR, Encinas Pardilla MB, Ramírez Gómez M, Gimeno Gimeno MJ, Sánchez Muñoz A, Martínez-Pérez O, On Behalf Of The Spanish Obstetric Emergency Group S O E G. Pregnancy Outcomes and SARS-CoV-2 Infection: The Spanish Obstetric Emergency Group Study. Viruses. 2021 May 7;13(5):853. doi: 10.3390/v13050853. PMID: 34067086; PMCID: PMC8151603. [important]

Study 711 – five cases from Indonesia

From Cipto Mangunkusumo General Hospital, Jakarta, and treated with remdesivir (click here or study). This hospital has not previously reported cases. Citation: Saroyo YB, Rumondang A, Febriana IS, Harzif AK, Irwinda R. Remdesivir Treatment for COVID 19 in Pregnant Patients with Moderate to Severe Symptoms: Serial Case Report. Infect Dis Rep. 2021 May 17;13(2):437-443. doi: 10.3390/idr13020042. PMID: 34067822; PMCID: PMC8162322.

Study 710 – 14 cases from Turkey

From Gungoren Hospital, Istanbul, which has not previously reported cases (click here or study). Citation: Yaman A, Kandemir I, Varkal MA. Infants infected with SARS-CoV-2 and newborns born to mother diagnosed with COVID-19: clinical experience. Ir J Med Sci. 2021 Jun 1:1–6. doi: 10.1007/s11845-021-02662-8. Epub ahead of print. PMID: 34075529; PMCID: PMC8169398.

5 June update – studies 708 and 709 added

Study 709 – 64 cases from Italy

From Sacco Hospital and Buzzi Hospital in Milan, and at San Gerardo Hospital in Monza between March and August 2020 (click here or study). The cases are likely included in the various Lomabardy series. Citation: Chiara Tasca, Roberta Simona Rossi, Silvia Corti, Gaia Maria Anelli, Valeria Savasi, Federica Brunetti, Manuela Cardellicchio, Emilio Caselli, Cristina Tonello, Patrizia Vergani, Manuela Nebuloni, Irene Cetin, Placental pathology in COVID-19 affected pregnant women: A prospective case-control study. Placenta, Volume 110, 2021, Pages 9-15, ISSN 0143-4004, https://doi.org/10.1016/j.placenta.2021.04.002. (https://www.sciencedirect.com/science/article/pii/S0143400421001132)

Study 708 – 55 cases from Israel

These first and second trimester cases were treated at Sheba Medical Center, Tel-Hashomer, between March 2020 and February 2021 (click here or study). Possible overlap with studies 330 and 449. Citation: Rosen H, Bart Y, Zlatkin R, Ben-Sira L, Ben Bashat D, Amit S, Cohen C, Regev-Yochay G, Yinon Y. Fetal and Perinatal Outcome Following First and Second Trimester COVID-19 Infection: Evidence from a Prospective Cohort Study. J Clin Med. 2021 May 16;10(10):2152. doi: 10.3390/jcm10102152. PMID: 34065646; PMCID: PMC8156528.

29 May update – studies 706 and 707 added

Study 707 – 120 cases from Palestine

Collected by the Palestine Ministry of Health (click here or study). One mother died. The first reported cases from Palestine. Citation: Maraqa B, Al-Shakhra K, Alawneh M, Jallad R, Alkaila M. Demographic factors associated with COVID-19-related death in Palestine. Public Health Pract (Oxf). 2021 Nov;2:100145. doi: 10.1016/j.puhip.2021.100145. Epub 2021 May 18. PMID: 34027510; PMCID: PMC8129786.

Study 706 – 288 cases from Saudi Arabia

From King Fahad Medical City, Al-Yammamah, and Imam Abdulrahman Al-Faisal hospitals in Riyadh between March and November 2020 (click here or study). One mother and four babies died. This series likely includes cases in studies 554 and 608. Citation: Al-Matary A, Almatari F, Al-Matary M, AlDhaefi A, Alqahtani MHS, Alhulaimi EA, AlOtaiby S, Almehiny K, John LS, Alanazi FS, Azad A, Aldandan FK. Clinical outcomes of maternal and neonate with COVID-19 infection – Multicenter study in Saudi Arabia. J Infect Public Health. 2021 Apr 20;14(6):702-708. doi: 10.1016/j.jiph.2021.03.013. Epub ahead of print. PMID: 34020209; PMCID: PMC8056848.

28 May update – study 705 added

Study 705 – 28 pregnant women in Recovery immune plasma trial

Tewnty eight pregnant women participated in the UK Recovery convalescent plasms trial (click here or study). Their group allocation was not reported. Citation: RECOVERY Collaborative Group. Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial. Lancet. 2021 May 14:S0140-6736(21)00897-7. doi: 10.1016/S0140-6736(21)00897-7. Epub ahead of print. PMID: 34000257; PMCID: PMC8121538.

27 May update – study 704 added

Study 704 – 52 cases from Japan

A web-survey of 624 hospitals in Japan identified 52 newborns born to mothers with confirmed SARS-CoV-2 infection (click here or study). One newborn tested positive. Citation: Morioka I, Toishi S, Kusaka T, Wada K, Mizuno K; committee of neonatal medicine in Japan Pediatric Society. Medical care of newborns born to mothers with confirmed or suspected severe acute respiratory syndrome coronavirus 2 infections in Japan. Pediatr Int. 2021 May 27. doi: 10.1111/ped.14855. Epub ahead of print. PMID: 34041810.

24 May update – studies 702 and 703 added

Study 703 – 198 cases from Spain

From author affiliations collected by 11 pathology departments in Barcelona (click here or study). Probably overlap with studies 140, 185, 191, 235, 413, 417, 607, 635, and 695. Citation: Garrido-Pontnou, M., Navarro, A., Camacho, J. et al. Diffuse trophoblast damage is the hallmark of SARS-CoV-2-associated fetal demise. Mod Pathol (2021). https://doi.org/10.1038/s41379-021-00827-5

Study 702 – 7,950 cases from USA

Collected by the SET-NET consortium (click here or study). Citation: Romeo R Galang, Suzanne M Newton, Kate R Woodworth, Isabel Griffin, Titilope Oduyebo, Christina L Sancken, Emily O’Malley Olsen, Kathryn Aveni, Heather Wingate, Hanna Shephard, Chris Fussman, Zahra S Alaali, Kristin Silcox, Samantha Siebman, Umme-Aiman Halai, Camille Delgado Lopez, Mamie Lush, Ayomide Sokale, Jerusha Barton, Ifrah Chaudhary, Paul H Patrick, Levi Schlosser, Bethany Reynolds, Nicole Gaarenstroom, Sarah Chicchelly, Jennifer S Read, Leah de Wilde, Deborah Mbotha, Eduardo Azziz-Baumgartner, Aron J Hall, Van T Tong, Sascha Ellington, Suzanne M Gilboa, CDC COVID-19 Response Pregnancy and Infant Linked Outcomes Team, Risk factors for illness severity among pregnant women with confirmed SARS-CoV-2 infection – Surveillance for Emerging Threats to Mothers and Babies Network, 22 state, local, and territorial health departments, March 29, 2020 -March 5, 2021, Clinical Infectious Diseases, 2021;, ciab432, https://doi.org/10.1093/cid/ciab432

21 May update – study 701 added

Study 701 – 3,527 cases from UK

3,527 women who gave birth between 29th May 2020 and 31st 29 January 2021, and had a positive SARS-Cov-2 test, were compared with 338,553 women giving birth without (click here or study). They were identified using Hospital Episode Statistics, and will therefore overlap with UKOSS and most other UK reports over this time period. Citation: Ipek GUROL-URGANCI, Jennifer E. JARDINE, Fran CARROLL, Tim DRAYCOTT, George DUNN, Alissa FREMEAUX, Tina HARRIS, Jane HAWDON, Edward MORRIS, Patrick MULLER, Lara WAITE, Kirstin WEBSTER, Jan VAN DER MEULEN, Asma KHALIL. Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection at the time of birth in England: national cohort study. American Journal of Obstetrics and Gynecology,
2021. ISSN 0002-9378, https://doi.org/10.1016/j.ajog.2021.05.016. (https://www.sciencedirect.com/science/article/pii/S0002937821005652)
[important]

17 May update – study 700 added

Study 700 – 73 cases from USA

From MedStar Washington Hospital Center, Washington, District of Columbia. (click here or study). Citation: Chornock R, Iqbal SN, Wang T, Kodama S, Kawakita T, Fries M. Incidence of Hypertensive Disorders of Pregnancy in Women with COVID-19. Am J Perinatol. 2021 May 3. doi: 10.1055/s-0041-1727167. Epub ahead of print. PMID: 33940651.

16 May update – studies 697 to 699 added. Study 533 updated

Study 699 – 20 cases from China

From Tongji Hospital in Wuhan between January 19 to April 20, 2020 (click here or study). Likely previously reported many times. Citation: Chen G, Liao Q, Ai J, Yang B, Bai H, Chen J, Liu F, Cao Y, Liu H and Li K (2021) Immune Response to COVID-19 During Pregnancy. Front. Immunol. 12:675476. doi: 10.3389/fimmu.2021.675476

Study 698 – 8,248 cases from Brazil

From the Brazilian official severe acute respiratory syndrome (SARS) surveillance system (click here or study). 803 mothers died. Likely overlap with studies 66, 138, 194, 201, 203, 248, 249 and 309. Citation: Maíra L S Takemoto, Marcos Nakamura-Pereira, Mariane O Menezes, Leila Katz, Roxana Knobel, Melania M R Amorim, Carla B Andreucci. Higher case fatality rate among obstetric patients with COVID-19 in the second year of pandemic in Brazil: do new genetic variants play a role? medRxiv 2021.05.06.21256651; doi: https://doi.org/10.1101/2021.05.06.21256651

Study 697 – 145 cases from USA

Treated in a public healthcare system, in Santa Clara County, California from April 15, 2020 to March 31, 2021 (click here or study). Citation: Song D, Prahl M, Gaw SL, et al. Passive and active immunity in infants born to mothers with SARS-CoV-2 infection during pregnancy: Prospective cohort study. Preprint. medRxiv. 2021;2021.05.01.21255871. Published 2021 May 3. doi:10.1101/2021.05.01.21255871 10 July update. Peer reviewed publication (click here or study). Citation: Song D, Prahl M, Gaw SL, et alPassive and active immunity in infants born to mothers with SARS-CoV-2 infection during pregnancy: prospective cohort studyBMJ Open 2021;11:e053036. doi: 10.1136/bmjopen-2021-053036

15 May update – studies 693 to 696 added

Study 696 – case report from USA

From Cedars‐Sinai Medical Center, Los Angeles, California (click here or study). Citation: Rushakoff JA, Polyak A, Caron J, et al. A case of a pregnant patient with COVID‐19 infection treated with emergency c‐section and extracorporeal membrane oxygenation. J Card Surg. 2021;1‐4. https://doi.org/10.1111/jocs.15623

Study 695 – two cases from Belgium

From author affiliations probably treated at Ghent University Hospital which has not previously reorted cases (click here or study). Citation: Libbrecht S, Van Cleemput J, Vandekerckhove L, Colman S, Padalko E, Verhasselt B, Van de Vijver K, Dendooven A, Dehaene I, Van Dorpe J. A rare but devastating cause of twin loss in a near-term pregnancy highlighting the features of severe SARS-CoV-2 placentitis. Histopathology. 2021 May 13. doi: 10.1111/his.14402. Epub ahead of print. PMID: 33982813.

Study 694 – 60 cases from Spain

This MedRxiv preprint describes lack of virus and presence of antibodies in breast milk (click here or study). Participants were recruited from 7 health centers from Valencia, Barcelona, Granada, and Zaragoza from April to December 2020 Citation: Christine Bauerl, Walter Randazzo, Gloria Sanchez, Marta Selma-Royo, Elia Garcia-Verdevio, Laura Martinez-Rodriguez, Anna Parra-Llorca, Carles Lerin, Victoria Fumado, Francesca Crovetto, Fatima Crispi, Francisco Jose Perez-Cano, Gerardo Rodriguez, Gema Ruiz-Redondo, Cristina Campoy, Cecilia Martinez-Costa, Maria Carmen Collado. SARS-CoV-2 RNA and antibody detection in human milk from a prospective multicenter study in Spain. medRxiv 2021.05.06.21256766; doi: https://doi.org/10.1101/2021.05.06.21256766

Study 693 – 1,062 cases from USA

Cases and controls collected from the Premier Healthcare Database, an all-payer data repository that captures 20% of U.S. hospitalizations (click here or study). Citation: Pineles BL, Goodman KE, Pineles L, O’Hara LM, Nadimpalli G, Magder LS, Baghdadi JD, Parchem JG, Harris AD. In-Hospital Mortality in a Cohort of Hospitalized Pregnant and Nonpregnant Patients With COVID-19. Ann Intern Med. 2021 May 11. doi: 10.7326/M21-0974. Epub ahead of print. PMID: 33971101.

4 May update – study 692 added

Study 692 – case report from the Netherlands

From Amsterdam Medical Centre (AMC) (click here or study). Citation: van Amesfoort JE, Werter DE, Painter RC, Hermans FJR. Severe metabolic ketoacidosis as a primary manifestation of SARS-CoV-2 infection in non-diabetic pregnancy. BMJ Case Rep. 2021 Apr 19;14(4):e241745. doi: 10.1136/bcr-2021-241745. PMID: 33875510.

3 May update – studies 690 and 691 added

Study 691 – 2,824 cases from Canada

The 3rd report from the CanCovid registry includes cases up to 31 December 2020 (click here or study). 1,880 cases reported in detail. Overlap with studies 510 and 690. Citation: Deborah Money. CANADIAN SURVEILLANCE OF COVID-19 IN PREGNANCY: EPIDEMIOLOGY, MATERNAL AND INFANT OUTCOMES Report #3: Released February 25, 2021. School of Population & Public Health, University of British Colombia

Study 690 – 1,940 cases from Canada

The 2nd report from the CanCovid registry includes cases up to 30 November 2020 (click here or study). 1,271 cases repoted in detail. Overlap with study 510. Citation: Deborah Money. CANADIAN SURVEILLANCE OF COVID-19 IN PREGNANCY: EPIDEMIOLOGY, MATERNAL AND INFANT OUTCOMES Report #2: Released January 15, 2021. School of Population & Public Health, University of British Colombia

1 May update – study 689 added

Study 689 – no hospital-acquired maternal infection in New York

Of 72 SARS-CoV-2 negative pregnant women admitted to New York Presbyterian Hospital/Columbia University Irving Medical Center between November 23, 2020 to March 3, 2021, none retested positive during their admission (click here or study). Citation: Zork NM, Markan A, Sheen J-J, AUBEY J, Saiman L, Goffman D, Serial Surveillance for SARS-CoV-2 in hospitalized antepartum women, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.04.222.

29 April update – study 688 added

Study 688 – 2,286 cases from Sweden

Collected from the National Swedish Pregnancy Register between March 11, 2020, and January 31, 2021 (click here or study). Baby outcomes compared with babies of all SARS-CoV-2 negative mothers, and with a matched control group. Probable overlap with studies 20, 88, 259b, 282, 298, 523, 588, 610 and 636. Citation: Norman M, Navér L, Söderling J, et al. Association of Maternal SARS-CoV-2 Infection in Pregnancy With Neonatal Outcomes. JAMA. Published online April 29, 2021. doi:10.1001/jama.2021.5775 [important]

28 April update – studies 686 & 687 added

Study 687 – case report from Japan

From Toho University Omori Medical Center, Tokyo, which has not previously reported cases (click here or study). Citation: Ito A, Hayata E, Nakata M, Shigeta T, Nakamura Y, Kishi K, Yoda H, Morita M. Rapid recovery achieved by intensive therapy after preterm cesarean section for worsening COVID-19-induced acute respiratory failure: A case report and literature review. Case Rep Womens Health. 2021 Apr;30:e00315. doi: 10.1016/j.crwh.2021.e00315. Epub 2021 Apr 18. PMID: 33898274; PMCID: PMC8053357.

Study 686 – 105 cases from Spain

Collected from hospitals participating in the GESNEO-COVID cohort between 15 March & 31 July 2020 (click here or study). The hospitals include General Universitario Gregorio Marañón; Hospital Universitario Infanta Sofía; Hospital La Fe; Hospital Materno Infantil de Badajoz; Complejo Hospitalario de Navarra; Hospital Universitario de Albacete; Hospital Universitario Infanta Elena; Hospital Parc Taulí ; Hospital Universitario HM Montepríncipe; Hospital General de Albace; Complejo Hospitalario de Navarra; Hospital Universitario Infanta Leonor; Hospital San Pedro de Alcántara; Complejo Hospitalario de Santiago, and Hospital 12 de Octubre. Only the last appears to have previously reported cases. However that hospital in Madrid has reported cases in studies 151, 165, 196, 205, 458, 470, 583 and 635. Citation: Carrasco I, Muñoz-Chapuli M, Vigil-Vázquez S, Aguilera-Alonso D, Hernández C, Sánchez-Sánchez C, Oliver C, Riaza M, Pareja M, Sanz O, Pérez-Seoane B, López J, Márquez E, Domínguez-Rodríguez S, Hernanz-Lobo A, De León-Luis JA, Sánchez-Luna M, Navarro ML. SARS-COV-2 infection in pregnant women and newborns in a Spanish cohort (GESNEO-COVID) during the first wave. BMC Pregnancy Childbirth. 2021 Apr 26;21(1):326. doi: 10.1186/s12884-021-03784-8. PMID: 33902483.

24 April update – studies 684 & 685 added, 610 updated, & numbering from 650 corrected

Study 685 – 240 cases from Mexico

Cared for at Instituto Nacional de Perinatologı´a Isidro Espinosa de los Reyes, (INPer), in Mexico City, between April 22 and May 25, 2020 (click here or study). This hospital has not previously reported cases although they likely overlap with other multicentre Mexican series. Citation: Cardona-Pérez JA, Villegas-Mota I, Helguera-Repetto AC, Acevedo-Gallegos S, Rodríguez-Bosch M, Aguinaga-Ríos M, Coronado-Zarco I, León-Juárez M, Aguilar-Ayala D, Valdespino-Vázquez MY, Moreno-Verduzco ER, Rivera MA, Valencia-Contreras C, Gómez-Sousa ML, Solis-Paredes M, Frías-Madrid B, Velasco-Téllez C, Rodriguez-Aldama JC, Avila-Sosa V, Galván-Contreras R, Figueroa-Damian R, Cortés-Bonilla M, Estrada-Gutierrez G, Espino-Y-Sosa S, Irles C. Prevalence, clinical features, and outcomes of SARS-CoV-2 infection in pregnant women with or without mild/moderate symptoms: Results from universal screening in a tertiary care center in Mexico City, Mexico. PLoS One. 2021 Apr 22;16(4):e0249584. doi: 10.1371/journal.pone.0249584. PMID: 33886590.

Study 684 – 250 cases from USA

255 neonates born to 250 mothers with Covid-19 between March 1 and July 31, 2020 (click here or study). Cared for at 11 hospitals in Massachusetts (Baystate; Beth Israel Deaconess; Beverly; Brigham & Women’s; Boston Medical Center; Cambridge Health Alliance; Massachusetts General; Newton-Wellesley; Tufts Children’s; UMass Memorial; Winchester). Probable overlap with studies 142, 231, 257, 262, 387, 488, 490, 519, 531, 550, 571, 577, 589, 591 and 606. Citation: Angelidou A, Sullivan K, Melvin PR, Shui JE, Goldfarb IT, Bartolome R, Chaudhary N, Vaidya R, Culic I, Singh R, Yanni D, Patrizi S, Hudak ML, Parker MG, Belfort MB. Association of Maternal Perinatal SARS-CoV-2 Infection With Neonatal Outcomes During the COVID-19 Pandemic in Massachusetts. JAMA Netw Open. 2021 Apr 1;4(4):e217523. doi: 10.1001/jamanetworkopen.2021.7523. PMID: 33890989.

22 April update – study 683 added

Study 683 –  706 cases & 1,424 controls from the Intergrowth-21 consortium

For each case, two control pregnancies were selected (click here or study). Collected from 43 institutions in 18 countries. Although some institutions had previously reported cases, the authors “excluded women/neonates from the final analysis if their data were already published in any comparative study with women without COVID-19 diagnosis”, and list the overlapping papers. These are studies 92, 102, 140, 144, 150, 161, 232, 246, 252 and 488. Citation: Villar J, Ariff S, Gunier RB, et al. Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study. JAMA Pediatr. Published online April 22, 2021. doi:10.1001/jamapediatrics.2021.1050 [important]

21 April update – study 682 added

Study 682 – case report from Germany

A pregnant woman with Covid-19 deteriorated post-partum and required ventilation and ECMO (click here or study). From author affiliations she was cared for at Vivantes Klinikum im Friedrichshain in Berlin, which has not previously reported cases. Citation: Maier JT, Zickler D, Metz M, Jebens A, Jarchau U, Fischer J, Kimmel V, Prueter E, Hellmeyer L. Peripartum Covid-19 Pneumonia with Severe ARDS – A Case Report. Z Geburtshilfe Neonatol. 2021 Apr;225(2):183-187. doi: 10.1055/a-1365-9262. Epub 2021 Apr 19. PMID: 33873231.

18 April update – studies 676 to 681 added

Study 681 – 72 cases from USA

Cared from at Boston Medical Center, Massachusetts (click here or study). Probable overlap with studies 292 and 490. Citation: Sabharwal V, Bartolome R, Hassan SA, Levesque BM, Camelo IY, Wachman EM, Figueira M, Yarrington CD, Cooper ER, Barnett ED, Parker MG. Mother-Infant Dyads with COVID-19 at an Urban, Safety-Net Hospital: Clinical Manifestations and Birth Outcomes. Am J Perinatol. 2021 Apr 14. doi: 10.1055/s-0041-1726429. Epub ahead of print. PMID: 33853145.

Study 680 – case report from USA

Cared for at University of California, Los Angeles (click here or study). Citation: Mok T, Contreras D, Chmait RH, Goldstein J, Pluym ID, Tabsh K, Aldrovandi G, Afshar Y. Complicated Monochorionic-Diamniotic Twins in a Pregnant Woman with COVID-19 in the Second Trimester. Am J Perinatol. 2021 Apr 14. doi: 10.1055/s-0041-1726428. Epub ahead of print. PMID: 33853148.

Study 679 – 56 cases from USA

Cared from at Kings County Hospital Center in New York, which has not previously reported cases (click here or study). Citation: Liu C, Andrusier M, Silver M, Applewhite L, Clare CA. Effect of SARS-CoV-2 Infection on Pregnancy Outcomes in an Inner-City Black Patient Population. J Community Health. 2021 Apr 15:1–7. doi: 10.1007/s10900-021-00988-z. Epub ahead of print. PMID: 33855649; PMCID: PMC8046575.

Study 678 – 34 patients from Turkey

Cared for at Kartal Training and Research Hospital, Istanbul, which has not previously reported cases (click here or study). Citation: Ozer KB, Sakin O, Koyuncu K, Cimenoglu B, Demirhan R. Comparison of Laboratory and Radiological Findings of Pregnant and Non-Pregnant Women with Covid-19. Rev Bras Ginecol Obstet. 2021 Mar;43(3):200-206. doi: 10.1055/s-0041-1726054. Epub 2021 Apr 15. PMID: 33860503.

Study 677 – 1,609 cases from USA

The Cerner COVID-19 De-Identified Data Cohort was used to compare pregnant women with Covid, with non-pregnant affected women aged 18-44 (click here or study). Although pregnant women were more likely to be hospitalised, they were no more likely to need invasive ventilation or die. They were cared for in 62 US hospitals with which Cerner had a data use agreement. Citation: Qeadan F, Mensah NA, Tingey B, Stanford JB. The risk of clinical complications and death among pregnant women with COVID-19 in the Cerner COVID-19 cohort: a retrospective analysis. BMC Pregnancy Childbirth. 2021 Apr 16;21(1):305. doi: 10.1186/s12884-021-03772-y. PMID: 33863292.

Study 676 – 18 cases from from Ireland

Cared for at Rotunda Hospital, Dublin (click here or study). Probable overlap with studies 284, 300 and 596. Citation: Alaya F, Worrall AP, O’toole F, Doyle J, Duffy RM, Geary MP. Health-related quality of life and quality of care in pregnant and postnatal women during the COVID-19 pandemic: A cohort study. Int J Gynaecol Obstet. 2021 Apr 16. doi: 10.1002/ijgo.13711. Epub ahead of print. PMID: 33864252.

16 April update – studies 674 and 675 added

Study 675 – 38 severe cases in UK

7/34 ECMO referrals of women aged 16-49 to the Royal Brompton Hospital in London in the first wave, were pregnant or post-partum, compared with 31/62 in the second wave (click here or study). This hospital has not previously reported cases, but there will be overlap with the various UKOSS and ICNARC reports. Citation: Suraj Kadiwar, Jonathan J Smith, Stephane Ledot, Mark Johnson, Paolo Bianchi, Natasha Singh, Claudia Montanaro, Michael Gatzoulis, Nishel Shah, Emem-Fong Ukor, Were pregnant women more affected by COVID-19 in the second wave of the pandemic?, The Lancet, 2021, ISSN 0140-6736, https://doi.org/10.1016/S0140-6736(21)00716-9. https://www.sciencedirect.com/science/article/pii/S0140673621007169)

Study 674 – 525 first wave cases from Italy

Collected by the Italian Obstetric Surveillance System (ITOSS) registry between 25 February and 31 July 2020 (click here or study). Likely overlap with study 536 and other Italian series. Citation: Donati, S.; Corsi, E.; Salvatore, M.A.; Maraschini, A.; Bonassisa, S.; Casucci, P.; Cataneo, I.; Cetin, I.; D’Aloja, P.; Dardanoni, G.; De Ambrosi, E.; Ferrazzi, E.; Fieni, S.; Franchi, M.P.; Gargantini, G.; Iurlaro, E.; Leo, L.; Liberati, M.; Livio, S.; Locci, M.; Marozio, L.; Martini, C.; Maso, G.; Mecacci, F.; Meloni, A.; Mignuoli, A.D.; Patanè, L.; Pellegrini, E.; Perotti, F.; Perrone, E.; Prefumo, F.; Ramenghi, L.; Rusciani, R.; Savasi, V.; Schettini, S.C.A.; Simeone, D.; Simeone, S.; Spinillo, A.; Steinkasserer, M.; Tateo, S.; Ternelli, G.; Tironi, R.; Trojano, V.; Vergani, P.; Zullino, S.; on behalf of the ItOSS COVID-19 Working Group. Childbirth Care among SARS-CoV-2 Positive Women in Italy. Int. J. Environ. Res. Public Health 2021, 18, 4244. https://doi.org/10.3390/ijerph18084244

15 April update – study 673 added

Study 673 – 75 cases from USA

The placentas were compared with those from 75 control pregnancies (click here or study). From author affiliations the patients had been cared for at Columbia University Irving Medical Center, New York. Citation: Debelenko L, Katsyv I, Chong AM, Peruyero L, Szabolcs M, Uhlemann AC. Trophoblast damage with acute and chronic intervillositis: disruption of the placental barrier by severe acute respiratory syndrome coronavirus 2. Hum Pathol. 2021 Mar;109:69-79. doi: 10.1016/j.humpath.2020.12.004. Epub 2020 Dec 13. PMID: 33321162; PMCID: PMC7733682.

14 April update – studies 671and 672 added

Study 672 – 50 cases from USA

From Loma Linda University Medical Center which has not previously reported cases (click here or study). Citation: Ruofan Yao, Courtney B Martin , Victoria S Haase , Beverly C Tse , Ms Melissa Nishino , Ciprian Gheorghe , Kevin Balli , Initial clinical characteristics of gravid SARS-CoV-2 positive patients and the risk of progression to severe COVID-19 disease, American Journal of Obstetrics & Gynecology MFM (2021), doi:https://doi.org/10.1016/j.ajogmf.2021.100365

Study 671 – 29 cases from Spain

From University Hospital La Paz, Madrid (click here or study). Probable overlap with study 196. Citation: Blasco Santana L, Miraval Wong E, Álvarez-Troncoso J, Sánchez García L, Bartha JL, Regojo-Zapata RM. Maternal and perinatal outcomes and placental pathologic examination of 29 SARS-CoV-2 infected patients in the third trimester of gestation. J Obstet Gynaecol Res. 2021 Apr 5. doi: 10.1111/jog.14784. Epub ahead of print. PMID: 33821521.

13 April update – studies 668 to 670 added

Study 670 – 110 cases from Iran

Collected between March and October 2020 from multiple hospitals in Tehran (click here or study). Five women died. Citation: Vizheh M, Muhidin S, Aghajani F, Maleki Z, Bagheri F, Hosamirudsari H, Aleyasin A, Tehranian A. Characteristics and outcomes of COVID-19 pneumonia in pregnancy compared with infected nonpregnant women. Int J Gynaecol Obstet. 2021 Apr 8. doi: 10.1002/ijgo.13697. Epub ahead of print. PMID: 33829492.

Study 669 – 1,454 cases from USA

From the Society for Obstetric Anesthesia and Perinatology (SOAP) COVID-19 Registry (click here or study). Collected from March 19-May 31, 2020 from 14 centres which, from author affiliations, probably include Brigham and Women’s Hospital, Boston; Weill Cornell, New York; Massachusetts General Hospital, Boston; University of California at San Francisco; Langone Health, New York, Stanford University School of Medicine, Emory School of Medicine, Atlanta, Icahn School of Medicine at Mount Sinai, New York; Mayo Clinic, Rochester; University of Maryland School of Medicine, Baltimore; Washington University School of Medicine, St. Louis; MGH-North Shore Medical Center, Danvers; Columbia University College of Physicians and Surgeons, New York. Citation: Katz D, Bateman BT, Kjaer K, Turner DP, Spence NZ, Habib AS, George RB, Toledano RD, Grant G, Madden HE, Butwick AJ, Lynde G, Minehart RD, Beilin Y, Houle TT, Sharpe EE, Kodali B, Bharadwaj S, Farber MK, Palanisamy A, Prabhu M, Gonzales NY, Landau R, Leffert L. The Society for Obstetric Anesthesia and Perinatology (SOAP) COVID-19 Registry: An analysis of outcomes among pregnant women delivering during the initial SARS-CoV-2 outbreak in the United States. Anesth Analg. 2021 Apr 8. doi: 10.1213/ANE.0000000000005592. Epub ahead of print. PMID: 33830956.

Study 668 – two cases from Chile

Two patients with severe Covid-19 were pregnant in this series of patients cared for in the Regional Hospital in Los Ríos (click here or study). Both were in the 2nd trimester. One was delivered by Caesarean at 28 weeks. This hospital has not previously reported cases. Citation: Olivares F, Muñoz D, Fica A, Delama I, Alvarez I, Navarrete M, Blackburn E, Garrido P, Wenger R, Grandjean J. Clinical features of 47 patients infected with COVID-19 admitted to a Regional Reference Center. Rev Med Chil. 2020 Nov;148(11):1577-1588. doi: 10.4067/S0034-98872020001101577. PMID: 33844763.

12 April update – studies 662 to 667 added

Study 667 – 5,479 cases from UK

This paper was prepared by the ISARIC4C Consortium, UK Obstetric Surveillance System (UKOSS) and COVID-19 Clinical Information Network (CO-CIN) for the UK Scientific Advisory Group for Emergencies (SAGE). It includes pregnant women with Covid from the whole of the UK. It is available as a pdf (click here or study) and as a set of powerpoint slides (click here or study). Citation: Marian Knight, Rema Ramakrishnan, Kathryn Bunch, Nicola Vousden, Jennifer J Kurinczuk, Sarah Dunn, Lisa Norman, Aisling Barry, Ewen Harrison, Annemarie Docherty, Calum Semple. Females in Hospital with SARS-CoV-2 infection, the association with pregnancy and pregnancy outcomes: A UKOSS/ISARIC/CO-CIN investigation. Report presented 25 March 2021. Published 9 April 2021 https://www.gov.uk/government/publications/ukossisaricco-cin-females-in-hospital-with-sars-cov-2-infection-the-association-with-pregnancy-and-pregnancy-outcomes-25-march-2021 Accessed 12 April 2021 [important]

Study 666 – 165 cases from Brazil

The patients were cared for in three different unnamed hospitals in São Paulo (click here or study). They may overlap with cases in studies 201, 213 and 426. Citation: Kiappe OP, Santos da Cruz NF, Rosa PAC, Arrais L, Bueno de Moraes NS. Ocular Assessments of a Series of Newborns Gestationally Exposed to Maternal COVID-19 Infection. JAMA Ophthalmol. Published online April 07, 2021. doi:10.1001/jamaophthalmol.2021.1088

Study 665 – 567 cases from Iran

Eight women died (click here or study). They were all cared for at Forghani Hospital in Qom. If this is the same as Nekouei-Hedayati-Forghani Hospital in the same city, some may have been reported in study 555. Neither hospital disambiguates on GRID.ac. Citation: Samadi, P., Alipour, Z., Ghaedrahmati, M. and Ahangari, R. (2021), The severity of COVID‐19 among pregnant women and the risk of adverse maternal outcomes. International Journal of Gynecology & Obstetrics. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13700

Study 664 – case report from Iran

Cared for at Firoozgar Hospital, Tehran (click here or study). The patient died, so may be included in study 345. Citation: Goudarzi, S, Firouzabadi, FD, Mahmoudzadeh, F, Aminimoghaddam, S. Pulmonary embolism in pregnancy with COVID‐19 infection: A case report. Clin Case Rep. 2021; 00: 1– 5. https://doi.org/10.1002/ccr3.3709

Study 663 – 68 cases from USA

This BioRxiv preprint reports a detailed study of placental immunology (click here or study). The hospitals caring for the patients are not reported, but from the last author affiliation might be Massachusetts General Hospital in Boston. Citation: Evan A Bordt, Lydia L Shook, Caroline Atyeo, Krista M Pullen, Rose M De Guzman, Marie-Charlotte Meinsohn, Maeva Chauvin, Stephanie Fischinger, Laura J. Yockey, Kaitlyn James, Rosiane Lima, Lael M Yonker, Alessio Fasano, Sara Brigida, Lisa M Bebell, Drucilla J Roberts, David Pépin, Jun R Huh, Staci D Bilbo, Jonathan Z Li, Anjali Kaimal, Danny Schust, Kathryn J Gray, Douglas Lauffenburger, Galit Alter, Andrea G Edlow. Sexually dimorphic placental responses to maternal SARS-CoV-2 infection bioRxiv 2021.03.29.437516; doi: https://doi.org/10.1101/2021.03.29.437516

Study 662 – 13 cases from China

Collected from centres outside Wuhan (click here or study). Some or all have probably been reported previously. Citation: Yangli Liu , Haihong Chen , Weiping Tan , Yukun Kuang , Kejing Tang , Yifeng Luo , Yubiao Guo , Clinical characteristics and outcome of SARS-CoV-2 infection during pregnancy, Journal of Infection (2021), doi: https://doi.org/10.1016/j.jinf.2021.03.030

11 April update – studies 658 to 661 added

Study 661 – 246 cases from Spain

Collected from the 45 hospitals of the Spanish Obstetric Emergency group (click here or study). Likely overlap with studies 264b, 548 and 589 as well as other Spanish report. Citation: Martinez-Perez O, Prats Rodriguez P, Muner Hernandez M, Encinas Pardilla MB, Perez Perez N, Vila Hernandez MR, Villalba Yarza A, Nieto Velasco O, Del Barrio Fernandez PG, Forcen Acebal L, Orizales Lago CM, Martinez Varea A, Muñoz Abellana B, Suarez Arana M, Fuentes Ricoy L, Martinez Diago C, Janeiro Freire MJ, Alférez Alvarez-Mallo M, Casanova Pedraz C, Alomar Mateu O, Lesmes Heredia C, Wizner de Alva JC, Bernardo Vega R, Macia Badia M, Alvarez Colomo C, Sanchez Muñoz A, Pratcorona Alicart L, Alonso Saiz R, Lopez Rodriguez M, Del Carmen Barbancho Lopez M, Meca Casbas MR, Vaquerizo Ruiz O, Moran Antolin E, Nuñez Valera MJ, Fernandez Fernandez C, Tubau Navarra A, Cano Garcia AM, Baena Luque C, Soldevilla Perez S, Gastaca Abasolo I, Adanez Garcia J, Teulon Gonzalez M, Puertas Prieto A, Ostos Serna R, Del Pilar Guadix Martin M, Catalina Coello M, Ferriols Perez E, Caño Aguilar A, De la Cruz Conty ML, Sainz Bueno JA; Spanish Obstetric Emergency Group. The association between SARS-CoV-2 infection and preterm delivery: a prospective study with a multivariable analysis. BMC Pregnancy Childbirth. 2021 Apr 1;21(1):273. doi: 10.1186/s12884-021-03742-4. PMID: 33794829; PMCID: PMC8016158.

Study 660 – 22 cases from USA

From Johns Hopkins Hospital, Baltimore, which has not previously reported cases (click here or study). Citation: Sherer ML, Lei J, Creisher P, Jang M, Reddy R, Voegtline K, Olson S, Littlefield K, Park HS, Ursin RL, Ganesan A, Boyer T, Elsayed N, Brown DM, Walch SN, Antar AAR, Manabe YC, Jones-Beatty K, Christopher Golden W, Satin AJ, Sheffield JS, Pekosz A, Klein SL, Burd I. Pregnancy alters IL-1β expression and anti-viral antibody responses during SARS-CoV-2 infection. Am J Obstet Gynecol. 2021 Mar 30:S0002-9378(21)00208-8. doi: 10.1016/j.ajog.2021.03.028. Epub ahead of print. PMID: 33798476; PMCID: PMC8008823.

Study 659 – case report from Italy

A woman with Covid-19 and twins cared for at the Institute for Maternal and Child Health “IRCCS Burlo Garofolo”, Trieste (click here or study). This hospital has not previously reported cases. Citation: Trombetta A, Comar M, Tommasini A, Canton M, Campisciano G, Zanotta N, Cason C, Maso G, Risso FM. SARS-CoV-2 Infection and Inflammatory Response in a Twin Pregnancy. Int J Environ Res Public Health. 2021 Mar 17;18(6):3075. doi: 10.3390/ijerph18063075. PMID: 33802696; PMCID: PMC8002573.

Study 658 – 30 cases from Italy

From Policlinico Umberto I Hospital, Sapienza University of Rome (click here or study). This hospital appears to have only reported one previous case in study 448. Citation: Porpora MG, Merlino L, Masciullo L, D’Alisa R, Brandolino G, Galli C, De Luca C, Pecorini F, Fonsi GB, Mingoli A, Franchi C, Oliva A, Manganaro L, Mastroianni CM, Piccioni MG. Does Lung Ultrasound Have a Role in the Clinical Management of Pregnant Women with SARS COV2 Infection? Int J Environ Res Public Health. 2021 Mar 9;18(5):2762. doi: 10.3390/ijerph18052762. PMID: 33803223; PMCID: PMC7967479.

3 April update – studies 654 to 657 added

Study 657 – case report from Iran

Neurosurgical complications from Covid-19 in pregnancy are described (click here or Saberi case rep). From author affiliations the patient was cared for, and delivered by Caesarean, in Imam Khomeini hospital, Tehran, which has not previously reported cases. Citation: Saberi H, et al, Acute presentation of third ventricular cavernous malformation following COVID-19 infection in a pregnant woman: A case report, Neurochirurgie, https://doi.org/10.1016/j.neuchi.2021.03.010

Study 656 – case report from Japan

From author affiliations the patient who required ventilation, but recovered was probably cared for at University of the Ryukyus Hospital, Okinawa, which has not previously reported cases (click here or Chinen case rep). Citation: Y. Chinen, Y. Kinjyo, K. Mekaru, et al., Critical respiratory failure in pregnancy complicated with COVID-19: A case report, Case Reports in Women’s Health (2018), https://doi.org/10.1016/j.crwh.2021.e00309

Study 655 – 45 cases from Canada

From author affiliations the women were cared for at McGill University Health Centre, and Jewish General Hospital Montreal (click here or Trahan Montreal). Citation: Marie-Julie Trahan, Isabelle Malhame, Patrick O’Farrell, Cristina Mitric, Jade Desilets, Marie-Pier Bastrash, Amira El-Messidi, Haim A. Abenhaim, Obstetrical and Newborn Outcomes among Patients with SARS-CoV-2 during Pregnancy, Journal of Obstetrics and Gynaecology Canada (2021),
doi: https://doi.org/10.1016/j.jogc.2021.03.012

Study 654 – 458 cases from Chile

From Hospital San Jose, Santiago, 8 April – 30 August 2020 (click here or Haye Chile). One mother died. A different hospital Study 486, which has not previously reported cases. Citation: Maria Teresa Haye, Giorgia Cartes, Jorge Gutiérrez, Paz Ahumada, Bernardo Krause, Mario Merialdi & Rogelio Gonzalez (2021): Maternal and perinatal outcomes in pregnant women with confirmed severe and mild COVID-19 at one large maternity hospital in Chile, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2021.1902498

30 March update – studies 652 and 653 added

Study 653 – 64 cases from Egypt

This MedRxiv preprint includes 64 pregnant women, of whom three died (click here or paper). Citation: Noha Asem, Mohamed Hassany, Khaled Taema, Hossam Masoud, Gehan Elassal, Ehab Kamal, Wagdy Amin, Akram Abdelbary, Amin Abdel Baki, Samy Zaky, Ahmad Abdalmohsen, Hamdy Ibrahim, Mohamed Elnady, Ahmed Mohamed, Ehab Atteia, Hala Zaid. Demographic and clinical features associated with in-hospital mortality in Egyptian COVID-19 patients: A retrospective cohort study. medRxiv 2021.03.22.21253577; doi: https://doi.org/10.1101/2021.03.22.21253577

Study 652 – 708 cases from Norway

This MedRxiv preprint includes 708 pregnant women with a positive test from the Norwegian National Population Registry between March 1st, 2020 and February 28th, 2021 (click here or paper). Citation: Maria C. Magnus, Laura Oakley, Håkon K. Gjessing, Olof Stephansson, Hilde M. Engjom, Ferenc Macsali, Petur B. Juliusson, Anne-Marie Nybo Andersen, Siri E. Håberg. Pregnancy and risk of COVID-19. medRxiv 2021.03.22.21254090; doi: https://doi.org/10.1101/2021.03.22.21254090

21 March update – study 651 added

Study 651 – 2 cases in two US fertility clinics

Both asymptomatic (click here or PIIS0002937821001599). Six other women, out of 339 showed evidence of past infection. The clinics were Utah Fertility Center, Utah, and Boston IVF, Massachusetts. Citation: FOULK R, SAKKAS D, KAYALI R, VALBUENA D, SIMON C, CUZZI J, SARSCoV-2 immunity, infective and naïve incidence in fertility clinics after lockdown, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.03.008.&nbsp;

20 March update – studies 648 to 650 added

Study 650 – 132 cases from India

Cared for between 15th May and 15th November 2020, at Tata Main Hospital, Jamshedpur, which has not previously reported cases (click here or cureus-0013-00000013184). Citation: Singh V, Choudhary A, Datta MR, Ray A. Maternal and Neonatal Outcomes of COVID-19 in Pregnancy: A Single-Centre Observational Study. Cureus. 2021 Feb 6;13(2):e13184. doi: 10.7759/cureus.13184. PMID: 33717728; PMCID: PMC7943051.

Study 649 – Case report from USA

The authors are affiliated with the Medical College of Wisconsin, Milwaukee, Wisconsin (click here or e240385.full). The clinical details differ from the case in study 563. Citation: Roddy JT, Collier WS, Kurman JS. Prone positioning for severe ARDS in a postpartum COVID-19 patient following caesarean section. BMJ Case Rep. 2021 Mar 16;14(3):e240385. doi: 10.1136/bcr-2020-240385. PMID: 33727296.

Study 648 – one case from UK

From 7 May to 6 June 2020, 1/465 asymptomatic pregnant women from The Rosie Hospital in Cambridge tested positive (click here or s12884-021-03653-4). The Rosie has not previously reported cases. Citation: Xu R, Pauley TA, Missfelder-Lobos H, Haddon RJ, Gupta RK, Chong HP. Samba II PCR testing for COVID-19 in pregnant women: a retrospective cohort study and literature review. BMC Pregnancy Childbirth. 2021 Mar 17;21(1):212. doi: 10.1186/s12884-021-03653-4. PMID: 33731037.

16 March – study 647 added

Study 647 – 36 cases from UK

This MedRxiv preprint from ICNARC, QResearch, and the COVID-19 testing (PHE) database, reports 36 pregnant or recently pregnant women in critical care with Covid-19, between 1 November 2020 and 27 January 2021, of whom 25 were infected with the variant of concern (VOC) B.1.1.7 (click here or 2021.03.11.21253364v1.full). Citation: Martina Patone, Karen Thomas, Rob Hatch, Pui San Tan, Carol Coupland, Weiqi Liao, Paul Mouncey, David Harrison, Kathryn Rowan, Peter Horby, Peter Watkinson, Julia Hippisley-Cox Analysis of severe outcomes associated with the SARS-CoV-2 Variant of Concern 202012/01 in England using ICNARC Case Mix Programme and QResearch databases. medRxiv 2021.03.11.21253364; doi: https://doi.org/10.1101/2021.03.11.21253364

13 March update – study 646 added. Full text added to study 576

Study 646 – Case report from UK

Cared for at East and North Hertfordshire NHS Trust, Stevenage, in April 2020 (click here or e238055.full). Likely included in studies 533, 539 and perhaps others. Citation: Reindorf M, Newman J, Ingle T. BMJ Case Rep 2021;14:e238055. doi:10.1136/bcr-2020-238055

8 March update – studies 642 to 645 added. Study 541, English version added

Study 645 – case report from Brazil

From author affiliations she was probably cared for at the Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, which has not previously reported cases (click here or fmed-08-624166). Citation JAK B, Zanirati G, Rodrigues FVF, et al. Case Report: Placental Maternal Vascular Malperfusion Affecting Late Fetal Development and Multiorgan Infection Caused by SARS-CoV-2 in Patient With PAI-1 4G/5G Polymorphism. Front Med (Lausanne). 2021;8:624166. Published 2021 Feb 17. doi:10.3389/fmed.2021.624166

Study 644 – 17 serologically positive cases from Italy

It is not clear which Turin hospital cared for these patients (click here or diagnostics-11-00398). They may therefore overlap with those in studies 79, 167, 195, 247 and 615. Citation: Cosma S, Carosso AR, Borella F, Cusato J, Bovetti M, Bevilacqua F, Carosso M, Gervasoni F, Sciarrone A, Marozio L, Revelli A, Rolfo A, Filippini C, Ghisetti V, Di Perri G, Benedetto C. Prenatal Biochemical and Ultrasound Markers in COVID-19 Pregnant Patients: A Prospective Case-Control Study. Diagnostics (Basel). 2021 Feb 26;11(3):398. doi: 10.3390/diagnostics11030398. PMID: 33652805.

Study 643 – case report from USA

Cared for at McGovern Medical School, University of Texas Health Science Center, Houston (click here or cureus-0013-00000012990). May be included in study 267b. Citation: Moses ML, Kazzi NG, Lee L. Severe Thrombocytopenia in a Pregnant Patient with Asymptomatic COVID-19 Infection: A Case Report. Cureus. 2021 Jan 29;13(1):e12990. doi: 10.7759/cureus.12990. PMID: 33654642; PMCID: PMC7916745.

Study 642 – 142 cases from USA

Cared for at New York Presbyterian, Brooklyn Methodist Hospital between March and August 2020 (click here or Zhang JMFM Feb 28 14767058.2021). Probably included in a number of New York series. Citation: Peilin Zhang, Taryn Heyman, Marisa Greechan, Beata Dygulska, Farah Al Sayyed, Pramod Narula & Sanford Lederman (2021) Maternal, neonatal and placental characteristics of SARS-CoV-2 positive mothers, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2021.1892637

7 March update – Study 641 added

Study 641 – 50 cases from Italy

From Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, so likely included in the various series from there and Lombardy  (click here or jog.14729). Citation: D’Ambrosi F, Iurlaro E, Tassis B, Di Maso M, Erra R, Cetera GE, Cesano N, Di Martino D, Ossola MW, Ferrazzi EM. Sociodemographic characteristics of pregnant women tested positive for COVID-19 admitted to a referral center in Northern Italy during lockdown period. J Obstet Gynaecol Res. 2021 Mar 1. doi: 10.1111/jog.14729. Epub ahead of print. PMID: 33650278.

6 March update – study 640 added

Study 640 – 54 cases from Turkey

54 pregnant women with Covid-19 cared for in Ankara City Hospital between August 1 and October 1, 2020 (click here or [full text not yet available]). Likely overlap with studies 203, 223, 399, 512, 569 and 604. Citation: Ayhan SG, Tanacan A, Atalay A, Sinaci S, Tokalioglu EO, Sahin D, Tekin OM. Assessment of fetal Doppler parameters in pregnant women with COVID-19 infection: a prospective case-control study. J Perinat Med. 2021 Mar 3. doi: 10.1515/jpm-2020-0512. Epub ahead of print. PMID: 33660492.

4 March update – studies 638 and 639 added

Study 639 – 5,963 cases from USA

This MedRxiv preprint includes pregnant women testing positive for SARS-CoV-2 identified though the Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET) between March 29, and January 8, 2021 (click here or 2021.02.27.21252169v1.full). They likely overlap with those in study 338Citation: Romeo R. Galang, Suzanne M. Newton, Kate R. Woodworth, Isabel Griffin, Titilope Oduyebo, Christina L. Sancken, Emily O’Malley Olsen, Kathy Aveni, Heather Wingate, Hanna Shephard, Chris Fussman, Zahra S. Alaali, Samantha Siebman, Umme-Aiman Halai, Camille Delgado Lopez, Jerusha Barton, Mamie Lush, Paul H. Patrick, Levi Schlosser, Ayomide Sokale, Ifrah Chaudhary, Bethany Reynolds, Similoluwa Sowunmi, Nicole Gaarenstroom, Jennifer S. Read, Sarah Chicchelly, Leah de Wilde, Eduardo Azziz-Baumgartner, Aron J. Hall, Van T. Tong, Sascha Ellington, Suzanne M. Gilboa Risk factors for illness severity among pregnant women with confirmed SARS-CoV-2 infection – Surveillance for Emerging Threats to Mothers and Babies Network, 20 state, local, and territorial health departments, March 29, 2020 -January 8, 2021 CDC COVID-19 Response Pregnancy and Infant Linked Outcomes Team medRxiv 2021.02.27.21252169; doi: https://doi.org/10.1101/2021.02.27.21252169

Study 638 – 83 cases from USA

From Barnes-Jewish Hospital in St. Louis, Missouri between June 1, and November 30, 2020 (click here or Rosenbloom AJOG PIIS0002937821001502). They likely overlap with cases in studies 69, 259, 290 and possibly 579. Citation: Rosenbloom JI, Raghuraman N, Carter EB, Kelly JC, COVID-19 Infection and Hypertensive Disorders of Pregnancy, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.03.001.

2 March update – studies 636 and 637 added

Study 637 – case report from USA

The hospital is not named, but the authors are affiliated with the Whole Family Health Center, Vero Beach, Florida, which has not previously reported cases (click here or 1-s2.0-S2214911221000059-main). Citation: Poisson TM, Pierone G Jr. Placental pathology and fetal demise at 35 weeks of gestation in a woman with SARS-CoV-2 infection: A case report. Case Rep Womens Health. 2021 Apr;30:e00289. doi: 10.1016/j.crwh.2021.e00289. Epub 2021 Jan 28. PMID: 33527073; PMCID: PMC7840395.

Study 636 – case report from Sweden

Probably included in study 610 (click here or Zaigham case BJOG in press). Although cared for at either Lund or Malmo hospitals clinical details differ from cases in studies 259b and 588. Citation: Zaigham M, Holmberg A, Karlberg ML, Lindsjö OK, Jokubkiene L, Sandblom J, Strand AS, Andersson O, Hansson SR, Nord DG, Tannenberg P. Intrauterine vertical SARS-CoV-2 infection: a case confirming transplacental transmission followed by divergence of the viral genome. BJOG. 2021 Feb 27. doi: 10.1111/1471-0528.16682. Epub ahead of print. PMID: 33638908.

28 February update – study 635 added

Study 635 – 12 cases from Spain 

From author affiliations they were cared for at Vall d’Hebron Hospital, Barcelona, and Hospital Universitario “12 de Octubre”, Madrid, between 1 March and 31 April 2020 (click here or ). They probably overlap with cases in studies 151, 165, 185, 205, 413, 417, 458, 470 and 583. Citation: Jiménez-Lozano I, Caro-Teller JM, Fernández-Hidalgo N, Miarons M, Frick MA, Batllori Badia E, Serrano B, Parramon-Teixidó CJ, Camba-Longueira F, Moral-Pumarega MT, San Juan-Garrido R, Cabañas Poy MJ, Suy A, Gorgas Torner MQ. Safety of tocilizumab in COVID-19 pregnant women and their newborn: A retrospective study. J Clin Pharm Ther. 2021 Feb 26. doi: 10.1111/jcpt.13394. Epub ahead of print. PMID: 33638257.

27 February update – studies 628 to 634 added

Study 634 – 13 cases from Spain

These 13 pregnant women with Covid-19 were cared for at five public hospitals in Valencia (Hospital Universitario de La Ribera, Hospital Lluis Alcanyis, Hospital de Ontinyent, Hospital General de Valencia and Hospital Universitari i Politècnic La Fe), none of which have previously reported cases (click here or 1-s2.0-S1130862121000334-main). They may of course be included in Spanish or international registries. Spanish, with English abstract. Citation: R. Vila-Candel, D. Mena-Tudela, A. Gómez-Seguí et al., Manejo del parto, el puerperio y la lactancia en mujeres positivas para SARS-CoV-2. Estudio multicéntrico en la Comunidad Valenciana, Enfermería Clínica, https://doi.org/10.1016/j.enfcli.2021.01.006

Study 633 – 58 cases from USA

These pregnant women with Covid-19  were cared for at the University of Iowa Hospitals and Clinics, which have not previously reported cases (click here or Steffen Iowa AJP s-0041-1723938). However the woman reported in study 537 is probably also in this series. Citation: Steffen HA, Swartz SR, Jackson JB, Kenne KA, Ten Eyck PP, Merryman AS, Castaneda CN, Marsden K, Maxwell T, Merrill AE, Krasowski MD, Rysavy MB. SARS-CoV-2 Infection during Pregnancy in a Rural Midwest All-delivery Cohort and Associated Maternal and Neonatal Outcomes. Am J Perinatol. 2021 Feb 21. doi: 10.1055/s-0041-1723938. Epub ahead of print. PMID: 33611783.

Study 632 – 583 cases from Mexico

This report (click here or excli2021-3413) of 395,343 patients with COVID-19 in 688 medical units in Mexico City between February 24 and September 14, 2020, includes 583 pregnant women, of whom 10 died. See supplementary tables 3, 8 and 15 for pregnancy data excli2021-3413_supplementary_information. They likely overlap with cases reported in studies 271, 340, 425, 475, 513 and 518. Citation: Mancilla-Galindo, J., García-Méndez, J. Óscar, Marquéz-Sánchez, J., Reyes-Casarrubias, R. E. ., Aguirre-Aguilar, E., Rocha-González, H. I., & Kammar-García, A. (2021). All-cause mortality among patients treated with repurposed antivirals and antibiotics for COVID-19 in Mexico City: A real-world observational study. EXCLI Journal, 20, 199-222. https://doi.org/10.17179/excli2021-3413

Study 631 – case report from China

Cared for in March 2020 in Peking (Beijing) University Third Hospital grid.411642.4 (click here or JCTH-9-133). This hospital has not previously reported cases and does not seem to be included in the various non-Wuhan China series. Citation: Li QY, An ZY, Li C, et al. Chronic Active Hepatitis B with COVID-19 in Pregnancy: A Case Report. J Clin Transl Hepatol. 2021;9(1):133-135. doi:10.14218/JCTH.2020.00085

Study 630 – 81 cases from Turkey

55/81 with chest X ray or CT are reported (click here or JTGGA-0-0-En). From author affiliations they were cared for in Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, and Marmara University Faculty of Medicine, both in Istanbul. The cases may therefore overlap with those in studies 146, 210, 244 and 286. Citation: Kuzan TY, Murzoğlu Altıntoprak K, Çiftçi HÖ, Kuzan BN, Yassa M, Tuğ N, Çimşit NÇ. Clinical and radiologic characteristics of symptomatic pregnant women with COVID-19 pneumonia. J Turk Ger Gynecol Assoc. 2021 Feb 26. doi: 10.4274/jtgga.galenos.2021.2020.0215. Epub ahead of print. PMID: 33631874.

Study 629 – 45 cases from USA

Of these 45 cases from Einstein Medical Center Philadelphia, three re-tested positive more than 90 days later (click here or 1-s2.0-S2589933321000264-main). Probably includes the case reported in study 320. Citation: Emily Dubelbeiss, Michael Silverberg, Chase White, David Jaspan, Christopher Haines, Jay Goldberg, Repeat positive SARS-CoV-2 (COVID-19) testing e 90 days apart in pregnant women., American Journal of Obstetrics & Gynecology MFM (2021), doi: https://doi.org/10.1016/j.ajogmf.2021.100331

Study 628 – 887 cases from WAPM

These cases collected from 76 centers in 25 countries, and diagnosed between 04 April & 28 October 2020 overlap with those in studies 278 and 415 and other studies (click here or 1-s2.0-S2589933321000240-main). The centres can be inferred from author affilations, but case numbers by centre are not reported.  Citation: Francesco D’Antonio, Cihat Sen, Daniele DI Mascio, et al. Maternal and perinatal outcomes in high vs low risk-pregnancies affected by SARS-COV-2 infection (Phase-2): The WAPM (World Association of Perinatal Medicine) working group on COVID-19, American Journal of Obstetrics & Gynecology MFM (2021), doi: https://doi.org/10.1016/j.ajogmf.2021.100329

23 February update – study 539 (UK PanCovid & US AAP SONPM registries) updated

21 February update – studies 619 to 627 added

Study 627 – 49 cases from Italy

From Università di Roma Tor Vergata, from September to November 2020 (click here or aogs.14130). Citation: Rizzo, G., Mappa, I., Maqina, P., Bitsadze, V., Khizroeva, J., Makatsarya, A. and D’Antonio, F. (2021), Effect of SARS‐CoV‐2 infection during the second half of pregnancy on fetal growth and hemodynamics: a prospective study. Acta Obstetricia et Gynecologica Scandinavica. Accepted Author Manuscript. https://doi.org/10.1111/aogs.14130 [case series & controls, 2nd wave]

Study 626 – 247 cases from Germany

Collected from 65 hospitals participating in the CRONOS registry between 3 April and 1 October 2020 (click here or CRONOS). 14 women were treated in ITU. No maternal deaths were reported, although 32 women have not yet recovered. Of 189 completed pregnancies, there were 4 terminations, 2 stillbirths and 183 livebirths. Four neonates were infected but all recovered. Although German cases were included in studies 127 and 278 this is the first substantive rport from Germany. Citation: Pecks U, Kuschel B, Mense L, Oppelt P, Rüdiger M, on behalf of the CRONOS network: Pregnancy and SARS-CoV-2 infection in Germany—the CRONOS registry. Dtsch Arztebl Int 2020; 117: 841–2. DOI: 10.3238/arztebl.2020.0841 [important]

Study 625 – case report from USA

From MedStar Washington Hospital Center, Washington DC (click here or 10-1055-s-0040-1721672). The clinical details differ from those in study 21 from the same hospital. Citation: Mokhtari NB, Drassinower D, Orr LA, Cobb NK, Mims OL Jr, Landy HJ. Expectant Management of Severe COVID-19 Pneumonia in Late Preterm Pregnancy and Subsequent Cholecystitis: Lessons Learned. AJP Rep. 2021;11(1):e29-e33. doi:10.1055/s-0040-1721672

Study 624 – 4 cases from India

Of four pregnant women with Covid-19 in pregnancy treated in Bundelkhand Medical College Hospital, Sagar City, one died (click here or jog.14696). This hospital has not previously reported cases. Citation: Rawat, S.K., Saad, T., Jindal, A. and Vyas, A.K. (2021), Coronavirus disease 2019 in pregnancy: Case report on maternal death in Sagar City of Central India. J. Obstet. Gynaecol. Res.. https://doi.org/10.1111/jog.14696

Study 623 – Case report from Japan

From Kyoto Prefectural University of Medicine, which as not previously reported cases (click here or jog.14701). Citation: Waratani, M., Ito, F., Tanaka, Y., Mabuchi, A., Mori, T. and Kitawaki, J. (2021), Severe coronavirus disease pneumonia in a pregnant woman at 25 weeks’ gestation: A case report. J. Obstet. Gynaecol. Res.. https://doi.org/10.1111/jog.14701

Study 622 – Case report from Iran

From Arash Hospital, Tehran University of Medical Sciences, Tehran (click here or Rabiei JMCR). The clinical features and hospital suggest these are the same triplets as previously reported in studies 250 and 409. Citation: Rabiei, M., Soori, T., Abiri, A. et al. Maternal and fetal effects of COVID-19 virus on a complicated triplet pregnancy: a case report. J Med Case Reports 15, 87 (2021). https://doi.org/10.1186/s13256-020-02643-y

Study 621 –  Case report from Turkey

From Konya Education and Research Hospital, Konya, which has not previously reported cases (click here or Gunduz). Citation: GUNDUZ, Zahide Betül. Venous sinus thrombosis during COVID-19 infection in pregnancy: a case report. Sao Paulo Med. J. [online]. In press. [cited 2021-02-21], pp.-. Available from: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802021005005202&lng=en&nrm=iso&gt;. Epub Feb 15, 2021. ISSN 1806-9460. https://doi.org/10.1590/1516-3180.2020.0659.r1.08122020.

Study 620 – 17 cases from Brazil

Of 360 women aged <20 with Covid-19 in Pernambuco, from March 12 to June 19, 2020, 17 were pregnant or in the puerperium (click here or [14761645 – The American Journal of Tropical Medicine and Hygiene] Clinical Characteristics and Mortality Profile of COVID-19 Patients Aged less than 20 years Old in Pernambuco – Brazil). None died. Citation: Sena GR, Lima TPF, Vidal SA, Duarte MDCMB, Bezerra PGM, Fonseca Lima EJ, Braga C, Andrade LB, Lins MM, Torres LC, Lima JTO, Mello MJG. Clinical Characteristics and Mortality Profile of COVID-19 Patients Aged less than 20 years Old in Pernambuco – Brazil. Am J Trop Med Hyg. 2021 Feb 18: tpmd201368. doi: 10.4269/ajtmh.20-1368. Epub ahead of print. PMID: 33606669.

Study 619 – 240 cases from USA

From Washington state (click here or Lokken AJOG Feb 21). These appear to be the same cases as in study 573. Citation: LOKKEN EM, TAYLOR GG, HUEBNER EM, VANDERHOEVEN J, HENDRICKSON S, COLER B, SHENG JS, WALKER CL, MCCARTNEY SA, KRETZER NM, RESNICK R, KACHIKIS A, BARNHART N, SCHULTE V, BERGAM B, K K, ALBRIGHT C, LARIOS V, KELLEY L, LARIOS V, EMHOFF S, RAH J, RETZLAFF K, THOMAS C, PAEK BW, HSU RJ, ERICKSON A, CHANG A, MITCHELL T, HWANG JK, GOURLEY R, ERICKSON S, DELANEY S, KLINE CR, ARCHABALD K, BLAIN M, LACOURSE SM, ADAMS WALDORF KM, Higher SARS-CoV-2 Infection Rate in Pregnant Patients, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.02.011.

15 February update – studies 615 to 618 added

Study 618 – 350 cases from India

From Government Medical College Kannur, Pariyaram, in Kerala, which has not previously reported cases (click here or 13224_2021_Article_1436). Two mothers were admitted to ITU, one of whom was ventilated. Of 221 babies 32 tested positive. Citation: Ajith S, Reshmi VP, Nambiar S, Naser A, Athulya B. Prevalence and Risk Factors of Neonatal Covid-19 Infection: A Single-Centre Observational Study. J Obstet Gynaecol India. 2021 Feb 4:1-4. doi: 10.1007/s13224-021-01436-7. Epub ahead of print. PMID: 33564217; PMCID: PMC7861010. [breastfeeding, rooming in]

Study 617 – Case report from Indonesia

A woman with Covid-19 delivered twins at 32 weeks by Caesarean (click here or main (3)). One twin had an ileal perforation. Mother and babies were cared for at Dr. Soetomo General Hospital, Surabaya, which has not previously reported cases. Citation: Harahap A, Harianto A, Etika R, Utomo MT, Angelika D, Handayani KD, Arif Sampurna MT. Spontaneous Ileum Perforation in a premature twin with Coronavirus-19 positive mother. J Pediatr Surg Case Rep. 2021 Feb 4:101807. doi: 10.1016/j.epsc.2021.101807. Epub ahead of print. PMID: 33564621; PMCID: PMC7860962.

Study 616 – 91 cases from USA

From the University of Texas Medical Branch Galveston, Texas which has not previously reported cases (click here or s-0041-1723761). Citation: Berry M, Wang A, Clark SM, Harirah HM, Jain S, Olson GL, Pacheco LD, Saade GR, Saad AF. Clinical Stratification of Pregnant COVID-19 Patients based on Severity: A Single Academic Center Experience. Am J Perinatol. 2021 Feb 6. doi: 10.1055/s-0041-1723761. Epub ahead of print. PMID: 33548937. [case series]

Study 615 – 17 patients with antibodies from Italy

These pregnant women were probably cared for at S. Anna Hospital, Turin (click here or 1-s2.0-S0165037821000152-main). They may therefore overlap with studies 79, 167, 195 and 247. Citation: Stefano Cosma, Andrea Roberto Carosso, Silvia Corcione, Jessica Cusato, Fulvio Borella, Miriam Antonucci, Luca Marozio, Alberto Revelli, Mario Preti, Valeria Ghisetti, Giovanni Di Perri, Chiara Benedetto. Longitudinal analysis of antibody response following SARS-CoV-2 infection in pregnancy: From the first trimester to delivery. Journal of Reproductive Immunology, Volume 144, 2021, 103285, ISSN 0165-0378, https://doi.org/10.1016/j.jri.2021.103285. (https://www.sciencedirect.com/science/article/pii/S0165037821000152) [neonatal antibodies]

13 February update – studies 611 to 614 added

Study 614 – serum screening in Jamaica

From University Hospital of the West Indies, in Kingston, during September-November 2020 (click here or Chisolm preprint). Citation: Te’Anne Chisolm, Jerome P Walker, Ynolde Leys, Tiffany R Butterfield, Candice Medley, Tamara K Thompson, Glendee Reynolds-Campbell, Willem H Mulder, Michelle Campbell Mitchell, Joshua J Anzinger. SARS-CoV-2 Seroprevalence Among Antenatal Clinic Attendees in Kingston, Jamaica, September-November 2020. medRxiv 2021.02.08.21251367; doi: https://doi.org/10.1101/2021.02.08.21251367 [2nd wave]

Study 613 – serum screening in Kenya

From Kenyatta National Hospital in Nairobi between 30th July and 25th August (click here or 2021.02.05.21250735v1.full). Citation: R. Lucinde, D. Mugo, C. Bottomley, R Aziza, J. Gitonga, H. Karanja, J. Nyagwange, J. Tuju, P. Wanjiku, E. Nzomo, E. Kamuri, K. Thuranira, S. Agunda, G. Nyutu, A. Etyang, I. M. O. Adetifa, E. Kagucia, S. Uyoga, M. Otiende, E. Otieno, L. Ndwiga, C. N. Agoti, R. Aman, M. Mwangangi, P. Amoth, K. Kasera, A. Nyaguara, W. Ng’ang’a, L. B. Ochola, E. Barasa, P. Bejon, B. Tsofa, L. I. Ochola-Oyier, G. M. Warimwe, A. Agweyu, J. A. G. Scott, K. E. Gallagher. Sero-surveillance for IgG to SARS-CoV-2 at antenatal care clinics in two Kenyan referral hospitals. medRxiv 2021.02.05.21250735; doi: https://doi.org/10.1101/2021.02.05.21250735

Study 612 – 14 cases from Spain

Interim report of a planned follow-up study (click here or MOACC-19 study 2020.08.20.20178657v2.full). Citation: Javier Llorca, Carolina Lechosa-Muñiz, Pilar Gortázar, María Fernández-Ortiz, Yolanda Jubete, María J. Cabero, the MOACC-19 group, Jéssica Alonso-Molero, Bárbara Arozamena, Laura Conde-Gil, Elsa Cornejo del Río, Rocío Cuesta-González, Trinidad Dierssen-Sotos, Pelayo Frank de Zulueta, Inés Gómez-Acebo, Coral Llano-Ruiz, Lorena Lasarte-Oria, Sonia López-Gómez, Sonia Mateo-Sota, Victoria Orallo, Rosa Pardo, Daniel Pérez González, María Sáez de Adana Herrero. Cohort profile: COVID-19 in a cohort of pregnant women and their descendants, the MOACC-19 study. medRxiv 2020.08.20.20178657; doi: https://doi.org/10.1101/2020.08.20.20178657

Study 611 – ISARIC again

Among 240,149 patients admitted to hospital with covid-19 in the UK, 1,502/17,850 women of childbearing age, were reported as being pregnant (click here or 2020.07.17.20155218v6.full). Citation: Martina Escher, Matthew Hall, J Kenneth Baillie, Joaquin Baruch, Lucille Blumberg, Gail Carson, Barbara Wanjiru Citarella, Emmanuelle Dankwa, Annemarie B Docherty, Murray Dryden, Christl Donnelly, Jake Dunning, Christophe Fraser, Hayley Hardwick, Ewen M Harrison, Karl Holden, Waasila Jassat, Christiana Kartsonaki, Kalynn Kennon, James Lee, Kenneth McLean, Caroline Mudara, Peter JM Openshaw, Daniel R Plotkin, Mark Pritchard, Amanda Rojek, Clark D Russell, Malcolm Gracie Semple, Louise Sigfrid, Susan Smith, Jia Wei, Peter Horby, Piero L Olliaro, Laura Merson. ISARIC COVID-19 Clinical Data Report: 10 February 2021 medRxiv 2020.07.17.20155218; doi: https://doi.org/10.1101/2020.07.17.20155218 [2nd wave]

12 February update – study 610 added

Study 610 – 214 cases from Scandinavia

These cases were collected by the Nordic Obstetric Surveillance Study (NOSS) collaboration countries, Denmark, Finland, Iceland, Norway, Sweden, (click here or 2021.02.05.21250672v1.full). They probably include cases from studies 20, 88, 256, 259b, 278, 282, 298, 299, 341, 523 and 588. Citation: Hilde Engjom, Anna JM Aabakke, Kari Klungsøyr, Teresia Svanvik, Outi Äyräs, Eva Jonasdottir, Lars Thurn, Elin Jones, Karin Pettersson, Lill Trine Nyfløt, Iqbal Al-Zirqi, Siri Vangen, Pétur B. Júlíusson, Karin Källén, Mika Gissler, Lone Krebs. COVID-19 in pregnancy – characteristics and outcomes of pregnant women admitted to hospital because of SARS-CoV-2 infection in the Nordic countries. medRxiv 2021.02.05.21250672; doi: https://doi.org/10.1101/2021.02.05.21250672 [Registry] Update 24 April. Peer reviewed publication (click here or study). Citation: Engjom H, Aabakke AJ, Klungsøyr K, Svanvik T, Äyräs O, Jonasdottir E, Thurn L, Jones E, Pettersson K, Nyfløt LT, Al-Zirqi I, Vangen S, Júlíusson PB, Källén K, Gissler M, Krebs L. COVID-19 in pregnancy – characteristics and outcomes of pregnant women admitted to hospital because of SARS-CoV-2 infection in the Nordic countries. Acta Obstet Gynecol Scand. 2021 Apr 22. doi: 10.1111/aogs.14160. Epub ahead of print. PMID: 33885150.

11 February update – studies 608 and 609 added

Study 609 – 1,291 cases from USA

These pregnant women with a positive SARS-CoV-2 test result were cared for in 33 National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network hospitals between March 1 and July 31, 2020 (click here or METZ Disease_Severity_and_Perinatal_Outcomes_of.121 (1)). The hospitals, listed here, include many which have previously reported cases. Citation: Metz, Torri D. MD, MS; Clifton, Rebecca G. PhD; Hughes, Brenna L. MD; Sandoval, Grecio MA; Saade, George R. MD; Grobman, William A. MD, MBA; Manuck, Tracy A. MD, MS; Miodovnik, Menachem MD; Sowles, Amber BSN, RN; Clark, Kelly BSN, RN; Gyamfi-Bannerman, Cynthia MD, MS; Mendez-Figueroa, Hector MD; Sehdev, Harish M. MD; Rouse, Dwight J. MD; Tita, Alan T.N. MD, PhD; Bailit, Jennifer MD, MPH; Costantine, Maged M. MD; Simhan, Hyagriv N. MD; Macones, George A. MD; for the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network Disease Severity and Perinatal Outcomes of Pregnant Patients With Coronavirus Disease 2019 (COVID-19), Obstetrics & Gynecology: February 8, 2021 – Volume Latest Articles – Issue – 10.1097/AOG.0000000000004339 doi: 10.1097/AOG.0000000000004339

Study 608 – Case report from Saudi Arabia

From King Saud Medical City, Riyadh (click here or ccr3.3913). None of the newborns reported in study 554 from the same centre tested positive. Citation: Huseynova, RA, A. Bin Mahmoud, L, Huseynov, O, et al. A neonate born to an infected COVID‐19 mother was tested positive just 24 hours after its birth. Clin Case Rep. 2021; 00: 1– 4. https://doi.org/10.1002/ccr3.3913

10th February update – studies 606 and 607 added

Study 607 – 317 cases from Spain

Pregnant women with anti SARS-CoV-2 &/or a positive RT-PCR, from three hospitals (Sant Joan de Déu, Hospital Clinic Barcelona, and Hospital de Sant Pau) in Barcelona (click here or CROVETTO ciab104 (1)). The details and hospitals suggest overlap with study 235. Citation: Francesca Crovetto, Fàtima Crispi, Elisa Llurba, Rosalia Pascal, Marta Larroya, Cristina Trilla, Marta Camacho, Carmen Medina, Carlota Dobaño, Maria Dolores Gomez-Roig, Francesc Figueras, Eduard Gratacos, KidsCorona Pregnancy COVID-19 group, Impact of SARS-CoV-2 Infection on Pregnancy Outcomes: A Population-Based Study, Clinical Infectious Diseases, 2021;, ciab104, https://doi.org/10.1093/cid/ciab104

Study 606 – IgG & IgA in breast milk from 18 cases in USA

The hospitals from which women were recruited is not stated. but from the ethics approvals included centres in Idaho, the University of Rochester Medical Center, New York, and Brigham & Women’s Hospital, Boston, Massachusetts (click here or mBio-2021-Pace-e03192-20.full). Citation: Pace RM, Williams JE, Järvinen KM, Belfort MB, Pace CDW, Lackey KA, Gogel AC, Nguyen-Contant P, Kanagaiah P, Fitzgerald T, Ferri R, Young B, Rosen-Carole C, Diaz N, Meehan CL, Caffé B, Sangster MY, Topham D, McGuire MA, Seppo A, McGuire MK. 2021. Characterization of SARS-CoV-2 RNA, antibodies, and neutralizing capacity in milk produced by women with COVID-19. mBio 12:e03192-20. https://doi.org/10.1128/mBio.03192-20.&nbsp;

9th February update – studies 603 to 605 added

Study 605 – Case report from Qatar

From the Women’s Wellness and Research Center, Hamad Medical Corporation, Doha, which also reported the case in study 577 (click here or ccr3.3886). However the clinical details differ. Citation: Khatib MY, Olagundoye VO, Elshafei MS, El Khatib FM, Mohamed AS, Nashwan AJ. Management considerations for a critically ill 26-gestational week patient with COVID-19: A case report. Clin Case Rep. 2021;00:1–4. https://doi.org/10.1002/ccr3.3886 [ITU, ventilation]

Study 604 – 39 cases from Turkey

Cared for at Ankara City Hospital (click here or full text not available). Likely overlap with studies 203, 227, 244, 399, 444, 512, & 569. Citation: Erol Koç, Esin Merve, Fındık, Rahime Bedir, Akkaya, Hatice, Karadağ, Işılay, Tokalıoğlu, Eda Özden and Tekin, Özlem Moraloğlu. “Comparison of hematological parameters and perinatal outcomes between COVID-19 pregnancies and healthy pregnancy cohort” Journal of Perinatal Medicine, vol. 49, no. 2, 2021, pp. 141-147. https://doi.org/10.1515/jpm-2020-0403 [control group]

Study 603 – 35 cases from Austria

Cared for at Clinik Ottakring, in Vienna, which has not previously reported cases (click here or full text not available). Citation: Hall, Mirijam, Endress, David, Hölbfer, Susanne and Maier, Barbara. “SARS-CoV-2 in pregnancy: maternal and perinatal outcome data of 34 pregnant women hospitalised between May and October 2020” Journal of Perinatal Medicine, vol. 49, no. 2, 2021, pp. 138-140. https://doi.org/10.1515/jpm-2020-0499&nbsp;

7th February update – studies 599 to 602 added

Study 602 – case report from United Arab Emirates

A woman contracted Covid-19 at 26 weeks gestation and required ventilation and five days of ECMO therapy (click here or Tambawala e240823.full). She recovered and the pregnancy is continuing. Cared for at Dubai Hospital, which has not previously reported cases. Citation: Tambawala ZY, Hakim ZT, Hamza LK, et al. Successful management of severe acute respiratory distress syndrome due to COVID-19 with extracorporeal membrane oxygenation during mid-trimester of pregnancy. BMJ Case Reports CP 2021;14:e240823.

Study 601 – 34 cases from USA

Cared for at Hutzel Women’s Hospital, Detroit, Michigan, between March 11, 2020 and July 31, 2020 (click here or 10-1055-s-0040-1721673). This hospital has not previously reported cases. Citation: Jani S, Jacques SM, Qureshi F, et al. Clinical Characteristics of Mother-Infant Dyad and Placental Pathology in COVID-19 Cases in Predominantly African American Population. AJP Rep. 2021;11(1):e15-e20. doi:10.1055/s-0040-1721673

Study 600 – 171 cases from USA

Of 171 pregnant women hospitalised with Covid-19, 21 were admitted to ICU and 3 died (click here or 2021.01.29.21250788v1.full). They were cared for at the University of California affiliated hospitals of Davis, Irvine, Los Angeles, San Diego, and San Francisco, so likely overlap with study 323. Citation: Miriam Nuño, Yury García, Ganesh Rajasekar, Diego Pinheiro, Alec J. Schmidt. COVID-19 Hospitalizations in Five California Hospitals. medRxiv 2021.01.29.21250788; doi: https://doi.org/10.1101/2021.01.29.21250788

Study 599 – 116 seropositive women and 12 RT-PCR positive in USA

Of 708 pregnant women cared for at the Mount Sinai and Mount Sinai West hospitals in New York, from April 20, 2020 and delivered by 15 August, 116 were seropositive, and 12 RT-PCR positive (click here or 2021.02.01.21250943v1.full (1)). They likely overlap with studies 86, 119,131, 135, 160, 240, 412, 455, & 457. Citation: Nina M. Molenaar, Anna-Sophie Rommel, Lotje de Witte, Siobhan M. Dolan, Whitney Lieb, Erona Ibroci, Sophie Ohrn, Jezelle Lynch, Christina Capuano, Daniel Stadlbauer, Florian Krammer, Lauren B. Zapata, Rachel I. Brody, Rhoda S. Sperling, Omara Afzal, Mr Roy Missall, Amy Balbierz, Teresa Janevic, Joanne Stone, Elizabeth A. Howell, Veerle Bergink. Seroprevalence of SARS-CoV-2 during pregnancy and associated outcomes: results from an ongoing prospective cohort study, New York City. medRxiv 2021.02.01.21250943; doi: https://doi.org/10.1101/2021.02.01.21250943

3rd February update – study 598 added

Study 598 – 100 mothers, 101 babies from USA

From New York–Presbyterian’s Morgan Stanley Children’s Hospital and Allen Hospital from March 13 to April 24, 2020 (click here or jamapediatrics_dumitriu_2020_oi_200070_1611604165.97231 (1)). Both hospitals are affiliated with Columbia University Irving Medical Center. The authors note that they include 14 previously reported cases in study 27. There may also be overlap with studies 14, 41, 95, 96, 136, 160, 216, 230, 234, 261, and 276. Citation: Dumitriu D, Emeruwa UN, Hanft E, et al. Outcomes of Neonates Born to Mothers With Severe Acute Respiratory Syndrome Coronavirus 2 Infection at a Large Medical Center in New York City. JAMA Pediatr. 2021;175(2):157–167. doi:10.1001/jamapediatrics.2020.4298

1st February update – studies 592 to 597 added. Study 3 withdrawal noted.

Studies 593 to 597 – SMFM 2021 posters

Posters presented at the Society for Maternal Fetal Medicine virtual conference, 25 to 30 January, 2021 (SMFM 2021). Study 593– 52 patients from McGill University Medical Centre and the Jewish Genereal Hospital, Montreal, Quebec, Canade . Study 594 – 10 cases from University of Toledo, Ohio, USA . Study 595 – 29 cases from University of New Mexico Hospital, Albuquerque, New Mexico, USA . Study 596 – 11 cases from The Rotunda Hospital, Dublin, Ireland . Study 597 – 15 cases (two deaths) from the University of Mississippi Medical Center, Jackson, Mississippi, USA .  Citations to the AJOG abstracts to be added.

Study 592 – Case report from Italy

From Santo Stefano Hospital, Prato (click here or jmv.26609). The clinical features suggest this is case 2 in study 367. Citation: Cavaliere AF, Marchi L, Aquilini D, Brunelli T, Vasarri PL. Passive immunity in newborn from SARS-CoV-2-infected mother. J Med Virol. 2020 Oct 19. doi: 10.1002/jmv.26609. Epub ahead of print. PMID: 33073377.

31 January update – study 589 to 591 added

Study 591 – antibody transfer in 22 mother infant dyads from USA

SARS-CoV-2-specific antibody transfer is reduced compared to influenza- and pertussis-specific antibodies, and cord titers and functional activity is lower than in maternal plasma, in 22 maternal: cord dyads from SARS-CoV-2 positive mothers in third trimester (click here or PIIS0092867420317499). From Boston Massachusetts. Citation: Atyeo C, Pullen KM, Bordt EA, Fischinger S, Burke J, Michell A, Slein MD, Loos C, Shook LL, Boatin AA, Yockey LJ, Pepin D, Meinsohn MC, Nguyen NMP, Chauvin M, Roberts D, Goldfarb IT, Matute JD, James KE, Yonker LM, Bebell LM, Kaimal AJ, Gray KJ, Lauffenburger D, Edlow AG, Alter G. Compromised SARS-CoV-2-specific placental antibody transfer. Cell. 2020 Dec 23:S0092-8674(20)31749-9. doi: 10.1016/j.cell.2020.12.027. Epub ahead of print. PMID: 33476549; PMCID: PMC7755577. [important]

Study 590 – antibody levels in 83 mother/infant dyads from USA

Anti-SARS-CoV-2 IgG crosses the placenta (click here or jamapediatrics_flannery_2021_oi_210002_1611680224.61476). From Pennsylvania Hospital in Philadelphia, so may overlap with studies 65, 175, 202, 221, 350, 359 and 496. Citation: Flannery DD, Gouma S, Dhudasia MB, et al. Assessment of Maternal and Neonatal Cord Blood SARS-CoV-2 Antibodies and Placental Transfer Ratios. JAMA Pediatr. Published online January 29, 2021. doi:10.1001/jamapediatrics.2021.0038 [important]

Study 589 – 1,150 cases from Spain

No association between past flu & Tdap vaccination status, and severity of SARS-CoV-2 in pregnancy (click here or vaccines-09-00031). From the 78 Spanish Obstetric Emergency Group hospitals. Citation: de la Cruz Conty ML, Encinas Pardilla MB, Garcia Sanchez M, Gonzalez Rodriguez L, Muner-Hernando ML, Royuela Vicente A, Pintado Recarte P, Martinez Varea A, Martinez Diago C, Cruz Melguizo S, Martinez-Perez O, On Behalf Of The Spanish Obstetric Emergency Group. Impact of Recommended Maternal Vaccination Programs on the Clinical Presentation of SARS-CoV-2 Infection: A Prospective Observational Study. Vaccines (Basel). 2021 Jan 8;9(1):31. doi: 10.3390/vaccines9010031. PMID: 33429912; PMCID: PMC7826802.

30 January update – studies 582 to 588 added

Study 588 – Case report from Sweden

From either Lund or Malmo (click here or main (13)). The clinical details differ from study 259b. Citation: Kolkova Z, Bjurström MF, Länsberg JK, Svedas E, Hamer MA, Hansson SR, Herbst A, Zaigham M. Obstetric and intensive-care strategies in a high-risk pregnancy with critical respiratory failure due to COVID-19: A case report. Case Rep Womens Health. 2020 Jul 8;27:e00240. doi: 10.1016/j.crwh.2020.e00240. PMID: 32714844; PMCID: PMC7340590.

Study 587 – 0/67 tested pregnant women from South Africa

From Kalafong Provincial Tertiary Hospital in Atteridgeville, Pretoria. Abstract only (click here). Citation: N. Mopane F. Molokoane M. Mojela L. Seopela L.C. Snyman. First results of universal SARS-CoV-2 virus testing of asymptomatic pregnant patients presenting for antenatal care at the Kalafong Provincial Tertiary Hospital. Obstetrics and Gynaecology Forum Vol. 30, No. 2 Jan 2020

Study 586 – Case report from France

From Service de Gynécologie-Obstétrique, Centre Fédératif de Pelvi-Périnéologie, CHU de Nantes, Nantes (click here or main (12)). Citation: Smati S, Mahot P, Bourdiol A, Ploteau S, Hadjadj S, Cariou B. Euglycaemic ketoacidosis during gestational diabetes with concomitant COVID-19 infection. Diabetes Metab. 2020 Jul 29:S1262-3636(20)30100-2. doi: 10.1016/j.diabet.2020.07.008. Epub ahead of print. PMID: 32738403; PMCID: PMC7387919.

Study 585 – Case report from India

From Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi, Wardha, Maharashtra (click here or 2838-Article Text-7183-1-10-20200818 (1)). Citation: Priyanka Singh, Neema Acharya, & Neha Verma. (2020). Experience of managing covid-19 suspected case in labour in a green zone district tertiary care hospital. International Journal of Research in Pharmaceutical Sciences, 11(SPL1), 500-505. https://doi.org/10.26452/ijrps.v11iSPL1.2838

Study 584 – case report from Iran

From Imam Ali Hospital, Alborz University of Medical Sciences, Karaj (click here or main (11)). Citation: Motlagh AJ, Esmaelzadeh Saeieh S, Parhigar O, Salehi L. An asthmatic pregnant woman with COVID-19: A case report study. Respir Med Case Rep. 2020;31:101296. doi: 10.1016/j.rmcr.2020.101296. Epub 2020 Nov 19. PMID: 33240787; PMCID: PMC7676370.

Study 583 – case report from Spain

From Hospital Universitario 12 de Octubre, Madrid (click here or main (10)). Citation: López Pérez V, Cora Vicente J, Echevarría Granados C, Salcedo Vázquez ML, Estol F, Tebar Cuesta MY. Postpartum consciousness disturbance: can covid-19 cause posterior reversible encephalopathy syndrome? Rev Esp Anestesiol Reanim. 2020 Nov;67(9):511-515. English, Spanish. doi: 10.1016/j.redar.2020.06.008. Epub 2020 Jul 14. PMID: 33036761; PMCID: PMC7359790.

Study 582 – Case report from India

From Dr. RML Hospital, New Delhi, which has not previously reported cases  (click here or fmaa094). Citation: Bandyopadhyay T, Sharma A, Kumari P, Maria A, Choudhary R. Possible Early Vertical Transmission of COVID-19 from an Infected Pregnant Female to Her Neonate: A Case Report. J Trop Pediatr. 2020 Nov 22:fmaa094. doi: 10.1093/tropej/fmaa094. Epub ahead of print. PMID: 33221859; PMCID: PMC7717437.

29th January – studies 574 to 581 added

Study 581 – Placental analysis of 39 cases from USA

From Yale New Haven Hospital so probably overlap with studies 132, 155 and 314 (click here or 2021.01.25.21250452v1.full). Citation: Alice Lu-Culligan, Arun R. Chavan, Pavithra Vijayakumar, Lina Irshaid, Edward M. Courchaine, Kristin M. Milano, Zhonghua Tang, Scott D. Pope, Eric Song, Chantal B.F. Vogels, William J. Lu-Culligan, Katherine H. Campbell, Arnau Casanovas-Massana, Santos Bermejo, Jessica M. Toothaker, Hannah J. Lee, Feimei Liu, Wade Schulz, John Fournier, M. Catherine Muenker, Adam J. Moore, Yale IMPACT Team, Liza Konnikova, Karla M. Neugebauer, Aaron Ring, Nathan D. Grubaugh, Albert I. Ko, Raffaella Morotti, Seth Guller, Harvey J. Kliman, Akiko Iwasaki, Shelli F. Farhadian. SARS-CoV-2 infection in pregnancy is associated with robust inflammatory response at the maternal-fetal interface. medRxiv 2021.01.25.21250452; doi: https://doi.org/10.1101/2021.01.25.21250452

Study 580 – 2,126 cases from Brazil

From the Brazilian Ministry of Health, “severe acute respiratory syndrome” tracking database (click here or 2021.01.22.21250346v1.full). For pregnancies see table 1. Likely overlap with studies 66, 138, 182, 194, 201, 213, 248, 249, 278, 309, 358, 426, 552, and 565. Citation: Eduardo Pietre, Gabriel P Amorim, Maria F F Bittencourt, Marcelo Ribeiro-Alves, Mariana Acquarone Prevalent comorbidities among young and underprivileged: Death portrait of COVID-19 among 235 555 hospitalized patients in Brazil. medRxiv 2021.01.22.21250346; doi: https://doi.org/10.1101/2021.01.22.21250346

Study 579 – 22 cases from USA

The authors are from Washington University in St. Louis, Missouri (click here or 1-s2.0-S2589933321000148-main). If the unnamed hospital was Barnes Jewish these cases may overlap with studies 69, 259 and 290. Citation: Megan C. OAKES MD , Annessa S. KERNBERG MD , Ebony B. CARTER MD MPH , Megan E. FOELLER MD , Arvind PALANISAMY MD FRCA , Nandini RAGHURAMAN MD MS , Jeannie C. KELLY MD MS , Pregnancy as a risk factor for severe coronavirus 2019 (COVID-19) disease using standardized clinical criteria, American Journal of Obstetrics & Gynecology MFM (2021), doi: https://doi.org/10.1016/j.ajogmf.2021.100319

Study 578 – serology of 88 cases from USA

From New York-Presbyterian Hospital, Weill Cornell, so probably overlapping with many previous studies (click here or 1-s2.0-S0002937821000533-main). Citation: Kubiak JM, Murphy EA, Yee J, Cagino K, Friedlander RL, Glynn SM, Matthews KC, Jurkiewicz M, Sukhu AC, Zhao Z, Prabhu M, Riley L, Yang YJ, SARS-CoV-2 serology levels in pregnant women and their neonates., American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.01.016.

Study 577 – Case report from Qatar

From Women’s Wellness and Research Center, Hamad Medical Corporation, Doha, which has not previously reported cases (click here or ccr3.3485). Probably included in studies 364 and 407. Citation: Yaqoub, S, Ahmad, S, Mansouri, Z, et al. Management of life‐threatening acute respiratory syndrome and severe pneumonia secondary to COVID‐19 in pregnancy: A case report and literature review. Clin Case Rep. 2021; 9: 137– 143. https://doi.org/10.1002/ccr3.3485

Study 576 – 9 ECMO cases from USA & Italy

From Houston, Iowa, New York, Boston and Bergamo (click here or Successful_Treatment_of_Pregnant_and_Postpartum.4). Citation: Barrantes JH, Ortoleva J, O’Neil ER, Suarez EE, Beth Larson S, Rali AS, Agerstrand C, Grazioli L, Chatterjee S, Anders M. Successful Treatment of Pregnant and Postpartum Women With Severe COVID-19 Associated Acute Respiratory Distress Syndrome With Extracorporeal Membrane Oxygenation. ASAIO J. 2021 Feb 1;67(2):132-136. doi: 10.1097/MAT.0000000000001357. PMID: 33229971.

Study 575 – 66 cases from Russia

Cared for at the National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of Russian Federation in Moscow which has not previously reported cases (click here or IJMF_0_1850683). Possible inclusion in study 278. Citation: Shmakov RG, Prikhodko A, Polushkina E, Shmakova E, Pyregov A, Bychenko V, Priputnevich TV, Dolgushin GO, Yarotskaya E, Pekarev O, Bolibok N, Degtyarev D, Sukhikh GT. Clinical course of novel COVID-19 infection in pregnant women. J Matern Fetal Neonatal Med. 2020 Nov 29:1-7. doi: 10.1080/14767058.2020.1850683. Epub ahead of print. PMID: 33249969; PMCID: PMC7711745.

Study 574 – Case report from Italy

From University Hospital, Modena, so probably included in studies 64, 117 and 252 (click here or R09Y9999N00A20113005). Citation: Sileo FG, Tramontano AL, Leone C, Meacci M, Gennari W, Ternelli G, La Marca A, Lugli L, Berardi A, Facchinetti F, Bertucci E. Pregnant woman infected by Coronavirus Disease (COVID-19) and calcifications of the fetal bowel and gallbladder: a case report. Minerva Ginecol. 2020 Nov 30. doi: 10.23736/S0026-4784.20.04717-6. Epub ahead of print. PMID: 33249821.

28th January – studies 570 to 573 added

Study 573 – 240 cases from USA

From 35 sites in Washington State (click here or 1-s2.0-S0002937821000338-main). These cases overlap with those in studies 83, 102, 139 and 389. Citation: Lokken EM, Huebner EM, Taylor GG, Hendrickson S, Vanderhoeven J,Kachikis A, Coler B, Walker CL, Sheng JS, al-Haddad BJS, McCartney SA, Kretzer NM, Resnick R,Barnhart N, Schulte V, Bergam B, Ma KK, Albright C, Larios V, Kelley L, Larios V, Emhoff S, Rah J,Retzlaff K, Thomas C, Paek BW, Hsu RJ, Erickson A, Chang A, Mitchell T, Hwang JK, Erickson S,Delaney S, Archabald K, Kline CR, LaCourse SM, Adams Waldorf KM, For the Washington StateCOVID-19 in Pregnancy Collaborative, Disease Severity, Pregnancy Outcomes and Maternal Deaths among Pregnant Patients with SARS-CoV-2 Infection in Washington State, American Journal ofObstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2020.12.1221.

Study 572 – Case report from Romania

From ‘Dr Carol Davila’ Central Military Emergency University Hospital, Bucharest, which has not previously reported cases (click here or etm_21_1_9524_PDF). Citation: Florea AA, Sirbu CA, Ghinescu MC, Plesa CF, Sirbu AM, Mitrica M and Ionita‑Radu F: SARS‑CoV‑2, multiple sclerosis, and focal deficit in a postpartum woman: A case report. Exp Ther Med 21: 92, 2021

Study 571 – serological testing in Spain

From Madrid (click here or pone.0243029). Overlap with study 458. Citation: Villalaı´n C, HerraizI, Luczkowiak J, Pe´rezRivilla A, Folgueira MD, Mejı´a I, et al. (2020) Seroprevalence analysis of SARS-CoV-2 in pregnant women along the first pandemic outbreak and perinatal outcome. PLoS ONE 15(11): e0243029. https://doi.org/10.1371/journal. pone.0243029

Study 570 – 1,120 cases from USA

Abstract reporting 1,129 pregnant cases from Los Angeles county (click here or 1-s2.0-S0027968420302765-main). Of those who have given birth no neonates tested positive. Citation: L. Khadijah Lang, Covid-19 Maternal-Neonate Vertical Transmission Rates in Los Angeles County, Journal of the National Medical Association, Volume 112, Issue 5, Supplement, 2020, Pages S36-S37, ISSN 0027-9684, https://doi.org/10.1016/j.jnma.2020.09.093. (http://www.sciencedirect.com/science/article/pii/S0027968420302765)

27th January – studies 567 to 569 added

Study 569 – 39 cases from Turkey

Cared for at Ankara City Hospital so probably overlap with studies 203, 223, 244, 399, 444 and 512 (click here or [16193997t). Citation: Erol Koç, E. M., Fındık, R. B., Akkaya, H., Karadağ, I., Tokalıoğlu, E. Ö., & Tekin, Ö. M. (2020). Comparison of hematological parameters and perinatal outcomes between COVID-19 pregnancies and healthy pregnancy cohort, Journal of Perinatal Medicine (published online ahead of print 2020), 000010151520200403. doi: https://doi.org/10.1515/jpm-2020-0403

Study 568 – Case report from USA

Conference poster from Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY which has not previously reported cases (click here or ). Citation: Wander Praneet, He Qiu, Ceena Chandrabos, David Bernstein, Sanjaya Satapathy. P2162 (S2415). – COVID-19 Infection Presenting as Acute Hepatitis in a 22-Week Pregnant Woman. American Journal of Gastroenterology. Conference: 2020 Annual Scientific Meeting of the American College of Gastroenterology, ACG 2020. 115 (SUPPL) (pp S1282), 2020. Date of Publication: October 2020. AN: 633658549

Study 567 – Case report from USA

Cared for at Loyola University Medical Center, Chicago, Illinois, which has not previously reported cases (click here or S2301_COVID_19_and_Ulcerative_Colitis_in_Pregnancy.2301). Citation: Lewine, Eliza MD1; Trieu, Judy MD, MPH2; Asamoah, Nikiya MD2; Venu, Mukund MD, FACG2; Naik, Amar MD2 S2301 COVID-19 and Ulcerative Colitis in Pregnancy, The American Journal of Gastroenterology: October 2020 – Volume 115 – Issue – p S1217 doi: 10.14309/01.ajg.0000711252.28660.fc

26th January – studies 550 to 566 added

Study 566 – Two cases from Bangladesh

One pregnant woman with Covid-19 survived. The other died (click here or JSAFOG-12-258). They were both cared for at Chittagong Medical College Hospital, Chattogram, which has not previously reported cases. Citation: Rashid F, Shahnaz S, Sharmin R, et al. Pregnancy with COVID-19: Weal and Woe. J South Asian Feder Obst Gynae 2020;12(4):258–260.

Study 565 – Case report from Brazil

Cared for at Fundação Hospital de Clínicas Gaspar Vianna, Belém, Pará state, which has not previously reported cases (click here or en_1678-4170-abc-115-05-0936). Citation: HOLANDA, Lucianna Serfaty de et al. Infecção por COVID-19 em Gestante Cardiopata. Arq. Bras. Cardiol. [online]. 2020, vol.115, n.5 [cited 2021-01-26], pp.936-938. Available from: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2020001300936&lng=en&nrm=iso&gt;. Epub Dec 07, 2020. ISSN 1678-4170. http://dx.doi.org/10.36660/abc.20200517.

Study 564 – Case report from Iran

Cared for at Urmia University of Medical Sciences, Urmia, which has not previously reported cases (click here or archcid-15-5-104394). Citation: Zarrintan A, Boeoofeh B , Rabieipour M , Mohammadi A, Khademvatani K, et al. Pulmonary Thromboembolism in a Pregnant Patient with Severe COVID19: A Novel Case Report and Review of Literature, Arch Clin Infect Dis. 2020 ; 15(5):e104394. doi: 10.5812/archcid.104394.

Study 563 – Case report from USA

From School of Medicine and Public Health, University of Wisconsin, Madison, which has not previously reported cases (click here or 1-s2.0-S221491122030103X-main). Citation: Jennifer Jacobson, Kathleen Antony, Michael Beninati, William Alward, Kara K. Hoppe, Use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe COVID-19 infection in pregnancy: A case report, Case Reports in Women’s Health, Volume 29, 2021, e00273, ISSN 2214-9112, https://doi.org/10.1016/j.crwh.2020.e00273. (http://www.sciencedirect.com/science/article/pii/S221491122030103X

Study 562 – Case report from India

From Lokmanya Tilak Muncipal General Hospital, Mumbai (click here or JSAFOG-12-243) so probably included in study 245. Citation: Mevada SA, Mehendale MA, Nayak AH, et al. Cardiomyopathy in Pregnancy with COVID-19: An Enigma. J South Asian Feder Obst Gynae 2020;12(4):243–244

Study 561- Case report from USA

A mother with Covid-19 gave birth to a baby with an ischaemic upper limb (click here or [21928959 – Case Reports in Perinatal Medicine] Neonate born with ischemic limb to a COVID-19 positive mother_ management and review of literature). The baby was cared for at Zucker School of Medicine at Hofstra, Northwell, New York. Citation: Perveen, S., Millington, K. A., Acharya, S., Grag, A., & Boyar, V. (2021). Neonate born with ischemic limb to a COVID-19 positive mother: management and review of literature, Case Reports in Perinatal Medicine, 10(1), 20200086. doi: https://doi.org/10.1515/crpm-2020-0086

Study 560 – 25 cases from France

Cared for at Cochin Hospital (Port-Royal Maternity) Paris (click here or 1-s2.0-S2468784720304177-main). Probably included in studies 150, 161 and 239. Citation: Tsatsaris V, Mariaggi AA, Launay O, Couffignal C, Rousseau J, Ancel PY, Marcault E, Ville Y, Cordier AG, Vivanti A, Carrara J, Luton D, Dommergues M, Borie C, Kayem G, Alessandrini V, Lecomte L, Meritet JF, Leruez-Ville M, Goffinet F, Dubois C, Picone O, Vauloup Fellous C. SARS-COV-2 IgG antibody response in pregnant women at delivery. J Gynecol Obstet Hum Reprod. 2020 Dec 10;50(7):102041. doi: 10.1016/j.jogoh.2020.102041. Epub ahead of print. PMID: 33310133.

Study 559 – 22 cases from China

Cared for at Tongji hospital, Wuhan (click here or 1-s2.0-S0924857920304805-main (1)). Previously reported many times. Citation: He Z, Fang Y, Zuo Q, Huang X, Lei Y, Ren X, Liu D. Vertical transmission and kidney damage in newborns whose mothers had coronavirus disease 2019 during pregnancy. Int J Antimicrob Agents. 2020 Dec 9:106260. doi: 10.1016/j.ijantimicag.2020.106260. Epub ahead of print. PMID: 33309765.

Study 558 – 19 cases from Uzbekistan

Abstract only (click here). Cared for in Kagan maternity hospital in Bukhara which has not previously reported cases. Citation: GULCHEKHRA A, IKHTIYAROVA, NIGORA K. DUSTOVA, MAVLYUDA A. KHASANOVA, GULRUKH S. SULEYMANOVA, SALIM S. DAVLATOV. Pathomorphological changes of the placenta in pregnant women infected with coronavirus covid-19 International Journal of Pharmaceutical Research ; 13(1):1935-1942, 2021.

Study 557 – case report from Kyrgyzstan

Cared for at City Maternity Hospital No. 2, 225 Moskva Street, Bishkek-720010, which has not previously reported cases (click here or 341-Article Text-592-1-10-20210107). Citation: Zhumabekova A, Tagaev T, Yethindra V, Zhumabaeva S, Ysabaeva D, Imankulova B. A case report of a pregnant woman with coronavirus disease 2019 (COVID-19) and her live-born infant. Biomedicine [Internet]. 2021Jan.1 [cited 2021Jan.26];40(4):551-3. Available from: https://biomedicineonline.org/index.php/home/article/view/341

Study 556 – case report from Iran

Cared for at Vasei Hospital, Sabzevar University of Medical Sciences, Sabzevar, which has not previously reported cases (click here or Tanaffos-19-152). Citation: Pourdowlat G, Mikaeilvand A, Eftekhariyazdi M, Nematshahi M, Ebrahimi M, Kazemzadeh A. Prone-Position Ventilation in a Pregnant Woman with Severe COVID-19 Infection Associated with Acute Respiratory Distress Syndrome. Tanaffos. 2020;19(2):152-155.

Study 555 – 56 cases from Iran

Cared for at Nekouei-Hedayati-Forqani Hospital in Qom which has not previously reported cases (click here or 32025-Article Text-134703-5-10-20210108 (2)). Citation: Mirzaie M, Shafie H, Heidarifar R, Yousefi MS, Yousefi MS. Relationship between ABO Blood Group Type and COVID-19 Outcome in Pregnant Women. J Cell Mol Anesth [Internet]. 2020Sep.23 [cited 2021Jan.26];5(4):282-3. Available from: https://journals.sbmu.ac.ir/jcma/article/view/32025

Study 554 – 4 cases from Saudi Arabia

Cared for at King Saud University Medical City, Riyadh which has not previously reported cases (click here or JEGH-10-3-214). Citation: Barry M, AlMohaya A, AlHijji A, Akkielah L, AlRajhi A, Almajid F, Alsharidi A, Al-Shahrani FS, Alotaibi NH, Alanazi A, Ghonem L, Alhetheel A, Alsubaie S, Memish ZA. Clinical Characteristics and Outcome of Hospitalized COVID-19 Patients in a MERS-CoV Endemic Area. J Epidemiol Glob Health. 2020 Sep;10(3):214-221. doi: 10.2991/jegh.k.200806.002. PMID: 32954712; PMCID: PMC7509106.

Study 553 – 29 cases from USA

Screened at University of Illinois at Chicago which has not previously reported cases (click here or 10-1055-s-0040-1721416). Citation: Buhimschi CS, Elam GL, Locher SR, Norris-Stojak D, Aldasoqi H, Stephenson MD, Buhimschi IA. Prevalence and Neighborhood Geomapping of COVID-19 in an Underserved Chicago Pregnant Population. AJP Rep. 2020 Oct;10(4):e413-e416. doi: 10.1055/s-0040-1721416. Epub 2020 Dec 3. PMID: 33294287; PMCID: PMC7714615.

Study 552 – Case report from Brazil

Cared for at Hospital Universitário da Universidade Federal do Maranhão, São Luis, MA. which has not previously reported cases (click here or 1806-9282-ramb-66-12-1621). Citation: PESSOA, Fabrício Silva et al. Probable vertical transmission identified within six hours of life. Rev. Assoc. Med. Bras. [online]. 2020, vol.66, n.12 [cited 2021-01-26], pp.1621-1624. Available from: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302020001201621&lng=en&nrm=iso&gt;. Epub Dec 16, 2020. ISSN 1806-9282. https://doi.org/10.1590/1806-9282.66.12.1621.

Study 551 – Case report from USA

A maternal death from Covid-19 treated at St. Joseph’s University Medical Center, Paterson, New Jersey, which has not previously reported cases (click here or amjcaserep-21-e926591). Citation: Patel P, Kulkarni S, Guerrero M, Persaud C, Zuberi J, Rebein B. Emergency Cesarean Section at 38 Weeks of Gestation with COVID-19 Pneumonia: A Case Report. Am J Case Rep. 2020 Dec 19;21:e926591. doi: 10.12659/AJCR.926591. PMID: 33339814; PMCID: PMC7755590.

Study 550 – 67 cases from USA

From Massachusetts General Hospital, Boston (click here or ofaa524). Overlap with studies 142, 231, 262, 519, 531. Citation: M D Soffer, L L Shook, K James, M R Sawyer, A Ciaranello, R Mahrouk, S N Bernstein, A A Boatin, A G Edlow, C York-Best, A J Kaimal, I T Goldfarb, Protocol-Driven Intensive Outpatient Management of Pregnant Patients With Symptomatic Coronavirus Disease 2019, Open Forum Infectious Diseases, Volume 7, Issue 11, November 2020, ofaa524, https://doi.org/10.1093/ofid/ofaa524

24th January – studies 547 to 549 added

Study 549 – 32 cases from UK

These 32 women with Covid-19 in pregnancy were cared for at Newham University Hospital in London which has not previously reported cases (click here or 1753495×20985403). One woman died. They are included in the UKOSS reports. Citation: Milln J, Heard S, Gunganah K, Velauthar L, Saeed F. Clinical characteristics and pregnancy outcomes of women diagnosed with SARS-CoV-2 in London’s most ethnically diverse borough: A cross-sectional study. Obstetric Medicine. January 2021. doi:10.1177/1753495X20985403

Study 548 – 279 cases from Spain

Of 279 women with SARS-Cov-2 cared for in the 42 hospitals of the Spanish Obstetric Emergency Group, 174 were asymptomatic, and are reported in this paper (click here or Cruz-Lemini viruses-13-00112). They likely overlap with many of the previous studies from Spain. Citation: Cruz-Lemini, M.; Ferriols Perez, E.; de la Cruz Conty, M.L.; Caño Aguilar, A.; Encinas Pardilla, M.B.; Prats Rodríguez, P.; Muner Hernando, M.; Forcen Acebal, L.; Pintado Recarte, P.; Medina Mallen, M.d.C.; et al. Obstetric Outcomes of SARS-CoV-2 Infection in Asymptomatic Pregnant Women. Viruses 2021, 13, 112. https://doi.org/10.3390/v13010112

Study 547 – 879 cases from India

This paper from Nair Hospital, Mumbai reports on five pregnant women with Covid-19 (out of 879 treated in that hospital) who also had heart disease (click here or Tilve India EJOG in press). They probably overlap with those in studies 225, 283 & 520, but the clinical details suggest no overlap with studies 369 & 501. Citation: Tilve A, Mahajan NN, Pandey A, Jnanananda B, Gadekar S, Mahale SD, Gajbhiye RK, Impact of COVID-19 on pregnant women with Rheumatic heart disease or Peripartum cardiomyopathy, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2021), doi:  https://doi.org/10.1016/j.ejogrb.2021.01.024

19 January – studies 545 and 546 added

Study 546 – 55,154 cases from the US

The CDC tracking data up to Jan 11th 2021 includes 55,154 pregnant women with Covid-19, of whom 66 (0.12%) had died (click here). Citation: Centres for Disease Control. Weekly COVID-19 Pregnancy Data updated January 11 2021, Accessed 19 Jan 2021. [important]

Study 545 – 3,928 cases from the Netherlands

January 6 update of NETHOSS registry includes 3,928 women with Covid-19 in pregnancy and further details (click here). 26 women were treated in ITU, 10 ventilated and one woman died. There is also a graph showing the first and second waves. Available here. Accessed 19 Jan 2021. [important]

18 January – study 544 added

Study 544 – 6,380 cases from US

Among these 6,380 women with Covid-19, 86 required ventilation and nine died (click here or jamainternal_jering_2021_ld_200094_1610581352.25094). They were identified from a multi-hospital database covering about 20% of the United States, so will overlap with other series. Citation: Jering KS, Claggett BL, Cunningham JW, et al. Clinical Characteristics and Outcomes of Hospitalized Women Giving Birth With and Without COVID-19. JAMA Intern Med. Published online January 15, 2021. doi:10.1001/jamainternmed.2020.9241

16 January – study 543 added

Study 543 – Case report from Ireland

A woman contracted COVID-19 at 36 weeks and was delivered by Caesarean (click here or 1-s2.0-S0143400421000205-main). Placental histology is described in detail. Mother and baby recovered. She was cared for at Cork University Maternity Hospital, which has not previously reported cases. Citation: Linehan L, O’Donoghue K, Dineen S, White J, Higgins JR, Fitzgerald B, SARS-CoV-2 Placentitis: An uncommon complication of maternal COVID-19, Placenta, https://doi.org/10.1016/j.placenta.2021.01.012.

14 January update – studies 540 to 542 added

Study 542 – 112 cases in ICU in UK

The 8 January ICNARC report includes 69 currently and 43 recently pregnant women in ICU with Covid-19 since 1 September 2020 (available here or ICNARC_COVID-19_Report_2021-01-08.pdf). 12 and 13 women respectively were ventilated. Citation: Intensive Care National Audit & Research Centre. ICNARC report on COVID-19 in critcal care: England, Wales and Northern Ireland 8 January 2021 Accessed 14 January 2021. https://www.icnarc.org/Our-Audit/Audits/Cmp/Reports&nbsp;

Study 541 – 73 cases from Spain

73 women with Covid-19 gave birth to 79 babies (click here or S1695403320305233). [Spanish. English abstract] No babies tested positive. From author affiliations they were probably cared for at Hospital General Universitario Gregorio Marañón, Madrid, so probably overlap with cases in studies 151 and 381. Citation: Gonzalo Solís-García, Ana Gutiérrez-Vélez, Isabel Pescador Chamorro, Elena Zamora-Flores, Sara Vigil-Vázquez, Elena Rodríguez-Corrales, Manuel Sánchez-Luna, Epidemiología, manejo y riesgo de transmisión de SARS-CoV-2 en una cohorte de hijos de madres afectas de COVID-19, Anales de Pediatría, 2020, ISSN 1695-4033, https://doi.org/10.1016/j.anpedi.2020.12.004. (http://www.sciencedirect.com/science/article/pii/S1695403320305233). Update 8 March For English language version (click here or SOlis Garcia Eng Ed An Pediatrica). English citation: Solís-García G, Gutiérrez-Vélez A, Pescador Chamorro I, Zamora-Flores E, Vigil-Vázquez S, Rodríguez-Corrales E, Sánchez-Luna M. Epidemiology, management and risk of SARS-CoV-2 transmission in a cohort of newborns born to mothers diagnosed with COVID-19 infection. An Pediatr (Engl Ed). 2021 Mar;94(3):173-178. doi: 10.1016/j.anpede.2020.12.006. Epub 2021 Jan 26. PMID: 33521167; PMCID: PMC7834971.

Study 540 – 9 cases from Israel

Of 1,326 asymptomatic pregnant women tested, 9 were positive for SARS-CoV-2 (click here or PIIS0002937821000259). No clinical details. From author affiliations they were probably cared for at Hadassah-Hebrew University Medical Center, Jerusalem, so may overlap with cases in study 330. Citation: Rottenstreich A, Zarbiv G, Kabiri D, Benenson S, Oster Y, Porat S, Sompolinsky Y, Reubinoff B, Rapid antigen detection testing for universal screening for SARS-CoV-2 in women admitted for delivery, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.01.002.

11 January update – studies 536 to 539 added

Study 539 -1,606 cases from UK and 2,398 from USA

This MedRxiv preprint describes 1,606 cases collected by the UK PanCovid registry and 2,398 from the US American Academy of Pediatrics Section on Neonatal Perinatal Medicine (AAP SONPM) National Perinatal COVID-19 Registry (click here or 2021.01.06.21249325v1.full). They likely overlap with other UK and US registries and reports. Citation: Edward Mullins, Mark Hudak, Jay Banerjee, Trace Getzlaff, Julia Townson, Kimberly Barnette, Rebecca Playle, Tom Bourne, Christoph Lees, PAN-COVID-investigators, National Perinatal COVID-19 Registry Study Group. Pregnancy and neonatal outcomes of COVID-19, co-reporting of common outcomes from the PAN-COVID and AAP SONPM registry. medRxiv 2021.01.06.21249325; doi: https://doi.org/10.1101/2021.01.06.21249325

23 Feb Update. Preprint in J Ultrasound Obstet Gynecol (click here or uog.23619). Cases reported from the AAP SONPM registry now 2,399. Two figures and four tables, referenced within, but missing from the MedRxiv preprint added. Citation: Mullins, E., Hudak, M.L., Banerjee, J., Getzlaff, T., Townson, J., Barnette, K., Playle, R., Bourne, T., Lees, C. on behalf of PAN‐COVID investigators and the National Perinatal COVID‐19 Registry Study Group (2021), Pregnancy and neonatal outcomes of COVID‐19: co‐reporting of common outcomes from PAN‐COVID and AAP SONPM registries. Ultrasound Obstet Gynecol. Accepted Author Manuscript. https://doi.org/10.1002/uog.23619

Study 538 – Case report from Iran

A woman who had recently delivered from a pregnancy complicated by pre-eclampsia contracted Covid-19 four days post-partum (click here or 1-s2.0-S2210778920301367-main). Despite intensive care and ventilation, she died on May 28th. She was cared for in Iranshahr University of Medical Sciences, Baluchestan, which has not previously reported cases. Citation: Fatemeh Azarkish, Firouzeh Sheikhi, Zohreh Mirkazehi, Saeed Kalkali, Paria Bameni Moghadam, Mahya Zahirniya, Preeclampsia and the crucial postpartum period for Covid-19 infected mothers: A case report, Pregnancy Hypertension, Volume 23, 2021, Pages 136-139, ISSN 2210-7789, https://doi.org/10.1016/j.preghy.2020.10.012. (http://www.sciencedirect.com/science/article/pii/S2210778920301367)

Study 537 – Case report of ECMO from USA

A woman with Covid-19 at 23 weeks gestation was treated with ECMO, and recovered (click here or mark ECMO pzaa189). From author affiliations she was likely treated at the University of Iowa Heart and Vascular Center, which has not previously reported pregnancy cases. However she may be included in study 535. Citation: Alex Mark, Jennifer P Crumley, Kristina L Rudolph, Kevin Doerschug, Anna Krupp, Maintaining Mobility in a Patient Who Is Pregnant and Has COVID-19 Requiring Extracorporeal Membrane Oxygenation: A Case Report, Physical Therapy, , pzaa189, https://doi.org/10.1093/ptj/pzaa189

Study 536 – 534 cases from Italy

This report, in Italian, includes 534 cases of Covid-19 in pregnancy, reported to the ITOSS registry between February 25th and July 10th 2020 (click here or itOSS 081-087_ART-Corsi (002)). There will be overlap with study 246. Citation: Edoardo Corsi, Alice Maraschini, Enrica Perrone, Michele Antonio Salvatore, Paola D’Aloja, Serena Donati, Gruppo di lavoro ItOSS COVID-194.  La preparedness dell’Italian obstetric surveillance system in occasione della pandemia da SARS-CoV-2: aspetti metodologici di uno studio di popolazione. (The preparedness of the Italian obstetric surveillance system in the response to the emergency of the SARS-CoV-2 pandemic: methodological aspects of a population-based study) Epidemiol Prev 2020; 44 (5-6) Suppl 2:81-87. doi: 10.19191/EP20.5-6.S2.089

8 January update – study 535 added

Study 535 – 22 pregnant women treated with ECMO

This series of people with Covid-19 treated with ECMO between Jan 16 and May 1, 2020, from 213 hospitals in 36 countries, includes 22 pregnant women (click here or PIIS0140673620320080). No separate outcome data. Citation: Barbaro, Ryan P, Alexander, Peta et al. Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry The Lancet, Volume 396, Issue 10257, 1071 – 1078.

7 January update – study 534 added

Study 534 – 145 cases from Italy

Of 145 pregnant women with SARS-CoV-2  infection, 116 were symptomatic (click here or DiGuardo2021_Article_PoorMaternalNeonatalOutcomesIn). Seven mothers and nine neonates died. They were cared for in two unnamed tertiary referral hospitals between March and July 2020. The authors are affiliated with one hospital in Calabria, in the south, two in Catania, Sicily and one in Vicenza in the North East. Ethics approval was from another hospital in Sicily. Assuming the two hospitals are in Sicily, these cases have probably not been reported. None of the author affiliations were with Palermo, study 355. Citation: Di Guardo F, Di Grazia FM, Di Gregorio LM, Zambrotta E, Carrara G, Gulino FA, Tuscano A, Palumbo M. Poor maternal-neonatal outcomes in pregnant patients with confirmed SARS-Cov-2 infection: analysis of 145 cases. Arch Gynecol Obstet. 2021 Jan 3:1–6. doi: 10.1007/s00404-020-05909-4. Epub ahead of print. PMID: 33389111; PMCID: PMC7778712.

6 January update – study 533 added

Study 533 – 1,148 cases from UK

This Medxiv preprint describes 1,148 pregnant women with SARS-CoV-2, 722 with symptoms. who were admitted to hospital (click here or UKOSS Preprint (002)).  Of 640 completed pregnancies, there were 16 pregnancy losses before 24 weeks, 5 stillbirths and 2 neonatal deaths. Eight mothers died. Collected from all 194 consultant-led obstetric units in the United Kingdom between 1st March and 31st August 2020, they therefore overlap with those reported in study 92. Citation: Nicola Vousden, Kathryn Bunch, Edward Morris, Nigel Simpson, Christopher Gale, Patrick O’Brien, Maria Quigley, Peter Brocklehurst, Jennifer J Kurinczuk, Marian Knight. The incidence, characteristics and outcomes of pregnant women hospitalized with symptomatic and asymptomatic SARS-CoV-2 infection in the UK from March to September 2020: a national cohort study using the UK Obstetric Surveillance System (UKOSS). medRxiv 2021.01.04.21249195; doi: https://doi.org/10.1101/2021.01.04.21249195 [important] Update 16 May. Peer review published (click here or study) Citation: Vousden N, Bunch K, Morris E, Simpson N, Gale C, O’Brien P, et al. (2021) The incidence, characteristics and outcomes of pregnant women hospitalized with symptomatic and asymptomatic SARS-CoV-2 infection in the UK from March to September 2020: A national cohort study using the UK Obstetric Surveillance System (UKOSS). PLoS ONE 16(5): e0251123. https://doi.org/10.1371/journal.pone.0251123

3 January update – studies 529 to 532 added

Study 532 – zero pregnancy cases in a city in Japan

All 1475 pregnant women and 1343 partners tested for COVID-19 by PCR in saliva in all 12 maternity facilities in Himeji city between May 29 and September 5, 2020 were negative (click here or jog.14591). Over the same period 74 non-pregnant patients had Covid-19 in the same city. Citation: Okamura S, Akamatsu N, Kitajima T, Nakabayashi K, Fukumoto S, Katayama T, Mizutani Y, Kiyomoto H, Yamada H. Screening of COVID-19 polymerase chain reaction tests using saliva for pregnant women and their partners in Himeji city. J Obstet Gynaecol Res. 2020 Dec 22. doi: 10.1111/jog.14591. Epub ahead of print. PMID: 33354868.

Study 531 – 68 cases from USA

This preprint includes 68 pregnant women with suspected or confirmed COVID-19 (click here or 2907ed6a-c4cd-4147-b0bd-a5c41c5afec6). They were recruited through social media. Authors are mostly affilated with Harvard Medical School or Massachusetts General Hospital. Citation: Mayopoulos G, Ein-Dor T, Li K, Chan S, Dekel S. Giving birth under hospital visitor restrictions: Heightened acute stress in childbirth in COVID-19 positive women. Res Sq [Preprint]. 2020 Dec 9:rs.3.rs-112882. doi: 10.21203/rs.3.rs-112882/v1. PMID: 33330856; PMCID: PMC7743075.

Study 530 – 70 cases from Iran

Of 70 pregnant women with COVID-19 hospitalized from early March to late April 2020, two mothers died (click here or aim-23-856). 15/32 births were premature but no other baby outcomes are reported. The patients were cared for in various unnamed hospitals in Guilan province. Author affiliations suggest that these included Al-Zahra Hospital, in Rasht, which has not previously reported cases. Shared authors suggest the maternal deaths may overlap with those reported in study 67. Citation: Kazemi Aski S, Sharami SH, Hosseinzadeh F, Hesni E, Dalil Heirati SF, Ghalandari M, Mousavi A. Risk Factors, Clinical Symptoms, Laboratory Findings and Imaging of Pregnant Women Infected with COVID-19 in North of Iran. Arch Iran Med. 2020 Dec 1;23(12):856-863. doi: 10.34172/aim.2020.114. PMID: 33356344.

Study 529 – Case report from the Netherlands

A woman with Covid-19 was delivered by Caesarean at 31 weeks (click here or piaa153). There was evidence of SARS-CoV-2 in the placenta and the baby developed complications of both prematurity and birth asphyxia. However the baby tested negative. They were cared for in Erasmus University Medical Center, Rotterdam, which has not previously reported cases. The case was probably included in the NETHOSS registry. Citation: Schoenmakers S, Snijder P, Verdijk RM, Kuiken T, Kamphuis SSM, Koopman LP, Krasemann TB, Rousian M, Broekhuizen M, Steegers EAP, Koopmans MPG, Fraaij PLA, Reiss IKM. Severe Acute Respiratory Syndrome Coronavirus 2 Placental Infection and Inflammation Leading to Fetal Distress and Neonatal Multi-Organ Failure in an Asymptomatic Woman. J Pediatric Infect Dis Soc. 2020 Dec 26:piaa153. doi: 10.1093/jpids/piaa153. Epub ahead of print. PMID: 33367801.

2 January update – studies 525-528 added

Study 528 – 16 cases from Singapore

16 pregnant women with COVID-19 cared for in 4 hospitals (abstract only click here). Citation: Mattar CN, Kalimuddin S, Sadarangani SP, Tagore S, Thain S, Thoon KC, Hong EY, Kanneganti A, Ku CW, Chan GM, Lee KZ, Yap JJ, Tan SS, Yan B, Young BE, Lye DC, Anderson DE, Yang L, Su LL, Somani J, Tan LK, Choolani MA, Chan JK. Pregnancy Outcomes in COVID-19: A Prospective Cohort Study in Singapore. Ann Acad Med Singap. 2020 Nov;49(11):857-869. PMID: 33381779.

Study 527 – 114 cases from Peru

114 pregnant women positive for SARS-CoV-2, between April 15 and May 10, 2020, who delivered in the National Perinatal Maternal Institute, Lima, which has not previously reported cases (English abstractonly click here). Three newborns died. Citation: Dávila-Aliaga C, Espínola-Sánchez M, Mendoza-Ibáñez E, Guevara-Ríos E, Torres-Marcos E, Hinojosa-Pérez R, Espinoza-Vivas Y, Álvarez-Carrasco R, Velásquez-Vásquez C, Meza-Santibáñez L, Gonzales-Carrillo O, Arango-Ochante P, Racchumí-Vela A, Saldaña-Díaz C. Resultados perinatales y serológicos en neonatos de gestantes seropositivas para SARS-CoV-2: estudio transversal descriptivo [Perinatal outcomes and serological results in neonates of pregnant women seropositive to SARS-CoV-2: A cross-sectional descriptive study]. Medwave. 2020 Dec 21;20(11):e8084. Spanish. doi: 10.5867/medwave.2020.11.8084. PMID: 33382393.

Study 526 – 35 pregnant women from Switzerland

There were 35 pregnant women in this preprint hospital registry study up to August 31st, 2020 (click here or 2020.12.10.20246884v2.full). One went to ICU. No mothers died. No baby outcomes were reported. They were cared for 20 hospitals listed in the paper, and may overlap with cases in studies 72, 310 & 427. Citation: Amaury Thiabaud, Anne Iten, Carlo Balmelli, Laurence Senn, Nicolas Troillet, Andreas Widmer, Domenica Flury, Peter W. Schreiber, Miriam Vázquez, Lauro Damonti, Michael Buettcher, Danielle Vuichard-Gysin, Christoph Kuhm, Alexia Cusini, Thomas Riedel, Yvonne Nussbaumer, Roman Gaudenz, Ulrich Heininger, Christoph Berger, Franziska Zucol, Sara Bernhard-Stirnemann, Natascia Corti, Petra Zimmermann, Anita Uka, Anita Niederer-Loher, Céline Gardiol, Maroussia Roelens, Olivia Keiser. SARS-CoV-2/COVID-19 hospitalised patients in Switzerland: a prospective cohort profile. medRxiv 2020.12.10.20246884; doi: https://doi.org/10.1101/2020.12.10.20246884

Study 525 – 41 cases from Canada

Of 41 pregnant women testing positive for SARS-CoV-2, 30 had symptoms (click here or montreal). Two women required ventilation. There were no maternal deaths. No baby outcomes were reported. They were cared for in the Jewish General Hospital in Montreal, Quebec, which has not previously reported cases. Citation: Trahan, Marie-Julie et al.Screening and Testing Pregnant Patients for SARS-CoV-2: First-Wave Experience of a Designated COVID-19 Hospitalization Centre in Montreal J Obstet Gynaecol Can 2020;36(00):1−5. https://doi.org/10.1016/j.jogc.2020.11.001

1 January – study 254 added

Study 524 – 30 cases from Spain

13 pregnant and 17 postpartum women with Covid-19 in this series collected between 15th March and 15th October (click here or 2020.12.10.20246959v2.full). The authors suggest that pregnancy infection was more common in the second wave. Citation: Simona Iftimie, Ana F. López-Azcona, Immaculada Vallverdú, Salvador Hernàndez-Flix, Gabriel de Febrer, Sandra Parra, Anna Hernández-Aguilera, Francesc Riu, Jorge Joven, Jordi Camps, Antoni Castro, REUSCOVID Study Group. First and second waves of coronavirus disease-19: A comparative study in hospitalized patients in Reus, Spain. medRxiv 2020.12.10.20246959; doi: https://doi.org/10.1101/2020.12.10.20246959

31 December – study 523 added

Study 523 – seropositivity in pregnancy in Sweden

This preprint reports that about 15% of randomly sampled asymptomatic pregnant women from the Stockholm area had antibodies to SARS-CoV-2 by December 2020 (click here or 2020.12.24.20248821v1.full). 96% at levels that would be expected to confer immunity. Citation: Xaquin Castro Dopico, Sandra Muschiol, Murray Christian, Leo Hanke, Daniel J. Sheward, Nastasiya F. Grinberg, Gordana Bogdanovic, Gerald M. Mcinerney, Tobias Allander, Chris Wallace, Ben Murrell, Jan Albert, Gunilla B. Karlsson Hedestam. Seropositivity in blood donors and pregnant women during 9-months of SARS-CoV-2 transmission in Stockholm, Sweden. medRxiv 2020.12.24.20248821; doi: https://doi.org/10.1101/2020.12.24.20248821

29 December – studies 521 & 522 added.  Citation for study 313 updated.

Study 522 – Pancreatitis in a pregnant woman with Covid-19

A woman with severe Covid-19 at 33 weeks gestation also developed pancreatitis (click here or Acute_Pancreatitis_in_a_Pregnant_Patient_With.75). She went into preterm labour and delivered vaginally. Both mother and baby recovered. From author affiliations she was cared for at the Mayo Clinic, Rochester, Minnesota. USA, which has not previously reported cases. Citation: Narang K, Szymanski LM, Kane SV, Rose CH. Acute Pancreatitis in a Pregnant Patient With Coronavirus Disease 2019 (COVID-19). Obstet Gynecol. 2020 Dec 22;Publish Ahead of Print. doi: 10.1097/AOG.0000000000004287. Epub ahead of print. PMID: 33355431.

Study 521 – 57 cases from India

Between May 5, and June 5, 2020, 348 pregnant women were tested and 57 positive for SARS-CoV-2 at Safdarjung Hospital, New Delhi (click here or PIIS170121632030829X). Three women died. Five babies tested positive but survived. Two test negative babies died. Likely overlap with study 441. Citation: Sumitra Bachani, Renu Arora, Anjali Dabral, Sheeba Marwah, Pratima Anand, K. Sravani Reddy, Nitesh Gupta, Balwinder Singh, Clinical Profile, Viral Load, MaternalFetal Outcomes of Pregnancy With COVID-19: 4-Week Retrospective, Tertiary Care Single-Centre Descriptive Study J Obstet Gynaecol Can 2020;000(000):1−9. https://doi.org/10.1016/j.jogc.2020.09.021

24 December – study 520 added

Study 520 – 879 cases from India

This series from Nair Hospital, Mumbai included 879 women with Covid-19 seen between April 4 and  September 10, 2020 (click here or ijgo.13508). They likely overlap with cases reported in studies 225, 283, 369 and 501. Citation: Mahajan, N.N., Ansari, M., Gaikwad, C., Jadhav, P., Tirkey, D., Pophalkar, M.P., Bhurke, A.V., Modi, D.N., Mahale, S.D. and Gajbhiye, R.K. (2020), Impact of SARS‐CoV‐2 on multiple gestation pregnancy. Int J Gynecol Obstet. https://doi.org/10.1002/ijgo.13508

23 December – studies 518 and 519 added

Study 519 – 127 cases from USA

A detailed analysis of viraemia, and placental transfer of virus and antibodies, in 127 pregnant women with SARS-CoV-2 (click here or edlow_2020_oi_200960_1607964328.94511). They were cared for in Massachusetts General, Brigham and Women’s Hospital, and Beth Israel Deaconess Medical Center, in Boston, Massachusetts between April 2 & June 13, 2020, and likely overlap with those in studies 129, 142, 231 and 232. Citation: Edlow AG, Li JZ, Collier AY, et al. Assessment of Maternal and Neonatal SARS-CoV-2 Viral Load, Transplacental Antibody Transfer, and Placental Pathology in Pregnancies During the COVID-19 Pandemic. JAMA Netw Open. 2020;3(12):e2030455. doi:10.1001/jamanetworkopen.2020.30455

Study 518 – 7,028 cases from Mexico

7,028 pregnant with COVID-19  identified through the Mexican Public Health Network between February 1st and October 27th (click here or Martinez Portilla AJOG). 93 (1.3%) women died. They had been cared for 475 unnamed monitoring hospitals. A further analysis of the series reported in study 513, with additional cases. Citation: Martinez Portilla RJ, Smith ER, He S, Torres JT, Espino-Y-Sosa S, Solis-Paredes JM, Poon LC, Young pregnant women are also at an increased risk of mortality and severe illness due to COVID-19: Analysis of the Mexican National Surveillance Program, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2020.12.1197. [important]

22 December – study 517 added

Study 517 – 47 screen positives in US

Of 126 women screened on admission in labour to Elmhurst Hospital, between March 29 and April 22, 45 tested positive for SARS-CoV-2 (click here or pone.0238409). They likely overlap with those in studies 160 and 236. Citation: Maru S, Patil U, Carroll-Bennett R, Baum A, Bohn-Hemmerdinger T, Ditchik A, et al. (2020) Universal screening for SARS-CoV-2 infection among pregnant women at Elmhurst Hospital Center, Queens, New York. PLoS ONE 15(12): e0238409. https://doi.org/10.1371/journal. pone.0238409

19 December – studies 513 to 516 added

Study 516 – 22 cases from China

22 neonates born to women with Covid-19 and admitted to Tongji Hospital, Wuhan, from January 1 to April 1, 2020 (click here or 1-s2.0-S0924857920304805-main). These cases have likely been reported before. Citation: Zheng He, Yinian Fang, Qin Zuo, Xiaoxing Huang, Yongfang Lei, Xiuhua Ren, Dong Liu, Vertical transmission and kidney damage in newborns from coronavirus disease 2019 infection pregnant mother, International Journal of Antimicrobial Agents (2020), doi: https://doi.org/10.1016/j.ijantimicag.2020.106260

Study 515 – 90 cases from Iran

45 symptomatic and 45 asymptomoatic women with SARS-CoV-2 were compared (click here or Pregnancy outcomes among symptomatic and asymptomatic women infected with COVID 19 in the west of Iran a case control study). They were cared for in various hospitals of Hamadan Province, and therefore likely overlap with study 375Citation: Ensiyeh Jenabi , Saeid Bashirian , Salman Khazaei , Seyedeh Zahra Masoumi , Samereh Ghelichkhani , Firoozeh Goodarzi & Mohammad Mirzaei (2020): Pregnancy outcomes among symptomatic and asymptomatic women infected with COVID-19 in the west of Iran: a case-control study, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1861599

Study 514 – 9 cases from Iran

A woman with Covid-19 gave birth at 37 weeks (click here or aaem-9-e5). The baby tested positive. The babies of 8 other affected women in the same hospital tested negative. They were cared for at Mahdiyeh Hospital, Shahid Beheshti University of Medical Sciences, Tehran, which has not previously reported cases. Citation: Parsa Y, Shokri N, Jahedbozorgan T, Naeiji Z, Zadehmodares S, Moridi A. Possible Vertical Transmission of COVID-19 to the Newborn; a Case Report: Vertical Transmission and The Coronavirus . Arch Acad Emerg Med [Internet]. 2020Nov.15 [cited 2020Dec.19];9(1):e5. Available from: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/923

Study 513 – 5,183 cases in Mexico

5,183 pregnant women with Covid-19 identified throught the National Data Registry of Mexico from February 1st, to October 28th, 2020 (click here or uog.23575). 77 (1·5%) mothers died. They had been cared for in 475 unnamed monitoring hospitals, located in all 32 states. Citation: Martinez‐Portilla, R.J., Sotiriadis, A., Chatzakis, C., Torres‐Torres, J., Espino y Sosa, S., Sandoval‐Mandujano, K., Castro‐Bernabe, D.A., Medina‐Jimenez, V., Monarrez‐Martin, J.C., Figueras, F. and Poon, L.C. (2020), Pregnant women with SARS‐CoV‐2 infection are at higher risk of death and severe pneumonia: propensity score‐matched analysis of a nationwide prospective cohort study (COV19Mx). Ultrasound Obstet Gynecol. Accepted Author Manuscript. https://doi.org/10.1002/uog.23575

18 December – studies 511 (belatedly) and 512 added

Study 512 – 60 cases from Turkey

60 pregnant women with Covid-19 (click here or jmv.26725). Cared for in Ankara City Hospital between 26 June and 27 August 2020.  Probably overlapping with studies 31, 203, 223, 244, 399 & 444. Citation: Erol, S.A., Tanacan, A., Anuk, A.T., Tokalioglu, E.O., Biriken, D., Keskin, H.L., Tekin, O.M., Yazihan, N. and Sahin, D. (2020), Evaluation of Maternal Serum Afamin and Vitamin E Levels in Pregnant Women with COVID‐19 and Its Association with Composite Adverse Perinatal Outcomes. J Med Virol. Accepted Author Manuscript. https://doi.org/10.1002/jmv.26725

Study 511 – 9 cases from China

We were originally unable to source this early paper despite it being cited in a number of early reports (click here or 1007-9408-23-0004s). Patients were treated in the People’s Hospital of Wuhan University from January 22 to February 1, 2020, and therefore likely reported many times elsewhere. In Chinese. Citation: Lei Di, Wang Chen, Li Chunyan, et al. Clinical analysis of 9 cases of pregnancy with new coronavirus pneumonia[J]. Chinese Journal of Perinatal Medicine, 2020,23 (03): 225-231. DOI: 10.3760/cma. j.cn113903-20200216-00117

17 December – study 510 added

Study 510 – 1,584 cases in Canada

The first report of the Canadian Covid in pregnancy registry CanCovid (click here or CANCOVID-Preg-report-1-BC-AB-ON-data_02DEC2020).  As of November 23rd, 2020, 1,584 pregnant women with SARS-CoV-2 had been reported in Canada. 430 are reported here in detail. Eight were admitted to ITU. Nos. of events which affected <6 woman are not reported. Citation: Deborah Money. CANADIAN SURVEILLANCE OF COVID-19 IN PREGNANCY: EPIDEMIOLOGY, MATERNAL AND INFANT OUTCOMES Report #1: Released December 2nd, 2020 School of Population & Public Health, University of British Colombia [important]

15 December update – study 509 added

Study 509 – Case in China

A woman with Covid-19 at 36 weeks was delivered by Caesarean on 24 January (click here or PIIS0007091220301318). She was cared for at Wuhan Red Cross Hospital grid.507948.7, which has not previously reported cases. Citation: Xia H, Zhao S, Wu Z, Luo H, Zhou C, Chen X. Emergency Caesarean delivery in a patient with confirmed COVID-19 under spinal anaesthesia. Br J Anaesth. 2020 May;124(5):e216-e218. doi: 10.1016/j.bja.2020.02.016. Epub 2020 Mar 17. PMID: 32192711; PMCID: PMC7118662.

14 December update – studies 501 (HT Rahul Gajbhiye) to 508 added

Study 508 – Case in Iran

A woman with Covid-19 was delivered by Caesarean section at term and suffered a post-partum pulmonary embolus (click here or 20-1383). She was cared for [undated] at Shiraz University of Medical Sciences, Iran, which has not previously reported cases. Citation: Khodamoradi Z, Boogar SS, Shirazi FKH, Kouhi P. COVID-19 and Acute Pulmonary Embolism in Postpartum Patient. Emerg Infect Dis. 2020;26(8):1937-1939. doi:10.3201/eid2608.201383

Study 507 – 71 cases in USA

71 pregnant women with Covid-19 and their babies (click here or s-0040-1713416) were cared for [March 31, to May 5, 2020] in Morristown Medical Center, and at Overlook Medical Center, New Jersey, and therefore may overlap with those reported in study 159. Citation: Griffin I, Benarba F, Peters C, Oyelese Y, Murphy T, Contreras D, Gagliardo C, Nwaobasi-Iwuh E, DiPentima MC, Schenkman A. The Impact of COVID-19 Infection on Labor and Delivery, Newborn Nursery, and Neonatal Intensive Care Unit: Prospective Observational Data from a Single Hospital System. Am J Perinatol. 2020 Aug;37(10):1022-1030. doi: 10.1055/s-0040-1713416. Epub 2020 Jun 13. PMID: 32534458; PMCID: PMC7416206.

Study 506 – 37 cases in USA

37 pregnant women with Covid-19 were cared for at Flushing Hospital Medical Centre or Jamaica Hospital Medical Centre, New York, between March 20, and April 30, 2020 (click here or IDOG2020-8460672). Neither hospital has previously reported cases. Citation: Sindy C. Moreno, Justin To, Hajoon Chun, Ivan M. Ngai, “Vertical Transmission of COVID-19 to the Neonate”, Infectious Diseases in Obstetrics and Gynecology, vol. 2020, Article ID 8460672, 5 pages, 2020. https://doi.org/10.1155/2020/8460672

Study 505 – Case in USA

A woman with clinical Covid-19 (PCR negative but antibody positive) at 26 weeks gestation required 23 days ventilation (click here or CRIOG2020-8891787). She delivered vaginally at 39 weeks. The baby was healthy. From author affiliations she was cared for at Presbyterian-Brooklyn Methodist Hospital, New York, so may be included in study 230 and possibly other studies from the NY Presbyterian network. Citation: Farah Alsayyed, Victoria Hastings, Sanford Lederman, “Expectant Management of a Critically Ill Pregnant Patient with COVID-19 with Good Maternal and Neonatal Outcomes”, Case Reports in Obstetrics and Gynecology, vol. 2020, Article ID 8891787, 6 pages, 2020. https://doi.org/10.1155/2020/8891787

Study 504 – 4 mothers, 5 babies in Italy

Four women with Covid-19 had five babies who became infected (click here or olivini It J Ped 2020). From author affiliations the babies were cared for at Bambino Gesù Children’s Hospital, Rome. The paper has no OB authors so it is not clear which maternity hospital cared for the mothers. However, it is possible that some of them were included in studies 76, 78 and 464. Citation: Olivini, N., Calò Carducci, F.I., Santilli, V. et al. A neonatal cluster of novel coronavirus disease 2019: clinical management and considerations. Ital J Pediatr 46, 180 (2020). https://doi.org/10.1186/s13052-020-00947-9

Study 503 – “Rooming in” in Italy

Of 61 mothers with Covid-19, and 62 neonates “roomed in”, only one baby got infected (click here or jamapediatrics_ronchi_2020_oi_200078_1605627156.62602). They were cared for in at 6
COVID-19 maternity centers, located in Lombardy, Northern Italy, between March 19 & May 2, 2020, and therefore probably overlap with those reported in the other Lombardy series. Citation: Ronchi A, Pietrasanta C, Zavattoni M, et al. Evaluation of Rooming-in Practice for Neonates Born to Mothers With Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Italy. JAMA Pediatr. Published online December 07, 2020. doi:10.1001/jamapediatrics.2020.5086

Study 502 – ICNARC 2nd wave, UK

The UK Intensive Care National Audit & Research Centre (ICNARC) is now reporting patients with Covid on ICU separately for the periods before and after 1 September 2020 (click here or ICNARC_COVID-19_Report_2020-12-11), For the period after 1 September, 13 currently pregnant and 12 recently pregnant women with Covid-19, had been admitted to ITU, of whom 8 and 10 respectively had been ventilated.

Study 501 – Case in India

A woman contracted Covid-19 at 30 weeks and developed delirium (click here or 1-s2.0-S1876201820306262-main). She recovered but the baby died. Three cases of post partum psychosis in women with Covid from the same hospital are mentioned. The hospital is Nair Hospital, Mumbai, so these cases may be included in studies 225, 283 & 369. Citation: Mahajan NN, Gajbhiye RK, Pednekar RR, Pophalkar MP, Kesarwani SN, Bhurke AV, Mahale SD, Delirium in a pregnant woman with SARS-CoV-2 infection in India, Asian Journal of Psychiatry (2020), doi: https://doi.org/10.1016/j.ajp.2020.10251

13 December update – studies 499 and 500 added

Study 500 – 7 cases in China

Seven pregnant women with Covid-19 (click here or 12098_2020_Article_3372). They were cared for in 5 provincial hospitals inHubei, namely Renmin Hospital of Wuhan University (n = 2) grid.412632.0, Huangshi Maternal and Child Health Hospital (n = 2) does not disambiguate, Jingzhou Maternal and Child Health Hospital (n = 1) grid.507996.4, Jingmen First Renmin Hospital (n = 1) does not disambiguate, and Zaoyang First Renmin Hospital (n = 1) which does not disambiguate. It is likely that the various Renmin hospital cases have been reported elsewhere. The Jingzhou case may not have been reported before. Citation: Nawsherwan, Khan S, Nabi G, Fan C, Wang S. Impact of COVID-19 Pneumonia on Neonatal Birth Outcomes. Indian J Pediatr. 2020;87(8):645-646. doi:10.1007/s12098-020-03372-2

Study 499 – 19 cases in China

17 mothers with Covid-19 and their babies (click here or 11684_2020_Article_772). They were cared for in Tongji Hospital in Wuhan, and therefore likely included in many previous reports. Citation: Liu W, Wang J, Li W, Zhou Z, Liu S, Rong Z. Clinical characteristics of 19 neonates born to mothers with COVID-19. Front Med. 2020;14(2):193-198. doi:10.1007/s11684-020-0772-y

12 December update – studies 493 to 498 added

Study 498 – Case in China

A 30-year-old woman with Covid-19 at 35-weeks was delivered by caesarean and became depressed and anxious after her baby was isolated (click here or JZUSB21-0394). From author affiliations she was cared for at the First Affiliated Hospital, Zhejiang University School of Medicine, grid.452661.2, Hangzhou, and may therefore the same case as in studies 4 and 9. Citation: Huang JW, Zhou XY, Lu SJ, et al. Dialectical behavior therapy-based psychological intervention for woman in late pregnancy and early postpartum suffering from COVID-19: a case report. J Zhejiang Univ Sci B. 2020;21(5):394-399. doi:10.1631/jzus.B2010012

Study 497 – Case in China

A woman contracted Covid-19 at 36 weeks (click here or 540_2020_Article_2796). She delivered by Caesarean at 37 weeks. Both mother and baby recovered. From author affiliatons she was cared for at the Second Affiliated Hospital of Xi’an Jiaotong University, grid.452672.0 Xi’an, Shaanxi, which has not previously reported cases. Citation: Du Y, Wang L, Wu G, Lei X, Li W, Lv J. Anesthesia and protection in an emergency cesarean section for pregnant woman infected with a novel coronavirus: case report and literature review. J Anesth. 2020;34(4):613-618. doi:10.1007/s00540-020-02796-6

Study 496 – Case in USA

A woman contracted Covid-19 and vulvovaginitis at 31 weeks (click here or s-0040-1713665). From author affiliations she was treated at the Hospital of the University of Pennsylvania, Philadelphia, so might be included in studies 86, 175, 302 & 350. Citation: Rubin ES, Sansone SA, Hirshberg A, Clement EG, Srinivas SK. Detection of COVID-19 in a Vulvar Lesion. Am J Perinatol. 2020 Sep;37(11):1183-1184. doi: 10.1055/s-0040-1713665. Epub 2020 Jul 2. PMID: 32615620; PMCID: PMC7516389.

Study 495 – 17 self-reported cases in Belgium

17 out of 6,470 self-selected pregnant or breast feeding women completing an internet survey, reported testing positive for SARS-CoV-2 (click here or ijerph-17-06766 (1)). Citation: Ceulemans M, Verbakel JY, Van Calsteren K, Eerdekens A, Allegaert K, Foulon V. SARS-CoV-2 Infections and Impact of the COVID-19 Pandemic in Pregnancy and Breastfeeding: Results from an Observational Study in Primary Care in Belgium. Int J Environ Res Public Health. 2020 Sep 17;17(18):6766. doi: 10.3390/ijerph17186766. PMID: 32957434; PMCID: PMC7559009. 

Study 494 – Case from Umbria, Italy

A woman with Covid-19 at 32 weeks gestation (click here or Lettera – Indraccolo). The pregnancy outcome was not reported. She was cared for at “Alto Tevere”, Hospital of Città di Castello, which has not previously reported cases.  Citation: Indraccolo U. A pregnant woman and the SARS-CoV-2 infection: how are barriers easily crossed? Recenti Prog Med. 2020 Apr;111(4):259-260. doi: 10.1701/3347.33190. PMID: 32319449.

Study 493 – Patient treated with ECMO in China

One of four patients treated with convalescent plasma was pregnant (click here or PIIS0012369220305717). She was aged 31, 35 weeks gestion, delivered by caesarean and following treatment with ECMO recovered. The baby died. She was initially treated at Xiaolan People’s Hospital of Zhongshan, and later transferred to the Second People’s Hospital of Zhongshan, neither of which disambiguates on GRID.ac but which must be the same as Zhongshan People’s Hospital grid.476868.3. This appears to be the sixth report of this woman, (studies 3, 57, 81, 192 & 433Citation: Zhang B, Liu S, Tan T, Huang W, Dong Y, Chen L, Chen Q, Zhang L, Zhong Q, Zhang X, Zou Y, Zhang S. Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection. Chest. 2020 Jul;158(1):e9-e13. doi: 10.1016/j.chest.2020.03.039. Epub 2020 Mar 31. PMID: 32243945; PMCID: PMC7195335.

11th December update – studies 491 and 492 added

Study 492 – 4 cases in Jordan

Four pregnant women with mild Covid-19 (click here or ijgo.13240). They were cared for in the King Abdullah University Hospital, Irbid, so may overlap with cases in studies 153, 435 & 463. Citation: Alsharaydeh I, Rawashdeh H, Saadeh N, Obeidat B, Obeidat N. Challenges and solutions for maternity and gynecology services during the COVID-19 crisis in Jordan. Int J Gynaecol Obstet. 2020 Aug;150(2):159-162. doi: 10.1002/ijgo.13240. Epub 2020 Jun 17. PMID: 32470178.

Study 491 – Abortion case in New York

An asymptomatic woman with sickle cell disease undergoing abortion by D&E at 15 weeks developed post operative pneumonia and tested positive for SARS-CoV-2 (click here or PIIS0010782420301530). From author affiliations she was cared for at Columbia University Irving Medical Center, previous reports from which (studies 14, 27, 136, & 271) have not included pregnancy termination cases. Citation: Fang NZ, Castaño PM, Davis A. A hospital-based COVID-19 abortion case in the early phase of the pandemic. Contraception. 2020;102(2):137-138. doi:10.1016/j.contraception.2020.05.005

8th December update – studies 478 to 490 added

Study 490 – Case in USA

A woman with Covid-19 was delivered by Caesarean at 35 weeks (click here or acc-14-e01303). She was cared for at Boston Medical Center, Boston, Massachusetts, so might be included in study 292. Citation: Norris MC, Kalustian A, Salavati S. Epidural Blood Patch for Postdural Puncture Headache in a Patient With Coronavirus Disease 2019: A Case Report. A&A Practice. 2020 Aug;14(10):e01303. DOI: 10.1213/xaa.0000000000001303.

Study 489 – Case in China

A woman contracted Covid-19 at 35 weeks, and was delivered by Caesarean (click here or BMJ-37-226). She recovered. From author affiliations she was cared for at Chongqing Three Gorges Central Hospital, grid.477128.f Chongqing. Other features also suggest this and study 252 describe the same woman. Citation: Liao X, Yang H, Kong J, Yang H. Chest CT Findings in a Pregnant Patient with 2019 Novel Coronavirus Disease. Balkan Med J. 2020;37(4):226-228. doi:10.4274/balkanmedj.galenos.2020.2020.3.89

Study 488 – 20 cases detected by screening in USA

Four hospitals associated with Mass General Brigham Health, Massachusetts, tested 757 women admitted in labour between April 18th & May 5th. 20 were positive for SARS-CoV-2 (click here or S0899823X2000255Xa). This organisation has not previously reported cases. Citation: Goldfarb IT, Diouf K, Barth WH, et al. Universal SARS-CoV-2 testing on admission to the labor and delivery unit: Low prevalence among asymptomatic obstetric patients. Infect Control Hosp Epidemiol. 2020;41(9):1095-1096. doi:10.1017/ice.2020.255

Study 487 – 5 cases in USA

There were 79/1,811 SARS-CoV-2 positive tests between April 27, and May 18, in a big hospital. Five were in pregnant women (click here or S0899823X2000358Xa). The hospital is unnamed, but probably affiliated with Virginia Commonwealth University, Richmond, Virginia,. Citation: : Sastry SR, et al. (2020). Universal screening for the SARS-CoV-2 virus on hospital admission in an area with low COVID-19 prevalence. Infection Control & Hospital Epidemiology, https://doi.org/10.1017/ice.2020.358

Study 486 – 37 cases in Chile

37/583 pregnant women had a positive test for SARS CoV-2 (click here or journal.pone.0239887). Two women required ventilation. None died. Two babies tested positive. One baby, who tested negative, died. The study was conducted in Clınica Davila, Santiago, which has not previously reported cases. Citation: Dı´az-Corvillo´n P, Mo¨nckeberg M, Barros A, Illanes SE, Soldati A, Nien J-K, et al. (2020) Routine screening for SARS CoV-2 in unselected pregnant women at delivery. PLoS ONE 15(9): e0239887. https://doi.org/10.1371/journal.pone.0239887

Study 485 – 3 cases in Spain

Three pregnant women with Covid-19 (click here or main (9) In Spanish). From author affiliations cared for at Hospital Universitario Materno-Infantil de Jaén, Jaén, so may overlap with study 158. Citation: Hijona Elósegui JJ, Carballo García AL, Fernández Risquez AC. New evidences that discard the possible vertical transmission of SARS-CoV-2 during pregnancy. Nuevas evidencias que descartan la posible transmisión vertical del SARS-CoV-2 durante la gestación. Med Clin (Barc). 2020;155(7):313-314. doi:10.1016/j.medcli.2020.05.021

Study 484 – Case report in Italy

A pregnant woman with Covid-19 also had a pulmonary embolus (click here or PIIS0049384820301389). She was cared for in Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, so probably included in the Lombardy series. Citation: Martinelli I, Ferrazzi E, Ciavarella A, Erra R, Iurlaro E, Ossola M, Lombardi A, Blasi F, Mosca F, Peyvandi F. Pulmonary embolism in a young pregnant woman with COVID-19. Thromb Res. 2020 Jul;191:36-37. doi: 10.1016/j.thromres.2020.04.022. Epub 2020 Apr 20. PMID: 32371163; PMCID: PMC7169886.

Study 483 – 21 cases in Italy

21 women with Covid-19 during pregnancy (click here or R02Y2020N11A1248). From author affiliations cared for at Spedali civili of Brescia, Brescia, so likely included in the various Lombardy series. Citation: Giannini A, Mantovani A, Vezzoli C, Franchini D, Finazzi P. Lung ultrasound for pregnant women admitted to ICU for COVID-19 pneumonia. Minerva Anestesiol. 2020 Nov;86(11):1248-1249. doi: 10.23736/S0375-9393.20.14726-6. Epub 2020 May 29. PMID: 32486608.

Study 482 – Case in Iraq

A pregnant woman with Covid-19 at 28 weeks went into preterm labour and delivered at 30 weeks (click here or AsianPacJReprod000-415713_113251). The baby was not infected. From author affiliations she was cared for at Al-Kadhemia Teaching Hospital, Baghdad. This is the first report from Iraq. Citation: Al-Kuraishy, H., Al-Maiahy, T., Al-Gareeb, A., Musa, R., & Ali, Z. (2020). COVID-19 pneumonia in an Iraqi pregnant woman with preterm delivery. Asian Pacific Journal of Reproduction, 9(3). https://doi.org/10.4103/2305-0500.282984

Study 481 – Puerperal skin manifestations of Covid-19

A woman with Covid-19 developed a skin rash 7 days post partum (click here or ijd.14919). She was cared for at San Raffaele Hospital, Milan, Italy, so may have been included in the various Lombardy series. Citation: Paolino, G., Canti, V., Mercuri, S.R., Rovere Querini, P., Candiani, M. and Pasi, F. (2020), Diffuse cutaneous manifestation in a new mother with COVID‐19 (SARS‐Cov‐2). Int J Dermatol, 59: 874-875. https://doi.org/10.1111/ijd.14919

Study 480 – Puerperal case in USA

A woman with puerperal Covid-19 (click here or 10-1055-s-0040-1712926). From author affiliations she was cared for at University of Alabama at Birmingham, Alabama, which has not previously reported cases. Citation: Sinkey RG, Rajapreyar I, Robbins LS, et al. Heart Failure with Preserved Ejection Fraction in a Postpartum Patient with Superimposed Preeclampsia and COVID-19. AJP Rep. 2020;10(2):e165-e168. doi:10.1055/s-0040-1712926

Study 479 – Patient in the Netherlands

A pregnant woman with systemic lupus erythematosus, using long-term corticosteroids, contracted Covid-19 (click here or bcr-2020-235581). She gave birth normally and the baby was unaffected. She was cared for at Reinier de Graaf Gasthuis, Delft, which has not previously reported cases. Citation: Grimminck K, Santegoets LAM, Siemens FC, et al. BMJ Case Rep 2020;13:e235581. doi:10.1136/bcr-2020-235581

Study 478 – Case report from Caracas, Venezuela

A woman tested postive for SARS-CoV-2 during the pregnancy, and had mild symptoms, but had recovered by the time she was delivered by Caesarean on March 31st (click here or main (8)). The baby tested negative. The birth hospital is not named. Citation: Forero-Peña DA, Rodríguez MI, Flora-Noda DM, et al. The first pregnant woman with COVID-19 in Venezuela: Pre-symptomatic transmission. Travel Med Infect Dis. 2020;36:101805. doi:10.1016/j.tmaid.2020.101805

7th December – studies 464 to 475 added

Study 475 – 308 cases from Mexico

Using open data from the Mexican Ministry of Health up to May 17th, 7/308 pregnant women with Covid-19 had died (click here or ijgo.13250). This report will overlap with study 340. Citation: Lumbreras‐Marquez, M.I., Campos‐Zamora, M., Lizaola‐Diaz de Leon, H. and Farber, M.K. (2020), Maternal mortality from COVID‐19 in Mexico. Int J Gynecol Obstet, 150: 266-67. https://doi.org/10.1002/ijgo.13250

Study 474 – 12 cases from Turkey

No SARS-CoV-2 was detected in vaginal fluid of 12 pregnant women with COVID-19 (click here or SARS CoV 2 is not present in the vaginal fluid of pregnant women with COVID 19 (1)). All had mild symptoms and none needed critical care. From author affiliations they were cared for at Sakarya Training and Research Hospital, Sakarya, Turkey, which has not previously reported cases. Citation: Mehmet Musa Aslan , Hilal Uslu Yuvacı , Osman Köse , Hande Toptan , Nermin Akdemir , Mehmet Köroğlu , Arif Serhan Cevrioğlu & Selçuk Özden (2020): SARS-CoV-2 is not present in the vaginal fluid of pregnant women with COVID-19, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1793318

Study 473 – Thrombocytopaenia & mild Covid-19

Three pregnant wowen with mild Covid-19 also had thrombocytopaenia (click here or main (7)). From author affiliations they were cared for at Antoine-Beclere Hospital, Paris, so may overlap with studies 217 and 326. Citation: Le Gouez A, Vivanti AJ, Benhamou D, Desconclois C, Mercier FJ. Thrombocytopenia in pregnant patients with mild COVID-19. Int J Obstet Anesth. 2020;44:13-15. doi:10.1016/j.ijoa.2020.05.010

Study 472 – 16 cases from China

These 16 pregnant women with COVID‐19 up until February 16, 2020 in Wuhan Union Hospital (click here or ijgo.13236) have probably been reported before. Citation: Zeng Y, Lin L, Yan Q, Wei W, Xiang Yang B, Huang R, He F, Chen D. Update on clinical outcomes of women with COVID-19 during pregnancy. Int J Gynaecol Obstet. 2020 Aug;150(2):264-266. doi: 10.1002/ijgo.13236. Epub 2020 Jun 9. PMID: 32438521.

Study 471 – 12 cases from China

12 pregnant women with Covid-19 (click here or 1-s2.0-S0890623820302677-main). They were cared for at Renmin Hospital of Wuhan University grid.412632.0 and the near hospitals in Wuhan City, Hubei Province, China. They have therefore probably already been reported. Citation: Cuifang Fan, No obviously adverse pregnancy complications and outcomes of the recovered pregnant women from COVID-19. Letter. Reproductive Toxicology, https://doi.org/10.1016/j.reprotox.2020.11.008

Study 470 – Screening in Madrid, Spain

86 seropositive pregnant women were detected out of 759 tested between February 28th and May 10th (click here or pone.0243029). The hospital was Hospital Universitario 12 de Octubre, so they may overlap with those in studies 205 and 458. Citation: Villalaı´n C, Herraiz I, Luczkowiak J, Pe´rez-Rivilla A, Folgueira MD, Mejı´a I, et al. (2020) Seroprevalence analysis of SARS-CoV-2 in pregnant women along the first pandemic outbreak and perinatal outcome. PLoS ONE 15(11): e0243029. https://doi.org/10.1371/journal.pone.0243029

Study 469 – Case report from Turkey

An asymptomatic woman with SARS-CoV-2 delivered by Caesarean (click here or jog.14584). Cared for at Umraniye Training and Research Hospital Emergency Obstetrics Clinic, Istanbul, which has not previously reported cases. Citation: Palalioglu, R.M., Mahammadaliyeva, A., Erbiyik, H.I. and Muhcu, M. (2020), COVID‐19 in third trimester may not be as scary as you think, it can be innocent: Evaluating vertical transmission from a COVID‐19 positive asymptomatic pregnant woman with early membrane rupture. J. Obstet. Gynaecol. Res.. https://doi.org/10.1111/jog.14584

Study 468 – 4 patients from Canada

Four pregnant patients with SARS-CoV-2 were identified by screening (click here or birt.12520). It’s not possible to determine from author affiliations which centre in Toronto, cared for them, so some may have been included in studies 48 and 103. Citation: Mei-Dan, E, Satkunaratnam, A, Cahan, T, Leung, M, Katz, K, Aviram, A. Questionnaire‐based vs universal PCR testing for SARS‐CoV‐2 in women admitted for delivery. Birth. 2020; 00: 1– 8. https://doi.org/10.1111/birt.12520

Study 467 – 137 cases from West French Guiana

Of 137 pregnant women with SARS-CoV-2 infection, 3 required ITU admission but none died (click here or hcini ejog). There were 3 terminations and 7 stillbirths. Four babies were infected. Patients were cared for at West French Guiana Hospital Center (Centre Hospitalier de l’Ouest Guyanais), which has not previously reported cases. Citation: Hcini N, Maamri F, Picone O, Carod J-Francois, Lambert V, Mathieu M, Carles G, Pomar L, Maternal, fetal and neonatal outcomes of large series of SARS-CoV-2 positive pregnancies in peripartum period: a single-center prospective comparative study, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.11.068

Study 466 – Case report from USA

A woman with Covid-19 required ventilation (click here or Coronavirus_Disease_2019__COVID_19__Related.74). She survived. From author affiliations she was cared for in North Shore University Hospital, Manhasset, New York, which means she might be included in study 179. Citation: Gulersen, Moti MD, MSc; Staszewski, Cara MD; Grayver, Evelina MD; Tam Tam, Hima MD; Gottesman, Eric MD; Isseroff, Donnie MD; Rochelson, Burton MD; Bonanno, Clarissa MD Coronavirus Disease 2019 (COVID-19)–Related Multisystem Inflammatory Syndrome in a Pregnant Woman, Obstetrics & Gynecology: December 3, 2020 – Volume Latest Articles – Issue – 10.1097/AOG.0000000000004256 doi: 10.1097/AOG.0000000000004256 

Study 465 – Case report from China

A woman with Covid-19 at 34 weeks cared for at Renmin Hospital of Wuhan University (click here or ijgo.13232). Probably included in a multiple previous studies. Citation: Yu, Y., Fan, C., Bian, J. and YinShen, (2020), Severe COVID‐19 in a pregnant patient admitted to hospital in Wuhan. Int J Gynecol Obstet, 150: 262-263. https://doi.org/10.1002/ijgo.13232

Study 464 – Lung ultrasound in 4 cases

Four women with Covid-19 underwent lung ultrasound (click here or uog.22055). From author affiliations they were cared for at Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy, and may overlap with those in studies 76 and 78. Citation: Buonsenso, D., Raffaelli, F., Tamburrini, E., Biasucci, D.G., Salvi, S., Smargiassi, A., Inchingolo, R., Scambia, G., Lanzone, A., Testa, A.C. and Moro, F. (2020), Clinical role of lung ultrasound for diagnosis and monitoring of COVID‐19 pneumonia in pregnant women. Ultrasound Obstet Gynecol, 56: 106-109. https://doi.org/10.1002/uog.22055

6th December – studies 452 to 463 added

Study 463 – Case report from Jordan

A woman with Covid-19 (click here or 925512) was treated at King Abdullah University Hospital Irbid, Jordan, on March 28, 2020. She may therefore have been reported in studies 153 and 435. Citation: Bani Hani D.A. et al.: Successful anesthetic management in cesarean section for Pregnant Woman with COVID-19. Am J Case Rep, 2020; 21: e925512

Study 462 – Normal birth in Italy

A woman tested positive at 40 weeks gestation (click here or mjhid-12-1-e2020033). She gave birth normally. The baby tested negative. From author affiliations she gave birth at Santa Maria della Misericordia Hospital, Perugia, which has not previously reported cases. Citation: De Socio G.V., Malincarne L., Arena S., Troiani S., Benedetti S., Camilloni B., Epicoco G., Mencacci A., Francisci D. Delivery in asymptomatic italian woman with SARS-CoV-2 infection. Mediterr J Hematol Infect Dis 2020, 12(1): e2020033, DOI: http://dx.doi.org/10.4084/MJHID.2020.033&nbsp;

Study 461 – Maternal death in Iran

A woman contracted Covid-19 at 23 weeks with twins (click here or 29688-Article Text-117866-1-10-20200408). She died with the twins undelivered. She was cared for at Imam Hossein
Medical and Educational Center, Shahid Beheshti University of Medical Sciences, Tehran, which has not previously reported cases. Citation: Shojaei S, Kouchek M, Miri MM, Salarian S, Sistanizad M, Ariana S, et al. Twin pregnant woman with COVID-19: a case report. J Cell Mol Anesth. 2020;5(1):43-6

Study 460 – Severe case from Italy

A woman with Covid-19 at 27 weeks required 15 days ventilation (click here or sv-YX051401). She recovered and the baby remained undelivered. She was cared for in Azienda Ospedaliera Santa Croce e Carle, Cuneo, which has not previously reported cases. Citation: Luigi Barile, Martina Cerrano, Alessandro Locatelli, Andrea Puppo, Anna F. Signorile, Nicoletta Barzaghi. Prone Ventilation in a 27 Week Pregnant Woman with COVID-19 Severe ARDS. Signa Vitae. 2020. 16(1);199-202.

Study 459 – 6 cases from China

6 pregnant women with Covid-19 (click here or PIIS0163445320302929). Three required ITU admission and ventilation, and one ECMO. They all survived. The patients were cared for in the First Affiliated Hospital of Jinan University grid.412601.0, Guangzhou, Guangdong. This suggests possible overlap with studies 3, 57 and 81, all of which also reported a pregnant woman treated with ECMO. Citation: Huang, Wenhui et al. Unfavorable outcomes in pregnant patients with COVID-19.Journal of Infection, Volume 81, Issue 2, e99 – e101

Study 458 – 2 cases from Spain

2/203 women screened on admission in labour at Hospital Universitario 12 de Octubre in Madrid, tested positive (click here or [16193997 – Journal of Perinatal Medicine] Universal screening for SARS-CoV-2 before labor admission during Covid-19 pandemic in Madrid). Citation: Herraiz, I., Folgueira, D., Villalaín, C., Forcén, L., Delgado, R., & Galindo, A. (2020). Universal screening for SARS-CoV-2 before labor admission during Covid-19 pandemic in Madrid, Journal of Perinatal Medicine, 48(9), 981-984. doi: https://doi.org/10.1515/jpm-2020-0236

Study 457 – 94 cases in USA

94 confirmed or suspected cases of Covid-19 in pregnancy (click here or s-0040-1712529). From author affiliations they were cared for at Icahn School of Medicine at Mount Sinai, so overlap with studies 86, 119, 131 and 455 is likely. Citation: Fox NS, Melka S. COVID-19 in Pregnant Women: Case Series from One Large New York City Obstetrical Practice. Am J Perinatol. 2020 Aug;37(10):1002-1004. doi: 10.1055/s-0040-1712529. Epub 2020 May 21. PMID: 32438425; PMCID: PMC7416214.

Study 456 – 9 cases from Senegal

Nine pregnant women with Covid-19 from March 2 to May 15, were identified (click here or 58). They all recovered. This is the first report from Senegal. Citation: Abdoul Aziz Diouf et al. Clinical characteristics and outcomes of COVID-19 infection in nine pregnant women: a report from a sub-Saharan African country, Senegal. Pan African Medical Journal. 2020;35(2):58. [doi: 10.11604/pamj.supp.2020.35.2.23736]

Study 455 – Case report from USA

A woman with Covid-19 at 30 weeks improved after Caesarean delivery (click here or e236290.full). From author affiliations she was cared for at Icahn School of Medicine at Mount Sinai, New York, so she might be included in studies 86, 119, and 131. Citation: Oliva M, Hsu K, Alsamarai S, et al. Clinical improvement of severe COVID-19 pneumonia in a pregnant patient after caesarean delivery. BMJ Case Reports CP 2020;13:e236290.

Study 454 – Follow up of four patients in Study 6

The four women who were undelivered at the time of reporting study 6 recovered, but their pregnancy outocmes are still not reported (Click here or ajr.20.23247). Citation: Lin Li, Dehan Liu, and Lian Yang. Follow-Up Information About the Four Pregnant Patients With Coronavirus Disease (COVID-19) Pneumonia Who Were Still in the Hospital at the End of Our Study. American Journal of Roentgenology 2020 215:1, W17-W18

Study 453 – Lung ultrasound in 2 pregnant women with Covid-19, Spain

The lung ultrasound appearances of two pregnant women with Covid-19 (click here or jum.15419). From author affiliations they were cared for in Hospital General Universitario de Alicante, which has not previously reported cases. Citation: Gil‐Rodrigo, A., Llorens‐Soriano, P. and Ramos‐Rincón, J.‐M. (2020), Ultrasound in Pregnant Women With Suspected COVID‐19 Infection. J Ultrasound Med. https://doi.org/10.1002/jum.15419

Study 452 – Maternal death in Turkey

A woman with Covid-19 at 31 weeks gestation died (click here or 202587-454095-1-PB). The baby, born by Caesarean also died. From author affiliations they were cared for in University Kocaeli Derince Training and Research Hospital, Kocaeli. The case may have been included in studies 244 and 382. Citation: K. Uzel, I. V. Lakhno A MORTAL CASE OF CORONAVIRUS DISEASE IN A PREGNANT DIABETIC WOMAN. CLINICAL CASE Reproductive Endocrinology, ISSN: 2411-1295, Vol: 0, Issue: 52, Page: 33-36

5th December – studies 438 to 451 added

Study 451 – 24 cases, 3 severe, from UK

Of 24 pregnant or immediately post-partum patients with COVID-19, three required prolonged admittion to ICU (click here or 1751143720947547). They were cared for at Chelsea and Westminster NHS Foundation Trust in London, which has not previously reported cases. However they were probably included in study 92. The three ICU cases were probabaly incuded in the various ICNARC reports. Citation: Morton S, Lamont H, Silvey N, et al. Adult intensive care unit admissions with severe COVID-19 infection following emergency Caesarean section deliveries: A case series. Journal of the Intensive Care Society. August 2020. doi:10.1177/1751143720947547

Study 450 – Case report from China

This woman with Covid-19 who delivered in Maternal and Child Health Hospital of Hubei Province on April 5, 2020 (click here or medi-99-e21335) must have been included in many of the Wuhan series.. Citation: Peng J, Li R, Yin H, et al. A case report of a pregnant woman infected with coronavirus disease 2019 pneumonia. Medicine (Baltimore). 2020;99(30):e21335. doi:10.1097/MD.0000000000021335

Study 449 – 11 cases from Israel

11 pregnant women with SARS-CoV-2 infection cared for at Sheba Medical Center, Tel-Hashomer, Ramat Gan, (click here or Mohr-Sasson2020_Article_LaboratoryCharacteristicsOfPre). They may overlap with cases in studies 278 and 330. Citation: Mohr-Sasson A, Chayo J, Bart Y, Meyer R, Sivan E, Mazaki-Tovi S, Yinon Y. Laboratory characteristics of pregnant compared to non-pregnant women infected with SARS-CoV-2. Arch Gynecol Obstet. 2020 Sep;302(3):629-634. doi: 10.1007/s00404-020-05655-7. Epub 2020 Jun 22. PMID: 32572616; PMCID: PMC7307945.

Study 448 – a case with polymorphic eruption of pregnancy

A woman who tested positive for SARS-CoV-2 at 39 weeks developed polymorphic eruption of pregnancy 10 days after giving birth (click here or dth.14117). The hospital is not named but from author affiliations is affiliated with Sapienza University of Rome, Italy. Citation: Proietti I, Bernardini N, Tolino E, Mambrin A, Balduzzi V, Marchesiello A, Michelini S, Skroza N, Potenza C. Polymorphic eruption of pregnancy as a possible COVID-19 manifestation. Dermatol Ther. 2020 Aug 1:e14117. doi: 10.1111/dth.14117. Epub ahead of print. PMID: 32737915; PMCID: PMC7436318.

Study 447 – 29 cases from China

29 women with Covid-19 delivered 30 babies (one set of twins) between January 30 and March 10 (click here or journal.pmed.1003195 (1)). They were cared for in Renmin Hospital, Wuhan University, grid.412793.a and Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology grid.412793.a. They likely overlap with many previous reports from Wuhan. Citation: Wu YT, Liu J, Xu JJ, Chen YF, Yang W, Chen Y, Li C, Wang Y, Liu H, Zhang C, Jiang L, Qian ZX, Kawai A, Mol BW, Dennis CL, Xiong GP, Cheng BH, Yang J, Huang HF. Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China. PLoS Med. 2020 Jul 28;17(7):e1003195. doi: 10.1371/journal.pmed.1003195. PMID: 32722722; PMCID: PMC7386573.

Study 446 – A woman treated with ECMO in UK

A woman with severe Covid-19 was delivered by Caesarean at 39 weeks and required ventilation and ECMO (click here or demirjian2020). The baby tested positive and had clinical disease. Both eventually recovered. The birth took place at North Middlesex University Hospital NHS Trust, London, so although not cited, this is also case 1 in study 93. Citation: Demirjian A, Singh C, Tebruegge M, Herbert R, Draz N, Mirfenderesky M, Jones V, Hinstridge P, Seneviratne R, Myers R, Ellis J, Miah S, Meadows CI, Kenny J, Alonso A, Handforth J, Perkins S, Butler M, Blackburn F, Douthwaite S, Pillay D, Chand M, Zambon M. Probable Vertical Transmission of SARS-CoV-2 Infection. Pediatr Infect Dis J. 2020 Sep;39(9):e257-e260. doi: 10.1097/INF.0000000000002821. PMID: 32658096.

Study 445 – Miscarriage in Pakistan

A woman with Covid-19 miscarried at 11 weeks (click here or PIIS0163445320305879). She recovered. It is not possible to deduce which hospital cared for her from author affiliations. However, this is the first report from Islamabad. Citation: Rana MS, Usman M, Alam MM, Khalid A, Ikram A, Salman M, Zaidi SSZ, Faryal R, Qadir M, Umair M, Roohullah, Sufian MM. First trimester miscarriage in a pregnant woman infected with COVID-19 in Pakistan. J Infect. 2020 Sep 5:S0163-4453(20)30587-9. doi: 10.1016/j.jinf.2020.09.002. Epub ahead of print. PMID: 32896525.

Study 444 – SARS-CoV-2 detected in breast milk

A breast milk sample from an asymptomatic woman who tested positive for SARS-CoV-2 at birth, also tested positive (click here or 10.1089@bfm.2020.0161). The neonate tested negative and remained well. She was cared for Ankara City Hospital, Ankara, Turkey. The case may have been included in studies 95, 203 and 244. Citation: Bastug A, Hanifehnezhad A, Tayman C, Ozkul A, Ozbay O, Kazancioglu S, Bodur H. Virolactia in an Asymptomatic Mother with COVID-19. Breastfeed Med. 2020 Aug;15(8):488-491. doi: 10.1089/bfm.2020.0161. Epub 2020 Jul 1. PMID: 32614251.

Study 443 – No SARS-CoV-2 detected in colostrum

Seven women with SARS-CoV-2 positive tests at delivery gave samples of colostrum, which all tested negative (click here or bfm.2020.0183). From author affiliations the hospital was Puerta de Hierro-Majadahonda University Hospital, Madrid, Spain, so they likely overlap with cases in studies 125, 151, 177, and 196. Citation: Marín Gabriel MÁ, Malalana Martínez AM, Marín Martínez ME, Anel Pedroche J. Negative Transmission of SARS-CoV-2 to Hand-Expressed Colostrum from SARS-CoV-2-Positive Mothers. Breastfeed Med. 2020 Aug;15(8):492-494. doi: 10.1089/bfm.2020.0183. Epub 2020 Jul 9. PMID: 32644841.

Study 442 – 30 cases from China

30 pregnant women with Covid-19 treated in th Central Hospital of Wuhan grid.440160.7, China, from December 8, 2019 to April 1, 2020 are reported (click here or ijgo.13265). They overlap with those in study 39 and many other Wuhan series. Citation: Wang Z, Wang Z, Xiong G. Clinical characteristics and laboratory results of pregnant women with COVID-19 in Wuhan, China. Int J Gynaecol Obstet. 2020 Sep;150(3):312-317. doi: 10.1002/ijgo.13265. Epub 2020 Jul 3. PMID: 32510581; PMCID: PMC7496890.

Study 441 – 69 cases from India

69 women with SARS-CoV-2 had one abortion and four stillbirths (click here or Anand2020_Article_ClinicalProfileViralLoadManage). Of 65 live births, 7 neonates tested positive. There were two neonatal deaths both of whom tested negative. Two mothers died. From author affiliations they were cared for at Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, which has not previously reported cases. Citation: Anand P, Yadav A, Debata P, Bachani S, Gupta N, Gera R. Clinical profile, viral load, management and outcome of neonates born to COVID 19 positive mothers: a tertiary care centre experience from India. Eur J Pediatr. 2020 Sep 10:1–13. doi: 10.1007/s00431-020-03800-7. Epub ahead of print. PMID: 32910210; PMCID: PMC7482055.

Study 440 – Mother and obstetrician deaths in Nigeria

This predominantly opinion piece mentions a mother who died of Covid-19 in Lagos State University Teaching Hospital, who has not been reported elsewhere (click here or ijgo.13325). The article also refers to a newspaper report of an obstetrician who died of Covid-19 having been infected in his private clinic (added as report 274 here). Citation: Ijarotimi OA, Ubom AE, Olofinbiyi BA, Kuye-Kuku T, Orji EO, Ikimalo JI. COVID-19 and obstetric practice: A critical review of the Nigerian situation. Int J Gynaecol Obstet. 2020 Jul 22. doi: 10.1002/ijgo.13325. Epub ahead of print. PMID: 32698245.

Study 439 – One case from China

One pregnant woman in this series (click here or ijmsv17p2187). No further details. Hunan province is adjacent to Hubei province which contains the City of Wuhan. The authors are affiliated with hospitals in Changsha, Chenzhou, Loudi and Yiyang, all cities in Hunan. No previous cases have been reported from this province. Citation: Tao PY, Leng L, Liu K, Zhou RH, Hu YC, Wu SJ, Xiao YD, Liu J. Determination of risk factors for predicting the onset of symptoms in asymptomatic COVID-19 infected patients. Int J Med Sci. 2020 Aug 6;17(14):2187-2193. doi: 10.7150/ijms.47576. PMID: 32922180; PMCID: PMC7484673.

Study 438 – Maternal death in Turkey

A 22 year old woman died from Covid-19 at 32 weeks (click here or 42399_2020_Article_508). The baby, delivered by Caesarean, tested negative and survived. The mother had been treated with extra-corporal cytokine hemoadsorption therapy to remove inflammatory cytokines from the circulation. From author affliations she was cared for in Uşak Training and Research Hospital, Uşak,  which has not previously reported cases. Citation: Karabulut Keklik ES, Dal H, Bozok Ş. Cytokine Hemoadsorption in the Management of a Pregnant Woman with COVID-19 Pneumonia: Case Report [published online ahead of print, 2020 Sep 16]. SN Compr Clin Med. 2020;1-5. doi:10.1007/s42399-020-00508-5

4th December – studies 434 to 437 added

Study 437 – Case report from USA

A woman with Covid-19 at 34 weeks was delivered by emergency Caesarean for an abnormal CTG trace (click here or e625.full). The baby tested negative. From author affiliations the hospital was part of the NorthShore University Health System, Evanston, Illinois, which has not previously reported cases. Citation: Suresh SC, MacGregor CA, Ouyang DW. Urgent Cesarean Delivery Following Nonstress Test in a Patient with COVID-19 and Pregestational Diabetes. Neoreviews. 2020 Sep;21(9):e625-e630. doi: 10.1542/neo.21-9-e625. PMID: 32873658.

Study 436 – Case report from Korea

On March 6, 2020, a 28-year old woman with Covid-19 gave birth to a girl by Caesarean in Daegu Fatima Hospital at 37 weeks (click here or cep-2020-00850). This is probably the same patient as reported in study 22. Citation: Lee EK, Kim WD, Lee DW, Lee SA. Management of the first newborn delivered by a mother with COVID-19 in South Korea. Clin Exp Pediatr. 2020;63(9):373-375. doi:10.3345/cep.2020.00850

Study 435 – 2 patients delivered in a burns unit in Jordan

Two women with mild Covid-19 (but no burns) were delivered by caesarean section in a burns facility (click here or Altal2020_Article_PreparingTheBurnsUnitToAccommo). Neither baby was infected. All recovered. The hospital was King Abdullah University Hospital in Irbid, which may also be where the patient in study 153 delivered. The clinical features suggest that one of these cases is also that case.  Citation: Altal O, Bani Hani D, Aleshawi A, Alhowary AA, Obeidat B, Bani-Ata M. Preparing the Burns Unit to Accommodate Vaginal Delivery and Cesarean Section for Pregnant Women with COVID-19: A Successful Experience from Jordan. Adv Ther. 2020 Oct;37(10):4049-4053. doi: 10.1007/s12325-020-01457-0. Epub 2020 Aug 27. PMID: 32852673; PMCID: PMC7450677.

Study 434 – 242 women and 248 babies from Spain

This series from the Spanish Neo-COVID-19 Research Group seems to describe the same patients as those reported in study 390 (click here or Maternal,_Perinatal_and_Neonatal_Outcomes_With.2). There is also probably overlap with those in study 264b. Citation: Marín Gabriel MA, Reyne Vergeli M, Caserío Carbonero S, Sole L, Carrizosa Molina T, Rivero Calle I, Cuadrado Pérez I, Álvarez Fernández B, Forti Buratti A, Fernández-Cañadas Morillo A; Neo-COVID-19 Research Group. Maternal, Perinatal and Neonatal Outcomes With COVID-19: A Multicenter Study of 242 Pregnancies and Their 248 Infant Newborns During Their First Month of Life. Pediatr Infect Dis J. 2020 Dec;39(12):e393-e397. doi: 10.1097/INF.0000000000002902. PMID: 32947599.

3rd December – studies 428 to 433 added

Study 433 – pregnant woman with Covid-19 recovering after ECMO, China

A woman with Covid-19 at 35 weeks was ventilated, delivered by Caesarean, and treated with ECMO (click here or PIIS0147956320303599). She survived. The baby outcome is not reported in the present paper. She was cared for in Zhongshan People’s Hospital grid.476868.3, Zhongshan. It seems likely that this is the same case as reported in studies 3, 57, 81 and 192. In those papers the baby is reported to have died. The present paper cites none of those papers. Citation: Hou, Liusheng et al. First successful treatment of a COVID-19 pregnant woman with severe ARDS by combining early mechanical ventilation and ECMO. Heart & Lung: The Journal of Cardiopulmonary and Acute Care, Volume 0, Issue 0 https://doi.org/10.1016/j.hrtlng.2020.08.015 0147-9563

Study 432 – case report from Pakistan

A woman with Covid-19 was delivered by Caesarean (click here or JPAM_Vol_14_Issue2_p_1121-1123 (1)). The baby tested negative. Both recovered. She was cared for in Aziz Bhatti Shaheed Teaching Hospital in Gujrat, which has not previously reported cases. Citation: Tarar SH, Atta H, Khalid M, et al. A Case Report of Pregnant Lady having COVID-19 Delivered via Cesarean Section in Tertiary Care Hospital in Pakistan. J Pure Appl Microbiol. 2020;14(2):1121-1123. doi: 10.22207/JPAM.14.2.06

Study 431 – Case report from India

An asymptomatic woman who tested positive for SARS-CoV-2 was delivered by Caesarean at 38 weeks (click here or fmaa048). The asymptomatic baby was isolated and artificially fed, but tested positive at 48 hours. From author affiliations the hospital was S.N. Children Hospital, Prayagraj, Uttar Pradesh, which has not previously reported cases. Citation: Singh MV, Shrivastava A, Maurya M, Tripathi A, Sachan R, Siddiqui SA. Vertical Transmission of SARS-CoV-2 from an Asymptomatic Pregnant Woman in India. J Trop Pediatr. 2020 Sep 25:fmaa048. doi: 10.1093/tropej/fmaa048. Epub ahead of print. PMID: 32974677.

Study 430 – Screening in Italy

Of 333 pregnant women screened in four hospitals in Genoa, from April 1 to April 30, only one symptomatic patient (0.3%) and six asymptomatic ones (1.8%) tested positive (click here or JMV-9999-na). The hospitals were San Martino, G. Gaslini, Galliera and Villa Scassi – ASL3 Hospital, none of which have previously reported cases. Citation: Massarotti C, Adriano M, Cagnacci A, et al. Asymptomatic SARS-CoV-2 infections in pregnant patients in an Italian city during the complete lockdown [published online ahead of print, 2020 Aug 25]. J Med Virol. 2020;10.1002/jmv.26458. doi:10.1002/jmv.26458

Study 429 – Ovarian vein thrombosis and COVID‑19

A 26-year-old woman with Covid-19 at 8 weeks gestation also developed a right ovarian vein thrombosis  (click here or Mohammadi2020_Article_OvarianVeinThrombosisAfterCoro). The pregnancy outcome was not reported. She was cared for at Besat Hospital in Sanandaj, Iran, which has not previously reported cases. Citation: Mohammadi S, Abouzaripour M, Hesam Shariati N, Hesam Shariati MB. Ovarian vein thrombosis after coronavirus disease (COVID-19) infection in a pregnant woman: case report. J Thromb Thrombolysis. 2020 Oct;50(3):604-607. doi: 10.1007/s11239-020-02177-6. PMID: 32514763; PMCID: PMC7278233. 

Study 428 – Postnatal case from Italy

A 34-year-old pregnant woman gave birth on 9 August at the “Mater Dei” hospital, Bari, Apulia region, which has not previously reported cases (click here or main (6)). Both mother and baby contracted Covid-19 postnatally. Citation: Lenoci G, Galante D, Ceci E, et al. Sars-CoV-2 isolation from a 10-day-old newborn in Italy: A case report. IDCases. 2020;22:e00960. doi:10.1016/j.idcr.2020.e00960

2nd December – studies 419 to 427 added

Study 427 – 5 placentas from SARS-CoV-2 pregnancies

Five placentas from pregnancies positive for SARS-CoV-2 are described (click here or 511324). From author affiliations the pregnancies had been cared for at University Hospital Basel, Basel, Switzerland, which has not previously reported cases. Citation: Menter T, Mertz KD, Jiang S, Chen H, Monod C, Tzankov A, Waldvogel S, Schulzke SM, Hösli I, Bruder E. Placental Pathology Findings during and after SARS-CoV-2 Infection: Features of Villitis and Malperfusion. Pathobiology. 2020 Sep 18:1-9. doi: 10.1159/000511324. Epub ahead of print. PMID: 32950981; PMCID: PMC7573905.

Study 426 – Pregnancy, Covid-19 & sickle cell disease in Brazil

A pregnant woman with sickle cell disease contracted Covid-19 at 28 weeks gestation (click here or 2531-1379-htct-42-03-0212). She recovered and the pregnancy is ongoing. From author affiliations she was cared for in Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, which has not previously reported cases. Citation: JUSTINO, Caio Cesar et al. COVID-19 as a trigger of acute chest syndrome in a pregnant woman with sickle cell anemia. Hematol., Transfus. Cell Ther. [online]. 2020, vol.42, n.3 [cited 2020-12-02], pp.212-214. Available from: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2531-13792020000300212&lng=en&nrm=iso&gt;. Epub Sep 18, 2020. ISSN 2531-1387. https://doi.org/10.1016/j.htct.2020.06.003.

Study 425 – Pregnant health care workers with Covid in Mexico

Of 11,226 health-care workers with Covid-19 living in Mexico city, 38 (0.34%) were pregnant, compared with 49/23,869 (0.21%) of HCWs without Covid-19 (click here or ciaa1487). Citation: Antonio-Villa NE, Bello-Chavolla OY, Vargas-Vázquez A, Fermín-Martínez CA, Márquez-Salinas A, Bahena-López JP. Health-care workers with COVID-19 living in Mexico City: clinical characterization and related outcomes. Clin Infect Dis. 2020 Sep 28:ciaa1487. doi: 10.1093/cid/ciaa1487. Epub ahead of print. PMID: 32986819; PMCID: PMC7543362.

Study 424 – Screening in Belgium

Of 221 pregnant women tested on admission to the obstetric ward, 10 (4.5%) were positive, of whom 4 had symptoms (click here or [16193997 – Journal of Perinatal Medicine] Testing of patients and coronavirus disease 2019 (COVID-19) infection before scheduled deliveries (1)). The hospital was Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium. The cases may therefore overlap with those in studies 100 and 278, but likely not with those in studies 193 and 217. Citation: Yombi JC, De Greef J, Bernard P, Belkhir L. Testing of patients and coronavirus disease 2019 (COVID-19) infection before scheduled deliveries. J Perinat Med. 2020 Nov 26;48(9):995-996. doi: 10.1515/jpm-2020-0444. PMID: 32990649.

Study 423 – 111 cases from Wuhan, China

31 pregnant women admitted to Renmin Hospital of Wuhan University grid.412632.0 from January 15 to February 23 were compared with 80 non-pregnant women (click here or ofaa294). The cases may overlap with those in studies 6a, 10, 12, 36, 37, 40, 80, 183, 220 and 294. Citation: Biheng Cheng, Tao Jiang, Lu Zhang, Ruheng Hu, Jinhua Tian, Yan Jiang, Bo Huang, Jun Li, Min Wei, Jing Yang, Shengxiang Ren, Gaohua Wang, Clinical Characteristics of Pregnant Women With Coronavirus Disease 2019 in Wuhan, China, Open Forum Infectious Diseases, Volume 7, Issue 8, August 2020, ofaa294, https://doi.org/10.1093/ofid/ofaa294

Study 422 – Two mid-trimester cases from Wuhan, China

Two women contracted Covid-19 in the mid-trimester (click here or No evidence for vertical transmission of SARS CoV 2 in two neonates with mothers infected in the second trimester). The babies were unaffected. They were cared for in Wuhan No.1 Hospital grid.410609.a which appears to be separate from other Wuhan hospitals which have reported cases. Citation: Jing-yi Tang, Wen-qi Song, Hao Xu & Na Wang (2020) No evidence for vertical transmission of SARS-CoV-2 in two neonates with mothers infected in the second trimester, Infectious Diseases, 52:12, 913-916, DOI: 10.1080/23744235.2020.1798499

Study 421 – case report from Lima, Peru

An asymptomatic pregnant woman with SARS-CoV-2 antibodies, but PCR negative, delivered vaginally (click here or en_2304-5132-rgo-66-02-00008). From author affiliations the hospital was Delgado Clinic – AUNA, Lima, Peru, which has not previously reported cases.  Citation: Campodónico Olcese L, Paredes Salas JR, Campodónico Olcese D, Chang Vargas C, Acuña Barrueto L, Marchena Arias J. Management of eutocic delivery in a patient with COVID-19 in Lima, Peru. Rev Peru Ginecol Obstet: 2020;66(2) DOI: https://doi.org/10.31403/rpgo.v66i2251

Study 420 – 65 cases in Colombia

Of 946 pregnant women surveyed, between April 13 and May 18, in seven cities in Colombia, 65 had symptoms of Covid-19, 10 had required hospitalisation and 5 had tested positive. (click here or ijgo.13348). Citation: Parra‐Saavedra, M., Villa‐Villa, I., Pérez‐Olivo, J., Guzman‐Polania, L., Galvis‐Centurion, P., Cumplido‐Romero, Á., Santacruz‐Vargas, D., Rivera‐Moreno, E., Molina‐Giraldo, S., Guillen‐Burgos, H., Navarro, E., Flórez‐Lozano, K., Barrero‐Ortega, A., Sanz‐Cortes, M. and Miranda, J. (2020), Attitudes and collateral psychological effects of COVID‐19 in pregnant women in Colombia. Int J Gynecol Obstet, 151: 203-208. https://doi.org/10.1002/ijgo.13348

Study 419 – 31 cases from Pakistan

From 29th March to 9th May, 31/303  pregnant women tested positive for SARS-CoV-2 on admission in labour, of whom 29 had symptoms (click here or ANN_20_03_17). They were cared for in the Government Maternity Hospital, Gujrat, the Basic Health Unit, Fatehpur, Shaikh Zayed Hospital Lahore and DUHS Hospital Karachi, which have not previously reported cases.Citation: Ullah R, Memon FS, Anjum S. The alarming rate of COVID-19 among pregnant women in Pakistan. Anaesth. pain intensive care 2020;24(4):471-472. DOI: 10.35975/apic.v24i4.1325 

1st December update – studies 406 to 418 added

Study 418 – 86 cases from USA

Of 1,989 pregnant women screened for SARS-CoV-2, 86 (4.3%) tested positive (click here or An initiative to evaluate the safety of maternal bonding in patients with SARS CoV 2 infection). Rooming in, breastfeeding and neonatal infection are reported. The hospital was the University of Maryland School of Medicine, Baltimore. Apart from the single case in study 269 these are the first cases reported from that hospital. Citation: Liviu Cojocaru, Sarah Crimmins, Sripriya Sundararajan, Katherine Goetzinger, Emad Elsamadicy, Allison Lankford, Ozhan M. Turan & Sifa Turan (2020) An initiative to evaluate the safety of maternal bonding in patients with SARS-CoV-2 infection, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1828335. 

Study 417 – 8 pregnant women in ITU, Spain

Among 3,033 patients critically ill with Covid-19 in Vall dHebron University Hospital in Barcelona were eight pregnant women treated in intensive care (click here or 1-s2.0-S0213005X2030272X-main). All eight survived. They probably overlap with those in studies 140, 185 and 413. Citation: Ferrer R, Báguena M, Balcells J, Bañeras J, Biarnes A, de Nadal M, Gracia RM, Martinez J, Nuvials X, Riera J, Roca O, Ruiz-Rodriguez JC. Planning for the assistance of critically ill patients in a Pandemic Situation: The experience of Vall d’Hebron University Hospital. Enferm Infecc Microbiol Clin. 2020 Sep 8:S0213-005X(20)30272-X. English, Spanish. doi: 10.1016/j.eimc.2020.08.007. Epub ahead of print. PMID: 33010961.

Study 416 – Mother & newborn with Covid-19 from Mexico

A woman with severe Covid-19 at term required ventilation, and delivered a baby by Caesarean, who tested positive and had a clinical diagnosis of Covid-19 (click here or PIIS1201971220306846). Both mother and baby recovered. Both were treated at Hospital de Ginecología y Obstetricia, Instituto Materno Infantil del Estado de México, Toluca, which appears to be different from other hospitals reporting cases from that city in study 396, and has therefore probably not been previously reported. Citation: Hinojosa-Velasco A, de Oca PVB, García-Sosa LE, Mendoza-Durán JG, Pérez-Méndez MJ, Dávila-González E, Ramírez-Hernández DG, García-Mena J, Zárate-Segura P, Reyes-Ruiz JM, Bastida-González F. A case report of newborn infant with severe COVID-19 in Mexico: Detection of SARS-CoV-2 in human breast milk and stool. Int J Infect Dis. 2020 Nov;100:21-24. doi: 10.1016/j.ijid.2020.08.055. Epub 2020 Aug 27. PMID: 32860950; PMCID: PMC7449937.

Study 415 -388 pregnancies collected by WAPM

388 singleton pregnancies positive for Covid-19 from 73 centers in 22 countries collected by the World Association of Perinatal Medicine (click here or [16193997 – Journal of Perinatal Medicine] Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19)_ a secondary analysis of the WAPM study on COVID-19). These cases were also reported in studies 278 and 307. The centres are listed but not the number of cases per centre. Citation: Di Mascio D, Sen C, Saccone G, Galindo A, Grünebaum A, Yoshimatsu J, Stanojevic M, Kurjak A, Chervenak F. Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM study on COVID-19. J Perinat Med. 2020 Nov 26;48(9):950-958. doi: 10.1515/jpm-2020-0355. PMID: 32975205.

Study 414 – Low rate of symptomatic disease at birth

17/3,923 (0.43%) of pregnant women admitted to labor and delivery units in Kaiser Permanente Southern California (KPSC) hospitals between April 6 and May 11, who underwent SARSCoV-2 testing were positive (click here or s-0040-1714060). None had symptoms, although one woman developed a headache attributed to COVID-19 3 days postpartum. All babies tested negative. This is the first report from the Kaiser Permanante network. Citation: Fassett MJ, Lurvey LD, Yasumura L, Nguyen M, Colli JJ, Volodarskiy M, Gullett JC, Braun D, Fong A, Trivedi N, Bruxvoort K, Chiu V, Getahun D. Universal SARS-Cov-2 Screening in Women Admitted for Delivery in a Large Managed Care Organization. Am J Perinatol. 2020 Sep;37(11):1110-1114. doi: 10.1055/s-0040-1714060. Epub 2020 Jul 3. PMID: 32620022; PMCID: PMC7516390.

Study 413 – Two cases from Spain

Two women with severe Covid-19 requiring ventilation, one with twins, gave birth prematurely (click here or PIIS1875957220301455). All three babies tested negative and had an uneventful course. They were cared for in Vall d’Hebron University Hospital in Barcelona, so may overlap with studies 140, 185 and 196, as well as other Spanish registry studies. Citation: Fernandez-Garcia C, Montaner-Ramon A, Hernandez-Perez S, Camba-Longueira F, Ribes-Bautista C, Frick MA, Castillo-Salinas F. Severe COVID-19 during pregnancy and the subsequent premature delivery. Pediatr Neonatol. 2020 Sep 19:S1875-9572(20)30145-5. doi: 10.1016/j.pedneo.2020.09.005. Epub ahead of print. PMID: 33039313; PMCID: PMC7501516.

Study 412 – Abnormal bleeding at Caesarean in USA

A woman had abnormal bleeding at Caesarean, and subsequently tested positive for SARS-CoV-2 (click here or s12884-020-03140-2). From author affiliations she was cared for at Icahn School of Medicine at Mount Sinai West, New York, so might be included in studies 86, 119, and 131. Citation: Kinsey, K.E., Ganz, E., Khalil, S. et al. Intraoperative coagulopathy during cesarean section as an unsuspected initial presentation of COVID-19: a case report. BMC Pregnancy Childbirth 20, 481 (2020). https://doi.org/10.1186/s12884-020-03140-2

Study 411 – Eclampsia and Covid-19

A woman with eclampsia and cortical blindness at term who also tested positive for SARS-CoV-2 (click here or s12884-020-03275-2). She recovered. The baby outcome is not reported. She was cared for in the University Complex Hospital of Leon, which has not previously reported cases, but was included in other multicentre reports from Spain. Citation: Garcia Rodriguez A, Marcos Contreras S, Fernandez Manovel SM, Marcos Vidal JM, Diez Buron F, Fernandez Fernandez C, Riveira Gonzalez MDC. SARS-COV-2 infection during pregnancy, a risk factor for eclampsia or neurological manifestations of COVID-19? Case report. BMC Pregnancy Childbirth. 2020 Oct 6;20(1):587. doi: 10.1186/s12884-020-03275-2. PMID: 33023500; PMCID: PMC7538036.

Study 410 – Covid in a pregnant man with cystic fibrosis

A transgender man (genetically female, identifying as male) with cystic fibrosis contracted Covid-19 at 39 weeks gestation (click here or PIIS246804512030050X). The baby tested negative.  From author affiliations the patient was cared for in Sunshine Coast University Hospital, Queensland, Australia which has not previously reported cases. The case is likely to be the same as news report 220 (click here). Citation: Walczak A, Wilks K, Shakhovskoy R, Baird T, Schlebusch S, Taylor C, Reid D, Choong K. COVID-19 in a complex obstetric patient with cystic fibrosis. Infect Dis Health. 2020 Nov;25(4):239-241. doi: 10.1016/j.idh.2020.07.002. Epub 2020 Jul 23. PMID: 32763024; PMCID: PMC7379287.

Study 409 – Triplets from Iran

A woman with IVF triplets contracted Covid-19 and was delivered by Caesarean at 30 weeks (click here or IJN_Volume 11_Issue 3_Pages 120-122). She survived. The triplets all tested negative but two died of complications of prematurity. They were cared for in Arash Hospital, Tehran and appear to be the same triplets as case 5 in study 250. Citation: Farsi Z, Taheriderakhsh N, Bassirnia M, Ahmadi L, Shiva M, Yousefzadegan S. Coronavirus Disease-2019 Infection in Neonates of an Infected Pregnant Mother with Triplets. 2020 Sep: 11(3). DOI: 10.22038/ijn.2020.49218.1856

Study 408 – Post partum cardiomyopathy and Covid-19

A woman had experienced fever, cough, and altered sense of taste and smell a week before giving birth normally March 21(click here or echo.14873). On April 22 she developed cardiomyopathy and tested postive for SARS-CoV-2. She recovered. She was cared for in Luigi Sacco University Hospital, Milan, Italy, but it is not clear if she was included in the various Lombardy series. Citation: De Vita, SIppolito, SCaracciolo, MMBarosi, APeripartum cardiomyopathy in a COVID-19-infected woman: differential diagnosis with acute myocarditis—A case report from a Hub Institution during the COVID-19 outbreak. Echocardiography. 2020371673– 1677https://doi.org/10.1111/echo.14873

Study 407 – 26 cases from Quatar

There were 26 pregnant women with Covid-19 in this series (click here or s12879-020-05511-8). Two women miscarried, there were 10 live births and 14 pregnancies are ongoing. Cared for by Hamad Medical Corporation. Some cases are probably included in study 364. Citation: Omrani, A.S., Almaslamani, M.A., Daghfal, J. et al. The first consecutive 5000 patients with Coronavirus Disease 2019 from Qatar; a nation-wide cohort study. BMC Infect Dis 20, 777 (2020). https://doi.org/10.1186/s12879-020-05511-8

Study 406 – 43 cases from China

These 43 cases from Tongji Hospitalgrid.412793.a Wuhan, China, have surely been reported many times already (click here or pdf). Citation: Wei L, Gao X, Chen S, Zeng W, Wu J, Lin X, Zhang H, Mwamaka Sharifu L, Chen L, Feng L, Wang S. Clinical Characteristics and Outcomes of Childbearing-Age Women With COVID-19 in Wuhan: Retrospective, Single-Center Study. J Med Internet Res. 2020 Aug 24;22(8):e19642. doi: 10.2196/19642. PMID: 32750000; PMCID: PMC7446716.

30th November update – studies 397 to 405 added

Study 405 – 77 placentas from USA

The placental histology of 77 COVID-19 pregnancies are reported (click here or 1-s2.0-S0002937820311947-main). The patients were delivered at NYU Winthrop Hospital, New York so may have been included in studies 61 and 91. Citation: Patberg ET, Adams T, Rekawek P, Vahanian SA, Akerman M, Hernandez A, Rapkiewicz AV, Ragolia L, Sicuranza G, Chavez MR, Vintzileos AM, Khullar P. Coronavirus disease 2019 infection and placental histopathology in women delivering at term. Am J Obstet Gynecol. 2020 Oct 19:S0002-9378(20)31194-7. doi: 10.1016/j.ajog.2020.10.020. Epub ahead of print. PMID: 33091406; PMCID: PMC7571377.

Study 404 – Case report from USA

A woman contracted Covid-19 at 38 weeks (click here or 9796-Article Text-55170-2-10-20200902). She had altered liver enzymes but recovered. The baby was not infected. From author affiliations she was probably cared for in St. John’s Episcopal Hospital, Far Rockaway, New York, which has not previously reported cases. Citation: Nkeih C, Sisti G, Schiattarella A. Elevated transaminases in a COVID-19 positive patient at term of gestation: a case report: Covid19 and pregnancy. Acta Bio Med [Internet]. 2020Sep.7 [cited 2020Nov.30];91(3):e2020002. https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/9796

Study 402 – 9 cases from Nigeria

Nine pregnant women with COVID-19 gave birth at Lagos University Teaching Hospital (click here or ijgo.13436). Eight delivered by caesarean and there was one macerated stillbirth. This is the first series from this hospital although one case might be the same as in study 243. Citation: Banke‐Thomas, A., Makwe, C.C., Balogun, M., Afolabi, B.B., Alex‐Nwangwu, T.A. and Ameh, C.A. (2020), Utilization cost of maternity services for childbirth among pregnant women with coronavirus disease 2019 in Nigeria’s epicenter. Int J Gynecol Obstet. https://doi.org/10.1002/ijgo.13436

Study 401 – six cases from Mexico

Six women with Covid-19 underwent caesarean (click here or 1-s2.0-S2049080120303939-main). Two were admitted to ICU but no mothers or babies died. They were cared for in the General Hospital of Mexico “Dr. Eduardo Liceaga”, Mexico City, so might be included in study 340. Citation: Dra Mariel González-Calatayud, Dr Benito Vargas-Ábrego, Dra Gabriela E. Gutiérrez-Uvalle, Dra Sandra C. López-Romero, Dr Luis Gabriel González-Pérez, Dr José Alberto Carranco-Martínez, Dr Jed Raful-Zacarías-Ezzat, Dr Noé I. Gracida-Mancilla. Observational study of the suspected or confirmed cases of sars COV-2 infection needing emergency surgical intervention during the first months of the pandemic in a third level hospital: Case series, Annals of Medicine and Surgery, Volume 60, 2020, Pages 149-154, ISSN 2049-0801, https://doi.org/10.1016/j.amsu.2020.10.038.

Study 400 – six patients from Italy

Six women with Covid-19 and diabetes are reported (click here or ijgo.13434). They were cared for in Institution Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan,and therefore probably included in studies 64, 117, 163, 252, and 312. Citation: D’Ambrosi F, Rossi G, Soldavini CM, Maggi V, Cetera GE, Carbone IF, Di Martino D, Di Maso M, Ferrazzi E. Management of gestational diabetes in women with a concurrent Sars-Cov-2 infection, experience of a single center in Northern Italy. Int J Gynaecol Obstet. 2020 Oct 25. doi: 10.1002/ijgo.13434. Epub ahead of print. PMID: 33099770.

Study 399 – 95 cases from Turkey

95 pregnant women with Covid-19 (click here or jmv.26631). They were cared for at Turkish Ministry of Health Ankara City Hospital between May 11, and August 30, 2020.  They may have been included in studies 203, 223 and 244. Citation: Yazihan, N, Tanacan, A, Erol, SA, et al. Comparison of VEGF‐A values between pregnant women with COVID‐19 and healthy pregnancies and its association with composite adverse outcomes. J Med Virol. 2020; 1‐ 6. https://doi.org/10.1002/jmv.26631

Study 398 – Maternal death & twin pregnancy in Iran

A woman who had conceived twins via IVF, contracted Covid-19 at 28 weeks (click here or 30428-Article Text-131298-6-10-20201031). Mother and both twins died. She was cared for in Shohada-e-Tajrish Hospital, Tehran, which has not previously reported cases, and the clinical details differ from those in studies 23 and 218. Citation: Azizi FarsaniH, BehnazF, TeymourianH, MohseniG.Termination of Pregnancy in a Twin Pregnant Patient with COVID-19.J Cell Mol Anesth.2020;5(3):206-8.

Study 397 – Case Report from China

A woman with Covid-19 gave birth in Suzhou, by Caesarean at 30 weeks (click here or 13274-Article Text-114670-1-10-20201006). The baby was not infected. This may be the same case as study 257b. Citation: Xiaotong Wang, Zhiqiang Zhou, Jianping Zhang, Fengfeng Zhu, Yongyan Tang, Xinghua Shen, A Case of 2019 Novel Coronavirus in a Pregnant Woman With Preterm Delivery, Clinical Infectious Diseases, Volume 71, Issue 15, 1 August 2020, Pages 844–846, https://doi.org/10.1093/cid/ciaa200

29th November update – studies 387 to 394 added

Study 396 – 20 pregnant women with Covid-19 from Mexico

Twenty pregnant or postnatal women with Covid-19 were treated at “Mónica Pretelini Sáenz” Maternal Perinatal Hospital, or “Dr. Nicolás San Juan” General Hospital, both in Toluca (click here or 13274-Article Text-114670-1-10-20201006). Two mothers died, and of the 15 pregnancies which had ended, there were three fetal loses due to: ectopic pregnancy, fetal death at 16 weeks of pregnancy and a postnatal death from prematurity complications. Neither of these hospitals has previously reported cases, although the maternal deaths may have been included in studies 66, 271 and 340Citation: Meneses Calderón J, Figueroa Flores M del R, Paniagua Coria L, Briones Garduño JC, Meneses Figueroa J, Vargas Contretas MJ, de la Cruz Ávila L, Díaz Meza S, Ramírez Chacón R, Padmanabhan S, Mendieta Zerón H (2020) Nitazoxanide against COVID-19 in three explorative scenarios. J Infect Dev Ctries 14:982-986. doi: 10.3855/jidc.13274

Study 395 – 48 cases from China

Maternal and neonatal details reported (click here or 10-1055-s-0040-1716505). The babies were cared for in Tongji Hospital grid.412793.a and HuangShi [?Huazhong] Maternal and Child Healthcare Hospital grid.412793.a, Wuhan, from January 17 to March 4, 2020 so the pregnancies have been reported before. Citation: Liu W, Cheng H, Wang J, et al. Clinical Analysis of Neonates Born to Mothers with or without COVID-19: A Retrospective Analysis of 48 Cases from Two Neonatal Intensive Care Units in Hubei Province. Am J Perinatol. 2020;37(13):1317-1323. doi:10.1055/s-0040-1716505

Study 394 – Infarction of a pituitary tumour and Covid-19 in pregnancy in USA

A woman with visual disturbance at 38 weeks tested positive for SARS-CoV-2 (click here or Chan2020_Article_PituitaryApoplexyAssociatedWit). She delivered vaginally and the baby tested negative. Two weeks later a presumed infarcted pituitary tumour was removed. From author affiliations she was cared for at Cedars-Sinai Medical Center, Los Angeles, and therefore might be included in study 121. Citation: Chan, J.L., Gregory, K.D., Smithson, S.S. et al. Pituitary apoplexy associated with acute COVID-19 infection and pregnancy. Pituitary 23, 716–720 (2020). https://doi.org/10.1007/s11102-020-01080-w

Study 393 – zero cases in pregnancy in a hospital in Slovenia

None of 202 pregnant women tested for SARS-CoV-2 in the Ljubljana Maternity Hospital between March 15 and May 16, 2020 were positive (click here or full text not available). Citation: Šterbenc, A., Premru Sršen, T., Lučovnik, M., Vidmar Šimic, M., Steblovnik, L., Fabjan Vodušek, V., Druškovič, M., Kavšek, G., Poljak, M., & Trojner Bregar, A. (2020). Usefulness of COVID-19 screen-and-test approach in pregnant women: an experience from a country with low COVID-19 burden, Journal of Perinatal Medicine (published online ahead of print 2020), 000010151520200368. doi: https://doi.org/10.1515/jpm-2020-0368

Study 392 – two cases from USA

Two babies born to women with moderately severe Covid-19 are reported (click here or 10-1055-s-0040-1715180). From author affiliations the patients were cared for at Rutgers University, Robert Wood Johnson Medical School, New Brunswick, New Jersey. The mothers may therefore have been included in studies 86 and 285. Citation: Reddy A, Engelhardt K, Jain D. Air Leak Syndrome in Two Very Preterm Infants Born to Mothers with Coronavirus Disease 2019: An Association or a Coincidence?. AJP Rep. 2020;10(3):e266-e269. doi:10.1055/s-0040-1715180

Study 391 – 23 cases from USA

Of 23 pregnant women who tested positive for SARS-CoV-2, 13 had symptoms but none severe disease (click here or Dhuyvetter2020_Article_CoronavirusDisease2019InPregna). They were cared for at John H Stroger Hospital in Chicago, Illinois which has not previously reported cases. Citation: Dhuyvetter, A., Cejtin, H.E., Adam, M. et al. Coronavirus Disease 2019 in Pregnancy: The Experience at an Urban Safety Net Hospital. J Community Health (2020). https://doi.org/10.1007/s10900-020-00940-7

Study 390 – 248 infants from Spain

Breastfeeding rates among 242 mothers with Covid-19 and 248 live newborn infants (click here or PIIS0301211520306400). The infants were born in 15 Spanish hospitals, who were members of the Neo-COVID-19 research group, between 13 March and 31 May, and therefore probably overlap with those in studies 264b and 366. Citation: del Río R, Dip Pérez E, Marín Gabriel MÁ; the Neo-COVID-19 Research Group. Multi-centre study showed reduced compliance with the World Health Organization recommendations on exclusive breastfeeding during COVID-19. Acta Paediatr. 2020;00:1–2. https://doi.org/10.1111/apa.15642

Study 389 – Forceps birth in the ITU in USA

A woman with severe Covid-19 who had already required 5 days ventilation was induced and delivered vaginally by forceps at 33 weeks in the ITU (click here or Induction_of_Labor_in_an_Intubated_Patient_With.15). The perineum was intact. The baby tested negative. The mother required a further 4 days ventilation but recovered. From author affiliations she was cared for at Legacy Salmon Creek Hospital, Vancouver, Washington State, which has not previosly reported cases. Citation: Slayton-Milam, Suzanne MD; Sheffels, Samantha BS; Chan, Dominic PharmD, BCPS (AQ-ID); Alkinj, Bashar MD Induction of Labor in an Intubated Patient With Coronavirus Disease 2019 (COVID-19), Obstetrics & Gynecology: November 2020 – Volume 136 – Issue 5 – p 962-964 doi: 10.1097/AOG.0000000000004044

Study 388 – case report from USA

A woman with severe Covid-19 at 22 weeks (click here or Tocilizumab_and_Remdesivir_in_a_Pregnant_Patient.25). She recovered and the pregnancy is ongoing. From author affiliations she was cared for at Cedars Sinai Medical Center, Los Angeles, California, and therefore might be included in study 121. Citation: Naqvi, Mariam MD; Zakowski, Phillip MD; Glucksman, Lindsey MD; Smithson, Sarah DO, MS; Burwick, Richard M. MD, MPH Tocilizumab and Remdesivir in a Pregnant Patient With Coronavirus Disease 2019 (COVID-19), Obstetrics & Gynecology: November 2020 – Volume 136 – Issue 5 – p 1025-1029 doi: 10.1097/AOG.0000000000004050

Study 387 – 22 cases from USA

Outpatient care of 22 pregnant women with Covid-19 (click here or main (5)). They were cared for at Beth Israel Deaconess Medical Center, Massachusetts, so may have been included in studies 129 and 231. Citation: Reforma LG, Duffy C, Collier AY, et al. A multidisciplinary telemedicine model for management of coronavirus disease 2019 (COVID-19) in obstetrical patients. Am J Obstet Gynecol MFM. 2020;2(4):100180. doi:10.1016/j.ajogmf.2020.100180

28th November update – studies 379 to 386 added

Study 386 – Case from Greece

A patient with mild Covid-19 at term gave birth by Caesarean (click here or JAnaesthClinPharmacol365121-6656644_182926). The authors state this was the first case in this country. From their affiliations the hospital was “Attikon” University Hospital, Athens. Citation: Batistaki C, Galarioti V, Vasiliadou S, Soulioti E, Kostopanagiotou G, Matsota P. Lessons learned from first case of Cesarean delivery in a COVID-19 positive parturient in Greek region. J Anaesthesiol Clin Pharmacol. 2020;36(Suppl 1):S121-S124. doi:10.4103/joacp.JOACP_157_20

Study 385 – Case from India

A pregnant woman had mild Covid-19 at 37 weeks (click here or JAnaesthClinPharmacol36577-6694834_183548). She was delivered by Caesarean under spinal anaesthesia. The baby tested negative. From author affiliations the hospital was Gian Sagar Medical College and Hospital, Banur, Patiala. Citation: Bajwa SJS, Gupta R, Wahi A, Goraya SPS. Exploring the unknown territories in the new normal world of COVID. J Anaesthesiol Clin Pharmacol. 2020;36(Suppl 1):S77-S80. doi:10.4103/joacp.JOACP_350_20

Study 384 – Seroconversion among maternity workers in London

In two London hospitals 29/200 (15%) of obstetric healthcare professionals seroconverted between 11 May 2020 and 5 June 2020 (click here or anae.15229). From author affiliations the hospitals were probably University College London Hospitals NHS Foundation Trust, and Northwick Park Hospital. Citation: Bampoe, S., Lucas, D.N., Neall, G., Sceales, P., Aggarwal, R., Caulfield, K., Siassakos, D. and Odor, P.M. (2020), A cross‐sectional study of immune seroconversion to SARS‐CoV‐2 in frontline maternity health professionals. Anaesthesia, 75: 1614-1619. https://doi.org/10.1111/anae.15229

Study 383 – Follow up of 138 cases from China

This important study reports three month follow-up of 72/138 pregnant women with Covid-19 collected by the National Epidemic Reporting System (NERS) in China (click here or s12916-020-01825-1). All 13 first trimester cases were aborted. In supplementary table 1 (click here or 12916_2020_1825_MOESM1_ESM) it appears that one of the 138 original mothers died; the first report of a maternal death from Covid-19 in China. The cases overlap with those in study 55 and other Chinese reports. Citation: Wang, Y., Chen, L., Wu, T. et al. Impact of Covid-19 in pregnancy on mother’s psychological status and infant’s neurobehavioral development: a longitudinal cohort study in China. BMC Med18, 347 (2020). https://doi.org/10.1186/s12916-020-01825-1

Study 382 – 64 cases from Turkey

Of 64 pregnant women with suspected Covid-19, 33 tested positive (click here or PCR positivity and D-dimer levels in pregnant women with COVID-19). Limited clinical information is presented, but one woman underwent thoracotomy. From author affiliation they were cared for in Kocaeli Derince Training and Research Hospital, Kocaeli, so some may have been included in study 244. Citation: K. Uzel, I. Lakhno. PCR positivity and D-dimer levels in pregnant women with COVID-19. Clin. Exp. Obstet. Gynecol. - ISSN: 0390-6663 XLVII, n. 5, 2020. doi: 10.31083/j.ceog.2020.05.2229

Study 381 – 111 patients with suspected COVID-19 in Spain

In this paper 68 pregnant women who tested positive were compared with 43 who tested negative (click here or jcm-09-03552-v2). The negative group included nine women with both symptoms and radiological findings of pneumonia, one of whom later developed anti SARS-CoV-2 antibodies. The women were cared for in University Hospital Gregorio Marañón, Madrid. They probably overlap with those reported in study 151 and possibly 196. Citation: Cuñarro-López, Y.; Cano-Valderrama, Ó.; Pintado-Recarte, P.; Cueto-Hernández, I.; González-Garzón, B.; García-Tizón, S.; Bujan, J.; Asúnsolo, Á.; Ortega, M.A.; De León-Luis, J.A. Maternal and Perinatal Outcomes in Patients with Suspected COVID-19 and Their Relationship with a Negative RT-PCR Result. J. Clin. Med. 2020, 9, 3552.

Study 380 – 66 cases from Pakistan

66 women who tested positive for SARS-CoV-2 in pregnancy between 27th April and 16th June 2020, were mostly asymptomatic (click here or Bulletin_pdf). No babies were infected. From author affililiations they were cared for at the Indus Hospital, Karachi, which has not previously reported cases. These may be the first reported cases from this country. Citation: Khan M.A., Kumar V., Ali S.R. Vertical Transmission of Novel Coronavirus (COVID-19) from Mother to Newborn: Experience from a Maternity Unit, The Indus Hospital, Karachi. Journal of the College of Physicians and Surgeons–Pakistan : JCPSP. 30 (10) (pp 136), 2020. Date of Publication: 01 Oct 2020.

Study 379 – 34 cases from China

These 34 cases (click here or ofaa283) cared for in Union Hospital Wuhan (grid.412839.5) between January 15 & March 15, 2020, likely overlap with those in  studies 2a, 2b, 2c, 5*, and 6). Citation: Xu S, Shao F, Bao B, et al. Clinical Manifestation and Neonatal Outcomes of Pregnant Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China. Open Forum Infect Dis. 2020;7(7):ofaa283. Published 2020 Jul 5. doi:10.1093/ofid/ofaa283

27th November update – studies 373 to 378 added

Study 378 – Zero pregnancy cases in one prefecture, Japan

805 pregnant women (half of all women giving birth in the region) were tested for SARS-CoV-2 in Fukui prefecture, Japan between April 24 to July 25, 2020 (click here or jog.14567). All tested negative, and later checking against case notifications of COVID‐19, revealed no missed cases. Fukui had a SARS-CoV-2 prevalence of 16.5/100.000 during this period. Citation: Orisaka, M., Kawamura, H. and Yoshida, Y. (2020), COVID‐19 testing of pregnant women in Japan. J. Obstet. Gynaecol. Res.. https://doi.org/10.1111/jog.14567

Study 377 – Co-infection with rhinovirus & SARS-CoV-2 in pregnancy

A woman was infected with both SARS-CoV-2 and Rhinovirus/Enterovirus at 31 weeks gestation (click here or 21928959 – Case Reports in Perinatal Medicine] A case report of co-infection with rhinovirus and SARS-CoV-2 in pregnancy). She had mild symptoms but recovered and the pregnancy is ongoing. The authors are affiliatated with Renaissance School of Medicine Stony Brook University, Stony Brook, New York, USA, which has not previously reported cases. Citation: Heiselman, C. J., Iovino, N., & Herrera, K. M. (2020). A case report of co-infection with rhinovirus and SARS-CoV-2 in pregnancy, Case Reports in Perinatal Medicine, 9(1), 20200028. doi: https://doi.org/10.1515/crpm-2020-0028

Study 376 – Infected baby from USA

A woman contracted Covid-19 at 36 weeks and was delivered by Caesarean (click here or piaa109). The baby was asymptomatic but tested positive. The baby was born at Presbyterian Brooklyn Methodist Hospital in New York and therefore may be included in study 230. Citation: Ihab Alamar, Mohammad H Abu-Arja, Taryn Heyman, Drucilla J Roberts, Niyati Desai, Pramod Narula, Beata Dygulska, A Possible Case of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Newborn With Positive Placental In Situ Hybridization of SARS-CoV-2 RNA, Journal of the Pediatric Infectious Diseases Society, Volume 9, Issue 5, November 2020, Pages 636–639, https://doi.org/10.1093/jpids/piaa109

Study 375 – 50 cases from Iran

Of 50 pregnant women hospitalised with Covid-19 in Hamadan (alt. spelling Hamedan) Province, 2 mothers died, 7 babies were infected and 26 women remain undelivered (click here or jrhs-20-e00488). The hospitals are unnamed and cannot be guessed at from author affliliations. Hamadan province is remote from Tehran, Ilam, Tabriz, and Sari from which most Iranian reports of maternal disease have come. However, study 250 included some infected babies from Hamadan province, and the two maternal deaths may have been included in studies 23 and 67. Citation: Sattari M, Bashirian S, Masoumi SZ, Shayan A, Jenabi E, Ghelichkhani S, Ali Shirzadeh A, Jalili E, Alimohammadi S. Evaluating Clinical Course and Risk Factors of Infection and Demographic Characteristics of Pregnant Women with COVID-19 in Hamadan Province, West of Iran. J Res Health Sci. 2020; 20(3): e00488.

Study 374 – 44 advice calls to a teratology service in Italy

This report describes 44 advice calls to a teratology service in Bergamo in Lombardy concerning drug prescription to 16 pregnant or lactating women with suspected, and 28 with confirmed, Covid-19 (click here or [16193997 – Journal of Perinatal Medicine] Medications prescriptions in COVID-19 pregnant and lactating women_ the Bergamo Teratology Information Service experience during COVID-19 outbreak in Italy). Citation: Giampreti, A., Eleftheriou, G., Gallo, M., Butera, R., Contessa, G., Faraoni, L., Sangiovanni, A., Negri, G., Falchi, G., & Bacis, G. (2020). Medications prescriptions in COVID-19 pregnant and lactating women: the Bergamo Teratology Information Service experience during COVID-19 outbreak in Italy, Journal of Perinatal Medicine, 48(9), 1001-1007. doi: https://doi.org/10.1515/jpm-2020-0339

Study 373 – Case report from the Netherlands

A woman contracted severe Covid-19 at 23 weeks requiring prolonged ventilation and Caesarean delivery at 28 weeks (click here or main (2)). The mother survived. The baby suffered complications of prematurity but was not infected and survived. From author affiliations she was cared for at Leiden University Medical Center. Apart from NethOSS reports, the case has not been previously reported. The centre and clinical features differ from the case in study 263. Citation: du Fossé NA, Bronsgeest K, Arbous MS, et al. Detailed immune monitoring of a pregnant woman with critical Covid-19 [published online ahead of print, 2020 Oct 29]. J Reprod Immunol. 2020;143:103243. doi:10.1016/j.jri.2020.103243

26th November update – studies 368 to 372 added

Study 372 – A case of thyroiditis following post-partum Covid-19 in Japan

A woman contracted Covid-19, 103 days after giving birth, and 33 days later was diagnosed with thyroiditis (click here or advpub_EJ20-0553). From author affililiations the thyroiditis was treated at Wakayama Medical University, Wakayama. Citation: Mizuno S, Inaba H, Kobayashi KI, Kubo K, Ito S, Hirobata T, Inoue G, Akamizu T, Komiya N. A case of postpartum thyroiditis following SARS-CoV-2 infection. Endocr J. 2020 Nov 12. doi: 10.1507/endocrj.EJ20-0553. Epub ahead of print. PMID: 33177251.

Study 371 – 40 cases in USA

Of 40 pregnant women with SARS-CoV-2 cared for in the Nuvance healthcare system, 3/4 had symptoms and 25 delivered (click here or full text not accessed). Of 20 neonates tested for SARS-CoV-2 all were negative. Nuvance maternity hospitals include Vassar Brothers, and Norwalk hospitals, in New York State and Connecticut, neither of which have previously reported cases. Citation: Ogamba, I., Kliss, A., Rainville, N., Chuang, L., Panarelli, E., Petrini, J., & Zilberman, D. (2020). Initial review of pregnancy and neonatal outcomes of pregnant women with COVID-19 infection, Journal of Perinatal Medicine (published online ahead of print 2020), 000010151520200446. doi: https://doi.org/10.1515/jpm-2020-0446

Study 370 – A postnatal woman treated with ECMO in Japan

A woman with Covid-19 at 36 weeks gestation was delivered by Caesarean (click here or amjcaserep-21-e927521). The baby tested negative but the mother’s condition deteriorated, necessitating ventilation and later ECMO. She recovered. She was delivered in an unnamed general hospital in Tokyo, and from author affiliations the postnatal intensive care probably took place at Tokyo Medical and Dental University Hospital, Tokyo. These, and the clinical features, suggest she has not been included in previous series from Japan. Citation: Takayama W, Endo A, Yoshii J, et al. Severe COVID-19 Pneumonia in a 30-Year-Old Woman in the 36th Week of Pregnancy Treated with Postpartum Extracorporeal Membrane Oxygenation. Am J Case Rep. 2020;21:e927521. Published 2020 Oct 28. doi:10.12659/AJCR.927521

Study 369 – 3 pregnant women with Covid-19 & malaria, and one with dengue from India

All four survived although one of the women with malaria experienced an intrauterine fetal death at 24 weeks (click here or ijgo.13415). They were cared for in Nair hospital in Mumbai, so may have been included in studies 225 & 283. Citation: Mahajan, N.N., Kesarwani, S.N., Shinde, S.S., Nayak, A., Modi, D.N., Mahale, S.D. and Gajbhiye, R.K. (2020), Co‐infection of malaria and dengue in pregnant women with SARS‐CoV‐2. Int. J. Gynecol. Obstet., 151: 459-462. https://doi.org/10.1002/ijgo.13415

Study 368 – Covid-19 in a pregnant renal transplant recipient

A woman who was 30 weeks pregnant with a renal transplant contracted Covid-19 (click here or 40620_2020_Article_897). She recovered and gave birth normally at term. The baby was not tested. From author affiliations she was probably cared for at Queen Charlottes & Chelsea Hospital in London, UK, which has not previously reported cases.  Citation: Gleeson S, Noori M, Lightstone L, Webster P. Lesson for the clinical nephrologist: Kidney transplant, COVID-19 and pregnancy [published online ahead of print, 2020 Nov 12]. J Nephrol. 2020;1-3. doi:10.1007/s40620-020-00897-9

25 November update – studies 362 to 367 added

Study 367 – Two cases from Italy

Santo Stefano Hospital in Prato, in Tuscany treated two cases of Covid-19 in pregnancy (click here or Cavaliere) and has not previously reported cases. Citation: A. F. Cavaliere, P. L. Vasarri, E. Scatena, A. Vidiri, M. S. Santicchia, I. Bordoni Vicini, M. Gardelli, F. Bressan, D. Matarrese, F. Perelli. SARS-CoV2 containment during pregnancy: single Center experience and the unique Chinese reality in Prato. Italian Journal of Gynæcology & Obstetrics September 2020 – Vol.32 – N. 3 – Quarterly – ISSN 2385 – 0868 

Study 366 – 403 cases from Spain

These 403 cases of Covid-19 in pregnancy were divided into 231 with early cord clamping and 172 with delayed (click here or 1471-0528.16597). Two and three infants respectively tested positive. The cases were selected from the Spanish Registry of COVID-19 which collects cases from 100 Spanish hospitals. Citation: Mejía Jiménez, I., Salvador López, R., García Rosas, E., de la Torre, I.R., Montes García, J., de la Cruz Conty, M.L., Martínez Pérez, O. and (2020), Umbilical cord clamping and skin‐to‐skin contact in deliveries from women positive for SARS‐CoV‐2: a prospective observational study. BJOG: An International Journal of Obstetrics & Gynaecology. Accepted Author Manuscript. https://doi.org/10.1111/1471-0528.16597

Study 365 – 3 cases from UK

Three pregnant women were included in this series from Southampton General Hospital, UK (click here or 1-s2.0-S0163445320306381-main). No further details are given. Citation: N.J. Brendish, S. Poole, V.V. Naidu et al., Clinical characteristics, symptoms and outcomes of 1054 adults presenting to hospital with suspected COVID-19: A comparison of patients with and without SARS-CoV-2 infection, Journal of Infection, https://doi.org/10.1016/j.jinf.2020.09.033

Study 364 – 678 cases from Qatar

There were 678 pregnant women testing positive for SARS-CoV-2 in this preprint (click here or main (1)). These are the first pregnant cases reported from Quatar. Citation: Ehab Hamed, Ahmed Sameer Alnuaimi, Mohamed Ahmed Syed, Mohamed Abd Elhamid , Saad Thamer Sedeeq , Bayan Alemrayat , Amina Ali Mohamed Muktar, AlAnoud Saleh AlFehaidi , Hamda Abdulla A/Qotba, Clinical characteristics of 51815 patients presenting with positive and negative SARS-CoV-2 swab results in primary health care settings, Journal of Infection (2020), doi: https://doi.org/10.1016/j.jinf.2020.11.014. Final published version(click here or PIIS016344532030709X)

Study 363 – A maternal death from Birmingham UK

A woman with Covid-19 in pregnancy was ventilated and transferred elsewhere for ECMO but died (click here). Full text not available, so it is not yet clear if the case has been reported elsewhere. Citation: Stout A, Crichton R, Tahmasebi F. Maternal death secondary to COVID-19 infection: A case report and review of the literature. Obstetric Medicine. November 2020. doi:10.1177/1753495X20970816

Study 362 – Case report from USA

A case of severe COVID-19 pneumonia in a periviable pregnancy treated with concurrent combination of remdesivir, corticosteroids, and convalescent plasma therapy, leading to rapid maternal pulmonary improvement (click here or ). Full text not yet obtained. From author affiliation cared for at St. Mary’s Hospital-St. Louis, Missouri, which has not previously reported cases. Citation: Lam H., Lacasse A.  Combination of remdesivir, corticosteroid, and convalescent plasma for severe COVID-19 in periviable pregnancy. Infectious Diseases in Clinical Practice. 28 (6) (pp e21-e23), 2020. Date of Publication: 01 Nov 2020.

24th November update – studies 359 to 361 added

Study 361 – 252 cases from Texas

252 pregnant women who tested positive for SARS-CoV-2 were compared with 3,122 who tested negative (click here or adhikari_2020_oi_200933_1605126584.8159). There was no difference in a primary composite outcome of birth <37 weeks, severe pre-eclampsia, or cesarean for abnormal fetal heart rate. There were no maternal deaths in either group. No babies died in the SARS-CoV-2 group. Women were cared for at Parkland Health and Hospital System, Dallas. Citation: Adhikari EH, Moreno W, Zofkie AC, et al. Pregnancy Outcomes Among Women With and Without Severe Acute Respiratory Syndrome Coronavirus 2 Infection. JAMA Netw Open. 2020;3(11):e2029256. doi:10.1001/jamanetworkopen.2020.29256

Study 360 – 21 cases from Israel

21 women with Covid-19 all gave birth to healthy babies, one of whom tested positive (click here or Lopian PedNeo). They were cared for in Mayanei Hayeshua Medical Center in Bnei Brak, which has not previously reported cases. Citation: Lopian M et al., Safety of vaginal delivery in women infected with COVID-19, Pediatrics and Neonatology, https://doi.org/10.1016/j.pedneo.2020.10.010

Study 359 – 39 severe cases from US 

In this case control study, 39 pregnant women with severe or critical Covid-19 were compared with 94 non-pregnant women (click here or DeBolt AJOG). They were cared for in four academic medical centers in New York and one in Philadelphia. Some or all of the pregnant women have probably been previously reported in studies 85, 86, 91, 98, 152, 160, 175 and 350. Citation: DeBolt CA, Bianco A, Limaye MA, Silverstein J, Penfield CA, Roman AS, Rosenberg HM, Ferrara L, Lambert C, Khoury R, Bernstein PS, Burd J, Berghella V, Kaplowitz E, Overbey JR, Stone J, Pregnant women with severe or critical COVID-19 have increased composite morbidity compared to non-pregnant matched controls, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.11.022.

23rd November update – studies 357 and 358 added

Study 358 – A case from Brazil

A woman contracted severe Covid-19 at 27 weeks gestation, the fetus died in utero, was delivered by Caesarean section and tested positive (click here). The mother required ventilation but recovered. From author affiliations she was cared for in Hospital de Clínicas da Universidade Federal do Paraná, Parana. Citation: Stonoga ETS, Lanzoni LA, Rebutini PZ, Olveira ALP, Chiste JA, Fugaça CA, et al. Intrauterine transmission of SARS-CoV-2. Emerg Infect Dis. 2021 Feb [date cited]. https://doi.org/10.3201/eid2702.203824

Study 357 – A case from China

Among 67 cases of COVID-19 in Wenzhou, one was in a pregnant woman (click here or s12879-020-05528-z). No details are given of her, but all patients survived. They were cared for in Ruian People’s Hospital grid.452885.6 which has not previously reported cases. Citation: Hong, L., Ye, E., Sun, G. et al. Clinical and radiographic characteristics, management and short-term outcomes of patients with COVID-19 in Wenzhou, China. BMC Infect Dis 20, 841 (2020). https://doi.org/10.1186/s12879-020-05528-z

22nd November update – studies 353 to 356 added

Study 356 – 15 women from Italy

Among 15 pregnant women with SARS-CoV-2 none delivered infected infants (click here or fped-08-565522). They were cared for at City Hospital in Piacenza from late February through May 15, 2020. Although just outside Lombardy they have probably been reported in studies 32, 64 and 117. Citation: Biasucci G, Cannalire G, Raymond A, Capra ME, Benenati B, Vadacca G, Schiavo R, Pavesi C, Bonini R. Safe Perinatal Management of Neonates Born to SARS-CoV-2 Positive Mothers at the Epicenter of the Italian Epidemic. Front Pediatr. 2020 Oct 29;8:565522. doi: 10.3389/fped.2020.565522. PMID: 33194893; PMCID: PMC7658585.

Study 355 – Two cases from Northwestern China

Among 617 COVID-19 patients in this region, over 1,000km from Wuhan, two were pregnant, and one gave birth to a healthy baby at term. The outcome of the other was not reported. The exact location of neither was reported. Citation: Zhu J, Zhang Q, Jia C, et al. Epidemiological Characteristics and Clinical Outcomes of Coronavirus Disease Patients in Northwest China: High-Volume Research From Low Population Density Regions. Front Med (Lausanne). 2020;7:564250. Published 2020 Oct 30. doi:10.3389/fmed.2020.564250

Study 354 –  First trimester case from France

A woman with an ivf pregnancy contracted Covid-19 at 7 weeks (click here or s12879-020-05551-0). Prior to the diagnosis she had been treated with estradiol, progesterone, corticosteroids, chloroquine, aspirin & heparin. Liver enzymes were raised. She recovered. The pregnancy was ongoing at the time of the report. From author affiliations she was cared for at Hôpital Privé de Parly 2, Le Chesnay, Paris. Citation: Lamazou, F., Oger, P., Dieli-crimi, R. et al. COVID-19 infection in first trimester of pregnancy marked by a liver cytolysis in a woman previously treated by hydroxychloroquine for repeated implantation failure: a case report. BMC Infect Dis 20, 845 (2020). https://doi.org/10.1186/s12879-020-05551-0

Study 353 – Anaphylaxis after convalescent plasma therapy

A woman with Covid-19 at 31 weeks gestation experienced an anaphylactic reaction after treatment with convalescent plasma (click here or 1-s2.0-S0012369220330798-main). She required delivery. Neither mode of birth nor outcome for mother or baby was reported. The hospital was unnamed and no author affiliations are given. Citation: MARGARET MALLARI SREEJA SOMPALLI SHAISTA NOORMOHAMMAD ISHITA MALIK AND SIVASHANKAR SIVARAMAN. ANAPHYLACTIC SHOCK IN A PREGNANT PATIENT WITH COVID-19 IN THE SETTING OF CONVALESCENT PLASMA TRANSFUSION. CHEST, Volume 158, Issue 4, A959

15 November update – study 352 added

Study 352 – infected stillbirth in Portugal

An asymptomatic woman gave birth to a hydropic stillborn fetus at 34 weeks (click here or PIIS0301211520307533). Both mother and fetus tested positive for SARS-CoV-2. From author affiliations she was cared for at Hospital Prof. Doutor Fernando Fonseca, Amadora, which has not previously reported cases. Citation: Rodrigues ML, Gasparinho G, Sepulveda F, Matos T, Signs suggestive of congenital SARS-CoV-2 infection with intrauterine fetal death: a case report, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.11.042

11 November update – study 351 added

Study 351 – SARS-CoV-2 seroprevalence in antenatal samples in Australia

This anonymised seroprevalence study on samples collected between April & June 2020 in Sydney, included 560 samples from women undergoing antenatal screening. 0.79% were positive for SARS-CoV-2 IgG (click here or Gidding mja20.01971 – 11 November 2020_0). Citation: Heather F Gidding, Dorothy A Machalek, Alexandra J Hendry, Helen E Quinn, Kaitlyn Vette, Frank H Beard, Hannah Shilling, Rena Hirani, Iain B Gosbell, David O Irving, Linda Hueston, Marnie Downes, John B Carlin, Matthew NV O’Sullivan, Dominic E Dwyer, John M Kaldor and Kristine Macartney. Seroprevalence of SARS-CoV-2-specific antibodies in Sydney, Australia following the first epidemic wave in 2020 Med J Aust. Published online: 11 November 2020

10 November update – studies 349 and 350 added

Study 350 – 8 pregnant women detected by screening in USA

Of 318 pregnant women screened between April 13th & 26th, 2020, eight tested positive for Sars-CoV-2 (click here or Bender AJOG MFM main). The women were screened in the Hospital of the University of Pennsylvania and Pennsylvania Hospital, and may overlap with some reported in studies 65, 86, 175, and 202Citation: Bender WR, Hirshberg A, Coutifaris P, et al. Universal testing for severe acute respiratory syndrome coronavirus 2 in 2 Philadelphia hospitals: carrier prevalence and symptom development over 2 weeks. Am J Obstet Gynecol MFM 2020;2:100226.
https://doi.org/10.1016/j.ajogmf.2020.100226

Study 349 – 66 babies with neonatal SARS-CoV-2 infection in UK

Of 66 neonates with confirmed SARS-CoV-2 infection, 28 (42%) had severe disease,16 (24%) were born preterm and one died of an unrelated cause (click here or Gale Lancet PIIS2352464220303424). However, only two babies (3%) were considered to have possible vertically acquired infection (SARS-CoV-2-positive sample within 12 h of birth where the mother was also positive). Citation: Gale, Chris et al. Characteristics and outcomes of neonatal SARS-CoV-2 infection in the UK: a prospective national cohort study using active surveillance. The Lancet Child & Adolescent Health, Volume 0, Issue 0 DOI: https://doi.org/10.1016/S2352-4642(20)30342-4&nbsp; [important]

9th November update – study 342 (update of 203) and 343 to 348 added

Study 348 – 33 patients from USA

Of 33 women with Covid-19, two required ventilation and one died (click here or Curi AJOG MFM). The were two intrauterine fetal deaths. Patients were cared for at Lincoln Hospital Medical and Mental Health Center, South Bronx, which has not previously reported cases. Citation: Berenice Curi, Alexander Sabre, Israel Benjamin, Lisa Serventi, Dilfuza Nuritdinova. Coronavirus infection in a high-risk obstetrical population of the South Bronx, New York, American Journal of Obstetrics & Gynecology MFM, Volume 2, Issue 4, Supplement, 2020, 100203, ISSN 2589-9333, https://doi.org/10.1016/j.ajogmf.2020.100203. (http://www.sciencedirect.com/science/article/pii/S2589933320301725)

Study 347 – Case report from Monterrey, Mexico

A woman contracted severe Covid-19 at 27 weeks (click here or ijgo.13467). She required four days ventilation and was also treated with enoxaparin, azithromycin, ceftaroline, lopinavir/ritonavir, methylprednisolone and convalescent plasma. She recovered and delivered a growth restricted baby (birth weight not reported) at 39 weeks. The hospital was San José Tec Salud which has not previously reported cases. However, she may be included in study 340. Citation: Magallanes‐Garza, G.I., Valdez‐Alatorre, C., Dávila‐González, D., Martínez‐Reséndez, M.F., Sánchez‐Salazar, S.S., Castilleja‐Leal, F. and Cardona‐Huerta, S. (2020), Rapid improvement of a critically ill obstetric patient with SARS‐CoV‐2 infection after administration of convalescent plasma. International Journal of Gynecology & Obstetrics. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13467

Study 346 – 4 cases from France

Two women with Covid-19 delivered infected babies (click here or hascoet fped-08-568979). Two others delivered uninfected babies. From author affiliations they were likely cared for at Maternite Regionale CHRU Nancy, and therefore probably included in study 150Citation: Hascoët Jean-Michel, Jellimann Jean-Marc, Hartard Cedric, Wittwer Apolline, Jeulin Hélène, Franck Patricia, Morel Olivier. Case Series of COVID-19 Asymptomatic Newborns With Possible Intrapartum Transmission of SARS-CoV-2. Frontiers in Pediatrics VOLUME=8. 2020. P 632. URL=https://www.frontiersin.org/article/10.3389/fped.2020.568979. DOI=10.3389/fped.2020.568979

Study 345 – 15 maternal deaths from Covid-19 in Iran

Of 32 women who tested positive at Firoozgar General Hospital, Tehran, 15 died (click here or Moghadam ijgo.13461). Although this hospital has not previously reported cases, overlap with cases in studies 23, 67 & 218 cannot be excluded. Citation: Moghadam, S.A., Dini, P., Nassiri, S., Motavaselian, M., Hajibaba, M. and Sohrabi, M. (2020), Clinical features of pregnant women in Iran who died due to COVID‐19. Int J Gynecol Obstet. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13461

Study 344 – Case report from USA

A woman with Covid-10 was delivered by Caesarean on 3 April (click here or 2050313×20945536). She and the baby were fine. The patient was treated in Lehigh Valley Hospital, Stroudsburg, Pennsylvania, which has not previously reported cases.  Citation: Krupa Daniel, Kiran Goli, Anita Sargent. Repeat cesarean section in a COVID-19 positive mother in the United States. SAGE Open Medical Case Reports Volume 8: 1–3. 2020.  DOI: 10.1177/2050313X20945536

Study 343 – 32 cases from Jodhpur, India

32 women with Covid-19 during prepgnany were seen over 5 months from April to August 2020 (click here or ijgo.13457). Few details given. The paper is largely concerned with indirect effects of the pandemic. Citation: Goyal, M., Singh, P., Singh, K., Shekhar, S., Agrawal, N. and Misra, S. (2020), The effect of the COVID‐19 pandemic on maternal health due to delay in seeking health care: Experience from a tertiary center. International Journal of Gynecology & Obstetrics. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13457

Study 342 – an update of study 203 from Turkey

The 100 cases in study 203 have been expanded to 533 cases (click here or ijgo.13460). Two women died. There were 131 births and all neonatwes tested negative. Citation: Sahin, D., Tanacan, A., Erol, S.A., Anuk, A.T., Yetiskin, F.D., Keskin, H.L., Ozcan, N., Ozgu‐Erdinc, A.S., Eyi, E.G., Yucel, A., Tayman, C., Unlu, S., Dinc, B., Sari, E., Surel, A.A. and Moraloglu, O.T. (2020), Updated experience of a tertiary pandemic center on 533 pregnant women with COVID‐19 infection: A prospective cohort study from Turkey. Int J Gynecol Obstet. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13460

5th November update – studies 340 and 341 added

Study 341 – 18 pregnant women with antibodies from Denmark

18/1019 (1.8%) women with stored first trimester serum taken for Down’s screening at Copenhagen University Hospital Hvidovre between Feb 17 & Apr 23 2020, had SARS-CoV-2 antibodies (click here or deaa311). Half had had symptoms. None were hospitalised. One miscarried. Of 36 women who miscarried before Down’s screening, none had antibodies. The positive antibody women may overlap with those in study 299. Citation: la Cour Freiesleben N, Egerup P, Vauvert Römmelmayer Hviid K, Rosenbek Severinsen E, Kolte AM, Westergaard D, Fich Olsen L, Prætorius L, Zedeler A, Hellerung Christiansen AM, Reinhardt Nielsen J, Bang D, Berntsen S, Ollé-López J, Ingham A, Bello-Rodríguez J, Marie Storm D, Ethelberg-Findsen J, Hoffmann ER, Wilken-Jensen C, Stener Jørgensen F, Westh H, Løvendahl Jørgensen H, Nielsen HS. SARS-CoV-2 in first trimester pregnancy: a cohort study. Hum Reprod. 2020 Nov 4:deaa311. doi: 10.1093/humrep/deaa311. Epub ahead of print. PMID: 33145598.

Study 340 – 448 cases from Mexico

448 women in the open national database of COVID-19 from the Ministry of Health between February 28 & May 25, 2020, were pregnant (click here or jogh-10-020512). 137 were hospitalised, 14 admitted to ICU, 7 ventilated and 10 died. Some cases may overlap with those in studies 66 & 271. Citation: Ríos-Silva M, Murillo-Zamora E, Mendoza-Cano O, Trujillo X, Huerta M. COVID-19 mortality among pregnant women in Mexico: A retrospective cohort study. J Glob Health. 2020 Dec;10(2):020512. doi: 10.7189/jogh.10.020512. PMID: 33110595; PMCID: PMC7567444. [important]

4th November update – study 339 added

Study 339 – 65 cases from China

Using the Maternal and Child Health Information Management System of Wuhan, 65 women with Covid-19 delivering between Jan 13 & March 18 were identified and compared with 11,013 women without, or not tested for, Covid-19 (click here or s12916-020-01798-1). The paper was first submitted on 14 May. Despite six revisions the authors fail to make clear, and the referees & editors failed to notice, that most, if not all, of these cases will have been included in studies 1, 2, 6a, 8, 10, 11, 12, 13, 15, 34, 36, 39, 54, 55, 57, 59, 73, 75, 80, 108, 179, 183, 211, 220, 262b, 268, 280, 294, 305, & 329. Citation: Yang, R., Mei, H., Zheng, T. et al. Pregnant women with COVID-19 and risk of adverse birth outcomes and maternal-fetal vertical transmission: a population-based cohort study in Wuhan, China. BMC Med 18, 330 (2020). https://doi.org/10.1186/s12916-020-01798-1

3rd November update – studies 336 to 338 added

Study 338 – birth outcomes among 4,442 pregnancies from the US

5,252 women with laboratory-confirmed SARS-CoV-2 infection were reported from 16 jurisdictions within the Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET), during March 29–October 14, 2020 (click here or mm6944e2-H). 309 pregnancies were presumed ongoing, and 501 had missing outcomes. Among 4,442 women with known pregnancy outcomes there were 3,912 live births with known gestational age, 12.9% were preterm (<37 weeks).  Among 4,527 babies (incl. 79 twins and one set of triplets) 12 (0.3%) pregnancies miscarried before 20 weeks and there was 20 stillbirths (0.4%) after 20 weeks. Among 610 infants with reported SARS-CoV-2 test results, 16 were positive.  Citation: Woodworth KR, Olsen EO, Neelam V, et al. Birth and Infant Outcomes Following Laboratory-Confirmed SARS-CoV-2 Infection in Pregnancy — SET-NET, 16 Jurisdictions, March 29–October 14, 2020. MMWR Morb Mortal Wkly Rep. ePub: 2 November 2020. DOI: http://dx.doi.org/10.15585/mmwr.mm6944e2external icon [important]

Study 337 – 30,415 maternal outcomes from the US

Compared with nonpregnant women of the same age, pregnant women were more frequently admitted to ICU (10.5 versus 3.9 per 1,000 cases), ventilated (2.9 versus 1.1 per 1,000 cases), treated with ECMO (0.7 versus 0.3 per 1,000 cases) (click here or mm6944e3-H). 34/23,434 (1.5 per 1,000) symptomatic pregnant women died, compared with 447/386,028 (1.2 per 1,000) nonpregnant women. Citation: Zambrano LD, Ellington S, Strid P, et al. Update: Characteristics of Symptomatic Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status — United States, January 22–October 3, 2020. MMWR Morb Mortal Wkly Rep. ePub: 2 November 2020. DOI: http://dx.doi.org/10.15585/mmwr.mm6944e3external icon [important]

Study 336 – 5 women from Israel,

Vaginal swabs were tested from 35 women, aged 21-93 years with Covid-19 (click here or 1471-0528.16556). Two were positive. Five of the tested women were in the 3rd trimester of pregnancy, but none of them had a postive vaginal swab. From author affilitions the women were cared for in Lis Maternity Hospital, Tel Aviv, and may therefore be included in study 330. Citation: Schwartz, A., Yogev, Y., Zilberman, A., Alpern, S., Many, A., Yousovich, R. and Gamzu, R. (2020), Detection of SARS‐CoV‐2 in vaginal swabs of women with acute SARS‐CoV‐2 infection: a prospective study.. BJOG: An International Journal of Obstetrics & Gynaecology. Accepted Author Manuscript. doi:10.1111/1471-0528.16556

1st November update – studies 329 to 335 added

Study 335 – Case report from Italy

A woman with Covid-19 at 27 weeks required mechanical ventilation for over 4 weeks, latterly via tracheostomy, and was delivered by Caesarean section at 30 weeks (click here or ccr3.3426). She survived. The baby tested negative and survived. Both were cared for at Ospedali Riuniti Villa Sofia-Cervello, Palermo which has not previously reported cases. Citation: Donzelli, MIppolito, MCatalisano, G, et al. Prone positioning and convalescent plasma therapy in a critically ill pregnant woman with COVID‐19. Clin Case Rep. 2020001– 7https://doi.org/10.1002/ccr3.3426

Study 334 – seroprevalaence among pregnant women, UK

53/1000 (5.3%) of antenatal blood samples, in the Oxford region, between 14 April and 15 June 2020 were positive for SARS-CoV-2 IgG (click here or Lumley eurosurv-25-42-4). Citation: Lumley Sheila F , Eyre David W , McNaughton Anna L , Howarth Alison , Hoosdally Sarah , Hatch Stephanie B , Kavanagh James , Chau Kevin K , Downs Louise O , Cox Stuart , Dunn Laura , Justice Anita , Wareing Susan , Dingle Kate , Rudkin Justine , Auckland Kathryn , Fyfe Alexander , Bolton Jai , Paton Robert , Mentzer Alexander J, Jeffery Katie , Andersson Monique I , James Tim , Peto Tim E A , Marsden Brian D , Screaton Gavin , Cornall Richard J , Klenerman Paul , Ebner Daniel , Stuart David I , Crook Derrick W , Stoesser Nicole , Kennedy Stephen H , Thompson Craig , Gupta Sunetra , Matthews Philippa C ORCID icon. SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020. Euro Surveill. 2020;25(42):pii=2001721. https://doi.org/10.2807/1560-
7917.ES.2020.25.41.2001721 

Study 333 – 250 cases from Italy

In this updated series from Lombardy, of 250 pregnant women with either asymptomatic, non-severe, or severe SARS-CoV-2 up to June 18, 2020, nine were admitted to ICU but there were no maternal deaths (click here or ijgo.13435). Some cases were included in studies 32, 64, 114, 180, 188, 197 & 252. Citation: Di Martino, D., Chiaffarino, F., Patanè, L., Prefumo, F., Vergani, P., Ornaghi, S., Savasi, V., Spinillo, A., Cromi, A., D’Ambrosi, F., Tassis, B., Iurlaro, E., Parazzini, F. and Ferrazzi, E. (2020), Assessing risk factors for severe forms of COVID‐19 in a pregnant population: A clinical series from Lombardy, Italy. Int J Gynecol Obstet. Accepted Author Manuscript. doi:10.1002/ijgo.13435

Study 332 – Case report from Granada, West Indies

A woman with Covid-19 gave birth to an infected neonate (click here or Majachani AMCaseRep 925766). The mother had a past history of HIV infection. Both recovered. From author affiliations the unnamed hospital was probably St. George’s University General Hospital, which has not previously reported cases. Citation: Nicole Majachani, Jean Luc M. Francois, Ashen K. Fernando, Jamshed Zuberi. A Case of a Newborn Baby Girl Infected with SARS-CoV-2 Due to Transplacental Viral Transmission. Am J Case Rep 2020; 21:e925766 DOI: 10.12659/AJCR.925766. Available online: 2020-09-17

Study 331 – 180 cases from USA

Of these 180 women with Covid-19 in pregnancy, 7 required intensive care (click here or Janssen AJOG MFM). Three babies tested positive but none had illness consistent with COVID-19. The patients were probably cared for in the Northwell system hospitals in New York, so some have probably been reported in studies 162, 179, 289 & 315.  Citation: Janssen O, Thompson M, Milburn S, Green R, Wagner B, Bianco A, Stroustrup A, The Impact of Perinatal SARS-CoV2 Infection During the Peripartum Period, American Journal of Obstetrics & Gynecology MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100267.&nbsp;

Study 330 – 52 cases from 7 hospitals in Israel

Of 52 women with Covid-19 in pregnancy, one was critically ill, but no babies were infected (click here or Rottenstreich2020_Article_VaginalDeliveryInSARS-CoV-2-in). The seven hospitals are unnamed, but from author affiliations probably include Hadassah-Hebrew University Medical Center, Jerusalem: Sheba Medical Center, Tel-Aviv University, Tel-Hashomer; Mayenei Hayeshua Medical Center, Tel-Aviv University, Ramat Gan; Lis Maternity Hospital, Tel-Aviv; Meir Medical Center, Tel-Aviv University, Kfar Saba; and Ziv Medical Center, Safed. None of these hospitals have reported cases. Citation: Rottenstreich, A., Tsur, A., Braverman, N. et al. Vaginal delivery in SARS-CoV-2-infected pregnant women in Israel: a multicenter prospective analysis. Arch Gynecol Obstet (2020). https://doi.org/10.1007/s00404-020-05854-2

Study 329 – 60 cases from China

These cases (click here or fcimb-10-560899) delivered between January 24 & March 14, 2020 in the Maternity and Child Health Hospital in Wuhan, Hubei province have probabaly been reported many times. The MCH hospital is part of Huazhong University of Science and Technology Hospital grid.488485.d. Studies 8, 17, 30, 38, 54, 55 & 262b. Citation: Sun G, Zhang Y, Liao Q and Cheng Y (2020) Blood Test Results of Pregnant COVID-19 Patients: An Updated Case-Control Study. Front. Cell. Infect. Microbiol. 10:560899. doi: 10.3389/fcimb.2020.560899

31st October update – study 328 added

Study 328 – 154 cases from the Dominican Republic

Of 154 women with Covid-19, 15 developed cardiac injury (click here or Mercedes AJOG PIIS0002937820312060). Two died. The hospital is “an obstetric tertiary level hospital in Santo Domingo”. However none of the authors report an affiliation from that city, which contains more than one large maternity hospital.  Citation: Mercedes BR, Serwat A, Naffaa L, Ramirez N, Khalid F, Steward SB, Caro Feliz OG, Kassab M, Karout L, New-Onset myocardial injury in COVID-19 Pregnant Patients: A Case Series of 15 Patients, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.10.031

28th October – study 327 added

Study 327 – 40 cases of neonatal SARS-CoV-2 from a Spanish registry

A National Registry supported by the Spanish Society of Neonatology identified 40 neonates who tested positive for SARS-CoV-2 between 3 April & 18 May 2020 (click here or fped-08-580584) Citation: Fernández Colomer Belén, Sánchez-Luna Manuel, de Alba Romero Concepción, Alarcón Ana, Baña Souto Ana, Camba Longueira Fátima, Cernada María, Galve Pradell Zenaida, González López María, López Herrera M. Cruz, Ribes Bautista Carmen, Sánchez García Laura, Zamora Flores Elena, Pellicer Adelina, Alonso Díaz Clara, Herraiz Perea Cristina, Romero Ramírez Dolores Sabina, de las Cuevas Terán Isabel, Pescador Chamorro Isabel, Fernández Trisac José Luis, Arruza Gómez Luis, Cardo Fernández Luis Miguel, García García Mª Jesús, Nicolás López Marta, Hortelano López Miryam, Riaza Gómez Mónica, Hernández González Natalio, González Sánchez Raquel, Zambudio Sert Sílvia, Larrosa Capacés Susana, Matías del Pozo Vanesa. Neonatal Infection Due to SARS-CoV-2: An Epidemiological Study in Spain. Frontiers in Pediatrics. VOL 8. 2020. p 670. https://www.frontiersin.org/article/10.3389/fped.2020.580584. DOI 10.3389/fped.2020.580584

25th October – study 326 added

Study 326 – seroprevalence in Paris, France

Of women admitted to the delivery room at Antoine Be´clère Hospital maternity ward from 4th to 31st May, 20/249 (8%) were SARS-CoV-2 IgG positive (click here or journal.pone.0240782). 1/190 tested for nasopharyngeal SARS-CoV-2 RT-PCR was positive. She was asymptomatic and her baby tested negative. The period covered the final week of, and first three weeks post, lockdown. Citation: Mattern J, Vauloup-Fellous C, Zakaria H, Benachi A, Carrara J, Letourneau A, et al. (2020) Post lockdown COVID-19 seroprevalence and circulation at the time of delivery, France. PLoS ONE 15(10): e0240782. https://doi.org/10.1371/journal.pone.0240782.

24 October update – studies 319 to 325 added

Study 325 – Screening in Portugal

Click here. 11/184 (6.0%) of pregnant women screened for SARS-CoV-2 on admission in labour between 19th March and 4th May were positive. Two reported symptoms (click here or ). From author affiliations the hospital was Centro Hospitalar Universitário de São João, Porto. Citation: Figueiredo R, Tavares S, Moucho M, Ramalho C. Systematic screening for SARS-CoV-2 in pregnant women admitted for delivery in a Portuguese maternity. J Perinat Med. 2020 Oct 21:/j/jpme.ahead-of-print/jpm-2020-0387/jpm-2020-0387.xml. doi: 10.1515/jpm-2020-0387. Epub ahead of print. PMID: 33085639.

Study 324 – A case of neonatal SARS in Portugal

Full text not yet available (click here or ). From author affililations this was Hospital de São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Lisbon. Citation: Correia, Cátia R. MD*; Marçal, Mónica MD*; Vieira, Filipa MD*; Santos, Edmundo MD*; Novais, Cristina MD*; Maria, Ana Teresa MD*; Malveiro, Duarte MD*; Prior, Ana Rita MD*; Aguiar, Marta MD*; Salazar, Anabela MD*; Gouvêa Pinto, Constança MD*; Carvalho Rodrigues, Luís MD†; Pessanha, Maria Ana PhD†; Borges, Vítor PhD‡; Isidro, Joana MSc‡; Gomes, João Paulo PhD‡; Duarte, Sílvia MSc§; Vieira, Luís MSc§; Costa, Inês MSc¶; Alves, Maria João PhD‖; Calhau, Conceição PhD**; Guiomar, Raquel MSc¶; Tuna, Madalena Lopo MD* Congenital SARS-CoV-2 Infection in a Neonate With Severe Acute Respiratory Syndrome, The Pediatric Infectious Disease Journal: October 22, 2020 – Volume Online First – Issue –
doi: 10.1097/INF.0000000000002941 

Study 323 – Two mothers treated with ECMO in USA

Two women with Covid-19 required treatment with ECMO (click here or s-0040-1718694). Both mothers and babies survived. From author affiliations they were cared for in the University of California, Los Angeles. The hospital is not named.  Citation: K. Marie Douglass, Katie M. Strobel, Michael Richley, Thalia Mok  , Annabelle de St Maurice, Viviana Fajardo, Andrew T. Young, Rashmi Rao, Lydia Lee, Peyman Benharash, Alison Chu, Yalda Afshar. Maternal-Neonatal Dyad Outcomes of Maternal COVID-19 Requiring Extracorporeal Membrane Support: A Case Series Am J Perinatol. DOI: 10.1055/s-0040-1718694

Study 322 – 60 cases from Oman

Sixty women with Covid-19 were cared for at The Royal Hospital, Muscat, from March 24 to July 31, 2020 (click here or ijgo.13427). Seven required ITU care of whom one was critically ill. No mothers died. There were four miscarriages, one stillbirth and eight pregnancies ongoing. The remainder of the babies survived. All four tested neonates were negative. Citation: Santhosh, J., Al Salmani, M., Khamis, F., Al Ubaidani, S.A. and Al‐Zakwani, I. (2020), Clinical characteristics of COVID‐19 in pregnant women: A retrospective descriptive single‐center study from a tertiary hospital in Muscat, Oman. International Journal of Gynecology & Obstetrics. Accepted Author Manuscript. doi:10.1002/ijgo.13427

Study 321 – Four cases from Iran

Four pregnant women contracted Covid -19 (click here or Iran case series). All four recovered. One was postnatal, one delivered vaginally and two remained undelivered. They were cared for in Shahid Mostafa Khomeini Hospital in Ilam which has not previously reported cases. Citation: Gheysarzadeh A, Sadeghifard N, Safari M, Rashidian T, Mohammadyari E, Tavan H, Report of four pregnant women getting COVID-19 in Ilam, Iran: Case Series, New Microbes and New Infections, https://doi.org/10.1016/j.nmni.2020.100783.&nbsp;

Study 320 – Case report from USA

A woman with Covid-19 at 36 weeks required 6 days ventilation and delivery by Caesarean (click here or 8889487). She survived, but at the time of the report remained in an inpatient rehabilitation facility. The baby tested negative. From author affiliations she was likely cared for in the Einstein Medical Center, Philadelphia which has not previously reported cases. Citation: Jerald Pelayo ,Gabriella Pugliese, Grace Salacup, Eduardo Quintero, Adeeb Khalifeh, David Jaspan, and Bhavna Sharma. Severe COVID-19 in Third Trimester Pregnancy: Multidisciplinary Approach. Case reports in Critical Care. Volume 2020 |Article ID 8889487 | https://doi.org/10.1155/2020/8889487

Study 319 – No cases in 3 hospitals in Australia

No positive test results among 350 pregnant women from three hospitals in Melbourne over the two-week period 6th to 19th May 2020 (click here or Rolnik 1-s2.0-S1871519220303553-main). This period was after the first wave had subsided. Citation: D.L. Rolnik, T.M. Korman, A. Rindt et al., Coronavirus testing in women attending antenatal care, Women Birth, https://doi.org/10.1016/j.wombi.2020.09.024&nbsp;

20th October update – study 318 added

Study 318 – Case report from Chizhou, Anhui Province, China

A woman contracted Covid-19 on Jan 6th, six months after delivery while still breastfeeding ((click here or 15010_2020_Article_1532). Breastfeeding was stopped and the infant artificially fed at home. The infant’s infection status and outcome were not reported. The mother recovered. Citation: Liu X, Zhou L, Zhu Y. Report on a lactating patient with COVID-19 [published online ahead of print, 2020 Oct 9]. Infection. 2020;1-5. doi:10.1007/s15010-020-01532-2

19th October update – study 317 added

Study 317 – 101 neonates from USA

Of 101 neonates born to 100 mothers positive for SARS-CoV-2 from March 13 to April 24, 2020, two had borderline results and the rest tested negative. No baby had clinical disease (click here or jamapediatrics_dumitriu_2020_oi_200070_1601920765.25034). From author affiliations Columbia University Irving Medical Center. Fourteen babies were reported in study 27. Citation: Dumitriu D, Emeruwa UN, Hanft E, et al. Outcomes of Neonates Born to Mothers With Severe Acute Respiratory Syndrome Coronavirus 2 Infection at a Large Medical Center in New York City. JAMA Pediatr. Published online October 12, 2020. doi:10.1001/jamapediatrics.2020.4298

18th October update – studies 315 and 316 added

Study 316  – Case report from Japan.

A woman with Covid-19 was delivered by caesarean section on April 2nd (click here or jog.14393). This was the first birth to a woman with Covid-19 in Japan. Mother and baby survived. The baby was not infected. They were cared for in the Center for Perinatal, Pediatric and Developmental Medicine, Kitasato University Hospital which has not previously reported cases. Citation: Mochizuki, J., Nakamura, M., Iwahata, S., Nishijima, J., Ito, T., Wada, T., Takayama, Y. and Unno, N. (2020), First report in Japan of a delivery of a woman with the 2019 novel coronavirus disease. J. Obstet. Gynaecol. Res.. doi:10.1111/jog.14393

Study 315 – 31 severe cases from New York

Of 31 pregnant women with severe or critical disease, four had abnormal cardiac biomarkers, of whom two died (click here or PIIS0002937820311881). The women were cared for in the Northwell health system so may have been included in studies 162, 179 and 289. Citation: PACHTMAN SHETTY SL, MEIROWITZ N, BLITZ MJ, GADOMSKI T, WEINBERG CR, Myocardial injury associated with coronavirus disease 2019 in pregnancy, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.10.014. &nbsp;

17 October update – studies 311 to 314 added

Study 314 – 141 cases from USA

Of 141 women with Covid-19 in pregnancy, one died (click here or PIIS2589933320302147 (1)). Of 76 live births, no babies were affected. They were cared for in Yale New Haven, Bridgeport, and Greenwich hospitals. One woman, who had a 22 week termination for severe pre-eclampsia, was reported in study 155. Some may also have been included in study 132. Citation: GRECHUKHINA O, GREENBERG V, LUNDSBERG LS, DESHMUKH U, CATE J, LIPKIND HS, CAMPBELL KH, PETTKER CM, KOHARI KS, REDDY UM, Coronavirus Disease 2019 (COVID-19) pregnancy outcomes in a racially and ethnically diverse population, American Journal of Obstetrics & Gynecology MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100246.

Study 313 – Case report from Mumbai, India

In this MedRxiv preprint, an asymptomatic woman tested positive for SARS-CoV-2 at 8 weeks gestation. At 13 weeks the fetus had died (click here or 2020.08.18.20177121v1.full). The authors detected virus in the placenta and argue the fetal demise was due to congenital transmission of SARS-CoV-2. Citation: Prajakta Shende, Pradip Gaikwad, Manisha Gandhewar, Pawankumar Ukey, Anshul Bhide, Vainav Patel, Sharad Bhagat, Vikrant Bhor, Smita Mahale, Rahul Gajbhiye, Deepak Modi Persistence of SARS-CoV-2 in the first trimester placenta leading to vertical transmission and fetal demise from an asymptomatic mother. medRxiv 2020.08.18.20177121; doi: https://doi.org/10.1101/2020.08.18.20177121. 29 December update. Published in Human Reproduction (click here). Citation: Shende P, Gaikwad P, Gandhewar M, Ukey P, Bhide A, Patel V, Bhagat S, Bhor V, Mahale S, Gajbhiye R, Modi D. Persistence of SARS-CoV-2 in the first trimester placenta leading to transplacental transmission and fetal demise from an asymptomatic mother. Hum Reprod. 2020 Dec 21:deaa367. doi: 10.1093/humrep/deaa367. Epub ahead of print. PMID: 33346816.

Study 312 – analysis of a range of specimens from 31 affected pregnancies in Italy

31 pregnancies with SARS-CoV-2 (click here or s41467-020-18933-4). From author affiliations the patients were probably cared for in Milan. Citation: Fenizia, C., Biasin, M., Cetin, I. et al. Analysis of SARS-CoV-2 vertical transmission during pregnancy. Nat Commun 11, 5128 (2020). https://doi.org/10.1038/s41467-020-18933-4

Study 311 – 21 placentas from St Louis, USA

No differences were seen between 21 placentas from SARS-CoV-2 positive pregnancies and 20 control ones (click here or Histopathology of Third Trimester Placenta from SARS CoV 2 Positive Women). The hospitals are not reported. Citation: Mai He, Priya Skaria, Kasey Kreutz, Ling Chen, Ian S. Hagemann, Ebony B. Carter, Indira U. Mysorekar, D. Michael Nelson, John Pfeifer & Louis P. Dehner (2020) Histopathology of Third Trimester Placenta from SARS-CoV-2-Positive Women, Fetal and Pediatric Pathology, DOI: 10.1080/15513815.2020.1828517

13 October update – studies 309 and 310 added

Study 310 – 86 pregnant women treated with remdesivir

Of the first 86 pregnant, or recently pregnant, women with severe Covid-19 (O2 satuation <=94%), treated with compassionate use remdesivir (all outside a trial) between March 21, & April 22nd 2020, 63 were admitted to ICU, 45 required ventilation and one ECMO (click here or ciaa1466). One woman died. At 28-day follow-up seven women were still being ventilated (appendix Fig 2 ciaa1466_suppl_supplementary_materials_1 (1)).  Among 45 deliveries there was one 17 weeks miscarriage but otherwise no babies died. Four women were treated in Spain, two in Switzerland and one each in Italy and the UK. The rest were from the United States. Many have presumably been included in other reports. Citation: Richard M Burwick, Sigal Yawetz, Kathryn E Stephenson, Ai-Ris Y Collier, Pritha Sen, Brian G Blackburn, E Milunka Kojic, Adi Hirshberg, Jose F Suarez, Magdalena E Sobieszczyk, Kristen M Marks, Shawn Mazur, Cecilia Big, Oriol Manuel, Gregory Morlin, Suzanne J Rose, Mariam Naqvi, Ilona T Goldfarb, Adam DeZure, Laura Telep, Susanna K Tan, Yang Zhao, Tom Hahambis, Jason Hindman, Anand P Chokkalingam, Christoph Carter, Moupali Das, Anu O Osinusi, Diana M Brainard, Tilly A Varughese, Olga Kovalenko, Matthew D Sims, Samit Desai, Geeta Swamy, Jeanne S Sheffield, Rebecca Zash, William R Short, Compassionate Use of Remdesivir in Pregnant Women with Severe Covid-19, Clinical Infectious Diseases, , ciaa1466, https://doi.org/10.1093/cid/ciaa1466

Study 309 – 2,475 pregnant women with Covid-19 from Brazil

Among 2,475 women identified through an acute respiratory distress register, 494 were admitted to ITU, 242 underwent invasive ventilation and 204 died (click here or ijgo.13407). Among the women who died, 8 (6%) had not reached hospital, 81 (40%) had not been admitted to intensive care, and 52 (26%) had no access to any respiratory support before dying. These are updated figures from studies 182, 248 & 249. Citation: Menezes, M.O., Takemoto, M.L., Nakamura‐Pereira, M., Katz, L., Amorim, M.M., Salgado, H.O., Melo, A., Diniz, C.S., de Sousa, L.A., Magalhaes, C.G., Knobel, R., Andreucci, C.B. and (2020), Risk factors for adverse outcomes among pregnant and postpartum women with acute respiratory distress syndrome due to COVID‐19 in Brazil. Int J Gynecol Obstet. Accepted Author Manuscript. doi:10.1002/ijgo.13407  [important]

12 October update – studies 303 to 308 added.  Study 167 publication updated.

Study 308 – Case report from Korea

One case report of Covid-19 in pregnancy plus 12 further cases mentioned in the final pragraph (click here or ogs-20106). All cared for at Daegu Fatima Hospital or Daegu Dongsan Hospital and likely overlap with those in studies 22 & 143.  Citation: Jin-Gon Bae , Jin-Kyeong Ha, Myoung Kwon, Hak-Youle Park, Won-Joon Seong, Seong-Yeon Hong. A case of delivery of a pregnant woman with COVID-19 infection in Daegu, Korea. Obstet Gynecol Sci > Epub ahead of print  Case Report DOI: https://doi.org/10.5468/ogs.20106 [Epub ahead of print] Published online October 5, 2020.

Study 307 – 257 cases from Europe and other continents

These cases (click here or PIIS0301211520306400) probably overlap considerably with those reported in study 278. Citation: Di Mascio D, D’Antonio F, Perinatal mortality and morbidity of SARS-COV-2 infection during pregnancy in European countries: findings from an international study, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.10.009

Study 306 – Neonatal death in Ilam province, Iran

The mother had Covid-19 (click here or 13256_2020_Article_2519). The baby, delivered by elective caesarean at 39 weeks, had normal Apgar scores but collapsed soon after birth and died. Maternal SARS-CoV-2 swabs were positive, and baby swabs negative. The birth was at Zagros Hospital and the baby was later transferred to Ayatollah Taleghani Hospital, both in Ivan City, and neither of which have previously reported caes. Citation: Rashidian, T., Sharifi, N., Fathnezhad-Kazemi, A. et al. Death of a neonate with suspected coronavirus disease 2019 born to a mother with coronavirus disease 2019 in Iran: a case report. J Med Case Reports 14, 186 (2020). https://doi.org/10.1186/s13256-020-02519-1

Study 305 – Two cases from Wuhan, China

These two women with Covid-19 in pregnancy have probably been reported already (click here or s12884-020-03281-4). Citation: Cao, D., Chen, M., Peng, M. et al. Vaginal delivery in women with COVID-19: report of two cases. BMC Pregnancy Childbirth 20, 580 (2020). https://doi.org/10.1186/s12884-020-03281-4

Study 304 – 32 pregnant women admitted to ITU in the USA

Thirty two pregnant women with Covid-19 were admitted to ITU in multiple US hospitals (click here or rccm.202006-2182le). Citation: Sarah Rae Easter, Shruti Gupta, Samantha K. Brenner, David E. Leaf Outcomes of Critically Ill Pregnant Women with COVID-19 in the United States. American Journal of Respiratory and Critical Care Medicine Published Online: October 07, 2020 https://doi.org/10.1164/rccm.202006-2182LE

Study 303 – Case report from Turkey

This case report from (judging by author affiliations) Recep Tayyip Erdoğan University School of Medicine, Rize (click here or 354-356) may have been reported in studies 244 and 277Citation: Özçelik N, Özdemir S, Gürlek B, Yıldız İE. COVID-19 Pregnant Patient Management with a Case of COVID-19 Patient with An Uncomplicated Delivery. Turk Thorac J. 2020 Sep;21(5):354-356. doi: 10.5152/TurkThoracJ.2020.20135. Epub 2020 Sep 1. PMID: 33031729.

11 October update – study 302 added

Study 302 – Two cases of repeat SARS-CoV-2 positivity in pregnancy from Italy

A pregnant women who had recovered from mild Covid-19 in March 2020 at 24 weeks, retested positive when she gave birth in July at 41 weeks. Another asymptomatic women with SARS-CoV-2 in April at 32 weeks gestation, who had later tested negative, tested positive again at birth in June (click here or 1471-0528.16362). From author affiliations both cases were probably cared for in Brescia which means they were likely included in studies 32, 64 & 252. Citation: Zanardini, C., Saccani, B., Franceschetti, l., Zatti, S., Sartori, E. and Prefumo, F. (2020), Retest positive for SARS‐CoV‐2 RNA of recovered pregnant women with COVID‐19. Ultrasound Obstet Gynecol. Accepted Author Manuscript. doi:10.1002/uog.23144

10 October update – study 301 added

Study 301 – 736 women in the US PRIORITY study

The clinical features of 736 pregnant women with Covid-19 (594 SARS-CoV-2 positive), recruited through social media in the PRIORITY study, are reported (click here or 1471-0528.16362). They will overlap with study 281 and many other US reports. Citation: Afshar, Yalda MD, PhD; Gaw, Stephanie L. MD, PhD; Flaherman, Valerie J. MD; Chambers, Brittany D. PhD, MPH; Krakow, Deborah MD; Berghella, Vincenzo MD; Shamshirsaz, Alireza A. MD; Boatin, Adeline A. MD, MPH; Aldrovandi, Grace MD; Greiner, Andrea MD; Riley, Laura MD; Boscardin, W. John PhD; Jamieson, Denise J. MD; Jacoby, Vanessa L. MD, MAS, on behalf of the Pregnancy CoRonavIrus Outcomes RegIsTrY (PRIORITY) Study Clinical Presentation of Coronavirus Disease 2019 (COVID-19) in Pregnant and Recently Pregnant People, Obstetrics & Gynecology: October 07, 2020 – Volume Latest Articles – Issue – 10.1097/AOG.0000000000004178 doi: 10.1097/AOG.0000000000004178

9 October update – study 300 added

Study 300 – 26 cases from Dublin, Ireland

26 women had SARS-CoV-2 detected during pregnancy by PCR in the Rotunda Hospital between 1st March & 1st July 2020 (click here or Infants-Born-to-Mothers-with-COVID-19-During-Pregnancy-The-First-Four-Months-of-the-Pandemic). Maternal survival was not reported but, by implication, was good. All infants survived and none were infected. These case are probably included in study 284. Citation: C. Murphy, D. O’Reilly, N. McCallion, R. Drew, W. Ferguson. Infants Born to Mothers with COVID-19 During Pregnancy: The First Four Months of the Pandemic Ir Med J; Vol 113; No. 9; P193

8 October update – study 299 added

Study 299 – 29 women with anti SARS-CoV-2 antibodies from Denmark

Of the 29 women reported in this Medxiv preprint, 15 had previously had Covid-19 symptoms, but none had a positive swab (click here or 2020.09.14.20191106v1.full). They were cared for at Copenhagen University Hospital, Hvidovre, which has not previously reported cases. Citation; Pia Egerup, Line Fich Olsen, Ann-Marie Hellerung Christiansen, David Westergaard, Elin Rosenbek Severinsen, Kathrine Vauvert Roemmelmayer Hviid, Astrid Marie Kolte, Amalie Dyhrberg Boje, Marie-Louise Mathilde Friis Bertelsen, Lisbeth Praetorius, Anne Zedeler, Josefine Reinhardt Nielsen, Didi Bang, Sine Berntsen, Jeppe Ethelberg-Findsen, Ditte Marie Storm, Judith Bello-Rodriguez, Andreas Ingham, Joaquim Olle-Lopez, Eva Hoffmann, Charlotte Wilken-Jensen, Lone Krebs, Finn Stener Joergensen, Henrik Torkil Westh, Henrik Lovendahl Jorgensen, Nina la Cour Freiesleben, Henriette Svarre Nielsen medRxiv 2020.09.14.20191106; doi: https://doi.org/10.1101/2020.09.14.20191106

5 October update – studies 292 to 298 added

Study 298 – 67 cases from Sweden

The authors claim that these 67 pregnant women with SARS-CoV-2 comprise all those cared for in the Stockholm region between March 19 & April 26, 2020 (click here or aogs.14006). Four women were admitted to intensive care but none died. Three babies were infected. Two babies died. From author affliliations the unnamed hospitals probably include Karolinska, Södersjukhuset (Southern), Danderyd, and Södertälje hospitals. The series likely includes some women reported in studies 20, 88, and 282. Study 282 reported 156 women with SARS-Cov-2 admitted in labour to the Karolinska alone, albeit over a longer time period March 25 to July 24 (study 282). Citation: Remaeus, K., Savchenko, J., Brismar Wendel, S., Gidlöf, S.B., Graner, S., Jones, E., Molin, J., Saltvedt, S., Wallström, T. and Pettersson, K. (2020), Characteristics and short‐term obstetric outcomes in a case series of 67 women tested positive for SARS‐CoV‐2 in Stockholm, Sweden. Acta Obstet Gynecol Scand. Accepted Author Manuscript. doi:10.1111/aogs.14006

Study 297 – anti SARS-CoV-2 IgA in breastmilk within 72 hr of birth

A woman with a clinical diagnosis of Covid-19, but with negative PCR tests, delivered by Caesarean at 37 weeks (click here or 0890334420960433). Anti SARS-CoV-2 IgA was detected in breast milk soon after birth. The baby was not infected. From author affiliations the hospital was probably Municipal Universitário de São Bernardo do Campo, Brazil, which has not previously reported cases. Citation: Lebrão CW, Cruz MN, Silva MH da, et al. Early Identification of IgA Anti-SARSCoV-2 in Milk of Mother With COVID-19 Infection. Journal of Human Lactation. September 2020. doi:10.1177/0890334420960433

Study 296 – Case report from USA

A woman wih Covid-19 developed pre-eclampsia at 34 weeks (click here or main). Both her and the baby recovered. From author affiliations the hospital was probably Maine Medical Center, Portland, Maine, which has not previously reported cases. Citation: J.N. Hansen, J. Hine and T.D. Strout, COVID-19 and preeclampsia with severe features at 34-weeks gestation, American Journal of Emergency Medicine, https://doi.org/10.1016/j.ajem.2020.06.052

Study 295 – Takotsubo cardiomyopathy in pregnancy & SARS-CoV-2

The first report of Takotsubo cardiomyopathy in pregnancy in association with SARS-CoV-2 infection (click here or e239104.full). The mother was delivered by caesarean and recovered. Baby outcomes were not reported. The hospital was probably Gauhati Medical College and Hospital, Guwahati, India, which has not previously reported cases. Citation: Bhattacharyya PJAttri PKFarooqui W. Takotsubo cardiomyopathy in early term pregnancy: a rare cardiac complication of SARS-CoV-2 infection.

Study 294 – 16 women with SARS-CoV-2 infection from China

16 pregnant women with SARS-CoV-2 infection (click here or Zhou2020_Article_TheMetabolicAndImmunologicalCh). From author affiliations and ethics committee review the hospital was probably Renmin Hospital of Wuhan University grid.412632.0, which means the cases probably overlap with those in studies 6a, 10, 12, 36, 37, and 40. Citation: Zhou, J., Wang, Y., Zhao, J. et al. The metabolic and immunological characteristics of pregnant women with COVID-19 and their neonates. Eur J Clin Microbiol Infect Dis (2020). https://doi.org/10.1007/s10096-020-04033-0

Study 293 – Infected triplets from Oman

All three triplets born by Caesarean at 32 weeks to a woman with Covid-19 were infected (click here or IS_VERTICAL_TRANSMISSION_OF_SARS_CoV_2_INFECTION.96038). They all thrived. The woman was cared for at Khoula Hospital, Muscat, which has not previously reported cases. Citation: Alwardi, Talal Hamood; Ramdas, Vidya; Al Yahmadi, Mohammed; Al Aisari, Salima; Bhandari, Satish; Saif Al Hashami, Hilal; Al Jabri, Amal; Manikoth, Prakash; Malviya, Manoj. IS VERTICAL TRANSMISSION OF SARS-CoV-2 INFECTION POSSIBLE IN PRETERM TRIPLET PREGNANCY? A CASE SERIES, The Pediatric Infectious Disease Journal: September 25, 2020 – Volume Online First – Issue – doi: 10.1097/INF.0000000000002926 

Study 292 – Blood loss at birth among 53 women in USA

The blood loss at birth among 53 women with Covid 19 was no different from women without the disease (click here or s-0040-1718403). Women were cared for in Boston Medical Center which has not previously reported cases. Citation: Wang MJ, Schapero M, Iverson R, Yarrington CD. Obstetric Hemorrhage Risk Associated with Novel COVID-19 Diagnosis from a Single-Institution Cohort in the United States. Am J Perinatol. 2020 Sep 29. doi: 10.1055/s-0040-1718403. Epub ahead of print. PMID: 32992351.

28 September update – study 291 added

Study 291 – Spanish registry of Covid-19 screening in asymptomatic pregnant women

By May 31st 2020, of 16,308 pregnant women screened, 338 (2.1%) had tested positive (click here or RS94C_202009092). Testing was done in 100 maternity hospitals listed in Table 2. This is a different registry from study 264b, which only covered 45 hospitals. However the hospitals, time period and presumably cases overlap.  Spanish with English abstract. Citation: Encinas Pardilla MB, Caño Aguilar Á, Marcos Puig B, Sanz Lorenzana A, Rodríguez de la Torre I, Hernando López de la Manzanara P, Fernández Bernardo A, Martínez Pérez Ó. Registro español de cribado de Covid-19 en gestantes asintomáticas. Rev Esp Salud Pública. 2020; 94: 18 de septiembre e202009092

27 September update – studies 284-290 added. I’ve also noticed ten duplicate numbers, studies 257 to 266 & renumbered the later ones as 257b to 266b

Study 290 – 25 symptomatic women in USA

25/532 (4.7%) women admitted for an obstetric procedure were asymptomatic but positive for SARS-CoV-2 at Barnes-Jewish Hospital in St Louis, Missouri from May 28 – July 22 (click here or PIIS0002937820311029). This series will not include the severely ill woman in study 69, but probably includes some in study 259. Citation: KELLY JC, RAGHURAMAN N, PALANISAMY A, STOUT MJ, CARTER EB, Pre-procedural asymptomatic COVID-19 in obstetric and surgical units, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.09.023.

Study 289 – seroprevalence during labour in New York State

269/1671 (16%) women were seropositive in labour (click here or Haizler-Cohen PIIS0002937820311017). They delivered in 7 hospitals in the Northwell Health system so probably were included in studies 162 and 179. Citation: HAIZLER-COHEN L, DAVIDOV A, BLITZ MJ, FRUHMAN G, SARS-CoV-2 Antibodies in Pregnant Women Admitted to Labor and Delivery, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.09.022.

Study 288 – serological testing among pregnant women in Estonia

The SARS-CoV-2 seroprevalemce was reported to be nearly five time higher than the rate of PCR positivity, and also 10 times lower than the rate of seropositivity in the general population of Spain (sic) (click here or aogs.13995) Citation: Veerus, P., Salumets, A., Naaber, P., Krjutškov, K., Tilk, K., Laanpere, M. and Uusküla, A. (2020), Seroprevalence of SARS‐CoV‐2 antibodies among p