Skip to content

Wild swimming in the Trent gravel pits

November 30, 2020

Sand and gravel has been quarried along the Trent for hundreds of years. The two official swimming lakes, Colwick Park (click here) and the Notts County Sailing Club lake at Hoveringham (click here or here for details) will suit many. But organised wild swimming? Not me.

Some lakes are inaccessible, or too closely guarded by their owners, but a few are perfect for a discreet dip. For swimming spots on the river click here.

9 Sept 2021 update – No swimming in Bleasby Lake

Hoveringham

Three lakes run alongside the railway line here. The smaller ones at either end are heavily  fished – no swimming. But the middle and largest, Railway Lake, is perfect. A sailing, canoeing & windsurfing club has put up all sorts of entry barriers, and their groundsman believes the whole lake is “no swimming”, so be discreet.

     

Enter by the path at Thurgaton station, but avoid the main footpath along the railway line. It’s over a mile before you can cross the ditch separating you from the lake.  Instead follow the permissive path signs, through an unlocked gate and along the north shore. The further you go, the more private it gets.

      

The best spots are where the trees give way to grass and reeds.

Lovely clean gravel beds. No weeds. Just me and the dragon flies.

Gunthorpe

The Gunthorpe lakes are all owned by angling clubs, who fish all year, and don’t like swimmers. I swam in Dollar Lake, the largest one adjacent to the river. If you walk in from the river bank on a quiet day, there no fences, and the fishermen tend to drive in from the opposite direction.

Bleasby

Bleasby Lake, at the end of Sycamore Lane, near the sawmill, is the only swimmable lake in Bleasby. There’s usually a few fishermen, but it’s rarely crowded, and they’ve never objected to me swimming. Loads of good access points. Weedy in parts.

Update 9 September 2021 – Swimming is not allowed in the fishing pond at the end of Sycamore Lane. See comment from Ruth Dyson below.

Jubilee Ponds would be perfect, and they’re accessible on foot down Borrow Bread Lane, but sadly, “No swimming”.

         

Gibsmere lake is also private fishing only – “No swimming”.  But don’t despair. There’s a couple of good spots on the Trent at Hazleton (click here).

Newark/South Muskham

There are many flooded pits between Newark and South Muskham, mostly around the sugar factory. But they’re all fishing lakes, or inaccessible, or both.

North Muskham

North Muskham Lake Nature Reserve (click here) is “no swimming”.  But walk north (downstream) from The Muskham Ferry pub (click here), past the fenced-off Nature Reserve lake. The second lake is set back behind grassland and invisible from the path, but the third is adjacent to the path with easy access. An idyllic spot.

    

Cromwell

You can swim in the river (click here) but the local gravel pit is still being worked by Tarmac – definitely no swimming!

Jim Thornton

Women’s Work

October 26, 2020

Two poems by UA Fanthorpe

      

Degas painted dozens of “La Repasseuse” Woman Ironing pictures. The one Fanthorpe refers to (right above) is in the Walker Art Gallery in Liverpool. It’s the last in a series of three of this particular pose. The George Bernard Shaw quote is from the play Man & Superman.

Woman Ironing

I thought I knew what was coming when he said,
He wanted to do my likeness at the ironing.
I live in the city, people tell you things. Me looking at him,
It would be, across the ironing board, my hair and my eyes
In a good light, and something a bit off the shoulder

But it wasn’t. He rushed around drawing curtains
Made it hard to iron. O yes, I had to keep ironing.
He need to see the strength, he said. Kept on
About my dynamic right shoulder, then left it out
Though you can see where he ought to have put it.

Come on, what’s-your-name, he kept saying,
Show us that muscle power! That’s what I’m after.
I might’ve been an engine, not a person
No, I didn’t take to him, I’m used to rudeness,
But he was making such a sketch of me.

If someone’s paying you, it isn’t easy
To speak your mind. Still, Sir, I said,
I really don’t want to see my hair like that,
all scraped back, like a hot person’s hair,
And anyone can tell that under my arms I’m sweating.

Hair? Sweat? That’s how it is when you iron,
Says he. You’re not here to tell me what to do.
I’ll make you permanent, the way you look
When you’re ironing. O yes, he says, I’ll show you
The way you look when no one’s watching.

UA Fanthorpe

Mother Scrubbing the Floor

She had a dancer’s feet, elegant, witty.
We had our father’s, maverick spreaders of dirt.

Dirt from London, dirt from Kent
Mud, dust, grass, droppings, wetness, things,
Dirt barefaced, dirt stinking, dirt invisible.

Whatever it was, she was ready:
The rubber kneeler, clanking galvanised bucket,
The Lifebuoy, the hard hot water.

Let me! we’d say, meaning Hate to see you do this.
Too old. Too resentful. Besides, you’ll blame us
That you had to do it.

She never yielded. We couldn’t do it right,
Lacking her hatred of filth, her fine strong hands.

Don’t want you to do this, she said. Don’t want you to have to.
Just remember this: love isn’t sex.
But the dreary things you do for the people you love.
And ‘Home is the girl’s prison,
The woman’s workhouse.’ Not me; Shaw.

I do remember. I stand where she knelt.

UA Fanthorpe

Indirect effects of the Covid-19 pandemic on pregnancy

October 8, 2020

Primary sources

Ripe-tomato.org has been collecting primary scientific (click here) & newspaper reports (click here) of Covid-19 or SARS-CoV-2 infection in pregnancy since early in the pandemic (click here for our Covid-19 in pregnancy navigation page).

Here we (Jim Thornton, Keelin O’Donoghue and Kate Walker) collect primary scientific reports of the indirect effects of the pandemic on pregnancy.  As usual facts but no comments. For convenience we list papers in roughly reverse order, newest first. We will update regularly.

Clarification added 1 October 2021 – We exclude studies of the effect of the pandemic on psychological scores in pregnant women, but include studies reporting effects on mental health events. Anxiety and depression scores are out. Suicide and suicide attempts are in.

Update 7 April – paper 126 added

Paper 126 – fewer iatrogenic preterm births in USA

A decline in pre-term birth post-lockdown driven primarily by births by Cesarean or induced (click here or paper). Citation: Dench D, Joyce T, Minkoff H. United States Preterm Birth Rate and COVID-19. Pediatrics. 2022;149(5):e2021055495

Update 12 February – papers 124 and 125 added

Paper 125 – no effect of lockdown in Bangladesh

Data from the Rajbari district, collected by the International Centre for Diarrhoeal Disease Research (click here or paper). Citation: Mhajabin S, Hossain AT, Nusrat N, Jabeen S, Ameen S, Banik G, Tahsina T, Ahmed A, Sadeq-Ur Rahman Q, Gurley ES, Bari S, Chowdhury AI, Arifeen SE, Mehta R, Rahman AE. Indirect effects of the early phase of the COVID-19 pandemic on the coverage of essential maternal and newborn health services in a rural subdistrict in Bangladesh: results from a cross-sectional household survey. BMJ Open. 2022 Feb 3;12(2):e056951. doi: 10.1136/bmjopen-2021-056951. PMID: 35115357; PMCID: PMC8814430.

Paper 124 – Experience from Africa

From Guinea, Nigeria, Tanzania, and Uganda (click here or paper). Citation: Semaan A, Banke-Thomas A, Amongin D, Babah O, Dioubate N, Kikula A, Nakubulwa S, Ogein O, Adroma M, Anzo Adiga W, Diallo A, Diallo L, Cellou Diallo M, Maomou C, Mtinangi N, Sy T, Delvaux T, Afolabi BB, Delamou A, Nakimuli A, Pembe AB, Benova L. ‘We are not going to shut down, because we cannot postpone pregnancy’: a mixed-methods study of the provision of maternal healthcare in six referral maternity wards in four sub-Saharan African countries during the COVID-19 pandemic. BMJ Glob Health. 2022 Feb;7(2):e008063. doi: 10.1136/bmjgh-2021-008063. PMID: 35144921.

Update 10 February – paper 123 added (HT Vivienne Souter)

Paper 123 – no major effects in USA

Data from 15 hospitals in the Pacific Northwest from 2017 to 2020 (click here or paper). Citation: Riley T, Nethery E, Chung EK, Souter V. Impact of the COVID-19 pandemic on perinatal care and outcomes in the United States: An interrupted time series analysis. Birth. 2021 Dec 26. doi: 10.1111/birt.12606. Epub ahead of print. PMID: 34957595.

Update 22 January – papers 121 and 122 added

Paper 122 – worse outcomes for TTTS during pandemic in Mexico

Twin pregnancies complicated by twin to twin transfusion syndrome (TTTS) referred to the Fetal Medicine and Surgery Center, Queretaro (click here or paper). Citation: López-Briones H, Villalobos-Gómez R, Chávez-González E, Martínez-Rodríguez M, Helue-Mena A, Gámez-Varela A, Cruz-Martinez R. Twin-to-twin transfusion syndrome and coronavirus disease 2019: Impact on diagnosis, referral, eligibility for fetoscopic laser therapy and outcomes. AJOG Glob Rep. 2022 Jan 13:100040. doi: 10.1016/j.xagr.2021.100040. Epub ahead of print. PMID: 35039807; PMCID: PMC8755450.

Paper 121 – No major effects in UK

From author affiliations data from St. Mary’s Hospital in Manchester (click here or paper). Citation: Wilkinson M, Johnstone ED, Simcox LE, Myers JE. The impact of COVID-19 on pregnancy outcomes in a diverse cohort in England. Sci Rep. 2022 Jan 18;12(1):942. doi: 10.1038/s41598-022-04898-5. PMID: 35042979; PMCID: PMC8766432.

Update 11 January – paper 120 added

Paper 120 – No major effects in UK

From the Hospital Episode Statistics database (click here or paper). Citation: Gurol-Urganci I, Waite L, Webster K, Jardine J, Carroll F, Dunn G, et al. (2022) Obstetric interventions and pregnancy outcomes during the COVID-19 pandemic in England: A nationwide cohort study. PLoS Med 19(1): e1003884. https://doi.org/10.1371/journal.pmed.1003884

Update 7 Janurary 2022 – Paper 77 citation updated.

Update 27 December – papers 118 and 119 added

Paper 119 – fear of Covid associated with preterm birth & low birth weight in Canada

Data from the Pregnancy During the COVID-19 Pandemic (PdP) study, collected between April 5 and December 17, 2020 (click here or paper). Citation: Giesbrecht GF, Rojas L, Patel S, Kuret V, MacKinnon AL, Tomfohr-Madsen L, Lebel C. Fear of COVID-19, mental health, and pregnancy outcomes in the Pregnancy During the COVID-19 Pandemic study: Fear of COVID-19 and pregnancy outcomes. J Affect Disord. 2021 Dec 21:S0165-0327(21)01370-7. doi: 10.1016/j.jad.2021.12.057. Epub ahead of print. PMID: 34952107.

Paper 118 – effect of lockdown in France

From four unnamed French maternity hospitals (click here or paper). Citation: Bertholdt C, Epstein J, Alleyrat C, Ambroise G, Claudel L, Banasiak C, Morel O. Comparative evaluation of the impact of the COVID-19 lockdown on perinatal experience: a prospective multicentre study. BJOG. 2021 Dec 26. doi: 10.1111/1471-0528.17082. Epub ahead of print. PMID: 34954895.

Update 13 December – papers 116 and 117 added

Paper 117 – higher risk out-of-hospital births in USA

From the CDC&P WONDER online natality database 2019 and 2020 (click here or paper). Citation: Amos Grünebaum, Eran Bornstein, Adi Katz, Frank A. Chervenak. Worsening risk profiles of out-of-hospital births during the COVID-19 pandemic Am J Obstet Gynecol. 2021

Paper 116 – Delays in obtaining abortion during pandemic in USA

From Chicago, Illinois (click here or paper). Citation: Dahl CM, Turner A, Bales C, Cheu L, Singh A, Cowett A, McCloskey L. Influence of the Coronavirus Disease 2019 (COVID-19) Pandemic on Delays in and Barriers to Abortion. Obstet Gynecol. 2021 Nov 1;138(5):805-808. doi: 10.1097/AOG.0000000000004569. PMID: 34619741; PMCID: PMC8522335.

Update 10 December – papers 114 and 115 added

Paper 115 – fewer male twins in Norway

From the Medical Birth Registry of Norway for the 59 months starting January 2016 and ending November 2020 (click here or paper). Citation: Catalano R, Bruckner T, Casey JA, Gemmill A, Margerison C, Hartig T. Twinning during the pandemic: Evidence of selection in utero. Evol Med Public Health. 2021 Oct 20;9(1):374-382. doi: 10.1093/emph/eoab033. PMID: 34858596; PMCID: PMC8634460.

Paper 114 – no effect on stillbirths, low birth weight or preterm births in France

From Lille, Nantes, Toulouse, Strasbourg, Poissy in Greater Paris, and Necker in central Paris (click here or paper). Citation: Garabedian C, Dupuis N, Vayssière C, Bussières L, Ville Y, Renaudin B, Dugave L, Winer N, Banaszkiewicz N, Rozenberg P, Defrance M, Legris ML, Quibel T, Deruelle P. Impact of COVID-19 Lockdown on Preterm Births, Low Birthweights and Stillbirths: A Retrospective Cohort Study. J Clin Med. 2021 Nov 30;10(23):5649. doi: 10.3390/jcm10235649. PMID: 34884351.

Update 29 November – papers 112 and 113 added

Paper 113 – increased preterm births in China

Singleton live infants born between 2015 and 2020 in five cities in Guangdong Province (click here or paper). Citation: Dong M, Qian R, Wang J, Fan J, Ye Y, Zhou H, Win B, Reid E, Zheng S, Lv Y, Pu Y, Chen H, Jin J, Lin Q, Luo X, Chen G, Chen Y, He Z, He G, Cheng S, Hu J, Xiao J, Ma W, Liu T, Wen X. Associations of COVID-19 lockdown with gestational length and preterm birth in China. BMC Pregnancy Childbirth. 2021 Nov 27;21(1):795. doi: 10.1186/s12884-021-04268-5. PMID: 34837991.

Paper 112 – no increased deaths in Sierra Leone

From the Sierra Leone Sample Registration System (SL-SRS) (click here or paper). Excess maternal or neonatal deaths were not detected in the months of 2020 corresponding to the peak of the COVID-19 pandemic. Citation: Carshon-Marsh R, Aimone A, Ansumana R, Swaray IB, Assalif A, Musa A, Meh C, Smart F, Hang Fu S, Newcombe L, Kamadod R, Saikia N, Gelband H, Jambai A, Jha P. Child, maternal, and adult mortality in Sierra Leone: nationally representative mortality survey 2018-20. Lancet Glob Health. 2021 Nov 25:S2214-109X(21)00459-9. doi: 10.1016/S2214-109X(21)00459-9. Epub ahead of print. PMID: 34838202.

Update 18 November – papers 108 to 111 added

Paper 111 – reduced iatrogenic, but not spontaneous, preterm births in the Netherlands

From the National Institute for Public Health and the Environment (RIVM) as extracted from Praeventis, and the Netherlands national perinatal registry, Perined (click here or paper). Citation: Klumper J, Kazemier BM, Been JV, Bloemenkamp KWM, de Boer MA, Erwich JJHM, Heidema W, Klumper FJCM, Bijvank SWAN, Oei SG, Oudijk MA, Schoenmakers S, van Teeffelen AS, de Groot CJM. Association between COVID-19 lockdown measures and the incidence of iatrogenic versus spontaneous very preterm births in the Netherlands: a retrospective study. BMC Pregnancy Childbirth. 2021 Nov 12;21(1):767. doi: 10.1186/s12884-021-04249-8. PMID: 34772364; PMCID: PMC8586024.

Paper 110 – preterm births in Scandinavia

No effect of lockdown noted (click here or paper). Citation: Oakley LL, Örtqvist AK, Kinge J, Hansen AV, Petersen TG, Söderling J, Telle KE, Magnus MC, Mortensen LH, Anne-Marie NYBOANDERSEN, Stephansson O, Håberg SE. Preterm birth after the introduction of COVID-19 mitigation measures in Norway, Sweden and Denmark: a registry-based difference-in-differences study. Am J Obstet Gynecol. 2021 Nov 11:S0002-9378(21)01231-X. doi: 10.1016/j.ajog.2021.11.034. Epub ahead of print. PMID: 34774824.

Paper 109 – Preterm births in Canada

Data from the perinatal health program and neonatal databases in the Calgary region (click here or paper). Citation: Alshaikh B, Cheung PY, Soliman N, Brundler MA, Yusuf K. Impact of Lockdown Measures during COVID-19 Pandemic on Pregnancy and Preterm Birth. Am J Perinatol. 2021 Nov 14. doi: 10.1055/s-0041-1739357. Epub ahead of print. PMID: 34775579.

Paper 108 – Preterm birth in Denmark again

From the Danish Civil Registration System, the Medical Birth Registry, and The Danish National Patient Registry (click here or paper). Citation: Hedley PL, Hedermann G, Hagen CM, Bækvad-Hansen M, Hjalgrim H, Rostgaard K, Laksafoss AD, Hoffmann S, Jensen JS, Breindahl M, Melbye M, Hviid A, Hougaard DM, Krebs L, Lausten-Thomsen U, Christiansen M. Preterm birth, stillbirth and early neonatal mortality during the Danish COVID-19 lockdown. Eur J Pediatr. 2021 Nov 16:1–10. doi: 10.1007/s00431-021-04297-4. Epub ahead of print. PMID: 34783897; PMCID: PMC8593096.

Update 1 November – paper 67 citation updated

Update 23 October – papers 106 and 107 added

Paper 107 – more gestational diabetes & hypertension in USA

Analysis of commercial and Medicare Advantage medical claims, throughout the US, collected by OptumLabs Data Warehouse (click here or paper). Citation: Sun S, Savitz DA, Wellenius GA. Changes in Adverse Pregnancy Outcomes Associated With the COVID-19 Pandemic in the United States. JAMA Netw Open. 2021;4(10):e2129560. doi:10.1001/jamanetworkopen.2021.29560

Paper 106 – more gestational diabetes & preterm births in Italy

From San Gerardo Hospital, Milan (click here or paper). Citation: Ornaghi, S., Fumagalli, S., Guinea Montalvo, C.K., Beretta, G., Invernizzi, F., Nespoli, A. and Vergani, P. (2021), Indirect impact of SARS-CoV-2 pandemic on pregnancy and childbirth outcomes: A nine-month long experience from a university center in Lombardy. International Journal of Gynecology & Obstetrics. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13990

Update 18 October – papers 104 and 105 added

Paper 105 – small reduction in preterm births in USA

From insurance claims data during the lockdown period April-June 2020 (click here or paper). Citation: Jiajia Chen PhD , Cynthia Ferre MA , Lijing Ouyang PhD , Yousra Mohamoud PhD , Wanda Barfield MD , Shanna Cox MSPH , Changes and Geographic Variation in Rates of Preterm Birth and Stillbirth during the COVID-19 Pandemic According to Health Insurance Claims in the United States, April-June 2019-2020, American Journal of Obstetrics & Gynecology MFM (2021), doi: https://doi.org/10.1016/j.ajogmf.2021.100508

Paper 104 – effect on abortion in Belgium

From one Flanders centre during the first lockdown, 16 March-14 June 2020 (click here or paper). Citation: De Kort L, Wouters E, Van de Velde S. Obstacles and opportunities: a qualitative study of the experiences of abortion centre staff with abortion care during the first COVID-19 lockdown in Flanders, Belgium. Sex Reprod Health Matters. 2021 Dec;29(1):1921901. doi: 10.1080/26410397.2021.1921901. PMID: 33982638; PMCID: PMC8128194.

Update 13 October – paper 102 added

Paper 103 – increased maternal and child deaths in 18 low and middle income countries

Lancet preprint (click here or paper). Citation: Ahmed, Tashrik and Roberton, Timothy and Team, Monitoring of Essential Health Services and Alfred, Jean Patrick and Baye, Martina L. and Diabate, Mamatou and Kiarie, Helen and Mbaka, Paul and Mohamud, Nur Ali and Mwansambo, Charles and Ndiaye, Youssoupha and Nzelu, Charles and Ofosu, Anthony and Raharison, Tsihory and Sadat, Husnia and Smart, Francis and Uddin, Helal and Wendrad, Naod and Wesseh, Chea Sanford and Yansane, Mohamad Lamine and Yuma, Sylvain and Vergeer, Petronella and Hansen, Peter Meredith and Friedman, Jed Arnold and Shapira, Gil, Indirect Effects on Maternal and Child Mortality from the COVID-19 Pandemic: Evidence from Disruptions in Healthcare Utilization in 18 Low- and Middle-Income Countries. Available at SSRN: https://ssrn.com/abstract=3916767 or http://dx.doi.org/10.2139/ssrn.3916767

Paper 102 – effect on preterm stillbirths and iatrogenic preterms in Australia

From 12 public hospitals Melbourne (click here or paper). Likely overlap with studies 85 and 95. Citation:
Lisa Hui, Melvin Barrientos Marzan, Stephanie Potenza, Daniel L. Rolnik, Natasha Pritchard, Joanne M. Said, Kirsten R Palmer, Clare L. Whitehead, Penelope M. Sheehan, Jolyon Ford, Ben W. Mol, Susan P. Walker Increase in preterm stillbirths and reduction in iatrogenic preterm births for fetal compromise: a multi-centre cohort study of COVID-19 lockdown effects in Melbourne, Australia
medRxiv 2021.10.04.21264500; doi: https://doi.org/10.1101/2021.10.04.21264500

Update 30 September 2021 – paper 101 added

Paper 101 – effect of the pandemic in India

Data from a hospital based survey since August 2018 in 15 public and private hospitals in five Indian states: Assam, Maharashtra, Uttar Pradesh, Himachal Pradesh and Meghalaya (click here or paper). Citation: Nair M, MaatHRI Writing Group, On Behalf Of The MaatHRI Collaborators. Reproductive health crisis during waves one and two of the COVID-19 pandemic in India: Incidence and deaths from severe maternal complications in more than 202,000 hospital births. EClinicalMedicine. 2021 Sep;39:101063. doi: 10.1016/j.eclinm.2021.101063. Epub 2021 Jul 29. PMID: 34585123; PMCID: PMC8461242.

Update 28 September – paper 100 added

Paper 100 – increased cannabis use in USA

From Kaiser Permanente Northern California (click here or paper). Citation: Young-Wolff KC, Ray GT, Alexeeff SE, et al. Rates of Prenatal Cannabis Use Among Pregnant Women Before and During the COVID-19 Pandemic. JAMA. Published online September 27, 2021. doi:10.1001/jama.2021.16328

Update 27 September – papers 96 to 99 added

Paper 99 – Reduced obstetric in person visits in USA

Retrospective review of prenatal and postpartum visits at Vanderbilt University Medical Center, Nashville, Tennessee (click here or paper). Citation: Osarhiemen OA, Robinson MA, Zhao Z, Ding T, Crants S, Carpenter HL, Lister RL, Assessing access to obstetric care via telehealth in the era of Covid-19, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.09.011.

Paper 98 – reduced abortions in Mexico

From the Mexico City Metropolitan Area, public abortion program, Interrupcion Legal del Embarazo (ILE) (click here or paper). Citation: Marquez-Padilla F, Saavedra B. The unintended effects of the COVID-19 pandemic and stay-at-home orders on abortions. J Popul Econ. 2021 Sep 15:1-37. doi: 10.1007/s00148-021-00874-x. Epub ahead of print. PMID: 34539084; PMCID: PMC8441247.

Paper 97 – reduced birth rate in USA

From the New York City Maternal Fetal Medicine Research Consortium, a collaboration of 13 hospitals in New York City and Long Island (click here or paper). Citation: McLaren RA Jr, Trejo FE, Blitz MJ, Bianco A, Limaye M, Brustman L, Bernstein PS, Roman AS, Stone J, Minkoff H. COVID-related “Lockdowns” and Birth Rates in New York. Am J Obstet Gynecol MFM. 2021 Aug 31:100476. doi: 10.1016/j.ajogmf.2021.100476. Epub ahead of print. PMID: 34478877.

Paper 96 – no effect on preterm birth in UK

A retrospective study from the South West region of England (click here or paper). Citation: Maslin K, McKeon-Carter R, Hosking J, Stockley L, Southby C, Shawe J, Latour JM. Preterm births in South-West England before and during the COVID-19 pandemic: an audit of retrospective data. Eur J Pediatr. 2021 Sep 17:1–5. doi: 10.1007/s00431-021-04265-y. Epub ahead of print. PMID: 34535831; PMCID: PMC8448660.

Update 10 September – paper 95 added

Paper 95 – reduced preterm births in Australia

From three hospitals in Melbourne (click here or paper). The same three hospitals, time periods and authors as paper 85. This paper analyses by date of conception. Paper 85 analysed by date of birth. Citation: Matheson A, McGannon CJ, Malhotra A, Palmer KR, Stewart AE, Wallace EM, Mol BW, Hodges RJ, Rolnik DL. Prematurity Rates During the Coronavirus Disease 2019 (COVID-19) Pandemic Lockdown in Melbourne, Australia. Obstet Gynecol. 2021 Mar 1;137(3):405-407. doi: 10.1097/AOG.0000000000004236. PMID: 33543904; PMCID: PMC7884082.

Update 2 September – papers 93 and 94 added

Paper 94 – decreased preterm births in Iran

From Akbarabadi hospital in Tehran. The pre-pandemic period (February 19 to April 19, 2019) was compared with the intra-pandemic one (February 19 to April 19, 2020) (click here or paper). Citation: Ranjbar, F., Allahqoli, L., Ahmadi, S. et al. Changes in pregnancy outcomes during the COVID-19 lockdown in Iran. BMC Pregnancy Childbirth 21, 577 (2021). https://doi.org/10.1186/s12884-021-04050-7

Paper 93 – Mixed effects of pandemic in Wales

No significant differences in gestation, birth weight, stillbirths, or Caesarean sections, but an increase in births ≥42 weeks during the first lockdown (OR: 1.28, p=0.019) and a decrease in births 32-36 weeks during the second (OR: 0.74, p=0.001). Fewer babies were born in 2020 (29,031) than the 2016-2019 average (32,582) (click here or paper). Citation: Hope Jones, Mike Seaborne, Laura Cowley, David Odd, Shantini Paranjothy, Ashley Akbari, Sinead Brophy. Population birth outcomes in 2020 and experiences of expectant mothers during the COVID-19 pandemic: a ‘Born in Wales’ mixed methods study using routine data. medRxiv 2021.08.23.21262209; doi: https://doi.org/10.1101/2021.08.23.21262209

Update 22 August – paper 92 added

Paper 92 – reduced preterm birth in China

From Shanghai First Maternity and Infant Hospital grid.459512.e (click here or paper). Citation: Bian Z, Qu X, Ying H, Liu X. Are COVID-19 mitigation measures reducing preterm birth rate in China? BMJ Glob Health. 2021 Aug;6(8):e006359. doi: 10.1136/bmjgh-2021-006359. PMID: 34385161; PMCID: PMC8361681.

Update 19 August – papers 89 to 91 added

Paper 91 – no effect of pandemic in USA

Data from Epic’s Cosmos research platform which covers one third of the hospitals in the United States (click here or paper). The period March 1 to December 31, 2020 was compared with the 3 years before the pandemic (2017–2019). See also study 794 here. Citation: Moeun Son, Kieran Gallagher, Justin Y. Lo, Eric Lindgren, Heather H. Burris, Kevin Dysart, Jay Greenspan, Jennifer F. Culhane, and Sara C. Handley. Coronavirus Disease 2019 (COVID-19) Pandemic and Pregnancy Outcomes in a U.S. Population Obstet Gynecol 2021;00:1–10) DOI: 10.1097/AOG.0000000000004547

Paper 90 – less post-partum depression screening & long acting contraception in USA

From Northwestern Memorial Hospital, Chicago, Illinois (click here or paper). Citation: Allie Sakowicz, Chloe N. Matovina, Sidney K. Imeroni, Maya Daiter, Olivia Barry, William A. Grobman, Emily S. Miller. The association between the COVID-19 pan-demic and postpartum care provision. American Journal of Obstetrics & Gynecology MFM(2021), https://doi.org/10.1016/j.ajogmf.2021.100460

Paper 89 – no major effects of lockdown in China

From the first affiliated hospital of Jinan university, Guangzhou, grid.412601.0, which has not previously reported the effects of lockdown (click here or paper). Citation: Wang J, Wang Y, He MY, Li YX, Cheng X, Yang X, Li RM, Wang G. Maternal and infant outcomes during the COVID-19 pandemic: a retrospective study in Guangzhou, China. Reprod Biol Endocrinol. 2021 Aug 17;19(1):126. doi: 10.1186/s12958-021-00807-z. PMID: 34404413.

Update 9 August – paper 88 added

Paper 88 – Fewer preterm & emergency Caesarean births in Australia

Retrospective comparison conducted in Queensland, including the Sunshine Coast University Hospital, with April 1-May 31, 2020 (lockdown), and June 1-July 31 (post-lockdown), compared to the same periods in 2018-2019 (click here or paper). Citation: Brittany Jasper, Tereza Stillerova, Christopher Anstey, Edward Weaver. Preterm birth rates during the COVID-19 lockdown in Queensland Australia. medRxiv 2021.08.06.21261711; doi: https://doi.org/10.1101/2021.08.06.21261711

Update 8 August – paper 87 added

Paper 87 – fewer Caesareans & low birth weight babies during the pandemic in Spain

From the University Hospital Marqués de Valdecilla, in Santander (click here or paper). Citation: Llorca J, Lechosa-Muñiz C, Frank de Zulueta P, López-Gómez S, Orallo V, Alonso-Molero J, Arozamena-Llano B, Jubete Y, Paz-Zulueta M, Cabero MJ, On Behalf Of The Moacc-Group. Results of Pregnancy Control before and during the COVID-19 Pandemic: A Comparison of Two Cohorts. Int J Environ Res Public Health. 2021 Aug 2;18(15):8182. doi: 10.3390/ijerph18158182. PMID: 34360483.

Update 5 August – paper 86 added

Paper 86 – No effect of first wave in Canada

No special cause variation in rates of preterm births or stillbirths during the first 12 months of the pandemic, compared with the previous 17.5 years in Ontario (click here or paper). The data likely include data reported in papers 78 and 84. Citation: Prakesh S. Shah, Xiang Y. Ye, Jie Yang, Michael A. Campitelli. Preterm birth and stillbirth rates during the COVID-19 pandemic: a population-based cohort study. CMAJ Aug 2021, 193 (30) E1164-E1172; DOI: 10.1503/cmaj.210081

Update 2 August – papers 84 and 85 added

Paper 85 – reduced preterm births in Australia

From three maternity hospitals in Melbourne (click here or paper). Citation: Rolnik DL, Matheson A, Liu Y, Chu S, McGannon C, Mulcahy B, Malhotra A, Palmer KR, Hodges RJ, Mol BW. The impact of COVID-19 pandemic restrictions on pregnancy duration and outcomes in Melbourne, Australia. Ultrasound Obstet Gynecol. 2021 Jul 26. doi: 10.1002/uog.23743. Epub ahead of print. PMID: 34309931.

Paper 84 – Effect of first wave in Canada

Singleton hospital births between March to August 2020 (and same period 2015–2019) in all of Canada, excluding Quebec (click here or paper). Citation: Liu S, Dzakpasu S, Nelson C, Wei SQ, Little J, Scott H, Joseph KS. Pregnancy outcomes during the COVID-19 pandemic in Canada, March to August 2020. J Obstet Gynaecol Can. 2021 Jul 28:S1701-2163(21)00581-8. doi: 10.1016/j.jogc.2021.06.014. Epub ahead of print. PMID: 34332116.

Update 22 July – papers 80 to 83 added

Paper 83 – no effect on stillbirths in Germany

Stillbirth rates rose slightly from 2013 to 2019, but during the first wave in early 2020, were non-significantly lower than in 2019 (click here or paper). Citation: Kniffka MS, Nitsche N, Rau R, Kühn M. Stillbirths in Germany: On the rise, but no additional increases during the first COVID-19 lockdown. Int J Gynaecol Obstet. 2021 Jul 20. doi: 10.1002/ijgo.13832. Epub ahead of print. PMID: 34287881.

Paper 82 – excess maternal deaths in Mexico.

From goverment statistics (click here or paper). This is study 271 here. Citation: Lumbreras-Marquez MI, Campos-Zamora M, Seifert SM, Kim J, Lumbreras-Marquez J, Vazquez-Alaniz F, Fields KG, Farber MK. Excess Maternal Deaths Associated With Coronavirus Disease 2019 (COVID-19) in Mexico. Obstet Gynecol. 2020 Dec;136(6):1114-1116. doi: 10.1097/AOG.0000000000004140. PMID: 32909969.

Paper 81 – reduced hospital birth in India

From Jodpur (click here or paper). This is study 343 here. The authors are from All India Institute of Medical Sciences,
Jodhpur, which is the same instutue as the different authors of paper 37. Since the time periods overlap there may some patietn overlap. Citation: Goyal M, Singh P, Singh K, Shekhar S, Agrawal N, Misra S. The effect of the COVID-19 pandemic on maternal health due to delay in seeking health care: Experience from a tertiary center. Int J Gynaecol Obstet. 2021 Feb;152(2):231-235. doi: 10.1002/ijgo.13457. Epub 2020 Dec 21. PMID: 33128794.

Paper 80 – shortened post-partum stay during first wave

From New York (click here or paper). Citation: Bornstein E, Gulersen M, Husk G, Grunebaum A, Blitz MJ, Rafael TJ, Rochelson BL, Schwartz B, Nimaroff M, Chervenak FA. Early postpartum discharge during the COVID-19 pandemic. J Perinat Med. 2020 Nov 26;48(9):1008-1012. doi: 10.1515/jpm-2020-0337. PMID: 32845868.

Update 20 July – paper 79 added

Paper 79 – reduced miscarriage during first wave

From the Ronald O. Perelman and Claudia Cohen Center for Reproductive Medicine, New York (click here or paper). Citation: Bortoletto P, Romanski PA, Stewart J, Rosenwaks Z, Pfeifer SM. Incidence of first trimester pregnancy loss in the infertile population during the first wave of the coronavirus disease 2019 pandemic in New York City. F S Rep. 2021 Apr 28;2(2):209-214. doi: 10.1016/j.xfre.2021.04.005. PMID: 34278356; PMCID: PMC8267398.

Update 18 July – paper 78 added

Paper 78 – fewer Caesarean and preterm births during lockdown in Iceland

National data (click here or paper). Citation: Einarsdóttir K, Swift EM, Zoega H. Changes in obstetric interventions and preterm birth during COVID-19: A nationwide study from Iceland. Acta Obstet Gynecol Scand. 2021 Jul 13. doi: 10.1111/aogs.14231. Epub ahead of print. PMID: 34255860.

Update 16 July – paper 46 citation updated. Paper 77 added

Paper 77 – lower ASQ scores for infants born during pandemic

According to this MedRxiv preprint, infants born during the pandemic had lower Ages & Stages Questionnaire scores than those born pre-pandemic (click here or paper). See also study 751 (click here). Citation: Lauren C. Shuffrey, Morgan R. Firestein, Margaret Kyle, Andrea Fields, Carmela Alcantara, Dima Amso, Judy Austin, Jennifer M. Bain, Jennifer Barbosa, Mary Bence, Catherine Bianco, Cristina Fernandez, Sylvie Goldman, Cynthia Gyamfi-Bannerman, Violet Hott, Yunzhe Hu, Maha Hussain, Pam Factor-Litvak, Maristella Lucchini, Arthur Mandel, Rachel Marsh, Danielle McBrian, Mirella Mourad, Rebecca Muhle, Kimberly Noble, Anna A. Penn, Cynthia Rodriguez, Ayesha Sania, Wendy G. Silver, Kally C. O Reilly, Melissa Stockwell, Nim Tottenham, Martha G. Welch, Noelia Zork, William P. Fifer, Catherine Monk, Dani Dumitriu. Birth during the COVID-19 pandemic, but not maternal SARS-CoV-2 infection during pregnancy, is associated with lower neurodevelopmental scores at 6-months medRxiv 2021.07.12.21260365; doi: https://doi.org/10.1101/2021.07.12.21260365 Update 7 January 2022 Peer reviewed version (click here or paper) Citation; Shuffrey LC, Firestein MR, Kyle MH, et al. Association of Birth During the COVID-19 Pandemic With Neurodevelopmental Status at 6 Months in Infants With and Without In Utero Exposure to Maternal SARS-CoV-2 Infection. JAMA Pediatr. Published online January 04, 2022. doi:10.1001/jamapediatrics.2021.5563

Update 29 June – paper 76 added

Paper 76 – delayed diagnosis of ectopic pregnancy in Israel

From Tel Aviv (click here or paper). Citation: Anteby M, Van Mil L, Michaan N, Laskov I, Grisaru D. Effects of the COVID-19 pandemic on timely care for extrauterine pregnancies: A retrospective analysis. Lancet Reg Health Eur. 2021 Mar;2:100026. doi: 10.1016/j.lanepe.2021.100026. Epub 2021 Jan 13. PMID: 34173625; PMCID: PMC7804379.

Update 6 June – paper 75 added

Paper 75 – increased thromboembolism during lockdown in Israel

In 2020 the rate of pregnancy-related thromboembolic events was significantly higher than in 2018 and 2019 at the Mount Scopus and Ein Kerem campuses of Hadassah-Hebrew University Medical Center in jerusalem (click here or paper). Citation: Gabrieli D, Cahen-Peretz A, Shimonovitz T, Marks-Garber K, Amsalem H, Kalish Y, Lavy Y, Walfisch A. Thromboembolic events in pregnant and puerperal women after COVID-19 lockdowns: A retrospective cohort study. Int J Gynaecol Obstet. 2021 Jun 2. doi: 10.1002/ijgo.13777. Epub ahead of print. PMID: 34077561.

Update 3 June – paper 74 added

Paper 74 – Reduced prematurity in France

Preamature births fell in single but not in multiple pregnancies (click here or paper). There was no alteration in stillbirths. Citation: Simon E, Cottenet J, Mariet A-S, Bechraoui-Quantin S, Rozenberg P, Gouyon J-B, Quantin C, Impact of the COVID-19 pandemic on preterm birth and stillbirth: a nationwide, population-based retrospective cohort study, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.05.015.

Update 29 May – paper 73 added

Paper 73 – emergency dept avoidance but no adverse effects in Canada

In Ontario, after an initial reduction, ED presentations for ectopic pregnancy quickly returned to expected levels. In contrast presentations for miscarriage showed sustained reductions but complications and mortality rates did not alter during the pandemic (click here or paper). Citation: Gomez D, Simpson AN, Sue-Chue-Lam C, de Mestral C, Dossa F, Nantais J, Wilton AS, Urbach D, Austin PC, Baxter NN. A population-based analysis of the impact of the COVID-19 pandemic on common abdominal and gynecological emergency department visits. CMAJ. 2021 May 25;193(21):E753-E760. doi: 10.1503/cmaj.202821. PMID: 34035055.

Update 27 May – paper 72 added

Paper 72 – the first wave in Ethiopia

Government health facilities in Bench Sheko, Sheka, Keffa, and West Omo zones in southern Ethiopia reported reduced antenatal, family planning and newborn immunization visits, and health facility births, and more teenage pregnancies, abortions, institutional stillbirths and neonatal deaths during March–June 2020 (click here or paper). Citation: Kassie A, Wale A, Yismaw W. Impact of Coronavirus Diseases-2019 (COVID-19) on Utilization and Outcome of Reproductive, Maternal, and Newborn Health Services at Governmental Health Facilities in South West Ethiopia, 2020: Comparative Cross-Sectional Study. Int J Womens Health. 2021 May 19;13:479-488. doi: 10.2147/IJWH.S309096. PMID: 34040456; PMCID: PMC8141395.

Update 17 May – papers 70 and 71 added

Paper 71 – more ruptured ectopic pregnancies in USA

From Newark, Delaware (click here or paper). Citation: Toma, Helen V. MD, MSPH; Bank, Tracy Caroline MD; Hoffman, Matthew K. MD, MPH Care for Women With Ectopic Pregnancies During the Coronavirus Disease 2019 (COVID-19) Pandemic, Obstetrics & Gynecology: May 06, 2021 – Volume Latest Articles – Issue – 10.1097/AOG.0000000000004392 doi: 10.1097/AOG.0000000000004392

Paper 70 – no change in preterm birth or stillbirth during first 6 months of pandemic

From Ontario, Canada (click here or paper). Citation: Simpson AN, Snelgrove JW, Sutradhar R, Everett K, Liu N, Baxter NN. Perinatal Outcomes During the COVID-19 Pandemic in Ontario, Canada. JAMA Netw Open. 2021;4(5):e2110104. doi:10.1001/jamanetworkopen.2021.10104

Update 16 May – paper 69 added

Paper 69 – More Caesareans in Brazil

From Dr. Miguel Riet Corrêa Jr., University Hospital of the Universidade Federal do Rio Grande (HU-FURG), in the state of Rio Grande do Sul (click here or paper). Citation: Manoela de Azevedo Bicho, Mayra Pacheco Fernandes, Luís Paulo Vidaletti, Juliana dos Santos Vaz. Cesarean section prevalence at a baby-friendly hospital in southern Brazil: current context in the face of COVID-19. medRxiv 2021.05.03.21256516; doi: https://doi.org/10.1101/2021.05.03.21256516

Update 15 May – paper 68 added

Paper 68 – fewer very preterm births during lockdown in Vienna

From the Viennese Danube Hospital (click here or study). Citation: Kirchengast S, Hartmann B. Pregnancy Outcome during the First COVID 19 Lockdown in Vienna, Austria. Int J Environ Res Public Health. 2021 Apr 5;18(7):3782. doi: 10.3390/ijerph18073782. PMID: 33916365; PMCID: PMC8038559.

Update 1 May – paper 67 added

Paper 67 – fewer antenatal attendances in Uganda

The authors of this MedRxiv preprint report many changes in maternity care and outcomes during the first wave at Kawempe National Referral Hospital in Kamapala (click here or paper). Citation: Jessica Burt, Joseph Ouma, Alexander Amone, Lorna Aol, Musa Sekikubo, Annettee Nakimuli, Eve Nakabembe, Robert Mboizi, Philippa Musoke, Mary Kyohere, Emily Namara, Asma Khalil, Kirsty Le Doare. Indirect Effects of COVID-19 on Maternal, Neonatal, Child, Sexual and Reproductive Health Services in Kampala, Uganda medRxiv 2021.04.23.21255940; doi: https://doi.org/10.1101/2021.04.23.21255940 Update 1 November 2021 – Peer reviewed publication (click here or paper). Citation: Burt JF, Ouma J, Lubyayi L, et alIndirect effects of COVID-19 on maternal, neonatal, child, sexual and reproductive health services in Kampala, Uganda. BMJ Global Health 2021;6:e006102.

Update 21 April – Paper 66 added

Paper 66 – increase in molar pregnancy in Israel

A doubling in the incidence of molar pregnancies at Galilee Medical Center, Nahariya, in January–October, 2020 (click here or paper). Citation: Aiob A, Naskovica K, Sharon A, Bornstein J. A possible association between hydatidiform mole and the COVID-19 pandemic: A retrospective cohort study. Gynecol Oncol. 2021 Mar 5:S0090-8258(21)00192-X. doi: 10.1016/j.ygyno.2021.02.035. Epub ahead of print. PMID: 33712273; PMCID: PMC7934616.

Update 11 April – papers 64 and 65 added

Paper 65 – fewer births and terminations in Italy

From the Institute for Maternal and Child Health, Trieste (click here or paper). Citation: Trombetta A, Travan L, Elefante P, Canton M, Rispoli F, Maso G, Barbi E, Risso FM. The first Italian COVID-19 lockdown reduced births and voluntary terminations by just under a fifth. Acta Paediatr. 2021 Mar 29. doi: 10.1111/apa.15862. Epub ahead of print. PMID: 33780031.

Paper 64 – reduced preterm birth rate in Saudi Arabia

From King Saud Medical City, Riyadh (click here or paper). Citation: Huseynova R, Bin Mahmoud L, Abdelrahim A, Al Hemaid M, Almuhaini MS, Jaganathan PP, Career H, Huseynov O. Prevalence of Preterm Birth Rate During COVID-19 Lockdown in a Tertiary Care Hospital, Riyadh. Cureus. 2021 Mar 1;13(3):e13634. doi: 10.7759/cureus.13634. PMID: 33816033; PMCID: PMC8011548.

Update 30 March – paper 63 added

Paper 63 – national changes in US

This MedRxiv preprint reports a fall in live births, preterm births and low birth weight babies in the United States during the pandemic (click here or paper). Citation: Alison Gemmill, Joan A. Casey, Ralph Catalano, Deborah Karasek, Tim Bruckner. Changes in live births, preterm birth, low birth weight, and cesarean deliveries in the United States during the SARS-CoV-2 pandemic. medRxiv 2021.03.20.21253990; doi: https://doi.org/10.1101/2021.03.20.21253990

Update 21 March – papers 61 and 62 added

Paper 62 – fewer OBGYN emergency hospital visits during first wave

Data from Kaiser Permanente Northern California, Oakland (click here or ). Citation: Abel, Mary Kathryn AB; Alavi, Mubarika X. MS; Tierney, Cassidy MD; Weintraub, Miranda Ritterman PhD, MPH; Avins, Andrew MD, MPH; Zaritsky, Eve MD Coronavirus Disease 2019 (COVID-19) and the Incidence of Obstetric and Gynecologic Emergency Department Visits in an Integrated Health Care System, Obstetrics & Gynecology: March 10, 2021 – Volume Latest Articles – Issue – 10.1097/AOG.0000000000004331 doi: 10.1097/AOG.0000000000004331 

Paper 61 – more abortion referrals and procedures during first wave.

From author affiliations the unnamed Northern California tertiary referral center may have been Dept. OBGYN, University of California, Davis, in Sacramento (click here or PgwZqt-PIIS0002937821001587). Citation: Creinin MD, Tougas H, Wilson M, Matulich MC, COVID-19 impact on abortion care at a Northern California tertiary family planning program American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.03.007. 

Update 20 March – paper 60 added

Paper 60 – no change in ethnic disparities in preterm birth in New York

Women who delivered from March 28 to July 31, 2020, in New York City, were compared with women who delivered from March 28 to July 31, 2019 (click here or janevic_2021_oi_210084_1615398911.43761). Citation: Janevic T, Glazer KB, Vieira L, Weber E, Stone J, Stern T, Bianco A, Wagner B, Dolan SM, Howell EA. Racial/Ethnic Disparities in Very Preterm Birth and Preterm Birth Before and During the COVID-19 Pandemic. JAMA Netw Open. 2021 Mar 1;4(3):e211816. doi: 10.1001/jamanetworkopen.2021.1816. PMID: 33729505.

Update 3rd March – papers 58 and 59 added. Additional data & citation paper 10. Paper 15 (abstract) and paper 22 (full paper) noted to report the same data.

Paper 59 – no change in preterm births in Massachussetts

Preterm birth rates, defined in various ways, did not alter significantyl in four Boston hospitals during the pandemic, compared with the previous year (click here or Preterm_Birth_During_the_Coronavirus_Disease_2019.2). Citation: Wood, Rachel MD; Sinnott, Colleen MD; Goldfarb, Ilona MD; Clapp, Mark MD, MPH; McElrath, Thomas MD, PhD; Little, Sarah MD, MPH Preterm Birth During the Coronavirus Disease 2019 (COVID-19) Pandemic in a Large Hospital System in the United States, Obstetrics & Gynecology: March 2021 – Volume 137 – Issue 3 – p 403-404. doi: 10.1097/AOG.0000000000004237 

Paper 58 – Increased stillbirths in India

Stillbirths were significantly increased during the pandemic in a large New Delhi hospital compared with the previous year (click here or ijgo.13564). Citation: Kumar, M., Puri, M., Yadav, R., Biswas, R., Singh, M., Chaudhary, V., Jaiswal, N. and Meena, D. (2021), Stillbirths and the COVID‐19 pandemic: Looking beyond SARS‐CoV‐2 infection. Int J Gynecol Obstet. https://doi.org/10.1002/ijgo.13564

Update 27 February – Papers 56 and 57 added

Paper 57 – Slightly fewer preterm births in Pittsburg

At University of Pittsburgh Medical Centres, Magee-Womens Hospital, births <37 weeks fell from 11.1% (1 Jan 2018 to 31 Jan 2020 pre-pandemic) to 10.1% (1 April 2020 to 27 October 2020 pandemic) (click here or 1-s2.0-S2589933321000252-main). Citation: Lara Lemon, Robert P. Edwards, Hyagriv N. Simhan. What is driving the decreased incidence of preterm birth during the COVID-19 pandemic? American Journal of Obstetrics & Gynecology MFM (2021), doi: https://doi.org/10.1016/j.ajogmf.2021.100330&nbsp;

Paper 56 – Effect of lockdown in Beijing, China

No major effects seen (click here or e047900.full). Citation: Du M, Yang J, Han N, et alAssociation between the COVID-19 pandemic and the risk for adverse pregnancy outcomes: a cohort studyBMJ Open 2021;11:e047900. doi: 10.1136/bmjopen-2020-047900

Update 25 February – paper 55 added

Paper 55 – HSIB first wave maternal death report

The UK Healthcare Safety Investigation Branch (HSIB) reviewed 20 maternal deaths (19 included in review) that occurred between 1 March and and 31 May 2020 (the first peak of the COVID-19 pandemic in England) (click here or HSIB_Maternal_Death_Report_V13). Citation: National Learning Report. Maternal death: learning from maternal death investigations during the first wave of the COVID-19 pandemic. Independent report by the Healthcare Safety Investigation Branch I2020/017. February 2021. 

Update 21 February – paper 54 added

Paper 54 – Delayed diagnosis of ectopic pregnancy in Israel

From Shaare Zedek Medical Center, Jerusalem (click here or ijgo.13647). Citation: Barg M, Rotem R, Mor P, Rottenstreich M, Fayez K, Grisaru-Granovsky S, Armon S. Delayed presentation of ectopic pregnancy during the COVID-19 pandemic: A retrospective study of a collateral effect. Int J Gynaecol Obstet. 2021 Feb 18. doi: 10.1002/ijgo.13647. Epub ahead of print. PMID: 33599285.

Update 13 February – paper 53 added

Paper 53 – no effect of pandemic on assisted reproduction outcomes in Italy

From Lombardy (click here or LeviSetti preprint 2021). Citation: Paolo Emanuele Levi-Setti, Federico Cirillo, Valentina Immediata et al. First Trimester Pregnancy Outcomes in a Large&nbsp;ART Center From the Lombardy County (Italy) During the Peak COVID-19 Pandemic., 08 February 2021, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-152522/v1]

Update 1 February – paper 52 added

Paper 52 – first wave hospital births in Israel

Poster presented at the Society of Materno-Fetal Medicine 2021 conference (SMFM 2021) . Fewer hospital births, and higher induction and Caesarean rates during the first wave at Shaare Zedek Medical Center in Jerusalem. Citation to follow.

Update 13 January – paper 51 added

Paper 51 – no association with preterm birth or stillbirth in Sweden

In this national registry study there was no increase in preterm births, or in stillbirths, over the period 1 April through 31 May 2020, compared with the same period over the previous five years (click here or m20-6367). Citation: Pasternak B, Neovius M, Söderling J, Ahlberg M, Norman M, Ludvigsson JF, Stephansson O. Preterm Birth and Stillbirth During the COVID-19 Pandemic in Sweden: A Nationwide Cohort Study. Ann Intern Med. 2021 Jan 12. doi: 10.7326/M20-6367. Epub ahead of print. PMID: 33428442.

Update 9 January – paper 50 added

Paper 50 – fewer & later pregnancy terminations in Texas

The effect of an executive order between March 22 and April 21, to postpone surgery that was not medically necessary, and which was interpreted by some as including abortion, is described (click here or jama_white_2021_ld_200123_1609269106.91809). Citation: White K, Kumar B, Goyal V, Wallace R, Roberts SCM, Grossman D. Changes in Abortion in Texas Following an Executive Order Ban During the Coronavirus Pandemic. JAMA. Published online January 04, 2021. doi:10.1001/jama.2020.24096

Update 2 January – paper 49 added

Paper 49 – more ruptured ectopics during first wave

The ratio of ruptured to unruptured ectopic pregnancies rose between March 15th and May 17th 2020 at Lenox Hill Hospital, New York (click here or ijcp.13925). Citation: Werner, S, Katz, A. Change in ectopic pregnancy presentations during the covid‐19 pandemic. Int J Clin Pract. 2020; 00:e13925. https://doi.org/10.1111/ijcp.13925

Update 23 December – Paper 48 added

Paper 48 – No major adverse effect of lockdown in Botswana

No increase in adverse perinatal outcomes during or after lockdown in Botswana. Rather, a modest reduction, driven primarily by reduced preterm birth and growth restriction (click here or caniglia AJOG 2020 (002)). Time period of lockdown validated against Facebook geolocation data. Citation: CANIGLIA EC, MAGOSI LE, ZASH R, DISEKO M, MAYONDI G, MABUTA J, POWIS K, DRYDEN-PETERSON S, MOSEPELE M, LUCKETT R, MAKHEMA J, MMALANE M, LOCKMAN S, SHAPIRO R, Modest reduction in adverse birth outcomes following the COVID-19 lockdown, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2020.12.1198.

Update 19 December – papers 46 and 47 added

Paper 47 – Antenatal care during lockdown in Ethiopia

Pregnant women attending ANC services at public hospitals in Northeast Ethiopia between February 2 & August 30, 2020 (click here or ijwh-287534-antenatal-care-service-utilization-of-pregnant-women-attendi). No control group. Citation: Tadesse E. Antenatal Care Service Utilization of Pregnant Women Attending Antenatal Care in Public Hospitals During the COVID-19 Pandemic Period. Int J Womens Health. 2020;12:1181-1188. Published 2020 Dec 8. doi:10.2147/IJWH.S287534

Paper 46 – Fewer planned moderately preterm births in an Australian hospital

During the 2020 lockdown, rates of planned (iatrogenic) moderately preterm birth fell in the Mater Mothers’ Hospital, South Brisbane, Queensland (click here or 2020.11.24.20237529.full). Outcomes not reported. Citation: Linda A. Gallo, Tania F. Gallo, Danielle J. Borg, Karen M. Moritz, Vicki L. Clifton, Sailesh Kumar. Preterm birth rates in a large tertiary Australian maternity centre during COVID-19 mitigation measures medRxiv 2020.11.24.20237529; doi: https://doi.org/10.1101/2020.11.24.20237529 Update 16 July – peer reviewed version published (click here or paper). Citation: Gallo LA, Gallo TF, Borg DJ, Moritz KM, Clifton VL, Kumar S. A decline in planned, but not spontaneous, preterm birth rates in a large Australian tertiary maternity centre during COVID-19 mitigation measures. Aust N Z J Obstet Gynaecol. 2021 Jul 12. doi: 10.1111/ajo.13406. Epub ahead of print. PMID: 34254286.

Update 15 December – paper 45 added

Paper 45 – fewer visits during lockdown in Nanjing, China

Hospital visits for pregnancy care fell during lockdown in Zhongda Hospital, Southeast University, Nanjing, Jiangsu Province, China grid.452290.8 (click here or 10.1177_0300060520939337). There were no reported harms. Citation: Gu XX, Chen K, Yu H, Liang GY, Chen H, Shen Y. How to prevent in-hospital COVID-19 infection and reassure women about the safety of pregnancy: Experience from an obstetric center in China. J Int Med Res. 2020;48(7):300060520939337. doi:10.1177/0300060520939337

Update 14 December – paper 44 added

Paper 44 – increased stillbirths during 1st wave in Israel

Stillbirth were increased in the period  February 21 to April 30 2020, compared with the corresponding periods for 2017 to 2019 in Shamir Medical Center, Zerifin, Israel (click here or s-0040-1721515). Citation: Matan Mor, Nadav Kugler, Eric Jauniaux, Moshe Betser, Yifat Wiener, Howard Cuckle, Ron Maymon. Impact of the COVID-19 Pandemic on Excess Perinatal Mortality and Morbidity in Israel. Am J Perinatol DOI: 10.1055/s-0040-1721515

Update 10th December – paper 43 added

Paper 43 – rise in the rate of ruptured ectopic pregnancies

In Sant’Orsola-Malpighi University Hospital in Bologna, Italy, the rate of ruptured ectopic pregnancies normally 52/201 (26%) rose to 6/9 (66%) during the first lockdown period (click here or uog.22126). Citation: Casadio, P., Youssef, A., Arena, A., Gamal, N., Pilu, G. and Seracchioli, R. (2020), Increased rate of ruptured ectopic pregnancy in COVID‐19 pandemic: analysis from the North of Italy. Ultrasound Obstet Gynecol, 56: 289-289. https://doi.org/10.1002/uog.22126

Update 8th December – papers 41 and 42 added

Paper 42 – no significant alteration in stillbirths during first wave in England

There was no significant alteration in stillbirths overall, or in any region of the UK during the first wave (click here or jama_stowe_2020_ld_200113_1607178377.6775) Citation: Stowe J, Smith H, Thurland K, Ramsay ME, Andrews N, Ladhani SN. Stillbirths During the COVID-19 Pandemic in England, April-June 2020. JAMA. Published online December 07, 2020. doi:10.1001/jama.2020.21369

Paper 41- no significant alteration in preterm births or in stillbirths during first wave in Philadelphia

There were no significant alterations in the patterns, or overall rates, of preterm births or stillbirths during the first wave, in two Philadelphia hospitals (click here or jama_handley_2020_ld_200111_1607178374.44311 (1)). Citation: Handley SC, Mullin AM, Elovitz MA, et al. Changes in Preterm Birth Phenotypes and Stillbirth at 2 Philadelphia Hospitals During the SARS-CoV-2 Pandemic, March-June 2020. JAMA. Published online December 07, 2020. doi:10.1001/jama.2020.20991

Update 7th December – paper 40 added

Paper 40 – 16 maternal deaths in Indonesia

From March to May 2020, 16 pregnant or postnatal women died in West Sumatra (click here or 10.1080@0167482X.2020.1779216). It is not reported whether these were caused by Covid-19 or other diseases. Citation: Mijke Lambregtse-van den Berg, Julie Quinlivan. (2020) Identifying pregnant women at risk of developing COVID-19 related mental health problems – a call for enhanced psychoeducation and social support. Journal of Psychosomatic Obstetrics & Gynecology 41:4, pages 249-250.

Update 5th December – papers 38 and 39 added

Paper 39 – no major obstetric effects of lockdown in Wuhan, China

The Maternal and Child Hospital of Hubei Province (which I believe is part of Huazhong University of Science and Technology Hospital grid.488485.d) observed no major effects of lockdown compared with the previous year (click here or journal.pone.0237420). The Caesarean rate, for example, rose from 47% to 48%. Citation: Li M, Yin H, Jin Z, Zhang H, Leng B, Luo Y, Zhao Y. Impact of Wuhan lockdown on the indications of cesarean delivery and newborn weights during the epidemic period of COVID-19. PLoS One. 2020 Aug 13;15(8):e0237420. doi: 10.1371/journal.pone.0237420. PMID: 32790709; PMCID: PMC7425855.

Paper 38 – reduced prenatal diagnosis procedures Trabzon, Turkey

Between 11 March and 30 June 2020 prenatal dignosis procedures reduced by about one third at Karadeniz Perinatology Clinic, compared with the same period in the previous year (click here or Effect of COVID 19 pandemic process on prenatal diagnostic procedures (1)). Citation: Mirac Ozalp, Omer Demir, Hümeyra Akbas, Ecem Kaya, Cemre Celik & Mehmet Armagan Osmanagaoglu (2020) Effect of COVID-19 pandemic process on prenatal diagnostic procedures, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1815190

Update 3rd December – paper 37 added

Paper 37 – Reduced hospitalisation & increased maternal & perinatal mortality in Jodhpur, India

Reduced hospitlisation and emergency referrals after lockdown, coincided with increased in-hospital maternal mortality, and late intrauterine fetal death and stillbirth in a group of four hospitals associated with Dr S N Medical College, Jodhpur, India (click here or PIIS2214109X20303193). Citation: Kumari V, Mehta K, Choudhary R. COVID-19 outbreak and decreased hospitalisation of pregnant women in labour. Lancet Glob Health. 2020 Sep;8(9):e1116-e1117. doi: 10.1016/S2214-109X(20)30319-3. Epub 2020 Jul 14. PMID: 32679037.

Update 2nd December – papers 35 and 36 added

Paper 36 – freebirth due to fear of Covid in Iran

A woman from Dezful, Khuzestan province in Iran had a normal birth alone at home because she was fearful of contracting Covid-19 in hospital (click here or IJPS-15-366). Both mother and baby were fine. Citation: Nosratabadi M, Sarabi N, Masoudiyekta L. A Case Report of Vaginal Delivery at Home due to Fear of Covid-19. Iran J Psychiatry. 2020;15(4):366-369. doi:10.18502/ijps.v15i4.4306

Paper 35 – delayed presentation in labour in Sao Paolo, Brazil

In São Paulo Hospital betwee March 11 and June 11, more women presented in advanced labour (click here or ijgo.13357). Citation: Sun, S.Y., Guazzelli, C.A.F., de Morais, L.R., Dittmer, F.P., Augusto, M.N., Soares, A.C., Coutinho da Silva, P.M., Abuchaim, E.d.S.V. and Mattar, R. (2020), Effect of delayed obstetric labor care during the COVID‐19 pandemic on perinatal outcomes. Int J Gynecol Obstet, 151: 287-289. https://doi.org/10.1002/ijgo.13357

Update 1st December – papers 32 to 34 added

Paper 34 – reduced risk of post partum depression during lockdown

Rates of raised EPDS scores were reduced during lockdown among women cared for at Soroka University Medical Center, Negev, Israel (click here or Pariente2020_Article_RiskForProbablePost-partumDepr). Citation: Pariente, G., Wissotzky Broder, O., Sheiner, E. et al. Risk for probable post-partum depression among women during the COVID-19 pandemic. Arch Womens Ment Health (2020). https://doi.org/10.1007/s00737-020-01075-3

Paper 33 – breast feeding during lockdown in Belgium

Reported behaviour of a self-selected sample (click here or ijerph-17-06766). Most women reported continuing breast feeding for longer during lockdown. Citation: Ceulemans, M.; Verbakel, J.Y.; Van Calsteren, K.; Eerdekens, A.; Allegaert, K.; Foulon, V. SARS-CoV-2 Infections and Impact of the COVID-19 Pandemic in Pregnancy and Breastfeeding: Results from an Observational Study in Primary Care in Belgium. Int. J. Environ. Res. Public Health 2020, 17, 6766.

Paper 32 – sexual behaviour during lockdown in China

Reported behaviour of a self-selected sample (click here or pdf (1)). Citation. Li G, Tang D, Song B, Wang C, Qunshan S, Xu C, Geng H, Wu H, He X, Cao Y. Impact of the COVID-19 Pandemic on Partner Relationships and Sexual and Reproductive Health: Cross-Sectional, Online Survey Study. J Med Internet Res. 2020 Aug 6;22(8):e20961. doi: 10.2196/20961. PMID: 32716895; PMCID: PMC7419154.

Update 27 November – paper 31 added

Paper 31 – effect of lockdown in Karnataka, India

The self-reported effects of lockdown of 290/315 pregnant women attending Shri B.M. Patil Medical College, Hospital and Research Center, Vijayapura, Karnataka, India, between 21/05/2020 & 08/06/2020 (click here or pmr-12-03-3). Citation: Dr. Rajasri G. Yaliwal, Dr. Aruna M.Biradar, Dr. Shreedevi S. Kori, Dr. Subhashchandra, R. Mudanur, Dr. Shivakumar U. Pujeri, Dr. Shailaja R. Bidri, Dr. Neelamma G. Patil. CHALLENGES OF PREGNANCY DURING THE COVID19 PANDEMIC AND LOCKDOWN –A CROSS-SECTIONAL STUDY. Pravara Med Rev; September 2020, 12(03) , 23-30 DOI: 10.36848/PMR/2020/13100.51291

Update 26 November – papers 29 and 30 added

Paper 30 – more women not receiving antenatal care in Jordan

The self-reported rate of women not receiving antenatal care in this online survey of self-selected members of women’s and motherhood groups in Jordan, rose from a recalled 38/944 (4%) before lockdown to 562 (60%) during lockdown (click here or ijwh-280342-pregnancy-during-covid-19-outbreak-the-impact-of-lockdown-i). Citation: Muhaidat N, Fram K, Thekrallah F, Qatawneh A, Al-Btoush A. Pregnancy During COVID-19 Outbreak: The Impact of Lockdown in a Middle-Income Country on Antenatal Healthcare and Wellbeing. Int J Womens Health. 2020;12:1065-1073 https://doi.org/10.2147/IJWH.S280342

Paper 29 – couples delaying conception in Shanghai, China

Of 447 couples who had been recorded before the pandemic as planning to conceive a pregnancy, 151 (34%) stated that they had altered their plans, presumably in the direction of cancelling or delaying trying for a baby (click here or ijgo.13366). Citation: Zhu, C., Wu, J., Liang, Y., Yan, L., He, C., Chen, L. and Zhang, J. (2020), Fertility intentions among couples in Shanghai under COVID‐19: A cross‐sectional study. Int. J. Gynecol. Obstet., 151: 399-406. https://doi.org/10.1002/ijgo.13366

Update 24th November – paper 28 added

Paper 28 – fewer & later attendances in pregnancy during first wave in Israel

Fewer pregnant women attended the emergency department during the first wave compared with the same period in the previous year, and those that did attended at later gestations or at more advanaced stages of labour. Hower, no differences were seen in outcomes (click here or Changes in the obstetrical emergency department profile during the COVID 19 pandemic). From author affiliations this was probably Carmel Medical Center, Haifa, Israel. Citation: Nir Kugelman, Ofer Lavie, Wisam Assaf, Nadav Cohen, Lena Sagi-Dain, Mordehai Bardicef, Reuven Kedar, Amit Damti & Yakir Segev (2020) Changes in the obstetrical emergency department profile during the COVID-19 pandemic, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1847072

Update 23rd November – paper 27 added

Paper 27 – cancelled clinic appointments in Iran

57/103 pregnant or post-partum women reported cancelling clinic appointments for themselves or their child during lockdown (click here or ijerph-17-08272). Participants were patients in the Department of Gynecology and Midwifery of the Arak University of Medical Sciences, Arak, Iran. Citation: Shayganfard, M.; Mahdavi, F.; Haghighi, M.; Sadeghi Bahmani, D.; Brand, S. Health Anxiety Predicts Postponing or Cancelling Routine Medical Health Care Appointments among Women in Perinatal Stage during the Covid-19 Lockdown. Int. J. Environ. Res. Public Health 2020, 17, 8272.

Update 20 November – paper 26 added

Paper 26 – no alteration in miscarriage rate after embryo transfer in New York

The authors of this conference abstract report that early pregnancy loss rates did not alter during the first wave of the SARS-CoV-2 pandemic (click here or PIIS0015028220323165). Citation: Flisser, Eric et al. PREGNANCY LOSS RATES AFTER SINGLE, EUPLOID FROZEN-THAWED EMBRYO TRANSFER IN THE COVID-19 ERA. Fertility and Sterility, Volume 114, Issue 3, e561 – e562

Update 14 November – paper 25 added

Paper 25 – more stillbirths & fewer late preterm births in Rome, Italy

Using the Lazio region hospital discharge database, the authors report fewer 32-36w births, & more stillbirths in March to May 2020, compared with the same period 2019 (click here or archdischild-2020-320682.full). Citation: De Curtis M, Villani L, Polo A. Arch Dis Child Fetal Neonatal Ed Epub ahead of print: doi:10.1136/archdischild-2020-320682 Accepted 21 October 2020 Arch Dis Child Fetal Neonatal Ed 2020;0:F1. doi:10.1136/fetalneonatal-2020-320682

Update 12 November – papers 22 to 24 added

Paper 24 – hospital births and postnatal depression scores in Hong Kong

Queen Mary Hospital, Pokfulam, Hong Kong observed a fall in hospital births and raised rates of Edinburgh postnatal depression scores over 10 during lockdown (click here or hkmj208774). Citation: PW Hui, Grace Ma, Mimi TY Seto, KW Cheung. Effect of COVID-19 on delivery plans and postnatal depression scores of pregnant women. Hong Kong Med J 2020;26:Epub 5 Nov 2020 https://doi.org/10.12809/hkmj208774

Paper 23 – stress during lockdown in Cork, Ireland

This survey reported no major differences in a range of self-reported psychological or behavioural outcomes during lockdown (click here or 1-s2.0-S187151922030367X-main). Citation: Karen Matvienko-Sikar, Johanna Pope, Avril Cremin, Hayley Carr, Sara Leitao, Ellinor K. Olander, Sarah Meaney. Differences in levels of stress, social support, health behaviours, and stress-reduction strategies for women pregnant before and during the COVID-19 pandemic, and based on phases of pandemic restrictions, in Ireland. Women and Birth. 2020,ISSN 1871-5192, https://doi.org/10.1016/j.wombi.2020.10.010. (http://www.sciencedirect.com/science/article/pii/S187151922030367X)

Paper 22 – lockdown did not affect miscarriage rates in Montreal, Canada

There was no difference in miscarriage/non-viable pregnancy rates in this Montreal fertility unit, between the period of the first wave, and an equivalent period in 2019 (click here or Rotshenker-Olshinka2020_Article_COVID-19PandemicEffectOnEarlyP). Citation: Rotshenker-Olshinka, K., Volodarsky-Perel, A., Steiner, N. et al. COVID-19 pandemic effect on early pregnancy: are miscarriage rates altered, in asymptomatic women?. Arch Gynecol Obstet (2020). https://doi.org/10.1007/s00404-020-05848-0 3 March update. This is the full report of paper 15 (abstract)

Update 10th November – paper 21 added

Paper 21 – shorter postnatal stay during pandemic in Los Angles

Women and babies who delivered in March and April 2020 at Cedars-Sinai Medical Center, Los Angeles, California, USA, had significantly reduced postpartum stays than those in prepandemic periods (click here or Greene AJOG MFM-main). No adverse effects were reported. Citation: Greene NH, Kilpatrick SJ, Wong MS, et al. Impact of labor and delivery unit policy modifications on maternal and neonatal outcomes during the coronavirus disease 2019 pandemic. Am J Obstet Gynecol MFM 2020;2:100234. https://doi.org/10.1016/j.ajogmf.2020.100234

Update 9th November – papers 19 and 20 added

Paper 20 – halving of emergency admissions during the pandemic in Bologna, Italy

In March 2020, the middle of the COVID-19 pandemic, emegency room attendances halved compared with March 2019 in S.Orsola-Malpighi University Hospital of Bologna (click here or Salsi AJOG MFM). Citation: Ginevra Salsi, Anna Seidenari, Josefina Diglio, Federica Bellussi, Gianluigi Pilu, Federica Bellussi. Obstetrics and gynecology emergency services during the coronavirus disease 2019 pandemic. American Journal of Obstetrics & Gynecology MFM, Volume 2, Issue 4, Supplement, 2020, 100214, ISSN 2589-9333, https://doi.org/10.1016/j.ajogmf.2020.100214. (http://www.sciencedirect.com/science/article/pii/S2589933320301828)

Paper 19 – halving of admissions & births during the pandemic in Jodhpur, India

Over the period of the pandemic, hospital admissions in pregnancy, and hospital births halved in the All India Institute of Medical Sciences, Jodhpur, a tertiary referral hospital (click here or ijgo.13457). 32 pregnant women with Covid-19 were included, so this paper is also included as study 343 here. Citation: Goyal, M., Singh, P., Singh, K., Shekhar, S., Agrawal, N. and Misra, S. (2020), The effect of the COVID‐19 pandemic on maternal health due to delay in seeking health care: Experience from a tertiary center. International Journal of Gynecology & Obstetrics. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13457

Update 31st October – paper 18 added

Paper 18 – no effect on preterm births in California

No effect on preterm births over the pandemic first wave in California, apart from a small “increase” in births between 28 and 32 weeks (click here or Main AJOG 21 oct 2020 (1)). Citation: Main EK, Chang S-C, Carpenter AM, Wise PH, Stevenson DK, Shaw GM, Gould JB, Preterm birth rates for racial and ethnic groups during the COVID-19 pandemic in California, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.10.033.

Update 24 October – papers 16 and 17 added

Paper 17 – reduced general anaesthesia for Caesarean during lockdown, UK

Six hospitals observed a fall in Caesarean general anaesthesia rates from 7.7 to 3.7% during the pandemic (click here or ). Citation; Bhatia K, Columb M, Bewlay A, Eccles J, Hulgur M, Jayan N, Lie J, Verma D, Parikh R. The effect of COVID-19 on general anaesthesia rates for caesarean section. A cross sectional analysis of six hospitals in the north-west of England. Anaesthesia. 2020 Oct 18. doi: 10.1111/anae.15313. Epub ahead of print. PMID: 33073371.

Paper 16 – reduced preterm birth in a Philadelphia hospital

In Thomas Jefferson University Hospital preterm birth fell from 13% in March 1-July 31 2019, to 10% in March 1-July 31 2020 (click here or berghella AJOGMFM). Citation: Berghella V, Burd J, Anderson K, Boelig R, Roman A, Decreased incidence of preterm birth during COVID-19 pandemic, American Journal of Obstetrics & Gynecology MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100258.

Update 20 October – papers 13 to 15 added

Paper 15  – miscarriage before and during lockdown in Montreal, Canada

No change (click here or main (4)) Citation: Olshinka KR, Volodarsky-Perel A, Steiner N, Rubenfeld ES, Dahan MH. COVID-19 PANDEMIC EFFECT ON EARLY PREGNANCY – ARE MISCARRIAGE RATES ALTERED, IN ASYMPTOMATIC WOMEN?. Fertil Steril. 2020;114(3):e525-e526. doi:10.1016/j.fertnstert.2020.09.036 March 3rd update. The full version of this abstract is reported in paper 22.

Paper 14 – diabetes control during lockdown in Lille, France

It deteriorated (click here or main (3)). Citation: Ghesquière L, Garabedian C, Drumez E, et al. Effects of COVID-19 pandemic lockdown on gestational diabetes mellitus: A retrospective study [published online ahead of print, 2020 Oct 15]. Diabetes Metab. 2020;doi:10.1016/j.diabet.2020.09.008

Paper 13 – the Covid-19 New Mum survey

Self-selected and self-reported UK maternal birth experiences before and after lockdown (click here or main (2)). Citation: A. Vazquez-Vazquez, Appetite, https://doi.org/10.1016/j.appet.2020.104985

Update 18 October – papers 10 to 12 added

Paper 12 – reduced preterm birth in The Netherlands

National study based on dried blood spot screening programme (click here or PIIS2468266720302231). Citation: Been, Jasper V et al. Impact of COVID-19 mitigation measures on the incidence of preterm birth: a national quasi-experimental study. The Lancet Public Health, Volume 0, Issue 0. https://doi.org/10.1016/S2468-2667(20)30223-1

Paper 11 – reduced preterm births in Dublin, Ireland

There was a small reduction in preterm birth, but no other effects, between 1st January & 31st July 2020 compared to the same period in 2019 in the Coombe Women & Infants University Hospital (click here or PIIS0301211520306539). Citation: McDonnell S, McNamee E, Lindow SW, O’Connell MP, The impact of the Covid-19 pandemic on maternity services: a review of maternal and neonatal outcomes before, during and after the pandemic, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.10.023

Paper 10 – reduced preterm births in Israel (update 3 March)

This preprint consists only of results tables (click here or PIIS0002937820311911 (1)). The corresponding author is from Chaim Sheba Medical Center, Israel. Citation: Meyer R, Friedrich L, Maixner N, Bart Y, Tsur A, Yinon Y, Levin G, A marked decrease in Preterm Deliveries during the COVID-19 Pandemic, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.10.017. Update 3 March. This paper (click here or 244117) with overlapping authorship, also reports the effect of lockdown in the same hospital. Citation:  Meyer R, Levin G, Hendin N, Katorza E. Impact of the COVID-19 Outbreak on Routine Obstetrical Management. Isr Med Assoc J. 2020 Aug;22(8):483-488. PMID: 33236580.

Update 12 October – papers 8 and 9 added

Paper 9 – effect of lockdown in one hospital in Israel

Various pregnancy complications  over March–April 2020 (the peak COVID-19 outbreak) in one large hospital, were compared with March–April 2019 in the same hospital (click here or 231152 (002)). From author affiliations the hospital was probably Rambam Health Care Campus in Haifa. Citation: Justman N, Shahak G, Gutzeit O, Ben Zvi D, Ginsberg Y, Solt I, Vitner D, Beloosesky R, Weiner Z, Zipori Y. Lockdown with a Price: The impact of the COVID-19 Pandemic on Prenatal Care and Perinatal Outcomes in a Tertiary Care Center. Isr Med Assoc J. 2020 Sep;9(22):467-471. PMID: 32954690.

Paper 8 – effect of lockdown in one hospital in Japan

The rates of women hospitalised for some pregnancy complications in Keio University Hospital between April 1st and June 30th, 2020, were compared with the same period 2017-19 (click here or jog.14518). No substantive outcomes reported. Citation: Kasuga, Y., Tanaka, M. and Ochiai, D. (2020), Preterm delivery and hypertensive disorder of pregnancy were reduced during the COVID‐19 pandemic: A single hospital‐based study. J. Obstet. Gynaecol. Res.. doi:10.1111/jog.14518

Update 9 October – papers 6 and 7 added

Paper 7 – reduced admission to emergency OBGYN during first wave in Milan, Italy

Between February 24th & May 31st 2020 emergency OBGYN admissions decreased by 35% at Clinica Mangiagalli, the largest maternity clinic in Milan, compared with the corresponding period in 2019   (click here or 1-s2.0-S0301211520305777-main). Five fetal deaths were seen in the emergency clinic in the pandemic period compared with one in the earlier period. Total perinatal deaths were not reported for either period. Citation: Chiara Dell’Utri, Elisabetta Manzoni, Sonia Cipriani, Claudio Spizzico, Andrea Dell’Acqua, Giussy Barbara, Fabio Parazzini, Alessandra Kustermann. Effects of SARS Cov-2 epidemic on the obstetrical and gynecological emergency service accesses. What happened and what shall we expect now? European Journal of Obstetrics & Gynecology and Reproductive Biology, Volume 254, 2020, Pages 64-68, ISSN 0301-2115, https://doi.org/10.1016/j.ejogrb.2020.09.006.&nbsp;

Paper 6 – four maternal deaths from suicide & two women murdered during UK lockdown

Four women died from suicide during pregnancy or soon after birth and two recently pregnant women died from domestic violence in the UK, between 01/03/2020 and 31/05/2020,causes (click here or ref.-201-mbrrace-uk-maternal-covid-19-report-final-002)). Citation: Knight M, Bunch K, Cairns A, Cantwell R, Cox P, Kenyon S, Kotnis R, Lucas DN, Lucas S, Marshall L, Nelson-Piercy C, Page L, Rodger A, Shakespeare J, Tuffnell D, Kurinczuk JJ on behalf of MBRRACE-UK. Saving Lives, Improving Mothers’ Care Rapid Report: Learning from SARS-CoV-2-related and associated maternal deaths in the UK March – May 2020 Oxford: National Perinatal Epidemiology Unit, University of Oxford 2020.

Paper 5 – no change in extremely preterm births during lockdown in the SafeBoosC-III consortium trial centres

In this Medxiv preprint the rate of extremely preterm births (<28 weeks) in 46 neonatal intensive care units participating in the SafeBoosC-III trial, did not alter during the three months of most rigorous lockdown, compared with the corresponding three months of 2019 (click here or 2020.10.02.20204578v1.full). Citation: Marie Isabel Rasmussen, Mathias Luehr Hansen, Gerhard Pichler, Eugene Dempsey, Adelina Pellicer, Afif EL-Khuffash, Shashidhar A, Salvador Piris-Borregas, Miguel Alsina, Merih Cetinkaya, Lina Chalak, Hilal Ozkan, Mariana Baserga, Jan Sirc, Hans Fuchs, Ebru Ergenekon, Luis Arruza, Amit Mathur, Martin Stocker, Olalla Otero-Vaccarello, Tomasz Szczapa, Kosmas Sarafidis, Barbara Krolak-Olejnik, Asli Memisoglu, Hallvard Reigstad, Elzbieta Rafinska-Wazny, Eleftheria Hatzidaki, Zhang Peng, Despoina Gkentzi, Renaud Viellevoye, Julie De Buyst, Emmanuele Mastretta, Ping Wang, Gitte Hahn, Lars Bender, Luc Cornette, Jakub Tkaczyk, Ruth del Rio, Monica Fumagalli, Evangelina Papathoma, Maria Wilinska, Gunnar Naulers, Iwona Sadowska-Kakrawczenko, Chantal Lecart, Maria Luz Couce, Siv Fredly, Anne Marie Heuchan, Tanja Karen, Gorm Greisen Extremely preterm infant admissions within the SafeBoosC-III consortium during the COVID-19 lockdown  medRxiv 2020.10.02.20204578; doi: https://doi.org/10.1101/2020.10.02.20204578

Paper 4 – fall in very & extremely low birthweight infants during lockdown in Limerick, Ireland

The rate of birth of both very low birthweight and extremely low birth weight infants reduced significantly in Jan-April 2020 compared witht the same period over the preceding 10 years (click here or e003075.full). Citation: Philip RKPurtill HReidy E, et al Unprecedented reduction in births of very low birthweight (VLBW) and extremely low birthweight (ELBW) infants during the COVID-19 lockdown in Ireland: a ‘natural experiment’ allowing analysis of data from the prior two decades. 

Paper 3 – halving of hospital births & increased perinatal mortality during lockdown in Nepal

Between Jan 1 and May 30, 2020, births in nine hospitals in Nepal halved during the latter 5 lockdown weeks, and stillbirths and neonatal mortality rose significantly (click here or PIIS2214109X20303454 (1)). Citation: KC, Ashish et al. Effect of the COVID-19 pandemic response on intrapartum care, stillbirth, and neonatal mortality outcomes in Nepal: a prospective observational study. The Lancet Global Health, Volume 8, Issue 10, e1273 – e1281

Paper 2 – fall in extreme prematurity during lockdown in Denmark

Using a national database the numbers of extremely premature singleton births was significantly lower between 12 March and 14 April 2020 than the previous five years (click here or fetalneonatal-2020-319990). There was no significant difference in other gestational age categories. Citation: Hedermann G, Hedley PL, Bækvad-Hansen M, Hjalgrim H, Rostgaard K, Poorisrisak P, Breindahl M, Melbye M, Hougaard DM, Christiansen M, Lausten-Thomsen U. Danish premature birth rates during the COVID-19 lockdown. Arch Dis Child Fetal Neonatal Ed. 2020 Aug 11:fetalneonatal-2020-319990. doi: 10.1136/archdischild-2020-319990. Epub ahead of print. PMID: 32788391; PMCID: PMC7421710.

Paper 1 – rise in stillbirths at a London hospital

St George’s hospital in South London noted a rise in stillbirths between February 1 & June 14, 2020 compared with the previous four months (click here or jama_khalil_2020_ld_200076). Neonatal deaths were not reported. There were no significant differences in preterm birth rates. Citation: Khalil A, von Dadelszen P, Draycott T, Ugwumadu A, O’Brien P, Magee L. Change in the Incidence of Stillbirth and Preterm Delivery During the COVID-19 Pandemic. JAMA. 2020;324(7):705–706. doi:10.1001/jama.2020.12746

Jim Thornton, Keelin O’Donoghue & Kate Walker

Beth Rowley

September 27, 2020

Supporting artists during lockdown

   

If your spine tingled to the introductory music to the BBC drama Strike (click here) you’re a Beth Rowley fan. She comes from my birthtown, Bristol, and has released two albums. I think she’s right up there with Adele and Amy Winehouse. But it was through Strike that I discovered her. Normally I’d have played her on Spotify and checked if she ever performed near Nottingham. But she won’t be touring now.

Until streaming came along, musicians used to make most of their money from LP & CD sales. Then live performance took over, surely a good thing.  Now that has stopped we need to go back to buying CDs. Her latest Gota Fria is £11.99 on Amazon, and an extra 95p on her own website. I love Amazon but they are doing well out of lockdown. I still have a job and less to spend my money on, so the latter it was (click here).

It’s a wonderful record. Time to buy Little Dreamer.

Jim Thornton

OASI care bundle evaluation project

September 23, 2020

A well-conducted study, but an unclear result

I admit it. I was sceptical. A stepped wedge (type of cluster) trial evaluating a “care bundle” (leaflets, a manoevre called the “Finnish grip”, 60o episiotomy & routine rectal examination) with, at best, a shaky evidence base (click here & here), evaluated by researchers who clearly already believed in it, and driven by two political organisations (RCM & RCOG) whose leaders felt that “something must be done” and were claiming success even before it started (2016 links no longer available). When the project ended, and more press releases announced success (2018 links not available), without any results appearing for over two years, I feared the worst; sample size changes, centres excluded for “low compliance”, participants disappearing from analysis groups, outcome switching, statistical shenanigans.

The “Finnish grip” is a bit odd too. Although mentioned on the Care Bundle website (click here), it doesn’t appear in the protocol or trial registry – I did a word search. Both call the 3rd element “Manual perineal protection”. The “Finnish grip” is mentioned, but not described, in the main trial report, and the references cited as sources (click here and here) describe it as “a technique for guiding the head through the introitus by gripping the baby’s chin with a flexed middle finger of the other hand”. They both refer to (Pirhonen et al 1998 click here) as the original source. In 1998 Jouko Pirhonen was a trainee in Lund, Sweden, and he is now a professor in Oslo, Norway. But Pirhonen is a Finnish name, and his co-authors included three obstetricians (no midwives) from Finland. They wrote:

“The delivery assistant presses the baby’s head with her left hand to control the speed of crowning through the vaginal introitus. Simultaneously, using the thumb and index finger of the right hand to support the perineum while the flexed middle finger is used to take a grip on the baby’s chin. When a good grip has been achieved, the woman is asked to stop pushing, to breathe rapidly, while the midwife slowly helps baby’s head through the vaginal introitus. When most of the head is out, the perineal ring is pushed under the baby’s chin.”

This is anatomically impossible, unless the flexed middle finger enters the rectum – surely they don’t mean that! – and even then it would be a stretch to reach the chin. Something probably got lost in translation. In practice it’s likely that midwives using the Care Bundle controlled delivery of the head by perineal pressure and discouraging maternal pushing.

I confess I feared the whole study would shed more heat than light on the topic, and together with a colleague, Hannah Dahlen, wrote a grumbling opinion piece (click here).

But the results are in (click here or gurol-urganci), together with a qualitative study of the implementation process (click here or bidwell), and I’m eating my words.

The study was registered (click here), and the protocol published (click here). Registration was a bit late 22/09/2017 – the project ran from 1 October 2016 and 31 March 2018 – but that’s made clear in the paper, and the protocol had been publicly available since January 2017. There’s no reason to believe either was written after peeking at the data.

Four regions, each containing a mixture of different size and type of birth unit were studied over the same 18-month period, with routine data collected all through. Only four randomised units is rather few, but unavoidable due to funding contraints.

Regions were randomised to have the care bundle taught and implemented sequentially over months 4-6, 7-9, 10-12 or 13-15 respectively. These transition periods were excluded from analysis. This left four 3, 6, 9 or 12-month duration baseline phases, and four same duration evaluation phases to compare. The Consort flow diagram, for some reason relegated to supplementary material* (click here), shows the design nicely. Exclusions were all for objective reasons, Caesarean, multiple or still-birth and did not alter over the trial.

All women having a singleton vaginal birth were included and the size of the before and after groups was approximately equal (baseline 27,668, evaluation 27,932). This is reassuring. Differential rates of Caesarean birth, baseline 12,807 (31.6%) v evaluation 12,472 (31.3%), had not muddied the waters.

The primary, indeed the only, endpoint was OASI (obsteric anal sphincter injury) as recorded on the hospital routine database, and the primary analysis was done after statistical adjustment for a range of potentially relevant factors. Here are the relevant methods as reported in the paper.

“We used multi-level logistic regression to estimate adjusted odds ratios (aOR) […]. The regression model included a linear term for calendar time […] a random effect to account for clustering at both region and unit levels and individual case-mix factors (maternal age, ethnicity, body mass index, parity, mode of birth and birthweight).”

And here they are as planned in the protocol.

“We will use logistic mixed effects regression to model the log odds of sustaining an OASI, with a fixed effect for each step and a random effect to account for clustering at the unit level. The model will include a linear secular trend and also adjust for risk factors for OASI (maternal age, BMI, ethnicity, mode of delivery, episiotomy, birthweight, prolonged labour, and shoulder dystocia).”

Perfect. The planned analysis was done.

And the result. The recorded OASI rate decreased from 911/27,668 (3.3%) baseline phase to 817/27392 (3.0%) evaluation phase (aOR 0.80, 95% CI 0.65–0.98) p=0.03.

But what does it mean? Did manual perineal protection prevent 94 women suffering OASI? Did the 60o episiotomy do the trick? Did a few women read the leaflet and, fearful of OASI, choose Caesarean? Or a mixture of all three? Or was the difference in the “diagnosis” of OASI?

The original research, which had inspired the trial, had shown a much larger increase in recorded OASI from 1.8% in 2000 to 5.9% in 2011 (click here). The authors of that study, who included many of the current trial authors, had concluded that “improved recognition of tears following the implementation of a standardised classification of perineal tears was the most likely explanation”. They were surely correct. Diagnosing OASI is not easy. It can be both over and underdiagnosed. An effect size of 0.3% in an endpoint which can vary by 4.1% due “improved recognition” must be susceptible to ascertainment bias.

And this was an “open” trial. Staff may not have realised they were in the baseline phase but they certainly knew about the implementation and evaluation phases. This is from the qualitative study report (click here or bidwell).

“Many participants spoke about a well advertised launch, which created a lot of ‘noise’ and got the project off to a good start: ‘Yes, we had a launch day at the unit….on that day they had many sessions talking about it. We had the models.….they had pictures of how you would give an episiotomy, things like that, to add to this…There was quite a lot of noise about this. (Midwife)'”

“Many talked about the positive and passionate way with which the champions delivered the training. ‘She [the champion] was like a hound! …. if you weren’t trained and you were on her list, she would hunt you down….She would come in early to catch people on night shifts and stuff……If you have somebody like that who is passionate about the training and gets the training done, then I think that’s what makes it better. (Obstetrician)'”

How did midwives and doctors in the midst of such a campaign classify borderline cases?

Consider, for example, a woman with suspected OASI transferred to the operating theatre for repair, who when reviewed under good light by a senior staff member was found to have an intact sphincter? Would the theatre staff recode the planned operation to “repair of episiotomy”? In the baseline phase they might not even have realised the diagnosis had changed. But in the implementation and evaluation phases, with champions “hounding” everyone, the coding surely would be altered. Of course the effect might also have gone in the other direction. Routine rectal examination might have increased diagnosis. We just don’t know.

These doubts matter because the underlying evidence base for each component of the bundle is so weak. Well designed individually randomised trials do not support manual perineal protection (click here), there have been no trials of 60o angle episiotomy, and rectal examination after normal birth in the absence of a tear makes no sense (click here).

We can all support information giving, avoiding midline episiotomies and doing rectal examinations in the presence of tears. But the debate over manual perineal protection, extremely lateral episiotomy, and routine rectal examination even after normal birth with an intact perineum, will surely continue.

Jim Thornton

Footnote. *The Consort flow diagram belongs in the main report, especially for complex designs. Come on BJOG!

An improved martini

September 4, 2020

Not a better recipe, but a better technique – freezing water in the glass

Last week, dipping into Kingsley Amis’s Everyday Drinking (click here) on holiday, I came across this under “the Dry Martini”.

“A couple of hours before the party get your glasses together. They should be on the small side – the second half of a too large martini will have become too warm by the time the average drinker gets to it – and have some sort of stem or base to prevent the hand-imparting warmth. […] Fill each with water and put in the refrigerator.”

I read it as “put in the freezer”. As Amis says.

“It is more important that a cold drink should be as cold as possible than that it should be as concentrated as possible.”

I should have realised that in Amis’s day the freezer section of a domestic fridge would barely hold a tray of ice; no chance even a small martini glass. But I’ve got a modern monster freezer, so undaunted I made my martini. Freezing the water in the glass in emulation, and using a modern vermouth, Regal Rogue – Daringly Dry (click here), to annoy him. Click here for the video. It worked a treat.

    

Only afterwards did I realise he’d never meant “freeze the ice in the glass”. He wrote.

“While the jug is standing, empty the water out of the glasses and drop a bit of lemon rind in each.”

Nor, from a brief google search, does anyone else. People add ice cubes, sometimes large ones to avoid the over-dilution problem, but never my technique.  I offer it to the world.

Jim Thornton

6 September update

I was wrong, or rather right first time. Amis did advocate freezing water in the glass, albeit ten years later. My volume is a compendium of three books; On Drink (1974), Everyday Drinking (1983) and How’s Your Glass? (1985). The quotations were from On Drink. By the time of Everyday Drinking he must have got a larger freezer. He writes.

“The best Dry Martini known to man is the one I make myself. In the cold part of the refrigerator I have a bottle of gin and a small wineglass, half full of water that has been allowed to freeze.”

“When the hour strikes I half fill the remaining space with gin, flick in a few drops of vermouth and add a couple of cocktail onions, the small white hard kind. Now that is a drink.”

Oh well. Nothing new.

Lockdown cocktails

July 13, 2020

Drinking – not paddling – down the Loire

Our small gang have been walking the Camino de Santiago (click here or here), and more recently canoeing the Loire (click here or here). When lockdown put paid to our 2020 trip from Blois to Saumur we met up on Zoom instead, and inspired by Stanley Tucci (click here and here), drank cocktails. Here they are; some with a poem.

Hemingway’s daiquiri (click here).

Philip Larkin’s gin & tonic (click here).

A “No”groni (click here).

A conventional Negroni under adverse conditions (click here).

James Bond’s Vesper martini (click here).

The Gilles Villeneuve martini (click here).

A Radish Walked into a Bar (click here)

The Kingsley Amis martini (click here).

Forgive the rough edges. Filmed on different phones, and once made you’ve gotta drink it, so a second take wouldn’t help.

We also drank appropriate wine from the brothers Yapp, but no videos of that. First day sweet Vouvray (click here), 2nd a dry one (click here), 3rd Bourgueil (click here), 4th Saint-Nicolas-de-Bourgueil (click here) and 5th Saumur (click here). Forgotten the others, but to end with, we popped open a fizz (click here). All more expensive than our usual riverbank plonk, but I guess we’d saved on the ferry crossing. 

Lockdown 2

First zoom cocktail for lockdown 2, the Brexitini (click here).

The Euro martini (click here).

The Roman Moselle citrus sangria a la Kingsley Amis (click here).

Susie’s negroni (click here).

A Moselle martini with a nod to Michael Portillo (click here).

A French sidecar (click here).

A real martini (click here).

Whisky sour with a fairy egg (click here).

Third wave staycation

Dark & Stormy (click here).

Pornstar – hard and softcore (click here).

Tequila sunrise (click here). Ignore my claim to be making a Mojito!

This one really is a Mojito – plenty of mint! (click here).

Jim Thornton

Wild swimming in the river Trent.

June 6, 2020

Downstream of Nottingham

One of my projects for the 2020 lock-down summer has been to swim the best spots. If you don’t mind disclaimer forms, safety briefings, and signing in and out [1], there’s a dedicated centre on Colwick Park lake (click here). But that’s not for me. For swimming spots in the gravel pits click here.

These swims are for privateers. Only East Stoke, Stoke Wharfe, Farndon and Holme are on the right, south/east bank. Update 16 June 2020 – Cromwell. 1 June 2021 – two right (south) bank spots, East Stoke and Stoke Wharf added. 25 July 2021 – Stoke Bardolph revised. 5 August 2022 – Holme added

Stoke Bardolph – Left bank 

Right in front of the Ferry Boat pub, two or three slipways and landing stages provide easy access. Crowded on sunny days. Alternatively follow the first straight section of the metalled riverside path upstream towards Bardolph weir; many good gravelly entry points.

Stoke Bardolph is about 100 yards upstream of the discharge from Severn Trent’s, state of the art, treatment plant. Upsteam’s good!.

Gunthorpe – Left bank

Park in front of the Unicorn Hotel, and swim off the metal boat ramp next to the water ski club.

      

Don’t forget Gunthorpe gravel pit. Some fishermen claim swimming is prohibited there, so be discreet. Walk under the road bridge for about 1/2 mile, and turn right immediately after footbridge. Lots of easy access and a lovely stony bed. Magical.

 

Hoveringham – Left bank 

On sunny days the parking along the river bank road gets full early, but the bank is stony and access easy. Any slight smell is from muck-spreading on the surrounding fields, not the river.

Hazleford – Left bank 

One of my favourites. The metal slipway at the end of the road provides easy access, albeit slippery. The car park is private and locked, but there’s plenty of space on the road. The boat moorings leave a sheltered area near the slipway for those who are nervous of venturing into midstream.

If the slipway’s crowded try upstream, along the river path, past the moorings and caravan park. Plenty of the fishing pegs have good access. I swam by the Km 23 mark.

Downstream less good. Although plenty of access below the weir, the water tends to be frothy.

East Stoke – Right (south) bank. New 2021

Travelling south from Farndon, on the old A47 (Fosse Way), turn right into East Stoke and follow the unsurfaced road past Stoke Hall, all the way to the river opposite Fiskerton. Ample parking and a good path to a rickety wooden stage. Muddly, but the stage helps your balance. On sunny days an audience from the Bromley Arms opposite.

Fiskerton – left bank

Park about 1/4 mile downstream of the Bromley Arms and walk upstream. The problem here is the high river wall. Don’t even think of jumping! Some pontoons are barred off, and they all have “private mooring” signs, but no-one has ever objected to me using one of the open ones. Getting back on is tricky. Swim round to the river wall – shallow stony bed – and step back on with your dignity intact.

        

Peg 18 below Fiskerton – left bank

Park as above and walk downstream. Nottingham Piscatorial Society have marked their fishing pegs with numbers set in the grass. Peg 18’s label is obscured but it’s the best spot. If you avoid the fishing season, usually quiet enough for a skinny dip.

Stoke Wharf – Right (south) bank. New 2021

Midway between Farndon and East Stoke on the Fosse Way, a barred, field entrance has room to park. Fifty yards from the road, each fishing peg has beautiful stone steps providing easy access. Peg 13 for me! Outside of the bend but I just about made headway against the current. The downstream pegs provide easy exits for weaker swimmers. A lovely private spot.

Note added 15 April 2023. An anonymous person calling themselves Secretary Newark Federation has written, “Please be aware that our land at East Stoke is private and says so on the locked gate, which you mention in your description, anyone found parking or swimming will be reported to the police.”

Farndon – Right (South) bank

From the roundabout at the south end of Newark bypass, take the B166, the old Fosse Way to Farndon. Turn right, then left, initially following signs to Farndon marina. Ignore the 2nd right to Farndon marina and follow signs to The Waterfront. Sandy ramp. Lovely.

North Muskham – left bank

Down Ferry Lane to the Muskham Ferry pub, and swim off the slipway.

Holme – right bank (New 2022)

Opposite the Admiral Nelson in Winthorpe follow signs to Holme. Over level crossing, and left at T junction. Footpath from village centre leads to some good spots opposite, and a few hundred yards downstream, of Muskham Ferry. But there were cows and fishermen about, and I had a dog.

Alternatively turn right in Holme, and park at the end of the road. Follow the track downstream, past the active gravel pits right, with their “deep cold water” and “danger of death” signs. About 500 yards upsteam of the weir was very isolated. Perfect for a skinny dip.

Cromwell – left bank

A farm track, signed as a footpath, from Cromwell village, crosses the A1 as a single track road to the lock. Plenty of parking at the sign which says “no parking or boat launching at the lock”. Upstream of the lock, by two brick barbeques, a ramp leads to a pontoon with steps into the water at each end. Perfect.

Carlton-on-Trent – left bank

Head for the Church, and Ferry Lane. The road to the river, Perry Lane, is full of “no access to river” signs so I parked back up in the village. In fact there is parking. Two possible swim spots. Upstream of the commercial wharf, access looks easy via stony muddy banks, but I was nervous of a metal detectorist on the opposite bank.

The wharf itself has a ladder down to the water, but it’s high and muddy and my courage failed again. About 1/4 mile downstream is best. Stony and a bit muddy, but a good gap in the nettles. The opposite bank also looked inviting.

Carlton is downstream of Cromwell weir, so right at the tidal limit. But it’s on the outside of the bend so you’re straight into fast flow. I kept station, but only just. If you got carried downstream, you’d end up clambering out through nettle beds.

I’ve never swum below Carlton. There must be good spots but I doubt they beat the ones above.

Jim Thornton

Footnote

  1.  One of the annoyances of river swimming is people banging on about the risks. Learn to swim and avoid the river in spate or near weirs. Weil’s disease is rare; only about 30 recreational cases, and less than one death, per year in the UK. Given the number of people coming into contact with river water, the drive to the riverbank is probably more risky, but avoid swimming with an open cut. Gastroenteritis is less of a risk for us older swimmers who don’t wear wet suits, don’t stay in so long, have developed antibodies and are wise enough not to swallow.

Covid-19 pregnancy news reports

May 17, 2020

Primary newspaper sources

In roughly reverse order. Updated regularly. Click here for ripe-tomato.org’s Covid-19 in pregnancy navigation page. From 14 January “Vaccine in pregnancy news reports” included. For access to those US sites which are blocked in the EU, not many, I use https://www.proxfree.com/ 

Reports referring to primary scientific sources, and reports using only semi-quatitative adjectives, e.g. “some”, “many”, “surge in” cases, excluded.

Note – numbering error 319 to 520. The total number of reports are 200 fewer than the latest number would imply.

4 April

1294. Tamara Grieve from South Gippsland, Australia, contracted Covid late in pregnancy (click here). She gave birth and has recovered. Report 1 April

1293. Rachael Fogarty, 29, from Liverpool, contracted covid and gave birth by C-section on 27 November (click here). Mother and baby recovered. Report 4 April

1292. Charma Jonathas, 35, from Port St. Lucie in Florida, contracted Covid and gave birth on Aug. 19 at Cleveland Clinic Martin North Hospital in Stuart (click here). She required ECMO at Palm Beach Gardens Medical Center and recovered. She had not been vaccinated, and has continued to decline vaccination. Report 30 March

1291. Courtney Seddon, 28, tested positive and gave birth by Caesarean at Auckland City Hospital on 25 March (click here). Report 30 March

1290. Sarah Marechaux, from Fintona, Northern Ireland, contracted Covid in October 2021 (click here). She gave birth via C-section on October 23, 2021, at the South West Acute Hospital, Enniskillen. She was seriously ill but recovered, and was finally discharged home in January 2022. Report 28 March

19 March

1289. 30% of women giving birth in Middlemore hospital, Aukland, New Zealand between February 28 and March 8 were infected (click here). For Aukland district overall the figure was 20% (click here). Report 17 March

18 March

1288. Rowena Salas contracted Covid in November 2021 and gave birth prematurely at Southern Hills Hospital in Las Vegas, Nevada (click here). Shortly after,birth she was transferred to Sunrise Hospital for ECMO. She recovered and went home on March 3rd, 2022. The baby also recovered. Report 15 March

1287. Betsy Bloch contracted Covid on Christmas Day 2020 and was delivered by Caesarean at about seven months gestation, at UnityPoint-Meriter Hospital in Madison, Wisconsin, early in 2021 (click here). Post natally her condition deteriorated, due to a fungal lung infection, blastomycosis, and she was transferred to University of Wisconsin Health Hospital for ECMO. She eventually recovered and went home in March 2021. The baby recovered. Report 14 March

1286. Mona Rehman, 41, from Sheffield, contracted Covid in January 2021, at 28 weeks, and gave birth at 29 weeks by Caesarean (click here). She required 4 days ventilation, and her baby a prolonged stay in NICU. Both recovered. Report 14 March

11 March

1285. Arkansas reality TV personality, Jill Duggar, tested positive during her pregnancy (click here). The pregnancy is ongoing. Report 10 March

8 March

1284. Ana Perez-Arietta, 33, from New Brunswick contracted Covid and gave birth at Temple University Hospital in Philadelphia soon after (click here). She died two months later in February. Report 7 March

1283. Queensland Senator, Nita Green, from Cairns, Australia, got vaccinated while pregnant and gave birth on 1st March (click here). Report 3 March Vaccine in pregnancy news report

1282. Min, 31, who only gave her surname, from Yangju, Gyeonggi Province, South Korea tested positive two days before her Cesarean delivery at Gachon University Gil Medical Center (click here). Another unnamed woman in her 30’s gave birth on the way to hospital on Feb. 15, while being nursed at-home for COVID-19 when labor began unexpectedly. Report 8 March

1281. Reality star, Lateysha Grace, 29, tested positive for covid, developed pre-eclampsia, and was delivered at 34 weeks (click here). Report 5 March

1280. Harry Potter star, Jessica Cave, 34, has contracted Covid while pregnant and been admitted to hospital (click here). She is in the third trimester and the pregnancy is ongoing. Report 6 March

4 March

1279. 214,000 babies have been born to Covid infected mothers in the Indian state of Telangana since March 2020 (click here). The source is given only as “officials”. Report 2 December

1278. Reality TV star, Jinger Duggar, contracted covid post-natally in December 2020 (click here). She now has long Covid. Report 2 December

23 February

1277. Danakelly Taylor, 24, contracted covid and gave birth 31 weeks and four days by caesarean on August 4, 2021 at Royal United Hospital in Bath, UK (click here). She recovered but her baby died. Report 22 February

1276. Rekha Ramesh from Bengaluru contracted covid at 24 weeks (click here). She gave birth by Caesarean at 24 weeks at Aster CMI hospital. The baby weighed 500g. Both mother and baby recovered. Report 23 February

1275. McKenzie McCombs, 26, from Utah, contracted severe Covid at 28 weeks (click here). She required delivery by caesarean and prolonged ventilation. Both her and the baby survived. Report 22 February

19 February – NR 1237 updated

1274. 34 pregnant women have died from Covid in Namibia (click here). Report 16 February

1273. Erin Zanza got vaccinated at 37 weeks and gave birth normally (click here). Report 14 February Vaccine in pregnancy news report

1272. Tracey Leonard contracted Covid in mid December 2021, and gave birth on 30 December at 24 weeks (click here). Mother and baby survived. Report 15 February

1271. Macenzee Keller contracted Covid in November and gave birth by Caesarean on 28 November at Catholic Medical Center, Manchester, New Hampshire (click here). Her condition deteriorated and she was transferred for ECMO at Dartmouth-Hitchcock Medical Center. Two month later she recovered. She had not been vaccinated. Her baby is fine. Report 18 February

12 February

1270. Kelly Stanfield, 36, from Cypress, Texas, contracted covid and gave birth at 27 weeks by Caesarean (click here). She was severely ill, but her and the baby both recovered. Report 23 September 2021

11 February

1269. Courtney Thomas, 38, contracted covid and gave birth to her first child at Medical City McKinney, Texas, at 36 weeks in early October 2021 (click here). She spent a month on a ventilator but recovered. Her baby is fine. Report 10 February

1268. Tp date 10,591 nursing mothers, and 2,476 pregnant women, have been vaccinated in Almaty, Kazakhstan (click here). Report 11 February. Vaccine in pregnancy news report

1267. Ali Hair got vaccinated while pregnant and gave birth normally (click here). Report 11 February Vaccine in pregnancy news report

1266. Stephanie Baker, 31, of Shallotte, North Carolina, contracted Covid and delivered twins by Caesarean on January 27. She died on Jan 30 (click here). She was unvaccinated. One twin was stillborn. The other survived. Report 10 February

1265. Rhian Thompson got vaccinated while pregnant (click here). She gave birth normally in October 2021. Report 11 February Vaccine in pregnancy news report

7 February

1264. An unnamed woman with severe Covid was delivered at University of Louisville Hospital in October 2021 at 24 weeks (click here). The mother was treated with ECMO. She had not been vaccinated. Report 6 February.

1263. Over the whole pandemic 1,800 women with covid have given birth at Ghandi Hospital in Hyderabad (click here). 700 by Caesarean. There are currently 35 Covid-19 infected pregnant women in the hospital. Report 7 February

1262. Nicole Fahey, Kate Yohay, and Caroline Fiore all got got vaccinated while pregnant (click here). Report 7 February Vaccine in pregnancy news report

6 February

1261. One unnamed woman with Covid, at Derriford hospital, Plymouth, was told her baby had died (click here). Four other pregnant women in the same hospital have required intensive care during the pandemic. None died. Report 2 February.

1260. Agnieszka T, contracted covid in December 2021 while pregnant with twins and the fetuses died shortly afterwards. She died on Jan. 25 at a hospital in Czestochowa, allegedly due to medical failure to do an abortion (click here). Report 31 January

1259. Linsey Taylor, from Topeka, Kansas, tested positive at 28 weeks, shortly before discovering her baby had died in-utero (click here). Report 3 February

1258. An unnamed woman with Covid gave birth at 30 weeks at the Jewish General Hospital, Montreal (click here). Her condition deteriorated and she is now on ECMO at McGill University Health Centre – Montréal. She had not been vaccinated. Her baby is in PICU at Montreal Children’s Hospital. Report 30 January

1257. Samantha Reyna, 21, contracted mild Covid at term and gave birth at DHR Health Women’s Hospital in McAllen, Texas (click here). Her baby was isolated from her. She was unvaccinated. Report 2 February

1256. Paige Dempsey, 46, contracted Covid in Feb 2021, early in pregnancy (click here). She recovered, later got vaccinated, and gave birth normally at term. Libby McDowell, 36, also contracted Covid during pregnancy in July 2021. She recovered and delivered twins in December at Omaha’s Methodist Women’s Hospital. In the same report two unnamed women died of COVID while pregnant in Nebraska. Report 4 February

1255. Jenny Gooch, 31, from Moore county, North Carolina, contracted Covid in Spring 2020, at 23 weeks and went into preterm labour (click here). She recovered, but her baby died aged one month. Report 3 February

2 February

1254. Diana Crouch, 28, contracted covid in August 2021 (click here). At 18 weeks gestation she was transferred to Texas Children’s Hospital, and placed on ECMO. At some point she suffered strokes, a heart attack and seizures.  She gave birth via caesarian section at 31 weeks. She went home on December 28, 139 days following her admission. She had not been vaccinated. The baby survived. Report 2 February

1 February – update for NR 1145

1253. Jess Eva, 37, the host of Sydney radio show, Triple M, contracted Covid while early in pregnancy towards the end of 2021, and miscarried soon after (click here). Report 31 January

31 January

1252. From 1 to 20 January, 261 pregnant women contracted the virus in the Tokyo metropolitan area, about a 50-fold increase on the previous month (click here). On 28 January the San-Ikukai Hospital in Sumida Ward, Tokyo, was caring for nine pregnant patients infected with the coronavirus. At Chiba University Hospital in Chiba City, two beds reserved for pregnant women with the coronavirus have been occupied most of the time since the middle of January. There were no infected pregnant women in the prefecture from October to December. As of Jan. 20, however, the prefecture had registered about 50 such individuals, many of whom were recuperating at home. Report 30 January

1251. Leah Moyer, 25, from Mayfield, contracted covid and gave birth by Caesarean (click here). Post natally her condition deteriroated and she required ECMO at Baptist Health Paducah, in West Kentucky. Her baby tested negative. Both recovered. Report 30 January

1250. Italian Reality star, Alessia Macari, 26, tested positive and gave birth the following day (click here). She had been vaccinated. The baby tested negative. Both recovered. Report 30 January

28 January – report 1235 updated.

1249. The FIASO survey conducted in 12 sentinel hospitals (incl. Asst Civilian hospitals of Brescia, Irccs San Martino Polyclinic Hospital of Genoa, Irccs Aou of Bologna, Tor Vergata Polyclinic, San Giuseppe Moscati Hospital of Avellino and Bari Polyclinic) included a number of pregnant women with Covid (click here for January 5 or here for the week 18 to 25 January). [Note – I cannot find a link to the primary report] Reports 12 and 28 January

1248. Cheyenne Lewis, from Tyndall Airforce base in Florida, gave birth normally in August 2021, but contracted covid three days later while in hospital (click here). She recovered and the baby was not infected. Report 26 January

1247. Kristen Miranda, 29, contracted severe Covid on 1 Jan and gave birth at Southern Hills Hospital, Las Vegas, on 5 Jan, at 31 weeks (click here). Both mother and baby survived. Report 22 January

1246. Hollie Bourne, 23, from Folstone, Kent, contracted Covid at term and gave birth at home on 23 July (click here). Her baby was stillborn. Report 26 January

1245. Yide contracted covid and gave birth on 28 January. Her baby died the next day (link here not working on my proxy).

1244. Nikki Paterson, from Dalgety Bay, Scotland, contracted covid during pregnancy, recovered, and gave birth normally at 38 weeks (click here). Report 24 January

1243. Kara Bennett tested positive shortly before giving birth to twins by Caesarean at Spectrum Health, West Michigan (click here). In the same report Theresa Sayles tested positive and gave birth normally. Both mothers and all three babies survived. Report 26 January

1242. Nimalla Lalamma, from Banala in Balmoor mandal, gave birth normally outside the Government Area Hospital, Achampet, near Hyderabad having been refused admisssion because she had tested positive (click here). Report 26 January

1241. Ariel Romero gave birth on 25 December 2021 at Medical City McKinney, Dallas, Texas, after 93 days in hospital including a month on a ventilator with covid (click here). She had not been vaccinated. Her baby weighed 5 pounds 9 ounces. Both are recovering. Report 25 January

1240. Cara Jamieson, a Scottish breastfeeding specialist, got vaccinated while pregnant and her booster while breastfeeding (click here). Report 27 Janurary Vaccine in pregnancy news report

1239. Michaela Dailey from Kentucky contracted COVID-19 in late August at 33 weeks gestation (click here). She was delivered by Caesarean. and require ECMO at Hardin Memorial hospital. She had not been vaccinated. Mother and baby recovered. Report 26 January

1238. Billie Cowie, 25, tested positive shortly after giving birth by Caesarean due to pre-eclampsia, at Aberdeen Royal Infirmary (click here). Mother and baby recovered. Report 28 January

27 January

1237. Alexandra Chandler contracted Covid on 6 January and gave birth by Caesarean soon after (click here). Her condition later deteriorated and she required ventilation. The baby tested positive but is recovering. Report 24 January. Note – the People article implies that the information from the GoFundMe page had not been verified. Update 28 January – click here for corroborated mainstream media story. Further update 19 February – Alexandra Chandler died on 12 February (click here). She was from Fort Hood, Texas. Report 15 February

1236. Michaela Jones tested positive and gave birth by forceps at term at Frankston Hospital, Melbourne, Australia (click here). Her baby tested negative. Report 26 January

23 January

1235. An unnamed woman from Dharmabad in Maharashtra, India, tested positive and gave birth normally in Bhainsa Government Area Hospital (click here). Mother and baby are doing fine. Report 23 January. 28 January update – This English language report names her as Laxmibai (click here). Report 23 January

1234. Two unnamed pregnant women with covid are being treated at Milton Cato Memorial Hospital in Kingstown, St Vincent & the Grenadines (click here). Report 22 January

1233. An unnamed 26-year-old woman with Covid gave birth by Caesarean at 30 weeks in Malaga, Spain, and died soon after (click here). She had not been vaccinated. The baby survived. Report 22 January

1232. Two unnamed women tested positive and gave birth normally in Huzurabad Area Hospital in Karimnagar district, India (click here). Report 22 January

1231. An unnamed pregnant woman contracted covid at 16 weeks and miscarried at Brampton Civic Hospital, in Mississauga, Canada (click here). Report 22 January

1230. Thirteen unnamed pregnant women tested positive in Lucknow, India recently (click here). Report 23 January

1229. Mother of 11, and TikTok star, Veronica Merritt, is due to give birth to her 12th child in April. She contracted covid in December and the pregnancy is ongoing (click here). Report 22 January

1228. Barnes Jewish Hospital in St Louis, Missouri is seeing 37% of pregnant women testing positive during the omicron phase. Only 20% tested positive during the delta phase (click here). Report 21 January

22 January

1227. Jodi Long from Des Moines, Iowa, tested positive at 15 weeks. Her symptoms were mild, she recovered, and the pregnancy is ongoing (click here). She had been vaccinated. Report 21 January

21 January – News report 9 updated

1226. In Trinidad, 58 unnamed pregnant women contracted covid in 2020, 1,101 in 2021, and 22 so far in 2022 (click here). Six unnamed mothers died, one in 2022. In the same report a new-born baby who died as a result of prematurity was a case of mother to child transmission, and as of January 17, 1,084 pregnant women had been vaccinated. Report 19 January

1225. Helen Skelton, the host of Channel 5’s This Week on the Farm, contracted Covid a few days before Christmas and gave birth normally on 28 December, at Leeds General Infirmary (click here). Mother and baby are doing fine. Report 18 January

1224. Kelly Mitchell from Milwaukee, got her booster vaccine in October early in her pregnancy (click here). She is now 4 months gestation and the pregnancy is ongoing. Report 20 January. Vaccine in pregnancy news report

1223. Caitlin Mulligan, 22, contracted Covid, and gave birth at 32 weeks Victoria Hospital in Kirkcaldy, Fife (click here). She recovered but her baby spent 72 days in NICU. Report 20 January

1222. Jo Udeze, 39, contracted Covid at 30 weeks (click here). She gave birth by Caesarean in August at Walsall Manor Hopital and spent two weeks in induced coma in ITU. She and the baby recovered. She had not been vaccinated. Report 20 January

1221. Erem Ali, 29, contracted covid at 31 weeks pregnant. She was delivered by c-section on 2nd February 2021 at Royal Surrey County hospital, Guilford (click here). Her condition deteriorated and she was transferred to St Thomas’ Hospital, Westminster, London. Following many complications she is now home. She had not been vaccinated. Her baby survived. Report 21 January

1220. Crystal Hernandez, 27, contracted covid on 1 Jan at 24 weeks and was delivered by Caesarean on 6 Jan at 25 weeks (click here). She died soon afterwards. Her baby remain in NICU. She had not been vaccinated. Report 20 January

1219. Michelle Stani, 37, died on January 12 at Robert Wood Johnson University Hospital in New Brunswick (click here). She had given birth three weeks earlier. Report 19 January

1218. Sheena Berry, 37, contracted Covid in the 2nd trimester in late August 2021. She spent 2 month on ECMO and 4.5 months in the ICU at Piedmont Hospital in Atlanta (click here). She survived and gave birth to a healthy baby on 14 Jan at 37 weeks. She had not been vaccinated. The same newspaper reports that 15 unnamed pregnant women with Covid have been treated with ECMO at this hospital. One unnamed mother died but all babies survived. Report 18 January

17 January

1217. Alessandra Peluso contracted Covid late in 2021 (click here). She gave birth to premature twins at Santobono Hospital in Naples. She later died. The babies survived. She had not been vaccinated. Report 17 January

1216. Tyarna Hansen, from Ceduna in South Australia, contracted Covid at four months gestation (click here). She is staying in an Adelaide hotel, and the pregnancy is ongoing. Report 17 January

1215. Duangdee Inthachack, 20, a farmer at Nabor Village, Yommalath District, Khammouane Province, Laos, was vaccinated in the seventh month of her pregnancy on 24 November 2021 (click here). In the same report Bo Kaly, 28, got vaccinated in her eighth month of pregnancy on 26 November 2021. Report 17 January Vaccine in pregnancy news report

1214. Rachel, 38, from Bilston in Wolverhampton, contracted Covid while pregnant, was in a coma and in hospital for three and a half months, and gave birth to a stillborn son at 24 weeks in August 2021 (click here). She was cared for at New Cross hospital in Wolverhampton and at Glenfield hospital in Leicester, the regional ECMO unit. She had not been vaccinated. Report 15 January

12 January

1213. An unnamed woman tested positive and was photographed shortly after giving birth in McAllen, Texas (click here). Report 23 December

1212. On one day in December 2021, at the peak of the 4th wave, 13 unnamed women gave birth and tested positive in one unnamed Netcare hospital in South Africa (click here). They were all presumed to have the Omicron variant and all were asymptomatic. Report 7 January

7 January

1211. Eleven unnamed pregnant women with covid are inpatients in one unnamed materity hospital Gothenberg, Sweden (click here). Report 7 January

1210. An unnamed woman in South Korea contracted Covid on December 23, gave birth on December 28 at 32 weeks, and died on 4 January (click here). She had not been vaccinated. The baby tested negative and is not displaying symptoms. Report 7 January

5 Jan 2022

1209. Jemimah Steinfeld contracted Covid and gave birth at 31 weeks in December 2020 (click here). Mother and baby survived. Report 22 November

4 Jan 2022

1208. 6,947 pregnant or postpartum women have contracted Covid in Cuba since the start of the pandemic (click here). Report 3 January

1207. The wife of Pranjal Patowary from Assam, contracted Covid in April 2021, at 12 weeks gestation (click here). The pregnancy continued and she gave birth later in 2021 to a healthy baby. Report 4 January

1206. Annmaree Freeman from Warrnambool, Victoria, Australia, tested positive on 30 December at 31 weeks gestation (click here). Her pregnancy is ongoing. Report 4 January

1205. Holly Eckler, from Wichita, contracted Covid at 25 weeks (click here). She required ventilation and transfer to the University of Kansas Health System, but recovered with kidney damage and an ongoing problem with her voice. She had not been vaccinated prior to contracting Covid, but her experience persuaded her to do so. The pregnancy is ongoing. Report 3 January Vaccine in pregnancy news reports

1204. Halie Mulanax, 16, contracted severe Covid on 29 November, required ventilation, and gave birth in Amarillo, by Caesarean at 29 weeks, on 9 December (click here). She remains on a ventilator at Texas Children’s Hospital in Houston.. She had not been vaccinated. The baby is fine. Report 4 January

1203. Lareesia Wright, 30, from Arizona, died on 25 December, from complications of Covid, four months after giving birth on 27 August at 35 weeks (click here). She had contracted Covid while pregnant and been in a coma ever since. She had not been vaccinated. Report 3 January

1202. Fitness influencer, Tammy Hembrow, 27, contracted mild Covid on 31 December, at 18 weeks gestation (click here). The pregnancy is ongoing. Report 4 January

3 Jan 2022

1201. Two unnamed pregnant women are currently in ITU, but not ventilated, in Queensland Australia (click here). One had not been vaccinated. Report 2 January

1200. Valerie Scalf contracted Covid in the second trimester, recovered, and gave birth at Reid Health Ohio, on 1 January (click here). Report 2 January

1199. An unnamed pregnant woman in Israel has contracted both Covid and influenza and gave birth at the Rabin Medical Centre (click here). Her symptoms were mild. She had not been vaccinated. Report 3 January.

1198. Lakeisha Peterson, tested positive for Covid, and gave birth to twins at 26 weeks at Vidant Medical Center, North Carolina on 1 Jan 2022 (click here). Report 2 January

1197. Maham Irfan, 29, from Dubai, contracted severe covid in July, requiring prolonged ventilation, and gave birth at 27 weeks by Caesarean, at Al Zahra hospital (click here). Mother and baby recovered. Report 3 January

1196. Jessica Powell, 34, from Portsmouth, UK, contracted Covid two weeks ago, recovered, and gave birth normally to a healthy baby on 1 Jan 2022 (click here). Report 2 January

31 December

1195. Emily Robinson contracted Covid and gave birth by Caesarean, nearly two months early (click here). She died a month later at Mercy Hospital, Fort Smith, Arkansas, on 20 Sept. Her baby survived. Report 30 December

1194. Yvonne Khoo, 37, contracted severe Covid on 26 October at 25 weeks (click here). She required six days ECMO at Singapore General Hospital. The pregnancy continued, but after stopping the ECMO she got contractions and the baby was delivered by caesarean on 4 November at 27 weeks. Mother and baby recovered. She had not been vaccinated. Report 31 December

1193. 2003 Pop Idol winner Michelle McManus tested positive on December 30 (click here). Her pregnancy is ongoing. She is due early in the new year. She had been double vaccinated. Report 31 December

29 December – NR 1086 updated.

1192. Montoya Binion, from Alabama, contracted covid and gave birth by Caesarean (click here). She required 16 days ventilation after the birth. Both mother and baby recovered. Report 29 December

1191. Ashley-Marie Carroll contracted Covid in November 2020, at 26 weeks, while in Stoke Mandeville hospital after a car crash (click here). At 28 weeks she developed HELLP syndrome and she was delivered on December 19, 2020. Both mother and baby recovered. Report 25 December

1190. Natalie Forshaw, 30, contracted Covid, and gave birth at Manchester Royal Infirmary on November 3 (click here). She died on 26 December. She had not been vaccinated. Her baby survived. Report 28 December

24 December

1189. Seven unnamed pregnant women tested positive at Lalla Ded hospital in Kashmir (click here). Six are being manged at home, and one was admitted. Report 23 December

1188. Natalie Nielson, from Tullabody, Scotland, contracted Covid at 28 weeks, and gave birth on October 22 (click here). Mother and baby survived. Report 23 December

1187. Tanviha Quraishi-Akhtar contracted covid at 33 weeks gestation in January 2021 (click here). She gave birth by Caesarean at Blackburn Hospital on 9 February, and later ECMO at Wythenshaw hospital. She and the baby recovered. Report 24 December

23 December

1186. On 22 December one unnamed pregnant woman with Covid was about to give birth in Samson Assuta Ashdod Hospital, in Israel (click here). Report 22 December

1185. Bobbie Ann Sison, a nurse at Singing River Health System’s Pascagoula hospital, had an undiagnosed illness in pregnancy, was not tested for Covid, and gave birth on March 3, 2020 (click here). Her baby died of Covid the same day. Report 22 December

22 December

1184. Queshonda Kudaisi, 29, of Winter Haven, Florida, contracted Covid at about 6 months gestation on Aug. 15. She recovered and gave birth on the 8th December (click here). She had not been vaccinated prior to the infection. She received her first vaccination in November. Report 17 December

1183. Kaitlin Moore, from Indianapolis, contracted Covid in September & gave birth at Riley Hospital for Children at 32 weeks (click here). She required 19 days ventilation. She and the baby recovered. She had not been vaccinated. Report 20 December

1182. Jessica Walker, from Monroe, Georgia, contracted Covid on September 12th at 36 weeks (click here). She was delivered by Caesarean and required 39 days ventilation. She and the baby recovered. She had not been vaccinated. Report 20 December

1181. Renee Crutcher, from Detroit, contracted Covid while pregnant, and shortly after giving birth was placed on a ventilator (click here). She died in September after months of treatment. Her baby survived. Report 19 December

1180. Kelli, 26, from Rockford, Illinois, contracted COVID-19, and shortly after giving birth required 21 days on a ventilator (click here). She and the baby recovered. She had not been vaccinated. Report 15 December. 16 Dec update: “The mother reported in this story has disputed the statements made by Brittany Moorman in the interview.”

1179. Jena Davies, 42, contracted Covid and gave birth shortly before term by Caesarean at Dumphries Infirmary on 5 January 2021 (click here). Mother and baby recovered. Report 21 December

1178. Charma Jonathas from Palm Beach Gardens Florida contracted severe Covivid & gave birth in August (click here). She spent months on ECMO in Palm Beach Gardens Medical Center, but she & the baby recovered. Her vaccine status was not reported. Report 21 December

1177. Samantha Montgomery, 31, from Colchester, contracted Covid & gave birth via Caesarean at 27 weeks gestation (click here). She required intensive care, but she & the baby recovered. She had had the first dose of the Astra-Zeneca vaccine in February, before she was pregnant, but not the second. Report 22 December

1176. Chelsie King, 27, from Weston-super-Mare, UK, contracted severe Covid in July 2021, and gave birth via Caesarean, at St Michael’s hospital in Bristol, at six months gestation (click here). She underwent ECMO at St Thomas’s Hospital in London. She and the baby recovered. She had not been vaccinated. Report 22 December

1175. Nicole Bendickson, 30, from Eau Claire, Wisconsin, died on 1 December, twelve days after giving birth to twins (click here). Her husband and her twins had tested positive for COVID-19. It is not clear if she also had Covid. Report 20 December

15 December

1174. Gina Mcguinness, 37, from Hartlepool, UK, contracted Covid at 16 weeks gestation and gave birth normally at term (click here). Report 15 December

14 December

1173. Breann Barber, from Two Harbors, Minnesota, contracted COVID-19 on Nov. 22 and gave birth on Dec 4th at 34 weeks (click here). She and the baby recovered. Report 13 December.

1172. Laura Ward, 33, gave birth by Caesarean at 31 weeks, following which she required 35 days ECMO the Royal Bolton Hospital and later rehabilitation at Wythenshawe Hospital (click here). She and the baby recovered. Report 14 December

11 December – News Report 9 updated.

1171. Krystal Binette, 39, from Fort St. John, British Columbia, contracted Covid at 25 weeks, required treatment with ECMO at the Royal Columbian Hospital in New Westminster, and was delivered by Caesarean on Oct 23rd (click here). She had not been vaccinated. Both her and the baby recovered. Report 7 December

1170. Heather Clark, from Derby, Kansas, died from Covid on 5 December (click here). She had given birth to twins by caesarean late in November Report 8 December

1169. Aimee “Jaqueline” Ayala, 22, from El Paso, Texas, died from Covid on 30 November having given birth by Caesarean at eight months gestation on 13 November (click here). The baby survived. Report 10 December

1168. Sarah Mays, from Loveland, Colorado, got severe Covid, was treated with ECMO and gave birth by Caesarean on August 18, at 29 weeks (click here). Both her and the baby recovered. She had not been vaccinated. Report 10 December

6 December

1167. 995 pregnant, and 3,513 nursing women, have had the Pfizer vaccine in Almaty, Kazakhstan (click here). Report 6 December

1166. Dezi Scopesi, 23, from Utah, contracted Covid in October, when her son was one year old (click here). She died on 2 December. She had delayed vaccination because she was breastfeeding. Report 6 December

1165. Four pregnant women have died from Covid in Tinidad & Tobago (click here). Up to 3 December 1,002 pregnant women had contracted the disease. Report 6 December

1164. Stephanie Sholl, from Columbus, Ohio, got vaccinated while pregnant (click here). She then contracted mild covid at 37 weeks in the same pregnancy. She recovered and gave birth normally at term. Report 6 December

1163. Paige Bliss, 25, from Birmingham, UK, contracted Covid and gave birth by C-section in August, at 27 weeks (click here). She required two days ventialtion but recovered. Her vaccine status was not reported. The baby also survived. Report 6 December

1162. Since 19 November, 65 pregnant women and 554 nursing mothers, have received the Comirnaty vaccine in Pavlodar, Kazakhstan (click here). Report 6 December.Vaccine in pregnancy news report

1161. An unnamed women in her early 30s, with Covid, died during a caesarean section at 32 weeks on December 18th, 2020, at an unnamed hospital in the Kent area (click here). Report 5 December.

1160. Five women with COVID-19 gave birth in September and October 2021, at the National University Hospital, Singapore (click here). In all of 2020, the same hospital cared for only eight pregnant women with COVID-19 at any stage of pregnancy. All delivered healthy babies. In the same report KK Women’s and Children’s Hospital cared for 91 pregnant women with Covid from May to October 2021. Report 6 December

5 December

1159. Sarah Heyl, from Sacramento, California, contracted Covid, and gave birth by Caesarean, four months ago, at 36 weeks (click here). She, and the baby, survived. She had not been vaccinated. Report 2 December

1158. Adrienne Chandler, from Milwaukee, Wisconsin, contracted Covid two weeks ago, and died shortly after giving birth to her fourth child (click here). She had not been vaccinated. Report 3 December

1157. Tori O’Rourke, 25, from Kinvara in Co Galway, was pregnant with twins when she contracted Covid at 24 weeks (click here). She gave birth in Malaga, Spain, 3 months ago. Both her and the twins survived. Report 5 December

1156. Tanviha, Christina and Joanne all contracted covid while pregnant (click here). They were all seriously ill, Tanviha required ECMO, but all survived. They all three required Caesarean and their babies also survived. None of them had been vaccinated. Report 4 December

30 November

1155. Jana Pittman, 39, doctor and Olympic athlete, got vaccinated while 18 weeks pregnant with twins (click here). Report 30 November Vaccine in pregnancy news report

1154. Jamieleigh Carne, from Middlesbrough, UK, contracted Covid at 14 weeks (click here). She recovered, and is now 32 weeks gestation. Report 29 November.

1153. 933 pregnant women have been vaccinated in Trinidad & Tobago (click here). Report 29 November Vaccine in pregnancy news report

1152. 282 pregnant women had contracted Covid in Trinidad & Tobago, by August 9th, and one had died. (click here). See also NR 1030. Report 9 August.

1151. Erica DeCelle, from Salem, Massachusetts, has mild Covid and her baby is due in Feb 2022 (click here). She had been vaccinated, and is recovering. Her husband and daughter had not been vaccinated and are both currently severely ill, and being ventilated. Report 29 November

1150. At least 781 pregnant women vaccinated in Nagpur, India (click here). Report 30 November Vaccine in pregnancy news report

1149. The wife of Naph Jabon, contracted Covid and gave birth by C-section at Long Island Jewish Medical Center in New York in early 2020 (click here). Report 29 November.

1148. Melia Nugraha, from Indonesia, contracted COVID-19 near term (click here). Report 30 November

29 November

1147. Nida Pelit from Kocaeli in northwestern Turkey contracted Covid at 31 weeks (click here). She was delivered by caesarean, required treatment with ECMO, and 40 days in ICU. Mother and baby recovered. Report 29 November.

26 November

1146. Anniree Muir, 23, contracted Covid at 29 weeks gestation on September 18 (click here). She required delivery by Caesarean at Bradford Royal Infirmary, and was seriously ill. She and the baby recovered. She had not been vaccinated. Report 26 November.

23 November

1145. Amy Yamaguchi, 22, from Orange County, California, contracted Covid at term and gave birth by Caesarean in October 2020 (click here). She then spent 5 months on ECMO at Cedars Sinai before undergoing a lung transplant. After many complications she recovered. Report 18 November. Update 1 Feb 2022 (click here). In this later report the baby’s birth date is given as 7 December 2020. AY started ECMO 13 December. Lung transplant 10 April 2021. Report 1 Feb 2022

1144. Sophie Byrne, 28, contracted covid and was delivered by Caesarean at 29 weeks (click here). She spent 11 weeks in hospital incuding a prolonged period ventilated but recovered. The baby survived. She had not been vaccinated. Report 23 November

18 November

1143. On November 2nd 2021 at the “Clinic for Infectiology Dr. Fran Mihaljevic” in Zagreb, one of two pregnant women on ECMO died. There are also two pregnant women “in a very bad state” at KBC hospital in Split, Croatia (click here). Report 2 November

1142. Katie Berry from Almondbury near Huddersfield, caught Covid-19, and gave birth at Calderdale Royal Hospital on August 22nd, at 27 weeks (click here). Ms Berry was in an induced coma for six days. Mother and baby recovered. Report 17 November

17 November

1141. Stephanie Curran, 28, from East Kilbride contracted Covid at 26 and gave birth immediately on October 15 (click here). She spent 24 hours intensive care unit at Glasgow’s Queen Elizabeth Hospital and recovered. The baby remains in NICU. Report 16 November

1140. Antonietta Delli Santi, age 26, contracted COVID-19 at about six months gestation, at the end of August. Her baby was delivered prematurely and died a few days later. Anotonieta died on 14 November, at a hospital in Naples (click here). She had not been vaccinated. Report 16 November.

16 November (HT Drs Christoph Brezinka & Branka Firulovic for news reports 1126 to 1139)

1139. An unnamed 28-year old woman died from Covid at 8 months of pregnancy in Plovdiv, Bulgaria (click here). Report 1 October

1138. On October 18.2021 an unnamed 28-year-old died at Sliven hospital, Bulgaria, from Covid (click here). She was at 22 weeks of gestation with twins. On the same day she had a cesarean, both babies died. The patient had presented with symptoms but had refused admission and was brought in a deteriorating condition later. Report 18 October.

1137. On October 16. 2021 an unnamed 20-year-old in the sixth month of pregnany died at Statu Mare hospital, Romania, from Covid after being delivered by cesarean (click here). The baby died too. She had been admitted with symptoms six days before. Riot police were called to defend hospital staff from 50 members of the patient’s family who threatened staff. Report 16 October.

1136. On October 11. 2021 an unnamed 32-year-old mother of three from Drobeta Turnu Severin died at 32 weeks of pregnancy in Bucur hospital, Bucarest, Romania (click here). She had not been vaccinated. Report 12 October

1135. On October 8. 2021 a young pregnant woman who had been admitted to Ploiesti hospital, Romania, in a serious condition died (click here). No further details. Report 8 October

1134. On October 5.2021 a 32 year old pregnant woman from Nucean, Romania, died in Oradea hospital in the 7th month of pregnancy from Covid (click here). She had not been vaccinated and had self-medicated at home with paracetamol for 11 days. Report 6 October.   

1133. On September 26 2021 a 34-year old woman in the 8th month of pregnancy, a nurse from Baia Mare hospital, Romania, died from Covid 3 days after her baby daughter who had been delivered by cesarean (click here). She had not been vaccinated. Report 26 September.

1132. On September 17.2021, 20-year old  Paula Ros from Nasaud, Romania, died from Covid at Bistrita hospital after a cesarean at 30 weeks (click here). The baby was transported to a specialized clinic in Cluj-Napoca where he is being ventilated. She had refused vaccination and had been infected by an aunt. Report 18 September

1131. On 31.07.2021, a Covid-19 positive pregnant patient at 28 weeks died in an ambulance transporting her from Arad to Timisioara, Romania.  The manager of  Timisioara hospital (Raul Patrascu) declared that his hospital had not been informed of the transfer, that saturation was already very low and intubation was performed too late. A different 33 year old woman at 25 weeks of gestation died of Covid. She had been transferred from Tirgu Mures hospital to Alba Julia hospital,Romania, because of her deteriorating condition: serious bilateral broncho-pneumonia, hepatic and respiratory failure. On August 30.2021 a 36-year old pregnant patient died from Covid at Piatra Neamt hospital. She lived in Spain and was visiting relatives. On arrival at the airport she had a negative test. She was admitted to hospital on August 12th, intubated and delivered of a premature baby one week later by cesarean. She was transferred to Spitalul Sfântul Spiridon hospital in Iasi, Romania, where she died two weeks later (click here). Report 18 September

1130. A Serbian tabloid lists eight women who died from Covid related to pregnancy (all not vaccinated) since the beginning of vaccination in Serbia (dates given as day-month-year). Four not reported elsewhere as follows. On 7.4.2021, D.T. (29 yrs ) died in“Dragisa Misovic“ hospital, Belgrade. On 19.04.2021, I.M.(32) a mother of five from Kostolac died at 4 months of gestation in Pozarevac hospital. On 29.04.2021, M.P. (27) from Zajecar, died at Nis hospital after being delivered of a healthy girl. On 19.08.2021, Milijana Radanovic (31) from Vlasotince, died in 6th month of pregnancy at Krusevac hospital. The other four are the same as NR 1126-1129 below. Report

1129. On October 10th, 2021, 33 year old S.I. from Arandjelovac died from Covid-related complications at Dragisa Misovic, Belgrade, Serbia, shortly after being delivered of a healthy boy by cesarean (click here). Report 12 October

1128. On October 2nd 2021, 20 year old Jovana Petrovic from Knjazevac, Serbia, pregnant with twins in the 4th month of gestation was admitted to Nis hospital in a serious condition with O2 partial pressure of 80% (click here). She died the following day. She had not been vaccinated. Report 6 October

1127. A 23 year old woman Anja J from Pirot, Serbia, died of Covid complications at Nis on Sept 24 2021 after being delivered of a 3400g baby girl  by cesarean (click here). She had not been vaccinated. Report 24 September

1126. A 33-year old Ana Pecić Jerotijević from Vrnjacka Banja, Serbia, died on October 8th 2021 Kragujevac hospital from Covid-related complications. She had been deliverd at 8 months of gestation by emergency cesarean, the child was intubated and transferred to NICU (click here). Report 9 October

13 November

1125. Lynlee Nichols contracted covid and gave birth by Caesarean on 8 August (click here). She required prolonged ventilation and later ECMO at Brookwood Medical Center, in Birmingham, Alabama, and was considered for a lung transplant but eventually recovered. The baby was fine. Report 12 November

12 November

1124. Danielle Williams, Melanie Hunter and Alice McIntyre all conceived shortly after getting vaccinated (click here). The first two have now given birth. Alice McIntyre’s pregnancy is ongoing. Report 8 November

1123, Alison Cornthwaite and Erica Hurteau got vaccinated while pregnant (click here). Report 12 November. Vaccine in pregnancy news report.

1122. Jessica McCullough contracted COVID-19 in her third trimester and gave birth at 34 by C-section at Memorial Health in Savannah (click here). She spent 39 days in hospital but survived. Her child survived. Report 11 November

10 November

1121. Rohaetin, the wife of Yulian Teguh Setiawan, and a health worker at the Gunung Jati Regional General Hospital in Cirebon, West Java, contracted Covid in late pregnancy and died (click here). Her baby survived. Report 10 November.

1120. Paola Gambini, 32, of Groveland, Florida, contracted severe Covid in late July at 33 weeks (click here). She gave birth on July 30 and was transferred to Orlando Health Regional Medical Center, where she was on ECMO for more than 40 days. She recovered. She had not been vaccinated. The baby survived. Report 9 November.

1119. Teresa Cadena, a nurse in Texas, got vaccinated post natally and continued breast feeding (click here). Report 10 November. Vaccine in pregnancy news report

9 November 2021

1118. Katie Leeming, 22, contracted covid and gave birth by Caesarean on 13 October at 26 weeks at Royal Preston Hospital (click here). She recovered, but her baby tested positive and died at 9 days. Ms Leeming had not been vaccinated. Report 9 November.

7 November 2021

1117. As of 2 November, 1,448 pregnant women have tested postive in the Dominican Republic (click here). Report 3 November

1116. Seventeen pregnant women have died from Covid in the country of Georgia from the start of the pandemic to 1 October (click here). One in 2020 and 16 in 2021. None of them had been vaccinated. Over the same period 7,338 pregnant women contracted the virus. Report 5 November

1115. Bailey Harvey got vaccinated at 19 weeks (click here). She is due in a few weeks. Report 6 November. Vaccine in pregnancy news report

1114. An unnamed 38-year-ol pregnant woman died from Covid in Thessalonika, Greece, in September after giving birth by Caesarean (click here). Another is currently on a ventilator. Report 1 November

1113. Paula Gambine from Orlando contracted Covid on 29 July and gave birth by Caesarean on 30 July (click here). Her condition deteriorated and she spent 85 days in Orlando Health’s Regional Medical Center, on a ventilator and ECMO. She and the baby recovered. Report 7 November.

1112. Saiqa Parveen, 37, from Birmingham, UK, contracted Covid at 8 months gestation in mid September and was delivered by caesarean on September 26 (click here). She died early in November. She had not been vaccinated. Report 7 November

6 November 2021

1111. Jessica Papali’i-Curtin, a trainee plastic surgeon, was vaccinated in the third trimester and gave birth to a healthy baby in late September (click here). Report 3 November. Vaccine in pregnancy news report

1110. Talashea Foster, from Lancaster, South Carolina, tested positive at 35 weeks and gave birth by C-section on July 30 to a healthy baby (click here). She was severely ill, spent over two months on a ventilator, but recovered. Report 1 November.

1109. Monic Ritz, contracted covid on 4 November, 2020 at 34 weeks (click here). She also had pre-eclampsia. Both mother and baby recovered. Report 5 November.

1108. Saskia Lane, 21, contracted Covid in August at eight months gestation, gave birth by caesarean and spent three weeks ventilated at the Princess Royal Hospital in Haywards Heath (click here). She had not been vaccinated. She and the baby survived. Report 4 November.

4 November 2021 – NR 712 updated with link to vaccine source 73 (click here).

31 October 2021

1107. Megan Denk, 30, contracted COVID-19 at the beginning of September, at 24 weeks gestation (click here). She received a monoclonal antibody treatment at UPMC Magee-Womens Hospital, recovered and the pregnancy is ongoing. She had had the Pfizer vaccine in January. Report 29 October

1106. Krystal St. Pierre contracted covid while pregnant, was ventilated, and gave birth by Caesarean at about 28 weeks at Royal Columbian Hospital in New Westminster, British Columbia (click here). She remains on ECMO. She had not been vaccinated. The baby is recovering. Report 27 October

1105. Stacey Martin, from New Bern, North Carolina, contracted Covid late in her pregnancy and died shortly after giving birth (click here). Her baby survived. Report 29 October

1104. Andrea Contreras, from Halifax, Canada, contracted Covid while pregnant and gave birth normally (click here). She and the baby recovered, but her husband, who also had Covid, later died from the disease. Report 30 October

28 October 2021

1103. An unnamed 23-year-old woman from Lithuania died from Covid shortly after giving birth by Caesarean (click here). She had given birth in another hospital in Kaunas and on 21 October was transferred to the Intensive Care Clinic at the Kauno Klinikos hospital of Lithuanian University of Health Sciences, where she died on 27 October. She had not been vaccinated. She is reported to be the first maternal death from Covid in the country. Report 28 October.

1103. Sultana Ashiq, from Dunstable, contracted Covid while pregnant with twins and gave birth at 32 weeks (click here). She was seriously ill requiring a prolonged period in ICU and a tracheostomy but recovered. The twins also recovered. Report 28 october

26 October 2021

1102. Twenty three pregnant women are being treated for Covid in Atyrau, Kazakhstan (click here). Eleven as inpatients. Report 25 October

1101. Judith from Melboure, Australia gave birth normally to her first child and on her husband’s advice decided to delay vaccination till she stops breasfeeding at one year (click here). Report 26 October. Vaccine in pregnancy news report

1100. Hajah Najibah binti Haji Usin tested positive when she gave birth at the National Isolation Centre (NIC), Borneo on September 30 by Caesarean (click here). She remained asymptomatic and her baby tested negative. She had been vaccinated. Report 26 October.

1099. Kalley Newkirk, 25, from the Mayo Clinic, got one shot of the Pfzier vaccine in January. Soon after she developed a mood disorder and soon after that suffered two miscarriages a month apart. She is currently pregnant again, and has declined the second dose (click here). Report 25 October. Vaccine in pregnancy news report

24 October 2021

1098. Nea Gates got her first vaccine dose on Oct. 6, at seven months gestation (click here). Report 18 October. Vaccine in pregnancy news report

1097. Cheryl Franko, from Edmonton, Canada, got vaccinated while pregnant, first dose in March 2021, second in June, but contracted covid on August 23rd and gave birth on the 27th at term (click here). The covid was mild and her baby tested negative. Report 18 October. Vaccine in pregnancy news report

1096. Amanda Harrison, 36, from Phenix City, Alabama, contracted covid at 29 weeks (click here). She was intubated and flown to a hospital in Birmingham, where she gave birth at 32 weeks. She and the baby recovered. She had not been vaccinated. Report 19 October.

1095. An unnamed pregnant woman recently died from Covid in Hawaii (click here). Her baby survived. She is the third to die since September. Report 21 October

1094. Taylor Manning, 31, contracted covid at 35 weeks and gave birth by Caesarean on 3rd August at Ocean Springs Hospital, Mississippi (click here). She required prolonged ventilation and a tracheostomy, but recovered. She had not been vaccinated. Report 22 October

1093. Kristin Lammert contracted Covid at 10 weeks gestion, recovered, and gave birth normally on August 25th (click here). Report 24 October

1092. Wendy Davidson from Coweta County, Georgia, contracted Covid and required ventilation. After two weeks she gave birth at 28 weeks by Caesarean at Kennestone Hospital (click here). She recovered. She had been vaccinated. Report 22 October.

1091. Louise Read, 35, contracted covid at 38 weeks, at the end of August, and gave birth by Caesarean at St Richard’s Hospital in Chichester (click here). She spent a week in ICU but recovered. She had not been vaccinated. Report 20 October.

1090. Amanda Perry, 36, from Dickson County, Tennessee contracted Covid and gave birth by Caesarean at 32 weeks on September 15 (click here). She was airlifted, to Virginia, for intensive care, but died on October 18th. She had not been vaccinated. Report 23 October

1089. Maria Roque-Diaz caught the coronavirus in November 2020, and gave birth a month later, at 32 weeks by Caesarean, while ventilated and on ECMO, at the University of Maryland Medical Center(click here). Both mother and baby recovered. Report 23 October

16 October 2021

1088. Brittany Cavanagh, from New Zealand, got her first vaccine dose in August, second in September, and is due at the end of October (click here). Report 15 October Vaccine in pregnancy news report

1087. Chloe Geoghegan and Annadina de Santis both got vaccinated while pregnant and had healthy babies (click here). Report 16 October. Vaccine in pregnancy news report

15 October 2021

1086. Kim Smith, 34, from Mitchell, South Dakota, contracted severe COVID-19, and gave birth on August 23rd, at 32 weeks, at Avera Hospital in Sioux Falls (click here). Her health deteriorated after the birth and she required ventilation for over a month. She remains in hospital. She had not been vaccinated. The baby recovered. Report 14 October Update 29 December (click here).

1085. Arianne Peters, from Corbin, Kentucky, contracted Covid in May and gave birth at the University of Kentucky Medical Center at 29 weeks (click here). Her baby suffered many complications, spent 75 days in the NICU, but recovered. Report 15 October

13 October 2021

1084. Valerie Gotie, a nurse practitioner at the Wilmot Cancer Institute at the University of Rochester Medical Center, got vaccinated in December 2020, while pregnant (click here). Her baby is fine. Report 11 October. Vaccine in pregnancy news report

1083. Jenny Lappin, a 35-year-old marketing manager in Reading, Haya, a 33-year-old company director in London, Polly Gooch, a 27-year-old business analyst in Norwich, and Catriona, 35, who works in aviation in Aberdeenshire, got vaccinated while pregnant (click here). Report. 12 October. Vaccine in pregnancy news report

1082. Ashley Bridgwaters (click here). No further details.

1081. Wendy Leal, from San Antonio, Texas, contracted Covid and gave birth to twins by Caesarean on 11th, or possibly 8th, October (click here). She had not been vaccinated. The twins are alive. Report 12 October

1080. Gabriela Acuna, 29, contracted Covid and had an emergency C-section on September 13 at 26 weeks gestation (click here). She is currently seriously ill on a ventilator and is reported to be hoping for a lung transplant. She had not been vaccinated. Her baby is alive. Report 12 October

1079. Claire Bromley, 33, from Kent, contracted severe Covid and required two weeks on a ventilator (click here). She recovered and the pregnancy is continuing. She had not been vaccinated. In the same report Kelsie Routs, 23, gave birth prematurely by emergency C-section and was placed in a medically induced coma for some days. She and her baby recovered. She had not been vaccinated. Report 11 October

7 October 2021

1078. Rosebluff Thomas Jennifer, 36, from Edmonton, Canada, contracted Covid, gave birth by Caesarean but died of Covid shortly after, on 3 September (click here). She had not been vaccinated. See NR 1025. Possibly the same woman. Report 6 October

1077. East Enders actress, Louise Lytton, 32, gave birth by Caesarean in September and contracted Covid shortly afterwards (click here). She recovered. Report 7 October

1076. A paternal postnatal death from Covid. Shilan Wali, the wife of Sirwan Ali from Kirkuk, Iran, gave birth to twins on 9 July (click here). She and the twins were fine, but Sirwan contracted Covid on 1 September and died on 1 October. Report 7 October

6 October 2021

1075. Shantal Feliciano, from Port Orange, Florida, contracted severe covid and gave birth by C-section at Adventhealth, on Aug. 8 (click here). She remains on ECMO. She had not been vaccinated. Report 5 October

1074. Brittany Luvender, from Ohio, contracted severe covid and was delivered by Caesarean at 28 weeks on September 17 (click here). She died on 1 Ocotober. She had not been vaccinated. The baby is fine. Report 5 October

1073. Kelsie Routs contracted Covid at 28 and was delivered by Caesarea (click here). She spent a week on a ventilator but recovered as did the baby. She had not been vaccinated. Report 5 October.

4 October 2021

1072. Emily Robison, 22, contracted Covid and gave birth by Caesar, at 28 weeks, at Mercy Hospital Fort Smith (click here). She spent a month on ITU and died on 20 September. She was unvaccinated. The baby is recovering in hospital. Report 4 October

1071. Autumn Carver, 34, from Indianapolis, contracted severe Covid and gave birth at Indiana University Health Methodist Hospital, by Caesarean, at 32 weeks (click here and here). On 18 September she had been on ECMO for over a month, and is awaiting a lung transplant. She had not been vaccinated. Report 1 October

1070. Marrisha “ReRe” Kindred Jenkins, 27, from Dekalb County, Georgia, contracted COVID-19 on September 4, gave birth at 33 weeks shortly after, and died on 23 September (click here) Her baby is healthy. She had not been vaccinated. Report 29 September.

1069. Carrie Summerset contracted covid in early August (click here). She gave birth at 29 weeks, and was intubated in ICU for over a month. She and the baby recovered. . Report 27 September

1068. Vicky Goodson, 40, from North Carolina contracted severe covid and gave birth on Sept. 11 by C-section, while ventilated (click here). She remains ventilated. She had not been vaccinated. The baby spent two weeks in the NICU but is now home. Report 3 October. Update 7 October. She died on 5 October (click here). Update report 6 October

30 September 2021

1067. Four women with Covid gave birth at the National Isolation Centre (NIC) in Brunei on 29/30 September (click here). They bring the total of Covid positive births in the NIC to 12. All 12 babies were delivered safely. Report 30 September

1066. An unnamed woman has died from Covid in Idaho (click here). The doctor reporting her death works at both St. Luke’s Magic Valley Medical Crenter in Twin Falls, Idaho, and at St Luke’s Medical Center in Boise, Idaho, so this may be the same case as the unnamed woman who was on a ventilator in NR 1015. Report 30 September

1065. Chequile Pettaway, from Houston, Texas, contracted Covid at term and gave birth on 2 August (click here). After the birth she required three weeks ventilation in ICU but recovered. She baby was fine. She had not been vaccinated. Report 29 September

1064. Deysi Moraes, from Boca Raton, Florida, contracted severe covid at 7 months gestation and gave birth by Caesarean at 32 weeks in July at Bethesda Hospital East (click here). The baby has been discharged but she remains on a ventilator, and her family understand that, because of brain and lung damage, she is unlikely to survive. She had not been vaccinated. Report 29 September

1063. An unnamed woman in Armagh, Northern Ireland, tested positive for Covid and later miscarried (click here). Report 29 September

1062. Lynn Carpenter, 21, contracted severe Covid at 7 months gestation and required ventilation for three weeks. She gave birth at 30 weeks on 8 Sept at Crouse Hospital in Syracuse, New York (click here). She is now off the ventilator but remains in ITU. Report 29 september

1061. Patience Buxton De Santiago, from Morton, Mississipi, contracted Covid and was delivered by Caesarean at 32 weeks (click here). She spent a month in ICU and remains on oxygen therapy, but her and the baby survived. In the same report Jessica Odom from Florida also had moderataly severe Covid and was delivered by C-section at 32 weeks. Both her and the baby recovered. Neither woman had been vaccinated. Report 30 September

1060. A pregnant woman with Covid was treated at Aberdeen Royal Infirmary (click here). Report 28 September

1059. Six unnamed pregnant women have died of Covid in pregnancy in Louisiana since mid-July (click here). They presumably included News Reports 927 and 1038. Report 28 September

1058. Six “parents of newborns”, preumably mothers although only one explicitly stated to be so, have Covid at the John Hunter Hospital Newcastle, Australia (click here). Report 30 September

1057. In the USA 161 pregnant women have died of Covid, with 22 deaths in the month of August 2021 (click here). Report 29 September. The source of these data is a CDC advisory (click here), also issued on 29 September.

27 September 2021

1056. An unnamed woman, aged 38, from Okinawa, Japan, contracted Covid, and gave birth on 28 August at 24 weeks at the University of Ryukyus Hospital (click here). The mother recovered. The baby remains in hospital. She had not been vaccinated. Report 27 September

1055. Carrie Somerset contracted covid in early August and gave birth at 29 weeks (click here). She required over a month of ventilation, but she and the baby recovered. Report 27 September

1054. Marrisha Jenkins, 27, from Atlanta, Georgia, contracted covid on 4 September at 36 weeks (click here). She gave birth on 7 September to a healthy baby. She was treated at home but died suddenly about two weeks after the birth. She had not been vaccinated. Report 27 September

1053. Alicia (Santana) Rogers, 30, from Colorado contracted covid about a week after giving birth to twins (click here). She died two weeks later on 7 September. She had not been vaccinated. Report 27 September

25 September 2021

1052. Jaidyn Dahn, 27, of Jackson, Michigan, contracted mild Covid at 18 weeks gestation (click here). She recovered and gave birth normally at Henry Ford Allegiance Health on 22 July. Report 24 September

1051. An unnamed pregnant woman with Covid from West Virginia tested positive for Covid and no hospital will accept her for drug abuse treatment until she tests negative (click here). Her pregnancy is ongoing. Report 24 September

1050. Two unnamed pregnant women in Hawaii have died of Covid during September (click here). Both babies survived. See also NR 1032. Report 20 September

1049. An unnamed woman, age 20, with severe covid, was delivered by caesarean at 28 weeks at Hadassah Medical Center, Jerusalem, on 24 September (click here). She is critically ill on life support. Another unnamed woman, aged 27, also with Covid was delivered by Caesarean at 27 weeks on the same day. She is being ventilated. Report 24 Sepember.

1048. Samantha Kelly, from McHenry, Illinois,contracted Covid at 32 weeks (click here). She was seriously ill, required delivery by Caesarean and ventilation, but her and the baby recovered. She had not been vaccinated. Report 22 September

1047. Dr. Kelly Ferroni, an obstetrician at University of Iowa Hospitals and Clinics (UIHC) contracted covid in October 2020 at 26 weeks (click here). She gave birth in Feb 2021 normally to a healthy baby. Report

1046. Abby Sgro from Springfield, Illinois, got vaccinated in the third trimester and had a healthy baby (click here). Report 21 September. Vaccine in pregnancy news report

1045. Ankara City Hospital, Turkey, has 25 pregnant women admitted with Covid, none of whom are vaccinated (click here). Fatma Aybar, 29, is one, and is recovering. In the same report Tülin Sargın, 34, got vaccinated during pregnancy, after she had tested positive. Report 20 September. Vaccine in pregnancy news report

1044. Patricia Denise Jackson, 31, contracted severe Covid and gave birth by Caesarean on 1 Sept at a hospital in Phoenix, Arizona (click here). She died on 13 Sept.  Report 25 September.

1044. Lorren Reeves, 26, contracted severe covid in July at 26 weeks, required ventilation, and gave birth by Caesarean at 27 weeks, at Derriford Hospital, Plymouth (click here). Her and the baby recovered. She had not been vaccinated. Report 19 September

1043. Prem Koonkhuntod from Myrtle Beach, South carolina, contracted Covid in early August at seven months (click here). She gave birth by Caesarean, and required ECMO, at the Medical University of South Carolina (MUSC), but recovered. The baby also survived. She had not been vaccinated. Report 25 September

1042. Bianca Carrington, 29, contracted Covid at 8 weeks and miscarried (click here). She died soon afterwards. She had not been vaccinated. In the same report five unnamed pregnant women died of Covid at the University of Mississippi Medical Center, over a four week period. It is not clear if she was one of them. See also NR 854 and 899. Report 23 September

1041. Cecilia Vega-Britez, 36, from Brewster, New York, contracted Covid at 26 weeks (click here). She recovered and the pregnancy is ongoing. She had not been vaccinated. Report 24 September

1040. Fationa Nikolli tested positive at 31 weeks and was delivered by Caesarean at Birmingham Women’s Hospital on 6 July (click here). Her baby was stillborn. Report 23 September

17 September 2021

1039. Samantha Kelly, from Crystal Lake county in Illinois, had severe Covid and gave birth at 33 weeks. (click here). She is currently on a ventilator. Report 16 September

1038. Keighlie Renee Reaux, 24, from Louisiana, contracted on July 26 at 38 weeks pregnant (click here). She gave birth to a healthy child by Caesarean on 4 August. She was ventilated on 9 August, suffered a cardiac arrest on 21 August and died on 12 September. She had not been vaccinated. Report 16 September

1037. Katie Moran, who worked at Unity Health in Searcy, Arkansas, contracted Covid early in August around the same time she gave birth (click here). On August she was transferred to a hospital in Memphis and intubated. She died on 15 September. Her baby’s outcome and her vaccination status were not reported. Report 16 September

1036. Vanessa Rickard, 36, a Filipino employment pass holder in Singapore, contracted Covid in August at 37 weeks (click here). She gave birth at 38 weeks at Singapore General Hospital, and was separated from her baby for 2 & 1/2 weeks. Both recovered. She had not been vaccinated. Report 16 September

15 September 2021

1035. Two unnamed women with Covid gave birth in Lapu-Lapu city hospital, the Philippines, on 14 September (click here). Report 15 September

1034. Lyn-Fatt Colquhoun, a mental health officer at the Black River Hospital in St Elizabeth, died from Covid on 10 September, at the University Hospital of the West Indies, three weeks after giving birth (click here). Report 14 September

1033. Esmeralda Ramos, 43, from Victorville, California, who was due in November, contracted Covid, lost the pregnancy, and is now on a ventilator (click here). She had not been vaccinated. Report 14 September

1032. An unnamed woman died from Covid in Hawaii shortly after giving birth (click here). The baby survived. Report 14 september

13 September 2021

1031. Valerie Allen, 29, from Statesville, North Carolina, contracted Covid on 3 August and gave birth normally at term, on 8 August (click here). Postnatally she became severely ill and require ITU treatment, but it is not clear if she was ventilated. She recovered. She had not been vaccinated. Her baby was fine. Report 12 September

1030. Police officer Anisa Khan, from Cunupia, Trinidad and Tobago, died of Covid on 11 September, one week after giving birth (click here). In the same report, one other unnamed pregnant woman had died of Covid, out of 383 who had contracted the virus in Trindad and Tobago up to 1 September. It was not known whether Khan had been vaccinated. Report 13 September

11 September 2021

1029. 36 pregnant women with Covid are currently hospitalised in the Zhambyl province of Kazakhstan (click here). Seven are in ICU. Since the start of the pandemic 1,005 pregnant women have been infected in the province. Report 10 September

1028. An unnamed, unvaccinated woman in her thirties, from Corpus Christi-Nueces County, Texas, suffered a fetal death at 22 gestational weeks (click here). She had Covid. This is the third such fetal death to women with Covid in the county. Report 10 September.

1027. ESPN college football and basketball reporter, Allison Williams, who is trying for a second child, has decided not to get vaccinated (click here). Report 10 September. Vaccine in pregnancy news report

1026. Haylie Kelly contracted mild Covid in August and has recovered (click here). She is due to give birth later in September. She has still not been vaccinated. In the same report five pregnant women have been admitted to West Penn Hospital, Pittsburg, in the past month with severe covid. Report 10 September

1025. An unnamed woman from Alberta has died from Covid in an Edmonton Hospital shortly after giving birth (click here). She had not been vaccinated. Her baby survived. Report 10 September

1024. 41 pregant women have died of Covid in Sri Lanka since the start of the third wave (click here). About 5,500 pregnant women have been infected. Report 10 September

1023. Madelyn Zwick-Watson, 19, from Ludlow, Cincinnati, contracted Covid in late August and gave birth by caesarean at 33 weeks on 5 September (click here). She is now being ventilated at University of Cincinnati Medical Center, and the doctors are considering using ECMO. She had received the first dose of vaccine in late August. Her baby is doing fine. Report 10 September

1022. Davy Mathias, (in some reports Macias), 37, a labour and delivery nurse, from Yucaipa, California, gave birth on 18 August and died of Covid on 30 August (click here). She had not been vaccinated. The baby is healthy. Report 31 August

1021. Ten pregnant women have died of Covid in Princess Margaret Hospital, Nassau, the Bahamas, since the pandemic began (click here). Three died in the past six weeks. Over the whole pandemic the hospital has treat 130 pregnant women with Covid. Report 10 September

1020. Erin Hogg 20, from Wisbech, was vaccinated while pregnant, although she didn’t know she was pregnant at the time (click here). She gave birth normally on 10 August at The Queen Elizabeth Hospital King’s Lynn. Report 10 September Vaccine in pregnancy news report

10 September 2021

1019. Myra Bantigue-Obolsky, 35, from Jacksonville, Florida, contracted Covid at 31 weeks, was delivered by Caesarean and died 12 days later (click here). She had not been vaccinated. Her baby survived. Report 9 september

1018. An unnamed woman, who is 24 weeks pregnant, is in the intensive care unit at John Hunter Hospital, Newcastle, Australia (click here). She had not been vaccinated. In the same report, Caroline McCarthy got the first foes of the Pfizer vaccien while pregnabnt. Report 31 August

1017. In August an unnamed woman, from Sydney, Australia, with severe covid was delivered by Caesarean at 28 weeks and placed on a ventilator (click here). Report 10 September

9 September 2021

1016. In February 2021, an unnamed Tokyo woman in her 30s, who was 37 weeks pregnant contracted Covid (click here). After two weeks in a Tokyo hospital she gave birth naturally at 39 weeks. Mother and baby were fine. Report 6 September

1015. Ashlee George got vaccinated early in her pregnancy (click here). She is due 1 January 2022. In the same report an unnamed pregnant woman with COVID-19 was being ventilated in the ICU at St. Luke’s Medical Center, Boise, Idaho, on 1 September. Report 5 September. Vaccine in pregnancy news report

1014. Madeline Woods from Sydney Australia tested positive two days after giving birth at Campbelltown Hospital (click here). Her baby also tested positive age 8 days. Both recovered. Report 6 September.

1013. Nancy Notzon from Newcastle, Australia, got vaccinated in August at about 6 months gestation (click here). Report 7 September

1012. Sharnai Crossland, 23, from Dukinfield, Greater Manchester, tested positive for Covid on July 18, and was nursed at home (click here). However some days later her baby died in utero and she gave birth on July 28. She had not been vaccinated. Report 6 September

1011. According to Facebook and Twitter, FoxNews reported that Krystal Blackwell, from Seagoville, Texas, died from Covid three days after giving birth (click here or here). However the main Fox News link https://www.fox4news.com/news/seagoville-mom-of-three-dies-from-covid-19-days-after-giving-birth has been taken down. Reports 8 September

1010. Jasmine Ballard from St Louis County, Missouri, contracted Covid and required delivery by Caesarean at 26 weeks on 4 August (click here). She required ventilation, and ECMO was attempted, but was unsucessful. Despite this she is now off the ventilator and her and the baby are recovering in hospital. She had not been vaccinated. Report 5 September

1009. An unnamed 30-year-old unvaccinated woman with Covid gave birth at the Emek Medical Center in Afula, Israel (click here). She was transferred to the ITU at Carmel Medical Center in Haifabut where she died on 7 September. Another unnamed 28-year-old unvaccinated woman, who had recently given birth via C-Section is currently ventilated at Hillel Yaffe Medical Center in Hadera. In the same report 25 pregnant, and 26 post partum, women are currently hospitalized due to COVID in Israel. Report 9 September.

1008. Sara Caitlin Vilchez, 31, of Elgin, South Carolina, contracted Covid early in August and gave birth on Aug. 15 (click here). Three days later she required ventilation, and later died of surgical complications. She had not been vaccinated. Report 9 September

1007. Felicia Cabrera-Saez, from North Carolina, contracted Covid at about 20 weeks gestation (click here). She required prologed ventiation and a period of ECMO but was discharged from hopital with the pregnancy ongoing on May 28. She gave birth to a healthy baby in July. She had not been vaccinated but has now received her first dose. Report 8 September. Vaccine in pregnancy news report

1006. Two unnamed pregnant women with Covid were ventilated and delivered preterm recently, at OSF Saint Francis Medical Center, Peoria, Illinois (click here). In the same report Yohane Matuce got the first shot of the Pfizer vaccine at St. Mary’s Medical Center, Palm Beach, Florida, on Aug. 31. Report 9 September. Vaccine in pregnancy news report

1005. An unnamed 27-year-old woman with Covid gave birth to triplets at the De Soyza Maternity Hospital in Colombo (click here). The mother and the three children were said to be in good health. Report 9 September.

1004. An unnamed 29-year-old woman (known only as Case 777) died of coronavirus complications, two weeks after giving birth via Caesarean section on August 24, at the National Isolation Centre (NIC) in Brunei (click here). In the same report eight pregnant women who tested positive for COVID-19 were receiving treatment at the NIC. Four had given birth in the last month. Report 9 September. Update 11 September. She had also been treated with ECMO (click here).

4 September 2021

1003. An unnamed pregnant woman contracted Covid in May at (click here). She required ventilation at Virtua Voorhees Hospital, airlift to the Hospital of the University of Pennsylvania, and Cesarean birth at 30 weeks. After six weeks ventilation, she is undergoing rehabilitation. She had not been vaccinated. The baby survived. Report 4 September

1002. Brittany Campana, 29, a labor and delivery nurse at Sarasota Memorial Hospital, Florida, contracted severe covid during pregnancy (click here). She was delivered by Caesarean preterm, and both her and the baby recovered. She was not vaccinated. Sarasota Memorial Hospital had more than 50 pregnant women severely sick with COVID in August. Report 3 September.

1001. Two unnamed women with Covid gave birth recently to babies who also tested positive, at Hidajete Krasniqi hospital, Peja, Albania (click here). Both mothers and both babies recovered. Report 3 September

1000. Shakira Ramdihal from Leeds contracted covid at 20 weeks, and gave birth prematurely at 22 weeks at St James’s University Hospital on 28 July (click here). She recovered, but the baby died. Report 4 September

999. Shem McLeod, 43, contracted severe Covid and was delivered by Caeasarean on 25 July, at 33 weeks (click here). She survived after 5 weeks in coma, but remains in Walsall Manor Hospital, UK, undergoing rehabilitation. She had not been vaccinated. Her baby survived. Report 3 September

998. The wife, age 31, of Junior Laurent contracted severe Covid and was delivered by Caesarean at 32 weeks at Jackson Memorial Hospital, Florida (click here). She had not been vaccinated. Both mother and baby recovered. Report 3 September

997. Kyndal Nipper, from Georgia, contracted mild Covid at 36 weeks gestation (click here). She recovered but her baby was stillborn. She had not been vaccinated. Report 3 September

996. Dr Pratiksha Gavali, a pathologist at Irwin Hospital in Amravati, Maharashtra, tested positive for covid-19 in October 2020. Later, she delivered a stillborn baby and died from the infection five days later (click here). In the same report Sunita Chaurasia from Mumbai contracted covid-19 late in pregnancy in March 2021. She survived but her baby was stillborn. Report 3 September 2021.

995. Angeline Eschette, 33, from Lockport, Louisiana, contracted mild covid late in her pregnancy (click here). She gave birth to a healthy baby on 30 August. She had not been vaccinated. Report 3 September

3 September 2021

994. An unnamed woman with Covid gave birth at Sultan Ismail Hospital in Johor Bahru, Malaysia (click here). Report 2 September

993. Kimmie Pavone died of COVID-19 on 1 September (click here). Two weeks earlier, at 30 weeks, she had been delivered by casearean, at Spring Valley Hospital, Las Vegas. She was unvaccinated. Her baby had “an underdeveloped lung and bleeding of the brain” and remains in intensive care. Report 3 September

992. Charlotte Alter got two doses of the Pfizer vaccine in May, the first at 12 weeks gestation (click here). Her pregnancy is ongoing. Report 1 September

991. Kristen Roy, 38, from Franklin, Indiana, contracted Covid on 9 July. She required ventilation, but her condition deteriorated and she was delivered by Caesarean on August 13 at 25 weeks (click here). Two weeks later she died at Indiana University Health Methodist Hospital, Indianapolis. She had not been vaccinated. Her baby is alive at Riley Hospital for Children. Report 2 September

990. One unnamed pregnant woman is in the critical care unit at East Suffolk and North Essex NHS Trust, UK. She has had only one dose of vaccine (click here). Report 2 September

2 September 2021

989. Amber Greenway, from St Augustine, Florida, died of Covid on 30 August (click here). She had given birth earlier in the month. Report 31 August.

988. Hajrah Aslam, 28, from Peterborough, contracted Covid in January 2021, at 35 weeks gestation (click here). She was placed into an induced coma for six weeks, followed by 11 weeks hospital rehabilitation, but her and the baby survived. Report 19 August

987. Morghan Elmore, 30, died of Covid in Silverdale Detention Center, a prison in Chattanooga, Hamilton County, Tennessee, shortly after giving birth (click here). She was not vaccinated. The child is “in bad shape”. Report 1 September

986. An unnamed woman, age 28, pregnant with triplets, contracted covid and recovered. Shortly thereafter she gave birth at the Puttalam hospital, Sri Lanka, on 1 September (click here). The babies were healthy. Report 2 September

985. Sabrina Dhillon, from Winnipeg, contracted Covid at 28 weeks and gave birth by Caesarean (click here). Both recovered but the baby required four months in ICU. Report 29 August

984. Davy Macias, 37, a nurse, from Yucaipa, California, died from Covid, on 26 August, at seven months gestation, shortly after giving birth (click here). She had not been vaccinated. Report 31 August

29 August 2021NR 940 updated. Reports 967 to 981 HT Branka Firulovic and Christoph Brezinka

983. Nadya Mustika Rahayu, the partner of Sworddut Rizki ‘DA’, a Malaysan celebrity, contracted Covid during her pregnancy, recovered, and gave birth to a healthy child on 13 April (click here). Report 18 April

982. Minal Waghmere, 32, died of Covid at 32 weeks on April 8 in the Kingsway Hospital in Nagpur, India (click here). Pryali Sur, the author of the report, contracted Covid in February while pregnant but recovered. Report 18 May

981. From the beginning of the pandemic until April 4th 2021 four pregnant patients had died from Covid at Pristina hospital, Kosovo (click here). Report 4 April

980. Duja Milanović Đurić, 28, died in the 7th month of pregnancy after being delivered by c-section on April 28 2021 in Bosnia (Republika Srpska) (click here). Report 28 April

979. An unnamed 22-year-old in week 30, died on May 16 2021 in UKC Republika Srpska hospital in Banja Luka, Bosnia (Republika Srpska). She had been transferred from Doboj hospital two weeks before with a positive Covid test and symptoms and delivered by c-section on May 3rd 2021 (click here). Report 17 May

978. Enida Goro, 38, from Fojinca, Bosnia, died from Covid on April 13. 2021. She was pregnant with her third child (click here). Report

977. An unnamed 38-year-old died from Covid on April 19 2021 at Podgorica hospital, Montenegro (click here). She had been delivered of a female newborn by cesarean five days before. The baby was breathing spontaneously. Report 19 April

976. An unnamed 29-year-old woman died from Covid 19, five days after cesarean on April 7th 2021 in Dragisa Misovic hospital, Belgrade, Serbia (click here). Report 7 April

975. An unnamed 32-year-old pregnant patient in 4th month of pregnancy died on April 9 in Pozarevac hospital, Serbia (click here). She was Covid-positive, and the cause of death was given as gastric ulcer perforation. Report 10 April

974. An unnamed 27-year-old died a day after giving birth on April 29 2021 in Nis hospital, Serbia (click here). She had been transferred from Zajecar hospital 3 days before, a cesarean was planned at 35 weeks but the anaesthesiologist delivered the baby vaginally. Possible duplicate report of the second case in NR 973.

973. Two unnamed pregnant women were reported to have died from from Covid related complications, despite a negative covid test, in Nis hospital, Serbia (click here). The first woman had been delivered by c-section on 26 July 2021 of a 900g baby who was transferred to NICU. The second woman was aged 27, but no further details were given. Report 29 July

972. An unnamed 31-year-old woman was transferred from Leskovac hospital to Krusevac hospital in Serbia, on August 2nd and died there from Covid-related complications on August 20 2021 at seven months gestation (click here). Report 22 August

971. An unnamed 32-year-old woman died from Covid pneumonia shortly after cesarean section in Croatia. The newborns weight was given at 2200 g (click here). Date of death was not given. Report 4 May

970. On June 17 2021, an unnamed 28-year-old pregnant woman died from Covid in Bulgaria (click here). Report 18 June

969. On April 30 2021 an unnamed 36-year-old pregnant woman died from Covid in Bulgaria (click here) Report 30 April

968. On April 24 2021 an unnamed 32-year-old pregnant woman died from Covid in Bulgaria (click here) Report 24 April

967. An unnamed 28-year-old woman died of Covid on April 1st 2021 in Sliven hospital “Dr. Vasilev Petrov“ in Bulgaria, two days after giving birth at 32 weeks (click here). The newborn survived and is Covid negative. In the same report an unnamed 36 year-old, 6 months pregnant, died on March 28 2021 in Umbal-Burgas hospital. She had been delivered by c-section on 19 March. On March 24th another unnamed patient, pregnant with twins, died after c-section. The father of the twins also died from Covid complications. Both infants were transferred to NICU and were Covid negative. Report 12 April

28 August 2021

966. An unnamed pregnant woman who tested positive for COVID-19 gave birth on 26 August at the National Isolation Centre, in Tutong, Bruei (click here). She was the second active case to give birth there. Report 27 August

965. Sierra Lacey from Oaklahoma got vaccinated during pregnancy and gave birth to a healthy baby (click here). In the same report an unnamed woman and her unborn baby died from Covid at Oklahoma University Medical Center at 31 weeks. Another unnamed pregnant woman with Covid required ECMO at Baptist Medical Center. Report 27 August. Vaccine in pregnancy news report

964. Victoria Kelehear, 26, from Florence, South Carolina, contracted Covid at 36 weeks and gave birth by caesarean in July (click here). Her baby is fine but Victoria required treatment with ECMO and currently remains on a ventilator at a Charleston hospital. Report 28 August Update 9 September (click here). She went home on 6 September.

963. Student nurse Keisha Chadwick, 28, from Ashton-under-Lyne, contracted Covid late in pregnancy (click here). She gave birth to a healthy baby but was diagnosed with breast cancer seven weeks later. Report 27 August

962. Two unnamed pregnant woman are being treated for Covid-19 at St Luke’s General Hospital, Carlow, Kilkenny (click here). Report 26 August

961. An unnamed woman with Covid gave birth to a stillborn baby, who also tested positive, on 22 August in France (click here). Report 23 August

960. Priyanka, 26, wife of Sreejith of Chengannur died from Covid at Thiruvalla Believers Hospital, in Kerala, India, shortly after giving birth by Caesarean at seven months (click here). The baby is in intensive care. Report 24 August

959. Filipino bossa nova singer Sitti, full name Sitti Katrina Baiddin Navarro-Ramirez, 36, got two doses of the Moderna vaccine during her pregnancy (click here). Report 23 August

958. An unnamed 34-year-old pregnant American woman died from Covid at the Cornwall Regional Hospital in St James, Jamaica, on 23 August (click here). Report 23 August.

957. Malaysian singer, Siti Sarah Raisuddin, 36, died from Covid three days after giving birth by Caesarean at eight months gestation at the Hospital Canselor Tuanku Muhriz (click here). Report 10 August

27 August 2021NR 940 updated. NR 956 added belatedly.

956. Dr Farha Niloufer, 31, a paediatrician from Gajwel district of Telangana, died due to COVID-19 a week after childbirth on 13 May (click here). She died at Princess Esra Hospital in the old city of Hyderabad. Report 13 May

955. Allison Hines from Bryan, Texas, contracted Covid at 36 weeks (click here). Her baby died at 37 weeks due to suspected placental thrombosis. She recovered. She had not been vaccinated. Report 24 August

954. By 7 August, 39 pregnant women had tested positive to COVID-19 in Sydney, Australia (click here). Report 23 August

953. Indian actress, Neha Dhupia, 41, contracted mild Covid early in pregnancy (click here). She recovered and the pregnancy is ongoing. Report 27 August

952. Edwina ‘Eddy’ Bartholomew, TV presenter of the Sunrise TV show in Australia, got vaccinated while pregnant (click here). Report 25 August.

951. Dr Samra Ali, a pregnant gynaecologist at the Wah International Hospital, Taxila, Pakistan, died of Covid-19 on 22 August (click here). Flight Lieutenant Dr Mahnoor Farzand, also pregnant, died from Covid at the Combined Military Hospital, Malir Cantonment, on the same day. Neither had been vaccinated. Report 24 August.

950. Madeline Sweezer, 24, from Centralia, Missouri, contracted Covid at 31 weeks on 22 July (click here). On 5 August she was delivered by Caesarean and placed on a ventilator. The baby survived but Madeline required two weeks in ITU. She recovered. She had not been vaccinated, although she has been now. Report 23 August.

949. According to this report 1.85% of pregnant women diagnosed with Covid in Thailand have died, and pregnancy related deaths accounted for 0.43% of deaths due to the disease between December and August 11th (click here). Report 25 August

948. Brontë Bates, 29, from South Shields, got two doses of the Pfizer vaccine while pregnant (click here). Report 25 August

947. Tricia Lee, from Wichita, who had previously had Covid, contracted it for a second time and required admission to hospital (click here). She recovered and the baby is due in about a week. Report 27 August

946. Lucy Smith, 18, contracted Covid, was delivered by Caesarean at James Cook University Hospital, Middlesbrough, UK, and required ventilation and four weeks in ITU (click here). She had not been vaccinated. Report 25 August. HT @Susan_Bewley.

945. Sixteen pregnant women with Covid have been treated in ITU in Belfast to date in 2021 (click here). Ten were ventilated. None died, but see report 936. None had been admitted with Covid in 2020. Report 24 August

944. An unnamed pregnant woman died from Covid at Broward Health Medical Center, Miami, Florida recently (click here). This location suggests this was not Greyzie Miller report 980, but it could be Kristen McMullen report 882. Report 24 August

943. Gabriella Nardi-McGee, from New York got vaccinated at 12 weeks. She is now 24 weeks (click here). In the same report an unnamed pregnant woman with Covid delivered preterm, and spent months seriously Ill in ICU in Ronald Reagan UCLA Medical Center in Los Angeles. She was unvaccinated but recovered. Also in the same report Molly Wadzeck Kraus from Trumansburg, New York got vaccinated while pregnant and gave birth to a healthy baby girl. Report 23 August

942. Islay Mactaggart, 36, had her two vaccine doses at 14 and 26 weeks gestation (click here). She is now 28 weeks. Report 21 August. Vaccine in pregnancy news report

941. Haley Mulkey Richardson, 32, a nurse from Theodore, Alabama, was due in November. She contracted Covid in July, was admitted to hospital early in August, and died on 20 August. Her baby had died two days earlier (click here). She had not been vaccinated. Report 25 August

22 August 2021

940. Mahima Mathew, 23, from Kanjirappally, Kerala, India, who was seven weeks pregnant, was vaccinated on 6 August. On 15 August she became seriously ill, and was admitted to a private hospital in Pala. She died on 20 August (click here and here). The postmortem report cited brain haemorrage as the cause of death and the death certificate cited COVID-19 vaccine as a contributory cause. The type of vaccine she received is not stated. Reports 22 August Vaccine in pregnancy news report Update 27 August. Reported on 23 August (click here) that the cause of death was cerebral venous thrombosis and vaccine-associated thrombocytopenia. Update 29 August. This report (click here) implies that she had received the Covishield (Oxford, AstraZeneca) vaccine.

939. Kameron Fischer, 24, of Quincy, Illinois, contracted COVID-19 on July 15 at 29 weeks (click here). She required 8 days intensive care at HSHS St. John’s Hospital in Springfield, and recovered. The pregnancy is ongoing. She had not been vaccinated. Report 22 August

938. An unnamed pregnant woman, age 37, from Colombia, gave birth by Caesarean and died on 11 August from Covid at the Cabueñes Hospital, Gijon, Spain (click here). Report 22 August

937. An unnamed woman with Covid was admitted to the intensive care unit of Petah Tikva’s Beilinson Medical Center, Israel, shortly after giving birth (click here). She was unvaccinated. Outcome not reported. Report 22 August

936. Samantha Willis, 35, from Derry, Northern Ireland, contracted Covid while pregnant and died on August 20, at Altnagelvin Hospital (click here). Her baby survived. Report 22 August.

21 August 2021

935. Amy Shedon, 29, from Girvan, Scotland, got vaccinated at 32 week and gave birth to a healthy boy in April (click here). Report 18 August. Vaccine in pregnancy news report

934. The unnamed wife of Dr. Omar Ibrahimi got the Moderna vaccine at 11 weeks and give birth normally (click here). Report 16 August. Vaccine in pregnancy news report

933. An unnamed woman died of Covid on 16 August at Virgen del Rocio university hospital in Seville, Andalucia, Spain, shortly after giving birth (click here). She had not been vaccinated. The baby is healthy. In the same report 44 pregnant woman have been admitted to hospital in the region, and seven are in intensive care. Report 20 August

932. An unnamed policewoman from Banga, South Cotabato, in the Philippines, contracted Covid and was delivered by Caesarean on 10 August (click here). She died about 3 days later. The baby is healthy. Report 19 August

931. Thirty nine COVID-positive pregnant women were admitted to the University of Alabama at Birmingham Hospital in August. (click here). On the 19 August, ten were in intensive care and seven on ventilators. In the same report Dr Jessica Grayson, got the Pfizer vaccine at 21 weeks in December, and gave birth normally in April. Report 20 August. Vaccine in pregnancy news report

930. Ninety four pregnant women have tested positive for coronavirus in 2021, in Tanah Datar District, West Sumatra, and one has died (click here). Report 20 August

929. 1,754 pregnant women have been vaccinated in Jakarta, Indonesia (click here). Report 19 August Vaccine in pregnancy news report

928. Paige Ruiz, from Fort Worth, Texas contracted Covid and gave birth by Caesarean section on August 2nd (click here). She died on 15 August. She had not been vaccinated. Report 13 August

927. Lacresanna Williams, 21, from Shreveport, Louisiana, contracted covid, gave birth by Caesarean and died (click here). The baby survivied. She had not been vaccinated. Report 19 August

926. An unnamed woman in her 30s with Covid, in Kashiwa, Chiba Prefecture, Japan, was unable to find a hospital to give birth in and delivered at home at 29 weeks (click here or here). Her baby died. Report 20 August. Vaccine in pregnancy news report

925. Between two and five pregnant women are currently being admitted to Jupiter Medical Center in Florida each day due to COVID-19 (click here). Report 19 August

924. An unnamed pregnant woman was treated with ECMO at a hospital in Yale (click here). The baby died and the mother’s outcome was not known. Report 16 August

923. Kelly Lawler, TV critic for USA TODAY, got the first dose of the Pfizer vaccine at five weeks and the second at 9 weeks (click here). She is now six months and the pregnancy is ongoing. Report undated but Google says 20 August. Vaccine in pregnancy news report

922. Aimee Styles had the Pfizer vaccination at 14 weeks pregnant, and Emily Reed had her first dose at 8 weeks and second at 22 weeks (click here). Report 18 August Vaccine in pregnancy news report

921. Yuranis De Radomska Munoz got vaccinated at 32 weeks, at the Jessop Wing maternity unit in Sheffield (click here). Report 14 August Vaccine in pregnancy news report

920. Zara Zuckerman, got vaccinated while pregnant, or soon after; the article is ambiguous (click here). Report 18 August Vaccine in pregnancy news report

919. Vanessa Alfermann, 32, a nurse at Missouri Baptist Medical Center in St. Louis, contracted covid at 20 weeks, in November 2020, and miscarried (click here). Report 21 August

918. Jane, 34, tested positive in late pregnancy and gave birth normally at the Colonial War Memorial Hospital in Suva, Fiji (click here). Two unnamed pregnant woman are also reported to have died in Fiji in July. Grace Holmes Tui, 26, who is expecting her second child in October, got the Moderna vaccine. Report 20 August Vaccine in pregnancy news report

18 August 2021News Reports 547 & 780 also updated

917. Melissa Jones from Pensacola, Florida, got vaccinated in March and gave birth early in August (click here). Report 17 August. Vaccine in pregnancy news report

916. Clara, from Norwich, UK, had both doses of the vaccine while pregnant (click here). Report 18 August. Vaccine in pregnancy news report

915. An unnamed woman with covid gave birth at Mercy Hospital, Bakersfield, California recently (click here). Her baby is currently in the NICU, and may be infected with Covid. Report 18 August

914. An unnamed woman from Central Texas contracted covid while pregnant with twins (click here). She recovered but both twins died on 20 July. Report 17 August

17 August 2021

913. An unnamed pregnant woman from Valladolid, Negros Occidental, the Philippines, contracted Covid on 2 July and was treated at Corazon Locsin Montelibano Memorial Regional Hospital (click here). Sher and the baby recovered. Report 16 August

912. Shantel Feliciano from Volusia County, Florida, contracted Covid on 6 August at term and was delivered by Caesarean (click here). She remains sedated in hospital. The baby is home. Report 16 August

911. Anti-vaccine protestors invaded a special pop-up vaccination clinic for pregnant women in the Foyle arena in Londonderry, Northern Ireland, on 14 August (click here). Report 16 August. Vaccine in pregnancy news report

910. Yahaira Gallardo-Martinez, 25, of Dallas, got vaccinated in January and gave birth to a baby girl on August 6 at Parkland hospital (click here). Courtney Johnson of Dallas, 37, a nurse practitioner, gave birth on May 28 and has been vaccinated. Report 16 August. Vaccine in pregnancy news report

909. Carolina Martinez, 32, contracted Covid on 28 April in the 2nd trimester (click here). She required ventilation at Ascension Seton Medical Center in Austin from then until 2 June, and remains on oxygen therapy. She is due to give birth at the end of August. She had not been vaccinated. Report 16 August

908. Greyzie Miller, 31, from Jacksonville, Florida, contracted Covid at 31 weeks and was delivered by Caesarean at 32 weeks (click here). Following 19 days ventilation she died on 15 August. She had not been vaccinated. The baby survived. Report 16 August

907. There have been 900 new COVID-19 cases in pregnant women in Alberta since April (click here). Two are presently in ICU and one unnamed woman is on a ventilator. In the same report Annalise Klingbell, 33, and Kielan Buzzard, who are both due in November got vaccinated. Report 16 August Vaccine in pregnancy news report

906. There were 27 pregnant women with Covid in Los Angeles County in the week ending June 27, and 81 during the week ending July 25 (click here). There have been 11,264 confirmed COVID cases among pregnant women in the county as of Aug. 10, the vast majority of them Latina. Twelve women who tested positive have died. Report 16 August

16 August 2021

905. One unnamed pregnant staff member contracted covid at the Sultanah Bahiyah Hospital in Alor Setar, Kedah, Malaysia (click here). Report 16 August

904. Amandeep Kaur Khosa, 48, from Haryana, India, contracted Covid while pregnant with IVF twins (click here). She was delivered by Caesarean on 25 May at 26 weeks. Mother and both twins recovered. Report 15 August.

903. An unnamed pregnant woman, age 32, from Barangay Sum-ag, the Philippines, swabbed postive on 19 July (click here). Report 16 August

902. Dr P Shanmugapriya, 32, of Anuppanadi Urban Primary Health Centre, Madurai, India, died of Covid on 8 May, at Government Rajaji Hospital, at eight months gestation (click here). The baby’s outcome was not reported. Report 16 August

901. Ashley Tunnel, 30, from Benton. Tennessee contracted Covid on 23 July. Her baby died at about 22 weeks (click here). She required ventilation at Vanderbilt University Medical Center’s ICU, and is recovering. Report 15 August

900. Avila Geraldine Samuel from Malaysia got vaccinated during pregnancy (click here). Report 16 August

899. Two unnamed pregnant women died of Covid in the last week in Mississippi (click here). One was a 32-year-old woman with very few health conditions delivered by Caesarean at an unnamed hospital at 32 weeks. Her partner also died of covid, but the baby is doing fine. No details given of the other maternal death. In the same report another unnamed women with Covid delivered at 34 weeks and the baby died. Yet another unnamed 27-year-old woman with Covid required ICU treatment, and on 10 August ventilation which is ongoing. Her baby is alive. None of these women had been vaccinated. Report 13 August.

15 August 2021

898. Iftiyah [first name only], age 25, w/o Afrizal, from Bekasi, Indonesia, contracted Covid at 30 weeks and was delivered by Caesarean on 11 July at a hospital in Yogyakarta (click here). She died on 22 July. The same report states that there have been at least 85 maternal deaths, of which nearly 70% were due to Covid, in Central Java’s regencies of Grobogan and Banyumas this year. Report 15 August.

897. Carrie Johnson, 33, wife of Britain’s Prime minister Boris, has had both doses of either the Pfizer or Moderna vaccine (click here). She is due to give birth in December, which would make her about 20 weeks now. She is reportedly “feeling great”. Report 15 August. Vaccine in pregnancy news report

14 August 2021

896. Chelsea Harman, from Florida, contracted severe Covid on 2 August, required ventilation and delivered preterm (click here). She is now extubated, and her and the baby are recovering. She had not been vaccinated. Report 13 August

13 August 2021

895. Paulinda Inocencio, from Bastrop. Texas, contracted Covid in the third trimester and required ventilation and delivery by Caesarean (click here). Mother and baby are recovering. She had not been vaccinated. Report 12 August

894. An unnamed 37 year old woman from Nadi, Fiji, died from Covid in Lautoka Hospital on 7 August shortly after giving birth (click here). She had not been vaccinated.

893. Grayson Bakes, 21, from Utah contracted severe Covid and gave birth by Caesarean in August (click here). She remains on a ventilator. She had not been vaccinated. Report 12 August

892. 95 pregnant women contracted Covid last week in Ireland (click here). Report 13 August.

891. Alexa Sheeder, from Davenport Illinois, contracted COVID-19 on July 25 and gave birth on July 28 (click here). Her condition deteriorated. She was ventilated on 7 August and died on 10 August. She had not been vaccinated. Report 13 August

890. Katelyn Huber, from St Louis, Missouri, got vaccinated while pregnant and gave birth to a healthy baby (click here). Report 10 August Vaccine in pregnancy news report

889. Ashlee Caldwell, from Payson, Arizona, contracted Covid in July and gave birth at 30 weeks gestation (click here). She had not been vaccinated. Her baby remains in intensive care. Report 11 August

888. Braxten Goodwin, 24, from North Kansas City, died of COVID-19 on 2 August, two weeks after giving birth at 6 or 7 months gestation (click here). She had not been vaccinated. The baby is alive but has been transferred to Children’s Mercy hospital. Report 12 August

887. Cierra Chubb, 33, contracted Covid at 38 weeks and was delivered by caesarean (click here). Her baby is healthy, but she remains on a ventilator in an unnamed hospital South Carolina. She had not been vaccinated. Report 12 August Inadvertent duplicate of NR 868 deleted 9 September.

886. An unnamed woman tested positive after giving birth in Auburn hospital, Sydney (click here). Report 12 August.

885. Laura Curtis contracted severe Covid at 21 weeks and spent 17 days on a ventilator. She recovered and gave birth at the Rotunda Hospital, Dublin on 14 July (click here). Report 11 August

884. An unnamed woman aged 29 contracted severe Covid while pregnant with triplets at 28 weeks (click here). She was delivered by Caesarean on 11 August at a designated hospital in southwest China’s border city of Ruili. The babies are in stable condition. The mother’s condition is not reported. Report 12 August.

883. Siti Sarah Raisuddin, a Malaysian singer, contracted severe Covid at 32 weeks, and was delivered by Caesarean while ventilated (click here). She died at the Universiti Kebangsaan Malaysia Medical Centre, a few days later. Report 10 August

882. Kristen McMullen, age 30, from Florida, contracted Covid and was delivered by Caesarean on July 23 (click here). She died from Covid on 6 August. Her vaccine status was not revealed. Her baby is healthy. Report 12 August

881. In February an unnamed woman got the BioNTech vaccine in Pennsylvania at 35 weeks (click here). Raeshel Contreras, age 33, had not yet decided at 28 weeks – she planned to decide by 30 weeks. Tista Banerjee did not get vaccinated and gave birth to twins in June. She got vaccinated in July. Report 12 August. Vaccine in pregnancy news report

8 August 2021

880. An unnamed pregnant woman, 35, from the Kanto region of Japan, who was due in September, got vaccinated on 9 July (click here). Report 8 August. Vaccine in pregnancy news report

879. Kassidy Hazelton, 37, contracted Covid in May at 5 months gestation and delivered on May 31 by Caesarean (click here). She was seriously ill, and spent seven weeks in Banner University Medical Center, Arizona. She had not been vaccinated. Report 8 August

7 August 2021

878. Hung Vuong Hospital, in Ho Chi Minh City, Vitenam has treated up to [sic] 120 pregnant women with Covid in the past week (click here). Tu Du Hospital, in the same city, has recently treated more than 70. Report 6 August.

877. An unnamed woman with Covid, treated by Halifax OBGYN in Daytona Beach, Florida, required delivery by Caesarean and ventilation (click here). No further details. Report 6 August

876. Colleen Bonds, 36, from Honolulu, contracted Covid, required ventilation and was delivered by Caesarean on 25 July at 28 weeks (click here). She had not been vaccinated. Report 6 August

875. Claudia Li, 30, from Birmingham, UK, contracted Covid at 24 weeks, and required ventilation, and delivery by Caesarean at 26 weeks, on 30 July (click here). She has recovered. Her baby remains in intensive care. She had not been vaccinated. Report 7 August

874. The Belfast Trust hospitals (Royal Victoria, Belfast City, Mater, Musgrave Park, Children’s, Royal Maternity, Forster Green & Knockbracken) treated 12 pregnant or recently pregnant women for Covid last week (click here). Three are in ITU. Report 7 August.

6 August 2021

873. Danielle Chisolm from Rochester, New York, got vaccinated at 7 months gestation (click here). Report 5 August

872. An unnamed woman from Nueces County, Texas died from Covid a week after giving birth (click here). She had not been vaccinated. Nueces County is about 600 km from Taylor County, so this is unlikely to be the same woman as in reports 843 & 870. 6 August.

5 August 2021

871. Nurse Beth Borkowski from Madison, Wisconsin, received both Covid vaccine doses before becoming pregnant (click here). Report 4 August. Vaccine in pregnancy news report

870. An unnamed woman in her 20s, from Taylor County, Texas, who had recently given birth, died from Covid in the last week (click here). Taylor County includes the town of Abilene, so this may be the same woman who was reported to be seriously ill on 30 July Report 843. Report 5 August

869. Kristy Callaway, from Corpus Christi, Texas, contracted Covid during her pregnancy (click here). Her son was healthy, but caught Covid age 5 months. Report 5 August

868. Cierra Chubb, 33, contracted Covid and gave birth by Caesarean at 33 weeks on July 26 (click here). She is currently being ventilated in ICU in Columbia, South Carolina. She had not been vaccinated. Report 5 August

867. Labour MP, Stella Creasy, 44, has had both doses of the vaccine while pregnant (click here). Report 31 July. Vaccine in pregnancy news report

866. Megan Jackson, from Asheville, North Carolina, got vaccinated at eight weeks gestation (click here). Her pregnancy is ongoing. Juliann May also got vaccinated during pregnancy. Report 4 August. Vaccine in pregnancy news report

865. On Monday 26 July, 114 pregnant and five lactating women were vaccinated in Bengaluru, India (click here). Report 30 July. Vaccine in pregnancy news report

864. Since 15 July, 234 pregnant women have been vaccinated in Mumbai (click here). One unnamed 24-year-old woman, who had received two doses of Covaxin, developed fever, vomiting, cough, headache and swollen gums. She recovered. Report 29 July. Vaccine in pregnancy news report

863. Valerie Manring, from Texas, received her first does of vaccine during pregnancy. She is now 26 weeks (click here). Report 3rd August. Vaccine in pregnancy news report

862. Erin Gloria Ryan got vaccinated during pregnancy (click here). She is now in the third trimester. Report 1 August. Vaccine in pregnancy news report

861. Maria Garza, from Texas, got vaccinated during pregnancy and gave birth normally on July 19 (click here). Her husband had contracted Covid in February and died of it in June 2021. Report 4 August. Vaccine in pregnancy news report Inadvertent duplicate of NR 828. Deleted 24 October

860. Sarah Brown, age 36, contracted Covid at 33 weeks, and required ITU treatment at Vanderbilt University Medical Center in Nashville (click here). She recovered and the pregnancy is ongoing. She had not been vaccinated. Report 5 August.

859. Kristen Hutton from Palm Beach Gardens, Florida, got covid at 39 weeks and was delivered by Caesarean (click here). She spent 4 days in ICU but recovered. Her baby was fine. She had not been vaccinated. Report 30 July

858. Jodie Wilkinson, from Norwich, got vaccinated at 25 weeks and gave birth in May (click here). Laura Palmer, age 26, from Hingham, got vaccinated and her pregnancy is ongoing. Report 31 July. Vaccine in pregnancy news report

857. Nazia Akhtar, from Ashton, UK, got vaccinated while pregnant and gave birth normally in June 2021 (click here). Report 2 August. Vaccine in pregnancy news report

856. Mariecen Nituma Agillon, ang 26, contracted Covid at 31 weeks and her twins were delivered by Caesarean at 32 weeks at NMC Specialty Hospital, Al Nahda, Dubai (click here). She and the babies recovered. Report 3 August

855. Laura Brunton from Witney in Oxfordshire, got vaccinated while pregnant (click here). Her pregnancy is ongoing. Report 30 July. Vaccine in pregnancy news report

854. Portia Hayes had severe Covid and required ITU care and Caesarean birth at 27 weeks University of Mississippi Medical Center (click here). She recovered but suffered many complications. She had not been vaccinated. Her baby survived. Another unnamed pregnant woman is currently severely ill in the same unit. Report 3 August

853. In Catalunya, Spain, 549 pregnant women have been admitted to hospital after testing positive for Covid-19 so far in 2021. 52 required intensive care but all survived (click here). Report 5 August

852. Colleen Grande from Austin, Texas got the vaccine early on in her pregnancy which is ongoing (click here). Report 4 August. Vaccine in pregnancy news report

851. Three pregnant women died from Covid-19 in July in Spain (click here). One each in Barcelona, Málaga and Murcia. The patient from Murcia was probably also reported in sources 807 and 838. Report 2 August

850. Lydia Stephens, from the Rhondda in Wales got both doses of the vaccine prior to 30 weeks, and her pregnancy is ongoing (click here). Up to 22 July, around 1,677 pregnant women in Wales had had the vaccine. Report 4 August. Vaccine in pregnancy news report

1 August 2021

849. Stacey Knights, age 27, from Middlesborough, UK, contracted Covid in January 2021, at 12 weeks gestation (click here). She recovered. Report 31 July

848. Suma (an alias), age 37, contracted Covid, and gave birth at 31 weeks, while on a ventilator at Apollo Hospitals in Bengaluru, India (click here). She spent 36 days on ECMO, and a further 19 in ICU, but recovered. The baby also survived. Report 1 August.

847. Lorena Betancourt, age 26, from Argentina, gave birth with Covid and spent a month in intensive care (click here). She died on July 15. Her daughter survived. Report 1 August

31 July 2021

846. Over 227,000 pregnant women have received their first dose of anti-coronavirus vaccine in India (click here). 78,838 in Tamil Nadu, 34,228 Andhra Pradesh, 29,821 Odisha, 21,842 Madhya Pradesh, 18,423 Kerala and 16,673 in Karnataka. Report 30 July. Vaccine in pregnancy news report

845. Zoey Edwards, 32, from Preston contracted Covid. and was admitted to ITU at Royal Preston Hospital and delivered by Caesarean both on June 25 at 35 weeks (click here). She had not been vaccinated. She and the baby survived. Report 31 July.

844. Dr. Jane Martin from Ochsner Health in Louisiana, got vaccinated in the 34th and 37th weeks of her recent pregnancy and gave birth to a healthy baby (click here). Report 31 July. Vaccine in pregnancy news report

30 July 2021

843. An unnamed woman, aged less than 30, who recently gave birth, is now seriously ill with Covid, in Hendrick Medical Center, Abilene, Texas (click here). Report 30 July

842. Dr. Rebecca MacDonell-Yilmaz got the Pfizer-BioNTech vaccine while pregnant (click here). Report 29 July Vaccine in pregnancy news report

29 July 2021

841. Imogen, 29, from Brighton got vaccinated in the second trimester (click here). Report 29 July Vaccine in pregnancy news report

840. Carrie Limon contracted Covid and gave birth at Sutter Roseville Medical Center, California, on May 7 (click here). Her son required NICU treatment, and she required ECMO, but both survived. She had not been vaccinated. Report 29 July

28 July 2021

839. Former olympic gymnast Shawn Johnson, age 29, tested positive for COVID-19 early in pregnancy and recovered (click here). She gave birth to a healthy baby by Caesarean on 19 July. Report 28 July.

838. An unnamed a 40-year-old woman with severe Covid gave birth two weeks ago in ICU in Murcia, Spain (click here). She died on 27 July. She is probably one of the women reported in source 807. Report 28 July

837. An unnamed woman with Covid was delivered by Caesarean at James Cook hospital in Middlesbrough this week (click here). The baby is doing fine. The mother remains ventilated. Report 28 July

836. Dr Gesti Wira Nugrayekti, age 25, who was training in anesthesiology at Airlangga University in Surabaya, contracted Covid and gave birth prematurely early in July (click here). Three weeks after the birth she died. She had not been vaccinated. In the same report, Indiana Alawasilah, age 33, from Bandung, contracted Covid during the third trimester in 2020. She required oxygen therapy but recovered. Report 28 July

835. Patience Atuhaire contracted Covid at 8 months gestation (click here). She was delivered by caesarean at Mulago Hospital, Uganda in February 2021, and required ICU treatment. Her and the baby survived. Report 27 July

834. Supraja Reddy Yeruva, age 27, got Covid in pregnancy in June and required ICU care at a private hospital in Hyderabad (click here). A month later she remains there. Report 29 July

833. Early in the pandemic two unnamed women who gave birth at Marin Health Medical Center, became critically ill with Covid and had to be transferred to University of California, San Francisco (click here). Both survived. Report 27 July

832. Clair Griffiths, age 43, contracted Covid and gave birth to a healthy son by Caesarean on 18 July (click here). Two days later she was readmitted to hospital with pneumonia, where she remains. Report 28 July

27 July 2021

831. Emmy Rossum, age 34, star of TV comedy “Shameless” got vaccinated during pregnancy and had a healthy daughter (click here). Report 27 July Vaccine in pregnancy news report

830. An unnamed 38-year-old woman with severe Covid gave birth at Barzilai Medical Center in Ashkelon, Israel, on 24 July (click here). Her daughter is fine but the mother’s condition deteriorated and she is presently on ECMO at the Wolfson Medical Center in Holon. She had not been vaccinated. Report 25 July.

829. Gemma Wilkinson, 38, got her first vaccination dose late in pregnancy and gave birth to a hea;thy girl (click here). She had her second dose while breastfeeding. Report 27 July. Vaccine in pregnancy news report

25 July 2021

828. Maria Garza, from Leander, Texas got vaccinated while pregnant in February 2021 and gave birth normally in July (click here). She had previously had mild Covid in 2020, and her husband had died of Covid in February 2021. Report 24 July. Vaccine in pregnancy news report

24 July 2021

827. Glorimar required long term ICU care at Wesley Medical Center, Wichita, Kansa, while she was pregnant and gave birth nearly a year ago (click here). Mother and baby recovered. Report 24 July

826. At Christmas 2020, Sally, age 38, contracted Covid at 20 weeks (click here). The pregnancy outcome was not reported. Report 24 July

22 July 2021

825. An unnamed woman died shortly after giving birth in Ndola Teaching Hospital, Zambia (click here). Her cause of death and Covid status were not reported, but her partner had died of Covid three days earlier. Report 22 July

824. In Thailand, between December 2020 and July 3rd 2021, 581 pregnant women contracted coronavirus and nine died. 40 babies were born infected and four died. (click here). Report 22 July

823. Three unnamed pregnant woman, and two who have recently given birth, are currently hospitalised in Israel with Covid (click here). All are “in good condition”. Report 22 July

21 July 2021

822. Violinist Izzy Judd tested positive for SARS-CoV-2 early in her third pregnancy (click here). She recovered and the pregnancy is ongoing. Report 21 July

20 July 2021

821. More than 100 pregnant women were admitted to hospital in each of the last two weeks [presumably weeks ending 2nd & 9th July] with COVID-19. No pregnant women who had received both doses of vaccine have been admitted to hospital since the vaccination programme began. Only five women admitted have received a single dose (click here). Report 15 July. Vaccine in pregnancy news report.

821. Peru is prioritizing pregnant women in its vaccination campaign (click here). Report 13 June Vaccine in pregnancy news report.

19 July 2021

820. Anshuma Chauhan, 30, died from Covid in April shortly after giving birth by Caesarean in Delhi, India (click here). Report 8 June.

819. Eight unnamed pregnant women died of Covid in Uruguay between April 29 and June 8 (click here). Report 2 July

818. Elisabeth Soto, 38, died from Covid on 19 April, six days after giving birth in Lomas de Zamora, Argentina (click here). Report 9 July

817. Oksana Shelomentseva had severe Covid and gave birth by Caesarean at 32 weeks in Irkutsk, Russia (click here). She required 51 days ventilation in ICU, but survived. Her baby also survived. Report 12 Jan 2021

816. Helen Singh, 22, from Fiji, contracted Covid on 22 June and gave birth soon after (click here). Mother and baby recovered. Report 19 July

18 July 2021

815. An unnamed 33-year-old woman in Thessaloniki, Greece, has Covid in her 6th month of pregnancy, and is being ventilated (click here). Report 18 July

814. Thirty three pregnant women died from Covid in Nepal between March 2020 and June 2021 (click here). Report 18 July

813. Dr Amy Manos age 31, from New South Wales, Australia, got vaccinated at 26 weeks gestation (click here). She is due in September. Report 18 July. Vaccine in pregnancy news report.

812. Angela MacDonald got vaccinated in April two weeks after giving birth (click here). Report 18 July Vaccine in pregnancy news report.

14 July 2021

811. About 150 pregnant women have tested positive in Fiji (click here). None have died. Report 14 July

810. An unnamed 22-year-old pregnant woman with Covid-19 is intubated at Nicosia General Hospital, Cyprus (click here). Report 14 July

13 July 2021

809. Vong Daneth, age 29, from Cambodia, contracted Covid at 7 months and was delivered by Caesarean (click here). She died but her baby survived. Report 13 July

808. Rakhi Mandal Biswas, age 31 contracted covid and was delivered by Caesarean at Kolkata Medical College and Hospital, at 32 weeks, on 21st June (click here). She died, but the baby survived. Report 13 July

807. Two unnamed women, aged 29 and 40, with Covid, one pregnant and one recently delivered are in ITU in Hospital Clínico Universitario Virgen de la Arrixaca, El Palmar, Murcia, Spain (click here). Both are reportedly on ECMO. The baby who has been delivered is alive. Report 13 July

806. Sophie Forrester, 28, contracted Covid and gave birth by Caesarean on on July 6 at Forth Valley Royal Hospital (click here). Mother and baby recovered. Report 13 July

12 July 2021

805. Shubha Deshmukh got vaccinated at eight months gestation in Pune, India (click here). Report 12 July Vaccine in pregnancy news report.

804. Vanessa de Oliveira Silverio, age 33, from São José dos Campos, in São Paulo state contracted Covid at 34 weeks and died during a Caesarean birth in March 2021 (click here). Her baby survived. Fabiana Alves Sousa, age 31, from Ceará state in the north-east Brazil also contracted Covid and was delivered by Caesarean at 30 weeks. Both mother and baby survived. Report 12 July

11 July 2021

803. An unnamed woman, age 22, with HIV and Covid-19, gave birth at Diphu Medical College and Hospital, Assam, India on 9 July (click here). A woman named SR Das, also with covid, gave birth the same day. Both babies are healthy. Report 11 July

7 July 2021

802. Kalyani Agrahari contracted Covid at 32 weeks (click here). She was admitted to Mahila Chikitsalaya (Women’s hospital) in Jaunpur, and died on April 24. The baby’s outcome is not reported. Report 9 June

801. Sari Azalea Yuliani, age 24, contracted Covid at 37 weeks (click here). She was delivered by Caesarean at Dr Esnawan Antariksa Air Force Hospital, Jakarta, on 30 June, and died two days later. Her baby tested negative, but had other complications from the birth, and also died. The report also states that, according to the Indonesian Obstetrics and Gynaecology Association (POGI), more than 500 pregnant women have tested positive since the pandemic began, with 4.5% needing ICU treatment, and about 3% dying as a result of the disease. Report 7 July

6 July 2021

800. Kavisha Patel (a pseudonym) died from Covid in June, after giving birth at 32 weeks in Ahmedabad, India (click here). The baby survived. Report 1 July.

799. Ashton Reed, 25, contracted Covid-19 at 30 weeks gestation (click here). She required ECMO at University of Arkansas for Medical Sciences (see source 795) and gave birth by Caesarean on May 27.  Mother and baby survived. Report 29 June.

798. Between 1 April 2021 and 30 June 2021 the Mother & Child Hospital at Silchar Medical College in Assam has cared for 160 pregnant women with Covid (click here). Of 82 births, 43 were by Caesarean. There were two Covid-related deaths; report unclear if these were of mothers or babies. Report 1 July

797. An unnamed woman tested positive at 24 weeks gestation in April (click here). She gave birth by Caesarean at the Government Medical College & Hospital, Nagpur, India on 20 June. The baby weighed 2.3 kg, was preterm, had congenital heart disease, tested positive for Covid and died age 8 days. Report 4 July

796. Amrita Sundareswaran contracted Covid-19 at six weeks gestation and recovered (click here). She gave birth by Caesarean on 26 April and her baby developed breathing difficulties. The baby had anti-Covid antibodies and recovered. Report 4 July

1 July 2021

795. Three unnamed pregnant woman at University of Arkansas for Medical Sciences were on ECMO last week (click here). Report 30 June

794. Elizabeth Etherington, 40, received her second dose of the Pfizer vaccine at 34 weeks (click here). Report 24 June. Vaccine in pregnancy news report

793. Olivia Saxton got vaccinated in January. She conceived naturally in March and had her second dose at 13 weeks (click here). The pregnancy is ongoing. Report 30 June Vaccine in pregnancy news report

30 June 2021

792. Claudia Edwards, age 35, died from Covid at Princess Margaret Hospital in the Bahamas in May, the day after giving birth (click here). Report 30 June

29 June 2021

791. An unnamed woman with Covid-19 gave birth to a healthy baby at Soroti Regional Referral Hospital in Uganda (click here). The disease was mild and both recovered. Report 29 June

790. Since August 2020, 190 women with Covid have given birth at Maharaja Krushna Chandra Gajapati Medical College & Hospital, Brahmapur (click here). 109 were normal and 81 were Caesareans. Report 29 June.

789. Kate Barr, age 39, from Pittsburg, contracted Covid, gave birth on 13 May and died on 27 June (click here). Report 28 June

26 June 2021

788. Yesenia Lopez, age 34, from New York gave birth while on ECMO in April (click here). She and the baby recovered. Her husband had been vaccinated but she had decided against. Report 20 June. Vaccine in pregnancy news report

787. Jen Sizeland from UK got the Pfizer vaccine at 28 weeks (click here). The pregnancy is ongoing. Report 23 June Vaccine in pregnancy news report

786. Sara Edmond a clinical psychologist at the Veterans Affairs Connecticut Healthcare System contracted Covid in pregnancy (click here). Mother and baby are fine. Report 21 June

785. Puji Apriani from Kudus, Central Java, Indonesia, died undelivered from Covid-19, at Loekmono Hadi General Hospital (click here). Report 24 June

22 June 2021

784. Prum Lay, age 35, and Ul Srey Nouch, age 18, both had Covid and gave birth naturally at Poipet Referral Hospital, Cambodia (click here). Mothers and babies are fine. Report 22 June

20 June 2021

783. Angie Wells tested positive during her pregnancy but her symptoms were mild (click here). Her baby was born at home in Benoni, east of Johannesburg, and initially tested negative, but later became seriously ill and tested positive. Both survived. Report 20 June

782. Manju, wife of Bharat Sharma, gave birth on 21 April and died of Covid on 29 ASpril (click here). Her baby survived. Daksha w/o Devdutt Taviyad, gave birth on 19 May and died of Covid complications on May 30. The unnamed wife of Nitin Sodha also died of Covid during or after her pregnancy. All three babies survived. Report 20 June.

781. Thrupathamma, aged 21, had severe Covid-19 symptoms and gave birth by Caesarean at 37 weeks at Continental Hospital, Hyderabad, India (click here). She was treated in ICU. Her baby survived. Both tested negative. Report 20 June.

19 June 2021

780. Hunter McGrady, age 28, a plus size model in the United States, contracted Covid at seven months (click here). She recovered and the pregnancy is ongoing. Report 12 June. Update 8 July. She had a healthy baby (click here). Update 18 August (click here). She got vaccinated after the birth.

779. Priyali Sur, a Delhi-based journalist, contracted Covid in the 2nd trimester of pregnancy (click here). She recovered. Report 15 June

778. Rehab, the wife of Altuf Shamsi, who had severe Covid gave birth by Casarean on 29 April, and died of Covid complications on 11 May, in India (click here). Report 14 June

777. Thais Ferreira de Lomes required ventilation for Covid and gave birth at 28 weeks at the Grajau Hospital in Sao Paulo in March (click here). That hospital has observed at least one pregnant woman with Covid each week in 2021. Mother and baby survived. Report 18 June

776. Vidya Justin (age 25) of Korampallam gave birth to triplets by Caesarean at 32 weeks, Thoothukudi Medical College Hospital, in India, on 30 May (click here). She had Covid-19 and HELLP syndrome with liver and kidney failure, and was treated in ICU. She and the babies recovered. Report 16 June

775. An unnamed woman with Covid gave birth to twins on 17 June in Cambodia (click here). Both babies are healthy as is the sick mother. Report 18 June.

774. An unnamed woman age 36 with Covid gave birth in Tacloban city in the Philippines on 17 June (click here). Mother and baby are doing fine. Report 18 June

14 June 2021

773. An unnamed woman with Covid-19 gave birth to twins at six months gestation at the Western Visayas Medical Center in Mandurriao district, the Philippines, on 9 June (click here). The twins died the same day. Report 14 June

772. Dana Sy, age 27, tested positive for Covid-19 when she gave birth in July 2020 at the Chinese General Hospital and Medical Center in Manila (click here). Her baby was separated from her for a period. Both recovered. Report 14 June

771. Smita Panda, age 28, a staff nurse at the Acharya Harihara Cancer hospital in Cuttack, Odisha, India, got Covid-19 at 9 months gestation and gave birth on 22 April (click here). Seven days later she died of Covid, and a little later her husband died too. The baby survived. Report 14 June

770. Playback singer Shreya Ghoshal gave birth on 22 May and got vaccinated on 14 June (click here). Report 14 June. Vaccine in pregnancy news report

13 June 2021

769. Actress, Adite Malik, gave birth in March and got vacccinated in Mumbai, in June (click here). Report 13 June. Vaccine in pregnancy news report

768. Jennifer Nash from California, contracted Covid at 24 weeks in March 2021, and delivered by Caesarean at 29 weeks on 3 May (click here). She was cared for at Ronald Reagan UCLA Medical Center, and treated with ECMO. She came off the ECMO but remains in ICU. Report 13 June

767. Lindsay Bullock contracted Covid at 36 weeks and gave birth by Caesarean on 23 February at Yale New Haven Hospital (click here). She was ventilated for a week. Mother and baby recovered. Report 12 June

11 June 2021

766. Since May, 24 pregnant women with Covid have delivered at the District Hospital, Brandipora, Jammu and Kashmir, India (click here). Report 11 June

765. Nor Baizura Mohd Noordin contracted Covid in December 2020, and was admitted to ICU at Universiti Malaya Medical Centre, but not ventilated. She recovered, and gave birth two months later (click here). Report 10 June

764. An unnamed woman with Covid-19 was delivered by Caesarean on 10 June, at King George Hospital in Vizag, Andra Pradesh, India (click here). The mother had been on a ventilator for ten days and remains so. The baby is alive. According to the article, 28 pregnant women with Covid are currently in the same hopsital. Last month the figure was 90. Report 10 June

10 June 2021

763. April Mager contracted Covid-19 at just 4 weeks gestation and spent nine days in hospital (click here). She recovered but the pregnancy miscarried. Report 9 June

762. Natalia Worek, a nurse from Ontario, contracted Covid in the 3rd trimester, was delivered by Caesarean, and spent time in ICU (click here). Mother and baby both recovered. Report 9 June

9 June 2021

761. Shanetta Wilson contracted Covid in April at 6 months gestation, and after prolonged intensive care at George Washington University Hospital in Washington DC, died on 1 June (click here). She had not been vaccinated. Her baby had been delivered in May but had died age five days. Report 8 June

760. Dr Arfa Sajadin from West Bengal, contracted severe covid at 37 weeks, and required 10 days ventilation (click here). Mother and baby survived. Report 8 June.

759. KK Women’s and Children’s Hospital in Singapore vaccinated six pregnant women on June 8 (click here). They included Suzanna Farid Tang Shu Ling and Noriyah Abdul Rahman. Report 9 June. Vaccine in pregnancy news report.

758. Rebecca Benson from Maguiresbridge, Northern Ireland, gave birth at 26 weeks on Oct 14, 2020, and contracted covid in postnatally (click here). Report 8 June

8 June 2021

757. Dr Fatihah Shahrudin has severe Covid-19 and is being treated in ICU at the Sungai Buloh Hospital in Kuala Lumpur (click here). Her baby was delivered at 29 weeks. Report 7 June

756. Lucy Angel was vaccinated at 35 weeks gestation in May and has since given birth (click here). Natalie Wright decided against at 32 weeks. Report 7 June Vaccine in pregnancy news report

7 June 2021

755. Megan von Prittwitz from El Paso, has just given birth, and is currently being treated with ECMO in an Albuquerque hospital with Covid-related pneumonia (click here). Report 1 June

754. 225 women with Covid have given birth in Agartala Government Medical College, Tripura, India (click here). Of these, 198 were in the first wave, and 27 in the second. Report 3 June

753. Linzi Watkins, contracted severe Covid-19 at 21 weeks gestation (click here). She required four days ventilation at University Hospital of Wales in Cardiff. She recovered and gave birth normally on May 26. Report 1 June

752. Antonella, from Gioia Tauro, Italy, tested positive for SARS-CoV-2 early in her pregnancy (click here). She remained asymptomatic and gave birth normally. She attributed this to the scapular of St. Dominic Savio. Report 6 June.

751. An unnamed woman with severe Covid successfully gave birth by Caesarean on 4 June, in Prey Veng province, Cambodia (click here). Report 7 June

750. Diptimayi Devi died of Covid on May 30, 2021, the day after giving birth at Maharaja Krushna Chandra Gajapati Hospital, Brahmapur, India (click here). She was an Angwanwadi worker, a type of community health carer. Report 7 June

749. Jalpa Patel from Piplaj of Anand, India, died from Covid on April 26, 2021, the day after giving birth (click here). Report 7 June

4 June 2021

748. The rate of Covid is higher in the pregnant than non-pregnant population in Russia (click here). No numbers given. Report 24 January 2021

747. Over 390 pregnant women in Russia had contracted Covid-19 by April 2020 (click here). Report 27 April 2020

3 June 2021

746. Tina Wesley from Calgary, Canade, gave birth by Caesarean on 26 April while ventilated (click here). Report 2 June

745. Deeptimayee Devi died from Covid on 31 May, the day after giving birth at MKCG Medical College and Hospital in Bramapur, India (click here). Report 2 June

744. Briana Mike from Germantown, Maryland gave birth on 25 May after weeks on a ventilator at the University of Maryland Hospital in Baltimore (click here). Report 3 June

1 June 2021

743. Amila Khatun had Covid-19 and gave birth at Biswanath Civil Hospital, Assam, India, on 31 May (click here). Report 1 June

742. An unnamed woman from Darsheth village in Palghar district, Maharashtra, India, tested negative but her baby tested positive (click here). Report 1 June

741. Ruchi Panchal had Covid-19 and died during delivery by Caesarean section on 11 May at Surat District hospital in Gujarat, India (click here). The baby survived. Report 1 June

29 May 2021

740. Laura Durcan was vaccinated during pregnancy and gave birth normally (click here). Report 29 May. Vaccine in pregnancy news report

739. Natalia Worek contracted Covid-19 at 32 weeks and was delivered by Caesarean at St. Joseph’s Healthcare in Hamilton, Ontraio (click here). Trisha Mayer contracted it at 34 weeks and also gave birth by Caesarean. A third unnamed infected woman also gave birth by Caesarean. Report 29 May

738. Lauren Mannell tested positive the day after giving birth by Caesarean on 3 Jan 2021 (click here). Her baby was severely hypoxaemix at birth, and required cooling, but recovered. Report 29 May

28 May 2021

737. About 100 women with Covid-19 have given birth at Jawahar Lal Nehru Memorial Hospital in Srinagar (click here). Report 27 May

736. An unnamed woman gave birth at SS Hospital in Banaras Hindu University, Varanasi, Uttar Pradesh on May 25. She tested negative but the baby tested positive (click here). Report 28 May

735. Taíssa Souza, from Vitória, Brazil, died from Covid-19 three weeks after giving birth (click here). Bárbara Cesar, from the same city was pregnant with twins when she contracted Covid-18. She required three weeks ventilation. The babies were delivered by Caesarean and healthy. Report 27 May

26 May 2021

734. An unnamed woman contracted Covid-19 and gave birth safely in Karimganj Covid Hospital, Assam, on 24 May (click here). Report 26 May

733. Nine women with Covid-19 gave birth at Niloufer hospital in Hyderabad (click here). The babies initially tested negative but later tested positive. The babies recovered. Report 26 May

732. Kate Mulholland was vaccinated (Pfizer) at 33 weeks (click here). The pregnancy is ongoing. Report 26 May. Vaccine in pregnancy news reports

731. Over 200 women with Covid-19 have given birth to healthy babies in the Indian state of Jammu & Kashmir (click here). Eighty in Maternal and Child Health (MCH) Hospital, Gandhi Nagar Jammu. More than 12 in the district hospital Bandipora in Kashmir Valley. Report 25 May

730. The unnamed wife of Shailan Tiwari, who suffered from idiopathic thrombocytopaenic purpura, contracted Covid-19 while pregnant and gave birth sucessfully at Queen Mary’s Hospital in King George’s Medical University, Lucknow (click here). Report 25 May

25 May 2021

729. Bala Mounika developed Covid-19 at 28 weeks and required ventilation and delivery at KIMS Cuddles hospital in Hyderabad (click here). Both mother and baby recovered. Report 23 May

728. An unnamed women in Mandya, Karnataka, India, died from Covid-19 five days after giving birth at Mandya District Hospital (click here). Report 22 May

727. Nerissa Rego contracted Covid-19 while pregnant (click here). She recovered at home. The pregnancy is ongoing. Report 24 May

726. Fifty women with Covid-19 gave birth at Pt BD Sharma Post Graduate Institute of Medical Sciences (PGIMS) in Rohtak, India in April and May (click here). 250 such women have given birth since the start of the pandemic. 130 by Caesarean. The newborn babies were separated from their mothers. Report 25 May

20 May 2021

725. An unspecified number of women with Covid-19 gave birth at Holmes Regional Medical Center in Florida (click here). They were separated from their babies. Report 20 May

724. 29 women with Covid gave birth at the NOAH birth complex in Cebu city in the Philippines (click here). Report 20 May

723. An unnamed pregnant woman from Allalabad died from Covid-19 at the People’s Medical College in Bhopal on 5 May (click here). Her baby survived. Report 20 May.

722. An unnamed woman in the souhern Brazilian city of Tubarao received the Coronavac vaccine during pregnancy (click here). She gave birth in April. Report 20 May Vaccine in pregnancy news report

721. Szilvia Bedo-Nagy contracted Covid late in 2020 (click here). She gave birth by Caesarean in Budapest, and required ventilation, and treatment with an artificial lung, presumably ECMO. She recovered. Report 20 May

18 May 2021

720. Adriely Carneiro de Santan,a from Brazil, died from Covid-19 in September 2020, shortly after giving birth (click here). Report 7 May 2021

719. An unnamed woman in Nagpur, India, was seriously ill with Covid-19 ten days after giving birth (click here). She died the following day. Report 17 April

718. Shamili, a police inspector from Karnataka, India, contracted Covid19 at 7 months and died (click here). Report 18 May

16 May 2021

717. On April 20 a 38-week gestation, hour-old, baby at Akanksha Hospital and Research Institute (AHRI) in Anand, India, developed multisystem inflammatory syndrome in children (MIS-C) (click here). The mother tested negative but the baby had anti-Covid antibodies. The baby survived. Other similar cases are reported from SSG Hospital in Vadodara. Report 16 May

716. Sarladevi contracted Covid and gave birth at the ICU of Tilhar Medical College in India (click here). Two other unnamed women with Covid also gave birth in the ICU. One of their babies died. Report 15 May

15 May 2021

715. Chelsea Arnold got vaccinated while breast feeding her one-year-old daughter (click here). Report 11 May

714. Sruthy, a nurse in Dubai contracted covid while pregnant and suffered a miscarriage. Harsha Pushpan contracted Covid at 8 months, recovered and gave birth normally (click here). Report 12 May

713. Catharine Paules got vaccinated in pregnancy and gave birth normally (click here). Report 13 May Vaccine in pregnancy news report

712. An unnamed pregnant woman from Rio de Janeiro reportedly died from a haemorrhagic stroke following the AstraZeneca vaccine (click here). Report 12 May. Vaccine in pregnancy news report Update 4 November. See vaccine source 73 (click here).

711. Erika Loegering was vaccinated twice in pregnancy and gave birth to a healthy son (click here). Despite her husband and older son testing positive she remained negative. Report 14 May Vaccine in pregnancy news report

710. Jessica O’Connell received the COVID-19 vaccine while pregnant (click here). Report 11 May Vaccine in pregnancy news report

709. Dimple Arora Chawla died from Covid-19 at 7 months gestation (click here). Report 14 May

6 May 2021

708. NBC correspondent Jo Ling Kent got vaccinated on 1 April and gave birth in late April (click here). Report 5 May. Vaccine in pregnancy news report

707. Serena Torres contracted Covid-19 while pregnant and required 37 days of ECMO. On 20 Oct 2020, at 32 weeks, she gave birth by Caesarean at Westchester Medical Center in New York State (click here). She recovered. Report 6 May

706. An unnamed woman, who tested positive, gave birth at Teuk Thla Health Center in Sen Sok district, Phnom Penh, on 4 May (click here). Report 6 May

705. Dani Al-Mansouri, from Utah, got her 2nd dose of the Pfizer vaccine at 31 weeks. Yándary Chatwin, got her 1st dose of Moderna at 13 weeks (click here). Report 5 May. Vaccine in pregnancy news report

4 May 2021

704. The unnamed partner of Shyam Sundar tested positive for SARS-CoV-2 and has been isolated after giving birth at Government Rajindra Hospital in Patiala, India (click here). Report 3 May

703. Tanya August-Hanson a member of the Manx (Isle of Man) Legislative Council was vaccinated against covid at 39 weeks gestation (click here). She gave birth last weekend. Report 4 May Vaccine in pregnancy news report

702. This article reports the search for breast milk donors for the babies of two unnamed women who died of Covid-19 (click here). One mother died in Delhi last week, and the other in Lucknow recently. Report 4 May

701. By 4 May 2021, 1,001 SARS-CoV-2 infected mothers had given birth at Nair hospital in Mumbai (click here). They had 1,023 babies, including a set of triplets and 19 pairs of twins. There were 599 normal births and 402 caesareans. Report 4 May

700. An unnamed pregnant woman died from Covid-19 in Varaždin maternity hospital in Croatia (click here). Report 4 May. HT @DanielaDrandic Update 5 May. She was delivered by Caesarean. Baby’s birthweight 2,500g.

699. Mikaely Karoline Souza contracted Covid-19 at 7 months gestation, and died undelivered in the Emergency Care Unit in Sinop, in Matto Grosso, Brazil on 3 May (click here). Report 3 May

698. Maria Laura Prucoli, contracted Covid and was delivered by Caesarean at Saracuruna Hospital, in Duque de Caxias, in Baixa Fluminense, Brazil (click here). She died on 18 April. The baby tested positive but survived. Report 18 April

697. Letícia Aparecida Gomes from Maricá, Brazil, contracted Covid-19 while pregnant and spent a week in ICU. She recovered and the pregnancy is ongoing (click here). Report 4 May

3 May 2021

696. In Alberta, 85 to 95 unnamed pregnant women tested positive within one week (click here). On 30 April three COVID-19 pregnant patients were admitted to one hospital in Calgary. In the same week in Alberta two pregnant patients went to the ICU, and 22 visited the emergency room. Report 1 May

1 May 2021

695. Nair hospital, one of the largest treating pregnant women with Covid-19 in Mumbai has already recorded 26 maternal Covid deaths in 2021, compared with 12 between April and December 2020 (click here). Report 1 May

694. This opinion piece in the South China Morning Post includes the first newspaper report of a maternal death in China; an unnamed “pregnant woman from the rural area in Huanggang, Hubei province, who died of Covid-19 complications after spending more than a week in the intensive care unit at the Wuhan University South Central Hospital” (click here). The case is from early 2020. See also study 383 (click here) which also mentions a maternal death from Wuhan in the supplementary files. Report 1 May

693. The unnamed, five month pregnant, wife of Kolkata journalist, Sujit Nath, contracted Covid-19 on 10 April (click here). She was treated at home with steroids, oxygen saturation monitoring, and home oxygen. She recovered and the pregnancy is ongoing. Report 30 April

692. Christina Jones from South Wales contracted Covid-19 on February 18 (click here). She required nine days ventilation, during which her baby was delivered by Caesarean at 31 weeks, on 2 March. Both recovered. Report 1 May.

691. Laura Hix, from Tulsa, USA, contracted severe Covid-19 while pregnant (click here). She required ventilation and on 30 April, at 28 weeks, was delivered by Caesarean. Report 1 May

690. The unnamed wife of Rafael Córdova from Peru contracted Cobid-19 and gave birth to twins prematurely (click here). Both twins died. Report 29 April.

30 April 2021

689. Shaneen Robinson-Desjarlais from Winnipeg contracted Covid, six days after giving birth (click here). Her baby was also infected. Report 29 April.

29 April 2021

688. Hari Teja, a television actress from India, contracted Covid-19 in late pregnancy (click here). The baby was born by Caesarean on 5th April, not infected, but was isolated from her for a week. Report 29 April

687. Between January and April 2021 at least 433 pregnant, or post-partum women died from covid-19 in Brazil (click here). Report 28 April 2021

686. Four unnamed unvaccinated pregnant women with Covid-19 are currently in intensive care in Beaumont Hospital, Royal Oak, Michigan, USA (click here). In the same article a doctor reports that a small number (possibly only one) pregnant women have died from Covid-19 in Grand Rapids. Report 29 April

28 April 2021 HT Branka Firulovic and Christoph Brezinka for report 683

685. An unnamed woman with Covid-19 delivered twins at a coronavirus community health centre in Chandausi in Sambhal district of Uttar Pradesh on 27 April (click here). Report 28 April

684. Fatma Yıldız contracted Covid-19 in the second trimester of her pregnancy (click here). She was in a coma for 12 days, and required 3 weeks intensive care at Gaziantep University Hospital. The pregnancy is ongoing and she was discharged from hospital on 27 April. Report 27 April

683. An unnamed woman died from Covid-19 on 16 April two days after giving birth by Caesarean at the Clinical Center of Montenegro (KCCG) in Podgorica (click here). The report states that this is the first maternal death among 52 women with Kovid who gave birth in the previous four and a half months in Montenegro. Report 19 April

27 April 2021 HT Branka Firulovic and Christoph Brezinka for reports 675-679

682. Misbah, the wife of Ali Syed, from Saskatchewan, Canada, contracted Covid-19 during her pregnancy (click here). She gave birth safely, but her husband died of Covid-19. Report 26 April

681. Isabel Castillo was vaccinated while pregnant on 6 April, in Santiago, Chile (click here). Report 26 April. Vaccine in pregnancy news report

680. Theresa Potenza contracted Covid-19 in November 2020, at 34 weeks gestation (click here). She was nursed at home and gave birth safely at Ospedale Gemelli in Rome at about 38 weeks. Report 27 April

679. A newborn baby died of Covid-19 age 37 days, at Hagia Sophia hospital in Greece (click here, here or here). Reports 8 March and 20 April

678. An unnamed woman with Covid-19, from Trstenik, gave birth normally in Kraljevo Serbia (click here or here). The baby tested positive and died 10 days later from Corona infection. Report 19 April.

677. A unnamed 24-year-old pregnant woman died on 9 April in the University Clinical Center in Kosovo as a result of covid-19 (click here). The report also states that “Since the beginning of the pandemic, several pregnant women and midwives with kovid 19 have died in Kosovo”. Another unnamed 41 year old woman died in the same clinic on 23 March after giving birth at 31 weeks. Report 9 April

676. An unnamed pregnant woman died from Covid-19 died in Kosovo on 13 April (click here). Report 16 April

675. An unnamed Covid-positive pregnant woman died in Djakovica, Kosovo, on April 21.(click here). Report 21 April.

674. An unnamed woman died from Covid-19 on 26 April shortly after giving birth in Kanpur, India (click here). In Hindi. Report 26 April.

673. An unnamed woman in Kerala died from Covid-19 five days after giving birth (click here). In Malam. Report 27 April

672. An unnamed woman with Covid-19 gave birth safely in Malkangiri district headquarters hospital, in India, on 22 April (click here). Report 27 April

671. Prerna Shrestha got the Pfizer-mRNA vaccine in February when she was pregnant and later gave birth safely (click here). Report 26 April Vaccine in pregnancy news report

25 April 2021

670. Faiza Khan contracted Covid-19 shortly after giving birth in New Delhi (click here). Report 24 April

669. Cara Kirschner Estrada contracted Covid at seven months gestation and was delivered by Caesarean (click here). Her baby is doing well, but she is seriously ill on life support. Report 25 April

24 April 2021

668. Three unnamed pregnant women with Covid-19 are currently being treated in intensive care in Ireland (click here). Report 19 April

667. Yolanda Roberson, from Michigan, who had undergone a liver transplant in 2013 due to autoimmune hepatitis, and was also diabetic, contracted Covid-19 while pregnant on 24 December (click here). She receive monoclonal antibody treatment, and recovered. Report 22 April.

666. Alexa Forbes tested positive after preterm rupture of membranes at 34 weeks (click here). She later developed symptoms. Her baby was not infected. Report 21 April

665. Liz York got vaccinated during pregnancy, and had a Caesarean at 33 weeks (click here). Report 10 April. Vaccine in pregnancy news report

664. Alison Rose tested positive in pregnancy (click here). Report 23 April

22 April 2021

663. Dakota Lee Vest Wright contracted Covid-19 and gave birth by Caesarean at 30 weeks on 20 April (click here). She is currently on ECMO at the University of Alabama at Birmingham hospital. She had decided not to be vaccinated because she was pregnant. Report 21 April Vaccine in pregnancy news report

662. Cara Kirschner-Estrada contracted Covid-19 and gave birth by Caesarean at 28 weeks (click here). She is currently on ECMO at Royal Oak Beaumont hospital in Michigan. Report 22 April

21 April 2021

661. An unnamed woman from Gujarat, India, tested positive for SARS-CoV-2 during pregnancy and gave birth on 1 April (click here). Her baby contracted Covid-19 and died aged 15 days. Report 16 April

660. K Rohini contracted Covid-19 in pregnancy and died on 15 April in a Karimnagar private hospital in India (click here). Report 18 April

659. Dr Stephanie Chen got vaccinated while pregnant (click here). Report 26 March. Vaccine in pregnancy news report

658. Danika Jorgensen-Skakum contracted Covid-19 in December 2020, early in her pregnancy (click here). On 19 April, at 29 weeks gestation, she got a first dose of the Pfizer vaccine. Report 19 April. Vaccine in pregnancy news report

20 April 2021

657. An unnamed woman with severe Covid-19 gave birth normally at a special Covid ICU set up in an art gallery in Kalyan town of Maharashtra’s Thane district in India on 19 April (click here). Mother and baby are recovering. Report 20 April

656. An unnamed woman from Haryana, with Covid-19 gave birth to an infected child at Ayushman Bhav hospital in Haryana, India on 15 April (click here). Report 16 April.

655. A newborn baby from Kragujevac, Bosnia who was infected with Covid-19 died on 19 April, aged 9 days (click here). The mother’s Covid status and health was not reported. Report 19 April. HT Daniela Drandic @DanielaDrandic

18 April 2021

654. Rifat Sultana, a TV journalist in Dhaka, Bangladesh, contracted Covid-19 and was delivered by Caesarean on 15 April (click here). She died the following day. Report 17 April.

17 April 2021

653. An unnamed woman with Covid-19 was delivered by Caesarean at Ghai Hospital in Jalandhar, India on 14 April (click here). Report 17 April

652. An unnamed woman in Canada contracted Covid-19 and had to be delivered by Caesarean (click here). Another unnamed pregnant woman is currently on a ventilator in a Toronto ICU. Report 16 April.

16 April 2021

651. Six stillbirths and one miscarriage caused by Covid-19 in Ireland (click here). May include four from news report 603. Report 13 April.

650. A pregnant woman identified only as Megan contracted severe covid-19 towards the end of her pregnancy (click here). She required treatment in ICU but recovered. There are currently five pregnant women with Covid in one Toronto ICU and two in one McMaster ICU. Report 14 April

649. Two pregnant women in Hong Kong who had received BioNTech vaccine suffer miscarriages (click here). Report 14 April. Vaccine in pregnancy news report

15 April 2021 – two reports of maternal death from Bulgaria and five from Romania added. H/T Dr Branka Firulovic and Dr Christoph Brezinka

648. An unnamed pregnant woman died of Covid-19 at 20 weeks gestation, at Bega Maternity Hospital in Timisoara in March (click here). 14 other pregnant women infected with Covid-19, were in the same hospital, of whom three were in intensive care. Report 31 March

647. An unnamed 32-year old nurse from Buzäu with Covid-19 was delivered by Caesarean at Bucur Maternity Hospital in Bucarest (click here). She died a few days later. Report 5 January

646. Mirela Paiu contracted Covid-19 and was delivered by Caesarean at 35 weeks at Galati Hospital in Romania (click here) She died two days later. Report 14 December

645. An unnamed woman with Covid was delivered by caesarean at Timisioara hospital at 6 months gestation. The baby survived but the mother died two weeks later (click here). Report 9 December

644. An unnamed 34-year-old pregnant woman, with Covid, died at the “Bega” Maternity Hospital in Timişoara, Romania in March (click here). There are two other pregnant women with Covid in the same hospital. Report 31 March

643. A 32-years old pregnant woman in Bulgaria died of Covid on 5 March (click here). Report 5 March

642. An unnamed pregnant woman with coronavirus died at Blagoevgrad hospital in Bulgaria on 13 March (click here). There is another pregnant woman recovering from Covid in the same hospital. Report 13 March

13 April 2021

641. Liz Essley Whyte, a journalist, received the Pfizer vaccine in April while pregnant (click here). Report 12 April. Vaccine in pregnancy news report

640. Actor Sophie Rundle, BBC dramas Peaky Blinders and Gentleman Jack, contracted Covid-19 in December 2020. She recovered and gave birth over the Easter weekend (click here). Report 12 April

639. Liz Clim contracted Covid-19 while pregnant, and gave birth by Caesarean at 28 weeks at Elena Doamna Maternity Hospital in Romania (click here). Following the birth she was transferred to the Emergency Clinical Hospital “Saint Spiridon” where she died. Her baby tested negative but also died. Report 9 April.

638. Three unnamed women with Covid-19 gave birth naturally in a new unit at Makarios hospital in Cyprus (click here). Previously the hospital had insisted that all affected women had to deliver by Caesarean, due to problems with the hospital’s ventilation system. Report 12 April

9 April 2021

637. Hundreds of pregnant women were vaccinated against Covid-19 at a special clinic at UPMC Magee-Womens Hospital in Pittsburg, on 8 April (click here). Meg Graham and Breawna Taylor were named in the report. Report 9 April. Vaccine in pregnancy news report

636. Asha Vanshiv contracted Covid-19 and gave birth to twins by Caesarean on 5 April, at YCM Hospital in Pune, India (click here). She died the following day. The twins are doing fine. Report 9 April

635. Rhiannon Lane contracted Covid-19 and gave birth by Caesarean on March 21 at Texoma Medical Center in Texas (click here). Shortly afterwards her health deteriorated, she required ventilation and spent 18 days in ITU. She is recovering. report 9 April

7 April 2021

634. Charlene Jones contracted Covid-19 during her pregnancy and gave birth by Caesarean on 23rd December (click here). Two days post natally she required intubation and ventilation. She recovered. Report 7 April

633. An unnamed woman with severe Covid-19 gave birth at 29 weeks while intubated and ventillted at Attikon Hospital in Athens, Greece (click here). The date of the delivery is not reported. Report 7 April.

6 April 2021

632. Zeynep Aslı Kaplan received the CoronaVac vaccine (also known as Sinovac COVID-19) in the 29th and 33rd weeks of her pregnancy, and gave birth at 38 weeks (click here). Report 6 April. Vaccine in pregnancy news report

2 April 2021

631. Three unnamed women at Can Misses hospital in Ibiza have been vaccinated in pregnancy and one has given birth to a baby with antibodies (click here). Report 2nd April Vaccine in pregnancy news report

30 March 2021

631. Mbali Mbatha contracted Covid-19 and was delivered by caesarean at 30 weeks on 1 December at Netcare Milpark Hospital in Johannesburg (click here). She was treated with ventilation, ECMO and eventually a lung transplant. She and the baby recovered. Report 30 March.

630. Yumi Palmer contracted Covid-19 in March 2020, just before she gave birth (click here). Report 30 March 2021.

28 March 2021

629. An unnamed 21-year-old Jordanian women died of Covid-19, on 23 March, eight days after giving birth at Prince Hamzah hospital, Ru’a Nsour (click here). Report 28 March.

628. Ann-Marie Williams, from Cornwall, who requires parenteral feeding for a mystery illness, gave birth to twins in January 2021 and contracted Covid-19 soon afterwards (click here). She recovered. Report 27 March.

27 March 2021 (including update on reports 289 and 601)

627. Haley Saunders got the Moderna vaccine, with her second dose at 9 months gestation (click here). She gave birth Feb. 24 at Southwest Memorial Hospital in Colorado. Report 23 March. Vaccine in pregnancy news report

626. Dr Maggie Burke, from Bethesda, Maryland, received the Pfizer vaccine at 27 and 30 weeks gestation, and gave birth on 13 March (click here). The baby was healthy and had antibodies. Report 25 March. Vaccine in pregnancy news report

21 March 2021

625. Asarwa Civil Hospital, Ahmedebad, India has cared for 200 births to Covid-19 positive women (click here). They included Radihika Parihar, Hiral Shah, Ritu Yadav, and Asha Patel, all of whom delivered healthy babies. Report 21 March

624.  Louise Tranham from Margate contracted Covid-19 in November at 26 weeks gestation (click here). Her baby died in utero at 27 weeks and 5 days. Report 21 March.

623. Kim Murray, wife of tennis player Andy, tested positive late in her fourth pregnancy (click here). She gave birth normally in early March, and the baby is healthy. Report 21 March.

18 March 2021 (including update on report 548)

622. Nisa Celik received the Astra Zeneca vaccine at 11 weeks gestation (click here). She had short term side effects. The pregnancy is ongoing. Report 17 March. Vaccine in pregnancy news report

621. By October 31, 2020, about 1,835 Covid-positive pregnant women had given birth in the state of Kerala, India (click here). 245 of their babies had tested Covid positive. Report 18 March

620. Jennifer Pinedo contracted Covid-19 at 36 months [sic] gestation (click here). Note – presumably 36 weeks. She recovered and gave birth to a healthy daughter. Erin Arnst, from Fowlerville, got the vaccine at six months. Her pregnancy is ongoing. Report 18 March. Vaccine in pregnancy news report

17 March 2021

619. About 20% of women presenting in labour to Port Moresby General Hospital in Papua New Guinea have symptoms of Covid-19 (click here). Of them, about one-third (four to five women a day) test positive. Report 16 March

16 March 2021

618. Michelle Melton, got the Pfizer-BioNTech vaccine at 35 weeks gestation at Skippack Pharmacy in Schwenksville (click here). Report 16 March Vaccine in pregnancy news report

617. Shuruq Jubran from Jisr az-Zarqa in Israel contracted Covid-19 and was treated at Hadera’s Hillel Yaffe Medical Center (click here). She died on 15 March, three weeks after giving birth. Her sister, Amna Kahwaji, had died 10 days earlier, a week after giving birth, also from Covid-19. Report 16 March.

616. Since the beginning of February, three unnamed pregnant women aged 22, 27, and 32 years have died from Covid-19 in Tirana, Albania (click here). Another three pregnant women, one of whom is critically ill and intubated, are currently hospitalized with the disease. Report 15 March.

615. Nayeli Rodulfo-Zayas, a doctor from San Antonio, treating Covid-19 patients had the Pfizer Covid-19 vaccination in December, the 2nd dose in January, and gave birth to a healthy boy on 28 January (click here). Report 15 March. Vaccine in pregnancy news report

614. Carrie-Anne Osborne, from Hartlepool, UK, contracted Covid-19 at 33 weeks and gave birth on 29 December (click here). She spent four weeks in ITU but recovered. Report 16 March.

15 March 2021

613. Nair Hospital, Mumbai has cared for over 1,100 Covid-positive expectant mothers, of whom 764 have given birth and 45 babies have been infected (click here). The birth of Tanushri Bhanage is described in detail. Report 15 March

612. Alexia Khammanivong contracted Covid-19, at 30 weeks, required ventilation and ECMO, and gave birth by Caesarean (click here). Her baby died of complications of prematurity, but she recovered. Report 15 March.

14 March 2021

611. Arpana Dalvi, Prachi Kunal Salgia, and Ritika Khatri, all contracted Covid-19 while pregnant, and gave birth in 2020, in India (click here). Report 14 March

610. Three unnamed women with Covid-19 who required treatment with ECMO in Rabin Medical Center in Petah Tikvah are recovering (click here). The article also states that there are 41 pregnant or recently pregnant women hospitalised with Covid-19 in Israel. Report 13 March

13 March 2021

609. Yvett Camacho from Fontana in California, contracted Covid-19 at 30 weeks (click here). She was delivered by Caesarean and, from 21 to 31 January, was treated with ECMO at Cedars-Sinai Medical Center in Los Angeles. Mother and baby recovered. Report 12 March.

11 March 2021

608. Mel Wilson, from Harrisburg, Pennsylvania, got vaccinated at 28 weeks (click here). She is due in March. Report 11 March. Vaccine in pregnancy news report

607. Maidi Martínez from Cuba contracted severe Covid-19 and gave birth by Caesarean at 35 weeks at Manuel Fajardo Military Hospital (click here). Mother and baby recovered. Report 10 March

7 March 2021

606. Rachael Mutch tested positive for SARS-CoV-2 and gave birth at term at Ipswich Hospital on Feb 12 (click here). Report 6 March

6 March 2021

605. Mary Ann Brussels contracted Covid-19 at 34 weeks in April 2020 (click here). She gave birth by Caesarean at Long Island Jewish Medical Center, and later required ventilation. Both mother and baby recovered. Report 5 March

604. An unnamed women with Covid-19 gave birth on 6 March by Caesarean section at the General Hospital of Corfu (click here). Mother and baby are in good health. Report 6 March

4 March 2021

603. Four unnamed women with mild or moderate Covid-19 in the Republic of Ireland experienced a stillbirth in January and February 2021 (click here). Report 4 March.

602. Allison Goldfarb tested positive for Covid in late pregnancy and in January 2021 gave birth in a car on the way to hospital in New York (click here). Report 3 March.

601. Victoria Gallardo from Cypress, Texas, contracted Covid-19 about 11 days after giving birth (click here). She is now in a coma in an ITU in Texas. Report 4 March. Update 27 March (click here). She died on 16 March.

2 March 2021

600. An unnamed women with Covid-19, who had recently given birth, and was being cared for in the Covid care hospital at Lal Chowk, in Kalyan, near Mumbai, was allegedly sexually assaulted on 1st March (click here). Report 2 March

599. Witney Carson, a celebrity dancer, had Covid-19 when her son was born by 2nd stage Caesarean in January (click here). Report 1 March.

598. Ellie Wright from Walsall contracted Covid-19 at 30 weeks and gave birth by Caesarean on 12 January (click here). She required three weeks ventilation and remains in hospital. The baby has gone home. Report 1 March.

28 Feb 2021

597. After mentioning the woman in report 588, this report states that 50 pregnant are currently hospitalised in Israel with Covid-19 (click here). Report 27 February

596. An unnamed woman who had contracted Covid-19 at 25 weeks, experienced a stillbirth at 36 weeks (click here). She was cared for at Meir Medical Center, Kfar Saba, Israel. Report 27 February

27 Feb 2021

595. Joanna Jimenez contracted Covid-19 and gave birth on Feb. 13 (click here). She died a few days later. Report 27 February.

594. An unnamed pregnant woman from Bhopal, India, told CNN she had received the first injection Covaxin before being turned away for the second dose due to her pregnancy (click here). Report 26 February Vaccine in pregnancy news report

593. MaElena Barcenas from  Detroit contracted Covid-19 in March 2020 at 30 weeks and required delivery by Caesarean and 33 days ventilation.  Russell Powell, from Charleston, South Carolina, contracted Covid-19 at 30 weeks and went into preterm labour at 33 weeks. (Click here for their stories.) The story of report 293 is included. Report 26 February

25 Feb 2021

592. An unnamed woman had severe Covid-19 at 32 weeks, and was delivered by Caesarean in January (click here). Following ECMO treatment she is now in a coma in Leicester Royal Infirmary, her chance of survival is slim, and a judge has ruled that that her doctors can lawfully stop providing life-support treatment. Report 21 February.

21 Feb 2021

591. An unnamed woman with Covid-19 gave birth in an ambulance on her way to hospital in the northern Malappuram district of Kerala (click here). Mother and baby are doing well. This is said to be the third report of Covid positive women giving birth in an ambulance in Kerala. Report 21 February

590. Olivia Buxton, from West London, tested positive for Covid-19 at 36 weeks gestation (click here). She gave birth normally on Jan 24 at 39 weeks. Her baby Jude was healthy.  Report 21 February.

589. Catherine Mezzacappa, a doctor, got vaccinated while pregnant (click here). She registered with the CDC V-safe phone app. Report 19 February. Vaccine in pregnancy news report

588. Osnat Ben-Shitrit from Jerusalem contracted Covid-19 at 30 weeks gestation and died (click here). Her baby delivered by Caesarean died too. Report 21 February. She had not been vaccinated (click here). Update 23 February Vaccine in pregnancy news report

20 Feb 2021

587. Ashley Wadley, from Oregon, contracted mild Covid-19 at 31 weeks gestation (click here). She stayed home. Her baby was born via Caesaren 4 days later on Jan 15. He tested positive and died on 17 Jan. Report 19 February

17 Feb 2021

586. Dr. Jane Martin, got her COVID-19 vaccine while pregnant with her third child (click here). The baby was born healthy. Report 17 February. Vaccine in pregnancy news report

585. Olivia Hall had symptoms of Covid-19 early in the pandemic but was not tested. She gave birth by Caesarean in Southmead hospital, Bristol on 25 March (click here). Report 17 February

584. Three unnamed women with Covid-19 have given birth to stillborn babies in Assuta Hospital in Ashdod, Isreal, according to the head of infectious diseases there, Dr Tal Brosh (click here). Report 16 February

16 Feb 2021

583. Emma Bullen, from Tiverton, contracted Covid-19 at 39 weeks and gave birth by Caesarean at Royal Devon and Exeter Hospital (click here). Both recovered. Report 15 February

15 Feb 2021

582. Twelve pregnant women are reportedly critically ill with Covid-19 in Israel (click here). Details were given for two. One on a ventilator in Kaplan hospital in Rehovot, and another seriously ill at 13 weeks gestation in an unnamed hospital. Report 15 February.

581. Chaya Mehlman, Joelle Harari-Chadow, and another 250 pregnant women received Covid-19 vaccination at the Center for Health Education, Medicine and Dentistry, in Lakewood, New Jersey, between 12 and 14 February (click here). Report 15 February. Vaccine in pregnancy news report

13 Feb 2021

580. Bridget Klingenberg, from Covenant, contracted COVID-19 at 27 weeks gestation (click here). She is currently in ICU at the University of Michigan and the pregnancy is ongoing. Report 12 February.

579. Bat Sheva Baruch, from Jerusalem, Israel, contracted COVID-19 at 31 weeks gestation (click here). She required treatment in ICU and support with breathing, but the pregnancy continued and is ongoing. Report 12 February.

11 Feb 2021

578. Zarina Rose from Las Vegas contracted Covid-19 at 32 weeks gestation (click here). Labour was induced but she died shortly after birth. The baby survived. Report 11 February

9 Feb 2021

577. Two unnamed pregnant women are seriously ill with Covid-19 at Hillel Yaffe Medical Center, Israel (click here). One was delivered at 34 weeks and one at 37 weeks, both by Caesarean. Report 7 February.

576. Rose Jimmichen from Scunthorpe, UK, contracted severe Covid-19 in pregnancy (click here). She was delivered by Caesarean at 29 weeks. Report 2 February

575. Tori Howell from the Forest of Dean in Gloucestershire, UK, contracted Covid-19 at 22 weeks (click here). The pregnancy is ongoing. Report 5 February.

574. An unnamed 30 year old resident of Lakewod, New Jersey, contracted Covid-19 while pregnant (click here). Report 8 February.

7 Feb 2021

573. Rachel McCartney, from Aldershot, who was pregnant with twins, had two inconclusive Covid-19 tests and was induced at 34 weeks at Frimley Park Hospital, Surrey (click here). Report 7 February.

6 Feb 2021

572. Veronica Bernal from Arizona died of Covid-19 shortly after giving birth to twins (click here for 6 Feb google search on which she appears). No primary reports accessible in Europe due to data protection issues. Report 6 February. 10 Feb update. Click here for a report available in Europe.

571. Maggie Romano got vaccinated at 15 weeks gestation and Sarah Scherschel at 31 weeks (click here). Report 5 February. Vaccine in pregnancy news report

570. Paula Zion contracted severe Covid-19 at 17 weeks gestation, and required ventilation. She recovered and gave birth to a healthy boy on 4 February at the Royal Bolton Hospital (click here). Report 5 February.

569. Becky Regan, from Blyth, Northumberland died of Covid-19 on Feb 1st, shortly after giving birth by Caesarean at 31 weeks gestation (click here). Report 5 February

4 Feb 2021

568. Anthony Fauci says that about 10,000 pregnant women have received Covid-19 vaccinations in the USA and no “red flags” have been noted (click here). Report 1 February. Vaccine in pregnancy news report

3 Feb 2021

567. Christelle Berrington from Durban, South Africa, contracted Covid-19 at 35 weeks (click here). The baby delivered and she recovered. Report 25 January

1 Feb 2021

566. Maria Murillo, from Oklahoma City, contracted Covid-19 in July, at 25 weeks gestation (click here). The baby was delivered by Caesarean, and the mother required ventilation and a month in ITU. Both survived, although the baby remains in neonatal intensive care. Report 1 February. Update 11 July. The baby is still in intensive care (click here). It appears she cannot be weaned off the ventilator. Report 11 July

565. Anischa Morris, from Cape Town, contracted Covid-19 at 34 weeks in early December (click here). Her baby was delivered by Caesarean section at Groote Schuur Hospital, and went home on Dec 23rd. But Anischa’s condition deteriorated, and she died on 14 January. Report 1 February

564. Kelsey Townsend, from Madison, Wisconsin, contracted Covid-19 in October (click here). She gave birth on Nov 4th and required prolonged ventilation and ECMO at UW Health, University Hospital Wisconsin. At one point she was considered for a lung transplant, but this was not necessary. She left ICU mid January, and went home on 27 January. Report 1 February

563. Samantha Spicer, from Rushden, Northamptonshire, contracted Covid-19 at 12 weeks gestation (click here). The pregnancy is ongoing. Report 1 February.

562. Olympic gymnast Shawn Johnson, who is currently pregnant with her second baby, tested positive for COVID-19 early in her second pregnancy (click here). The baby is due in the summer. Report 1 February

30 Jan 2021

561. Kailtin Bolan a registered nurse at Fresenius, New York, got vaccinated against Covid-19 while pregnant (click here). Report 29 January. Vaccine in pregnancy news report

560. An unnamed pregnant woman is pictured receiving the Pfizer-BioNtech Covid-19 vaccine in Tel Aviv on January 23, 2021 (click here). Report 30 January. Vaccine in pregnancy news report

559. Farheen Raza, a radio personality from Flower Mound, Texas, contracted COVID-19 in April 2020. but did not fully recover (click here). In September she conceived and has continued to have post Covid symptoms through the first four months of her pregnancy. Report 30 January.

28 Jan 2021

558. Eva Gicain, from Basildon, contracted Covid-19 at 34 weeks gestation in late October (click here). She required ventilation, and ECMO for three weeks, but recovered. Report 28 January

557. Natalie Keller from Oklahoma contracted Covid-19 and was delivered by Caesarean (click here). Report 26 January

556. Reality TV star Lauren Goodger contracted Covid-19 in October, early in her pregnancy (click here). The pregnancy is continuing and she is due to give birth in July. Report 26 January

555. Visibly pregnant 34-year-old Narkis received her coronavirus vaccine in Tel Aviv, January 21, 2021 (click here). Report 27 January. Vaccine in pregnancy news report

554. Elsa Larkins contracted Covid-19 and required ventilation and preterm caesarean birth at Kingston Hospital, London on 5 Jan (click here). She remains in intensive care. Report 22 January. Update 1 February, mother & baby recovered (click here).

25 Jan 2021

553. Mandy Nguyen contracted Covid-19 at 32 weeks gestation and gave birth on 6 April 2020 by Caesarean section at the Royal London Hospital (click here). She required 3 weeks of ECMO support, but survived. Report 25 January

24 Jan 2021

552. Pregnant Houston city council member, Abbie Kamin received the Covid-19 vaccine recently (click here). The article also reports Stephanie Humbert, division manager of the health department’s nurse family partnership program as saying that about 17 pregnant women have also received the vaccine. Report 24 January. Vaccine in pregnancy news report

551. An unnamed 28-year-old woman from Dhamtari district gave birth to triplets in the All India Institute of Medical Sciences (AIIMS) Raipur, Chhattisgarh, India on 18 october 2020 (click here). Report 30 October.

23 Jan 2021

550. Ashley Bennett from South Carolina, died of Covid-19 on Jan 8, a week after giving birth by Caesarean to her 10th child (click here). Report 22 January.

549. Courtney Sewell from Oldham contracted coronavirus at 35 weeks and gave birth at St Mary’s Manchester (click here). Mother and baby are well. Report 23 January

20 Jan 2021

548. Jackie Dennis from Michigan contracted Covid-19 in November, and birth was induced on November 27th (click here). She was placed on a ventilator at Henry Ford Wyandotte Hospital on Dec. 5th and later transferred to another hospital where she required ECMO for a month. On 16 January she received a lung transplant. Report 19 January. Update 18 March (click here). She has recovered and been discharged home without oxygen. Update report 17 March.

547. Sameera Khan contracted Covid-19 in early January and required ventilation, and delivery by Caesarean, at the Royal London Hospital (click here). At the time of the report, she remained seriously ill. The baby was stable. Report 20 January. Update (click here). She required two months ventilation but survived, although she still requires a wheelchair. Her baby also survived. Update 18 August 2021

546. Leslie Shaw, from California, contracted Covid-19 in December 2020, and was delivered by Caesarean (click here). She died two weeks after birth. The baby survived. Report 18 January.

19 Jan 2021

545. Fatima Mohammed, from Bahrain, was infected early in her pregnancy (click here). No further details. Report 19 January

544. 750 pregnant women with Covid-19 have been cared for at the Institute of Obstetrics and Gynaecology and Government Hospital for Women and Children, Egmore, Chennai, India (click here). Report 19 January.

543. Katharine McMurray, from Oro Valley in Tucson, Arizona, contracted Covid-19 at the end of June 2020 and was delivered by Caesarean at 31 weeks (click here). Mother and baby survived. Report 18 January.

542. An unnamed woman with Covid-19, from Pazardzhik in Bulgaria, gave birth by Caesarean on 18 Jan (click here). Report 19 January

541. There are currently ten pregnant women hospitalised with severe Covid-19 in Israel (click here). They include four in Mayanei HaYeshua Medical Center in Bnei Brak, and one transferred from Laniado hospital in Netanya to Beilinson hospital in Petah Tikvah and ventilated. The Laniado Hospital is also treating another woman with COVID-19 who was placed on a ventilator after delivery (for details of this latter case click here). On 17 Jan a baby delivered to a mother with COVID-19 died at the Hadassah Medical Center in Jerusalem. Report 19 January. Some of the women are named here. Report 19 January

17 Jan 2021

540. Heli Prizant contracted Covid-19 in the third trimester (click here). She gave birth by Caesarean at Sheba Medical Centre in Israel and her baby was isolated from her. Both recovered. Report 16 January

14 Jan 2021

539. Taylor Kern from Mt. Washington, Kentucky, contracted Covid-19 at nine months gestation (click here). She required delivery by Caesarean, ventilation and 9 days treatment with ECMO. She recovered. Report 14 January

538. Nosipho Nkantini, from Eerste River in Cape Town, South Africa, contracted Covid-19 in early December (click here). She required ventilation and her baby was delivered by Caesarean on 17 December at 25 weeks. Both survived. Report 14 January.

537. Sam Hicks, from Bristol, UK, contracted Covid-19 in November and gave birth on 11 January (click here). Report 14 January.

536. Ashleigh Shirajudin, from Rhos-on-Sea, Wales, contracted Covid-19 at the end of her pregnancy with triplets (click here). She gave birth by Caesarean and all three babies were fine. Report 14 January.

535. Three doctors, Elizabeth Espinal at 20 weeks, Jackie Parchem gestation not reported, and Elaina Preston at 11-weeks received the Covid-19 vaccine (type not specified) while pregnant (click here). Report 13 January. Vaccine in pregnancy news report

534. Dr Tsion Firew contracted Covid-19 early in her pregnancy and recovered (click here).  On 24 December, at 27 weeks gestation she received the first dose of either the BioNTech/Pfizer or Moderna vaccine. 2nd dose 13 January. Report 13 January Vaccine in pregnancy news report

12 Jan 2021

533. Up to 8 January, 104 pregnant women had contracted Covid-19 in Cuba but none died (click here). There were also 17 postpartum cases, and two associated with ectopic pregnancy. The first report from Cuba. Source the Ministry of Public Health (MINSAP). Report 11 January.

532. Joy-Anna Duggar, a US TV personality, contracted Covid-19 at some stage in her pregnancy and gave birth to a healthy baby in August 2020 (click here). Report 11 January.

531. Of 192 births to Covid positive women at Sir Jamshedji Jeejeebhoy Hospital in Mumbai, India, no mothers have died and no babies tested positive (click here). This hospital has not previously reported cases. Report 12 Jan.

11 Jan 2021

530.  Veronica Guevara-Giron from Southland, Los Angeles, contracted Covid-19 at 34-weeks gestation (click here).  Despite ventilation, she died on 7 January. Her baby was delivered by Casearan at 35 weeks, and is OK. Report 10 January.

529. Steph Almond, from Manchester, tested positive for SARS-CoV-2 in labour (click here). She gave birth normally.  Report 10 June.

528. Revathi Pentapati was pregnant with twins when she contracted Covid-19 at about 36 weeks gestation (click here). She required ventilation and the twins were delivered by Caesarean at Milton Keynes Hospital in UK. Mother and babies are now recovering. She must be the previously unnamed woman in report 522. Report 11 January.

527. Aquarius Bunch contracted Covid-19 and was treated with ECMO at the University of Iowa hospitals in May 2020 (click here). This video clip (click here) shows her mobilising on ECMO. She recovered and was discharged on May 10th with the pregnancy ongoing. She gave birth to a healthy baby on 12 Aug. Report 14 August.

9 Jan 2021

526. María de Jesús Maroquín Hernández, from Ometepec, Guerrero, Mexico, contracted Covid-19 at 36 weeks gestation and was treated Acapulco General Hospital (click here). She had a girl and both recovered. The same report also describes Grecia Denise Espinosa who tested positive for the coronavirus at the National Institute for Perinatology in Mexico City, and gave birth to twins by cesarean. Again mother and babies recovered. Report 22 December.

525. Jennifer Chacon tested positive for SARS-CoV-2 on admission in labour early in January (click here). She gave birth at Dignity Health St. Bernadine Medical Center, San Bernadino, California. Mother and baby are doing well. Report 8 January

524. Tiere Scott White, from Omaha, contracted Covid-19 in late pregnancy in October (click here). She spent 30 days anaesthetised, and presumably ventilated. Her baby was delivered at 32 weeks. Both recovered. Report 8 January

523. Gemma Robinson from Hereford, UK, tested positive for SARS-CoV-2 in labour on 20 December (click here). Her and the baby were fine. Report 9 January.

522. An unnamed 36 year old woman with twins contracted severe Covid-19 and required ventilation and delivery by Ceasarean at Milton Keynes Hospital in early January (click here). The same report describes Daniyal Rizvi, who contracted Covid-19 and required critical care, but not ventilation at 13 weeks gestation. Her pregnancy is ongoing. Report 8 January

7 Jan 2021

521. Laura Eames, from Hull, East Yorkshire, was asymptomatic but tested positive for SARS-CoV-2 the day before her elective Caesarean (click here). Report 30 December.

520. Asley Gomez, from Van Nuys, Los Angeles, contracted Covid-19 and was delivered by Caesarean at Kaiser Woodland Hills hospital in December, but died soon afterwards (click here). Report 7 Jan

6 Jan 2021

319. Kaylee Gabak contracted Covid-19 on Christmas day and gave birth the next (click here). On 29 December she required ventilation and ECMO. Both are ongoing. Report 5 January.

318. Helen McEntee, Justice minister in the Republic of Ireland, who had announced her pregnancy on December 5th, tested positive for SARS-CoV-2 in early January (click here). Her pregnancy is ongoing. Report 6 January

317. Rachel Arfin contracted Covid-19 at 35 weeks and was was admitted to the ICU in University College London (click here). Her pregnancy is ongoing. Two other unnamed pregnant women are in the ICU in the same hospital. Report 6 January

5 Jan 2021

316. Safna, wife of Zulfikar Ali, from Thrissur, Kerala, India, contracted Covid-19 at term and gave birth by caesarean (click here). She recovered and the baby was not infected. Report 5 January.

315. Mackenzie Eagle Road, from McAlester, Oklahoma, USA, contracted Covid-19 at term (click here). She gave birth normally and recovered. The baby tested negative. Report 5 January.

314. JoEllen Engelbart, a lawyer from Missouri, USA, contracted Covid-19 and gave birth 3 months prematurely on 29th Dec (click here). She died four days later. The baby survived. Report 4 Janurary.

4 Jan 2021

313. Silatik Qavvik, from Sanikiluaq, Canada, contracted Covid-19 while pregnant and gave birth by Caesarean in November (click here). She died about a month later of complications of the disease. Her baby “is fine”. Report 3 January.

312. Beth Olliver from Barrow-in-Furness, UK, contracted Covid-19 at 16 weeks gestation and gave birth by Caesarean at 24 weeks due to obstetric complications, preterm rupture of membranes (click here). She and her premature baby survived. Report 4 January.

3 Jan 2020

311. Jennifer McWilliams, who had recently tested positive for SARS-CoV-2 gave birth at the National Maternity Hospital in Dublin, Ireland, on 1 January (click here). Report 2 Jan.

310. Iqra, wife of Ali Muhammad, who had Covid-19, gave birth by Caesarean in Hyderabad, India, on 2 January (click here). Report 3 Jan.

309. Emi Maganja from Croatia, contracted severe Covid-19 and gave birth on 14 December (click here). The baby survived but she died on 31st December. Report 1 Jan.

1 Jan 2020

308. An unnamed pregnant nurse in Tulsa, Oklahoma, recovered from Covid and her pregnancy was continuing (click here). Report 31 December.

307. Sukanya Gawda, from Mumbai, India, was asymptomatic, but tested positive for SARS-CoV-2 at term, and gave birth to a healthy boy in Nair hospital on May 12 (click here). Report 1 January.

306. An unnamed pregnant women with Covid-19 is being cared for in intensive care at London’s Whittington Hospital (click here). Report 31 December.

305. Keira Sanded, from Newhaven, East Sussex, UK, contracted Covid-19 at 21 weeks gestation (click here). The pregnancy is ongoing. Report 31 December.

304. Susie Espinoza, from Memphis, USA, contracted Covid-19 at 27 weeks gestation in May 2020, and gave birth by Caesarean while on a ventilator (click here or here). She and the baby recovered. Report 31 December.

303. Hilda Cruz Perez from Ohio, USA, contracted Covid-19 at and gave birth to a healthy boy by Caesarean (click here). After the birth her condition deteriorated, and she is currently ventilated and being treated with ECMO at Promedica Toledo hospital. Report 28 December.

31 December

302. Mariam Muhammad (a pseudonym), from Garowe, Puntland, Somalia contracted Covid-19 at eight-months gestation at the beginning of November 2020 (click here). She recovered and gave birth at term. The report describes ten other SARS-CoV-2 positive pregnant or postnatal women, and 20 suspected cases. Report 30 December.

301. Mehpara Navqi, from Bradford, UK, contracted Covid-19 at the start of October, at 7 months gestation (click here). She required nine days ventilation, and her baby was delivered prematurely by Caesarean. Both survived. Report 31 December.

28 December

300. Cindy Zepeda from California, contracted Covid-19 while pregnant and died in July (click here). The baby also died. Report 28 December.

299. Grace Victory, a UK social media personality, contracted Covid-19, as a result of which her baby had to be delivered early (click here). Her condition deteriorated and at the time of writing she had been placed in an induced coma. Report 28 December.

27 December

298. Sasha Jackson, from Birmingham, Alabama, contracted Covid-19 in July and gave birth prematurely (click here). Both mother and baby survived. Report 25 December.

297. Monique Jones, from Missouri USA, contracted Covid-19 at 5 months gestation (click here). She required prolonged ventilation, and her baby was born prematurely, but both survived. Report 27 December.

24 December

296. This newspaper report (in French) includes mention of 15 ectopic pregnancies & 34 maternal deaths in women with Covid-19, which have not previously been reported (click here). The maternal deaths are from the Indian “PregCovid Registry”. Denominator not stated, but rate reported as 1.1%. Report 21 December

23 December

295. Sara Roby, from Louisville, Kentucky, tested positive for SARS-CoV-2 during labour (click here). She was asymptomatic and gave birth normally. Her baby tested positive. Although reportedly also asymptomatic, the baby was retained in hospital. Report 23 December.

294. Alexandra Abrill, from Canada, contracted Covid-19 in December, near term (click here). She gave birth soon after, and the baby tested negative. Report 19 December

293. Vanessa Gonzalez, from Whittier in California, contracted Covid-19 in November, and gave birth shortly after (click here). The baby survived, but her condition deterioriated and she died on December 14. Report 23 December.

292. Cecilia Duran, a midwife in New York, contracted Covid-19 in March at 10 weeks gestation (click here). She recovered and had a healthy baby. Report 23 December.

291b. Tori Wiley, a nurse from Georgia, USA, contracted Covid-19 early in pregnancy, recovered, and gave birth normally at term to a healthy boy (click here). Report 23 December.

22 December

291a. Vasilisa Frolova, Ukrainian TV and radio host, tested positive for SARS-CoV-2 late in her pregnancy (click here). Report 22 December.

14 December

290. Nicole Keane, from Lexington Kentucky, tested negative for SARS-CoV-2 when her husband had symptoms and tested positive (click here). She was due in December, but on October 26, her baby was delivered by emergency Caesarean. The baby suffered brain damage. Her husband died of Covid-19 a short time after the birth. Report 14 December.

289. Princess Sophia of Sweden is pregnant and due in late March/early April (click here). It had previously been reported that she tested positive for SARS-CoV-2 on 24 November (click here). This would suggest she was about 20 weeks gestation when she tested positive. Report 14 December. Update 5 Jan. This report (click here) confirms that the had SARS-CoV-2 during the pregnancy and has recovered. Update 27 March (click here). She gave birth to a healthy baby on 26 March.

288. Kate Glaser from Buffalo, New York, and Erica Evert, from northern Virginia both contracted Covid-19 in late pregnancy (click here). Glaser’s route of delivery was not reported. Evert had a Caesarean. Both babies tested negative. Report 14 December

13 December

287. Dalia Gabriela Sosa Atondo, an obstetrician in Culiacán, Mexico contracted Covid-19 at 30 weeks gestation (click here). The baby survived, but she died on 21 August. Report 22 August.

10 December

286. Tawauna Averette from Ohio contracted Covid-19, and was delivered by Caesarean, but died on 14 November (click here). The baby was healthy. Report 10 December.

9 December

285. A woman named only as D, age 22, contracted Covid-19 and gave birth normally at FL Tobing Sibolga Hospital in North Sumatra on 11 November (click here). Report 15 November.

284. Eva Ahmed, age 28, from Wednesbury, in the West Midlands, UK, contracted Covid-19 and gave birth by Caesarean, on November 16 at 28 weeks (click here). After the birth she required ventilation but recovered. Report 2 December.

283. Svetlana Sorochinskaya, age 36, from St Petersburg, Russia, contracted Covid-19 and required ventilation (click here). She gave birth at 34 weeks and died shortly afterwards. Report 1st December.

282. Jasmine Logan from Detroit was pregnant with twins when she contracted Covid-19 (click here). Labour was induced, but her condition deteriorated, and she required treatment with ECMO at Detroit Medical Center. She recovered, but at the time of writing is still in hospital. Report 8 December.

281. None of the 62 pregnant women from Pune, India, who came into contact between April 6 to 8th with an ultrasonographer who had later tested positive, had shown symptoms by April 16th (click here). Report 16 April.

280. According to this newspaper report 1,089 pregnant women in Illinois have had COVID-19, and five have died (click here). The Illinois Department of Public Health is cited as the source. The five presumably include S276, S277 & S278 below. Report 2 July

279. An unnamed woman from Chicago contracted Covid-19 at 25 weeks (click here). She was cared for at St. Anthony Hospital in Little Village. She was later diagnosed with pre-eclampsia when she delivered in June but mother and baby are reported to be doing well. Report 2 July.

278. Unique Clay, from Chicago, died of Covid-19 on May 7th, five days after giving birth (click here). Report 9th May.

277. A 31-year-old woman, believed to be Lolita Davis, died of Covid-19 on May 15th, at Roseland Community Hospital in Chicago (click here). Report 3rd July.

276. Eli Solano died of Covid-19 on April 23rd, at Loyola University Medical Center, in Chicago, days after giving birth (click here). Her baby is doing well. Report 25th April.

5 December

275. Erika Becerra contracted Covid19 at 8 months gestation. She gave birth to her son Diego Antonio Becerra normally after induced labour on November 15, in Detroit. Her condition deteriorated and she died on 4 December (click here). Report 4 December.

274. An unnamed obstetrician died from Covid-19 in Lagos University Teaching Hospital, Lagos, Nigeria, in April 2020 (click here). He had reportedly been infected in his private clinic. Report 15 April.

4 December

273. Celma Castro from Brazil contracted Covid 19 at 7 months gestation (click here or here). She was delivered by Caesarean on May 22nd, but died on June 7th. Her daughter survived. Report 3rd December.

272b. Vitebsk Oblast Maternity Hospital in Belarus is currently treating 45 women with the coronavirus infection of whom 25 have already given birth (click here). All babies are healthy. There are reported to be 600 pregnant women with coronavirus in the country. Report 4th December.

272a. Dönüş Kılınç, from Istanbul, Turkey, contracted Covid-19 near to term (click here). She died in childbirth after allegedly being turned away by three hospitals because of her Covid status. The baby survived. Report 3rd December.

1 December

271. Carolina [surname not given], from San Juan del Río gave birth to twins by Caesarean at 33 weeks at Regional General Hospital number 2, in Querétaro, Mexico (click here). The date of the birth was not stated. Report 27 November.

270. Greer Gehler from Anchorage, Alaska, contracted Covid-19 at 20 weeks gestation (click here). The pregnancy is ongoing. Report 27 November.

269. Of 133 maternal deaths in Mumbai between April and October, 29 were directly caused by Covid-19, and a further 24 women who died from other causes had tested positive (click here). At BYL Nair Hospital 8/740 Covid positive women died. Sion Hospital had 14 maternal deaths out of 400 covid positive women. Report 28 November

268. Ashley Duque from Clairemont, San Diego contracted Covid-19 at 17 weeks gestation in March (click here). She required ventilation but recovered and gave birth on August 25th. Report 27 November Previously reported NR 71

267. Jessenia Hernandez from Loxahatchee, Florida contracted severe Covid-19 in October (click here). She was delivered by Caesarean at Palms West Hospital and then transferred to JFK Medical Center for ventilation. She recovered. Report 30 November.

266. Celine Ng-Chan from Singapore contracted Covid-19 in March and gave birth on 7 November (click here). Report 29 November

26 November

265. Sara Gutierrez from Texas contracted Covid-19 at 20 weeks gestation (click here). Report 25 November.

264. Kelly Macfarlane from Nashville, Tennessee, is 33 weeks gestation, the pregnancy is complicated by vasa previa, and she has tested positive for SARS-CoV-2 (click here). A Caesarean birth is planned for next week. Report 26 November.

24 November update

263. Two unnamed Sanömas women, had Covid-19 and their babies died (click here). It is not clear if the mothers were infected in pregnancy or how old the babies were. The women were part of the Yanomami ethnic group, from the village of Auaris, in the Brazilian state of Roraima. Report 24 November.

262. Donna Molina contracted Covid-19 in March at 30 weeks. She required 11 days ventilation, and delivery by Caesarean section at Hackensack University Medical Center in New Jersey (click here). The article also reports Kate Glaser, from upstate New York who contracted Covid-19 at term and delivered normally. Report 21 November.

261. Emily Brown from Tennessee, USA, contracted Covid-19 at 31 weeks in September. She required 20 days ventilation at Erlanger Hospital in McMinn county, during which she was delivered by Caesarean section on September 24 (click here). Report 24 November.

260. In Begaluru, Karnakata, India, 7/300 babies born to women with Covid-19 in Vani Vilas hospital, tested positive. In Gosha hospital, the rate was 15/168, at the Motherhood hospital, 2/35, at Fortis La Femme 1/45, and at Apollo hospital 0/6 (click here). Report 23 November.

19 November update

259. An unnamed woman from Dallas died from Covid-19 on 18 November, shortly after gving birth (click here). Report 18 November

18 November update

258. Gabby Manoz contracted Covid-19 in August and required both ventilation and ECMO at Community Regional Medical Center in Fresno, California, USA (click here). She was delivered at 32 weeks on September 11. Both mother and baby survived. Report 17 November.

17 November update

257. A woman identified only as Ewelina contracted Covid-19 and required both ventilation and ECMO (click here). The baby named Amelka was delivered via caesarean section at 27 weeks early in November at the University Clinical Hospital in Wroclaw, Poland. The mother is now off the ECMO, and no longer ventilated. The baby is recovering. Report 17 November.

256. Perpetual Uke, a rheumatology consultant at Birmingham City Hospital, in the UK, who was pregnant with twins, contracted Covid-19 in March (click here). She required ventilation, and on  April 10 at 26 weeks, delivery by Caesarean. Both her and the twins survived. Report 17 November.

15 November update

255. An unnamed woman (husband Abdul Aziz Bhat) who had tested positive for SARS-CoV-2 gave birth outside the Community Health Center Hajin, the designated Covid-19 Hospital in Bandipora, Jammu & Kashmir, India (click here). Report 15 November.

14 November update

254. Gillian McIntosh contracted severe Covid-19 and gave birth by Caesarean in Abbotsford Hospital, British Columbia, Canada in early November at 38 weeks (click here). She remains on a ventilator. Her baby boy is fine. Report 13 November. Update 31 December. She recovered (click here).

253. Amelia Cortez from Idaho, USA, contracted Covid-19 in May at about 36 weeks gestation. She gave birth soon after but her condition deteriorated and she required ventilation. She survived but six months later still requires respiratory support via an oxygen tank (click here). Report 14 November.

13 November update

252. Madeleine Surges from Duluth, Minnesota, contracted COVID-19 at 38 weeks gestation (click here). The birth is awaited. Report 12 November.

11 November update

251. According to this report about one hundred pregnant women have been infected with the coronavirus in the Helsinki and Uusimaa Hospital District, in Finland, since the pandemic began (click here). Report 10 November.

250. Lissy Yaya contracted Covid-19 at about 28 weeks and gave birth at about the same gestation to baby Jorgito in mid June, during the peak of the pandemic in Peru. Jorgito also tested positive but eventually recovered (click here). Report 11 November.

249. The stories of Blanca Rodriguez R215 below, and Monica Ramirez R242 below, are told in more detail (click here). According to the report another 46 unnamed pregnant women with Covid-19 have also been cared for at Loma Linda University Medical Center, of whom a quarter needed respiratory support. Report 10 November.

7 November update

248. Jessi Jenson age 24 contracted Covid-19 and on Oct. 28 gave birth by caesarean at term (click here). The baby was healthy but a few days later the mother became seriously ill and required ventilation and later transfer to Intermountain Medical Center in Murray, Utah, for ECMO treatment where at the time of writing she remains. Report 6 November.

247. An unnamed 34 year old woman with Covid-19 died on 6 November in Magadan infectious diseases hospital №2 in Magadan, Russia (click here). The baby, born prematurely by caesarean, survived. Report 7 November

3 November update

246. Sharlene Gillies from Birmingham, UK, contracted Covid-19 at 12 weeks (click here). She recovered and on Sept 24th, at 37 weeks, was delivered by Caesarean hysterectomy. The hysterectomy had been planned to treat co-existing cervical cancer. Report 2 November

245. This BBC news report states that between April and June 2020 there were 40 intrapartum stillbirths in England compared with 24 in the same period in 2019 (click here). Report 2 November.

27 October update

244. An unnamed woman tested positive for SARS-CoV-2 and gave birth at San Jorge de Huesca University Hospital in Aragon, Spain (click here). The baby also tested positive. Report 26 October.

243. Sadie Robinson, an American TV actress (Duck Dynasty) contracted Covid-19 early in pregnancy and recovered (click here). The pregnancy is ongoing. Report 26 October.

25 October update

242. Monica Ramirez contracted Covid-19 at 30 weeks (click here). She delivered by Caesarean and was on a ventilator for 3 weeks. She and her baby survived. She had been admitted to Corona Regional Medical Center in San Bernardino County, California in July, and later transfereed to Loma Linda University Medical Center. 48 pregnant women with Covid-19 have been cared for at the latter hospital. Report 24 October.

18 October update

241. Chava Leah bas Esther is seriously ill with Covid-19 in Ichilov Hospital in Tel Aviv (click here). Two weeks following Caesarean birth she remains on a ventilator & ECMO. The baby survived. Report 12 October.

240. Nuha Abu Siam died of COVID-19 on October 8, one month after she gave birth by Caesarean at Soroka Medical Center in Beersheba (click here). She had been treated with ECMO. The baby was unaffected. Report 12 October.

239. This Reuters report suggests that 80% of pregnant women in Bolivia are testing positive for SARS-CoV-2 (click here). Although I’m unaware of any different figures, this seems unlikely. Report 12 October.

238. Emily Donovan contracted Covid-19 and gave birth at 37 weeks at NorthBay Medical Center in Fairfield California, in July (click here). Mother and baby were fine. Report 15 October.

237. Heather Stocks gave birth in August at Diana, Princess of Wales Hospital in Grimsby, UK, after a false positive SARS-CoV-2 test (click here). Report 15 October.

236. Nahid Khan, and about 700 other women with Covid-19, have given birth at Nair hospital in Mumbai, india (click here). She and her baby survived. But eight other women and their babies died. Report 16 October.

235. An unnamed woman with Covid-19 at 23 weeks gestation appealed to the Bombay High Court to be allowed a pregnancy termination (click here). Report 14 October.

6 October update

234. Asfia Samreen contracted severe Covid-19 at 24 weeks gestation and required prolonged ventilation in Abu Dhabi (click here). She recovered and later gave birth to a healthy baby. Report 6 October.

5 October update

233. Pooja Charaniya contracted severe Covid-19 at 23 weeks gestation (click here). She spent 13 days on a ventilator at Texas Health Harris Methodist Hospital Fort Worth, Texas, USA and recovered. On July 22nd at 36 weeks she gave birth to Zayd who is healthy and Covid free. Report 30 September.

232. An unnamed mother infected with SARS-CoV-2 gave birth in the Skane region, in the south of Sweden to a baby who was also infected with SARS-CoV-2 (click here). Report 19 August.

29 September update

231. Thirty four pregnant women with Covid-19 have given birth in Mohali Civil Hospital, Sahibzada Ajit Singh Nagar, India (click here). Report 17 September.

230. Three hundred & seventeen women with SARS-CoV-2 have given birth at Lok Nayak Jai Prakash Narayan (LNJP), the biggest Covid-19 hospital in Delhi, India (click here). 143 were by Caesarean. Only 3 or 4 newborns were infected. Report 28 September.

27 September update

229. Santosh University Hospital, Ghaziabad, India has treated about 50 women with Covid-19 in pregnancy (click here). Some details are given about three infected women with pseudonyms who were delivered by Caesarean at term, and one who had birth induced at 28 weeks gestation. Report 21 September.

26 September update

228. An unnamed pregnant doctor from Indore, India, is reported to have developed Covid-19 twice during her pregnancy (click here). She first tested positive on June 19 and recovered. She tested positive again on September 19. She has mild disease, is being treated at home and the pregnancy is ongoing. Report 21 September.

227. Dr Pratiksha Waldekar (age 32), a pathologist from Amravati, died of Covid-19 at a private hospital in Nagpur, India,on September 20th (click here). She was 7 months pregnant. Her baby had died five days earlier. Report 22 September

226. Mrs Celine Ng-Chan contracted Covid-19 at 10 weeks gestation (click here). The pregnancy continued and she is due to give birth next month in Singapore. Report 26 September

14 September update

225. Sarah Curtis from Distington, Cumbria, UK, contracted Covid-19 shortly before giving birth to twins at 30 weeks (click here and here). Both babies were infected but survived. The pregnancy had been complicated by twin-to-twin tranfusion syndrome, and treated with laser ablation of the placental vessels.  Report 14 September.

13 September update

224. An unnamed woman tested positive and gave birth at 36 weeks in Taipei, Taiwan (click here). The baby tested negative. Report 12 September.

223. An unnamed woman with conflicting SARS-CoV-2 test results gave birth in a private hospital in Mohali, a suburb of Chandigarh, India (click here). Report 13 September.

9 September update

222. Ke’Lin Dillard, age 29, from Baton Rouge Louisiana, contracted Covid-19 and was delivered by Caesarean section in late July (click here). The baby tested negative and survived, but the mother remained on a ventilator and died on August 17. Report 7 Sept

221. An unnamed 23-year-old pregnant woman, with Covid-19 and other complications gave birth by Caesarean section at Government Rajaji Hospital (GRH) in Madurai, India, on August 11th (click here). Her age and clinical details differ from the woman in report 210. Report 8 Sept.

220. Maike Zwalf, from Queensland Australia, a transgender man, who also had cystic fibrosis, contracted Covid-19 at term and gave birth normally (click here). Report 8 Sept.

219. Patricia Alvarez from Baytown, near Houston, Texas, contracted Covid-19 in pregnancy, self-isolated at home and gave birth normally at term (click here). Report 9 Sept.

1 September update

218. An unnamed woman with Covid-19 gave birth at Victoria Hospital in Bangaluru, Karnataka, India on 26 August (click here). The baby died. Report 27 August.

217. An unnamed 39-year-old woman with Covid-19, from Lucban town in Quezon province in the Philippines, gave birth at the government run Quezon Medical Center (QMC) in Lucena city on 25 August (click here). The birth was normal. According to Dr. Belen Garana, head OB-GYN at QMC there has been a rise in pregnant women testing positive over the prevuious two weeks. Most were asymptomatic. Report 28 August.

216. Paropakar Maternity and Women’s Hospital in Kathmandu, Nepal, is opening an isolation facility with 200 beds for suspected and confirmed cases of Covid-19 (click here). So far 100 women have been suspected and one tested positive.. Report 25 August.

215. Blanca Rodriguez contracted Covid-19 at 28 weeks gestation (click here). She required prolonged ventilation, and her baby was delivered by C-section at Loma Linda University Medical Center in California. Both survived. Report 28 August.

214. In Los Angeles County 1,200 pregnant women have tested positive for the virus and two have died. Of 193 babies tested, eight were positive (click here). Report 26 August.

213. In the Indian state of Meghalaya, 877 babies and 61 pregnant women died over the four month COVID-19 pandemic (click here). Only 10 people in the state had died due to COVID-19 directly. According to Director of Health Services, Dr Aman War the maternal and perinatal mortality rate is a sharp rise above normal, largely due to women avoiding normal care and dying of other causes. Report 29 August.

212. Camila Graciano, from Anapolis, in the central Brazilian state of Goias, contracted Covid-19 at 32 weeks gestation (click here). Birth was induced, but she died. The baby survived. Report 26 August.

21 August update

211. An unnamed woman died from Covid-19 on 20th August, seven days after giving birth in Olongapo City in the Philippines (click here). Report 21 August.

20 August update

210. An unnamed woman with surgically corrected mitral valve disease and Covid-19 gave birth at the Rajaji Hospital in Madurai, India on August 13 (click here). Report 20 August.

209. A one-day-old baby born on August 16, at Assam Medical College & Hospital (AMCH) in Dibrugarh, India, tested positive for SARS-CoV-2 (click here). His mother was also positive, but it is not clear whether her test was during or after the pregnancy. Report 20 August.

19 August update

208. Belma Soljanin, age 37, died from Covid-19, 3 days after giving birth at Podhrastovi hospital in Sarajevo. She was head of the institute for mother and child. The baby tested negative and has no symptoms (click here). Report 10 August.  HT Dr Branka Firulovic

18 August update

207. About 28 women have tested positive for SARS-CoV-2 at some point in the pregnancy among those cared for at the National Maternity Hospital in Holles Street, Dublin (click here). Report 17 August.

206. Out of 170 Covid-19 births at Parklands Hospital Dallas, five babies tested positive (click here).  Among them, 28-year-old Yuri Matamoros was seriously ill. She recovered and gave birth to a son Jesus, who tested negative. Note the minor inconsistency with report 200. Report 17 August.

17 August update

205. An unnamed 37-year-old woman, with asymptomatic SARS-CoV-2 gave birth by Caesarean at 47 weeks gestation to a healthy boy at the “Attikon” General Hospital in Athens on 16 August. The baby weighed 2,630g, was in excellent health and was isolated (click here). Report 16 August.

16 August update

204. Eighty eight pregnant women with Covid-19 have delivered in the Indian State of Odisha, of whom 32 gave birth in a dedicated Covid hospital in Ganjam, and 15 in the city of Blasore (click here). All mothers recovered. One baby was infected. Report 15 August.

15 August update

203. Zully, from Stamford Connecticut, contracted severe Covid-19 in April at 8 months gestation. She required ventilation, but both her and the baby survived (click here). Report 11 August.

202. María Alvarez age 24 had SARS-CoV-2 while pregnant but was asymptomatic. She gave birth on July 29th at Peru’s National Perinatal and Maternal Institute, in Lima (click here). Mother & baby were fine. According to the report over 2,000 pregnant women with SARS-CoV-2 gave birth in that hospital between April and the start of August. 120 newborns were reported to have tested positive. Report 12 August.

14 August update

201.  Only one unnamed pregnant woman was diagnosed with Covid-19 in Buenos Aires, Argentina between March 20 and May 5th. She gave birth at Sardá Maternity Hospital. Mother & baby were discharged on April 29 (click here). Over the same period there were 2,200 deliveries in the the 33 public hospitals in Buenos Aires. Report 5th May.

13 August update

200. Wendy Figueroa contracted Covid-19 at 34 weeks and gave birth vaginally at Parkland Hospital in Texas (click here). Her baby Alexa was isolated and tested positive. The case was reported in Study 186 here. This newspaper report also notes that six babies have tested positive at Parkland Hospital out of 128 mothers with SARS-CoV-2 at some point during their pregnancy. Report 13 August. Update 5 November 2021 (click here).

12 August update (Thank you to Dr Christoph Brezinke & Dr Branka Firulovic for alerting me to reports 195-199 from Serbia and Romania)

199. An unnamed 31-year-old woman with Covid-19 died at 22 weeks gestation in Baia Mare hospital on 30 July (click here). The same day a 39-year-old with Covid-19 died at 28 weeks gestation during ambulance transfer between Arad and Timisioara. Report 30 July.

198. On August 8th an unnamed 33-year-old woman with Covid-19 died at 25 weeks gestation in Alba Iulia hopsital, Romania (click here). Report 8 August.

197. This report (click here) describes the two patients below (R195 & R196), and mentions a further pregnant woman from Vranje who was admitted to the Nis Clinical Center on July 3rd with symptoms of the corona virus, but testing negative, who has been on artificial ventilation since July 18. Report 29 July.

196. On 28 July 2020 an unnamed 34-year-old woman with severe Covid-19 pneumonia died after cesarean at 26 weeks gestation in Nis hospital, Serbia (click here). The baby is in neonatal intensive care. Report 28 July.

195. On 21 July 2020 an unnamed 27-year-old woman died from Covid-19 (click here). Her baby had been stillborn the previous day. Both were cared for at Nis hospital, Serbia. Report 21 July.

11 August update

194. Belma Soljanin contracted Covid-19 at 35 weeks (click here). She was delivered by Caesarean on 6 August at the Clinical Centre University Sarajevo Gynecology and Obstetrics Clinic. The baby tested negative and survived, but she died on August 9th in Podhrastovi ward in Sarajevo. Report 9 August.

193. Brittany Lance, from Rockford Illinois, contracted Covid-19 at 28 weeks. She required ventilation and spent 40 days in ICU (click here). Her baby was born prematurely by Caesarean. Report 5 August.

192. Sonam Sreekant contracted mild Covid-19 during her pregnancy (click here). She was nursed at home and recovered. The pregnancy is ongoing. Report 11 August.

191. Nadu Morgan contracted Covid-19 at between 12 and 16 weeks gestation (click here). She was initially treated at Nkhoma Hospital and later transferred to Kamuzu Central Hospital in Lilongwe, Malawi. She recovered. The pregnancy is ongoing.  Report 4 August.

190. Haley Peterson contracted Covid-19 at 19 weeks gestation (click here). Her symptoms were mild and the pregnancy is ongoing. Report 5 August.

189. Ebony Brown-Olaseinde contracted Covid-19 at 27 week gestation with twins. She required ventilation and delivery by Caesarean at 28 weeks at Saint Barnabas Medical Center in Livingston, New .Jersey (click here). Mother & babies survived. Report 6 August.

188. Brittany Hartwell, from Brevard county, Florida, contracted Covid-19 while pregnant. Her baby was born by Caesarean at AdventHealth at 27 weeks (click here). Both recovered, but the baby had a grade 4 intra-ventricular bleed. Report 7 August.

187. An unnamed woman died after childbirth at the Manati Hospital in Puerto Rico on 18 July (click here). Report 22 July.

186. A newborn baby in Basildon tested positive two days after birth on May 11 (click here). The mother, Presley Dowdall, had pre-eclampsia and obstetric cholestasis, but tested negative. Both recovered. Report 30 July.

185. An unnamed 24-year-old woman with COVID-19, gave birth to a healthy daughter at Regional Institute of Medical Sciences, Imphal, India, on August 10th (click here). Report August 10th.

184. Molly Grantham, from North Carolina, contracted Covid-19 postnatally. She developed pneumonia but recovered. Her baby remain uninfected (click here). Report 7 August.

31 July update

183. 19-year-old Janete Vasconcelos da Silva, contracted Covid-19 at 8 months gestation and was cared for at a hospital in Santarem, Para State, Brazil on July 17, 2020 (click here). Report 21 July.

182. There have been 2,842 infections among pregnant and post partum women in Mexico, and 83 deaths (click here). Report 13 July.

181. Three mothers tested positive at the Pumwani maternity hospital in Nairobi, Kenya (click here). No babies were affected. Report 14 July.

180. Amandine tested positive for SARS-CoV-2 and gave birth to Mahaut by Caesarean at CHIREC Delta Hospital in Brussels, Belgium April 25, 2020 (click here). Both mother and baby were doing well. Report 26 April.

30 July update

179. Essence Townsend from Scottsdale, Arizona contracted Covid-19 at about 32 weeks (click here). The pregnancy is ongoing. Report 27 July.

178. Three pregnant women with Covid-19 have been turned away by hospitals in Kolkota, West Bengal (click here). The outcomes appear to have been good. Report 28 July.

177. Kia Anderson, from Memphis, Tennessee, contracted Covid-19 at 23 weeks (click here). She self-isolated at home and recovered. The pregnancy is ongoing. Report 27 July

176. 54 pregnant women have been diagnosed with Covid-19 in El Paso, Texas (click here). No newborns have tested positive. Report 28 July.

175. An unnamed woman gave birth at term at the end of May in Sassoon hospital, Pune, India (click here). She had no symptoms but had SARS-CoV-2 antibodies. The baby had fever, lethargy and signs of severe Covid-19, tested positive and recovered. Report 28 July.

174. Accidental duplicate of Report 72. Veronica Markley contracted Covid 19 at 27 weeks gestation (click here). She was cared for at Presbyterian St. Lukes hospital in Denver, Colorado, and required ventilation for some days. She recovered and gave birth at term. She tested positive again on the day of the birth. The baby was fine. Report 29 July.

27 July update

173. An unnamed woman with Covid-19 gave birth on 22 July at Govind Ballabh Pant Hospital in Agartala, in Tripura, NE India (click here). Both “mother and child are safe”. Report 23 July.

172. An unnamed woman with Covid-19 gave birth at Diphu Medical College & Hospital (DMCH) in Karbi Anglong district in Assam, India (click here). Both mother & child are in a ‘stable’ condition. Earlier Runjun Mahanta and Kankana Barman, who both had Covid-19, gave birth to healthy babies in Kokrajhar, Assam. Report 27 July.

25 July update

171. Kaillee Dyke contracted Covid-19 at 27 weeks gestatiowith twins, and required ventilation in the intensive care unit at Royal Melbourne Hospital, Australia (click here). At the time of the report she remained on the ventilator, the pregnancy was ongoing and the babies were undelivered. Report 19 July.

170. Marzanne Lennox contracted Covid-19 at 30 weeks gestation and required 2 weeks ventilation at Life Wilgers Hospital in Pretoria, South Africa (click here). She survived. The baby was stillborn and delivered by Caesarean. Report 16 July.

20 July update

169. One hundred women with Covid-19 have given birth at Vani Vilas Hospital in Bengaluru, India (click here). The hospital has treated up to 350 pregnant women with Covid-19. Report 17 July.

168. A woman with Covid-19 gave birth by Caesarean at the All India Institute of Medical Sciences (AIIMS)-Patna on 19 July (click here). The baby has not yet been tested. Report 20 July.

167. Ten women with Covid-19 gave birth in Gauhati Medical College and Hospital in Assam, India (click here). Report 19 July.

18 July update

166. Sarah Green from San Antonio in Texas is pregnant and contracted COVID-19 (click here). She is self isolating at home and the pregnancy is ongoing. Report 18 July.

165. Rocio Casalduc from New Hampshire contracted Covid-19 during her pregnancy and was anaeshetised. presumably ventilated, and her baby delivered (click here). Both survived. Report 18 July

15 July update

164. Diana Angola, 36, contracted Covid-19 at 26 weeks. She required ventilation and Caesarean section, at the Versaille clinic in Cali, Colombia (click here). She recovered. Her son Jefferson tested negative and remains in hospital. Report 29 June.

163. Sarah Scully, age 35, from Birmingham UK contracted Covid-19 at a late stage of her prengancy (click here). She was delivered by Caesarean section at Birmingham Women’s Hospital on 12 April. After a month of intensive care she died on May 12. The baby survived. Report 20 June.

162. Aurora Chacon Esparza, age 35, from Minnesota, contracted Covid-19 at 30 weeks gestation. She required ventilation and was delivered by Caesarean at North Memorial Hospital in Brooklyn Minneapolis. The baby survived, but she remains critically ill on a ventilator (click here). Report 11 July. Update 11 August. She died on 18 July (click here).

161. Larissa Blanco was pregnant with twins. She had flu like symptoms and tested positive for SARS- CoV-2 on June 12. The Covid-19 was reported to have been mild. The twins were born at a private hospital in Botucatu, Sao Paulo on June 27, but she died soon after from bleeding (click here). The twins survived. Report 2 July.

160. Dora Nginza Hospital in port Elizbeth S Africa has treated 19 pregnant patients who have tested positive for Covid-19 (click here). The hospital treated its first case in pregnancy on 30 March (click here). Reports 9 April & 24 June.

14 July update

159. Esbeidy Reyes contracted Covid-19 at about 28 weeks, and was admitted to the ICU at Memorial Hermann Hospital in the Texas Medical Center. She was treated with immune plasma from someone who had recovered from the virus (click here). She recovered. The pregnancy is ongoing. Report 28 June.

158. The Institute of Obstetrics & Gynaecology (IOG) & Government Hospital for Women and Children, Egmore, in Chennai, has treated 294 women who tested positive for SARS-CoV-2. None have died.  Kasturba Gandhi Hospital (KGH) for Women and Children, Triplicane has cared for 229 positive women of whom 187 have been discharged, but no further details are available (click here). The Government Kilpauk Medical College Hospital has 30 COVID-19 positive pregnant women. At least 10% of babies are reported to have tested positive. No details were available for Chennai’s largest maternity hospital, Government RSRM Lying-in Hospital, Royapuram. Report 20 June.

157. Morgan Brink, from Johannesburg South Africa, tested positive for SARS-CoV-2 at 22 weeks gestation. She recovered and her son was born by Caesarean at 35 weeks on 11 July. He is recovering (click here). Report 14 July.

13 July update

156. Rocio Martinez contracted Covid-19 at 20 weeks (click here). She recovered, and the pregnancy is ongoing. Report July 8.

155. An unnamed woman from Hesperia, California died from Covid-19 on 26 June (click here). The baby survived and tested negative. According to the report she was the 2nd pregnant woman to die from the disease in California. At the time of the report 72 pregnant women in San Bernardino County had contracted COVID-19. Report 10 July.

154. Maggie Sillero was 28 weeks pregnant with triplets when she tested positive for SARS-CoV-2 (click here). She remained asymptomatic and was delivered by Caesarean at the Woman’s Hospital of Texas in Houston at 32 weeks. The babies all did well. Report 9 July.

153. The wife of professional tennis player Viktor Troicki is pregnant and has tested positive for SARS-CoV-2 (click here). Report 23 June.

26 June update

152. An unnamed 40-year-old woman, with SARS-CoV-2, gave birth to a baby girl at Lagos University Teaching Hospital, Nigeria (click here). Both mother and the baby “are doing fine.” Report 27 April.

24 June update

151. An unnamed 24-year-old woman with Covid-19 and an ectopic pregnancy died in the Gautam Budh Nagar district of Uttar Pradesh, India, on 19 June (click here). Report 20 June.

150. Five pregnant girls have contracted Covid-19 at a state-run children’s shelter in Uttar Pradesh’s Kanpur districy (click here). They are being treated at Kanpur Medical College. No further details. Report 22 June.

149. An unnamed woman with Covid-19 was delivered by Caesarean section at 31 weeks in the Semmelweis Hospital in Budapest (click here). The baby tested negative. Report 23 June.

23 June update

R 20 update. Karen Mannering (report 20 here) gave birth to a healthy baby on 16 June (click here). Report 22 June.

148. A unnamed asymptomatic woman with SARS-Cov2 gave birth to triplets in Mexico on May 8th. (click here). The babies tested positive on the day of birth but are reportedly “not in danger”.  Report 23 June.

147. An unnamed 20-year-old woman who tested positive for coronavirus on June 14 gave birth on June 15 in a COVID care centre in Amravati in Maharashtra. Both mother and baby recovered. Another unnamed woman with COVID-19, from Rohankheda village in Morshi tehsil, gave birth to a boy on June 19 (click here). Both also recovered. Report 22 June.

146. Kate Foxall, 36, from Charminster contracted Covid-19 at 38 weeks, and gave birth to Ostara at St Mary’s Maternity Unit in Poole on May 15 (click here). Ostara’s coronovirus status was not reported but she was fine. Report 22 June.

145. An unnamed  29-year-old woman from Sombrerete in Mexico gave birth to triplets prematurely by Caesarean section on May 6th at Zacatecas Women’s Hospital (click here). She tested positive postnatally. The babies all tested negative. Two died from prematurity. Report 14 May

18 June update

144. Monica V. Garcia from Elizabeth, New Jersey contracted Covid-19 during pregnancy (click here). She recovered without special treatment. The baby is due August 3. Report 22 May.

143. Three pregnant women with Covid-19 in the Cayman Islands recovered with no special treatment (click here). No further details. Report 15 June.

15 June update

142. The Nair hospital in Mumbai successfully completed 302 deliveries of Covid-19 positive women. Doctors said none of the babies born in last two months had tested positive at the time of birth (click here). Report 15 June.

141. An unnamed woman with Covid-19 from Old Dhaka gave birth to a baby boy at Dhaka Medical College Hospital in Bangladesh (click here). Both recovered. Report 17 May.

140. An unnamed woman in late pregnancy tested positive in Meghalaya, Bangladesh (click here). No further details given. Report 10 June.

14 June update

139. Liberian nurse Sedia Marwolo, aged 38, was 32 weeks gestation when she contracted Covid-19 (click here). She recovered and later had a healthy baby. Report 23 May.

Update (click here) of report 17 from Baton Rouge (click here). The mother, who had required ventilation but laboured spontanously at 21+6 days, and whose baby had died soon after birth, is named as Kenna Allen. She recovered. Report 10 June.

138. An unnamed women contracted Covid-19 at 28 weeks gestation, and required delivery at 29 weeks at Dubai’s King’s College Hospital London (click here). The baby was not infected and both recovered. Two other women with less severe disease in the same hospital also recovered and their babies were not infected. Report 11 June.

137. Danielle Wood, age 32, contracted Covid-19  at 32 weeks gestation (click here). She self-isolated at home. Her baby born at 38 weeks was not infected. Report 12 June.

8 June update

136. A woman, identified only as Ilse, developed Covid-19 at 31 weeks gestation (click here). She required ventilation at Rodolfo de Mucha Macías hospital in Mexico City. At 34 weeks she was delivered by Caesarean. The baby tested negative and both recovered. The hospital has cared for four other women with Covid-19. Three recovered and their pregnancies are ongoing. No details were given of the fourth. Report 3rd june.

135. Rusia Goes, aged 42, from Rio de Janeiro developed Covid-19 at 8 months gestion (click here). She required ventilation and delivery by caesarean. The baby tested negative and was isolated from her. She eventually recovered. Report 26 May.

7 June update

134. An unnamed 20 year old woman died after giving birth at 7 months gestation to a stillborn baby in Vellore Medical College and Hospital (click here). The birth was by Caesarean section and the cause of death was reported as complications of pregnancy-induced hypertension. She had tested positive for Sars-Cov2. Report 6 June.

133. 79 pregnant women have tested positive for COVID-19 in Kashmir (click here). Mainly from the Anantnag district. No further details. Report 6 June.

132. Neelam Kumari, age 30, from Ghaziabad in Uttar Pradesh, died in the eighth month of her pregnancy of Covid-19 (click here). Report 7 June.

131. Abi Atkin, aged 34, from Sheffield contracted mild Covid-19 at 34 weeks (click here). She recovered without treatment and gave birth normally at term. Report 6 June.

5 June update

130. An unnamed 22-year-old woman from Padarayanapura, Bengaluru, India, contracted Covid-19 at 8 months gestation (click here). No further details. Report 5th June.

2 June update

129. Michelle Hunter contracted Covid-19 at term (click here). Her son, Hank, was delivered by Caesarean section at an unnamed Vernon, British Columbia hospital. He tested negative. Report 30 May.

1 June update

128. Wafa Boudissa, age 28, died of the coronavirus at 8 months gestation (click here). She was a doctor working in the Intensive Care unit of Ras El Oued hospital in eastern Algeria. Report May 18.

127. A unnamed 28-year-old woman, who was six months pregnant, died in Kalsekar hospital, Mumbra, India after three private hospitals refused to admit her because of suspected Covid-19 (click here). Her death certificate says she died of Acute Respiratory Distress Syndrome (ARDS) with suspected Covid. HT @DeepakNModi. Report 29 May.

31 May update 

126. Vegan lifestyle vlogger Rachel Ama contracted Covid-19 at 11 weeks gestation (click here). She recovered and the pregnancy is continuing. Report 30 May.

30 May update

125. Hilda Garson, age 28, from Manitoba, tested positive for SARS-Cov2 in March (click here). She self isolated, is now 21 weeks, and the pregnancy is ongoing. Three other pregnant women in Manitoba are reported to have tested positive. Report 28 May.

124. Rashmi Kapoor tested positive at term and delivered in Lok Nayak Jai Prakash Narayan Hospital in New Delhi (click here). Report 27 May.

123. Amanda Joyce, from Boston, Massachusetts, contracted Covid-19 on March 19th at about 21 weeks gestation (click here). She self-isolated at home and the pregnancy is ongoing. Report May 29.

28 May update Reports 121 and 122 added.

122. A belated addition. An anonymous woman with Covid-19 in Wuhan (click here) gives birth to an infected baby. Report 5 Feb.

121. Candice Bowie contracted Covid-19 in April in prison in Louisiana at 8 months gestation. On May 4th she was released and went to an unnamed hospital where she was scheduled to deliver by Caesarean (click here). Report 18 May.

26 May update Reports 115-120 added.

120. Diamond, a pseudonym, developed mild Covid 19 at term and delivered at Toronto’s Michael Garron Hospital (click here). Mother and baby survived. Report 21 May.

119. Tasnim Shaheen developed severe Covid-19 at about 28 weeks gestation. She required ventilation and Caesarean at Jamaica Hospital in Queens, New York (click here). Mother and baby are still in hospital but recovering. Report 11 May.

118. An unnamed 20-year-old coronavirus positive woman from Medchal has given birth to twins by Caesarean section at Gandhi Hospital in Hyderabad (click here). The mother was asymptomatic. The twins are awaiting testing. Report 26 May.

117. Lisseth Hernandez developed Covid-19 at 29 weeks gestation with twins. She required ventilation and was delivered at 30 weeks by Caesarean (click here). She recovered. The babies were isolated and did well. Report 19 May.

116. There are 2,561 pregnant women in Russia with coronavirus infection. 2,035 tested positive for SARS-Cov2. Presumably the rest are clinical diagnoses (click here).  There are 816 pregnant women with the coronavirus infection in Moscow alone. Report 25 May.

115. Katie Miller, the spokeswoman for US Vice President Mike Pence, is pregnant and has tested positive for SARS.Cov2 (click here). She has recovered and is back at work. The pregnancy is continuing. Report 26 May.

21 May update Reports 111-114 added.

114. Claire Trusson, age 37, developed Covid-19 at 34 weeks (click here). It was an IVF pregnancy. She gave birth at St Helier Hospital in Carshalton. Both recovered. Report 29 April.

113. Shaquilla James, of Summerton, South Carolina developed Covid-19 at 38 weeks gestation (click here). She gave birth the same day at McLeod Regional Medical Center in Florence, SC, but later was put on a ventilator. Mother & baby both recovered. Report 20 May.

112. Alicia Kappers, age 40, was 31 weeks when she developed Covid-19 on March 24 (click here). She was cared for at the TriHealth Good Samaritan Hospital in Cincinnati, Ohio, where she required prolonged ventilation and a tracheostomy. She went into pre-term labour at 32 weeks and was delivered by Caesarean. The baby tested negative. Both are recovering at home. Report 17 May

111. There have been 115 babies born to Covid-19 infected mothers at the Lokmanya Tilak Municipal General Hospital – also called Sion Hospital – in Mumbai (click here). Three babies were infected, but recovered. Two mothers died, one of whom was aged 28 and died after giving birth.  Report 21 May. (HT Francis Githae Murithi)

18 May update – report 109 added.

110. An unnamed woman with Covid-10 gave birth in the North Ossetia city of Beslan (click here). Both mother and baby are now home. The head of the unnamed hospital’s maternity unit, Hassan Tagaiev, said that 17 of 35 women who were about to give birth there had tested positive for Covid-19.  Report 18 May.

109. Kimberly Phillips, age 44, who had Covid 19, gave birth on May 2nd, at 40 weeks gestation, at the Princess of Wales hospital in Bridgend (click here & here). Her baby, Coolio Carl Justin Morgan, died age 3 days. The primary cause of death was hypoxic ischemic encephalopathy, secondary cause maternal Covid-19. Kimberley is reported to have needed intensive care but has now been discharged. Reports 13, 14 May

17 May update reports 107 & 108 added

108. An unnamed 29-year-old from Sindhupalchowk district in Nepal gave birth on May 6, and died of COVID-19 on May 16, in Kathmandu (click here). Report 17 May

107. An unnamed 27-year-old, from Dharavi slum in Maharashtra, tested positive for coronavirus in Belagavi city on 14 May (click here). She was 7 months gestation. Dharavi is in Mumbai . Belagavi is 500 km to the south. Report 15 May

16 May update – reports 105 & 106 added

106. Ten pregnant women with Covid-19 have been were treated at Sheba Medical Center at Tel Hashomer Hospital in Tel Aviv (click here). Four have given birth, one of whom was in critical condition and was transferred to ICU. Report 15 May.

105. An unnamed woman with SARS-COV-2 gave birth at 39 weeks gestation in Indraprastha Apollo Hospital, New Delhi  (click here). The baby was not infected. Report 15 May.

13 May update – reports 103 and 104 added.

104. Mili América Antelo, age 40, was pregnant with twins at when she developed severe Covid-19 at 28 weeks gestation (click here). She required Caesarean section and spent 11 days in intensive care (7 on a ventilator) at Vall d’Hebron hospital in Barcelona. The twins both tested negative. Mili has now been discharged. Report 11 May.

103. The Los Angles Times reports that roughly 134 pregnant women have tested positive, in LA county (click here). Over 82% of them were symptomatic. There have been 29 live births, and one stillbirth. Twenty-four infants were tested at birth, including one set of twins, and none tested positive. The virus has not been detected in amniotic fluid, breast milk or other “maternal samples”. Report 11 May.

10 May update – cases 97-102 added

102. Six women with COVID-19 have given birth in a government hospital in Peru. Five babies were healthy and have been discharged. The sixth woman remains in a serious condition in the intensive care unit. Her baby was born prematurely and remains hospitalized. None of the babies tested positive for COVID-19 (click here). Report 9 May.

101. Jessa Yager, from Grand island, Nebraska, developed Covid-19 while pregnant  (click here). She is recovering and the pregnancy is ongoing at 36 weeks. Report 7 May.

100. Rachel Bailey from Shelby County, Alabama, was 5-months pregnant when she developed Covid-19 (click here). She is now 30 weeks and recovering. The pregnancy is ongoing. Report 6 May

99. Patient 765, a 20-year-old woman from Padrayanpura, in the late stage of pregnancy, tested positive on 8 May at Vani Villas Women and Children Hospital in Bangalore, Karnataka, India (click here). No further details. Report 9 May.

98. Florette Johnson from Florida, had Covid-19 around term. She had a vaginal birth but later required ventilation (click here). The baby was isolated. Both mother and baby are recovering. Report 9 May.

97. Monique Cook from Atlanta, Georgia, developed Covid-19 at 8 months gestation with twins. She was delivered by Caesarean section at Piedmont Henry hospital on 22 March, and transferred to Piedmont Atlanta hospital for ECMO treatment (click here). She was extubated after 5 days and is now recovering at home.  The twins have also been discharged. Report 8 May

9 May update

96. Gabriela Maia, the wife of Max Johnson, the half brother of British prime minister Boris Johnson, is pregnant, and has Covid-19 (click here). She is recovering. Report 28 March.

95. A baby born at 30 weeks gestation on April 3, in Natal, Brazil, tested positive for SARS- Cov2, and died age 4 days. The mother had respiratory symptoms but her test result was not yet available (click here). The authorities cannot confirm if the infection caused the death. Report 10 April.

8 May update – Cases 86-94 added.

94. Terra Eubanks, a pregnant nurse at Baton Rouge General Hospital in Louisiana, got Covid-19. She recovered (click here). The pregnancy is ongoing. Report 7 May.

93. Johana Rocio Mendoza Chancay, age 40, from Union City, New Jersey, was 26 weeks gestation when she developed Covid-19. She was transferred from Hoboken University Medical Center to Robert Wood Johnson University Hospital in New Brunswick where she gave birth by Caesarean section on March 30th (click here). Her daughter Zion weighed 1lb 13oz. The mother was ventilated and in a coma until April 13. Both recovered. Report 22 April.

92. An unnamed pregnant woman (referred to as P652) had an inconclusive Covid-19 test result at Dr Lal Path Labs in Delhi on 2nd May. The result was interpreted at positive and the woman was nursed on a Covid-19 ward. On May 6, a test at Bangalore Medical College and Research Institute’s Virus Research and Diagnostic Laboratory was declared negative. A third test at the National Institute of Virology’s Bengaluru Field Unit was also negative (click here). Report 8 May.

91. An unnamed pregnant woman is among five Lincolnshire police staff who have tested positive for coronavirus (click here). Report 5 May.

90. Katherine Dawson, aged 36, developed Covid-19 at 32 weeks gestation. She was delivered by Caesarean section at Blackpool Victoria Hospital on 1 April. Her condition deteriorated and she required artificial ventilation (click here). The baby, Ruby, was reported to be infected at birth. Mother and baby recovered, and were discharged on 6 May. Report 6 May.

89. An unnamed  28-year-old women, recovered from Covid-19 and was discharged from Symbiosis Hospital in her 37th week of pregnancy (click here). Report 24 April.

88. An unnamed five-month pregnant woman tested positive for coronavirus at the Pune Municipal Corporation’s Sonawane hospital (click here). She was transferred to Bharati Hospital. Report 14 April.

86. & 87. An unnamed 25-year-old pregnant woman with Covid-19 gave birth by Caesarean section on April 20 at the Sassoon General Hospital in Pune, India, to a healthy boy. Another unnamed woman with Covid-19 delivered by Caesarean section the same day in Aurangabad district civil hospital (click here). Neither baby was infected. Report April 20.

7 May update – cases 80 to 85 added.

85. An unnamed woman with Covid-19 gave birth in Nagaur in Rajustan, India, on April 23 to a baby who also tested positive (click here). Eight other pregnant women from the Ramganj area also tested positive. Report 24 April.

84. An unnamed pregnant woman who had recovered from Covid19 gave birth at her home in Kalnad, Kerala, India after being refused hospital admission (click here). She was later treated at Kannur Medical College Hospital in Pariyaram, before transfer to the General Hospital in Kasaragod for observation. The outcome was not reported. Report 4 May

82 & 83. An unnamed 35-year-old woman from Shangus in south Kashmir’s Anantnag district had Covid-19 at the time of her birth at the SKIMS Medical College Hospital Bemina, Jammu & Kashmir, India (click here). No further details are given. The same report notes that two other pregnant women “have died and nearly 10 have got infected with coronavirus in past two weeks” at the same hospital. It is not clear whether the two women who died had Covid 19. Elsewhere in the same report another woman, Firdousa Javaid is reported to have tested positive in a different maternity hospital, Lalla Ded. Report 6 May.

81. Melissa Brewer from Mountain Green, Utah, whose baby is due in May 2020, had minimal symptoms but tested positive for SARS-CoV2 (click here). The pregnancy is ongoing. Report 5 May.

80. Molly Baldwin, age 28, from Fitchburg, Massachusetts, developed Covid-19 at 33 weeks gestation (click here). She is self-quarantining at home. The pregnancy is ongoing. Report 5 May

5 May update – cases 78 & 79 added

79. An unnamed baby developed Covid-19 at age three months and was treated at Baba Raghav Das Medical College, Gorakhpur, Uttar Pradesh between April 12 and 26th (click here). His mother was SARS-COV-2 negative and continued to breast feed him. The baby recovered and the mother remained negative. Report 5 May.

78. An unnamed woman with Covid-19 gave birth at Aurangabad Civil Hospital in Maharashtra, India (click here). The baby was not infected. Report 5 May.

4 May update – cases 74 to 77 added.

77. Sarita [a pseudonym] from Los Angeles was asymptomatic, but tested positive for SARS-COV-2 during her pregnancy (click here). Her baby, born mid April, was isolated from her and tested negative. At four days of age the baby suffered some sort of respiratory arrest, but recovered. Report 1st May

76. Silvia Leroy, age 35, developed Covid-19 and was transferred from Brookdale, her local hospital, to Mount Sinai hospital in Manhattan (click here). She was on a ventilator for a week, but appeared to be recovering, when she had a cardiac arrest. Her baby, Esther, was delivered by Caesarean section. Sylvia is alive but reported to have brain damage. Report 29 April.

75. Kim Stidworthy, age 25, from New Mexico was 20 weeks gestation when she developed Covid-19 (click here). She spent four days in hospital. The pregnancy is ongoing. Report 1st May.

74. Tamekia Melong, age 37, from Baldwin, Long Island, New York is pregnant and developed Covid-19 in March (click here). The pregnancy is ongoing. Report 3rd May

30 April update – Cases 71 to 73 added. Also up to 10 pregnant women had tested positive for corona virus in the Rotunda Hospital in Dublin (click here) by 1 April. Report 1 April.

73. Alysha Ramos, age 29, pregnant with Covid-19, is in prison in Valparaiso, Indiana (click here & here). Reports 5 & 23 April.

72. Veronica Markley, age 37, from Colorado had Covid-19 at 30 weeks gestation (click here). She was intubated and put on a ventilator at Presbyterian/St. Luke’s Medical Center in Denver, but is recovering. The pregnancy is ongoing. Report 27 April. See report 174. Update 4 March 2021. Both her and the baby recovered (click here).

71. Ashley Duque, age 33, from San Diego developed Covid-19 at 17 weeks gestation (click here). She required 4 days ventilation but is recovering. The pregnancy is ongoing. Report 10 April.

29 April update – Cases 63 to 70 added.  Case 9 – Carrie Symonds, the partner of British Prime Minister Boris Johnson, who gave birth to a healthy baby boy on April 29th, updated. Case 61, an accidental duplicate, deleted. Maternal and baby deaths highlighted in bold.

70. Jennifer Laubach from Clarkston, Michigan, gave birth to twins at 32 weeks at Troy Beaumont Hospital. The babies were isolated because she had symptoms and her partner had Covid-19. She later tested positive (click here). She and the twins recovered. Report 29 April.

69. Abigail Jacobs, age 29, from Kahnawake near Montreal, Canada, developed Covid-19 symptoms in mid March at 24 weeks gestation (click here). Her first test was negative, but a repeat on March 29 was positive. She self-isolated and has recovered. The pregnancy is ongoing. Report 18 April.

68. An unnamed woman from Charlotte, North Carolina, who is three and a half months pregnant tested positive for COVID-19 (click here). Report 14 April.

67. Kim Anderson, age 36 from Idaho Falls developed Covid-19 on March 22nd at about 8 months gestation (click here). She required oxygen therapy in hospital but not ventilation. The pregnancy is ongoing. Report 15 April.

66. A unnamed woman who is four months pregnant is the first pregnant COVID-19 patient admitted to Victoria Hospital in Karnataka, India (click here). Report 31 March.

65. An unnamed pregnant woman age 35 from the Kharpora Kokernag area of Anantnag in Indian administered South Kashmir was admitted to the Maternity and Child Care Hospital in Anantnag (click here). She gave birth to stillborn twins and died soon after. Her test results later confirmed that she was Covid-19 positive. It is reported that Syed Yasir, the commissioner of the region, believes the cause of death was negligence rather than Covid-129. An enquiry is ongoing. Report 27 April.

64. Amanda Joyce, age 33, who works at Newton Wellesley Hospital on the outskirts of Boston, Massachusetts, developed Covid-19 while pregnant (click here). She self-isolated at home, and the pregnancy is ongoing. Report  17 April.

63. Andrea Circle Bear, age 30, from Eagle Butte, South Dakota was pregnant and an inmate in a US Federal prison when she developed Covid-19 (click here). She was transferred to Carswell, a federal prison medical facility in Fort Worth, Texas, and thence to a local hospital where she was delivered by Caesarean section on 2 April. She died on 28 April. The baby’s status was not reported. Report 29 April.

28 April update – cases 58 to 62 added

62. Morgan Brink, age 30, from Roodeport in South Africa, tested positive for coronavirus on 25 March (click here). She had a cough and is self-isolating at home. Report 9 April.

61. Marie Youri, age 19, who had Covid-19, gave birth on 11 April in Yaoundé, the capital of Cameroon (click here). She is on oxygen therapy, & baby Foraya, birth weight 2.1kg, is in isolation. Report 12 April. Accidental duplicate

59 & 60. The deaths of two unidentified women in Mexico (click here). (Report cited in Study 66 here). Report 9th April.

58. Viviane Albuquerque, age 33 from Pernambuco, Brazil, died from Covid-19 at 32 weeks gestation (click here). The baby, delivered by Caesarean, survived. (Report cited in Study 66 (here) which also cites two other newspaper reports of maternal deaths in Brazil, but the links provided miss the reports.) Report 6th April.

26 April update – cases 55 to 57 added

57. Danielle Martin, age 32, from Belfast, Northern Ireland, developed Covid-19 while pregnant with twins at nine weeks (click here). She required artificial ventilation but recovered, and the pregnancy is ongoing. Report 23 April. Update 9 October (click here), she gave birth to healthy twins early in October.

56. Molly Burdick, from Portland in Oregon had Covid-19. 18 days later she was treated for a ruptured (tubal) ectopic pregnancy (click here). She recovered. Report 21 April

55. Sally Nuza, from Ascot, Berkshire developed Covid-19 at 8 months gestation (click here). She recovered, the pregnancy is ongoing, and her unborn baby son is ‘perfectly healthy’. Report 24 April.

24 April update – Cases 53 & 54 added.

54. Wogene Debele from Maryland died of Covid-19 three weeks after giving birth (click here).  Report 23 April

53. Fozia Hanif age 29 developed Covid-19 and gave birth by Caesarean section on 2nd April. She died in Birmingham Heartlands Hospital on April 8th (click here). Report 23rd April

21 April update – Cases 50 to 52 added.

52. Jasmine Jones age 26 from Indianapolis, Indiana, and pregnant with twins, tested positive on March 22nd, at 33 weeks (click here). She was symptomatic, self-isolated at home and the pregnancy is ongoing. Report 20 April.

51.  Silvana Vergara from New York caught the virus at 22 weeks gestation (click here). She was “reassured”, so presumably has recovered and the pregnancy is ongoing, although this is not specifically stated. Report 18 April.

50. Sarah Manning tested positive for SARS-COV-2 a few days before giving birth in Jersey’s midwifery unit (click here). Presumably a normal vaginal birth. Mother and baby are pictured, unmasked, bottle feeding and not separated. Report 20 April.

19 April update Cases 47 to 49 added.

49. An unnamed woman developed symptoms of Covid-19 soon after giving birth in Strong Memorial Hospital, Rochester, New York (click here). Whether she, her partner, or the baby, tested positive has not been disclosed. Report 31 March.

48. Jennifer Kruman, age 33, of Crown Heights, Brooklyn, tested positive 12 hours after giving birth to baby Isaac Hai Kruman, on March 31, at Mount Sinai West Hospital, Manhattan (click here). Isaac tested negative and both went home after 24 hours. Report 17 April.

47. Octobeya Scott, age 30, developed COVID-19 pneumonia at 33 weeks gestation (click here). She was delivered by Caesarean section under general anaesthesia, on March 22 at Jack D. Weiler Hospital of the Albert Einstein College of Medicine, The Bronx, and ventilated for a further five hours. The baby, Alicia Anderson, was separated for five days. Both have now returned home. Report 18 April.

18 April update Cases 42 to 46 added.

46. Salina Shaw, age 37, from Southend in Essex, who had tested positive for Covid-19, gave birth on 4 April and died on 12 April (click here). Report 17 April.

45. Kilee Coye, age 25, from Canastota, New York State, has tested positive for the virus, and has some symptoms. She is 35 weeks pregnant (click here). Her partner also has Covid-19 and is on a ventilator. Report 15 April.

44. Lidia Puerta, age 26, from Spain tested positive at eight months gestation (click here, para 10). She was in quarantine in a hospital in Singapore, and the pregnancy ongoing at the time of the report. Report 22 March.

43. Yanira Soriano, age 36, developed Covid-19 at 34 weeks gestation (click here). She required ventilation and the baby was delivered by caesarean at Southside Hospital in Bay Shore, New York. The baby tested negative. Mother and baby have been discharged. Report 16 April.

42. Megan Sites age 27 from Celina, Ohio, contracted Covid-19 at 29 weeks gestation (click here). She required ventilation, and later ECMO, and the baby was delivered by Caesarean section at 29 weeks. The baby, tested negative twice, is currently on NICU. The mother has improved slightly. Now off ECMO, but still ventilated.  Report 16 April.

16 April update Case 40 & 41 added.

41. Actress Patti Murin, age 39, probably has Covid-19, but has not been tested, and is self-isolating at home in California (click here). She is pregnant and due in July, so about 27 weeks gestation. Report 9 April.

40. Mary Agyeiwaa Boateng, née Agyapong, age 28, died on 12 April, in Luton & Dunstable Hospital UK from Covid-19 (click here). Her baby was reported to be “doing very well”. Report 15 April.

14 April update Cases 35-39 added

39. An unnamed woman with Covid-19 is delivered by Caesarean section at 32 weeks gestation at a public hospital in Nairobi (click here). The obstetrician used a pseudonym because she was not authorised to speak to the media.  No further details were given. Report 13 April.

38. Angela Primachenko age 27 from Vancouver was diagnosed with Covid-19 at 33 weeks and became seriously ill. She gave birth at 34 weeks after induced labour, while being ventilated at Legacy Salmon Creek Medical Center (click here). Her daughter was isolated in intensive care and has tested negative. Mrs. Primachneko has been discharged home. Report 13 April.

35-37. This report in The New York Times (click here) describes Precious Anderson, pregnant & critically ill with Covid-19, and two other unnamed women. The piece also mentions 29 pregnant or delivering women with suspected or confirmed Covid-19 in the Brooklyn Hospital Center. No mother or baby had died, and there had been no confirmed cases among newborns. The Brooklyn Hospital Centre is separate from the Presbyterian Allen Hospital & Columbia Irving Medical Center, so presumably these cases have not been reported in an academic paper yet. Report 12 April.

13 April update Cases 32-34 added. HT @danieladrandic.

34. An unnamed woman, delivered by Caesarean section at the MedLife Grivita private maternity hospital in Bucharest on March 13th, developed pneumonia after birth (click here). A test taken on March 20th was positive and she was transferred to Matei Bals Hospital, the Covid-19 treatment center in Bucharest. At the time of transfer mother and baby were reported to be in good condition (click here). Report 24 March.

33. These ten asymptomatic babies, in a maternity unit in the Romanian city of Timisoara, were apparently not infected in pregnancy or by their mothers (click here). “The mothers tested negative, but the babies tested positive so we have to consider their contacts with medical staff.” Report 7 April.

32. An unnamed mother died in the University Clinic of Gynaecology & Obstetrics in Skopje, North Macedonia. Her baby had died before birth. Neither death was directly due to Covid-19, but according to the report the mother, who had been transferred from Ohrid General Hospital, had her treatment delayed while Covid-19 test results (eventually negative) were awaited. This delay may have contributed to her death (click here). An investigation is ongoing. Report 6 April.

12 April update

31. An unnamed woman with Covid-19 was delivered by Caesarean section in the King Abdullah University Hospital in Irbid, northern Jordan (click here). The baby was isolated from the mother and has reportedly tested negative. Mother and baby doing well. Report 29 March.

30. Sophie Biddle, age 37, was diagnosed with Covid-19 on March 7th, but has recovered (click here). Her 20 week scan on March 23 was reportedly normal and the pregnancy is ongoing. Report 30 March.

10 April update cases 26 – 29 added.

29. An unnamed woman in Ritsona refugee camp 40 miles north of Athens tested positive for Covid-19 a day or two after giving birth (click here). Reort 2 April.

28. 19-year old Marie Youri with Covid-19 gave birth prematurely in Yaounde, Cameroon (click here and here). She is said to be doing well with oxygen treatment. The baby Foraya weighed 2,100 grams and has not displayed any coronavirus symptoms. Report 8 April.

27. An unnamed 22-year-old woman with Covid-19 from Kyengera, Wakiso District, Uganda gave birth by Caesarean Section at Entebbe Grade B Hospital on April 5th (click here). Mother and baby were said to be in good health. Report 6 April.

26. An unnamed pregnant woman from Nallasopara died at Nair Hospital in Mumbai on April 4 (click here). Her baby was reported to have died in-utero before admission. She had been referred from a local hospital in Nallasopara after her condition deteriorated. It is reported that doctors suspect she died of Covid-19. A committee is investigating. Report 7 April.

A separate report (click here) of a 30 year old, nine month pregnant woman dying of Covid-19 in Mumbai may refer to the same woman. Report 6 April.

9 April update case 25 added.

25. Mallory Pease gave birth at Oaklawn Hospital in Marshall, Michigan to daughter Alivia on March 23 at term (click here). She was symptomatic and tested positive for Covid-19. Alivia was not infected. Route of delivery not reported. Mother and baby both now discharged. Report 8 April.

8 April update cases 19 – 24 added.

24. Raquel Iacurto, age 32, a teacher from New York, was admitted to Long Island Jewish Medical Center with respiratory symptoms at 25 weeks gestation on March 11 and tested positive (click here).  She was discharged after three days. The pregnancy is ongoing. Report 28 March.

23. Simone Shoffman, a beauty blogger from Bothwell, near Glasgow in Scotland is pregnant and has tested positive. She is undelivered at home (click here). Report 6 April.

21. & 22. Two unnamed pregnant women with COVID-19 gave birth in Rebagliati Hospital in Lima, Peru, the first on March 22, the second on March 31st, both by Caesarean (click here). Both mothers were reported to be in good health, and neither baby was infected. Report April 8th.

20. Karen Mannering, from Herne Bay, UK, was admitted to the Queen Elizabeth the Queen Mother Hospital in Margate on 21 March with respiratory infection. She tested positive on 25th March, when she was seven months gestation. She has since been discharged home and the pregnancy is ongoing (click here). Report 31 March, updated 1 April.

19. Michelle Wright, aged 37, who is 29-weeks pregnant, has tested positive for coronavirus. The pregnancy is ongoing. She is an inpatient at Russells Hall Hospital in Dudley, UK (click here). Report 7 April.

7 April update cases 16 – 18 added.

18. A newborn baby has reportedly tested positive for coronavirus at James Paget Hospital in Norfolk (click here). No details of the mother have been given. Report 18 March.

17. An unnamed woman with Covid-19 from Baton Rouge, Louisiana, is reported to have gone into preterm labour at 21 weeks (click here). The baby did not survive. The death was reported to the coroner so presumably the baby was born alive. The mother is reported to be on a ventilator. Report 6th April.  The coroner has reportedly decided that the death was due to coronavirus. The mother remains on a ventilator, update 7 April (click here).

16. An unnamed woman with Covid-19 has died during labour at The Whittingdon Hospital, London (click here). The baby survived. Covid-19 has not been ruled out as the cause, and the death has been referred to the Coroner. Report 6 April.

6 April update. Case 10, the first report, scientific or otherwise, of a COVID-19 birth from France, case 11 from Detroit, case 12, the first report from Greece, and two cases 13 & 14 from Egypt added. I’ve also belatedly added a case from Portugal from 17 March.

15. An unnamed woman with Covid-19 (click here) gave birth in Porto’s São João hospital on 17th March. She was described as “doing well”. No further details were given. Report 17 March.

14. An unnamed woman who had recently recovered from COVID-19 gave birth on 4 April by Caesarean section in Hurghada Hospital, (click here). Report 5th April.

13. A 30-year-old eight months pregnant woman infected with COVID-19, treated at Esna Specialized Hospital in Egypt is recovering (click here). The pregnancy is ongoing. Report 3rd April.

12. An unnamed 24 year old woman infected with Covid-19 has given birth at 40 weeks (term) at Attikon General Hospital in Athens, as reported by the state-run news agency ANA-MPA on 27th March (click here). She had tested positive on March 15 and was kept in the hospital for 2 weeks. The baby boy tested negative. No further details are given but both mother and baby are healthy and ready to go home.

11. First reported in the Detroit Free Press, (link broken). For “Click on Detroit” (click here). Jennifer Thompson from Warren, a Detroit suburb, developed symptoms on March 7th at 8 months. She tested positive on March 13th, and her son, Hollis, was born in Beaumont Hospital in Royal Oak, on March 28th. Birth details not reported, but mother and baby back home and doing well. Report 4 April.

10. The artist Ariane Chang @Arianechang describes her baby’s birth by elective Caesarean section under regional block at term on March 19th in “a private birthing clinic in the 15th arrondissement” in Paris, [Presumably Maternité Catholique Sainte Félicité] in the New York Review of Books (click here). She had had symptoms of COVID-19 for two days, and tested positive prior to a second operation under general anaesthesia to control intra-abdominal bleeding, the following day. Baby Clare, reportedly the first baby born to a COVID-19 mother in that clinic, was breast fed but not tested. Mother and baby recovering at home. Ariane Chang illustrates the article with her own paintings and drawings. Report 2nd April.

9. Carrie Symonds, the partner of British Prime Minister Boris Johnson is reported to have had symptoms of Covid-19 for a week (click here and many other sources). According to reports she has not been tested. Since the PM with whom she is living has had confimed COVID-19, it seems likely that she does too. Her due date has been reported as early July. Working back from a hypothetical EDD of 4th July would make her 27 weeks today.  Report 4 April. Update 29 April. She gave birth to a healthy baby boy. Update 11 December 2021. Carrie Symonds had a miscarriage early in 2021, and gave birth to a second child on 9th December 2021 (click here). Report 9 December Update 21 January 2021. Carrie Symonds’ 2nd child, Romy Iris Charlotte Johnson, born on December 9 at University College Hospital in London, contracted Covid aged 5 weeks. She suffered with the virus ‘quite badly’ but is now ‘on the mend’ (click here). Report 19 January

8. Vanesa Muro “a carrier of Covid-19” gave birth to Oscar, birth weight 3.6 kg, by Caesarean on March 13 at the “Madrid hospital in La Paz” [more likely either La Paz university hospital or La Paz maternity hospital in Madrid] (click here).  (El Mundo report click here.) The date of her scheduled Caesarean had been brought forward by three days. Mother and baby were separated for 10 days. Oscar tested negative. Both well. Report 3rd April.

7. Urszula Osborne, age 41, a nurse in Boston Mass, contracted Covid-19 while eight months pregnant (click here). She is recovering and the pregnancy is ongoing. But her husband had severe disease requiring ventilation.  Report 3rd April

6. A 37 year old pregnant woman reportedly infected with Covid-19 died on 29 March after a Caesarean section at the Teresa Herrera Hospital in Coruña. The fetus had reportedly already died (click here). Details conflict, and the family are reported as disputing whether the death was due to Covid-19. An investigation is ongoing (click here). Report 30 March.

5. An unnamed woman age 27 is reported to have died from Covid-19 after giving birth in Łańcut in the south of Poland (click here and here). Report 20th March

4. Allegedly the first birth in Galicia to a mother with Covid-19 (click here). Baby Fabio, born at Álvaro Cunqueiro Hospital in Vigo by Caesarean section at 35 weeks. Birth weight 2.6 kg. Not infected. Mother and baby both doing well. Report 19 March.

3. Model, Michela Persico, partner of Juventus footballer, Daniele Rugani, (click here) is reported to be infected with SARS-COV-2 and is pregnant. The pregnancy is ongoing.  Report 19 March.

2. North Middlesex Hospital UK. Mother with Covid-19 pneumonia gives birth to an infected baby (click here). No further details. Report 14 March.

1 Valentina, is the partner of Matteo, who has been claimed to be Italy’s “patient one”. Matteo was seriously ill with Covid-19, but is reported to be recovering. Valentina is also reported to have developed less severe Covid-19, and is recovering at home. She is reported by La Republica (click here) to be eight months pregnant. At the time of the report, Valentina was undelivered. Report 9 March.

Jim Thornton

Covid-19 in Pregnancy; scientific studies

May 15, 2020

Primary clinical sources

In roughly reverse order. Updated regularly. Click here for ripe-tomato.org’s Covid-19 in pregnancy navigation page.  Curated by Jim Thornton, Keelin O’Donoghue & Kate Walker.

Ongoing update rules. Studies added in the order in which we find them. Study numbers never change (but see below). Inadvertent duplicates deleted. Each study report contains a link to original report, pdf, and full citation. Country, state and city recorded only once for ease of counting.  From February 1st 2021 we will selectively report laboratory studies of stored specimens such as sera and placentae. Such studies are important, but unless they also purport to report original clinical data, there is less need to note duplicate reporting.

Occasional [important] studies include early series, reliable registries, high-quality therapeutic trials in pregnancy (none yet), or basic science.

4 April 2022 – From today we are no longer attempting completeness. We will continue to add papers which seem important. Prior to 4 April we will add all primary sources of which we are aware.

Update 31 July – study 1052 added

Study 1052 – 2,058 cases from India

From BYL Nair Charitable Hospital, Mumbai, and including 318 cases from 18th December 2021 to 24th February 2022, the Omicron wave (click here or study). Citation: Mahajan NN, Kesarwani S, Salunke C, Kumbhar P, Yenkure P, Shaikh J, Shikhare S, Mahale SD, Sachdeva G, Gajbhiye RK. Clinical presentation, pregnancy complications and outcomes of pregnant women with COVID-19 during the Omicron dominant third wave in Mumbai, India. Int J Gynaecol Obstet. 2022 Jul 21. doi: 10.1002/ijgo.14348. Epub ahead of print. PMID: 35861246.

Update 5 June – study 1051 added.

Study 1051 – Infected placentae in the Omicron era in USA

From Northwestern Prentice Women’s Hospital, Chicago, Illinois (click here or study). Citation: Shanes ED, Miller ES, Otero S, Ebbott R, Aggarwal R, Willnow AS, Ozer EA, Mithal LB, Goldstein JA. Placental Pathology After SARS-CoV-2 Infection in the Pre-Variant of Concern, Alpha / Gamma, Delta, or Omicron Eras. Int J Surg Pathol. 2022 May 29:10668969221102534. doi: 10.1177/10668969221102534. Epub ahead of print. PMID: 35645148; PMCID: PMC9152633.

Update 4 May – studies 1049 and 1050 added

Study 1050 – 59 cases of placentitis from UK

From ten centres between March 2020 and March 2021 (click here or study). Citation: Stenton S, McPartland J, Shukla R, Turner K, Marton T, Hargitai B, Bamber A, Pryce J, Peres CL, Burguess N, Wagner B, Ciolka B, Simmons W, Hurrell D, Sekar T, Moldovan C, Trayers C, Bryant V, Palm L, Cohen MC. SARS-COV2 placentitis and pregnancy outcome: A multicentre experience during the Alpha and early Delta waves of coronavirus pandemic in England. EClinicalMedicine. 2022 May;47:101389. doi: 10.1016/j.eclinm.2022.101389. Epub 2022 Apr 15. PMID: 35465646; PMCID: PMC9012107.[important]

Study 1049 – 6,012 cases from Canada

From the CANCOVID-Preg observational surveillance program between March 2020 and October 2021 (click here or study). Citation: McClymont E, Albert AY, Alton GD, Boucoiran I, Castillo E, Fell DB, Kuret V, Poliquin V, Reeve T, Scott H, Sprague AE, Carson G, Cassell K, Crane J, Elwood C, Joynt C, Murphy P, Murphy-Kaulbeck L, Saunders S, Shah P, Snelgrove JW, van Schalkwyk J, Yudin MH, Money D; CANCOVID-Preg Team. Association of SARS-CoV-2 Infection During Pregnancy With Maternal and Perinatal Outcomes. JAMA. 2022 May 2. doi: 10.1001/jama.2022.5906. Epub ahead of print. PMID: 35499852.[important, control group]

Update 10 April – study 1048 added

Study 1048 – 77 self-reported cases from UK

From the COVID-19 Contraception and Pregnancy Study (CAP-COVID) an on-line survey study collecting longitudinal data from pregnant women in the UK between 21st May and 31st December, 2020 (click here or study). Citation: Neerujah Balachandren, Melanie C Davies, Jennifer A Hall, Judith M Stephenson, Anna L David, Geraldine Barrett, Helen C O’Neill, George B Ploubidis, Ephia Yasmin, Dimitrios Mavrelos, SARS-CoV-2 infection in the first trimester and the risk of early miscarriage: a UK population-based prospective cohort study of 3041 pregnancies conceived during the pandemic, Human Reproduction, 2022;, deac062, https://doi.org/10.1093/humrep/deac062

Update 7 April – study 1047 added

Study 1047 – Maternal death from Iran

From Hamadan University of medical sciences (click here or study). Citation: Ghelichkhani, S, Masoumi, SZ, Jalili, E, Parsapour, H, Ali Shirzadeh, A. Maternal death due to COVID-19 and high BMI: A case report from Hamadan, Iran. Clin Case Rep. 2022; 10:e05704. doi:10.1002/ccr3.5704

Update 4 April – studies 1041 to 1046 added

Study 1046 – case report from Japan

From Ibaraki Prefectural Central Hospital, Kasama (click here or study). Citation: Akine D, Sasahara T, Koido A, Abe K, Abe K, Oki A, Takeyasu N, Hashimoto I. Case of a pregnant woman with probable prolonged SARS-CoV-2 viral shedding 221 days after diagnosis. J Infect Chemother. 2022 Mar 28:S1341-321X(22)00091-5. doi: 10.1016/j.jiac.2022.03.012. Epub ahead of print. PMID: 35367149.

Study 1045 – 165 cases from Greece

From various centres (click here or study). Citation: Konstantinidou, A.E., Angelidou, S., Havaki, S., Paparizou, K., Spanakis, N., Chatzakis, C., Sotiriadis, A., Theodora, M., Donoudis, C., Daponte, A., Skaltsounis, P., Gorgoulis, V., Papaevangelou, V., Kalantaridou, S. and Tsakris, A. (2022), Stillbirth due to SARS-CoV-2 placentitis without evidence of intrauterine transmission to fetus: association with maternal risk factors. Ultrasound Obstet Gynecol. Accepted Author Manuscript. https://doi.org/10.1002/uog.24906

Study 1044 – 19 cases from Spain

Collected between March 15 and May 31, 2020, from Barcelona (click here or study). Citation: PALOMO M, YOUSSEF L, RAMOS A, TORRAMADE-MOIX S, Belen MORENO-CASTAÑO A, MARTINEZ-SANCHEZ J, BONASTRE L, PINO M, GOMEZ-RAMIREZ P, MARTIN L, MATEOS EG, SANCHEZ P, FERNANDEZ S, CROVETTO F, ESCOLAR G, CARRERAS E, CASTRO P, GRATACOS E, CRISPI F, DIAZ-RICART M, Differences and similarities in endothelial and angiogenic profiles of preeclampsia and COVID-19 in pregnancy, American Journal of Obstetrics and Gynecology (2022), doi: https://doi.org/10.1016/j.ajog.2022.03.048.

Study 1043 – 10 cases of ECMO from Kuwait

From Al-Jahra ECMO center (click here or study). Citation: Mohammed Bamasood O, Shamsah M, Alfoudri H, Bitar Z, Al Shammari FR, Jagadeesan J, Raj Pandian V, Elkenany Y, Alsarraf AH, Almutawa A, Kh Abdullah T, Mahmoud Ibrahim Mahmoud M. Extracorporeal Membrane Oxygenation in Pregnant Women With COVID-19. ASAIO J. 2022 Apr 1;68(4):471-477. doi: 10.1097/MAT.0000000000001646. PMID: 35349521.

Study 1042 – 155 cases from UK

Underuse of corticosteroids in pregnancy (click here or study). Citation: Närhi F, Moonesinghe SR, Shenkin SD, Drake TM, Mulholland RH, Donegan C, Dunning J, Fairfield CJ, Girvan M, Hardwick HE, Ho A, Leeming G, Nguyen-Van-Tam JS, Pius R, Russell CD, Shaw CA, Spencer RG, Turtle L, Openshaw PJM, Baillie JK, Harrison EM, Semple MG, Docherty AB; ISARIC4C investigators. Implementation of corticosteroids in treatment of COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK: prospective, cohort study. Lancet Digit Health. 2022 Apr;4(4):e220-e234. doi: 10.1016/S2589-7500(22)00018-8. PMID: 35337642; PMCID: PMC8940185.

Study 1041 – Omicron variant in USA

From Parkland Health, Dallas, Texas (click here or study). Citation: Adhikari EH, MacDonald L, SoRelle JA, Morse J, Pruszynski J, Spong CY. COVID-19 Cases and Disease Severity in Pregnancy and Neonatal Positivity Associated With Delta (B.1.617.2) and Omicron (B.1.1.529) Variant Predominance. JAMA. 2022 Mar 24. doi: 10.1001/jama.2022.4356. Epub ahead of print. PMID: 35325015.

Update 11 March – studies 1038 to 1040 added

Study 1040 – 34 cases from USA

From John H. Stroger, Jr. Hospital, Cook County, and AMITA Health Saints Mary and Elizabeth Medical Center, Chicago, between April 1 and August 15, 2020 (click here or study). Possible overlap with study 391, and may include the case reported in study 979. Citation: Peter B, Ree N, Ferrer K, Younes L, Lepe B, Manhal K, Mydam J. Risk Factors Associated With COVID-19 Symptoms and Potential Vertical Transmission During Pregnancy: A Retrospective Cohort Study. Cureus. 2022 Mar 6;14(3):e22900. doi: 10.7759/cureus.22900. PMID: 35265437; PMCID: PMC8898701.

Study 1039 – 208 cases from Ukraine

From Maternity Hospital №1 in Lviv, and Danylo Halytsky Lviv National Medical University, neither of which have previously reported cases (abstract only click here or here, or study). Citation: Markin L, Fartushok T, Mrochko Y, Pidhirnyj Y. MANAGEMENT OF PREGNANT WOMEN WITH COVID-19 – OWN EXPERIENCE. Georgian Med News. 2022 Feb;(323):38-47. PMID: 35271469.

Study 1038 – 2,252 cases from Canada

Pregnant women from Ontario with test dates between March 16, 2020, and January 4, 2022 (click here or study). Citation: Kiera R. Murison, Alicia A. Grima, Alison E. Simmons, Ashleigh R. Tuite, David N. Fisman. Severity of SARS-CoV-2 Infection in Pregnancy in Ontario: A Matched Cohort Analysis. medRxiv 2022.03.04.22271915; doi: https://doi.org/10.1101/2022.03.04.22271915

Update 10 March – study 1037 added

Study 1037 – 1,561 cases from UK

Pregnant women admitted to hospital with covid-19 between 15th December 2021 and 14th January 2022, the period when the omicron variant was dominant (click here or study). These cases have not been included in previous UKOSS reports. Citation: Hilde Marie Engjom, Rema Ramakrishnan, Nicola Vousden, Kathryn Bunch, Edvard P Morris, Nigel Simpson, Christopher Gale, Pat OBrien, Maria Quigley, Peter Brocklehurst, Jennifer J Kurinczuk, Marian Knight. Severity of maternal SARS-CoV-2 infection and perinatal outcomes during the Omicron variant dominant period: UK Obstetric Surveillance System national cohort study. medRxiv 2022.03.07.22271699; doi: https://doi.org/10.1101/2022.03.07.22271699 [important]

Update 4 March – studies 1035 and 1036 added. These two studies report the identical cohort (personal communication Marian Knight).

Study 1036 – 4,436 cases from UK

From UKOSS, pregnant women admitted to hospital with covid-19 related symptoms (click here or study). Citation: Vousden, NP, Ramakrishnan, R, Bunch, K, et al. Management and implications of severe COVID-19 in pregnancy in the UK: data from the UK Obstetric Surveillance System national cohort. Acta Obstet Gynecol Scand. 2022; 00: 1– 10. doi: 10.1111/aogs.14329

Study 1035 – 4,436 cases from UK

From UKOSS, pregnant women admitted to hospital with covid-19 related symptoms (click here or study). Overlap with previous UKOSS publications. Citation: Vousden N, Ramakrishnan R, Bunch K, et al. Severity of maternal infection and perinatal outcomes during periods of SARS-CoV-2 wildtype, alpha, and delta variant dominance in the UK: prospective cohort study BMJ Medicine 2022;1:e000053. doi: 10.1136/bmjmed-2021-000053

Update 3 March – study 1034 added

Study 1034 – 135 omicron wave cases from Turkey & UK

From Sancaktepe Training and Research Hospital, and Koc University Hospital, Istanbul, and St. George’s University Hospital, London, between December 27, 2021 and 01 February 2022 (click here or study). Citation: Birol Ilter, P., Prasad, S., Berkkan, M., Mutlu, M.A., Tekin, A.B., Celik, E., Ata, B., Turgal, M., Yildiz, S., Turkgeldi, E., O’Brien, P., Dadelszen, P.v., Magee, L.A., Kalafat, E., Tug, N. and Khalil, A. (2022), Clinical severity of SARS-CoV-2 infection among vaccinated and unvaccinated pregnancies during the Omicron wave. Ultrasound Obstet Gynecol. Accepted Author Manuscript. https://doi.org/10.1002/uog.24893

Update 23 February – study 1033 added

Study 1033 – 30 cases from France

From Nord Franche-Comté Hospital, Trevenans, which has not previously reported cases (click here or study). Zayet S, Gendrin V, Gay C, Selles P, Klopfenstein T. Increased COVID-19 Severity among Pregnant Patients Infected with SARS-CoV-2 Delta Variant, France. Emerg Infect Dis. 2022 Feb 18;28(5). doi: 10.3201/eid2805.212080. Epub ahead of print. PMID: 35180376.

Update 22 February – studies 1029 to 1032 added

Study 1032 – case from USA

From Northwell Health, Great Neck, New York (click here or study). Citation: Wang KY, Shah P, Pierce M. Convalescent plasma for COVID-19 complicated by ARDS due to TRALI. BMJ Case Rep. 2021 Jan 28;14(1):e239762. doi: 10.1136/bcr-2020-239762. PMID: 33509890; PMCID: PMC7844928.

Study 1031 – case from Saudi Arabia

From Al-Imam Abdulrahman Al-Faisal Hospital, Riyadh (click here or study). Citation: Alhamoud AH, Matary F, Bukhari S, Kelantan M, Bajahzer M. Outcomes of an In Vitro Fertilization Pregnancy With COVID-19 and the Perinatal Outcome in Riyadh, Saudi Arabia. Cureus. 2020 Dec 26;12(12):e12296. doi: 10.7759/cureus.12296. PMID: 33510990; PMCID: PMC7831387.

Study 1030 – case from Italy

From Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan (click here or study). Citation: Giavoli C, Iurlaro E, Morelli V, Rodari G, Ronchi A, Pietrasanta C, Pugni L, Tubiolo D, Properzi P, Pesenti A, Mantovani G, Ferrazzi E, Arosio M. Case Report: Late-Onset Congenital Adrenal Hyperplasia and Acute Covid-19 Infection in a Pregnant Woman: Multidisciplinary Management. Front Endocrinol (Lausanne). 2021 Jan 15;11:602535. doi: 10.3389/fendo.2020.602535. PMID: 33519712; PMCID: PMC7845779.

Study 1029 – case from Italy

From University of Campania “Luigi Vanvitelli”, Naples (click here or study). Citation: Sisti G, Schiattarella A, Sisti A. Treatment of COVID-19 in Pregnancy with Hydroxychloroquine and Azithromycin: a case report. Acta Biomed. 2020 Jul 16;91(4):e2020123. doi: 10.23750/abm.v91i4.10216. PMID: 33525254; PMCID: PMC7927503.

Update 21 February – studies 1026 to 1028 added

Study 1028 – case from USA

From Greater Baltimore Medical Center, Towson, Maryland (click here or study). Citation: Dande R, Qureshi A, Persaud K, Puri C, Zulfiqar S, Awasthi S. Remdesivir in a pregnant patient with COVID-19 pneumonia. J Community Hosp Intern Med Perspect. 2021 Jan 26;11(1):103-106. doi: 10.1080/20009666.2020.1857510. PMID: 33552429; PMCID: PMC7850401.

Study 1027 – case from Spain

From Hospital 12 de Octubre, Madrid (click here or study). Citation: Carbayo-Jiménez T, Carrasco-Colom J, Epalza C, Folgueira D, Pérez-Rivilla A, Barbero-Casado P, Blázquez-Gamero D, Galindo-Izquierdo A, Pallás-Alonso C, Moral-Pumarega MT. Severe Acute Respiratory Syndrome Coronavirus 2 Vertical Transmission from an Asymptomatic Mother. Pediatr Infect Dis J. 2021 Mar 1;40(3):e115-e117. doi: 10.1097/INF.0000000000003028. PMID: 33565817.

Study 1026 – case from Denmark

From Landssygehuset, Tórshavn (click here or study). Citation: Ravn A, Eysturoy A, Reynstind D, Nielsen CM, Walther-Larsen S. [Preterm delivery by cesarean section in a woman with severe COVID-19 pneumonia]. Ugeskr Laeger. 2021 Feb 1;183(5):V10200779. Danish. PMID: 33570033.

Update 20 February – studies 1016 to 1025 added

Study 1025 – miscarriage in Morocco

From Centre Hospitalier Universitaire Hassan II, Fès, (click here or study). Citation: Saoud MK, Lamsyah S, Mamouni N, Errarhay S, Bouchikhi C, Banani A. Fausse couche de 8 semaines d´aménorrhée chez une patiente positive au virus SARS-CoV-2 [8 amenorrhea week miscarriage in a patient positive for the SARS-CoV-2 virus]. Pan Afr Med J. 2020 Oct 22;37(Suppl 1):26. French. doi: 10.11604/pamj.supp.2020.37.26.23445. PMID: 33456650; PMCID: PMC7796836.

Study 1024 – case from China

From Zhongshan City People’s Hospital, Zhongshan, (click here or study). Likely also reported in studies 3, 57, 81, 192, 433, 493 and 974. Citation: Liao X, Cheng Z, Wen J, Li B. A Case Report of Sedation Strategy for a Patient With Coronavirus Disease 2019 Supported by Extracorporeal Membrane Oxygenation After Cesarean Section. Heart Surg Forum. 2021 Jan 14;24(1):E019-E021. doi: 10.1532/hsf.3459. PMID: 33635242.

Study 1023 – case from USA

From Tampa General Hospital, Florida (click here or study). Citation: Clough BM. Triple Threat: Postpartum, Coronavirus Disease 2019 Positive, and Requiring Extracorporeal Membrane Oxygenation. Air Med J. 2021 Mar-Apr;40(2):124-126. doi: 10.1016/j.amj.2020.12.009. Epub 2021 Jan 2. PMID: 33637276; PMCID: PMC7834374.

Study 1022 – case from UK

From Blackpool Victoria Hospital (click here or study). Citation: George H, Mutema E. A COVID 19 positive preterm mother and infant: a case report. J Obstet Gynaecol. 2021 Nov;41(8):1262-1264. doi: 10.1080/01443615.2020.1863343. Epub 2021 Mar 1. PMID: 33645405.

Study 1021 – case from Iran

From RobatKarim Hospital, Tehran, (click here or study). Citation: Aminimoghaddam S, Afrooz N, Nasiri S, Motaghi Nejad O, Mahmoudzadeh F. A COVID-19 pregnant patient with thrombotic thrombocytopenic purpura: a case report. J Med Case Rep. 2021 Mar 1;15(1):104. doi: 10.1186/s13256-020-02577-5. PMID: 33648584; PMCID: PMC7919244.

Study 1020 – case from India

DFrom Dr TMA Pai Hospital, Udupi, Karnataka (click here or study). Citation: Kumar V, Narayanan P, Shetty S, Mohammed AP. Lower motor neuron facial palsy in a postnatal mother with COVID-19. BMJ Case Rep. 2021 Mar 1;14(3):e240267. doi: 10.1136/bcr-2020-240267. PMID: 33649026; PMCID: PMC7929834.

Study 1019 – two cases from Mexico

From Mexico city (click here or study). Can’t guess the hospital. Citation: Lima-Rogel V, Villegas-Silva R, Coronado-Zarco A, Estrada-Ruelas I, Vega ARS, Muro-Flores RH, Villa-Guillén M. Perinatal COVID-19: a case report, literature review, and proposal of a national system for case record. Bol Med Hosp Infant Mex. 2021;78(1):34-40. English. doi: 10.24875/BMHIM.20000230. PMID: 33661873.

Study 1018 – case from India

From Amrita Institute of Medical Sciences and Research Centre, Kochi, which has not previously reported cases (click here or study). Citation: Kappanayil M, Balan S, Alawani S, Mohanty S, Leeladharan SP, Gangadharan S, Jayashankar JP, Jagadeesan S, Kumar A, Gupta A, Kumar RK. Multisystem inflammatory syndrome in a neonate, temporally associated with prenatal exposure to SARS-CoV-2: a case report. Lancet Child Adolesc Health. 2021 Apr;5(4):304-308. doi: 10.1016/S2352-4642(21)00055-9. Epub 2021 Mar 4. PMID: 33675696; PMCID: PMC7929789.

Study 1017 – four cases from Gabon

From Libreville Mother and Child University Hospital, which has not previously reported cases (click here or study). Citation: Minkobame U, Mveang Nzoghe A, Maloupazoa Siawaya AC, Alame-Emane AK, Ndong Sima CAA, Mvoundza Ndjindji O, Zang Eyi C, Ndong Mintsa A, Padzys GS, Meye JF, Djoba Siawaya JF. Case series of SARS-COV-2 infection in pregnant African women: focus on biological features. J Med Virol. 2021 Jul;93(7):4147-4151. doi: 10.1002/jmv.26927. Epub 2021 Mar 26. PMID: 33710650; PMCID: PMC8251219.

Study 1016 – two cases from the Netherlands

From Reiner de Graaf Gasthuis, Delft, and Erasmus University Medical Center, Rotterdam (click here or study). Citation: Smeele HT, Perez-Garcia LF, Grimminck K, Schoenmakers S, Mulders AG, Dolhain RJ. Systemic lupus erythematosus and COVID-19 during pregnancy. Lupus. 2021 Jun;30(7):1188-1191. doi: 10.1177/09612033211002270. Epub 2021 Mar 14. PMID: 33715506; PMCID: PMC8120627.

Update 19 February – studies 1006 to 1015 added

Study 1015 – case from Mexico

From UMARE Reproduction Clinic, Mexico City (click here or study). Citation: Oropeza Chávez L, Sánchez Tinajero Á, Martínez Orozco JA, Becerril Vargas E, Dolores De la Merced A, Ruíz Santillán DP, Delgado Cueva AI, Alvarado Peña N. A 34-Year-Old Woman with a Diamniotic Dichorionic Twin Pregnancy Presenting with an Erythematous and Papular Skin Rash Associated with SARS-CoV-2 Infection. Am J Case Rep. 2021 Mar 20;22:e929489. doi: 10.12659/AJCR.929489. PMID: 33743006; PMCID: PMC7990122.

Study 1014 – case from Spain

From University and Polytechnic La Fe Hospital, Valencia (click here or study). Citation: Martínez-Varea A, Desco-Blay J, Monfort S, Hueso-Villanueva M, Perales-Marín A, Diago-Almela VJ. Transitory Fetal Skin Edema in a Pregnant Patient with a Mild SARS-CoV-2 Infection. Case Rep Obstet Gynecol. 2021 Mar 16;2021:5552877. doi: 10.1155/2021/5552877. PMID: 33763271; PMCID: PMC7962876.

Study 1013 – case from Mexico

From Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Mexico City (click here or study). Citation: Valdespino-Vázquez MY, Helguera-Repetto CA, León-Juárez M, Villavicencio-Carrisoza O, Flores-Pliego A, Moreno-Verduzco ER, Díaz-Pérez DL, Villegas-Mota I, Carrasco-Ramírez E, López-Martínez IE, Giraldo-Gómez DM, Lira R, Yocupicio-Monroy M, Rodríguez-Bosch M, Sevilla-Reyes EE, Cortés-Bonilla M, Acevedo-Gallegos S, Merchant-Larios H, Cardona-Pérez JA, Irles C. Fetal and placental infection with SARS-CoV-2 in early pregnancy. J Med Virol. 2021 Jul;93(7):4480-4487. doi: 10.1002/jmv.26965. Epub 2021 Apr 6. PMID: 33764543; PMCID: PMC8250563.

Study 1012 – case from Turkey

From Sehit Prof. Dr. Ilhan Varank Training and Research Hospital, Istanbul (click here or study). Citation: Tekin AB, Zanapalioglu U, Gulmez S, Akarsu I, Yassa M, Tug N. Guillain Barre Syndrome following delivery in a pregnant woman infected with SARS-CoV-2. J Clin Neurosci. 2021 Apr;86:190-192. doi: 10.1016/j.jocn.2021.01.028. Epub 2021 Feb 2. PMID: 33775326; PMCID: PMC7993757.

Study 1011 – case from Morocco

From Cheikh Khalifa International University Hospital, Casablanca (click here or study). Citation: Aasfara J, Hajjij A, Bensouda H, Ouhabi H, Benariba F. A unique association of bifacial weakness, paresthesia and vestibulocochlear neuritis as post-COVID-19 manifestation in pregnant women: a case report. Pan Afr Med J. 2021 Jan 13;38:30. doi: 10.11604/pamj.2021.38.30.27646. PMID: 33777298; PMCID: PMC7955605.

Study 1010 – case from Russia

From First Moscow State Medical University Named after I.M. Sechenov, Moscow (click here or study). Citation: Sukhikh G, Petrova U, Prikhodko A, Starodubtseva N, Chingin K, Chen H, Bugrova A, Kononikhin A, Bourmenskaya O, Brzhozovskiy A, Polushkina E, Kulikova G, Shchegolev A, Trofimov D, Frankevich V, Nikolaev E, Shmakov RG. Vertical Transmission of SARS-CoV-2 in Second Trimester Associated with Severe Neonatal Pathology. Viruses. 2021 Mar 10;13(3):447. doi: 10.3390/v13030447. PMID: 33801923; PMCID: PMC7999228.

Study 1009 – four cases from India

From Vardhaman Mahavir Medical College & Safdarjung Hospital, New Delhi (click here or study). Citation: Marwah S, Kanwar R, Naghma S, Dabral A, Gupta N. A Clinical Study on Initial Experience of COVID-19 ARDS in Obstetric Patients at a Tertiary Care Centre in India. Case Rep Obstet Gynecol. 2021 Mar 29;2021:5591041. doi: 10.1155/2021/5591041. PMID: 33815855; PMCID: PMC8010524.

Study 1008 – case from Iran

From Mazandaran University of Medical Sciences, Sari (click here or study). Citation: Farhadi R, Mehrpisheh S, Ghaffari V, Haghshenas M, Ebadi A. Clinical course, radiological findings and late outcome in preterm infant with suspected vertical transmission born to a mother with severe COVID-19 pneumonia: a case report. J Med Case Rep. 2021 Apr 23;15(1):213. doi: 10.1186/s13256-021-02835-0. PMID: 33892788; PMCID: PMC8063577.

Study 1007 – case from Nepal

From KIST Medical College, and Teaching Hospital, Lalitpur, which has not previously reported cases (click here or study). Citation: Thapa B, Acharya S, Karki S. Vertical Transmission of COVID-19: A Case Report and Review of Literature. J Nepal Health Res Counc. 2021 Apr 23;19(1):203-205. doi: 10.33314/jnhrc.v19i1.3312. PMID: 33934161.

Study 1006 – case from USA

Abstract only (click here or study). Authors affiliated with Fort Worth, Texas and Denver, Colorado. Citation:Harenberg JL, Church R, Tubog TD. Anesthesia Considerations of a Pregnant Woman With COVID-19 Undergoing Cesarean Delivery: A Case Report. AANA J. 2020 Aug;88(4):47-53. PMID: 33944772.

Update 18 February – studies 1001 to 1005 added

Study 1005 – case report from Mexico

From Hospital “Dalinde”, Mexico City (click here or study). Citation: Mendoza-Hernández M, Huerta-Niño de Rivera I, Yoldi-Negrete M, Saviñon-Tejeda P, Franco-Cendejas R, López-Jácome LE, Navarro-Castellanos I. Probable Case of Vertical Transmission of SARS-CoV-2 in a Newborn in Mexico. Neonatology. 2021;118(3):364-367. doi: 10.1159/000514710. Epub 2021 May 6. PMID: 33957638; PMCID: PMC8247818.

Study 1004 – case report from China

From Guangzhou Women and Children’s Medical Center, Guangzhou Medical University, Guangzhou, (click here or study). Citation: He JR, Xiao YH, Ding W, Shi YL, He X, Liu XD, Zhang GZ, Li SS, Su JQ, Liang L, Zeng L, Li F, Qiu X. Maternal, placental and neonatal outcomes after asymptomatic SARS-CoV-2 infection in the first trimester of pregnancy: A case report. Case Rep Womens Health. 2021 Jul;31:e00321. doi: 10.1016/j.crwh.2021.e00321. Epub 2021 May 4. PMID: 33968612; PMCID: PMC8095019.

Study 1003 – case report from the Philippines

From Philippine General Hospital, Manila (click here or study). Citation: Garcia JJ, Turalde CW, Bagnas MA, Anlacan VM. Intravenous immunoglobulin in COVID-19 associated Guillain-Barré syndrome in pregnancy. BMJ Case Rep. 2021 May 11;14(5):e242365. doi: 10.1136/bcr-2021-242365. PMID: 33975846; PMCID: PMC8118003.

Study 1003 – two cases from USA

From Danbury Hospital, Connecticut (click here or study). Citation: Ogamba I, Chuang L, Panarelli E, Zilberman D. A case report of COVID-19 infection and management during pregnancy. SAGE Open Med Case Rep. 2021 May 16;9:2050313X211015899. doi: 10.1177/2050313X211015899. PMID: 34035922; PMCID: PMC8132078.

Study 1002 – twin pregnancy from Italy

From University of Bari “Aldo Moro” (click here or study). Citation: Resta L, Vimercati A, Sablone S, Marzullo A, Cazzato G, Ingravallo G, Mazzia G, Arezzo F, Colagrande A, Rossi R. Is the First of the Two Born Saved? A Rare and Dramatic Case of Double Placental Damage from SARS-CoV-2. Viruses. 2021 May 26;13(6):995. doi: 10.3390/v13060995. PMID: 34073492; PMCID: PMC8230224.

Study 1001 – case report from Iran

From Shahid Beheshti University of Medical Sciences, Tehran (click here or study). Citation: Mehrpour M, Arab M, Hadavand F, Khalafi M, Khalafi M. A case report of Guillain-Barré syndrome in a pregnant woman infected by COVID-19. Acta Neurol Belg. 2021 Aug;121(4):1079-1080. doi: 10.1007/s13760-021-01696-0. Epub 2021 Jun 3. PMID: 34080170; PMCID: PMC8172359.

Update 14 February – studies 992 to 1000 added

Study 1000 – one infected mother in South Africa

From University of Botswana, Gaborone (click here or study). Citation: Nakstad B, Kaang T, Gezmu AM, Strysko J. Nosocomial SARS-CoV-2 transmission in a neonatal unit in Botswana: chronic overcrowding meets a novel pathogen. BMJ Case Rep. 2021 Jun 7;14(6):e242421. doi: 10.1136/bcr-2021-242421. PMID: 34099450; PMCID: PMC8186748.

Study 999 – case report from Hong Kong (China)

From Queen Elizabeth hospital (click here or study). Citation: Yeung KSK, Kwok CY, Chow YF. Anaesthesia in a patient with COVID-19 undergoing elective lower segment caesarean section: a case report. Hong Kong Med J. 2021 Jun;27(1):210-212. doi: 10.12809/hkmj208944. Epub 2021 Jun 11. PMID: 34127562.

Study 998 – two cases from India

From Tata Main Hospital, Jamshedpur (click here or study). Possible overlap with studies 650, 950 and 978. Citation: Singh V, Choudhary A. Treatment With Remdesivir in Two Pregnant Patients With COVID-19 Pneumonia. Cureus. 2021 May 12;13(5):e14986. doi: 10.7759/cureus.14986. PMID: 34131531; PMCID: PMC8195547.

Study 997 – two cases from UK

From St Mary’s Hospital, London (click here or study). Citation: Pikovsky M, Tan MY, Ahmed A, Sykes L, Agha-Jaffar R, Yu CKH. Euglycaemic ketoacidosis in pregnant women with COVID-19: two case reports. BMC Pregnancy Childbirth. 2021 Jun 16;21(1):427. doi: 10.1186/s12884-021-03928-w. PMID: 34134652; PMCID: PMC8207493.

Study 996 – case report from UK

From Shrewsbury & Telford hospital (click here or study). Citation: Sanders-Davis LJ, Ritchie J. Appendicitis with concurrent COVID-19 infection in a patient during the third trimester of pregnancy. BMJ Case Rep. 2021 Jun 23;14(6):e242651. doi: 10.1136/bcr-2021-242651. PMID: 34162616; PMCID: PMC8230971.

Study 995 – case report frm USA

From Piedmont Medical Center, Atlanta, Georgia (click here or study). Citation: Roberts J, Cheng JD, Moore E, Ransom C, Ma M, Rogers BB. Extensive Perivillous Fibrin and Intervillous Histiocytosis in a SARS-CoV-2 Infected Placenta From an Uninfected Newborn: A Case Report Including Immunohistochemical Profiling. Pediatr Dev Pathol. 2021 Nov-Dec;24(6):581-584. doi: 10.1177/10935266211025122. Epub 2021 Jun 28. PMID: 34176361.

Study 994 – case report from China

From Renmin Hospital of Wuhan University (click here or study). Citation: Peng L, Khan S, Ali A, Ahmed S, Ali L, Han G, Jing Y. Vertical transmission potential of SARS-CoV-2 from infected mother to twin neonates. Future Virol. 2021 May:10.2217/fvl-2020-0324. doi: 10.2217/fvl-2020-0324. PMID: 34181703; PMCID: PMC8221022.

Study 993 – case report from Iran

From the Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran,(click here or study). Citation: Shahidi Dadras M, Rakhshan A, Diab R, Abdollahimajd F. SARS-CoV-2 infection as a potential triggering factor for urticarial vasculitis during pregnancy: A case report. Clin Case Rep. 2021 Jun 24;9(6):e04323. doi: 10.1002/ccr3.4323. PMID: 34194805; PMCID: PMC8223884.

Study 992 – 8 cases from Iran

From Besat Hospital, Sanandaj from March to May 2020 (click here or study). Citation: Sheikhahmadi S, Behzadi S, Karimi A, Zakaryaei F. Evaluating Vertical Transmission of COVID-19 from Mothers to Neonates: An Iranian Case Series of 8 Patients. Arch Iran Med. 2021 May 1;24(5):405-408. doi: 10.34172/aim.2021.58. PMID: 34196206.

Update 13 February – studies 953 to 991 added

Study 991 – case report from USA

From University of Texas Health, San Antonio (click here or study). Citation: Pfeiffer AF, James R, Neuhoff BK, Pfeiffer WB, Lowery DR, Rizvi SAA. The Deleterious Effects of COVID-19 in the Peripartum Period: A Case Report. Pediatr Rep. 2021 Jun 16;13(2):334-339. doi: 10.3390/pediatric13020041. PMID: 34208425; PMCID: PMC8293368.

Study 990 – case report from Romania

From “Bucur” Maternity, Saint John Hospital, Bucharest (click here or study). Citation: Lesnic A, Haj Hamoud B, Poenaru MO, Moldovan VT, Chicea R, Sima RM, Popescu M, Ples L. Can SARS-CoV-2 Induce Uterine Vascular Anomalies and Poor Contractile Response?-A Case Report. Medicina (Kaunas). 2021 Jun 29;57(7):670. doi: 10.3390/medicina57070670. PMID: 34209533; PMCID: PMC8303955.

Study 989 – case report from India

From Indraprastha Apollo Hospital, New Delhi (click here or study). Citation: Shankar V, Dhar P, George J, Sharma A, Raj A. Eclampsia and posterior reversible encephalopathy syndrome in a parturient complicated by SARS COVID-19 pneumonia. Braz J Anesthesiol. 2021 Sep-Oct;71(5):576-578. doi: 10.1016/j.bjane.2021.06.008. Epub 2021 Jun 29. PMID: 34214521; PMCID: PMC8239311.

Study 988 – case report from USA

From Rush University Medical Center, Chicago (click here or study). Citation: Testani E, Twiehaus S, Waters T, Pombar X. Conscious prone positioning in a pregnant patient with COVID-19 respiratory distress: A case report and review. Case Rep Womens Health. 2021 Jul;31:e00339. doi: 10.1016/j.crwh.2021.e00339. Epub 2021 Jun 29. PMID: 34221902; PMCID: PMC8239207.

Study 987 – case report from India

Abstract only available on PubMed (click here or study). Citation: Bedi N, Aggarwal P, Dang A, Nigam A. Transplacental COVID Antibodies and Cytokine Storm in Newborn: Presence of Antibodies does not Indicate Protection Always! J Assoc Physicians India. 2021 Jan;69(1):76-77. PMID: 34227782.

Study 986 – case report from Germany

Hospital not named (click here or study). Citation: Ackermann M, Jonigk DD. Microvascular placental alterations in maternal COVID-19. Am J Obstet Gynecol. 2022 Jan;226(1):135-136. doi: 10.1016/j.ajog.2021.06.098. Epub 2021 Jul 3. PMID: 34228972; PMCID: PMC8254388.

Study 985 – 4 maternal deaths in Turkey

From Diyarbakir Gazi Yasargil Research and Training Hospital, Diyarbakır (click here or study). Citation: Bağlı İ, Öcal E, Yavuz M, Uzundere O, Bozkurt F. Maternal deaths due to COVID-19 disease: The cases in a single center pandemic hospital in the south east of Turkey. J Obstet Gynaecol Res. 2021 Nov;47(11):4067-4076. doi: 10.1111/jog.14928. Epub 2021 Jul 12. PMID: 34254718; PMCID: PMC8447164.

Study 984 – case report from Iran

From Ghaem Hospital, Mashhad (click here or study). Citation: Alirezaei S, Vatanchi A, Pourali L, Aminzadeh B, Latifnejad Roudsari R. Mortality of a postpartum woman presented with massive vulvar edema in association with Covid-19: a case report with clinical and radiological findings. BMC Infect Dis. 2021 Jul 13;21(1):678. doi: 10.1186/s12879-021-06175-8. PMID: 34256733; PMCID: PMC8276204.

Study 983 – case report from Turkey

From Zonguldak Bulent Ecevit University, Zonguldak (click here or study). Citation: Akdemir Y, Haciseyitoglu D, Celebi G, Aydemir C, Bahadır B, Cakir AT, Barut A, Ozmen U. Probable viremia and positive placental swabs for SARS-CoV-2 in a preterm pregnant woman with mild COVID-19. J Med Virol. 2021 Dec;93(12):6788-6793. doi: 10.1002/jmv.27202. Epub 2021 Jul 28. PMID: 34260081; PMCID: PMC8426688.

Study 982 – case report from Spain

From Hospital Universitari Vall d’Hebron, Barcelona (click here or study). Citation: Piñana M, Abril JF, Andrés C, Silgado A, Navarro A, Suy A, Sulleiro E, Pumarola T, Quer J, Antón A. Viral populations of SARS-CoV-2 in upper respiratory tract, placenta, amniotic fluid and umbilical cord blood support viral replication in placenta. Clin Microbiol Infect. 2021 Oct;27(10):1542-1544. doi: 10.1016/j.cmi.2021.07.008. Epub 2021 Jul 11. PMID: 34260951; PMCID: PMC8272946.

Study 981 – case report from Qatar

From Hamad Medical Corporation, Doha (click here or study). May be included in studies 364 and 407, but the clinical details differ from studies 577 and 605. Citation: Hailan YMA, Sayed G, Yassin MA. COVID-19 in a pregnant patient with beta-thalassemia major: A case report. Clin Case Rep. 2021 Jul 11;9(7):e04331. doi: 10.1002/ccr3.4331. PMID: 34267898; PMCID: PMC8272935.

Study 980 – two cases from USA

From NYU Langone Hospital, New York (click here or study). Citation: Hanna N, Lin X, Thomas K, Vintzileos A, Chavez M, Palaia T, Ragolia L, Verma S, Khullar P, Hanna I. Underestimation of SARS-CoV-2 infection in placental samples. Am J Obstet Gynecol. 2021 Nov;225(5):572-575.e1. doi: 10.1016/j.ajog.2021.07.010. Epub 2021 Jul 21. PMID: 34297970; PMCID: PMC8294065.

Study 979 – case report from USA

Cared for at AMITA Health, Saints Mary and Elizabeth Medical Center, Chicago (click here or study). Citation: Mydam J, Younes L, Siddiqui M, Tarsha T. Death from COVID-19 in a Hispanic postpartum woman and review of the literature. BMJ Case Rep. 2021 Jul 23;14(7):e242819. doi: 10.1136/bcr-2021-242819. PMID: 34301683; PMCID: PMC8311310.

Study 978 – case report from India

From Tata Main Hospital, Jamshedpur, so possibly also included in studies 650 and 950 (click here or study). Citation: Choudhary A, Singh V, Bharadwaj M, Barik A. Pregnancy With SARS-CoV-2 Infection Complicated by Preeclampsia and Acute Fatty Liver of Pregnancy. Cureus. 2021 Jun 14;13(6):e15645. doi: 10.7759/cureus.15645. PMID: 34306855; PMCID: PMC8279907.

Study 977 – case report from Germany

From Hannover Medical School, Hannover, which has not previously reported cases (click here or study). Citation: Düppers AL, Bohnhorst B, Bültmann E, Schulz T, Higgins-Wood L, von Kaisenberg CS. Severe fetal brain damage subsequent to acute maternal hypoxemic deterioration in COVID-19. Ultrasound Obstet Gynecol. 2021 Sep;58(3):490-491. doi: 10.1002/uog.23744. PMID: 34319630; PMCID: PMC8441859.

Study 976 – case report from India

From Military Hospital Kirkee, Pune, which has not previously reported cases (click here or study). Citation: Karade S, Vishal AK, Sen S, Bewal N, Gupta RM. Probable vertical transmission of severe acute respiratory syndrome coronavirus 2 infection from mother to neonate. Med J Armed Forces India. 2021 Jul;77(Suppl 2):S490-S493. doi: 10.1016/j.mjafi.2020.11.026. Epub 2021 Jul 26. PMID: 34334918; PMCID: PMC8313057.

Study 975 – case report from USA

It is not possible to identify the hospital from author affiliations (click here or study). Citation: Shields AD, Byrne JJ, Munisteri M, Wood M. Survival from Maternal Cardiac Arrest Complicating Coronavirus Disease 2019. Case Rep Obstet Gynecol. 2021 Jul 19;2021:3762198. doi: 10.1155/2021/3762198. PMID: 34336319; PMCID: PMC8292066.

Study 974 – case report from China

From Zhongshan People’s Hospital (Zhongshan Hospital of Sun Yat-Sen University) (click here or study). The clinical features suggest this is the same patient previously reported in studies 3, 57, 81, 192, 433, and 493. Citation: Huang W, Cheng Z, Liao X, Wang L, Wen J, Li J, Jiang H, Yuan Y, Li B. Postpartum extracorporeal membrane oxygenation of a woman with COVID-19-related acute respiratory distress syndrome: A case report. Medicine (Baltimore). 2021 Jul 30;100(30):e26798. doi: 10.1097/MD.0000000000026798. PMID: 34397736; PMCID: PMC8322481.

Study 973 – case report from the Philippines

From Philippine General Hospital, Manila (click here or study). Citation: Cuaño PMGM, Pilapil JCA, Larrazabal RJB, Villalobos RE. Acquired tracheoesophageal fistula in a pregnant patient with COVID-19 pneumonia on prolonged invasive ventilation. BMJ Case Rep. 2021 Aug 20;14(8):e244016. doi: 10.1136/bcr-2021-244016. PMID: 34417243; PMCID: PMC8381298.

Study 972 – case report from UK

From Chelsea and Westminster Hospital, London (click here or study). Citation: Agbontaen KO, Somasundram K, Baker M. Critical COVID-19 in a 24-week pregnant woman with 32 days of invasive mechanical ventilation before delivery of fetus: a case of successful collaborative multidisciplinary care. BMJ Case Rep. 2021 Sep 8;14(9):e243516. doi: 10.1136/bcr-2021-243516. PMID: 34497055; PMCID: PMC8438726.

Study 971 – two cases from Sweden

From Örebro University Hospital, which has not previously reported cases (click here or study). Citation: Östling H, Ugarph-Edfeldt M, Hildén K. Two cases of severe COVID-19 in gestational week 27 and 28 respectively, after which both pregnancies proceeded to term. Int J Obstet Anesth. 2021 Nov;48:103212. doi: 10.1016/j.ijoa.2021.103212. Epub 2021 Aug 18. PMID: 34500190; PMCID: PMC8372455.

Study 970 – two cases from Taiwan

From Mackay Memorial Hospital, Taipei, which has not previously reported cases (click here or study). Citation: Chang WH. COVID-19 pandemic’s effects on the quality of pregnant women’s emergency treatment: Review of two cases from a medical center in northern Taiwan. Taiwan J Obstet Gynecol. 2020 Nov;59(6):795-800. doi: 10.1016/j.tjog.2020.09.003. Epub 2020 Sep 10. PMID: 33218391; PMCID: PMC7832363.

Study 969 – case report from Taiwan

From Taipei Veterans General Hospital (click here or study). The clinical details differ from those of study 968. Citation: Wang LM, Lai SP, Liang SJ, Yang ST, Liu CH, Wang PH. Maternal and fetal outcomes of the pregnant woman with COVID-19: The first case report in Taiwan. Taiwan J Obstet Gynecol. 2021 Sep;60(5):942-944. doi: 10.1016/j.tjog.2021.07.045. Epub 2021 Aug 2. PMID: 34507681; PMCID: PMC8326015.

Study 968 – case report from Taiwan

From Taipei Veterans General Hospital, which has not previously reported cases (click here or study). Citation: Yang ST, Yeh CC, Lee WL, Lee FK, Chang CC, Wang PH. A symptomatic near-term pregnant woman recovered from SARS-CoV-2 infection. Taiwan J Obstet Gynecol. 2021 Sep;60(5):945-948. doi: 10.1016/j.tjog.2021.07.046. Epub 2021 Aug 3. PMID: 34507682; PMCID: PMC8328571.

Study 967 – case report from Indonesia

Cared for at Cipto Mangunkusumo General Hospital, which has not previously reported cases (click here or study). Citation: Irwinda R, Wibowo N, Prameswari N. Cytokines storm in COVID-19 with dengue co-infection in pregnancy: Fatal maternal and fetal outcome. IDCases. 2021;26:e01284. doi: 10.1016/j.idcr.2021.e01284. Epub 2021 Sep 6. PMID: 34513593; PMCID: PMC8420090.

Study 966 – case report from Poland

From the Regional Specialist Hospital Megrez in Tychy, which has not previously reported cases (click here or study). Citation: Urban A, Dyrda M. Mother and neonate suffering from COVID-19 infection. Is there any risk of vertical transmission? A case report. Ginekol Pol. 2021;92(10):701-703. doi: 10.5603/GP.a2021.0033. Epub 2021 Sep 20. PMID: 34541649.

Study 965 – case report from Mexico

From Ángeles del Pedregal Hospital, Mexico City, which has not previously reported cases (click here or study). Citation: Morales HSG, Cortés DV, Hernández HS, Guiot ML, Torres GCR, Camacho FMR, Montoya GA, Maldonado BF, Bárcenas JG, López GGP. Vertical transmission: evidence of COVID-19 in a twin pregnancy. JBRA Assist Reprod. 2022 Jan 17;26(1):153-157. doi: 10.5935/1518-0557.20210058. PMID: 34542252; PMCID: PMC8769174.

Study 964 – case report from Turkey

From Manisa City Hospital, which has nt previously reported cases (click here or study). Citation: Yangin Ergon E, Akbay S, Aytemiz G, Avcı Çelik EC, Çalıskan Polat A, Umit Z, Paytoncu S. A novel case of neonatal acute respiratory distress syndrome with SARS-CoV-2 infection: potential perinatal transmission. Arch Argent Pediatr. 2021 Oct;119(5):e531-e535. English, Spanish. doi: 10.5546/aap.2021.eng.e531. PMID: 34569757.

Study 963 – case report from Japan

From Okayama (click here or study). The hospital is not named, and the authors give only their university affiliations. However, there have been no previous cases reported from this city. Citation: Yamamoto K, Hagiya H, Maki J, Okahara S, Hasegawa K, Otsuka F. High-Dose Corticosteroids for a Pregnant Woman Critically Ill With Coronavirus Disease 2019. Cureus. 2021 Aug 23;13(8):e17398. doi: 10.7759/cureus.17398. PMID: 34584807; PMCID: PMC8457894.

Study 962 – 5 cases from Italy

From the University Hospital of Parma (click here or study). Four of the cases appear to have been reported in study 109, reference not cited. Citation: Giordano G, Petrolini C, Corradini E, Campanini N, Esposito S, Perrone S. COVID-19 in pregnancy: placental pathological patterns and effect on perinatal outcome in five cases. Diagn Pathol. 2021 Oct 3;16(1):88. doi: 10.1186/s13000-021-01148-6. PMID: 34602071; PMCID: PMC8487453.

Study 961 – case report from Canada

From St. Michael’s Hospital, Toronto, Ontario, which has not previously reported cases (click here or study). Citation: Naeh A, Berezowsky A, Yudin MH, Dhalla IA, Berger H. Preeclampsia-Like Syndrome in a Pregnant Patient With Coronavirus Disease 2019 (COVID-19). J Obstet Gynaecol Can. 2021 Oct 12:S1701-2163(21)00752-0. doi: 10.1016/j.jogc.2021.09.015. Epub ahead of print. PMID: 34648956; PMCID: PMC8505022.

Study 960 – case report from USA

[Currently neither abstract nor full text available] (click here or study). Citation: Dalla S, Rausch M, Kellerman R. Case Report: Second-Trimester Maternal COVID-19 Infection and Tetralogy of Fallot. Am Fam Physician. 2021 Oct 1;104(4):331. PMID: 34652122.

Study 959 – case report from Spain

From Hospital San Pedro de Alcántara, Cáceres, which has not previously reported cases (click here or study). Citation: Márquez Isidro EM, García García MJ, Solo de Zaldívar Tristancho M, Romero Peguero R. SARS-CoV-2 and prematurity. Any evidence of vertical transmission? An Pediatr (Engl Ed). 2021 Nov;95(5):375-377. doi: 10.1016/j.anpede.2021.05.005. Epub 2021 Oct 8. PMID: 34670719; PMCID: PMC8498649.

Study 958 – 26 cases from China

Cared for at Tongji Hopital, Wuhan, from January 23, to March 23, 2020, and presumably reported many times (click here or study). Citation: Ding L, Xiong X, Yu G, Li C, Wang H, Yang Y, Wu S, Cai X. Nursing Care of 26 Infants Born to Mothers With COVID-19. Adv Neonatal Care. 2022 Feb 1;22(1):15-21. doi: 10.1097/ANC.0000000000000958. PMID: 34670953; PMCID: PMC8815632.

Study 957 – case report from Romania

From the National Institute of Mother and Child Care, Alessandrescu-Rusescu, Bucharest, which has not previously reported cases (click here or study). Citation: Radoi V, Pop LG, Bacalbasa N, Panaitescu AM, Ciobanu AM, Cretoiu D, Toader OD. Fatal Association of Mirror and Eisenmenger Syndrome during the COVID-19 Pandemic. Medicina (Kaunas). 2021 Sep 28;57(10):1031. doi: 10.3390/medicina57101031. PMID: 34684068; PMCID: PMC8537604.

Study 956 – case report from India

From Goa Medical College, Bambolim, which has not previously reported cases (click here or study). Citation: Bakhle A, Sreekumar K, Baracho B, Sardessai S, Silveira MP. Cavitary lung lesions in a neonate: Potential manifestation of COVID-19 related multisystem inflammatory syndrome. Pediatr Pulmonol. 2022 Jan;57(1):311-314. doi: 10.1002/ppul.25732. Epub 2021 Oct 29. PMID: 34714960; PMCID: PMC8661966.

Study 955 – case report from Ireland

From Our Lady of Lourdes Hospital, Drogheda, which has not previously reported cases (click here or study). Citation: Brady A, Aglan A. Critical COVID-19 in a pregnant patient who presented in starvation ketoacidosis with a background history of acrorenal syndrome. BMJ Case Rep. 2021 Nov 2;14(11):e244117. doi: 10.1136/bcr-2021-244117. PMID: 34728503; PMCID: PMC8565554.

Study 954 – case report from Brazil

Cared for at the Hospital das Clínicas of the Faculty of Medicine of the University of São Paulo, which has not previously reported cases (click here or study). Citation: Avila WS, Kirschbaum M, Devido MS, Demarchi LMMF. COVID-19, congenital heart disease, and pregnancy: dramatic conjunction-case report. Eur Heart J Case Rep. 2021 Jul 24;5(10):ytab291. doi: 10.1093/ehjcr/ytab291. PMID: 34729452; PMCID: PMC8557342.

Study 953 – case report from Spain

From Hospital Universitari Germans Trias i Pujol, Badalona (click here or study). May have been included in study 177. Citation: Velasco I, Soldevila B, Julián T, García-Riaño N, Puig-Domingo M. Euglycemic diabetic ketoacidosis and COVID-19: A combination to foresee in pregnancy. J Diabetes. 2022 Jan;14(1):88-89. doi: 10.1111/1753-0407.13237. Epub 2021 Nov 19. PMID: 34729932.

Update 12 February – studies 928 to 952 added

Study 952 – case report from Poland

Cared for at the Tertiary University Hospital in Wroclaw (click here or study). The dates suggest not included in study 908. Citation: Rosner-Tenerowicz A, Fuchs T, Zimmer-Stelmach A, Pomorski M, Trzeszcz M, Zwierzchowski J, Zimmer M. Placental pathology in a pregnant woman with severe COVID-19 and successful ECMO treatment: a case report. BMC Pregnancy Childbirth. 2021 Nov 10;21(1):760. doi: 10.1186/s12884-021-04228-z. PMID: 34758757; PMCID: PMC8579174.

Study 951 – case report from Spain

From Hospital Universitario Puerta de Hierro Majadahonda (click here or study). Possibly included in studies 125, 151, 177, 196 and 443. Citation: González Rockmore D, Tung-Chen Y, Gómez Nicolás C, Díaz de Santiago A. Importance of point-of-care ultrasound in early diagnosis of COVID-19 complications. BMJ Case Rep. 2021 Nov 11;14(11):e246311. doi: 10.1136/bcr-2021-246311. PMID: 34764124; PMCID: PMC8587469.

Study 950 – 4 cases from India

From Tata Main Hospital, Jamshedpur, which has not previously reported cases (click here or study). Citation: Kumar S, Choudhary A, Shukla R, Singh V, Ranjan R. Moderate to Severe Thrombocytopenia in Four Pregnant Women With Asymptomatic COVID-19 Infection. Cureus. 2021 Oct 6;13(10):e18531. doi: 10.7759/cureus.18531. PMID: 34765332; PMCID: PMC8575279.

Study 949 – case report from Poland

From PCK Marine Hospital in Gdynia, which has not previously reported cases (click here or study). Citation: Brzezinski M, Brzezinska N, Rusek U, Broniecki K. Acute respiratory distress syndrome in pregnant women infected with SARS-CoV-2 – a case report. Pol Merkur Lekarski. 2021 Oct 22;49(293):356-360. PMID: 34800023.

Study 948 – case report from USA

From The Brooklyn Hospital Center, New York, which has not previously reported cases (click here or study). Citation: Kahlon GK, Zylak A, Leblanc P, Kondamudi N. Fetal Gallstones in a Newborn after Maternal COVID-19 Infection. Case Rep Pediatr. 2021 Nov 18;2021:3688173. doi: 10.1155/2021/3688173. PMID: 34804624; PMCID: PMC8601857.

Study 947 – case report from Romania

From the Emergency Clinical County Hospital, Cluj-Napoca, which has not previously reported cases (click here or study). Citation: Trancǎ SD, Antal O, Farcaş AD. Case Report: Acute Splenic Artery Thrombosis in a COVID 19, Postpartum Patient. Front Med (Lausanne). 2021 Nov 5;8:698627. doi: 10.3389/fmed.2021.698627. PMID: 34805195; PMCID: PMC8604041.

Study 946 – case report from Iran

Cared for at Imam Ali Hospital, Alborz (click here or study). The clinical features differ from those in studies 584 and 887. Citation: Nagdi Dorabati P, Khoshnam Rad M, Hedayat Yaghoobi M, Mahmoodi Z. A Pregnant Mother Infected With Severe Acute Respiratory Syndrome Coronavirus 2 With Substance Dependence: A Case Report. J Addict Nurs. 2021 Oct-Dec 01;32(4):260-262. doi: 10.1097/JAN.0000000000000437. PMID: 34855325.

Study 945 – 4 cases from India

From King George’s Medical University, Lucknow, which has not previously reported cases (click here or study). Citation: Singh R, Agrawal A, Asnani M. Remdesivir in Pregnant Patients with Novel Coronavirus Disease 2019: Case Series. J Obstet Gynaecol India. 2021 Dec 2:1-3. doi: 10.1007/s13224-021-01589-5. Epub ahead of print. PMID: 34873384; PMCID: PMC8637515.

Study 944 – 29 cases from Turkey

Pregnant women with covid, treated with favipavir, and reported to the Clinical Pharmacology and Toxicology Unit, Ataturk Research Hospital, Izmir, from 1 September to 31 December 2020 (click here or study). Possible overlap with other reports from Turkey. Citation: Tırmıkçıoğlu Z. Favipiravir exposure and pregnancy outcome of COVID-19 patients. Eur J Obstet Gynecol Reprod Biol. 2022 Jan;268:110-115. doi: 10.1016/j.ejogrb.2021.12.001. Epub 2021 Dec 6. PMID: 34902747; PMCID: PMC8647391.

Study 943 – case report from Indonesia

From Dr. Kariadi General Hospital, Semarang, which has not previously reported cases (click here or study). Citation: Santosa D, Sofro MAU, Farida, Nindita N, Pangarsa EA, Setiawan B, Rizky D, Suharti C. A full-term pregnant woman with secondary Evans syndrome caused by severe coronavirus disease 2019: a case report. J Med Case Rep. 2021 Dec 13;15(1):606. doi: 10.1186/s13256-021-03205-6. PMID: 34903274; PMCID: PMC8667974.

Study 942 – case report from Iran

From Mashhad University of Medical Science, Mashhad, which has not previously reported cases (click here or study). Citation: Moeindarbary S, Dadgar S, Layegh P, Shahriari Z, Fayyaz F, Danesteh S, Rafiee M, Bahrami M. Extensive bilateral diffuse infiltrates and deterioration of lung following infection with severe acute respiratory syndrome coronavirus 2 in a pregnant woman: a case report. J Med Case Rep. 2021 Dec 13;15(1):588. doi: 10.1186/s13256-021-03156-y. PMID: 34903276; PMCID: PMC8667013.

Study 941 – 2 cases from Switzerland

Probably cared for at Lausanne University Hospital (click here or study). May be included in study 922. Citation: Favre G, Mazzetti S, Gengler C, Bertelli C, Schneider J, Laubscher B, Capoccia R, Pakniyat F, Ben Jazia I, Eggel-Hort B, de Leval L, Pomar L, Greub G, Baud D, Giannoni E. Decreased Fetal Movements: A Sign of Placental SARS-CoV-2 Infection with Perinatal Brain Injury. Viruses. 2021 Dec 15;13(12):2517. doi: 10.3390/v13122517. PMID: 34960786; PMCID: PMC8706116.

Study 940 – case report from USA

From Bethesda Hospital East, Boynton Beach, Florida, which has not previously reported cases (click here or study). Citation: Campbell M, Palati S, Sanchez A, Castaneda M. A Case of Recovery From COVID-19 Pneumonia in Pregnancy After Vaginal Delivery in ICU. Cureus. 2021 Nov 24;13(11):e19862. doi: 10.7759/cureus.19862. PMID: 34976489; PMCID: PMC8712199.

Study 939 – case report from Iran

From Firoozgar Hospital, Iran University of Medical Sciences, Tehran (click here or study). Possibly included in study 345, but the clical features differ from the case reported in study 664. Citation: Dini P, Aminimoghaddam S, Mirzaasgari Z, Rahimian N, Khotbehsara ST, Abolmaali M. Spontaneous Intracerebral Hemorrhage (ICH) associated with pregnancy and SARS-CoV-2 infection: a case report. BMC Pregnancy Childbirth. 2022 Jan 6;22(1):14. doi: 10.1186/s12884-021-04345-9. PMID: 34986833; PMCID: PMC8731675.

Study 938 – case report from Sri Lanka

From De Soysa Hospital for Women, Kynsey Road, Colombo, which has not previously reported cases (click here or study). Citation: Rishard M, Perera S, Jayasinghe K, Rubasinghe A, Athapaththu S, Edirisinghe M, Ranaweera P, Ranawaka T, Kaluarachchi A, Jayawardana P, Haniffa Z. An Unusual Presentation of COVID-19 Associated Multisystem Inflammatory Syndrome in Adults (MIS-A) in a Pregnant Woman. Case Rep Obstet Gynecol. 2022 Jan 7;2022:4186846. doi: 10.1155/2022/4186846. PMID: 35013694; PMCID: PMC8742152.

Study 937 – case report from USA

From Overland Park Regional Medical Center, Kansas City, which has not previously reported cases (click here or study). Citation: Wang G, Stapley E, Peterson S, Parrott J, Clark-Ganheart C. Persistent Fetal SVT in a COVID-19 Positive Pregnancy. Case Rep Obstet Gynecol. 2022 Jan 7;2022:9933520. doi: 10.1155/2022/9933520. PMID: 35013695; PMCID: PMC8742150.

Study 936 – 292 cases from India

Out of 292 pregnant women with Covid, cared for at Gandhi Medical College, Hyderabad, six developed AKI and are reported in detail (click here or study). This centre has not previously reported cases. Citation: Vadakkeveetil AK, Yadla M, Cherian A, Rahul, Goli M, Chada R, Nazneen S. Coronavirus disease 2019 and pregnancy-related acute kidney injury: Our initial experience of six cases. Saudi J Kidney Dis Transpl. 2021 Mar-Apr;32(2):559-563. doi: 10.4103/1319-2442.335471. PMID: 35017353.

Study 935 – case report from Romania

From Bucharest (click here or study). It is not possible to idetify the hospital from author affiliations. Citation: Bohîlțea RE, Margareta Mihai B, Munteanu O, Ducu I, Adrian Dumitru V, Gheorghe CM, Augustin Georgescu T, Varlas V, Vlădăreanu R. Early prenatal diagnosis of an atypical phenotype of sacral spina bifida. J Med Life. 2021 Sep-Oct;14(5):716-721. doi: 10.25122/jml-2021-0292. PMID: 35027976; PMCID: PMC8742886.

Study 934 – case report from India

Cared for at Mahatma Gandhi Memorial Medical College, Indore, which has not previously reported cases (click here or study). Citation: Dave A, Joshi P, Jaiswal S, Kapdeo P. Successful outcome of severe COVID-19 in pregnancy: individualised approach. BMJ Case Rep. 2022 Jan 17;15(1):e246648. doi: 10.1136/bcr-2021-246648. PMID: 35039364; PMCID: PMC8768493.

Study 933 – case report from France

From either Bordeaux or Clermont-Ferrand. It is not possible to determine the hospital from author affiliations (click here or study). Citation: Zalle I, Barthelemy Y, Piperata A, Galvaing G, Camilleri L, d’Ostrevy N. Low fetal age is not a contraindication for extracorporeal membranous oxygenation in COVID-19-related ARDS. J Card Surg. 2022 Jan 20. doi: 10.1111/jocs.16251. Epub ahead of print. PMID: 35060195.

Study 932 – 15 cases from USA

Treated with monoclonal antibody at Ronald Reagan UCLA Medical Center, which has not previously reported cases (click here or study). Citation: Richley M, Rao RR, Afshar Y, Mei J, Mok T, Vijayan T, Weinstein S, Pham CU, Madamba J, Shin CS, Suda D, Han CS. Neutralizing Monoclonal Antibodies for Coronavirus Disease 2019 (COVID-19) in Pregnancy: A Case Series. Obstet Gynecol. 2022 Feb 3. doi: 10.1097/AOG.0000000000004689. Epub ahead of print. PMID: 35115451.

Study 931 – case report from USA

A 31-year-old woman pregnant with twins contracted COVID-19 at 16 weeks’ gestation (click here or study). The babies were delivered by Caesarean at 26 weeks. From author affiliations cared for at California Pacific Medical Center, San Francisco, which has not previously reported cases. Citation: Retajczyk CT, Jaffee IM, McKim KJ, Retajczyk PJ, Mueller CM. Premature twin neonates with a Coronavirus-19 positive mother present with an unusual pattern of intestinal ischemia. J Pediatr Surg Case Rep. 2022 Mar;78:102173. doi: 10.1016/j.epsc.2021.102173. Epub 2022 Jan 29. PMID: 35127444; PMCID: PMC8800498.

Study 930 – case report from Canada

A 27-year-old woman with Covid and an in-utero fetal death, delivered at 24+5 (click here or study). From author affiliations cared for at Vernon Jubilee Hospital in British Columbia, which has not previously reported cases. Citation: Bewley DJ, Lee J, Popescu O, Oviedo A. SARS-CoV-2 Placental Infection in an Unvaccinated Mother Resulting in Fetal Demise. Cureus. 2021 Dec 30;13(12):e20833. doi: 10.7759/cureus.20833. PMID: 35141086; PMCID: PMC8800441.

Study 929 – 63 cases from Italy

From the “Guglielmo da Saliceto” Hospital in Piacenza (click here or study). Possible overlap with studies 117, 252 and 356. Citation: Ghiselli S, Laborai A, Biasucci G, Carvelli M, Salsi D, Cuda D. Auditory evaluation of infants born to COVID19 positive mothers. Am J Otolaryngol. 2022 Feb 5;43(2):103379. doi: 10.1016/j.amjoto.2022.103379. Epub ahead of print. PMID: 35144104; PMCID: PMC8816906.

Study 928 – 3,042 cases from USA

De-identified electronic medical record data in the Cerner HealtheDataLab platform, including 82 healthcare facilities, from December 2019 to September 2020 (click here or study). Likely overlap with study 677, and other US series. Citation: Hsu AL, Ohler AM, Goldstein A, Truong S, Tang CY, Wan XF, McElroy JA. Coronavirus Disease 2019 (COVID-19) Disease Severity: Pregnant vs Nonpregnant Women at 82 Facilities. Clin Infect Dis. 2022 Feb 11;74(3):467-471. doi: 10.1093/cid/ciab441. PMID: 35148386.

Update 11 February – studies 922 to 927 added

Study 927 – 68 cases from 12 countries

The centres can be inferred from author affiliations (click here or study). Likely inclusion in many other series. Citation: Schwartz DA, Avvad-Portari E, Babál P, Baldewijns M, Blomberg M, Bouachba A, Camacho J, Collardeau-Frachon S, Colson A, Dehaene I, Ferreres JC, Fitzgerald B, Garrido-Pontnou M, Gerges H, Hargitai B, Helguera-Repetto AC, Holmström S, Irles CL, Leijonhfvud Å, Libbrecht S, Marton T, McEntagart N, Molina JT, Morotti R, Nadal A, Navarro A, Nelander M, Oviedo A, Oyamada Otani AR, Papadogiannakis N, Petersen AC, Roberts DJ, Saad AG, Sand A, Schoenmakers S, Sehn JK, Simpson PR, Thomas K, Valdespino-Vázquez MY, van der Meeren LE, Van Dorpe J, Verdijk RM, Watkins JC, Zaigham M. Placental Tissue Destruction and Insufficiency from COVID-19 Causes Stillbirth and Neonatal Death from Hypoxic-Ischemic Injury: A Study of 68 Cases with SARS-CoV-2 Placentitis from 12 Countries. Arch Pathol Lab Med. 2022 Feb 10. doi: 10.5858/arpa.2022-0029-SA. Epub ahead of print. PMID: 35142798.

Study 926 – case report from USA

A 34-year-old woman with 3 prior live births, BMI 47.5 and chronic hypertension and a history of preeclampsia was hospitalized at 25 weeks of gestation for preeclampsia management (click here or study). She was asymptomatic but tested positive. Delivered at 25w+5d by Caesarean. It is not possible to identify the centre from author affiliations. Citation: Reagan-Steiner S, Bhatnagar J, Martines RB, Milligan NS, Gisondo C, Williams FB, Lee E, Estetter L, Bullock H, Goldsmith CS, Fair P, Hand J, Richardson G, Woodworth KR, Oduyebo T, Galang RR, Phillips R, Belyaeva E, Yin XM, Meaney-Delman D, Uyeki TM, Roberts DJ, Zaki SR. Detection of SARS-CoV-2 in Neonatal Autopsy Tissues and Placenta. Emerg Infect Dis. 2022 Feb 9;28(3). doi: 10.3201/eid2803.211735. Epub ahead of print. PMID: 35138244.

Study 925 – 26 cases from Iraq

Cared for at Al Yarmouk teaching hospital, Baghdad from June to August 2020 (click here or study) [abstract only]. Likely overlap with study 837. Citation: Hameed BH, Thamir AR, Jassim H, Hassan Ali MA. Maternal and perinatal outcome of pregnant women with COVID 19, a tertiary centre experience in Iraq – A Case Series. J Pak Med Assoc. 2021 Dec;71(Suppl 8)(12):S174-S178. PMID: 35130244.

Study 924 – case report from Italy

A 35-year-old woman pregnant with twins following IVF, and following cerclage at 16 weeks, ruptured her membranes at 20 weeks. She was asymptomatic but tested positive for SARS-Cov-2. The babies were stillborn at 21.4 weeks (click here or study). From author affiliations cared for at Papa Giovanni XXIII – Bergamo. The date of delivery is not reported so previous inclusion in the various Lombardy series is possible. Citation: L Patane , M Cadamuro , G Massazza , S Pirola , V Stagnati, C Comerio , M Carnelli , M Arosio , AP Callegaro , P Tebaldi , E Rigoli , A Gianatti , D Morotti, Evidence of vertical transmission of SARS-CoV-2 and interstitial pneumonia in second trimester twin stillbirth in asymptomatic woman. Case report and review of the literature, American Journal of Obstetrics & Gynecology MFM (2022), doi: https://doi.org/10.1016/j.ajogmf.2022.100589

Study 923 – 41 cases treated with remdesivir from USA

From author affiliations cared for at Ohio State University, Columbus, Ohio, from April 2020 through October 2021 (click here or study). This hospital does not appear to have previously reported cases. Citation: Eid J, Abdelwahab M, Colburn N, Day S, Cackovic M, Rood KM, Costantine MM. Early Administration of Remdesivir and Intensive Care Unit Admission in Hospitalized Pregnant Individuals With Coronavirus Disease 2019 (COVID-19). Obstet Gynecol. 2022 Feb 8. doi: 10.1097/AOG.0000000000004734. Epub ahead of print. PMID: 35134032.

Study 922 – 153 cases from Switzerland

Cared for in University Hospital of Bern, Lausanne University Hospital, and Ente Ospedaliero Cantonale Lugano, between May 2020 and July 2021 (click here or study). Possible overlap with studies 72, 310, 526 and 752. Citation: Radan A-P, Baud D, Favre G, Papadia A, Surbek D, Baumann M, Raio L, Low placental weight and altered metabolic scaling after severe acute respiratory syndrome coronavirus type 2 infection during pregnancy: a prospective multicentric study, Clinical Microbiology and Infection, https://doi.org/10.1016/j.cmi.2022.02.003.

Update 8 February – study 921 added

Study 921 – 2,352 cases from USA

From 17 hospitals participating in the Eunice Kennedy Shriver National Institute of Child Health and Human Development’s Gestational Research Assessments of COVID-19 (GRAVID) Study and delivered between March 1 and December 31, 2020 (click here or study). Likely overlap with studies 609 and 903 as well as other US studies. Citation: Metz TD, Clifton RG, Hughes BL, Sandoval GJ, Grobman WA, Saade GR, Manuck TA, Longo M, Sowles A, Clark K, Simhan HN, Rouse DJ, Mendez-Figueroa H, Gyamfi-Bannerman C, Bailit JL, Costantine MM, Sehdev HM, Tita ATN, Macones GA; National Institute of Child Health and Human Development Maternal-Fetal Medicine Units (MFMU) Network. Association of SARS-CoV-2 Infection With Serious Maternal Morbidity and Mortality From Obstetric Complications. JAMA. 2022 Feb 7. doi: 10.1001/jama.2022.1190. Epub ahead of print. PMID: 35129581. [control group]

Update 7 February – study 920 added

Study 920 – 8 cases from Northern Ireland

Collected during the Delta era of the pandemic from July to October 2021 (click here or study). Hospitals not reported. Citation: Graham, M., Sproule, C., Sharma, M., Likinyo, H., Glackin, K., Hurrell, D., Khalil, A. and Mone, F. (2022), Spontaneous maternal coagulopathy in COVID-19. Ultrasound Obstet Gynecol. Accepted Author Manuscript. https://doi.org/10.1002/uog.24859

Update 6 February – studies 915 to 919 added

Study 919 – 31 cases from China

Cared for at Zhongnan Hospital of Wuhan University, between January 2020 and Jnauary 2021 (click here or study). Likely overlap with many previous reports. Citation: Liu HY, Guo J, Zeng C, Cao Y, Ran R, Wu T, Yang G, Zhao D, Yang P, Yu X, Zhang W, Liu SM, Zhang Y. Transient Early Fine Motor Abnormalities in Infants Born to COVID-19 Mothers Are Associated With Placental Hypoxia and Ischemia. Front Pediatr. 2022 Jan 6;9:793561. doi: 10.3389/fped.2021.793561. PMID: 35071136; PMCID: PMC8772397.

Study 918 – 16 cases from Iran

Cared for at Imam Reza Hospital, Mashhad, from March 20 to August 5, 2020 (click here or study). Possible overlap with studies 101 and 250. Citation: Dadgar S, Mahmoudinia M, Akbari A, Zandieh E, Attaranzadeh A, Hoseinpour S, Jahanpak N, Tavanaee Sani A, Mohammadi SA. Placental infection with SARS-CoV-2, analysis of 16 cases and literature review. Arch Gynecol Obstet. 2022 Jan 28:1–9. doi: 10.1007/s00404-021-06372-5. Epub ahead of print. PMID: 35088195; PMCID: PMC8794612.

Study 917 – 16 cases from USA

Mother-infant dyads enrolled at Boston Medical Center between July 2020 and April 2021 (click here or study). Likely overlap with studies 292, 490, 681 and 684. Citation: Taglauer ES, Wachman EM, Juttukonda L, Klouda T, Kim J, Wang Q, Ishiyama A, Hackam DJ, Yuan K, Jia H. Acute Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Pregnancy Is Associated with Placental Angiotensin-Converting Enzyme 2 Shedding. Am J Pathol. 2022 Jan 26:S0002-9440(22)00011-6. doi: 10.1016/j.ajpath.2021.12.011. Epub ahead of print. PMID: 35090860; PMCID: PMC8789383.

Study 916 – 9 cases from Mexico

Cared for in Bíte Médica Hospital, Mexico City, which has not previously reported cases, in 2020 (click here or study). Citation: Vargas-Hernández VM, Luján-Irastorza JE, Durand-Montaño C. Placental pathology and perinatal risk during the COVID-19 pandemic. Gac Med Mex. 2021;157(5):494-501. English. doi: 10.24875/GMM.M21000604. PMID: 35104270.

Study 915 – 5 cases from Brazil

From Julio Muller University Hospital, Cuiabá, Mato Grosso, from June to July 2020 (click here or study). This hospital has not previously reported cases. Citation: Ferreira MFC, Pavon JAR, Napoleão ACB, Figueiredo GMDP, Florêncio PCB, Arantes RBDS, Rizzo PS, Carmo MAMV, Nakazato L, Dutra V, Hahn RC, Slhessarenko RD. Clinical and genomic data of sars-cov-2 detected in maternal-fetal interface during the first wave of infection in brazil. Microbes Infect. 2022 Feb 2:104949. doi: 10.1016/j.micinf.2022.104949. Epub ahead of print. PMID: 35123044.

Update 2 February – studies 911 to 914 added

Study 914 – 786 cases from Italy

From ITOSS between February 25 and August 31, 2020 (click here or study). Likely overlap with studies 246, 536, 674 and 862, as well as other Italian series. Citation: Donati S, Corsi E, Maraschini A, Salvatore MA; ItOSS COVID-19 Working Group; ItOSS COVID-19 WORKING GROUP. The first SARS-CoV-2 wave among pregnant women in Italy: results from a prospective population-based study. Ann Ist Super Sanita. 2021 Oct-Dec;57(4):272-285. doi: 10.4415/ANN_21_04_02. PMID: 35076417.

Study 913 – case report from Jordan

Born by cesarean at 35 weeks to a SARS-CoV-2-positive mother (click here or study). Authors affiliated with the University of Jordan, Amman. Citation: El-Isa HZ, Khader OA, Khader M, Ashour BA, Azzam MI, Badran EF. Secondary Hemophagocytic Lymphohistiocytosis in a Neonate with SARS-CoV-2 Infection. Am J Case Rep. 2022 Jan 28;23:e934839. doi: 10.12659/AJCR.934839. PMID: 35087017.

Study 912 – 82 cases from France

From Tenon hospital, Paris, which appears to have not previously reported cases (click here or study). Citation: Kolanska K, Vasileva R, Lionnet F, Santin A, Jaudi S, Dabi Y, Chabbert-Buffet N, Daraï E, Bornes M. Sickle cell disease and COVID-19 in pregnant women. J Gynecol Obstet Hum Reprod. 2022 Jan 28:102328. doi: 10.1016/j.jogoh.2022.102328. Epub ahead of print. PMID: 35093595; PMCID: PMC8800150.

Study 911 – 116 cases from Austria

From the Clinic Ottakring, Vienna, which has not previously reported cases (click here or study). One mother died and one required ECMO. No babies died. Citation: Hall M, Hölbfer S, Endress D, Aicher G, Drechsel-Burkhard G, Maier B. One year into the SARS-CoV-2 pandemic: perinatal outcome and data on the transmission of 116 pregnant women. J Perinat Med. 2022 Feb 1. doi: 10.1515/jpm-2021-0271. Epub ahead of print. PMID: 35107227.

Update 28 January – studies 906 to 910 added

Study 910 – 30 cases treated with monoclonals from USA

From author affiliations treated with bamlanivimab, bamlanivimab/etesevimab, or casirivimab/imdevimab between December 2020 and October 2021 at Montefiore Medical Center, Albert Einstein College of Medicine, New York (click here or study). This hospital has not previously reported cases from this time period. Citation: CHANG MH, COWMAN K, GUO Y, BAO H, BERNSTEIN PS, GENDLINA I, NORI P, A real-world assessment of tolerability and treatment outcomes of COVID-19 monoclonal antibodies administered in pregnancy, American Journal of Obstetrics and Gynecology (2022), doi: https://doi.org/10.1016/j.ajog.2022.01.018.

Study 909 – poor correlation between testing and diagnostic coding in USA

In the OptumLabs® Data Warehouse (OLDW), 78,283 individuals had a pregnancy ending between 11 March 2020 and 31 January 2021. Of the 5,644 with information on COVID-19 testing, 736 had a record of COVID-19. Of these 380 (51.6%) had only a COVID-19 diagnosis, 140 (19.0%) had only a positive laboratory test, and 216 (29.3%) had both a positive test and a COVID-19 diagnosis (click here or study). Likely overlap with study 896. Citation: Regan AK, Arah OA, Sullivan SG. Performance of diagnostic coding and laboratory testing results to measure COVID-19 during pregnancy and associations with pregnancy outcomes. Paediatr Perinat Epidemiol. 2022 Jan 25. doi: 10.1111/ppe.12863. Epub ahead of print. PMID: 35077581.

Study 908 – 83 cases from Poland

Cared for between 15 February and 01 May 2021 at Wroclaw Medical University Teaching Hospital (click here or study). This hospital has not previously reported cases. Citation: Szczygiol P, Baranska K, Korczak I, Zimmer-Stelmach A, Rosner-Tenerowicz A, Zimmer M, Krolak-Olejnik B. COVID-19 in pregnancy, management and outcomes among pregnant women and neonates – results from tertiary care center in Wroclaw. Ginekol Pol. 2022 Jan 24. doi: 10.5603/GP.a2021.0201. Epub ahead of print. PMID: 35072251.

Study 907 – 122 cases from Turkey

Pregnant patients with confirmed COVID-19 from April 1 to May 31, 2020, at Kanuni Sultan Süleyman Training and Research Hospital, Istanbul (click here or study). This hospital has not previously reported cases. Citation Can E, Oğlak SC, Ölmez F. Abnormal liver function tests in pregnant patients with COVID-19 – a retrospective cohort study in a tertiary center. Ginekol Pol. 2022 Jan 24. doi: 10.5603/GP.a2021.0182. Epub ahead of print. PMID: 35072238.

Study 906 – vaccine status of 318 severe cases in Europe

Although labelled as a comment, the authors report the vaccination status of 318 pregnant women admitted to critical care with covid fromMay-December 2021, and collected by the UKOSS, NethOSS registries and from Denmark, Finland, Norway and the Lombardy region of Italy (click here or study). The cases will likely overlap with many previous reports, but the vaccine status is original. Citation: Engjom, Hilde et al. Severe COVID-19 in pregnancy is almost exclusively limited to unvaccinated women – time for policies to change The Lancet Regional Health – Europe, Volume 13, 100313 [important]

Update 22 January – study 905 added belatedly

Study 905 – 4,203 cases from India

Collected by the PregCovid registry from 19 medical colleges across the State of Maharashtra during the first wave (March 2020-January 2021) (click here or study). Likely overlap with studies 225, 283, 369, 501, 520, 547, 746, 777, 778, 839 and 840. Citation: Gajbhiye RK, Mahajan NN, Waghmare RB, Zala S, Chaaithanya IK, Kuppusamy P, Bhurke AV, Pious M, Surve S, Modi DN, Mahale SD; PregCovid Registry Network. Clinical characteristics, outcomes, & mortality in pregnant women with COVID-19 in Maharashtra, India: Results from PregCovid registry. Indian J Med Res. 2021 May;153(5&6):629-636. doi: 10.4103/ijmr.ijmr_1938_21. PMID: 34596595; PMCID: PMC8555584.

Update 20 January – study 904 added

Study 904 – 882 cases from USA

882 pregnant women who tested positive (1st trimester 85; 2nd 226; 3rd 571) out of 73,666 who delivered at Providence St Joseph Health sites in Alaska, California, Montana, Oregon, or Washington between March 5, 2020, and July 4, 2021 (click here or study). Citation: Samantha N Piekos, Ryan T Roper, Yeon Mi Hwang, Tanya Sorensen, Nathan D Price, Leroy Hood, Jennifer J Hadlock. The effect of maternal SARS-CoV-2 infection timing on birth outcomes: a retrospective multicentre cohort study. Lancet Digit Health 2021 Published Online January 13, 2022 https://doi.org/10.1016/S2589-7500(21)00250-8

Update 19 January – study 903 added

Study 903 – 12 cases from USA

Lab studies on stored samples from the Eunice Kennedy Shriver NICHHD from Bethesda, Maryland, and Detroit, Michigan (click here or study) Clinical data reported in Supplementary table 1 (click here or suppl table). Likely overlap with previous US reports. Citation: Garcia-Flores, V., Romero, R., Xu, Y. et al. Maternal-fetal immune responses in pregnant women infected with SARS-CoV-2. Nat Commun 13, 320 (2022). https://doi.org/10.1038/s41467-021-27745-z

Update 13 January – Studies 901 and 902 added. Study 884 updated.

Study 902 – 3 cases from USA

From the COVID-19 in Pregnancy Biorepository, approved by the Mass General Brigham Institutional Review Board, and cared for in August 2021 at Massachusetts General Hospital (click here or study). Overlap with study 856, and other reports from this biorepository, is unlikely, due to birth timing and clinical features. Citation: Lydia L Shook, MD, Sara Brigida, BA, James Regan, BS, James P Flynn, BS, Abbas Mohammadi, MD, Behzad Etemad, PhD, Molly R Siegel, MD, Mark A Clapp, MD, MPH, Jonathan Z Li, MD, Drucilla J Roberts, MD, Andrea G Edlow, MD MSc, SARS-CoV-2 placentitis associated with B.1.617.2 (Delta) variant and fetal distress or demise, The Journal of Infectious Diseases, 2022;, jiac008, https://doi.org/10.1093/infdis/jiac008

Study 901 – 7 cases from Ireland

Seven women with Covid who experienced second trimester miscarriage, stillbirth or neonatal death during the first three months of 2021 (click here or study). Citation: Fitzgerald B, O’Donoghue K, McEntagart N, Gillan JE, Kelehan P, O’Leary J, Downey P, Dean J, De Gascun CF, Bermingham J, Armstrong F, Al Fathil A, Maher N, Murphy C, Burke L. Fetal deaths in Ireland due to SARS-CoV-2 placentitis caused by SARS-CoV-2 Alpha. Arch Pathol Lab Med. 2022 Jan 12. doi: 10.5858/arpa.2021-0586-SA. Epub ahead of print. PMID: 35020786.

Update 12 January – study 900 added

Study 900 – 306 cases from USA

From the Ochsner Health System between June 15 and August 20, 2021 (click here or study). Citation: Morgan JA, Biggio JR Jr, Martin JK, Mussarat N, Chawla HK, Puri P, Williams FB. Maternal Outcomes After Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Vaccinated Compared With Unvaccinated Pregnant Patients. Obstet Gynecol. 2022 Jan 1;139(1):107-109. doi: 10.1097/AOG.0000000000004621. PMID: 34644272.

Update 11 January – studies 898 and 899 added

Study 899 – case report from Italy

From Universitario Agostino Gemelli IRCCS, Rome (click here or study). Possibly included in study 76 and may be the same case as study 78. Likely also included in some other series from Italy. Citation: Costa S, Delogu AB, Bottoni A, Purcaro V, D’Andrea V, Paladini A, Muto S, Marano R, Savino G, Secinaro A, De Benedetti F, Carsetti R, Piano Mortari E, Spanu T, Vento G. COVID-19 associated multisystem inflammatory syndrome in a neonate with atypical coronary artery involvement. Am J Perinatol. 2022 Jan 7. doi: 10.1055/a-1733-4163. Epub ahead of print. PMID: 34996119.

Study 898 – Affected mother with triplets in Germany

From the Women’s Hospital, Weiden which has not previously reported cases (click here or study). Citation: Disse SC, Manuylova T, Adam K, Lechler A, Zant R, Klingel K, Aepinus C, Finkenzeller T, Wellmann S, Schneble F. COVID-19 in 28-Week Triplets Caused by Intrauterine Transmission of SARS-CoV-2-Case Report. Front Pediatr. 2021 Dec 24;9:812057. doi: 10.3389/fped.2021.812057. PMID: 35004553; PMCID: PMC8740284.

Update 7 January – studies 896 & 897 added. Inadvertent study number duplication of studies 847 to 863 corrected, with later duplicates renumbered as 847b to 863b

Study 897 – 33 cases from Pakistan

Cared for in the HDU or ITU at Sir Sadiq Abbasi Hospital, Bahawalpur from 15th August to 15th September, 2021 (click here or study). Eight mothers died. This hospital has not previously reported cases. Citation: Aslam J, Masroor M, Mehmood QUA, Arshad M, Jabeen S, Mushtaq MA. Maternal Mortality with SARS-COV-2 during its 4th Wave in Pakistan: The Vaccine Paradox and Pregnancy. J Coll Physicians Surg Pak 2022; 32(01):119-121.

Study 896 – 25 pregnant women in ICU in Ireland

Admitted to ICU during wave four, 27 June to 25 December 2021 (click here or study). Overlap with study 858. Citation: Intensive Care Society of Ireland. Epidemiology of intensive care admissions in cases (aged 15 years and older) of COVID-19 in Ireland Report prepared by HPSC on 29.12.2021 https://www.hpsc.ie/a-z/respiratory/coronavirus/novelcoronavirus/surveillance/covid-19intensivecareadmissions/COVID-19_ICU_Report_Adults_29_12_2021_v0.1_website.pdf Accessed 7 January 2022

Update 2 January – studies 892 to 895 added

Study 895 – 725 cases from the Intercovid registry

(click here or study). Previously reported in studies 683 and 737 Citation: Eskenazi B, Rauch S, Iurlaro E, Gunier RB, Rego A, Gravett MG, Cavoretto PI, Deruelle P, García-May PK, Mhatre M, Usman MA, Elbahnasawy M, Etuk Fwacs S, Napolitano R, Deantoni S, Liu B, Prefumo F, Savasi V, Marques PF, Baafi E, Zainab G, Nieto R, Serrano B, Aminu MB, Cardona-Perez JA, Craik R, Winsey A, Tavchioska G, Bako B, Oros D, Benski C, Galadanci H, Savorani M, Oberto M, Sentilhes L, Risso M, Takahashi K, Vecciarelli C, Ikenoue S, Pandey AK, Soto Conti CP, Cetin I, Nachinab VB, Ernawati E, Duro EA, Kholin A, Firlit ML, Easter SR, Sichitiu J, John-Akinola Y, Casale R, Cena H, Agyeman-Duah J, Roggero P, Langer A, Bhutta ZA, Kennedy SH, Villar J, Papageorghiou AT. Diabetes mellitus, maternal adiposity, and insulin-dependent gestational diabetes are associated with Covid-19 in pregnancy: The INTERCOVID Study. Am J Obstet Gynecol. 2021 Dec 20:S0002-9378(21)02696-X. doi: 10.1016/j.ajog.2021.12.032. Epub ahead of print. PMID: 34942154; PMCID: PMC8686449.

Study 894 – 100 cases from South Africa

Cared for at Tygerberg Hospital, Cape Town, from 1 May to 31 July 2020 (click here or study). This hospital has not previously reported cases. Citation: De Waard L, Langenegger E, Erasmus K, Van der Merwe T, Olivier SE, Du Toit N, Paulsen C, Nkangana N, Van Niekerk M, Moodley A, Schell S, Taljaard J, Botha MH, Dramowski A, Cluver CA, Bekker A. Maternal and neonatal outcomes of COVID-19 in a high-risk pregnant cohort with and without HIV. S Afr Med J. 2021 Dec 2;111(12):1174-1180. doi: 10.7196/SAMJ.2021.v111i12.15683. PMID: 34949304.

Study 893 – Two pregnancy cases treated with monoclonal antibody from USA

From Cedars-Sinai Medical Center, Los Angeles, California (click here or study). Citation: Mayer C, VanHise K, Caskey R, Naqvi M, Burwick RM. Monoclonal Antibodies Casirivimab and Imdevimab in Pregnancy for Coronavirus Disease 2019 (COVID-19). Obstet Gynecol. 2021 Dec 1;138(6):937-939. doi: 10.1097/AOG.0000000000004603. PMID: 34583385.

Study 892 – 51 pregnancy cases treated with monoclonal antibody from USA

Collected by the Mayo Clinic Monoclonal Antibody Treatment (MATRx) Program and treated between November 19, 2020 and September 23, 2021 (click here or study). Citation: Bright P. Thilagar, Aditya K. Ghosh, Jerome Nguyen, Regan N. Theiler, Myra J. Wick, Ryan T. Hurt, Raymund R. Razonable, Ravindra Ganesh. Outcomes of Anti-Spike Monoclonal Antibody Therapy in Pregnant Women with Mild to Moderate COVID-19. medRxiv 2021.11.27.21266942; doi: https://doi.org/10.1101/2021.11.27.21266942

Update 1 Jan 2022 – study 891 added

Study 891 – 4 cases from Turkey

From Etlik Zübeyde Hanım Women’s Health Care, Training and Research Hospital, Ankara, which has not previously reported cases (click here or study). Citation: Yucel Celik O, Çelen Ş, Engin Üstün Y. Did the SARS-CoV-2 effect pregnancy complications? Ginekol Pol. 2021 Jul 15. doi: 10.5603/GP.a2021.0134. Epub ahead of print. PMID: 34263916.

Update 31 December – study 890 added

Study 890 – Ten cases from USA

From Saint Francis Hospital and Medical Center, of Trinity Health of New England, Hartford, Connecticut from April 24 to May 21, 2020 (click here or study). This hospital has not previously reported cases. Citation: Pimentel VM, Jackson FI, Ferrante AD, Figueroa R. Ethnic Disparities in Coronavirus Disease 2019 after the Implementation of Universal Screening in Hartford, Connecticut. AJP Rep. 2021 Dec 22;11(4):e147-e153. doi: 10.1055/s-0041-1740562. PMID: 34966566; PMCID: PMC8695059.

Update 29 December – studies 894 to 899 added, and study 882 updated

Study 899 – 8 cases from USA

From the MotherToBaby prospective cohort collected by the OTIS Research Center at University California, San Diego (click here or study). This appears to be the first Covid report from this cohort, but overlap with other cases from California is possible. Citation: Hsieh LE, Grifoni A, Dave H, Wang J, Johnson D, Zellner J, Sidney J, Chambers C, Franco A. SARS-CoV-2-specific T cell responses and immune regulation in infected pregnant women. J Reprod Immunol. 2021 Dec 11;149:103464. doi: 10.1016/j.jri.2021.103464. Epub ahead of print. PMID: 34953325; PMCID: PMC8665650.

Study 898 – 87 cases from Oman, Iraq & Jordan

Abstract only available (click here or study). Citation: Al Hashmi I, Khalaf A, Seshan V, Alsabti H, Al Omari O, Yehia D, Baqer M, Al Khadhuri J. Maternal and Neonatal Outcomes of Healthy Pregnant Women With COVID-19 Versus High-risk Pregnant Women: A Multi-Center Case-Control Comparison Study. Clin Nurs Res. 2021 Dec 26:10547738211064027. doi: 10.1177/10547738211064027. Epub ahead of print. PMID: 34955040.

Study 897 – case report from Oman

From Sultan Qaboos University Hospital, Al Khod, Muscat, which has not previously reported cases (click here or study). Citation: Burad J, Kodange S. Neuroleptic Malignant Syndrome due to Atypical Antipsychotics in a COVID-19-positive Pregnant Woman. Indian J Crit Care Med. 2021 Sep;25(9):1073-1074. doi: 10.5005/jp-journals-10071-23959. PMID: 34963731; PMCID: PMC8664039.

Study 896 – 2,655 cases from USA

Using claims data from the OptumLabs Data Warehouse (click here or study). This stores deidentified patient data from all over the US. Likely overlap with many other series. Citation: Regan AK, Arah O, Fell DB, Sullivan SG. SARS-CoV-2 infection during pregnancy and associated perinatal health outcomes: a national US cohort study. J Infect Dis. 2021 Dec 27:jiab626. doi: 10.1093/infdis/jiab626. Epub ahead of print. PMID: 34958090.

Study 895 – 57 cases from Italy

From author affiliations cared for between April 2020 to October 2021 at San Gerardo Hospital, Monza, so likely overlap with studies 64, 117, 252, and 709 as well as the various Lombary series (click here or study). Citation: Giardini V, Ornaghi S, Acampora E, Vasarri MV, Arienti F, Gambacorti-Passerini C, Casati M, Carrer A, Vergani P. Letter to the Editor: SFlt-1 and PlGF Levels in Pregnancies Complicated by SARS-CoV-2 Infection. Viruses. 2021 Nov 27;13(12):2377. doi: 10.3390/v13122377. PMID: 34960646.

Study 894 – case report from Slovakia

From author affiliations cared for at University Hospital, Trnava, which has not previously reported cases (click here or study). Citation: Babal P, Krivosikova L, Sarvaicova L, Deckov I, Szemes T, Sedlackova T, Palkovic M, Kalinakova A, Janega P. Intrauterine Fetal Demise After Uncomplicated COVID-19: What Can We Learn from the Case? Viruses. 2021 Dec 19;13(12):2545. doi: 10.3390/v13122545. PMID: 34960815.

Update 24 December – study 893 added

Study 893 – 427 cases from USA

From six Northwell Health hospitals and Maimonides Medical Center, New York between April 10th and June 4th 2020 (click here or study). Probable overlap with studies 113, 134, 162, 179, 289, 315, 331, 561 & 854. Citation: London V, Blitz MJ, Solmonovich R, Silver M, Minkoff H. Temporal Trend in SARS-CoV-2 Symptoms in Pregnant Women. Am J Perinatol. 2021 Dec 16. doi: 10.1055/s-0041-1739490. Epub ahead of print. PMID: 34918329.

Update 23 December – studies 887 to 892 added

Study 892 – 7 cases from Nigeria

Cared for at University of Port Harcourt Teaching Hospital, Rivers State, from March to August 2020 (abstract click here or study). This centre has not previously reported cases. Citation: Alasia D, Maduka O, Oputa VO, Orazulike N, Otokwala J, Osemwegie N, Ozah C, Inya JN, Omietimi S, Ogan S, Ugboma H, Stanley P. COVID-19 and Pregnancy: A Prospective Descriptive Study from a Tertiary Hospital in Nigeria. West Afr J Med. 2021 Nov 30;Vol. 38(11):1036-1041. PMID: 34919179.

Study 891 – 856 cases from India

Cared for at the Government Medical College, Kannur, Kerala, from 1 August 2020 to 31 July 2021 (click here or study). Likely overlap with study 618 (not cited). Citation: Kurian S, Mathews M, Reshmi VP, Divakaran B, Ajith S. Impact of diabetes on the severity of COVID-19 infection in pregnant women – A single-center descriptive study. Diabetes Metab Syndr. 2021 Dec 9;16(1):102362. doi: 10.1016/j.dsx.2021.102362. Epub ahead of print. PMID: 34922215; PMCID: PMC8654463.

Study 890 – 5 cases treated with ECMO in USA

Cared for at University of California, Los Angeles from March 2020 to August 2021 (click here or study). Two cases previously included in study 323. Citation: Yin O, Richley M, Hadaya J, Mei J, Mok T, Fahim M, Pluym ID, Rao R, Martin C, Han CS, Benharesh P, Afshar Y, Extracorporeal membrane oxygenation in pregnancy: a bridge to delivery and pulmonary recovery for COVID-19-related severe respiratory failure, American Journal of Obstetrics and Gynecology (2022), doi: https://doi.org/10.1016/j.ajog.2021.12.024.

Study 889 – 9 cases from China

Cared for in Wuhan Maternal and Child Health Hospital from January 24 to March 14, 2020 (click here or study). Likely reported many times. Citation: Cheng Y, Teng H, Xiao Y, Yao M, Yin J, Sun G. Impact of SARS-CoV-2 Infection During Pregnancy on Infant Neurobehavioral Development: A Case-Control Study. Front Pediatr. 2021 Dec 2;9:762684. doi: 10.3389/fped.2021.762684. PMID: 34926345; PMCID: PMC8678601.

Study 888 – 6,073 cases from Brazil

Data from SIVEP-Gripe (Sistema de Informação de Vigilância Epidemiológica da Gripe), a nationwide database severe acute respiratory syndrome (SARS), from February 2020 until May 1, 2021 (click here or study). Likely overlap with many other series from Brazil. Citation: Gonçalves BMM, Franco RPV, Rodrigues AS. Maternal mortality associated with COVID-19 in Brazil in 2020 and 2021: Comparison with non-pregnant women and men. PLoS One. 2021 Dec 21;16(12):e0261492. doi: 10.1371/journal.pone.0261492. PMID: 34932589.

Study 887 – case report from Iran

From Alborz University of Medical Sciences, Karaj (click here or study). The clinical details differ from those reported in study 584. Citation: Farahani M, Azadi K, Hashemnejad M, Agoushi A, Nirouei M. Ruled out of preeclampsia-like syndrome due to COVID-19: A case study. Clin Case Rep. 2021 Dec 7;9(12):e05195. doi: 10.1002/ccr3.5195. PMID: 34934502; PMCID: PMC8650748.

Update 17 December – studies 884 to 886 added

Study 886 – 151,354 cases from USA

13 December update of CDC surveillance includes 249 maternal deaths (click here or data). Citation: Centres for Disease Control. Weekly COVID-19 Pregnancy Data updated 13 December 2021, Accessed 17 December 2021.

Study 885 – 1,436 cases from UK

This infographic from the UKOSS team reports cases admitted to hospital for the delta predominant period, 16th May to 31st October 2021 (click here or study). It also shows that from the start of the pandemic up to 31 October, 34 pregnant or postnatal women had died with Covid in UK. Note different denominator periods. Overlap with previous UKOSS reports, especially study 846. Citation: Knight M. UKOSS infographic. 16 December 2021. Accessed 17 December 2021

Study 884 – 4,274 cases from Scotland

National data up to to September 30, 2021 (click here or study). No maternal deaths. Perinatal mortality 9/567 births within 28 days of diagnosis (PMR 15.9/1000; 95% CI 7.8 to 31.0). All perinatal deaths in unvaccinated women. Citation: Sarah Stock, Jade Carruthers, Clara Calvert et al. COVID-19 vaccination rates and SARS-CoV-2 infection in pregnant women in Scotland, 09 November 2021, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-1051010/v1] Update 13 Jan 2022 Peer reviewed version (click here or study). Citation: Stock, S.J., Carruthers, J., Calvert, C. et al. SARS-CoV-2 infection and COVID-19 vaccination rates in pregnant women in Scotland. Nat Med (2022). https://doi.org/10.1038/s41591-021-01666-2

Update 13 December – studies 882 and 883 added

Study 883 – 9,620 cases from The Netherlands

We’ve not reported on the NETHOSS registry recently. On 7 December it included 9,620 pregnant women with a proven COVID-19 infection, between 1 March 2020 to 1 May 2021 (click here or study). Citation: NETHOSS registry. https://www-nvog-nl.translate.goog/actueel/registratie-van-covid-19-positieve-zwangeren-in-nethoss/?_x_tr_sl=nl&_x_tr_tl=en&_x_tr_hl=en-GB&_x_tr_pto=op,sc Accessed 13 Dec 2021.

Study 882 – 112 cases from USA

Cared for at at Thomas Jefferson University Hospital from April 2020-February 2021 (click here or study). Possible overlap with studies 65, 86 and 359. Citation: Rupsa C. Boelig, Sidhartha Chaudhury, Zubair H. Aghai, Emily Oliver, Francesca Manusco, Vincenzo Berghella, Elke Bergmann-Leitner. Comprehensive Serological Profile and Specificity of Maternal and Neonatal Cord Blood SARS CoV-2 Antibodies. medRxiv 2021.12.06.21267328; doi: https://doi.org/10.1101/2021.12.06.21267328 Update 29 December Peer review publication (click here or study). Citation: Boelig RC, Chaudhury S, Aghai ZH, Oliver E, Manusco F, Berghella V, Bergmann-Leitner E. Comprehensive Serological Profile and Specificity of Maternal and Neonatal Cord Blood SARS CoV-2 Antibodies. AJOG Glob Rep. 2021 Dec 23:100046. doi: 10.1016/j.xagr.2021.100046. Epub ahead of print. PMID: 34961853; PMCID: PMC8697419.

Update 10 December – studies 877 to 881 added

Study 881 – 4 cases treated with monoclonal antibodies from USA

From author affiliations probably treated in Barnes-Jewish Hospital, in St. Louis, Missouri, between November 2020 and July 2021 (click here or study). They may have been included in studies 259, 290, 579 and 638. Citation: Hirshberg JS, Cooke E, Oakes MC, Odibo AO, Raghuraman N, Kelly JC. Monoclonal antibody treatment of symptomatic COVID-19 in pregnancy: initial report. Am J Obstet Gynecol. 2021 Dec;225(6):688-689. doi: 10.1016/j.ajog.2021.08.025. Epub 2021 Aug 25. PMID: 34453934; PMCID: PMC8386136.

Study 880 – 70 cases from Bangladesh

From Dhaka, Sir Salimullah, and Mugdha, Medical College & Hospitals, all three in Dhaka, between March and August 2020 (click here or study). Citation: Binte Masud S, Zebeen F, Alam DW, Hossian M, Zaman S, Begum RA, Nabi MH, Hawlader MDH. Adverse Birth Outcomes Among Pregnant Women With and Without COVID-19: A Comparative Study From Bangladesh. J Prev Med Public Health. 2021 Nov;54(6):422-430. doi: 10.3961/jpmph.21.432. Epub 2021 Oct 21. PMID: 34875825.

Study 879 – 60 cases from India

From the All India Institute of Medical Sciences, Rishikesh, which has not previously reported cases, from July to December 2020 (click here or study). Citation: Khoiwal K, Agarwal A, Gaurav A, Kumari R, Mittal A, Sabnani S, Mundhra R, Chawla L, Bahadur A, Chaturvedi J. Obstetric and perinatal outcomes in pregnant women with COVID-19: an interim analysis. Women Health. 2021 Dec 7:1-9. doi: 10.1080/03630242.2021.2007199. Epub ahead of print. PMID: 34875976.

Study 878 – 193 cases from Slovenia

From University Medical Center, Ljubljana between October 27th 2020 and January 31st 2021 (click here or study). Probably a different hospital as study 393, and certainly a later time period. Citation: Lucovnik M, Druskovic M, Vidmar Simic M, Verdenik I, Mesaric V, Kosir R, Kornhauser Cerar L, Tojner Bregar A, Steblovnik L, Kavsek G, Premru Srsen T. Perinatal outcomes in women with severe acute respiratory syndrome coronavirus 2 infection: comparison with contemporary and matched pre-COVID-19 controls. J Perinat Med. 2021 Dec 9. doi: 10.1515/jpm-2021-0313. Epub ahead of print. PMID: 34881547.

Study 877 – 33 cases from USA

From Prentice Women’s Hospital and Erie Family Health Center in Illinois between 3 April and 26 July 2020 (click here or study). Neither centre has previously reported cases. Citation: Schuh TL, Mithal LB, Naureckas S, Miller ES, Garfield CF, Shah MD. Outcomes from birth to 6 months of publicly insured infants born to mothers with severe acute respiratory syndrome coronavirus 2 infection in the United States. J Perinat Med. 2021 Dec 10. doi: 10.1515/jpm-2021-0251. Epub ahead of print. PMID: 34882359.

Update 1 December – study 876 added

Study 876 – 874 cases from France

From the French national hospitalization database (PMSI) between January and June 202 (click here or study). Likely includes cases from many previous French series. Citation: Epelboin S, Labrosse J, De Mouzon J, Fauque P, Gervoise-Boyer MJ, Levy R, Sermondade N, Hesters L, Bergère M, Devienne C, Jonveaux P, Ghosn J, Pessione F. Obstetrical outcomes and maternal morbidities associated with COVID-19 in pregnant women in France: A national retrospective cohort study. PLoS Med. 2021 Nov 30;18(11):e1003857. doi: 10.1371/journal.pmed.1003857. PMID: 34847147.

Update 30 November – studies 872 to 875 added

Study 875 – some cases from Israel

Neither full text nor abstract available yet (click here or study). Citation: Ganor Paz Y, Shiloh S, Brosh-Nissimov T, Grupel D, Sorek N, Kustin T, Stern A, Maklakovsky M, Polak M, Sharvit M, Neeman O, Ben Valid T, Tovbin J, Barzilay E. The association between SARS-CoV-2 infection and late pregnancy loss. Int J Gynaecol Obstet. 2021 Nov 14. doi: 10.1002/ijgo.14025. Epub ahead of print. PMID: 34778964.

Study 874 – 52 cases from Poland

From the Central Clinical Hospital of the Ministry of the Interior and Administration, in Warsaw, which has not previously reported cases (click here or study). Citation: Januszewski M, Ziuzia-Januszewska L, Jakimiuk AA, Wierzba W, Gluszko A, Zytynska-Daniluk J, Jakimiuk AJ. Is the Course of COVID-19 Different during Pregnancy? A Retrospective Comparative Study. Int J Environ Res Public Health. 2021 Nov 16;18(22):12011. doi: 10.3390/ijerph182212011. PMID: 34831766; PMCID: PMC8620897.

Study 873 – 1,704 cases from Spain

From the 79 hospitals of the Spanish Obstetric Emergency Group between 26 February and 5 November 2020 (click here or study). Likely overlap with studies 264b, 712, 727, 740 and 849 and perhaps others. Citation: Morán Antolín E, Broullón Molanes JR, de la Cruz Conty ML, Encinas Pardilla MB, Guadix Martín MDP, Sainz Bueno JA, Forcén Acebal L, Pintado Recarte P, Álvarez Bartolomé A, Martínez Cendán JP, Martínez-Pérez Ó, On Behalf Of The Spanish Obstetric Emergency Group. SARS-CoV-2 Infection and C-Section: A Prospective Observational Study. Viruses. 2021 Nov 22;13(11):2330. doi: 10.3390/v13112330. PMID: 34835136; PMCID: PMC8622813.

Study 872 – 110 cases from Turkey

From Adana City Education and Research Hospital, which has not previously reported cases (click here or study). Citation: Arslan B, Bicer IG, Sahin T, Vay M, Dilek O, Destegul E. Clinical characteristics and hematological parameters associated with disease severity in COVID-19 positive pregnant women undergoing cesarean section: A single-center experience. J Obstet Gynaecol Res. 2021 Nov 27. doi: 10.1111/jog.15108. Epub ahead of print. PMID: 34837446.

Update 29 November – studies 868 to 871 added

Study 871 – 76 cases from Romania

From Timisoara Municipal Emergency Hospital between 1 July 2020 and 1 July 2021 (click here or study). This hospital has not previously reported cases. Citation: Citu C, Neamtu R, Sorop VB, Horhat DI, Gorun F, Tudorache E, Gorun OM, Boarta A, Tuta-Sas I, Citu IM. Assessing SARS-CoV-2 Vertical Transmission and Neonatal Complications. J Clin Med. 2021 Nov 11;10(22):5253. doi: 10.3390/jcm10225253. PMID: 34830532; PMCID: PMC8617726.

Study 870 – 13 cases from Angola

From Lucrécia Paim maternity hospital in Luanda, which has not previously reported cases (click here or study). Citation: Sebastião CS, Parimbelli P, Mendes M, Sacomboio E, Morais J, de Vasconcelos JN, Brito M. Prevalence and Risk Factors of SARS-CoV-2 Infection among Parturients and Newborns from Luanda, Angola. Pathogens. 2021 Nov 16;10(11):1494. doi: 10.3390/pathogens10111494. PMID: 34832649; PMCID: PMC8624220.

Study 869 – case report from Romania

From “Elena Doamna” Hospital, Iasi (click here or study). Citation: Socolov R, Akad M, Păvăleanu M, Popovici D, Ciuhodaru M, Covali R, Akad F, Păvăleanu I. The Rare Case of a COVID-19 Pregnant Patient with Quadruplets and Postpartum Severe Pneumonia. Case Report and Review of the Literature. Medicina (Kaunas). 2021 Nov 1;57(11):1186. doi: 10.3390/medicina57111186. PMID: 34833404; PMCID: PMC8624501.

Study 868 – 20 cases from Turkey

From Basaksehir Cam and Sakura City Hospital, Istanbul (click here or study). Likely overlap with study 770. Citation: Yasa B, Memur S, Ozturk DY, Bagci O, Uslu SI, Cetinkaya M. Neonatal Outcomes of Premature Infants Born to Women with the Novel Coronavirus (SARS-CoV-2) Infection: A Case Control Study. Am J Perinatol. 2021 Nov 28. doi: 10.1055/s-0041-1740177. Epub ahead of print. PMID: 34839474.

Update 26 November – studies 864 to 867 added

Study 867 – 458 cases from Turkey

From Ankara City Hospital (click here or study). No harmful effect on newborn hearing noted. Probable overlap with previous cases from that hospital. Citation: Oskovi-Kaplan ZA, Ozgu-Erdinc AS, Buyuk GN, Sert-Dinc UY, Ali-Algan C, Demir B, Sahin D, Keskin HL, Tayman C, Moraloglu-Tekin Ö. Newborn Hearing Screening Results of Infants Born To Mothers Who Had COVID-19 Disease During Pregnancy: A Retrospective Cohort Study. Ear Hear. 2021 Nov 19. doi: 10.1097/AUD.0000000000001167. Epub ahead of print. PMID: 34812792.

Study 866 – ten cases treated with ECMO from USA

Five pregnant and five postpartum women with Covid, treated at Baylor University Medical Center Dallas, Texas, and at Baylor Scott & White The Heart Hospital, Plano, Texas (click here or study). Six survived to discharge, two died, and two remain inpatients. Citation: Shih E, DiMaio JM, Squiers JJ, Krueger AR, Schwartz GS, Herd J, Bleich AT. Treatment of Acute Respiratory Distress Syndrome from COVID-19 with Extracorporeal Membrane Oxygenation in Obstetric Patients. Am J Obstet Gynecol MFM. 2021 Nov 20:100537. doi: 10.1016/j.ajogmf.2021.100537. Epub ahead of print. PMID: 34813975; PMCID: PMC8605810.

Study 865 – Seventeen 1st trimester cases from Italy

Cared for at an unnamed hospital in Turin between 16 April and 22 June 2020 (click here or study). Possible overlap with studies 167, 195, 247, 615, 644, and 775. Citation: Cosma S, Carosso AR, Cusato J, Borella F, Bertero L, Bovetti M, Bevilacqua F, Mengozzi G, Mazzone R, Ghisetti V, Di Perri G, Benedetto C. Obstetric and neonatal outcomes after SARS-CoV-2 infection in the first trimester of pregnancy: A prospective comparative study. J Obstet Gynaecol Res. 2021 Nov 23. doi: 10.1111/jog.15105. Epub ahead of print. PMID: 34814234.

Study 864 – 1,637 cases from USA

Collected by Mississippi State Department of Health between March 1, 2020 & October 6, 2021 (click here or study). Maternal mortality in the pre-delta period (5/1000 cases) rose to 25/1000 during the delta predominant period. Likely overlap with study 597. Citation: Kasehagen L, Byers P, Taylor K, et al. COVID-19–Associated Deaths After SARS-CoV-2 Infection During Pregnancy — Mississippi, March 1, 2020–October 6, 2021. MMWR Morb Mortal Wkly Rep 2021;70:1646–1648. DOI: http://dx.doi.org/10.15585/mmwr.mm7047e2

Update 23 November – study 863 added

Study 863b – follow up of 298 cases from Kuwait

Infants born between April 1 and August 30, 2020, to mothers with SARS-CoV-2 infection during various trimesters of pregnancy, identified from the Kuwait National COVID-19 registry (click here or study). Of 840 pregnant women with COVID-19, 445 gave birth, and 298 infants were followed up at one year. Likely overlap with study 189. Citation: Mariam Ayed, Alia Embaireeg, Mais Kartam, Kiran More, Mafaza Alqallaf, Abdullah AlNafisi, Zainab Alsaffar, Zainab Bahzad, Yasmeen Buhamad, Haneen Alsayegh, Wadha Al-Fouzan, Hessa Alkandari. Neurodevelopmental outcomes of infants secondary to in utero exposure to maternal SARS-CoV-2 infection: A national prospective study in Kuwait. medRxiv 2021.11.12.21266291; doi: https://doi.org/10.1101/2021.11.12.21266291Update 22 November – study 862 added

Study 862b – Delta variant stillbirths in USA

From the Premier Healthcare Database Special COVID-19 Release (PHD-SR) before and during the
period of Delta variant predominance in the United States (March 2020–June 2021 and July–September 2021, respectively) (click here or study). COVID-19 documented at delivery was associated with increased risk for stillbirth (aRR = 1.90; 95% CI = 1.69–2.15), with a stronger association during the period of Delta variant predominance (aRR = 4.04; 95% CI = 3.28–4.97). Citation: DeSisto CL, Wallace B, Simeone RM, et al. Risk for Stillbirth Among Women With and Without COVID-19 at Delivery Hospitalization — United States, March 2020–September 2021. MMWR Morb Mortal Wkly Rep. ePub: 19 November 2021. DOI: http://dx.doi.org/10.15585/mmwr.mm7047e1 [Important]

Update 18 November – studies 858 to 861 added

Study 861b – seven cases from USA

From the University of Arkansas for the Medical Sciences, Little Rock, Arkansas, which has not previously reported cases (click here or study). Citation: Pagan ME, Ramseyer AM, Whitcombe DD, Doiron TE, Magann EF, Sandlin AT, Hughes DS. Management of Critically Ill Pregnant Patients with COVID-19 Infection in a Rural State. Am J Perinatol. 2021 Nov 14. doi: 10.1055/s-0041-1739292. Epub ahead of print. PMID: 34775583.

Study 860b – case report from Russia

From S.P. Botkin Infectious Hospital, Saint-Petersburg, which has not previously reported cases (click here or study). Citation: Zinserling VA, Bornstein SR, Narkevich TA, Sukhanova YV, Semenova NY, Vashukova MA, Steenblock C. Stillborn child with diffuse SARS-CoV-2 viral infection of multiple organs. IDCases. 2021;26:e01328. doi: 10.1016/j.idcr.2021.e01328. Epub 2021 Nov 5. PMID: 34777995; PMCID: PMC8570448.

Study 859b – 19 cases from Turkey

From Sakarya University Hospital, (click here or paper). The clinical features differ from those reported in study 474. Citation: Eman A, Balaban O, Kocayiğit H, Süner KÖ, Cırdı Y, Erdem AF. Maternal and Neonatal Outcomes of Critically Ill Pregnant and Puerperal Patients Diagnosed with COVID-19 Disease: Retrospective Comparative Study. J Korean Med Sci. 2021 Nov 15;36(44):e309. doi: 10.3346/jkms.2021.36.e309. PMID: 34783218.

Study 858b – 137 cases from French Guiana

Pregnant women who tested positive and admitted to the maternity of the West French Guiana Hospital Center (Centre Hospitalier de l’Ouest Guyanais, CHOG) from the 16 of June to the 16 of August 2020 (click here or study). This hospital has not previously reported cases. Citation: Hcini, N., Maamri, F., Picone, O., Carod, J.F., Lambert, V., Mathieu, M., et al. (2021) Maternal, Fetal and Neonatal Outcomes of Large Series of SARS-CoV-2 Positive Pregnancies in Peripartum Period: A Single-Center Prospective Comparative Study. European Journal of Obstetrics & Gynecology and Reproductive Biology, 257, 11-18. https://doi.org/10.1016/j.ejogrb.2020.11.068

Update 8 November – study 857 added

Study 857b – 157 cases from Israel

Update of study 714 (click here or study). See also vaccine source 75 (click here). Citation: Romina Plitman Mayo, Tal Raz, Bar Ben David, Gila Meir, Haim Barr, Leonardo J. Solmesky, Rony Chen, Ana Idelson, Lucilla Zorzetti, Rinat Gabbay-Benziv, Yuval Jaffe Moshkovich, Tal Biron-Shental, Gil Shechter-Maor, Hen Yitzhak Sela, Itamar Glick, Hedi Benyamini Raischer, Raed Salim, Yariv Yogev, Ofer Beharier, Debra Goldman-Wohl, Ariel Many, Michal Kovo, Simcha Yagel, Michal Neeman. Waning of the Humoral Response to SARS-CoV-2 in Pregnancy is Variant-Dependent. medRxiv 2021.11.03.21265478; doi: https://doi.org/10.1101/2021.11.03.21265478

Update 7 November – studies 850 to 856 added. Study 732 updated.

Study 856b – 64 cases from Egypt

From an unspecified number “some” of unnamed hospitals (click here or study). From author affliliations they likely include hospitals affiliated with Al-Azhar University, Cairo, Cairo University, Ain Shams University, Cairo, Tanta University, Menoufia University, and Al Zahraa University Hospital, Cairo. Citation: Zaky S, Hosny H, Elassal G, Asem N, Baki AA, Kamal E, Abdelbary A, Said A, Ibrahim H, Taema K, Amin W, Abd-Elsalam S, Soliman S, Abdelmenam HS, Mohamed AS, Elnady M, Hassany M, Zaid H. Clinical evaluation of pregnant women with SARS-COV2 pneumonia: a real-life study from Egypt. J Egypt Public Health Assoc. 2021 Nov 4;96(1):29. doi: 10.1186/s42506-021-00092-z. PMID: 34735655; PMCID: PMC8567119.

Study 855b – 56 cases from Iran

Cared for at Shahid Beheshti Hospital, Kashan, which has not previously reported cases (click here or study). Citation: Abedzadeh-Kalahroudi M, Sehat M, Vahedpour Z, Talebian P. Maternal and neonatal outcomes of pregnant patients with COVID-19: A prospective cohort study. Int J Gynaecol Obstet. 2021 Jun;153(3):449-456. doi: 10.1002/ijgo.13661. Epub 2021 Mar 28. PMID: 33638200.

Study 854b – case report from Iran

From author affiliations likely cared for at Urmia University of Medical Sciences, Urmia (Click here or study). The clinical features differ from study 564. Citation: Nejadrahim R, Khademolhosseini S, Kavandi H, Hajizadeh R. Severe acute respiratory syndrome coronavirus-2- or pregnancy-related cardiomyopathy, a differential to be considered in the current pandemic: a case report. J Med Case Rep. 2021 Mar 19;15(1):143. doi: 10.1186/s13256-021-02751-3. PMID: 33741059; PMCID: PMC7978166.

Study 853b – 106 cases from USA

Cared for by the Maternal Fetal Medicine Division of the University of Texas McGovern Medical School, between
1st May and 31st August 2020. This covers seven hospitals in the Memorial Hermann system in Houston (click here or study). Probable overlap with studies 265b, 643 and 783. Citation: Soto-Torres E, Hernandez-Andrade E, Huntley E, Mendez-Figueroa H, Blackwell SC. Ultrasound and Doppler findings in pregnant women with SARS-CoV-2 infection. Ultrasound Obstet Gynecol. 2021 Jul;58(1):111-120. doi: 10.1002/uog.23642. PMID: 33794060; PMCID: PMC8251118.

Study 852b – 24 cases from Iran

Cared for at Al-Zahra hospital, Tabriz (click here or study). This hospital has not previousy reported cases. Citation: Vaezi M, Mirghafourvand M, Hemmatzadeh S. Characteristics, clinical and laboratory data and outcomes of pregnant women with confirmed SARS-CoV-2 infection admitted to Al-Zahra tertiary referral maternity center in Iran: a case series of 24 patients. BMC Pregnancy Childbirth. 2021 May 17;21(1):378. doi: 10.1186/s12884-021-03764-y. PMID: 34001013; PMCID: PMC8127208.

Study 851b – case report from Spain

From Hospital Clínico Universitario Lozano Blesa, Zaragoza (click here or study). Citation: Abadía-Cuchí N, Ruiz-Martínez S, Fabre M, Mateo P, Remacha Sienes M, Ventura Faci P, Bueno Sancho J, Benito R, Paules C. SARS-CoV-2 congenital infection and pre-eclampsia-like syndrome in dichorionic twins: A case report and review of the literature. Int J Gynaecol Obstet. 2021 Aug;154(2):370-372. doi: 10.1002/ijgo.13749. Epub 2021 Jun 9. PMID: 34009656.

Study 850b – 43 cases from Peru

Cared for at the Instituto Nacional Materno Perinatal (INMP) of Peru, between April 1 and June 30, 2020 (click here or study). Likely overlap with study 114. Citation: Dávila-Aliaga C, Hinojosa-Pérez R, Espinola-Sánchez M, Torres-Marcos E, Guevara-Ríos E, Espinoza-Vivas Y, Mendoza-Ibañez E, Saldaña-Díaz C. Maternal-perinatal outcomes in pregnant women with covid-19 in a level III hospital in Peru. Rev Peru Med Exp Salud Publica. 2021 Jan-Mar;38(1):58-63. Spanish, English. doi: 10.17843/rpmesp.2021.381.6358. Epub 2021 Jun 25. PMID: 34190925.

Update 6 November – studies 846 to 849 added. Study 717 updated.

Study 849b – 1,278 cases from Spain

From the Spanish Obstetric Emergency Group (click here or study). Overlap with studies 246b, 548, 589, 661 and 712. Citation: Sainz Bueno JA, Cerrillos González L, Abascal-Saiz A, Rodríguez Gallego MV, López Pérez R, Fernández Alonso AM, de la Cruz Conty ML, Alonso Saiz R, Molina Oller M, Santamaría Ortiz A, Martínez-Pérez Ó; Spanish Obstetric Emergency Group. Association of ABO and Rh blood groups with obstetric outcomes in SARS-CoV-2 infected pregnancies: A prospective study with a multivariate analysis. Eur J Obstet Gynecol Reprod Biol. 2021 Sep;264:41-48. doi: 10.1016/j.ejogrb.2021.07.008. Epub 2021 Jul 7. PMID: 34271364; PMCID: PMC8260552.

Study 848b – case report from USA

From the University of Texas Health Science Center, Houston (click here or study). May be included in studies 265b or 783. Citation: Mai B, Alrais M, Tchakarov A. A Case Report of Fetal Thrombotic Vasculopathy in a COVID Placenta. Ann Clin Lab Sci. 2021 Jul;51(4):570-572. PMID: 34452898.

Study 847b – case report from Indonesia

From Universitas Airlangga, Surabaya, (click here or study). Possibly included in study 732. Citation: Aldika Akbar MI, Gumilar KE, Tjokroprawiro BA, Ulhaq RA. Successful management of a pregnant woman with COVID-19 and multiple severe complications. BMJ Case Rep. 2021 Sep 16;14(9):e243594. doi: 10.1136/bcr-2021-243594. PMID: 34531234; PMCID: PMC8449948.

Study 846b – 35 cases from Ireland

Twenty three pregnant, and twelve recently pregnant women with Covid admitted to ICU between Dec 2020 & 1 August 2021. There were no such cases prior to that date (click here or study). Overlap with study 858. Citation: National Office of Clinical Audit. NOCA Report on Intensive Care Unit (ICU) Activity during the Covid-19 pandemic. https://www.noca.ie/documents/noca-report-on-icu-activity-during-covid-19-pandemic. Accessed 6 November 2021

Update 30 October – study 863 added

Study 863 – seven pregnant cases from UK

Randomly selected from the routine laboratory reporting system in England from all those who requested a test on 26-27 November 2020 (click here or study). Citation: Frank Sandmann, Elise Tessier, Joanne Lacy, Meaghan Kall, Edwin Van Leeuwen, Andre Charlett, Rosalind M Eggo, Gavin Dabrera, W. John Edmunds, Mary Ramsay, Helen Campbell, Gayatri Amirthalingam, Mark Jit. Long-term health-related quality of life in non-hospitalised COVID-19 cases with confirmed SARS-CoV-2 infection in England: Longitudinal analysis and cross-sectional comparison with controls medRxiv 2021.10.22.21264701; doi: https://doi.org/10.1101/2021.10.22.21264701

Update 29 October – studies 859 to 862 added

Study 862 – 3,306 cases from Italy

From ITOSS (click here or study). Overlap with studies 246, 536, and 674 plus other Italian series. Citation: Donati S, Corsi E, Maraschini A, Salvatore MA; ItOSS- COVID-19 working group. SARS-CoV-2 infection among hospitalized pregnant women and impact of different viral strains on COVID-19 severity in Italy: a national prospective population-based cohort study. BJOG. 2021 Oct 23. doi: 10.1111/1471-0528.16980. Epub ahead of print. PMID: 34687585.

Study 861 – Seven cases from Italy

Identified in a case control study of miscarriage between March 3 and May 25, 2020 at IRCCS Foundation Policlinico San Matteo, Pavia (click here or study). Citation: Zelini P, Dominoni M, Lilleri D, Gardella B, Arossa A, Perotti F, Arrigo A, Spinillo A. Asymptomatic SARS-CoV-2 infection is not associated with miscarriage in early pregnancy: a retrospective analysis. New Microbiol. 2021 Oct 25;44(3). Epub ahead of print. PMID: 34694414.

Study 860 – 197 placentas from USA

From Columbia University – Irving Medical Center, New York (click here or study). The series overlaps with studies 209 and 673, as well as probably also studies 41, 136, 261, 317, 598, 689 and 751. Citation: Thomas J, Sun Y, Debelenko L. Infrequent Placental and Fetal Involvement in SARS-CoV-2 Infection: Pathology Data from a Large Medical Center. J Dev Biol. 2021 Oct 16;9(4):45. doi: 10.3390/jdb9040045. PMID: 34698210; PMCID: PMC8544396.

Study 859 – 2,196 cases from Sweden

Women admitted for delivery between March 11, 2020, and January 31, 2021, as captured from the Swedish Pregnancy Register (click here or study). This appears almost the same cohort as study 688, not cited. It likely also includes cases from studies 20, 88, 259b, 282, 298, 523, 588, 610 & 636. Citation: Stephansson O, Pasternak B, Ahlberg M, Hervius Askling H, Aronsson B, Appelqvist E, Jonsson J, Sengpiel V, Söderling J, Norman M, Ludvigsson JF, Neovius M. SARS-CoV-2 and pregnancy outcomes under universal and non-universal testing in Sweden: register-based nationwide cohort study. BJOG. 2021 Oct 27. doi: 10.1111/1471-0528.16990. Epub ahead of print. PMID: 34706148.

Update 23 October – studies 855 to 858 added

Study 858 – 12 pregnant women in ICU in Ireland in wave 4

Pregnancy was reported in 12 cases of COVID-19 admitted to ICU between 27.06.2021 and 02.10.2021. This is compared to one case in Wave 1 (16.02.2020-01.08.2020), no cases in Wave 2 (02.08.2020-21.11.2020) and 19 cases in Wave 3 (22.11.2020-26.06.2021) (click here or study). Citation: Health Protection Surveillance Centre. Epidemiology of intensive care admissions in cases of COVID-19 in Ireland (among those aged 15 years and older). Report prepared on 05.10.2021 (data from 27.06.2021 to midnight 02.10.2021). https://www.hpsc.ie/a-z/respiratory/coronavirus/novelcoronavirus/surveillance/covid-19intensivecareadmissions/ Accessed 23 October 2021

Study 857 – Case control study from Norway

708 pregnant women aged between 15 and 45 in the Norwegian National Population Registry between March 1st, 2020 and February 28th, 2021, testing positive for SARS-Cov-2, and non pregnant controls (click here or study). Citation: Magnus MC, Oakley L, Gjessing HK, Stephansson O, Engjom HM, Macsali F, Juliusson PB, Andersen AN, Håberg SE. Pregnancy and risk of COVID-19: a Norwegian registry-linkage study. BJOG. 2021 Oct 17. doi: 10.1111/1471-0528.16969. Epub ahead of print. PMID: 34657368.

Study 856 – Placental studies from USA

Placentas from pregnant women cared for at Massachusetts General or Brigham & Women’s Hospital, Boston, Massachussetts, and enrolled in a COVID-19 pregnancy biorepository starting April 2, 2020 (click here or study). Citation: Bordt EA, Shook LL, Atyeo C, Pullen KM, De Guzman RM, Meinsohn MC, Chauvin M, Fischinger S, Yockey LJ, James K, Lima R, Yonker LM, Fasano A, Brigida S, Bebell LM, Roberts DJ, Pépin D, Huh JR, Bilbo SD, Li JZ, Kaimal A, Schust D, Gray KJ, Lauffenburger D, Alter G, Edlow AG. Maternal SARS-CoV-2 infection elicits sexually dimorphic placental immune responses. Sci Transl Med. 2021 Oct 19:eabi7428. doi: 10.1126/scitranslmed.abi7428. Epub ahead of print. PMID: 34664987.

Study 855 – 13,062 cases from Mexico

Data from the Mexican National Registry of Coronavirus April 1st, 2020 to July 31st, 2021 (click here or study). The 3rd overlapping analysis from this source, see studies 513 and 518. Likely also overlap with studies 340, 475, 632, 685, 722, 726, 739, and 768, plus other smaller series from this country. Citation: Torres-Torres, J., Martinez-Portilla, R.J., Espino-y-Sosa, S., Estrada-Gutierrez, G., Solis-Paredes, J.M., Villafan-Bernal, J.R., Medina-Jimenez, V., Rodriguez-Morales, A.J., Rojas-Zepeda, L. and Poon, L.C. (2021), Comorbidities, poverty and social vulnerability as risk factors for mortality in pregnant women with confirmed SARS-CoV-2 infection: analysis of 13 062 positive pregnancies including 176 maternal deaths in Mexico. Ultrasound Obstet Gynecol. Accepted Author Manuscript. https://doi.org/10.1002/uog.24797

Update 18 October – study 854 added

Study 854 – seropositivity in USA

From Hofstra/Northwell in New York between May 2020 and June 2020 (click here or study). Citation: Staszewski C, Rochelson B, Krantz DA, Gerber R, Juhel H, Reddy S, Blitz MJ, Persistence of infection-induced SARS-CoV-2 seropositivity throughout gestation, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.09.037.

Update 13 October – studies 847 to 853 added

Study 853 – 871 cases from India

Cared for at Postgraduate Institute and YCM Hospital Pimpri Pune (Maharashtra) from May 1st, 2020, to April 30th, 2021 (click here or study). Nine mothers died. This hospital has not previously reported cases. Citation: Asalkar M, Thakkarwad S, Rumani I, Sharma N. Prevalence of Maternal Mortality and Clinical Course of Maternal Deaths in COVID-19 Pneumonia-A Cross-Sectional Study. J Obstet Gynaecol India. 2021 Oct 6:1-10. doi: 10.1007/s13224-021-01545-3. Epub ahead of print. PMID: 34629786; PMCID: PMC8492816.

Study 852 – 18 social media self-selected cases

The survey was conducted during May to September 2020 using advertisements on social media from
Canada, USA, UK, India and other countries (click here or study). Citation: Papadopoulos A, Nichols ES, Mohsenzadeh Y, Giroux I, Mottola MF, Van Lieshout RJ, Duerden EG. Depression in pregnant women with and without COVID-19. BJPsych Open. 2021 Sep 21;7(5):e173. doi: 10.1192/bjo.2021.1010. PMID: 34635872; PMCID: PMC8485035.

Study 851 – 101 cases from Poland

Cared for in the Gynecological-Obstetrical Hospital of Poznan University of Medical Sciences, from May to December 2020 (click here or study). This hospital has not previously reported cases. Citation: Wróblewska-Seniuk, K.; Basiukajć, A.; Wojciechowska, D.; Telge, M.; Miechowicz, I.; Mazela, J. Clinical Characteristics of Newborns Born to Mothers with COVID-19. J. Clin. Med. 2021, 10, 4383. https://doi.org/10.3390/jcm10194383

Study 850 – 172 cases from Israel

Cared for at Mayanei Hayeshua Medical Center, in Bnei Brak, between 26 March and 30 September 2020 (click here or study). Likely overlap with study 360. Citation: Linda Harel, Elior Eliasi, Shirlee Jaffe Lifshitz, Yehudit Schindler, Doron Rosen, Ioana Olteanu, Amichai Rottenstreich & Avinoam Tzabari (2021) Does the presence of symptoms affect pregnancy outcomes in third trimester in women with SARS-CoV-2, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2021.1956895

Study 849 – 98 cases from Iran

Collected from hospitals of the Hamadan province from March 2020 until April 2021 (click here or study). The time period and hospital raise the possibility of overlap with studies 375 and 515. Citation: Ghelichkhani S, Jenabi E, Jalili E, Alishirzad A, Shahbazi F. Pregnancy outcomes among SARS-CoV-2-infected pregnant women with and without underlying diseases: a case-control study. J Med Life. 2021 Jul-Aug;14(4):518-522. doi: 10.25122/jml-2021-0157. PMID: 34621376; PMCID: PMC8485375.

Study 848 – 32 seropositive cases from Ecuador

Identified from 100 pregnant women tested in Cgora Women Clinic, Babahoyo from September 3, 2020 to January 31, 2021 (click here or study). The first report from this centre. Citation: Zambrano H, Anchundia K, Aviles D, Andaluz R, Calderon N, Torres E, Gonzalez-Granda N, Maxwell A, Chen K, Gonik B, Mor G. Seroprevalence of SARS-CoV-2 immunoglobulins in pregnant women and neonatal cord blood from a highly impacted region. Placenta. 2021 Oct 6;115:146-150. doi: 10.1016/j.placenta.2021.10.001. Epub ahead of print. PMID: 34626893; PMCID: PMC8492380.

Study 847 – 390 cases from UK

From 1 May, 218 currently pregnant, and 172 recently pregnant women have been admitted to critical care in UK (click here or study). Overlap with previous ICNARC reports Citation: Intensive Care National Audit & Research Centre. ICNARC report on COVID-19 in critical care: England, Wales and Northern Ireland 8 October 2021 Accessed 13 October 2021. https://www.icnarc.org/Our-Audit/Audits/Cmp/Reports

Update 11 October – study 846 added [personal communication Marian Knight]

Study 846 – 1714 cases from UK

This infographic from UKOSS reports that 235/1714 (14%) of UK women admitted with Covid between 1 Feb and 30 September 2021 were also admitted to intensive care (98.7% of them unvaccinated). 13 women (85% known to be unvaccinated) died in the 3rd delta wave (July to September) in UK (click here or source). Although not a peer reviewed report, it comes from an impeccable source, Marian Knight from UKOSS, and the data are important. These numbers includes cases from previous UKOSS reports studies 92, 533, 667 and 764. Citation: Knight M. UKOSS infographic 11 October 2021. Accessed 10 October 2021

Update 26 September – sources 61 to 63 added

4 October 2021 – study 845 added

Study 845 – 66 cases from Canada, UK & France

From the Centre Hospitalier Universitaire Sainte Justine, Montreal, the Childrens Hospital of Eastern Ontario, Ottawa, Centre Hospitalier Universitaire, Nancy, and St-Mary’s Hospital, Manchester (click here or study). Likely included in various national cohorts. Citation: Brien ME, Bouron-Dal Soglio D, Dal Soglio S, Couture C, Boucoiran I, Nasr Y, Widdows K, Sharps MC, El Demellawy D, Ep Heazell A, Menzies D, Girard S. Pandemic stress and SARS-CoV-2 infection are associated with pathological changes at the maternal-fetal interface. Placenta. 2021 Sep 11;115:37-44. doi: 10.1016/j.placenta.2021.09.007. Epub ahead of print. PMID: 34537470; PMCID: PMC8433096.

1 October 2021 – studies 842 to 844 added

Study 844 – 293 cases from USA

Cared for at at the University of Alabama at Birmingham from March 22, 2020, to August 18, 2021 (click here or study). Likely to include cases in studies 480 and 813. Citation: Seasely AR, Blanchard CT, Arora N, Battarbee AN, Casey BM, Dionne-Odom J, Sinkey RG, Szychowski JM, Tita AT, Subramaniam A; CWRH COVID-19 Working Group. Maternal and Perinatal Outcomes Associated With the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Delta (B.1.617.2) Variant. Obstet Gynecol. 2021 Sep 30. doi: 10.1097/AOG.0000000000004607. Epub ahead of print. PMID: 34592747.

Study 843 – 152 cases from USA

Two cohorts of pregnant women testing positive for SARS-CoV-2 infection between March to July 2020, and July to August 2021 and cared for at the University of Texas Medical Branch at Galveston, Texas (click here or study). The earlier cohort of 91 cases were reported in study 616. Citation: Wang AM, Berry M, Moutos CP, Omere C, Clark SM, Harirah HM, Jain S, Olson GL, Pacheco LD, Saade GR, Saad AF. Association of the Delta (B.1.617.2) Variant of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) With Pregnancy Outcomes. Obstet Gynecol. 2021 Sep 30. doi: 10.1097/AOG.0000000000004595. Epub ahead of print. PMID: 34592748.

Study 842 – 100 pregnant women treated with ECMO

Collected by the Extracorporeal Life Support Organization (ELSO) registry from 349 centres in 41 countries (click here or study). Includes cases from study 535. Citation: Barbaro R, MacLaren G, Boonstra PS et al. Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the International Extracorporeal Life Support Organization Registry. Lancet. 2021; (published online Sept 29.) https://doi.org/10.1016/S0140-6736(21)01960-7

30 September 2021 – study 840 added

Study 841 – 167 cases from Turkey

Cared for at Bursa City Hospital, Bursa, which has not previously reported cases, between April 1, and December 1, 2020 (click here or study). Citation: Aydın GA, Ünal S, Özsoy HGT. The effect of gestational age at the time of diagnosis on adverse pregnancy outcomes in women with COVID-19. J Obstet Gynaecol Res. 2021 Sep 28. doi: 10.1111/jog.15051. Epub ahead of print. PMID: 34585464.

Study 840 – 1,645 cases from India

Cared for at Nair hospital, Mumbai from 1st April 2020 to 12th July 2021 (click here or study). Likely overlap with studies 225, 283, 369, 501, 520, 547, 746, 777, 778 and 839. Citation: N.N. Mahajan, C. Gaikwad, R. Tayshete, C. Saldanha, R. Pednekar, S.D. Mahale, R.K.Gajbhiye, Increased stillbirth rate during the second wave of COVID-19 pandemic in India, European Journal of Obstetrics & Gynecology and Reproductive Biology (2021), doi: https://doi.org/10.1016/j.ejogrb.2021.09.030

29 September 2021 – study 839 added

Study 839 – 1,630 cases from India

Cared for at Nair hospital, Mumbai from 1st April 2020 to 4th July 2021 (click here or study). Likely overlap with studies 225, 283, 369, 501, 520, 547, 746, 777 and 778. Citation: Gajbhiye, R.K., Tilve, A., Kesarwani, S., Srivastava, S., Kore, S.J., Patil, K., Mahale, S.D. and Mahajan, N.N. (2021), Increased spontaneous abortions during the second wave of COVID-19 pandemic in India. Ultrasound Obstet Gynecol. Accepted Author Manuscript. https://doi.org/10.1002/uog.24784

28 September 2021 – country and hospital of study 838 updated. HT @joallotey

27 September 2021 – studies 836 and 838 added

Study 838 – case report from India

The patient gave birth at Mal Superspeciality Hospital, West Bengal, which has not previously reported cases, on 11th June 2021 (click here or study). Citation: Kalsar P, Datta S, Kalsar A, Kipkoech Kirui B, Kanyike AM. Severe Postpartum Hemorrhage in an Asymptomatic COVID-19 Patient: A Call to Be on Guard. Int Med Case Rep J. 2021;14:683-687 https://doi.org/10.2147/IMCRJ.S334249

Study 837 – 51 cases from Iraq

From Al Yarmouk Teaching Hospital, in Baghdad (click here or study). One woman, excluded from the main study, died. Citation: Nori W, Hameed BH, Thamir AR, Fadhil A. COVID-19 in Pregnancy: Implication on Platelets and Blood Indices. Rev Bras Ginecol Obstet. 2021 Aug;43(8):595-599. English. doi: 10.1055/s-0041-1733912. Epub 2021 Sep 21. PMID: 34547793.

Study 836 – 72 cases from Japan

A survey of 1,418 maternity institutions identified 72 pregnant women with COVID-19 between 16 January and 30 June 2020 (click here or study). One woman, a tourist, needed ventilation and later died. Citation: Arakaki, T., Hasegawa, J., Sekizawa, A. et al. Clinical characteristics of pregnant women with COVID-19 in Japan: a nationwide questionnaire survey. BMC Pregnancy Childbirth 21, 636 (2021). https://doi.org/10.1186/s12884-021-04113-9

26 September 2021 – studies 828 to 835 added

Study 835 – two cases from USA

Cared for by Zucker School of Medicine at Hofstra/Northwell and Northwell Health between June 26th and September 4th 2020 (click here or study). None of 96 women undergoing Caesrean section, who were negative on admision, got infected. Citation: Nizam A, Nimaroff ML, Menzin AW, Goldberg GL, Miyara SJ, Molmenti E. Nosocomial Covid-19 Infection in Women Undergoing Elective Cesarean Sections: A prospective cohort study. Am J Obstet Gynecol MFM. 2021 Sep 17:100490. doi: 10.1016/j.ajogmf.2021.100490. Epub ahead of print. PMID: 34543753; PMCID: PMC8447544.

Study 834 – 45 cases from UK

Cared for in five unnamed NHS hospitals within London, and three outside, between 16 November 2020 and 10 January 2021 (click here or study). Citation: Stirrup O, Boshier F, Venturini C, Guerra-Assunção JA, Alcolea-Medina A, Beckett A, Charalampous T, da Silva Filipe A, Glaysher S, Khan T, Kulasegaran Shylini R, Kele B, Monahan I, Mollett G, Parker M, Pelosi E, Randell P, Roy S, Taylor J, Weller S, Wilson-Davies E, Wade P, Williams R; COG-UK-HOCI Variant substudy consortium; COVID-19 Genomics UK (COG-UK) consortium, Copas A, Cutino-Moguel MT, Freemantle N, Hayward AC, Holmes A, Hughes J, Mahungu T, Nebbia G, Partridge D, Pope C, Price J, Robson S, Saeed K, de Silva T, Snell L, Thomson E, Witney AA, Breuer J. SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study. BMJ Open Respir Res. 2021 Sep;8(1):e001029. doi: 10.1136/bmjresp-2021-001029. PMID: 34544733; PMCID: PMC8453594.

Study 833 – 1,515 cases from the USA

Cared for at the Parkland Health & Hospital System, Dallas, from May 17, 2020 through September 4, 2021 (click here or study). Likely overlap with studies 186 and 361. Citation: Adhikari EH, SoRelle JA, McIntire DD, Spong CY. Increasing severity of COVID-19 in pregnancy with Delta (B.1.617.2) variant surge. Am J Obstet Gynecol. 2021 Sep 13:S0002-9378(21)01005-X. doi: 10.1016/j.ajog.2021.09.008. Epub ahead of print. PMID: 34529957; PMCID: PMC8437765.

Study 832 – 15 cases from Ireland

Cared for at the Rotunda Hospital, Dublin and delivered between January and March 2021 (click here or study). This hospital has previously reported cases (studies 300, 596 & 676) but the dates suggest no overlap. Nor do the dates overlap with the Republic of Ireland’s Covid-19 register report, study 284. Citation: C.A. Murphy, D.P. O’reilly, O. Edebiri, L. Weiss, S. Cullivan, A. EL-Khuffash, E. Doyle, J.C. Donnelly, F.D. Malone, W. Ferguson, R.J. Drew, J. O’loughlin, E. Neary, P.B. Maguire, B. Kevane, F. Níainle, n. Mccallion, Haematological parameters and coagulation in umbilical cord blood following COVID-19 infection in pregnancy, European Journal of Obstetrics & Gynecology and Reproductive Biology (2021), doi: https://doi.org/10.1016/j.ejogrb.2021.09.019

Study 831 – 381 cases from India

Cared for at the Government Rajaji Hospital (GRH) & Medical College, Madurai, neither of which have previously reported cases, between March 22 and August 31, 2020 (click here or study). Citation: Priyadharshini CB, Priya S, Selvameena M, Waseemsha S, Muthurajesh E, Shalini M. Demographic profile of COVID-19 positive mothers & their outcome in government Rajaji hospital, Madurai, Tamilnadu – A cross sectional Study. Clin Epidemiol Glob Health. 2021 Oct-Dec;12:100864. doi: 10.1016/j.cegh.2021.100864. Epub 2021 Sep 10. PMID: 34541381; PMCID: PMC8432978.

Study 830 – 19 cases from Nigeria

Cared for at the University of Benin Teaching Hospital, Benin City, which has not previously reported cases, from April to September 2020 (click here or study). Citation: James Osaikhuwuomwan et al. Clinical characteristics and outcomes for pregnant women diagnosed with COVID-19 disease at the University of Benin Teaching Hospital, Benin City, Nigeria. Pan African Medical Journal. 2021;39(134). 10.11604/pamj.2021.39.134.27627

Study 829 – ICNARC update

This consortium collects cases from critical care in England, Wales and Northern Ireland (click here or study). See fig 28, p 40 (and others) for pregnancy. Citation: Intensive Care National Audit & Research Centre. ICNARC report on COVID-19 in critical care: England, Wales and Northern Ireland 17 September 2021 Accessed 26 September 2021. https://www.icnarc.org/Our-Audit/Audits/Cmp/Reports

Study 828 – 8,555 cases from ISARIC

This MedRxiv preprint reports that after adjusting for age, and stratifying by country, pregnancy was associated with a lower risk of death (HR 0.44 [0.38, 0.50] for females aged 15 to 45 (click here or study). The pregnancy cases are in supplementary table 5 (click here). The ISARIC consortium covers 720 sites across 49 countries. Citation: ISARIC Clinical Characterisation Group, Christiana Kartsonaki. Characteristics and outcomes of an international cohort of 400,000 hospitalised patients with Covid-19. medRxiv 2021.09.11.21263419; doi: https://doi.org/10.1101/2021.09.11.21263419 [Important, control group]

11 September 2021 – study 827 added

Study 827 – 36 cases from the Netherlands

Cared for at Erasmus Medical Center, Ikazia hospital, and Franciscus Gasthuis & Vlietland hospitals, all in Rotterdam, and at Leiden University Medical Center in Leiden, between April 2020 and March 2021 (click here or study). Citation: Husen, M.F.; van der Meeren, L.E.; Verdijk, R.M.; Fraaij, P.L.A.; van der Eijk, A.A.; Koopmans, M.P.G.; Freeman, L.; Bogers, H.; Trietsch, M.D.; Reiss, I.K.M.; DeKoninck, P.L.J.; Schoenmakers, S. Unique Severe COVID-19 Placental Signature Independent of Severity of Clinical Maternal Symptoms. Viruses 2021, 13, 1670. https://doi.org/10.3390/v13081670

9 September 2021 – study 826 added. Study 141 updated.

Study 826 – 376 cases from the Netherlands

From the NethOSS registry between March 1st, and August 31st, 2020 (click here or study). Likely overlap with studies 262, 373 and 528 as well as study 545 and other reports from the NethOSS registry. No maternal deaths, although one had been reported in the 22 May update of the NethOSS website (study 141). See study 141, 9 September update. Citation: Overtoom, E.M., Rosman, A.N., Zwart, J.J., Vogelvang, T.E., Schaap, T.P., van den Akker, T. and Bloemenkamp, K.W. (2021), SARS-CoV-2 infection in pregnancy during the first wave of COVID-19 in the Netherlands: a prospective nationwide population-based cohort study (NethOSS). BJOG: An International Journal of Obstetrics & Gynaecology. Accepted Author Manuscript. https://doi.org/10.1111/1471-0528.16903 [Important, control group]

8 September 2021 – studies 814 to 825 added. Study 716 updated.

Study 825 – 5,614 cases from Colombia

Collected by Colombia’s Instituto Nacional de Salud, Sivigila surveillace system from 6 March to 12 December 2020 (click here or study). Likely overlap with study 420. Citation: Rozo N, Valencia D, Newton SM, Avila G, Gonzalez MA, Sancken CL, Burkel VK, Ellington SR, Gilboa SM, Rao CY, Azziz-Baumgartner E, Ospina ML, Prieto FE, Tong VT. Severity of illness by pregnancy status among laboratory-confirmed SARS-CoV-2 infections occurring in reproductive-aged women in Colombia. Paediatr Perinat Epidemiol. 2021 Sep 1. doi: 10.1111/ppe.12808. Epub ahead of print. PMID: 34467554.

Study 824 – 233 cases from USA

Cared for at NYU Langone Health-Tisch, NYU Langone Health-Brooklyn, or Bellevue Hospital Center, New York from 1 March to 1 July 2020 (click here or study). Likely overlap with many studies. Citation: Limaye MA, Roman AS, Trostle ME, Venkatesh P, Lantigua Martinez M, Brubaker SG, Chervenak J, Wei LS, Sahani P, Grossman TB, Meyer JA, Penfield CA. Predictors of severe and critical disease in pregnant women with SARS-CoV-2. J Matern Fetal Neonatal Med. 2021 Sep 1:1-5. doi: 10.1080/14767058.2021.1951216. Epub ahead of print. PMID: 34470122.

Study 823 – 39 cases with rheumatic disease

Collected by the COVID-19 Global Rheumatology Alliance (click here or study). Citation: Bermas BL, Gianfrancesco M, Tanner HL, Seet AM, Aguiar MC, Al Adhoubi NK, Emadi SA, Cunha BM, Flood R, Kusevich DA, McCarthy EM, Patel NJ, Ruderman E, Sattui SE, Sciascia S, Siddique F, Valenzuela-Almada MO, Wise LM, Worthing AB, Zell J, Bhana S, Costello W, Duarte-Garcia A, Grainger R, Gossec L, Hausmann JS, Hyrich K, Lawson-Tovey S, Liew JW, Sirotich E, Sparks J, Sufka P, Wallace Z, Machado PM, Strangfeld A, Clowse MEB, Yazdany J, Robinson PC. COVID-19 in women with rheumatic disease who are pregnant: Data from the COVID-19 Global Rheumatology Alliance. J Rheumatol. 2021 Sep 1:jrheum.210480. doi: 10.3899/jrheum.210480. Epub ahead of print. PMID: 34470798.

Study 822 – 312 cases from Iran

Cared for at Nekouei-Hedayati-Forghani Hospital in Qom, from 15 March to 15 November 2020 (click here or study). Details of only 133 cases are reported. Likely overlap with studies 555 and 567. Citation: Alipour Z, Samadi P, Eskandari N, Ghaedrahmati M, Vahedian M, Khalajinia Z, Mastanijahroodi A. Relationship between coronavirus disease 2019 in pregnancy and maternal and fetal outcomes: Retrospective analytical cohort study. Midwifery. 2021 Aug 25;102:103128. doi: 10.1016/j.midw.2021.103128. Epub ahead of print. PMID: 34474247; PMCID: PMC8384487. PubPeer comment click here

Study 821 – 494 cases from USA

Survey conducted by Kaiser Permanente Northern California of women who were pregnant between January 1, 2020 and April 28, 2021 (click here or study). Likely overlap with study 414. Citation: Ames JL, Ferrara A, Avalos LA, Badon SE, Greenberg MB, Hedderson MM, Kuzniewicz MW, Qian Y, Young-Wolff KC, Zerbo O, Zhu Y, Croen LA. COVID-19 prevalence, symptoms, and sociodemographic disparities in infection among insured pregnant women in Northern California. PLoS One. 2021 Sep 3;16(9):e0256891. doi: 10.1371/journal.pone.0256891. PMID: 34478463; PMCID: PMC8415576.

Study 820 – 163 cases from USA

Collected by Cuyahoga County Board of Health, Cleveland, Ohio, with illness onset dates from March 13 through August 21, 2020 (click here or study). Possible overlap with study 198. Citation: Miracle JE, Ganesh PR, Rose J, Terebuh P, Stange KC, Wolfe HM, Szabo A, Gullett H, Pope R. COVID-19 in Pregnancy: Occupations with Higher Density of Population Exposure Associated with More Severe Disease. J Occup Environ Med. 2021 Sep 2. doi: 10.1097/JOM.0000000000002374. Epub ahead of print. PMID: 34483305.

Study 819 – 989 cases from india

956 were pregnant and 33 postpartum, collected from 53 hospitals participating in the Federation of Obstetric and Gynaecological Societies of India (FOGSI) COVID registry from 28 April to 28 August 2020 (click here or study). The hospitals are not named. Citation: Gandhi AM, Ganatra AM, Tank P. Preliminary Results from the FOGSI’s National Registry on Pregnancy with COVID-19. J Obstet Gynaecol India. 2021 Aug 31:1-8. doi: 10.1007/s13224-021-01537-3. Epub ahead of print. PMID: 34483513; PMCID: PMC8405343.

Study 818 – case report from Brazil

From author affiliations cared for at Maternity School, Federal University of Rio de Janeiro, which has not previously reported cases (click here or study). Citation: Marinho PS, da Cunha AJLA, Chimelli L, Avvad-Portari E, Andreiuolo FDM, de Oliveira-Szejnfeld PS, Mendes MA, Gomes IC, Souza LRQ, Guimarães MZ, Goldman SM, de Oliveira MBG, Rehen S, Amim J Jr, Tovar-Moll F, Prata-Barbosa A. Case Report: SARS-CoV-2 Mother-to-Child Transmission and Fetal Death Associated With Severe Placental Thromboembolism. Front Med (Lausanne). 2021 Aug 16;8:677001. doi: 10.3389/fmed.2021.677001. PMID: 34485327; PMCID: PMC8415358.

Study 817 – 24 cases from Bosnia & Herzegovina

From the Cantonal Hospital Zenica which has not previously reported cases (click here or study). Citation: Hodžić J, Muračević B, Štimjanin H, Iriškić R, Husika M. Pregnancy outcomes of COVID-19 positive pregnant women at the Cantonal Hospital Zenica, Bosnia and Herzegovina. Med Glas (Zenica). 2022 Feb 1;19(1). doi: 10.17392/1407-21. Epub ahead of print. PMID: 34486362.

Study 816 – 127 cases from India

From author affiliations likely cared for at Kalinga Institute of Medical Sciences, Bhubaneswar, which has not previously reported cases (click here or study). Citation: Mohini Ahmed S, Kasarla. V, Rath SK, Worse Outcomes of Pregnancy in COVID-19 Infection during Parturition may be due to Referral Bias: Analysis in a Prospective Cohort of 963 pregnancies, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/
j.ajog.2021.08.058.

Study 815 – two cases from the Czech Republic

Country assumed from journal title. Full text and journal source not found (click here or study). Citation: Čivrná J, Skanderová D, Ehrmann J, Pilka R. HELLP syndrome and HELLP-like syndrome in pregnancies with covid-19 – case reports. Ceska Gynekol. 2021 Summer;86(4):236-241. English. doi: 10.48095/cccg2021236. PMID: 34493047.

Study 814 – 22 cases from Brazil

From author affiliations the unnamed hospital is likely in Campinas, Sao Paolo (click here or study). Citation: Freitas-Jesus JV, Sánchez ODR, Rodrigues L, Faria-Schützer DB, Serapilha AAA, Surita FG. Stigma, guilt and motherhood: Experiences of pregnant women with COVID-19 in Brazil. Women Birth. 2021 Aug 27:S1871-5192(21)00151-7. doi: 10.1016/j.wombi.2021.08.009. Epub ahead of print. PMID: 34493479.

2 September 2021 – Studies 809 to 813 added

Study 813 – 99 cases from USA

Of 1,413 pregnant women, less than 28 weeks gestation, prospectively enrolled during August 2020–February 2021, who self-swabbed weekly, 99 tested positive (click here or study). They were cared for at three U.S. medical centers in Salt Lake City, Utah, New York City, and Birmingham, Alabama. It is not possible to identify the treating centres from author affliations. Citation: Fatimah S Dawood, Michael Varner, Alan Tita, Gabriella Newes-Adeyi, Cynthia Gyamfi-Bannerman, Ashley Battarbee, Ann Bruno, Michael Daugherty, Lawrence Reichle, Kelly Vorwaller, Celibell Vargas, Mickey Parks, Emily Powers, Miriam Lucca-Susana, Marie Gibson, Akila Subramaniam, Yiling J Cheng, Pei-Jean Feng, Sascha Ellington, Romeo R Galang, Jennifer Meece, Chris Flygare, Melissa S Stockwell, Incidence, Clinical Characteristics, and Risk Factors of SARS-CoV-2 Infection among Pregnant Individuals in the United States, Clinical Infectious Diseases, 2021;, ciab713, https://doi.org/10.1093/cid/ciab713

Study 812 – case report from Brazil

From Hospital Universitário Oswaldo Cruz, Recife, Pernambuco, which has not previously reported cases (click here or study). However she might be included in study 761. Citation: Gama MDP, Angelo Júnior JRL, Cunha-Correia CD. Stroke in COVID-19 and Pregnancy: A Case Report. Rev Soc Bras Med Trop. 2021 Aug 20;54:e03012021. doi: 10.1590/0037-8682-0301-2021. PMID: 34431948.

Study 811 – 267 cases from USA

Clinical nasopharyngeal or lateral mid-turbinate nasal swabs obtained during inpatient and outpatient encounters across the five acute hospitals in Johns Hopkins Medical System, as well as several long-term care facilities in the State of Maryland (click here or study). Citation: Chun Huai Luo, C. Paul Morris, Jaiprasath Sachithanandham, Adannaya Amadi, David Gaston, Maggie Li, Nicholas J. Swanson, Matthew Schwartz, Eili Y. Klein, Andrew Pekosz, Heba H. Mostafa. Infection with the SARS-CoV-2 Delta Variant is Associated with Higher Infectious Virus Loads Compared to the Alpha Variant in both Unvaccinated and Vaccinated Individuals. medRxiv 2021.08.15.21262077; doi: https://doi.org/10.1101/2021.08.15.21262077

Study 810 – 2,604 cases from USA

Taken from electronic medical record data from 182 Hospital Corporation of America (HCA) hospitals across the US between March 1, and August 23, 2020 (click here or study). 2,604 out of 84,624 patients with Covid were pregnant. Six died. Likely overlap with many previous US series. Citation: Adam V. Delora, Ashlynn Mills, David Jacobson, Brendon Cornett, W. Frank Peacock, Anita Datta, Shane Jenks. Socioeconomic and comorbid factors affecting mortality and length of stay in COVID-19. medRxiv 2021.08.26.21262693; doi: https://doi.org/10.1101/2021.08.26.21262693

Study 809 – two cases from Sri Lanka

Two pregnant health care workers tested positive for SARS CoV-2 in this series from Base Hospital, Wathupitiwala, which has not previously reported cases (click here or study). Citation: W.A.M.P. Samaranayake, G.P.C. Jayawardena, A.L.L. Roshan, M.A.M. Wijewardene, M.I. Siraj. COVID-19 infection among health care workers: Experience in Base Hospital Wathupitiwala, Sri Lanka. medRxiv 2021.08.28.21262733; doi: https://doi.org/10.1101/2021.08.28.21262733

31 August 2021 – studies 803 to 808 (Recovery trials with pregnant participants) added, some belatedly

Study 808 – 25 pregnant women in UK Recovery casirivimab & imdevimab trial

Their group allocation was not reported in this MedRxiv preprint of this trial of Regeneron’s monoclonal antibody combination, casirivimab and imdevimab, “REGEN-COV” (click here or study). Citation: RECOVERY Collaborative Group, Peter W Horby, Marion Mafham, Leon Peto, Mark Campbell, Guilherme Pessoa-Amorim, Enti Spata, Natalie Staplin, Jonathan R Emberson, Benjamin Prudon, Paul Hine, Thomas Brown, Christopher A Green, Rahuldeb Sarkar, Purav Desai, Bryan Yates, Tom Bewick, Simon Tiberi, Tim Felton, J Kenneth Baillie, Maya H Buch, Lucy C Chappell, Jeremy N Day, Saul N Faust, Thomas Jaki, Katie Jeffery, Edmund Juszczak, Wei Shen Lim, Alan Montgomery, Andrew Mumford, Kathryn Rowan, Guy Thwaites, David M Weinreich, Richard Haynes, Martin J Landray. Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. medRxiv 2021.06.15.21258542; doi: https://doi.org/10.1101/2021.06.15.21258542

Study 807 – 10 pregnant women in UK Recovery tocilizumab trial

Group allocation not reported (click here or study). Citation: RECOVERY Collaborative Group. Tocilizumab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. Lancet. 2021 May 1;397(10285):1637-1645. doi: 10.1016/S0140-6736(21)00676-0. PMID: 33933206; PMCID: PMC8084355.

Study 806 – 58 pregnant women in UK Recovery aspirin trial

Their group allocation was not reported in this MedRxiv preprint (click here or study). Citation: RECOVERY Collaborative Group, Peter W Horby, Guilherme Pessoa-Amorim, Natalie Staplin, Jonathan R Emberson, Mark Campbell, Enti Spata, Leon Peto, Nigel J Brunskill, Simon Tiberi, Victor Chew, Thomas Brown, Hasan Tahir, Beate Ebert, David Chadwick, Tony Whitehouse, Rahuldeb Sarkar, Clive Graham, J Kenneth Baillie, Buddha Basnyat, Maya H Buch, Lucy C Chappell, Jeremy Day, Saul N Faust, Raph L Hamers, Thomas Jaki, Edmund Juszczak, Katie Jeffery, Wei Shen Lim, Alan Montgomery, Andrew Mumford, Kathryn Rowan, Guy Thwaites, Marion Mafham, Richard Haynes, Martin J Landray. Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. medRxiv 2021.06.08.21258132; doi: https://doi.org/10.1101/2021.06.08.21258132

Study 805 – 25 pregnant women in UK Recovery azithromycin trial

Group allocation not reported (click here or study). Citation: RECOVERY Collaborative Group. Azithromycin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. Lancet. 2021 Feb 13;397(10274):605-612. doi: 10.1016/S0140-6736(21)00149-5. Epub 2021 Feb 2. PMID: 33545096; PMCID: PMC7884931.

Study 804 – Six pregnant women in UK Recovery Lopinavir–ritonavir trial

Group allocation not reported (click here or study). Citation: RECOVERY Collaborative Group. Lopinavir-ritonavir in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial. Lancet. 2020 Oct 24;396(10259):1345-1352. doi: 10.1016/S0140-6736(20)32013-4. Epub 2020 Oct 5. PMID: 33031764; PMCID: PMC7535623.

Study 803 – Four pregnant women in UK Recovery dexamethasone trial

One in treatment group and three in usual care (click here or study). Citation: RECOVERY Collaborative Group, Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, Linsell L, Staplin N, Brightling C, Ustianowski A, Elmahi E, Prudon B, Green C, Felton T, Chadwick D, Rege K, Fegan C, Chappell LC, Faust SN, Jaki T, Jeffery K, Montgomery A, Rowan K, Juszczak E, Baillie JK, Haynes R, Landray MJ. Dexamethasone in Hospitalized Patients with Covid-19. N Engl J Med. 2021 Feb 25;384(8):693-704. doi: 10.1056/NEJMoa2021436. Epub 2020 Jul 17. PMID: 32678530; PMCID: PMC7383595.

28 August 2021 – studies 801 and 802 added

Study 802 – case report from Italy

The hospital and date of delivery are not stated, but from ethics approval the former was in Brescia (click here or study). The case is likely included in the various Lombardy series. Citation: Schwartz DA, Bugatti M, Santoro A, Facchetti F. Molecular Pathology Demonstration of SARS-CoV-2 in Cytotrophoblast from Placental Tissue with Chronic Histiocytic Intervillositis, Trophoblast Necrosis and COVID-19. J Dev Biol. 2021 Aug 25;9(3):33. doi: 10.3390/jdb9030033. PMID: 34449643.

Study 801 – case report from Austria

From author affiliations cared for at the Medical University of Vienna, which has not previously reported cases, in October 2020 (click here or study). Citation: Palmrich P, Roessler B, Wisgrill L, Kampf S, Gattinger P, Valenta R, Fleischmann E, Berger A, Kiss H, Farr A. Multiprofessional perinatal care in a pregnant patient with acute respiratory distress syndrome due to COVID-19. BMC Pregnancy Childbirth. 2021 Aug 26;21(1):587. doi: 10.1186/s12884-021-04059-y. PMID: 34445988.

22 August 2021 – studies 797 to 800 added

Study 800 – 234 cases from Spain

Cared for in the 14 Neo-COVID-19 Research Group hospitals so likely included in many previous series (click here or study). Citation: Neo-COVID-19 Research Group:, Marín Gabriel MA, Domingo Goneche L, Cuadrado Pérez I, Reyne Vergeli M, Forti Buratti A, Royuela Vicente A, Olabarrieta Arnal I, Sánchez L, Alonso Díaz C, Criado E, Carrizosa Molina T, Caserío Carbonero S, Casas Satre C, Fernández-Cañadas Morillo A; Authoring Group (Neo-COVID-19 Research Group). Baby Friendly Hospital Initiative Breastfeeding Outcomes in Mothers with COVID-19 Infection During the First Weeks of the Pandemic in Spain. J Hum Lact. 2021 Aug 10:8903344211039182. doi: 10.1177/08903344211039182. Epub ahead of print. PMID: 34374323.

Study 799 – 512 cases from India

Cared for at Employees State Insurance Corporation Medical College and Hospital, Faridabad, Haryana, between April–December 2020 (click here or study). This hospital has not previously reported cases. Citation: Gupta P, Khatana VP, Prabha R, Jha I, Singh M, Pandey AK, Kesri A. An observational study for appraisal of clinical outcome and risk of mother-to-child SARS-CoV-2 transmission in neonates provided the benefits of mothers’ own milk. Eur J Pediatr. 2021 Aug 11:1–15. doi: 10.1007/s00431-021-04206-9. Epub ahead of print. PMID: 34379196; PMCID: PMC8355567.

Study 798 – 50 cases from Russia

From Samara Regional Clinical Hospital named after V.D. Seredavin, which has not previously reported cases (click here or study [full text not available]). Citation: Borodina IA, Gil’miyarova FN, Gusyakova OA, Selezneva IA, Borisova OV, Potyakina EE, Kolot’eva NA, Kozlov AV, Gorbacheva IV, Kuznecova OY, Baldina OA, Vinogradova LN, Emel’yanova NG, Koroteeva YA. Newborns from women infected with COVID-19: somatic and metabolic status. Klin Lab Diagn. 2021 Aug 13;66(8):453-458. English. doi: 10.51620/0869-2084-2021-66-8-453-458. PMID: 34388314.

Study 797 – two cases from South Korea

Both cared for at the National Health Insurance Service Ilsan Hospital which has not previously reported cases (click here or study). Citation: Jin JH, Kim Y, Yoo J, Kim EH, Yoon SW. Two Cases of SARS-CoV-2-Positive Mothers and Their Newborns in Korea. Infect Chemother. 2021 Jul 28. doi: 10.3947/ic.2021.0027. Epub ahead of print. PMID: 34405595.

21 August 2021 – studies 795 and 796 added

Study 796 – 224 cases from Turkey

Pregnant women with covid over 32 weeks, cared for between August and October 2020 at Ankara City Hospital (click here or study). Likely overlap with studies 203, 223, 399, 512, 569, 604 and 640. Citation: Sinaci S, Ocal DF, Ozden Tokalioglu E, Halici Ozturk F, Aydin Senel S, Keskin LH, Moraloglu Tekin O, Sahin D. Cardiotocographic features in COVID-19 infected pregnant women. J Perinat Med. 2021 Aug 19. doi: 10.1515/jpm-2021-0132. Epub ahead of print. PMID: 34411469.

Study 795 – 8,957 cases from USA

These were live births between July 2020 and January 2021 documented by California Vital Statistics birth certificates, using data received by the California Preterm Birth Initiative by March 1, 2021, with a COVID-19 diagnosis in pregnancy (click here or study). Likely overlap with studies 222, 226, 228, 323, 388, 414, 600, 680, 696, and 697. Citation: D. Karasek, R.J. Baer, M.R. McLemore et al., The association of COVID-19 infection in pregnancy with preterm birth: A retrospective cohort study in California, The Lancet Regional Health – Americas, https://doi.org/10.1016/j.lana.2021.100027

19 August 2021 – studies 792 to 794 added

Study 794 – 7,432 cases from USA

Data from Epic’s Cosmos research platform which covers one third of the hospitals in the United States (click here or paper). There was no difference in adverse pregnancy outcomes between 7,432 patients with a SARS-CoV-2 positive test and 100,635 SARS-CoV-2 negative controls. See also paper 91 here. Citation: Moeun Son, Kieran Gallagher, Justin Y. Lo, Eric Lindgren, Heather H. Burris, Kevin Dysart, Jay Greenspan, Jennifer F. Culhane, and Sara C. Handley. Coronavirus Disease 2019 (COVID-19) Pandemic and Pregnancy Outcomes in a U.S. Population Obstet Gynecol 2021;00:1–10) DOI: 10.1097/AOG.0000000000004547

Study 793 – 175 cases from USA

Cared for at Northwestern Memorial Hospital, in Chicago, Illinois, between March and October 2020 (click here or study). Likely overlap with studies 116, 124 and 251, although none of these studies were cited. Citation: Stephanie A. FISHER, Jeffery A. GOLDSTEIN, Leena B. MITHAL, Alexandra L. ISAIA, Elisheva D. SHANES, Sebastian OTERO, Emily S. MILLER. Laboratory Analysis of Symptomatic and Asymptomatic Pregnant Patients with SARS-CoV-2 Infection, American Journal of Obstetrics & Gynecology MFM (2021), doi: https://doi.org/10.1016/j.ajogmf.2021.100458

Study 792 – Case report from Iran

Cared for in April 2020 at Shariati Hospital, Tehran University of Medical Sciences, North-Kargar Avenue, Tehran (click here or study). The only previous report from this hospital, study 287, describes two patients with different clinical features. The first author Amir Hossein Norooznezhad has the same name as the last author on study 43 which was retracted due to the case having been included in an earlier series (study 67). However study 67‘s last author was affiliated with a different university, namely, Kermanshah University of Medical Sciences, Kermanshah. Citation: Norooznezhad, A.H., Nurzadeh, M., Darabi, M.H. et al. Coronavirus disease 2019 (COVID-19) in a pregnant women with treatment resistance thrombocytopenic purpura with and suspicion to HELLP syndrome: a case report. BMC Pregnancy Childbirth 21, 567 (2021). https://doi.org/10.1186/s12884-021-04030-x

18 August 2021 – study 791 added

Study 791 – 1,582 cases from India

Among 1,582 pregnant and post-partum women with COVID-19, admitted to six COVID-19 hospitals participating in the PregCovid registry from April 2020 to January 2021, 31 had sickle cell disease or were carriers (click here or study). The unnamed hospitals were in Nagpur, Chandrapur, Akola, Yavatmal, and Mumbai but cannot be precisely identified from author affiliations. Likely overlap with studies 283 and 514. Citation: Waghmare, R., Chaaithanya, I.K., Zala, S. et al. Outcomes of COVID-19 in Pregnant Women with Sickle Cell Disease in India: A Case Series. Indian J Hematol Blood Transfus (2021). https://doi.org/10.1007/s12288-021-01482-1

15 August 2021 – studies 789 and 790 added

Study 790 – 10 cases from Argentina

Cared for in four hospitals in the San Isidro district of Buenos Aires, from March 1, to October 31 2020 (click here or study). The hospitals were San Isidro, Las Lomas, San Lucas, and Trinidad, none of which have previously reported cases. Citation: Maria Ana Barra, Nelson Adolfo Carlos Medinacelli, Camilo Andres Meza Padilla, Lucrecia Di Rocco, Ramiro Manuel Larrea, Giuliano Gaudenzi, Veronica Vanesa Mastrovincenzo, Ines Moreno, Elisa Rana, Dagmar Ana Sorvik, Andrea Sarlingo, Florencia Dadomo, Miguel Torrilla. COVID-19 in hospitalized patients in 4 hospitals in San Isidro, Buenos Aires, Argentina. medRxiv 2021.07.30.21261220; doi: https://doi.org/10.1101/2021.07.30.21261220

Study 789 – 218 cases from USA

Cared for at four medical centers in New Jersey between 10 April and 15 June 2020 (click here or study). The centres were the Robert Wood Johnson University Hospital, New Brunswick (overlap with studies 86, 285 & 392), Saint Barnabas Medical Center, Livingston (86 & 111), Monmouth Medical Center, Long Branch (no previous reports), and Clara Maass Medical Center, Belleville (no previous reports). Citation: Hill J, Patrick HS, Ananth CV, O’Brien D, Spernal S, Horgan R, Brandt JS, Schwebel M, Miller RC, Straker MJ, Graebe RA, Rosen T. Obstetrical outcomes and follow-up for patients with asymptomatic COVID-19 at delivery: A multicenter prospective cohort study. Am J Obstet Gynecol MFM. 2021 Aug 7:100454. doi: 10.1016/j.ajogmf.2021.100454. Epub ahead of print. PMID: 34375750; PMCID: PMC8349406.

14 August 2021 – studies 781 to 788 added

Study 788 – seven cases from Italy

From Fondazione IRCCS Policlinico San Matteo, Pavia (click here or study). Listed also as Source 60 here. Citation: Cassaniti I, Percivalle E, Zelini P, Nanhorngue KN, Parolo A, Bernardi V, Jorizzo G, Santer P, Perotti F, Spinillo A, Lilleri D, Baldanti F. Both SARS-CoV-2 infection and vaccination in pregnancy elicited neutralizing antibodies in pregnant women and newborns. Clin Microbiol Infect. 2021 Aug 6:S1198-743X(21)00442-0. doi: 10.1016/j.cmi.2021.08.004. Epub ahead of print. PMID: 34371204; PMCID: PMC8349424.

Study 787 – 18,715 cases from USA

Data collected by the Vizient Clinical Data Base/Resource Manager, an administrative, clinical, and financial database of more than 650 academic centers and their community affiliates, which claims to cover 97% of US academic medical centers (click here or study). 24 women died. Presumably overlap with other US series and especially those of the CDC and SET-NET consortium. Citation: Chinn J, Sedighim S, Kirby KA, Hohmann S, Hameed AB, Jolley J, Nguyen NT. Characteristics and Outcomes of Women With COVID-19 Giving Birth at US Academic Centers During the COVID-19 Pandemic. JAMA Netw Open. 2021 Aug 2;4(8):e2120456. doi: 10.1001/jamanetworkopen.2021.20456. PMID: 34379123; PMCID: PMC8358731.

Study 786 – 46 cases from Spain

Cared for at La Paz University, 12 de Octubre, Quironsalud Madrid, and Quironsalud San José hospitals, all in Madrid between April and July 2020 (click here or study). Likelylincluded in many previous Madrid series. Citation: Sánchez García L, Gómez-Torres N, Cabañas F, González-Sánchez R, López-Azorín M, Moral-Pumarega MT, Escuder-Vieco D, Cabañes-Alonso E, Castro I, Alba C, Rodríguez Gómez JM, Pellicer A. Immediate Pre-Partum SARS-CoV-2 Status and Immune Profiling of Breastmilk: A Case-Control Study. Front Immunol. 2021 Jul 26;12:720716. doi: 10.3389/fimmu.2021.720716. PMID: 34381462; PMCID: PMC8350512.

Study 785 – 16 cases from Morocco

From the Moroccan Military Hospital in Benslimane, from July 21 to October 21, 2020 (click here [english] or study [in French]). This hospital has not previously reported cases. Citation: Benlghazi A, Benali S, Bouhtouri Y, Belouad M, Massoudi H, Kouach J. Infection SARS-CoV-2 chez la femme enceinte; profil épidémiologique, clinique, biologique et évolutifs, à propos de 16 cas: expérience de l’Hôpital Militaire Marocain COVID-19 de Benslimane [SARS-CoV-2 infection in pregnant women; epidemiological, clinical, biological and evolutionary profile in 16 cases: the COVID-19 experience in the Moroccan Military Hospital in Benslimane]. Pan Afr Med J. 2021 Apr 20;38:384. French. doi: 10.11604/pamj.2021.38.384.28695. PMID: 34381528; PMCID: PMC8325444.

Study 784 – 4 cases from UK

From Chelsea & Westminster and West Middlesex Hospitals, London (click here or study). Likely included in many other UK series. Citation: Thorne I, Steele S, Martineau M, Girling J. Case series of COVID-19 infection in pregnancy complicated by ketoacidosis and symptomatic breathlessness. Obstetric Medicine. July 2021. doi:10.1177/1753495X211024511

Study 783 – 61 cases from USA

Patients admitted to one of four unnamed hospitals affiliated with the University of Texas Health Science Center at Houston between May 4, and July 26, 2020 (click here or study). Possible overlap with studies 265b, 576 and 643. Citation: Pineles BL, Stephens A, Narendran LM, Tigner A, Leidlein C, Pedroza C, Mendez-Figueroa H, Sibai BM. The Relationship Between Delivery and the PaO2/FiO2 ratio in COVID-19: A Cohort Study. BJOG. 2021 Aug 10. doi: 10.1111/1471-0528.16858. Epub ahead of print. PMID: 34375031.

Study 782 – case report from India

From Holy Family Hospital Bandra, Mumbai, which has not previously reported cases (click here or study). Citation: Kripalani Y, Parulekar L. Pulmonary Embolism in a COVID-19-Positive Primigravida After Caesarean Section Despite Prophylaxis. Eur J Case Rep Intern Med. 2021 Jul 16;8(7):002684. doi: 10.12890/2021_002684. PMID: 34377695; PMCID: PMC8336743.

Study 781 – case report from India

From All India Institute of Medical Sciences (AIIMS), Patna, which has not previously reported cases (click here or study). Citation: Agarwal M, Singh S, Sinha U, Bhushan D. Extrahepatic portal vein thrombosis in a pregnant patient with COVID-19: a rare thrombotic event survivor. BMJ Case Rep. 2021 Aug 12;14(8):e243697. doi: 10.1136/bcr-2021-243697. PMID: 34385221.

9 August 2021 – studies 779 and 780 added

Study 780 – some cases from India

Seven cases are described, but the abstract mentions 109, and the tables are ambiguous. Patients were cared for at Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha (click here or study). This hospital has not previously reported cases. Citation: Panda A, Das S, Satapathy GC. Perioperative Obstetric Care in Coronavirus Infectious Disease 2019: Anesthetic Perspective. Anesth Essays Res. 2020 Oct-Dec;14(4):584-588. doi: 10.4103/aer.AER_4_21. Epub 2021 May 27. PMID: 34349324; PMCID: PMC8294413. Comment. Although listed on PubMed, and not by Beall, this journal has some predatory features; submission as well as processing charges, and no institutional contact emails. It is published by the “Pan Arab Federation of Societies of Anesthesiologists”, which elsewhere on the internet is called the “Pan Arab Federation of Societies of Anaesthesia, Intensive Care and Pain Management”. Administrative functions are conducted by, and fees directed to, Wolters Kluwer India Pvt. Ltd. (Medknow), A-202, 2nd Floor The Qube, C.T.S. No.1498A/2, Village Marol, Andheri (East), Mumbai, Maharashtra 400059.

Study 779 – two cases from United Arab Emirates

Treated at Sheikh Khalifa Medical City, Abu Dhabi, in May and June 2020 (click here or study). This hospital has not previously reported cases. Citation: Abdullah S, Bashir N, Mahmood N. Use of intravenous tocilizumab in pregnancy for severe coronavirus disease 2019 pneumonia: two case reports. J Med Case Rep. 2021 Aug 7;15(1):426. doi: 10.1186/s13256-021-03010-1. PMID: 34364393.

8 August 2021 – studies 772 to 778 added

Study 778 – 18 cases from India

Six with concurrent pulmonary tuberculosis, and 12 with previously cured TB, and Covid in pregnancy (click here or study). Selected from 879 pregnant or postpartum women with COVID-19 cared for at Nair Hospital, Mumbai from April to September 2020. Citation: Gajbhiye RK, Mahajan NN, Kamath N, Bahirat S, Patokar G, Bhurke AV, Modi DN, Mahale SD. Clinical presentations, pregnancy complications, and maternal outcomes in pregnant women with COVID-19 and tuberculosis: A retrospective cohort study. Int J Gynaecol Obstet. 2021 Apr;153(1):176-179. doi: 10.1002/ijgo.13588. Epub 2021 Feb 11. PMID: 33421126; PMCID: PMC7611277.

Study 777 – case report from India

A woman contracted Covid in pregnancy at 12 weeks, miscarried at 13 and developed Guillain-Barré syndrome (click here or study). From Nair hospital, Mumbai, so likely included in previous series. Citation: Mahajan NN, Srivastava S, Chakor R, More P, Mahale SD, Gajbhiye RK. Neurological complications of COVID-19 and spontaneous abortion in a pregnant woman – A case report. Eur J Obstet Gynecol Reprod Biol. 2021 Aug;263:278-279. doi: 10.1016/j.ejogrb.2021.06.010. Epub 2021 Jun 16. PMID: 34175157; PMCID: PMC8206547.

Study 776 – 115 cases from India

All delivered by elective cesarean under spinal from July 2020 to December 2020 at Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Srinagar, Jammu and Kashmir, which has not previously reported cases (click here or study). Citation: Jan M, Bhat WM, Rashid M, Ahad B. Elective Cesarean Section in Obstetric COVID-19 Patients under Spinal Anesthesia: A Prospective Study. Anesth Essays Res. 2020 Oct-Dec;14(4):611-614. doi: 10.4103/aer.AER_29_21. Epub 2021 May 27. PMID: 34349329; PMCID: PMC8294416.

Study 775 – Case control study from Italy

From Sant Anna Hospital, Turin, for delivery between 20 September 2020 and 9 January 2021 (click here or study). Likely overlap with studies 79, 167, 195, 247, 615, and possibly 644. Citation: Cosma S, Carosso AR, Cusato J, Borella F, Carosso M, Gervasoni F, Stura I, Preti M, Ghisetti V, Di Perri G, Benedetto C. Preterm birth is not associated with asymptomatic/mild SARS-CoV-2 infection per se: Pre-pregnancy state is what matters. PLoS One. 2021 Aug 5;16(8):e0254875. doi: 10.1371/journal.pone.0254875. PMID: 34351922; PMCID: PMC8341509.

Study 774 – 393 cases from Europe

Collected by the PregOuTCOV group from 4 university hospitals in Europe (click here or study. Also appendix). From author affiliations University Hospital Brugmann, Brussels, Belgium, Louis Mourier Hospital, Colombes, France, Gemelli University Polyclinic Foundation, Rome, Italy and Antoine Béclère Hospital, Clamart, France, which have all previously reported cases. Citation: Badr DA, Picone O, Bevilacqua E, Carlin A, Meli F, Sibiude J, Mattern J, Fils JF, Mandelbrot L, Lanzone A, De Luca D, Jani JC, Vivanti AJ. Severe Acute Respiratory Syndrome Coronavirus 2 and Pregnancy Outcomes According to Gestational Age at Time of Infection. Emerg Infect Dis. 2021 Aug 5;27(10). doi: 10.3201/eid2710.211394. Epub ahead of print. PMID: 34352196.

Study 773 – 9 cases from Germany

One baby, exposed at weeks 5 and 6, had unilateral microphthalmia, optic nerve hypoplasia, and congenital retinopathy (click here or study). From University of Erlangen-Nürnberg, Erlangen, which has not previously reported cases. Citation: Morhart P, Mardin C, Rauh M, Jüngert J, Hammersen J, Kehl S, Schuh W, Maier-Wohlfart S, Hermes K, Neubert A, Schneider M, Hein A, Woelfle J, Schneider H. Maternal SARS-CoV-2 infection during pregnancy: possible impact on the infant. Eur J Pediatr. 2021 Aug 5:1–6. doi: 10.1007/s00431-021-04221-w. Epub ahead of print. PMID: 34355278; PMCID: PMC8341836.

Study 772 – 18 cases from India

Twenty babies with features of neonatal multisystem inflammatory syndrome in children (MIS-C) were born to eighteen mothers with a history of COVID-19 disease or exposure during pregnancy (click here or study). The babies were cared for in seven NICUs in Kolhapur, Maharashtra, a city from which previous maternal cases have not been reported. Citation: Pawar R, Gavade V, Patil N, Mali V, Girwalkar A, Tarkasband V, Loya S, Chavan A, Nanivadekar N, Shinde R, Patil U, Lakshminrusimha S. Neonatal Multisystem Inflammatory Syndrome (MIS-N) Associated with Prenatal Maternal SARS-CoV-2: A Case Series. Children (Basel). 2021 Jul 2;8(7):572. doi: 10.3390/children8070572. PMID: 34356552.

2 August 2021 – studies 765 to 771 added

Study 771 – 97 cases from USA

Cared for at Weill Cornell Medicine, New York (click here or study). Likely overlap with studies 99, 118, 216, 230, 234, 276, 578, 669, and 758. Citation: Glynn SM, Yang YJ, Thomas C, Friedlander RL, Cagino KA, Matthews KC, Riley LE, Baergen RN, Prabhu M. SARS-CoV-2 and Placental Pathology: Malperfusion Patterns Are Dependent on Timing of Infection During Pregnancy. Am J Surg Pathol. 2021 Jul 26. doi: 10.1097/PAS.0000000000001772. Epub ahead of print. PMID: 34310367.

Study 770 – 40 cases from Turkey

Cared from Basaksehir Cam and Sakura City Hospital, Istanbul, which has not previously reported cases (click here or study). Citation: Yasa B, Memur S, Ozturk DY, Bagci O, Uslu SI, Polat I, Cetinkaya M. Severity of Maternal SARS-CoV-2 Infection in Pregnancy Predicts Neonatal Outcomes. Am J Perinatol. 2021 Jul 28. doi: 10.1055/s-0041-1733783. Epub ahead of print. PMID: 34320680.

Study 769 – 85 cases from USA

Cared for at any of fourteen Advocate Aurora Health medical centers in Wisconsin and Illinois between March 23 and October 3, 2020 (click here or study). Three women required ventilation, but no mothers or babies died. This hospital network has not previously reported cases. Citation: Zlochiver V, Tilkens B, Perez Moreno AC, Aziz F, Jan MF. COVID-19 Deliveries: Maternal Features and Neonatal Outcomes. J Patient Cent Res Rev. 2021 Jul 19;8(3):286-289. doi: 10.17294/2330-0698.1848. PMID: 34322584; PMCID: PMC8297489.

Study 768 – 53 cases from Mexico

Cared for at the UMAE Hospital de Gineco Obstetricia “Luis Castelazo Ayala” Instituto Mexicano del Seguro Social, Mexico City from January to April 2021 (click here or study). This hospital has not previously reported cases, although they are likely included in the various national Mexico series. Citation: Carranza Lira S, Espinosa MG. Differences in the neutrophil/lymphocyte ratio and the platelet/lymphocyte ratio in pregnant women with and without COVID-19. Int J Gynaecol Obstet. 2021 Jul 29. doi: 10.1002/ijgo.13840. Epub ahead of print. PMID: 34322880.

Study 767 – 20 cases from China

From Tongji Hospital, Wuhan, between March 18 and May 9 2020 (click here or study). Likely reported many times before. Citation: Chen G, Zhang Y, Zhang Y, Ai J, Yang B, Cui M, Liao Q, Chen H, Bai H, Shang D, Chen J, Sun C, Liu H, Liu F, Mao B, Sun G, Chen L, Lin JW, Li K. Differential immune responses in pregnant patients recovered from COVID-19. Signal Transduct Target Ther. 2021 Jul 29;6(1):289. doi: 10.1038/s41392-021-00703-3. PMID: 34326311; PMCID: PMC8320317.

Study 766 – 14 cases from Italy

Asymptomatic or mild, but otherwise no clinical details (click here or study). Citation: De Biasi S, Tartaro DL, Gibellini L, Paolini A, Quong A, Petes C, Awong G, Douglas S, Lin D, Nieto J, Galassi FM, Borella R, Fidanza L, Mattioli M, Leone C, Neri I, Meschiari M, Cicchetti L, Iannone A, Trenti T, Sarti M, Girardis M, Guaraldi G, Mussini C, Facchinetti F, Cossarizza A. Endogenous control of inflammation characterizes pregnant women with asymptomatic or paucisymptomatic SARS-CoV-2 infection. Nat Commun. 2021 Jul 29;12(1):4677. doi: 10.1038/s41467-021-24940-w. PMID: 34326336.

Study 765 – 5 cases from France

From author affiliations the patients were cared for at a l’Hopital Femme-M`ere-Enfant, Hospices Civils de Lyon, which has not previously reported cases (click here or study). Hower they may be included in study 150. Citation: Bouachba A, Allias F, Nadaud B, Massardier J, Mekki Y, Bouscambert Duchamp M, Fourniere B, Huissoud C, Trecourt A, Collardeau-Frachon S. Placental lesions and SARS-Cov-2 infection: Diffuse placenta damage associated to poor fetal outcome. Placenta. 2021 Jul 15;112:97-104. doi: 10.1016/j.placenta.2021.07.288. Epub ahead of print. PMID: 34329973; PMCID: PMC8280612.

26 July 2021 – study 764 added

Study 764 – 3,371 cases from UK

This MedRxiv preprint reports that compared with the first wave (wildtype SARS-CoV-2 predominant), pregnant women admitted to hospital during the 2nd wave (alpha variant predominant) had an increased risk of moderate or severe disease, aOR 1.75 (95% CI 1.48-2.06) (click here or study). Pregnant women admitted during the 3rd wave (delta predominant), had a further increase in risk, aOR 1.53 (1.07-2.17). No fully vaccinated pregnant women were admitted between 01/02/2021 when vaccination data collection commenced and 11/07/2021. This series includes cases from previous UKOSS reports studies 92, 533 and 667 as well as other UK series. Citation: Nicola Vousden, Rema Ramakrishnan, Kathryn Bunch, Edward Morris, Nigel Simpson, Christopher Gale, Patrick O’Brien, Maria Quigley, Peter Brocklehurst, Jennifer J Kurinczuk, Marian Knight. Impact of SARS-CoV-2 variant on the severity of maternal infection and perinatal outcomes: Data from the UK Obstetric Surveillance System national cohort. medRxiv 2021.07.22.21261000; doi: https://doi.org/10.1101/2021.07.22.21261000 [important]

24 July 2021 – studies 759 to 763 added

Study 763 – case report from Iran

From Shahid Beheshti University of Medical Sciences, Tehran (click here or study). Citation: Naseh A, Ashrafzadeh S. Possible Vertical Transmission From an Unsuspected SARS-CoV-2-Infected Mother to Her Newborn. Cureus. 2021 Jun 17;13(6):e15717. doi: 10.7759/cureus.15717. PMID: 34290917; PMCID: PMC8288625.

Study 762 – 56 cases from Italy

Cared for at “L. Sacco” University Hospital, Milan between March 7th and April 30th, 2020 (click here or study). The cases appear to overlap with study 312 and other series from Milan. Citation: Fenizia C, Saulle I, Di Giminiani M, Vanetti C, Trabattoni D, Parisi F, Biasin M, Savasi V. Unlikely SARS-CoV-2 Transmission During Vaginal Delivery. Reprod Sci. 2021 Jul 22. doi: 10.1007/s43032-021-00681-5. Epub ahead of print. PMID: 34296422.

Study 761 – 338 cases from Brazil

Collected by 16 maternity hospitals from the Brazilian network of COVID-19 during pregnancy (REde BRAsileira em estudos do COVID-19 em Obstetrícia REBRACO) up to July 2020 (click here or study). 29 mothers died. of whom 15 deaths were attributed to COVID-19. From author affiliations the hospitals were: Sao Paolo; University of Campinas, Faculdade de Medicina de Jundiaı´, Universidade Federal de São Carlos, Universidade Federal de São Paulo, Hospital Regional Jorge Rossmann Instituto So´crates Guanaes, Itanhae´m, Hospital Estadual Sumare´, Faculdade de Medicina da Universidade Estadual de São Paulo; plus Hospital das Clı´nicas de Porto Alegre, Maternidade UNIMED, Belo Horizonte, Universidade Federal do Ceara´, Fortaleza, Hospital Moinhos de Vento, Porto Alegre, Universidade Federal de Minas Gerais, Belo Horizonte, Instituto Fernandes Figueira, Rio de Janeiro, Universidade Federal de Pernambuco, Recife, Maternidade Clime´rio de Oliveira, Salvador, and Santa Casa de Miserico´rdia do Para´, Bele´m’. Likely overlap with other studies from Brazil. Citation: Costa ML, Souza RT, Pacagnella RC, Bento SF, Ribeiro-do-Valle CC, Luz AG, et al. (2021) Facing the COVID-19 pandemic inside maternities in Brazil: A mixed-method study within the REBRACO initiative. PLoS ONE 16(7): e0254977. https://doi.org/10.1371/journal.pone.0254977

Study 760 – 22 infected placentas from 7 countries

They were reviewed by a panel of pathologists (click here or study). Citation: Schwartz DA, Baldewijns M, Benachi A, Bugatti M, Bulfamante G, Cheng K, Collins RRJ, Debelenko L, De Luca D, Facchetti F, Fitzgerald B, Levitan D, Linn RL, Marcelis L, Morotti D, Morotti R, Patanè L, Prevot S, Pulinx B, Saad AG, Schoenmakers S, Strybol D, Thomas K, Tosi D, Toto V, van der Meeren LE, Verdijk RM, Vivanti AJ, Zaigham M. Hofbauer cells and coronavirus disease 2019 (COVID-19) in pregnancy: Molecular pathology analysis of villous macrophages, endothelial cells, and placental findings from 22 placentas infected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) with and without fetal transmission. Arch Pathol Lab Med. 2021 Jul 23. doi: 10.5858/arpa.2021-0296-SA. Epub ahead of print. PMID: 34297794.

Study 759 – Case report from USA

From Vassar Brothers Medical Center, Poughkeepsie, New York state (click here or study), so may be included in study 371. Citation: Abdulraheem, E, Shaikhoun, M, Kung, D. Severe peripartum cardiomyopathy complicated by COVID-19 infection and small intestinal obstruction. Clin Case Rep. 2021; 9:e04505. https://doi.org/10.1002/ccr3.4505

22 July 2021 – study 758 added

Study 758 – 88 cases from USA

Maternal and cord serology (click here or study). From author affiliations delivered at Weill Cornell Medicine, New York between April 18 and May 31, 2020. Likely overlap with studies 99, 118, 216, 230, 234, 276, 578 and 669. Citation: Kubiak JM, Murphy EA, Yee J, et al. Severe acute respiratory syndrome coronavirus 2 serology levels in pregnant women and their neonates. Am J Obstet Gynecol 2021;225:73.e1-7

21 July 2021 – studies 756 and 757 added

Study 757 – case report from the Slovak Republic

From author affiliations cared for at Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, which has not previously reported cases (click here or study). Citation: Kamil Biringer, Jana Sivakova, Juraj Marcinek, Terezia Pribulova, Tomas Rokos, Erik Kozubik, Erik Kudela, Lukas Plank. Placental pathology concerning sudden foetal demise in SARS-CoV-2 positive asymptomatic pregnant female. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2021; 165:XX

Study 756 – 926 cases from COVI-preg

Collected by the approximately 81 centres, from 15 countries, participating in the COVI-Preg registry between March 24 and July 26, 2020 (click here or study). Click here for centres. Likely overlap with other series. Citation: Vouga, M., Favre, G., Martinez-Perez, O. et al. Maternal outcomes and risk factors for COVID-19 severity among pregnant women. Sci Rep 11, 13898 (2021). https://doi.org/10.1038/s41598-021-92357-y

20 July 2021 – study 755 added

Study 755 – case report from Spain

The patient had SARS-CoV-2 infection in the first trimester (click here or study). From author affiliations she was probably cared for at Hospital Clínico San Carlos de Madrid, so possibly also included in study 196. Citation: Fuentes Carrasco M, Mayoral Triana A, Cristóbal García IC, Pérez Pérez N, Izquierdo Méndez N, Soler Ruiz P, González González V. Catastrophic antiphospholipid syndrome during pregnancy. Eur J Obstet Gynecol Reprod Biol. 2021 Jul 7;264:21-24. doi: 10.1016/j.ejogrb.2021.07.002. Epub ahead of print. PMID: 34273751; PMCID: PMC8260489.

19 July 2021 – Study 754 added

Study 754 – 8,564 cases from ISARIC

This MedRxiv ISARIC (International Severe Acute Respiratory and emerging Infections Consortium) preprint of cases up to 25 May 2021, includes 8,564 pregnant women (click here or study). Collected by 1,651 sites across 63 countries. Citation: ISARIC Clinical Data Report issued: 14 July 2021. ISARIC Clinical Characterisation Group, Kenneth Baillie, … Laura Merson et al. medRxiv 2020.07.17.20155218; doi: https://doi.org/10.1101/2020.07.17.20155218

18 July 2021 – studies 751 to 753 added

Study 753, – 75 cases from Turkey

From Sanliurfa Training and Research Hospital between April and August 2020 (click here or study). This hospital has not previously reported cases. Citation: Damar Çakırca T, Torun A, Hamidanoğlu M, Portakal RD, Ölçen M, Çakırca G, Haksever M. COVID-19 infection in pregnancy: a single center experience with 75 cases. Ginekol Pol. 2021 Jul 15. doi: 10.5603/GP.a2021.0118. Epub ahead of print. PMID: 34263921.

Study 752 – 45 cases from Switzerland

This MedRxiv preprint reports participants of the Swiss COGEN Cohort study diagnosed between February and December 2020 at University Hospital Basel, University Hospital Zurich, University Hospital Bern, and the Cantonal Hospital Baden (click here or study). Being pregnant at the time of acute COVID-19 illness (OR 0.48 [0.23-1.01], p=0.054) was associated with lower odds of post COVID syndrome. Probable overlap with cases reported in studies 72, 310, 427 and 526. Citation: Caroline E. Gebhard, Claudia Sütsch, Susan Bengs, Manja Deforth, Karl Philipp Buehler, Nadia Hamouda, Alexander Meisel, Reto A. Schuepbach, Annelies S. Zinkernagel, Silvio D. Brugger, Claudio Acevedo, Dimitri Patriki, Benedikt Wiggli, Jürg H. Beer, Andrée Friedl, Raphael Twerenbold, Gabriela M. Kuster, Hans Pargger, Sarah Tschudin-Sutter, Joerg C. Schefold, Thibaud Spinetti, Arnaud Dussault-Cloutier, Chiara Henze, Mina Pasqualini, Dominik F. Sager, Lilian Mayrhofer, Mirjam Grieder, Janna Tontsch, Fabian Franzeck, Pedro D. Wendel Garcia, Daniel A. Hofmaenner, Thomas Scheier, Jan Bartussek, Leon Chrobok, David Stähli, Nicola Lott, Ahmed Haider, Muriel Grämer, Nidaa Mikail, Alexia Rossi, Nuria Zellweger, Petra Opic, Angela Portmann, Atanas Todorov, Aju P. Pazhenkottil, Michael Messerli, Ronny R. Buechel, Philipp A. Kaufmann, Valerie Treyer, Martin Siegemund, Ulrike Held, Vera Regitz-Zagrosek, Catherine Gebhard. Sex- and Gender-specific Risk Factors of Post-COVID-19 Syndrome: A Population-based Cohort Study in Switzerland. medRxiv 2021.06.30.21259757; doi: https://doi.org/10.1101/2021.06.30.21259757 [Long covid]

Study 751 – 107 cases from USA

From Columbia University Irving Medical Center – affiliated, New York Presbyterian (NYP), Morgan Stanley Children’s Hospital, and NYP Allen Pavilion Hospitals, New York, from 3/13/2020 (click here or study). Likely overlap with other studies from these hospitals. See also indirect effects, Paper 77 (click here). Citation: Lauren C. Shuffrey, Morgan R. Firestein, Margaret Kyle, Andrea Fields, Carmela Alcantara, Dima Amso, Judy Austin, Jennifer M. Bain, Jennifer Barbosa, Mary Bence, Catherine Bianco, Cristina Fernandez, Sylvie Goldman, Cynthia Gyamfi-Bannerman, Violet Hott, Yunzhe Hu, Maha Hussain, Pam Factor-Litvak, Maristella Lucchini, Arthur Mandel, Rachel Marsh, Danielle McBrian, Mirella Mourad, Rebecca Muhle, Kimberly Noble, Anna A. Penn, Cynthia Rodriguez, Ayesha Sania, Wendy G. Silver, Kally C. O Reilly, Melissa Stockwell, Nim Tottenham, Martha G. Welch, Noelia Zork, William P. Fifer, Catherine Monk, Dani Dumitriu. Birth during the COVID-19 pandemic, but not maternal SARS-CoV-2 infection during pregnancy, is associated with lower neurodevelopmental scores at 6-months medRxiv 2021.07.12.21260365; doi: https://doi.org/10.1101/2021.07.12.21260365

12 July 2021 – studies 747 to 750 added

Study 750 – 58 cases from India

Cared for between June and September 2020 at Bharati Vidyapeeth hospital, in Pune, which has not previously reported cases (click here or study). One mother died. Citation: Malshe N, Patnaik SK, Lalwani S, Suryawanshi P, Kulkarni R, Mhaske S, Mishra AC, Arankalle V. Perinatal transmission of SARS-CoV-2 and transfer of maternal IgG/neutralizing anti-SARS-CoV-2 antibodies from mothers with asymptomatic infection during pregnancy. Infection. 2021 Jul 7:1–7. doi: 10.1007/s15010-021-01650-5. Epub ahead of print. PMID: 34232457; PMCID: PMC8262126.

Study 749 – 42 cases from Iran

From the hospitals of Shahid Beheshti University of Medical Sciences, Tehran between 21 February and 30 November 2020, so likely overlap with study 514 (click here or study). Two mothers died. Citation: Hosseini MS, Hosseini A, Ghaffari E, Radfar M, Shirvani F, Tabatabai S, Abtahi D, Mirhadi M, Mortazavi M, Ariana S. Evaluation of clinical outcomes of neonates born to mothers with coronavirus (COVID-19) in Shahid Beheshti Hospitals. J Educ Health Promot. 2021 May 31;10(1):173. doi: 10.4103/jehp.jehp_20_21. PMID: 34250107; PMCID: PMC8249960.

Study 748 – 65 cases from India

From Sarojini Naidu Medical College, Agra, Uttar Pradesh, which has not previously reported cases, between April 15 and June 30, 2020 (click here or study). Citation: Agarwal N, Garg R, Singh S, Agrawal A. Coronavirus disease 2019 in pregnancy: Maternal and perinatal outcome. J Educ Health Promot. 2021 May 31;10(1):194. doi: 10.4103/jehp.jehp_954_20. PMID: 34250128; PMCID: PMC8249977.

Study 747 – 70 women with past SARS-CoV-2 infection undergoing assisted conception in China

Fourteen conceived, which was similar to the rate among those without past infection (click here or study). From Tongji Hospital, Wuhan between May 2020 and February 2021. Citation: Wang M, Yang Q, Ren X, Hu J, Li Z, Long R, Xi Q, Zhu L, Jin L. Investigating the impact of asymptomatic or mild SARS-CoV-2 infection on female fertility and in vitro fertilization outcomes: A retrospective cohort study. EClinicalMedicine. 2021 Aug;38:101013. doi: 10.1016/j.eclinm.2021.101013. Epub 2021 Jul 6. PMID: 34250457; PMCID: PMC8259363.

10 July 2021 – study 697 citation updated.

9 July 2021 – study 746 added

Study 746 – 1,530 cases from India

From Nair hospital in Mumbai between 1 April 2020 and 14 May 2021, so overlap with previous cases from that hospital (click here or study. Appendix here). 30 mothers died, with maternal mortality, ICU admission and severity significantly higher during the 2nd wave. Citation: Mahajan, Niraj N. MD; Pophalkar, Madhura MS; Patil, Sarika MPhil; Yewale, Bhagyashree MBBS; Chaaithanya, Itta Krishna PhD; Mahale, Smita D. PhD; Gajbhiye, Rahul K. MBBS, PhD Pregnancy Outcomes and Maternal Complications During the Second Wave of Coronavirus Disease 2019 (COVID-19) in India, Obstetrics & Gynecology: July 7, 2021 – Volume – Issue – 10.1097/AOG.0000000000004529
doi: 10.1097/AOG.0000000000004529

8 July 2021 – studies 743 to 745 added

Study 745 – 217 cases from Turkey

Cared for in an unnamed tertiary medical centre between 1 March and 30 November 2020 (click here or study). Citation: Bozkurt F, Çoşkun Ö, Yeleç S, Bekçibaşi M, Asena M, Bağli I. Comparison of the Clinical and Laboratory Findings in COVID-19 Positive Pregnants without Comorbidity. Turk J Med Sci. 2021 Jul 8. doi: 10.3906/sag-2105-116. Epub ahead of print. PMID: 34233388.

Study 744 – 17 maternal deaths in UK

The second MBRRACE report (July 2021) includes ten pregnant or recently pregnant women who died from Covid-19, four who died from other causes with SARS-CoV-2 infection, and three whose deaths were indirectly caused by the pandemic (click here or study). This report covers 01/06/2020 to 31/03/2021, and therefore excludes cases in the previous MBRRACE report (study 255). Citation: Knight M, Bunch K, Cairns A, Cantwell R, Cox P, Kenyon S, Kotnis R, Lucas DN, Lucas S, Nelson-Piercy C, Patel R, Rodger A, Shakespeare J, Tuffnell D, Kurinczuk JJ on behalf of MBRRACE-UK. Saving Lives, Improving Mothers’ Care Rapid Report 2021: Learning from SARS-CoV-2-related and associated maternal deaths in the UK June 2020-March 2021. Oxford: National Perinatal Epidemiology Unit, University of Oxford 2021. ISBN: 978-1-8383678-2-4

Study 743 – 426 cases admitted to ICU in UK

The 5 July 2021 ICNARC report (click here or study). Pregnancy p74. Thirteen pregnant or recently pregnant woman have died. Citation: Intensive Care National Audit & Research Centre. ICNARC report on COVID-19 in critical care: England, Wales and Northern Ireland 5 July 2021 Accessed 8 July 2021. https://www.icnarc.org/Our-Audit/Audits/Cmp/Reports

7 July 2021 – Studies 738 and 742 added

Study 742 – 11,247 cases from Brazil

1,031 of the mothers died (click here or study). Collected by the Obstetric Observatory, so overlap with study 724, and many other series from Brazil. Citation: Francisco RPV, Lacerda L, Rodrigues AS. Obstetric Observatory BRAZIL – COVID-19: 1031 maternal deaths because of COVID-19 and the unequal access to health care services. Clinics (Sao Paulo). 2021 Jun 28;76:e3120. doi: 10.6061/clinics/2021/e3120. PMID: 34190858; PMCID: PMC8221555.

Study 741 – 16 possible cases from Kenya

(click here or study [no pdf available]). Citation: Otieno NA, Azziz-Baumgartner E, Nyawanda BO, Oreri E, Ellington S, Onyango C, et al. SARS-CoV-2 infection among pregnant and postpartum women, Kenya, 2020–2021. Emerg Infect Dis. 2021 Sep [date cited]. https://doi.org/10.3201/eid2709.210849

Study 740 – 1,295 cases from Spain

Recruited by the Spanish Obstetrics Emergency Group between 1 March and 3 November 2020, so included in many previous studies (click here or study). Citation: Cuñarro-López Y, Pintado-Recarte P, Hernández-Martín C, Paya-Martínez P, López-Pérez R, Cueto-Hernández I, Ruiz-Labarta J, Cano-Valderrama Ó, Martínez-Pérez Ó, Bravo-Arribas C, Ortega MA, De León-Luis JA. Comparing Infection Profiles of Expectant Mothers with COVID-19 and Impacts on Maternal and Perinatal Outcomes between the First Two Waves of the Pandemic. J Pers Med. 2021 Jun 25;11(7):599. doi: 10.3390/jpm11070599. PMID: 34201923.

Study 739 – maternal mortality ratio in Mexico in 2021

The MMR increased from expected, 29.8 per 100,000, to observed 47.2 per 100,000 (click here or study). A 60% increase compared with the pre-pandemic trend. 309 deaths were directly caused by Covid. Citation: Mendez-Dominguez, N., Santos-Zaldívar, K., Gomez-Carro, S. et al. Maternal mortality during the COVID-19 pandemic in Mexico: a preliminary analysis during the first year. BMC Public Health 21, 1297 (2021). https://doi.org/10.1186/s12889-021-11325-3 important

Study 738 – 7 cases from China

Pregnant women with COVID-19 from January 28 to February 28, 2020, at Tongji and Union Hospital, Huazhong University of Science and Technology, Wuhan. (click here or study). This is grid.412793.a, so these cases have been reported many times before. Citation: Liang Dong, Shiyao Pei, Qin Ren, Shuxiang Fu, Liang Yu, Hui Chen, Xiang Chen, Mingzhu Yin, Evaluation of vertical transmission of SARS-CoV-2 in utero: Nine pregnant women and their newborns, Placenta, Volume 111, 2021, Pages 91-96, ISSN 0143-4004, https://doi.org/10.1016/j.placenta.2021.06.007. (https://www.sciencedirect.com/science/article/pii/S0143400421001806)

5 July 2021 – studies 735 to 737 added

Study 737 – 725 cases and 1,459 controls collected by the Intercovid group

A slightly expanded, and different analysis, of the cases in study 683 (click here or study). Citation: Papageorghiou AT, Deruelle P, Gunier RB, et al. Preeclampsia and COVID-19: results from the INTERCOVID prospective longitudinal study [published online ahead of print, 2021 Jun 26]. Am J Obstet Gynecol. 2021;S0002-9378(21)00561-5. doi:10.1016/j.ajog.2021.05.014

Study 736 – 12,566 severe cases from Brazil

Pregnancy cases and non-pregnant control women with severe Covid-19 collected by the Brazilian ARDS Surveillance System (click here or study). Likely overlap with many previous reports from that registry. Citation: Scheler, C.A., Discacciati, M.G., Vale, D.B., Lajos, G.J., de Castro Surita, F. and Teixeira, J.C. (2021), Mortality in pregnancy and the postpartum period in women with severe acute respiratory distress syndrome related to COVID-19 in Brazil, 2020. International Journal of Gynecology & Obstetrics. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13804

Study 735 – case report from Romania

From Premiere Hospital, Timişoara, which has not previously reported cases (click here or study). Citation: Popescu, D.E.; Cioca, A.; Muresan, C.; Navolan, D.; Gui, A.; Pop, O.; Marcovici, T.; Ilie, C.; Craina, M.; Boia, M. A Case of COVID-19 Pregnancy Complicated with Hydrops Fetalis and Intrauterine Death. Medicina 2021, 57, 667. https://doi.org/10.3390/medicina57070667

1 July 2021 – studies 733 and 734 added

Study 734 – 16 cases from Israel

From E. Wolfson Medical Center, in Holon, which has not previously reported cases (click here or study). Citation: Barber, E.; Kovo, M.; Leytes, S.; Sagiv, R.; Weiner, E.; Schwartz, O.; Mashavi, M.; Holtzman, K.; Bar, J.; Engel, A.; Ginath, S. Evaluation of SARS-CoV-2 in the Vaginal Secretions of Women with COVID-19: A Prospective Study. J. Clin. Med. 2021, 10, 2735. https://doi.org/10.3390/jcm10122735

Study 733 – 40 cases from Greece

From Alexandra Maternity Hospital, Athens, which has not previously reported cases (click here or study). No mothers required intensive care and no mothers or babies died. Citation: Antsaklis P, Tasias K, Psarris A, Theodora M, Daskalakis G, Rodolakis A. Covid-19 and pregnancy: the experience of a tertiary maternity hospital. J Perinat Med. 2021 Jun 29. doi: 10.1515/jpm-2021-0070. Epub ahead of print. PMID: 34187133.

29 June 2021 – studies 731 and 732 added

Study 732 – 62 cases from Indonesia

From Universitas Airlangga Hospital, Surabaya, between April & August 2020 (click here or study). Six mothers and five babies died. This hospital has not previously reported cases. Citation: Muhammad Ilham Aldika Akbar, Khanisyah Erza Gumilar, Rino Andriya, Manggala Pasca Wardhana, Pungky Mulawardhana, Jimmy Yanuar Anas, Ernawati, Muhammad Ardian Cahya Laksana, Gustaaf Dekker. Clinical Manifestations and Pregnancy Outcomes of Covid-19 in Indonesian Referral Hospital in Central Pandemic Area medRxiv 2021.06.20.21259219; doi: https://doi.org/10.1101/2021.06.20.21259219. 7 November update. Peer reviewed publication (click here or study). Citation:Akbar MIA, Gumilar KE, Andriya R, Wardhana MP, Mulawardhana P, Anas JY, Ernawati, Laksana MAC, Dekker PG. Clinical manifestations and pregnancy outcomes of COVID-19 in indonesian referral hospital in central pandemic area. Obstet Gynecol Sci. 2021 Nov 5. doi: 10.5468/ogs.21135. Epub ahead of print. PMID: 34736316.

Study 731 – 94 first trimester cases from USA

Selected from the PRIORITY registry (click here or study). Likely overlap with other US cases. Citation: JACOBY VL, MURTHA A, AFSHAR Y, GAW S, ASIODU I, TOLOSA J, NORTON ME, BOSCARDIN J, FLAHERMAN V, Risk of Pregnancy Loss Prior to 20 weeks Gestation with COVID-19, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.06.080.

26 June 2021 – study 730 added

Study 730 – 24 cases from Germany

From author affiliations, treated in University Medical Centre Hamburg-Eppendorf, Hamburg which has not previously reported cases (click here or study). Clinical details in supplementary material here. Citation: Tallarek AC, Urbschat C, Fonseca Brito L, Stanelle-Bertram S, Krasemann S, Frascaroli G, Thiele K, Wieczorek A, Felber N, Lütgehetmann M, Markert UR, Hecher K, Brune W, Stahl F, Gabriel G, Diemert A, Arck PC. Inefficient Placental Virus Replication and Absence of Neonatal Cell-Specific Immunity Upon Sars-CoV-2 Infection During Pregnancy. Front Immunol. 2021 Jun 3;12:698578. doi: 10.3389/fimmu.2021.698578. PMID: 34149740; PMCID: PMC8211452.

24 June 2021 – studies 725 to 729 added

Study 729 – 195 cases from USA

From the University of Maryland health care system in Baltimore (click here or study). Probable overlap with studies 269, 418 and 669. Citation: Liviu Cojocaru, Myint Noe, Autusa Pahlavan, Alissa Werzen, Hyunuk Seung, Young Chae Jessica Yoo, Patricia Tyson, Shivakumar Narayanan, Shifa Turan, Ozhan M. Turan, Joel V. Chua. Increased Risk of Severe COVID-19 Disease in Pregnancy in a Multicenter Propensity Score-Matched Study. medRxiv 2021.06.18.21258899; doi: https://doi.org/10.1101/2021.06.18.21258899

Study 728 – 55 cases from Iran

From Shahid Mohammadi Hospital, Bandar Abbas, Hormozgan, which has not previously reported cases, between March to November 2020 (click here or study). Citation: Taghavi SA, Heidari S, Jahanfar S, Amirjani S, Aji-Ramkani A, Azizi-Kutenaee M, Bazarganipour F. Obstetric, maternal, and neonatal outcomes in COVID-19 compared to healthy pregnant women in Iran: a retrospective, case-control study. Middle East Fertil Soc J. 2021;26(1):17. doi: 10.1186/s43043-021-00059-2. Epub 2021 Jun 14. PMID: 34149282; PMCID: PMC8202219.

Study 727 – 43 cases from Spain

Collected by the nine hospitals of the GESTACOVID Collaborative Group (click here or study). These are Vall d’Hebron , Barcelona; La Paz, Madrid; Hospital Virgen de la Arrixaca, Murcia; Hospital Universitario Cruces, Bizkaia; Hospital Clínico Universitario Lozano Blesa, Zaragoza; Hospital de Torrejón, Madrid; Hospital Universitario San Cecilio, Granada; Hospital Universitario La Fe, Valencia; and Hospital Universitario Príncipe de Asturias, Madrid. Likely overlap with other Spanish series. Citation: Garcia-Ruiz I, Sulleiro E, Serrano B, Fernandez-Buhigas I, Rodriguez-Gomez L, Sanchez-Nieves D, Anton-Pagarolas A, Esperalba-Esquerra J, Frick MA, Camba F, Navarro-Jimenez A, Fernandez-Hidalgo N, Maiz N, Carreras E, Suy A, GESTACOVID Collaborative Group, Congenital infection of SARS-CoV-2 in live-born neonates: a population-based descriptive study, Clinical Microbiology and Infection, https://doi.org/10.1016/j.cmi.2021.06.016.

Study 726 – 31,253 cases from Mexico

The last of these weekly reports for 2020 from Mexico. 205 women had died (click here or study). [In Spanish] Overlap with study 722. Citation: Health Secretary General Directorate of Epidemiology Epidemiological reports of pregnant and postpartum women studied, suspected of COVID 19 February 22, 2021. Weekly publication by the Directorate of Epidemiological Surveillance of Noncommunicable Diseases. https://www.gob.mx/salud/documentos/informes-epidemiologicos-de-embarazadas-y-puerperas-estudiadas-ante-sospecha-de-covid-19. Accessed 24 June 2021

Study 725 – 104 cases from South Africa

From Ekurhuleni Heath District which includes Johannesburg and Pretoria (click here or study). Six women died. Citation: Jayati Kusari Basu, Lawrence Chauke & Terrance Magoro (2021): Maternal mortality from COVID 19 among South African pregnant women, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2021.1902501

20 June 2021 – studies 723 and 724 added

Study 724 – 10,349 cases from Brazil

The Brazilian Obstetric Observatory included 10,349 pregnant or postnatal women with Covid-19 on 20 June 2021 (click here). 2,281 (16.2%) had died. Citation: Rodrigues A, Lacerda L, Francisco, RPV. ‘Brazilian Obstetric Observatory’ arXiv preprint arXiv:2105.06534 (2021). https://observatorioobstetrico.shinyapps.io/covid_gesta_puerp_br/ Accessed 20 June 2021 Important

Study 723 – methods used by Brazilian Obstetric Observatory

This arXiv preprint includes no primary data but provides background methodology for study 724 (click here or study). Citation: Rodrigues, A. and Lacerda, L. and Francisco, RPV ‘Brazilian Obstetric Observatory’ arXiv preprint arXiv:2105.06534 (2021).

19 June update – studies 720 to 722 added

Study 722 – 220 maternal deaths in Mexico

There were 220 maternal deaths from Covid-19 in Mexico in 2020 (click here or study). Citation: General Directorate of Epidemiology. Informes Semanales para la Vigilancia Epidemiológica de Muertes Maternas 2020. https://www.gob.mx/salud/documentos/informes-semanales-parala-vigilancia-epidemiologica-de-muertes-maternas-2020. Accessed June 19 2021

Study 721 – 36 cases from UK

Collected as part of the Coagulopathy Associated with COVID-19 [CA-COVID-19] study from 12 NHS Trusts between 1st of March and 31st May 2020 (click here or study). Likely overlap with many previous UK series. Citation: Crossette-Thambiah C, Nicholson P, Rajakaruna I, Langridge A, Sayar Z, Perelta MR, Essex S, Oakes R, Mounter P, Lewis S, Dutt T, Scott I, Aung N, Shapiro S, Laffan M, Arachchillage DR. The clinical course of COVID-19 in pregnant versus non-pregnant women requiring hospitalisation: results from the multicentre UK CA-COVID-19 study. Br J Haematol. 2021 Jun 16. doi: 10.1111/bjh.17579. Epub ahead of print. PMID: 34132386.

Study 720 – case report from Germany

A woman with SARS-CoV-2 antibodies, but PCR negative, gave birth to a moderately preterm infant with intracranial bleeding and periventricular leukomalacia as a potential consequence of post-COVID-19 hyperinflammation during pregnancy (click here or study). From author affilation cared for in University Hospital of Würzburg, which has not previously reported cases. Citation: Engert V, Siauw C, Stock A, Rehn M, Wöckel A, Härtel C, Wirbelauer J. Severe Brain Damage in a Moderate Preterm Infant as Complication of Post-COVID-19 Response during Pregnancy. Neonatology. 2021 Jun 14:1-4. doi: 10.1159/000516846. Epub ahead of print. PMID: 34126613.

14 June update – study 719 added

Study 719 – Case report from UK or Ireland

From author affiliations the patient was likely cared for either in Birmingham, UK, or Limerick, Republic of Ireland (click here or study). Citation: Marton T, Hargitai B, Hunter K, Pugh M, Murray P. Massive Perivillous Fibrin Deposition and Chronic Histiocytic Intervillositis a Complication of SARS-CoV-2 Infection. Pediatr Dev Pathol. 2021 Jun 3:10935266211020723. doi: 10.1177/10935266211020723. Epub ahead of print. PMID: 34082613.

13 June update – studies 716 to 718 added

Study 718 – 19 maternal deaths in Brazil

An analysis of maternal deaths and live births in the state of Bahia, from January 1, 2011, to December 31, 2020 (click here or study). The 19 maternal deaths in 2020, which mentioned Covid, may underestimate those caused directly or indirectly by the disease. Citation: de Carvalho-Sauer RCO, Costa MDCN, Teixeira MG, do Nascimento EMR, Silva EMF, Barbosa MLA, da Silva GR, Santos TP, Paixao ES. Impact of COVID-19 pandemic on time series of maternal mortality ratio in Bahia, Brazil: analysis of period 2011-2020. BMC Pregnancy Childbirth. 2021 Jun 10;21(1):423. doi: 10.1186/s12884-021-03899-y. PMID: 34112099. Important

Study 717 – 253 cases from Panama

From the following five hospitals, Complejo Hospitalario “Dr. AAM” Social Security Fund, Santo Tomás
Hospital, José Domingo de Obaldía Hospital in Chiriquí, Luis “Chico” Fábrega Hospital in Veraguas, and San Miguel Arcángel Hospital, none of which have previously reported cases (click here or study). The first report from Panama. Citation: Jaime Sánchez, Jorge Espinosa, Luis Carlos Caballero, B Sara Campana, Arelys Quintero, Carlos Luo, C Jorge Ng, Rafael de Gracia, Paulino Vigil-De Gracia. NEW CORONAVIRUS IN PREGNANT WOMEN. Maternal and perinatal outcomes medRxiv 2021.06.03.21258328; doi: https://doi.org/10.1101/2021.06.03.21258328. Update 5 November. Peer reviewed publication (click here). Citation: Sánchez J, Espinosa J, Caballero LC, Campana BS, Quintero A, Luo C, Ng CJ, de Gracia R, Vigil-De Gracia P. COVID 19 and high pregnancy and perinatal complications in Panama. J Matern Fetal Neonatal Med. 2021 Oct 4:1-4. doi: 10.1080/14767058.2021.1967925. Epub ahead of print. PMID: 34607516.

Study 716 – 418 cases from Denmark

Collected by the Danish National Patient Register and Danish Microbiology Database between March 1 and October 31, 2020 (click here or study). Citation: Anna JM Aabakke, Lone Krebs, Tanja G Petersen, Frank S Kjeldsen, Giulia Corn, Karen Wøjdemann, Mette H Ibsen, Fjola Jonsdottir, Elisabeth Rønneberg, Charlotte S Andersen, Iben Sundtoft, Tine Clausen, Julie Milbak, Lars Burmester, Birgitte Lindved, Annette Thorsen-Meyer, Mohammed R Khalil, Birgitte Henriksen, Lisbeth Jønsson, Lise LT Andersen, Kamilla K Karlsen, Monica L Pedersen, Åse Klemmensen, Marianne Vestgaard, Dorthe Thisted, Manrinder K Tatla, Line S Andersen, Anne-Line Brülle, Arense Gulbech, Charlotte B Andersson, Richard Farlie, Lea Hansen, Lone Hvidman, Anne N Sørensen, Sidsel L Rathcke, Katrine H Rubin, Lone K Petersen, Jan S Jørgensen, Lonny Stokholm, Mette Bliddal. SARS-CoV-2 infection in pregnancy in Denmark – characteristics and outcomes after confirmed infection in pregnancy: a nationwide, prospective, population-based cohort study. medRxiv 2021.06.08.21258480; doi: https://doi.org/10.1101/2021.06.08.21258480 Important. [Control group] Update 8 Sept. Peer reviewed citation: Aabakke AJM, Krebs L, Petersen TG, Kjeldsen FS, Corn G, Wøjdemann K, Ibsen MH, Jonsdottir F, Rønneberg E, Andersen CS, Sundtoft I, Clausen T, Milbak J, Burmester L, Lindved B, Thorsen-Meyer A, Khalil MR, Henriksen B, Jønsson L, Andersen LLT, Karlsen KK, Pedersen ML, Klemmensen Å, Vestgaard M, Thisted D, Tatla MK, Andersen LS, Brülle AL, Gulbech A, Andersson CB, Farlie R, Hansen L, Hvidman L, Sørensen AN, Rathcke SL, Rubin KH, Petersen LK, Jørgensen JS, Stokholm L, Bliddal M. SARS-CoV-2 infection in pregnancy in Denmark-characteristics and outcomes after confirmed infection in pregnancy: A nationwide, prospective, population-based cohort study. Acta Obstet Gynecol Scand. 2021 Aug 31. doi: 10.1111/aogs.14252. Epub ahead of print. PMID: 34467518.

12 June update – study 715 added

Study 715 – 514 cases from India

524 livebirths from 514 mothers, including 8 twins and one triplet pregnancy, collected by the National Registry of pregnant women with COVID-19 in India (PregCovid registry) (click here or study). The hospitals are not named and cases likely overlap with other series from India. Citation: Sushma Malik, MD, Suchitra Surve, MD, Poonam Wade, MD, Santosh Kondekar, MD, Vishal Sawant, MD, Murtuja Shaikh, MD, Periyasamy Kuppusamy, PhD, Ramesh Bharmal, MD, Smita D Mahale, PhD, Deepak N Modi, PhD, Rahul K Gajbhiye, MBBS, PhD, Clinical characteristics, management, and short term outcome of neonates born to mothers with COVID-19 in a tertiary care hospital in India, Journal of Tropical Pediatrics, 2021;, fmab054, https://doi.org/10.1093/tropej/fmab054

7 June update – studies 713 and 714 added

Study 714 – 65 cases from Israel

From eight hospitals, so likely overlap with other Israeli studies (click here or study). Compared with 86 vaccinated pregnant women -see vaccine source 39. Citation: Beharier O, Plitman Mayo R, Raz T, Nahum Sacks K, Schreiber L, Suissa-Cohen Y, Chen R, Gomez-Tolub R, Hadar E, Gabbay-Benziv R, Jaffe Moshkovich Y, Biron-Shental T, Shechter-Maor G, Farladansky-Gershnabel S, Yitzhak Sela H, Benyamini-Raischer H, Sela ND, Goldman-Wohl D, Shulman Z, Many A, Barr H, Yagel S, Neeman M, Kovo M. Efficient maternal to neonatal transfer of antibodies against SARS-CoV-2 and BNT162b2 mRNA COVID-19 vaccine. J Clin Invest. 2021 May 20:150319. doi: 10.1172/JCI150319. Epub ahead of print. PMID: 34014840.

Study 713 – 68 cases from Bangladesh

These women were treated at Dhaka Medical College Hospital from March 15, to August 15, 2020 (click here or study). Two mothers died. This hospital, which disambiguates as Dhaka Medical College and Hospital grid.413674.3, has not previously reported cases. Citation: S. K. Jakaria Been Sayeed, Md. Mujibur Rahman, A. K. M. Humayon Kabir, Md. Moniruzzaman, Reaz Mahmud, Mohammad Abdullah Yusuf, Sabrina Rahman. Clinical, Laboratory Characteristics and Pregnancy Outcome of COVID-19 Patients Admitted in the Largest COVID Dedicated Hospital of Bangladesh. American Journal of Internal Medicine. Vol. 9, No. 1, 2021, pp. 11-16. doi: 10.11648/j.ajim.20210901.12 Cautionary noteAmerican Journal of Internal Medicine is not on PubMed, but is listed as a predatory journal on Beall’s list. The publisher Science Publishing Group has an address in New York City but is actually based in Pakistan (click here).

6 June update – studies 710 to 712 added

Study 712 – 1,347 cases from Spain

Collected by the 78 centers of the Spanish Obstetric Emergency Group between 26 February and 5 November 2020 (click here or study). Includes both the second wave in Spain, and a control group of unaffected women. Likely overlap with many other reports from Spain. Citation: Cruz Melguizo S, de la Cruz Conty ML, Carmona Payán P, Abascal-Saiz A, Pintando Recarte P, González Rodríguez L, Cuenca Marín C, Martínez Varea A, Oreja Cuesta AB, Rodríguez PP, Fernández Buhigas I, Rodríguez Gallego MV, Fernández Alonso AM, López Pérez R, Broullón Molanes JR, Encinas Pardilla MB, Ramírez Gómez M, Gimeno Gimeno MJ, Sánchez Muñoz A, Martínez-Pérez O, On Behalf Of The Spanish Obstetric Emergency Group S O E G. Pregnancy Outcomes and SARS-CoV-2 Infection: The Spanish Obstetric Emergency Group Study. Viruses. 2021 May 7;13(5):853. doi: 10.3390/v13050853. PMID: 34067086; PMCID: PMC8151603. [important]

Study 711 – five cases from Indonesia

From Cipto Mangunkusumo General Hospital, Jakarta, and treated with remdesivir (click here or study). This hospital has not previously reported cases. Citation: Saroyo YB, Rumondang A, Febriana IS, Harzif AK, Irwinda R. Remdesivir Treatment for COVID 19 in Pregnant Patients with Moderate to Severe Symptoms: Serial Case Report. Infect Dis Rep. 2021 May 17;13(2):437-443. doi: 10.3390/idr13020042. PMID: 34067822; PMCID: PMC8162322.

Study 710 – 14 cases from Turkey

From Gungoren Hospital, Istanbul, which has not previously reported cases (click here or study). Citation: Yaman A, Kandemir I, Varkal MA. Infants infected with SARS-CoV-2 and newborns born to mother diagnosed with COVID-19: clinical experience. Ir J Med Sci. 2021 Jun 1:1–6. doi: 10.1007/s11845-021-02662-8. Epub ahead of print. PMID: 34075529; PMCID: PMC8169398.

5 June update – studies 708 and 709 added

Study 709 – 64 cases from Italy

From Sacco Hospital and Buzzi Hospital in Milan, and at San Gerardo Hospital in Monza between March and August 2020 (click here or study). The cases are likely included in the various Lomabardy series. Citation: Chiara Tasca, Roberta Simona Rossi, Silvia Corti, Gaia Maria Anelli, Valeria Savasi, Federica Brunetti, Manuela Cardellicchio, Emilio Caselli, Cristina Tonello, Patrizia Vergani, Manuela Nebuloni, Irene Cetin, Placental pathology in COVID-19 affected pregnant women: A prospective case-control study. Placenta, Volume 110, 2021, Pages 9-15, ISSN 0143-4004, https://doi.org/10.1016/j.placenta.2021.04.002. (https://www.sciencedirect.com/science/article/pii/S0143400421001132)

Study 708 – 55 cases from Israel

These first and second trimester cases were treated at Sheba Medical Center, Tel-Hashomer, between March 2020 and February 2021 (click here or study). Possible overlap with studies 330 and 449. Citation: Rosen H, Bart Y, Zlatkin R, Ben-Sira L, Ben Bashat D, Amit S, Cohen C, Regev-Yochay G, Yinon Y. Fetal and Perinatal Outcome Following First and Second Trimester COVID-19 Infection: Evidence from a Prospective Cohort Study. J Clin Med. 2021 May 16;10(10):2152. doi: 10.3390/jcm10102152. PMID: 34065646; PMCID: PMC8156528.

29 May update – studies 706 and 707 added

Study 707 – 120 cases from Palestine

Collected by the Palestine Ministry of Health (click here or study). One mother died. The first reported cases from Palestine. Citation: Maraqa B, Al-Shakhra K, Alawneh M, Jallad R, Alkaila M. Demographic factors associated with COVID-19-related death in Palestine. Public Health Pract (Oxf). 2021 Nov;2:100145. doi: 10.1016/j.puhip.2021.100145. Epub 2021 May 18. PMID: 34027510; PMCID: PMC8129786.

Study 706 – 288 cases from Saudi Arabia

From King Fahad Medical City, Al-Yammamah, and Imam Abdulrahman Al-Faisal hospitals in Riyadh between March and November 2020 (click here or study). One mother and four babies died. This series likely includes cases in studies 554 and 608. Citation: Al-Matary A, Almatari F, Al-Matary M, AlDhaefi A, Alqahtani MHS, Alhulaimi EA, AlOtaiby S, Almehiny K, John LS, Alanazi FS, Azad A, Aldandan FK. Clinical outcomes of maternal and neonate with COVID-19 infection – Multicenter study in Saudi Arabia. J Infect Public Health. 2021 Apr 20;14(6):702-708. doi: 10.1016/j.jiph.2021.03.013. Epub ahead of print. PMID: 34020209; PMCID: PMC8056848.

28 May update – study 705 added

Study 705 – 28 pregnant women in Recovery immune plasma trial

Twenty eight pregnant women participated in the UK Recovery convalescent plasms trial (click here or study). Their group allocation was not reported. Citation: RECOVERY Collaborative Group. Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial. Lancet. 2021 May 14:S0140-6736(21)00897-7. doi: 10.1016/S0140-6736(21)00897-7. Epub ahead of print. PMID: 34000257; PMCID: PMC8121538.

27 May update – study 704 added

Study 704 – 52 cases from Japan

A web-survey of 624 hospitals in Japan identified 52 newborns born to mothers with confirmed SARS-CoV-2 infection (click here or study). One newborn tested positive. Citation: Morioka I, Toishi S, Kusaka T, Wada K, Mizuno K; committee of neonatal medicine in Japan Pediatric Society. Medical care of newborns born to mothers with confirmed or suspected severe acute respiratory syndrome coronavirus 2 infections in Japan. Pediatr Int. 2021 May 27. doi: 10.1111/ped.14855. Epub ahead of print. PMID: 34041810.

24 May update – studies 702 and 703 added

Study 703 – 198 cases from Spain

From author affiliations collected by 11 pathology departments in Barcelona (click here or study). Probably overlap with studies 140, 185, 191, 235, 413, 417, 607, 635, and 695. Citation: Garrido-Pontnou, M., Navarro, A., Camacho, J. et al. Diffuse trophoblast damage is the hallmark of SARS-CoV-2-associated fetal demise. Mod Pathol (2021). https://doi.org/10.1038/s41379-021-00827-5

Study 702 – 7,950 cases from USA

Collected by the SET-NET consortium (click here or study). Citation: Romeo R Galang, Suzanne M Newton, Kate R Woodworth, Isabel Griffin, Titilope Oduyebo, Christina L Sancken, Emily O’Malley Olsen, Kathryn Aveni, Heather Wingate, Hanna Shephard, Chris Fussman, Zahra S Alaali, Kristin Silcox, Samantha Siebman, Umme-Aiman Halai, Camille Delgado Lopez, Mamie Lush, Ayomide Sokale, Jerusha Barton, Ifrah Chaudhary, Paul H Patrick, Levi Schlosser, Bethany Reynolds, Nicole Gaarenstroom, Sarah Chicchelly, Jennifer S Read, Leah de Wilde, Deborah Mbotha, Eduardo Azziz-Baumgartner, Aron J Hall, Van T Tong, Sascha Ellington, Suzanne M Gilboa, CDC COVID-19 Response Pregnancy and Infant Linked Outcomes Team, Risk factors for illness severity among pregnant women with confirmed SARS-CoV-2 infection – Surveillance for Emerging Threats to Mothers and Babies Network, 22 state, local, and territorial health departments, March 29, 2020 -March 5, 2021, Clinical Infectious Diseases, 2021;, ciab432, https://doi.org/10.1093/cid/ciab432

21 May update – study 701 added

Study 701 – 3,527 cases from UK

3,527 women who gave birth between 29th May 2020 and 31st 29 January 2021, and had a positive SARS-Cov-2 test, were compared with 338,553 women giving birth without (click here or study). They were identified using Hospital Episode Statistics, and will therefore overlap with UKOSS and most other UK reports over this time period. Citation: Ipek GUROL-URGANCI, Jennifer E. JARDINE, Fran CARROLL, Tim DRAYCOTT, George DUNN, Alissa FREMEAUX, Tina HARRIS, Jane HAWDON, Edward MORRIS, Patrick MULLER, Lara WAITE, Kirstin WEBSTER, Jan VAN DER MEULEN, Asma KHALIL. Maternal and perinatal outcomes of pregnant women with SARS-CoV-2 infection at the time of birth in England: national cohort study. American Journal of Obstetrics and Gynecology,
2021. ISSN 0002-9378, https://doi.org/10.1016/j.ajog.2021.05.016. (https://www.sciencedirect.com/science/article/pii/S0002937821005652)
[important]

17 May update – study 700 added

Study 700 – 73 cases from USA

From MedStar Washington Hospital Center, Washington, District of Columbia. (click here or study). Citation: Chornock R, Iqbal SN, Wang T, Kodama S, Kawakita T, Fries M. Incidence of Hypertensive Disorders of Pregnancy in Women with COVID-19. Am J Perinatol. 2021 May 3. doi: 10.1055/s-0041-1727167. Epub ahead of print. PMID: 33940651.

16 May update – studies 697 to 699 added. Study 533 updated

Study 699 – 20 cases from China

From Tongji Hospital in Wuhan between January 19 to April 20, 2020 (click here or study). Likely previously reported many times. Citation: Chen G, Liao Q, Ai J, Yang B, Bai H, Chen J, Liu F, Cao Y, Liu H and Li K (2021) Immune Response to COVID-19 During Pregnancy. Front. Immunol. 12:675476. doi: 10.3389/fimmu.2021.675476

Study 698 – 8,248 cases from Brazil

From the Brazilian official severe acute respiratory syndrome (SARS) surveillance system (click here or study). 803 mothers died. Likely overlap with studies 66, 138, 194, 201, 203, 248, 249 and 309. Citation: Maíra L S Takemoto, Marcos Nakamura-Pereira, Mariane O Menezes, Leila Katz, Roxana Knobel, Melania M R Amorim, Carla B Andreucci. Higher case fatality rate among obstetric patients with COVID-19 in the second year of pandemic in Brazil: do new genetic variants play a role? medRxiv 2021.05.06.21256651; doi: https://doi.org/10.1101/2021.05.06.21256651

Study 697 – 145 cases from USA

Treated in a public healthcare system, in Santa Clara County, California from April 15, 2020 to March 31, 2021 (click here or study). Citation: Song D, Prahl M, Gaw SL, et al. Passive and active immunity in infants born to mothers with SARS-CoV-2 infection during pregnancy: Prospective cohort study. Preprint. medRxiv. 2021;2021.05.01.21255871. Published 2021 May 3. doi:10.1101/2021.05.01.21255871 10 July update. Peer reviewed publication (click here or study). Citation: Song D, Prahl M, Gaw SL, et al. Passive and active immunity in infants born to mothers with SARS-CoV-2 infection during pregnancy: prospective cohort study. BMJ Open 2021;11:e053036. doi: 10.1136/bmjopen-2021-053036

15 May update – studies 693 to 696 added

Study 696 – case report from USA

From Cedars‐Sinai Medical Center, Los Angeles, California (click here or study). Citation: Rushakoff JA, Polyak A, Caron J, et al. A case of a pregnant patient with COVID‐19 infection treated with emergency c‐section and extracorporeal membrane oxygenation. J Card Surg. 2021;1‐4. https://doi.org/10.1111/jocs.15623

Study 695 – two cases from Belgium

From author affiliations probably treated at Ghent University Hospital which has not previously reorted cases (click here or study). Citation: Libbrecht S, Van Cleemput J, Vandekerckhove L, Colman S, Padalko E, Verhasselt B, Van de Vijver K, Dendooven A, Dehaene I, Van Dorpe J. A rare but devastating cause of twin loss in a near-term pregnancy highlighting the features of severe SARS-CoV-2 placentitis. Histopathology. 2021 May 13. doi: 10.1111/his.14402. Epub ahead of print. PMID: 33982813.

Study 694 – 60 cases from Spain

This MedRxiv preprint describes lack of virus and presence of antibodies in breast milk (click here or study). Participants were recruited from 7 health centers from Valencia, Barcelona, Granada, and Zaragoza from April to December 2020 Citation: Christine Bauerl, Walter Randazzo, Gloria Sanchez, Marta Selma-Royo, Elia Garcia-Verdevio, Laura Martinez-Rodriguez, Anna Parra-Llorca, Carles Lerin, Victoria Fumado, Francesca Crovetto, Fatima Crispi, Francisco Jose Perez-Cano, Gerardo Rodriguez, Gema Ruiz-Redondo, Cristina Campoy, Cecilia Martinez-Costa, Maria Carmen Collado. SARS-CoV-2 RNA and antibody detection in human milk from a prospective multicenter study in Spain. medRxiv 2021.05.06.21256766; doi: https://doi.org/10.1101/2021.05.06.21256766

Study 693 – 1,062 cases from USA

Cases and controls collected from the Premier Healthcare Database, an all-payer data repository that captures 20% of U.S. hospitalizations (click here or study). Citation: Pineles BL, Goodman KE, Pineles L, O’Hara LM, Nadimpalli G, Magder LS, Baghdadi JD, Parchem JG, Harris AD. In-Hospital Mortality in a Cohort of Hospitalized Pregnant and Nonpregnant Patients With COVID-19. Ann Intern Med. 2021 May 11. doi: 10.7326/M21-0974. Epub ahead of print. PMID: 33971101.

4 May update – study 692 added

Study 692 – case report from the Netherlands

From Amsterdam Medical Centre (AMC) (click here or study). Citation: van Amesfoort JE, Werter DE, Painter RC, Hermans FJR. Severe metabolic ketoacidosis as a primary manifestation of SARS-CoV-2 infection in non-diabetic pregnancy. BMJ Case Rep. 2021 Apr 19;14(4):e241745. doi: 10.1136/bcr-2021-241745. PMID: 33875510.

3 May update – studies 690 and 691 added

Study 691 – 2,824 cases from Canada

The 3rd report from the CanCovid registry includes cases up to 31 December 2020 (click here or study). 1,880 cases reported in detail. Overlap with studies 510 and 690. Citation: Deborah Money. CANADIAN SURVEILLANCE OF COVID-19 IN PREGNANCY: EPIDEMIOLOGY, MATERNAL AND INFANT OUTCOMES Report #3: Released February 25, 2021. School of Population & Public Health, University of British Colombia

Study 690 – 1,940 cases from Canada

The 2nd report from the CanCovid registry includes cases up to 30 November 2020 (click here or study). 1,271 cases repoted in detail. Overlap with study 510. Citation: Deborah Money. CANADIAN SURVEILLANCE OF COVID-19 IN PREGNANCY: EPIDEMIOLOGY, MATERNAL AND INFANT OUTCOMES Report #2: Released January 15, 2021. School of Population & Public Health, University of British Colombia

1 May update – study 689 added

Study 689 – no hospital-acquired maternal infection in New York

Of 72 SARS-CoV-2 negative pregnant women admitted to New York Presbyterian Hospital/Columbia University Irving Medical Center between November 23, 2020 to March 3, 2021, none retested positive during their admission (click here or study). Citation: Zork NM, Markan A, Sheen J-J, AUBEY J, Saiman L, Goffman D, Serial Surveillance for SARS-CoV-2 in hospitalized antepartum women, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.04.222.

29 April update – study 688 added

Study 688 – 2,286 cases from Sweden

Collected from the National Swedish Pregnancy Register between March 11, 2020, and January 31, 2021 (click here or study). Baby outcomes compared with babies of all SARS-CoV-2 negative mothers, and with a matched control group. Probable overlap with studies 20, 88, 259b, 282, 298, 523, 588, 610 and 636. Citation: Norman M, Navér L, Söderling J, et al. Association of Maternal SARS-CoV-2 Infection in Pregnancy With Neonatal Outcomes. JAMA. Published online April 29, 2021. doi:10.1001/jama.2021.5775 [important]

28 April update – studies 686 & 687 added

Study 687 – case report from Japan

From Toho University Omori Medical Center, Tokyo, which has not previously reported cases (click here or study). Citation: Ito A, Hayata E, Nakata M, Shigeta T, Nakamura Y, Kishi K, Yoda H, Morita M. Rapid recovery achieved by intensive therapy after preterm cesarean section for worsening COVID-19-induced acute respiratory failure: A case report and literature review. Case Rep Womens Health. 2021 Apr;30:e00315. doi: 10.1016/j.crwh.2021.e00315. Epub 2021 Apr 18. PMID: 33898274; PMCID: PMC8053357.

Study 686 – 105 cases from Spain

Collected from hospitals participating in the GESNEO-COVID cohort between 15 March & 31 July 2020 (click here or study). The hospitals include General Universitario Gregorio Marañón; Hospital Universitario Infanta Sofía; Hospital La Fe; Hospital Materno Infantil de Badajoz; Complejo Hospitalario de Navarra; Hospital Universitario de Albacete; Hospital Universitario Infanta Elena; Hospital Parc Taulí ; Hospital Universitario HM Montepríncipe; Hospital General de Albace; Complejo Hospitalario de Navarra; Hospital Universitario Infanta Leonor; Hospital San Pedro de Alcántara; Complejo Hospitalario de Santiago, and Hospital 12 de Octubre. Only the last appears to have previously reported cases. However that hospital in Madrid has reported cases in studies 151, 165, 196, 205, 458, 470, 583 and 635. Citation: Carrasco I, Muñoz-Chapuli M, Vigil-Vázquez S, Aguilera-Alonso D, Hernández C, Sánchez-Sánchez C, Oliver C, Riaza M, Pareja M, Sanz O, Pérez-Seoane B, López J, Márquez E, Domínguez-Rodríguez S, Hernanz-Lobo A, De León-Luis JA, Sánchez-Luna M, Navarro ML. SARS-COV-2 infection in pregnant women and newborns in a Spanish cohort (GESNEO-COVID) during the first wave. BMC Pregnancy Childbirth. 2021 Apr 26;21(1):326. doi: 10.1186/s12884-021-03784-8. PMID: 33902483.

24 April update – studies 684 & 685 added, 610 updated, & numbering from 650 corrected

Study 685 – 240 cases from Mexico

Cared for at Instituto Nacional de Perinatologı´a Isidro Espinosa de los Reyes, (INPer), in Mexico City, between April 22 and May 25, 2020 (click here or study). This hospital has not previously reported cases although they likely overlap with other multicentre Mexican series. Citation: Cardona-Pérez JA, Villegas-Mota I, Helguera-Repetto AC, Acevedo-Gallegos S, Rodríguez-Bosch M, Aguinaga-Ríos M, Coronado-Zarco I, León-Juárez M, Aguilar-Ayala D, Valdespino-Vázquez MY, Moreno-Verduzco ER, Rivera MA, Valencia-Contreras C, Gómez-Sousa ML, Solis-Paredes M, Frías-Madrid B, Velasco-Téllez C, Rodriguez-Aldama JC, Avila-Sosa V, Galván-Contreras R, Figueroa-Damian R, Cortés-Bonilla M, Estrada-Gutierrez G, Espino-Y-Sosa S, Irles C. Prevalence, clinical features, and outcomes of SARS-CoV-2 infection in pregnant women with or without mild/moderate symptoms: Results from universal screening in a tertiary care center in Mexico City, Mexico. PLoS One. 2021 Apr 22;16(4):e0249584. doi: 10.1371/journal.pone.0249584. PMID: 33886590.

Study 684 – 250 cases from USA

255 neonates born to 250 mothers with Covid-19 between March 1 and July 31, 2020 (click here or study). Cared for at 11 hospitals in Massachusetts (Baystate; Beth Israel Deaconess; Beverly; Brigham & Women’s; Boston Medical Center; Cambridge Health Alliance; Massachusetts General; Newton-Wellesley; Tufts Children’s; UMass Memorial; Winchester). Probable overlap with studies 142, 231, 257, 262, 387, 488, 490, 519, 531, 550, 571, 577, 589, 591 and 606. Citation: Angelidou A, Sullivan K, Melvin PR, Shui JE, Goldfarb IT, Bartolome R, Chaudhary N, Vaidya R, Culic I, Singh R, Yanni D, Patrizi S, Hudak ML, Parker MG, Belfort MB. Association of Maternal Perinatal SARS-CoV-2 Infection With Neonatal Outcomes During the COVID-19 Pandemic in Massachusetts. JAMA Netw Open. 2021 Apr 1;4(4):e217523. doi: 10.1001/jamanetworkopen.2021.7523. PMID: 33890989.

22 April update – study 683 added

Study 683 –  706 cases & 1,424 controls from the Intergrowth-21 consortium

For each case, two control pregnancies were selected (click here or study). Collected from 43 institutions in 18 countries. Although some institutions had previously reported cases, the authors “excluded women/neonates from the final analysis if their data were already published in any comparative study with women without COVID-19 diagnosis”, and list the overlapping papers. These are studies 92, 102, 140, 144, 150, 161, 232, 246, 252 and 488. Citation: Villar J, Ariff S, Gunier RB, et al. Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study. JAMA Pediatr. Published online April 22, 2021. doi:10.1001/jamapediatrics.2021.1050 [important]

21 April update – study 682 added

Study 682 – case report from Germany

A pregnant woman with Covid-19 deteriorated post-partum and required ventilation and ECMO (click here or study). From author affiliations she was cared for at Vivantes Klinikum im Friedrichshain in Berlin, which has not previously reported cases. Citation: Maier JT, Zickler D, Metz M, Jebens A, Jarchau U, Fischer J, Kimmel V, Prueter E, Hellmeyer L. Peripartum Covid-19 Pneumonia with Severe ARDS – A Case Report. Z Geburtshilfe Neonatol. 2021 Apr;225(2):183-187. doi: 10.1055/a-1365-9262. Epub 2021 Apr 19. PMID: 33873231.

18 April update – studies 676 to 681 added

Study 681 – 72 cases from USA

Cared from at Boston Medical Center, Massachusetts (click here or study). Probable overlap with studies 292 and 490. Citation: Sabharwal V, Bartolome R, Hassan SA, Levesque BM, Camelo IY, Wachman EM, Figueira M, Yarrington CD, Cooper ER, Barnett ED, Parker MG. Mother-Infant Dyads with COVID-19 at an Urban, Safety-Net Hospital: Clinical Manifestations and Birth Outcomes. Am J Perinatol. 2021 Apr 14. doi: 10.1055/s-0041-1726429. Epub ahead of print. PMID: 33853145.

Study 680 – case report from USA

Cared for at University of California, Los Angeles (click here or study). Citation: Mok T, Contreras D, Chmait RH, Goldstein J, Pluym ID, Tabsh K, Aldrovandi G, Afshar Y. Complicated Monochorionic-Diamniotic Twins in a Pregnant Woman with COVID-19 in the Second Trimester. Am J Perinatol. 2021 Apr 14. doi: 10.1055/s-0041-1726428. Epub ahead of print. PMID: 33853148.

Study 679 – 56 cases from USA

Cared from at Kings County Hospital Center in New York, which has not previously reported cases (click here or study). Citation: Liu C, Andrusier M, Silver M, Applewhite L, Clare CA. Effect of SARS-CoV-2 Infection on Pregnancy Outcomes in an Inner-City Black Patient Population. J Community Health. 2021 Apr 15:1–7. doi: 10.1007/s10900-021-00988-z. Epub ahead of print. PMID: 33855649; PMCID: PMC8046575.

Study 678 – 34 patients from Turkey

Cared for at Kartal Training and Research Hospital, Istanbul, which has not previously reported cases (click here or study). Citation: Ozer KB, Sakin O, Koyuncu K, Cimenoglu B, Demirhan R. Comparison of Laboratory and Radiological Findings of Pregnant and Non-Pregnant Women with Covid-19. Rev Bras Ginecol Obstet. 2021 Mar;43(3):200-206. doi: 10.1055/s-0041-1726054. Epub 2021 Apr 15. PMID: 33860503.

Study 677 – 1,609 cases from USA

The Cerner COVID-19 De-Identified Data Cohort was used to compare pregnant women with Covid, with non-pregnant affected women aged 18-44 (click here or study). Although pregnant women were more likely to be hospitalised, they were no more likely to need invasive ventilation or die. They were cared for in 62 US hospitals with which Cerner had a data use agreement. Citation: Qeadan F, Mensah NA, Tingey B, Stanford JB. The risk of clinical complications and death among pregnant women with COVID-19 in the Cerner COVID-19 cohort: a retrospective analysis. BMC Pregnancy Childbirth. 2021 Apr 16;21(1):305. doi: 10.1186/s12884-021-03772-y. PMID: 33863292.

Study 676 – 18 cases from from Ireland

Cared for at Rotunda Hospital, Dublin (click here or study). Probable overlap with studies 284, 300 and 596. Citation: Alaya F, Worrall AP, O’toole F, Doyle J, Duffy RM, Geary MP. Health-related quality of life and quality of care in pregnant and postnatal women during the COVID-19 pandemic: A cohort study. Int J Gynaecol Obstet. 2021 Apr 16. doi: 10.1002/ijgo.13711. Epub ahead of print. PMID: 33864252.

16 April update – studies 674 and 675 added

Study 675 – 38 severe cases in UK

7/34 ECMO referrals of women aged 16-49 to the Royal Brompton Hospital in London in the first wave, were pregnant or post-partum, compared with 31/62 in the second wave (click here or study). This hospital has not previously reported cases, but there will be overlap with the various UKOSS and ICNARC reports. Citation: Suraj Kadiwar, Jonathan J Smith, Stephane Ledot, Mark Johnson, Paolo Bianchi, Natasha Singh, Claudia Montanaro, Michael Gatzoulis, Nishel Shah, Emem-Fong Ukor, Were pregnant women more affected by COVID-19 in the second wave of the pandemic?, The Lancet, 2021, ISSN 0140-6736, https://doi.org/10.1016/S0140-6736(21)00716-9. https://www.sciencedirect.com/science/article/pii/S0140673621007169)

Study 674 – 525 first wave cases from Italy

Collected by the Italian Obstetric Surveillance System (ITOSS) registry between 25 February and 31 July 2020 (click here or study). Likely overlap with study 536 and other Italian series. Citation: Donati, S.; Corsi, E.; Salvatore, M.A.; Maraschini, A.; Bonassisa, S.; Casucci, P.; Cataneo, I.; Cetin, I.; D’Aloja, P.; Dardanoni, G.; De Ambrosi, E.; Ferrazzi, E.; Fieni, S.; Franchi, M.P.; Gargantini, G.; Iurlaro, E.; Leo, L.; Liberati, M.; Livio, S.; Locci, M.; Marozio, L.; Martini, C.; Maso, G.; Mecacci, F.; Meloni, A.; Mignuoli, A.D.; Patanè, L.; Pellegrini, E.; Perotti, F.; Perrone, E.; Prefumo, F.; Ramenghi, L.; Rusciani, R.; Savasi, V.; Schettini, S.C.A.; Simeone, D.; Simeone, S.; Spinillo, A.; Steinkasserer, M.; Tateo, S.; Ternelli, G.; Tironi, R.; Trojano, V.; Vergani, P.; Zullino, S.; on behalf of the ItOSS COVID-19 Working Group. Childbirth Care among SARS-CoV-2 Positive Women in Italy. Int. J. Environ. Res. Public Health 2021, 18, 4244. https://doi.org/10.3390/ijerph18084244

15 April update – study 673 added

Study 673 – 75 cases from USA

The placentas were compared with those from 75 control pregnancies (click here or study). From author affiliations the patients had been cared for at Columbia University Irving Medical Center, New York. Citation: Debelenko L, Katsyv I, Chong AM, Peruyero L, Szabolcs M, Uhlemann AC. Trophoblast damage with acute and chronic intervillositis: disruption of the placental barrier by severe acute respiratory syndrome coronavirus 2. Hum Pathol. 2021 Mar;109:69-79. doi: 10.1016/j.humpath.2020.12.004. Epub 2020 Dec 13. PMID: 33321162; PMCID: PMC7733682.

14 April update – studies 671and 672 added

Study 672 – 50 cases from USA

From Loma Linda University Medical Center which has not previously reported cases (click here or study). Citation: Ruofan Yao, Courtney B Martin , Victoria S Haase , Beverly C Tse , Ms Melissa Nishino , Ciprian Gheorghe , Kevin Balli , Initial clinical characteristics of gravid SARS-CoV-2 positive patients and the risk of progression to severe COVID-19 disease, American Journal of Obstetrics & Gynecology MFM (2021), doi:https://doi.org/10.1016/j.ajogmf.2021.100365

Study 671 – 29 cases from Spain

From University Hospital La Paz, Madrid (click here or study). Probable overlap with study 196. Citation: Blasco Santana L, Miraval Wong E, Álvarez-Troncoso J, Sánchez García L, Bartha JL, Regojo-Zapata RM. Maternal and perinatal outcomes and placental pathologic examination of 29 SARS-CoV-2 infected patients in the third trimester of gestation. J Obstet Gynaecol Res. 2021 Apr 5. doi: 10.1111/jog.14784. Epub ahead of print. PMID: 33821521.

13 April update – studies 668 to 670 added

Study 670 – 110 cases from Iran

Collected between March and October 2020 from multiple hospitals in Tehran (click here or study). Five women died. Citation: Vizheh M, Muhidin S, Aghajani F, Maleki Z, Bagheri F, Hosamirudsari H, Aleyasin A, Tehranian A. Characteristics and outcomes of COVID-19 pneumonia in pregnancy compared with infected nonpregnant women. Int J Gynaecol Obstet. 2021 Apr 8. doi: 10.1002/ijgo.13697. Epub ahead of print. PMID: 33829492.

Study 669 – 1,454 cases from USA

From the Society for Obstetric Anesthesia and Perinatology (SOAP) COVID-19 Registry (click here or study). Collected from March 19-May 31, 2020 from 14 centres which, from author affiliations, probably include Brigham and Women’s Hospital, Boston; Weill Cornell, New York; Massachusetts General Hospital, Boston; University of California at San Francisco; Langone Health, New York, Stanford University School of Medicine, Emory School of Medicine, Atlanta, Icahn School of Medicine at Mount Sinai, New York; Mayo Clinic, Rochester; University of Maryland School of Medicine, Baltimore; Washington University School of Medicine, St. Louis; MGH-North Shore Medical Center, Danvers; Columbia University College of Physicians and Surgeons, New York. Citation: Katz D, Bateman BT, Kjaer K, Turner DP, Spence NZ, Habib AS, George RB, Toledano RD, Grant G, Madden HE, Butwick AJ, Lynde G, Minehart RD, Beilin Y, Houle TT, Sharpe EE, Kodali B, Bharadwaj S, Farber MK, Palanisamy A, Prabhu M, Gonzales NY, Landau R, Leffert L. The Society for Obstetric Anesthesia and Perinatology (SOAP) COVID-19 Registry: An analysis of outcomes among pregnant women delivering during the initial SARS-CoV-2 outbreak in the United States. Anesth Analg. 2021 Apr 8. doi: 10.1213/ANE.0000000000005592. Epub ahead of print. PMID: 33830956.

Study 668 – two cases from Chile

Two patients with severe Covid-19 were pregnant in this series of patients cared for in the Regional Hospital in Los Ríos (click here or study). Both were in the 2nd trimester. One was delivered by Caesarean at 28 weeks. This hospital has not previously reported cases. Citation: Olivares F, Muñoz D, Fica A, Delama I, Alvarez I, Navarrete M, Blackburn E, Garrido P, Wenger R, Grandjean J. Clinical features of 47 patients infected with COVID-19 admitted to a Regional Reference Center. Rev Med Chil. 2020 Nov;148(11):1577-1588. doi: 10.4067/S0034-98872020001101577. PMID: 33844763.

12 April update – studies 662 to 667 added

Study 667 – 5,479 cases from UK

This paper was prepared by the ISARIC4C Consortium, UK Obstetric Surveillance System (UKOSS) and COVID-19 Clinical Information Network (CO-CIN) for the UK Scientific Advisory Group for Emergencies (SAGE). It includes pregnant women with Covid from the whole of the UK. It is available as a pdf (click here or study) and as a set of powerpoint slides (click here or study). Citation: Marian Knight, Rema Ramakrishnan, Kathryn Bunch, Nicola Vousden, Jennifer J Kurinczuk, Sarah Dunn, Lisa Norman, Aisling Barry, Ewen Harrison, Annemarie Docherty, Calum Semple. Females in Hospital with SARS-CoV-2 infection, the association with pregnancy and pregnancy outcomes: A UKOSS/ISARIC/CO-CIN investigation. Report presented 25 March 2021. Published 9 April 2021 https://www.gov.uk/government/publications/ukossisaricco-cin-females-in-hospital-with-sars-cov-2-infection-the-association-with-pregnancy-and-pregnancy-outcomes-25-march-2021 Accessed 12 April 2021 [important]

Study 666 – 165 cases from Brazil

The patients were cared for in three different unnamed hospitals in São Paulo (click here or study). They may overlap with cases in studies 201, 213 and 426. Citation: Kiappe OP, Santos da Cruz NF, Rosa PAC, Arrais L, Bueno de Moraes NS. Ocular Assessments of a Series of Newborns Gestationally Exposed to Maternal COVID-19 Infection. JAMA Ophthalmol. Published online April 07, 2021. doi:10.1001/jamaophthalmol.2021.1088

Study 665 – 567 cases from Iran

Eight women died (click here or study). They were all cared for at Forghani Hospital in Qom. If this is the same as Nekouei-Hedayati-Forghani Hospital in the same city, some may have been reported in study 555. Neither hospital disambiguates on GRID.ac. Citation: Samadi, P., Alipour, Z., Ghaedrahmati, M. and Ahangari, R. (2021), The severity of COVID‐19 among pregnant women and the risk of adverse maternal outcomes. International Journal of Gynecology & Obstetrics. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13700

Study 664 – case report from Iran

Cared for at Firoozgar Hospital, Tehran (click here or study). The patient died, so may be included in study 345. Citation: Goudarzi, S, Firouzabadi, FD, Mahmoudzadeh, F, Aminimoghaddam, S. Pulmonary embolism in pregnancy with COVID‐19 infection: A case report. Clin Case Rep. 2021; 00: 1– 5. https://doi.org/10.1002/ccr3.3709

Study 663 – 68 cases from USA

This BioRxiv preprint reports a detailed study of placental immunology (click here or study). The hospitals caring for the patients are not reported, but from the last author affiliation might be Massachusetts General Hospital in Boston. Citation: Evan A Bordt, Lydia L Shook, Caroline Atyeo, Krista M Pullen, Rose M De Guzman, Marie-Charlotte Meinsohn, Maeva Chauvin, Stephanie Fischinger, Laura J. Yockey, Kaitlyn James, Rosiane Lima, Lael M Yonker, Alessio Fasano, Sara Brigida, Lisa M Bebell, Drucilla J Roberts, David Pépin, Jun R Huh, Staci D Bilbo, Jonathan Z Li, Anjali Kaimal, Danny Schust, Kathryn J Gray, Douglas Lauffenburger, Galit Alter, Andrea G Edlow. Sexually dimorphic placental responses to maternal SARS-CoV-2 infection bioRxiv 2021.03.29.437516; doi: https://doi.org/10.1101/2021.03.29.437516

Study 662 – 13 cases from China

Collected from centres outside Wuhan (click here or study). Some or all have probably been reported previously. Citation: Yangli Liu , Haihong Chen , Weiping Tan , Yukun Kuang , Kejing Tang , Yifeng Luo , Yubiao Guo , Clinical characteristics and outcome of SARS-CoV-2 infection during pregnancy, Journal of Infection (2021), doi: https://doi.org/10.1016/j.jinf.2021.03.030

11 April update – studies 658 to 661 added

Study 661 – 246 cases from Spain

Collected from the 45 hospitals of the Spanish Obstetric Emergency group (click here or study). Likely overlap with studies 264b, 548 and 589 as well as other Spanish report. Citation: Martinez-Perez O, Prats Rodriguez P, Muner Hernandez M, Encinas Pardilla MB, Perez Perez N, Vila Hernandez MR, Villalba Yarza A, Nieto Velasco O, Del Barrio Fernandez PG, Forcen Acebal L, Orizales Lago CM, Martinez Varea A, Muñoz Abellana B, Suarez Arana M, Fuentes Ricoy L, Martinez Diago C, Janeiro Freire MJ, Alférez Alvarez-Mallo M, Casanova Pedraz C, Alomar Mateu O, Lesmes Heredia C, Wizner de Alva JC, Bernardo Vega R, Macia Badia M, Alvarez Colomo C, Sanchez Muñoz A, Pratcorona Alicart L, Alonso Saiz R, Lopez Rodriguez M, Del Carmen Barbancho Lopez M, Meca Casbas MR, Vaquerizo Ruiz O, Moran Antolin E, Nuñez Valera MJ, Fernandez Fernandez C, Tubau Navarra A, Cano Garcia AM, Baena Luque C, Soldevilla Perez S, Gastaca Abasolo I, Adanez Garcia J, Teulon Gonzalez M, Puertas Prieto A, Ostos Serna R, Del Pilar Guadix Martin M, Catalina Coello M, Ferriols Perez E, Caño Aguilar A, De la Cruz Conty ML, Sainz Bueno JA; Spanish Obstetric Emergency Group. The association between SARS-CoV-2 infection and preterm delivery: a prospective study with a multivariable analysis. BMC Pregnancy Childbirth. 2021 Apr 1;21(1):273. doi: 10.1186/s12884-021-03742-4. PMID: 33794829; PMCID: PMC8016158.

Study 660 – 22 cases from USA

From Johns Hopkins Hospital, Baltimore, which has not previously reported cases (click here or study). Citation: Sherer ML, Lei J, Creisher P, Jang M, Reddy R, Voegtline K, Olson S, Littlefield K, Park HS, Ursin RL, Ganesan A, Boyer T, Elsayed N, Brown DM, Walch SN, Antar AAR, Manabe YC, Jones-Beatty K, Christopher Golden W, Satin AJ, Sheffield JS, Pekosz A, Klein SL, Burd I. Pregnancy alters IL-1β expression and anti-viral antibody responses during SARS-CoV-2 infection. Am J Obstet Gynecol. 2021 Mar 30:S0002-9378(21)00208-8. doi: 10.1016/j.ajog.2021.03.028. Epub ahead of print. PMID: 33798476; PMCID: PMC8008823.

Study 659 – case report from Italy

A woman with Covid-19 and twins cared for at the Institute for Maternal and Child Health “IRCCS Burlo Garofolo”, Trieste (click here or study). This hospital has not previously reported cases. Citation: Trombetta A, Comar M, Tommasini A, Canton M, Campisciano G, Zanotta N, Cason C, Maso G, Risso FM. SARS-CoV-2 Infection and Inflammatory Response in a Twin Pregnancy. Int J Environ Res Public Health. 2021 Mar 17;18(6):3075. doi: 10.3390/ijerph18063075. PMID: 33802696; PMCID: PMC8002573.

Study 658 – 30 cases from Italy

From Policlinico Umberto I Hospital, Sapienza University of Rome (click here or study). This hospital appears to have only reported one previous case in study 448. Citation: Porpora MG, Merlino L, Masciullo L, D’Alisa R, Brandolino G, Galli C, De Luca C, Pecorini F, Fonsi GB, Mingoli A, Franchi C, Oliva A, Manganaro L, Mastroianni CM, Piccioni MG. Does Lung Ultrasound Have a Role in the Clinical Management of Pregnant Women with SARS COV2 Infection? Int J Environ Res Public Health. 2021 Mar 9;18(5):2762. doi: 10.3390/ijerph18052762. PMID: 33803223; PMCID: PMC7967479.

3 April update – studies 654 to 657 added

Study 657 – case report from Iran

Neurosurgical complications from Covid-19 in pregnancy are described (click here or Saberi case rep). From author affiliations the patient was cared for, and delivered by Caesarean, in Imam Khomeini hospital, Tehran, which has not previously reported cases. Citation: Saberi H, et al, Acute presentation of third ventricular cavernous malformation following COVID-19 infection in a pregnant woman: A case report, Neurochirurgie, https://doi.org/10.1016/j.neuchi.2021.03.010

Study 656 – case report from Japan

From author affiliations the patient who required ventilation, but recovered was probably cared for at University of the Ryukyus Hospital, Okinawa, which has not previously reported cases (click here or Chinen case rep). Citation: Y. Chinen, Y. Kinjyo, K. Mekaru, et al., Critical respiratory failure in pregnancy complicated with COVID-19: A case report, Case Reports in Women’s Health (2018), https://doi.org/10.1016/j.crwh.2021.e00309

Study 655 – 45 cases from Canada

From author affiliations the women were cared for at McGill University Health Centre, and Jewish General Hospital Montreal (click here or Trahan Montreal). Citation: Marie-Julie Trahan, Isabelle Malhame, Patrick O’Farrell, Cristina Mitric, Jade Desilets, Marie-Pier Bastrash, Amira El-Messidi, Haim A. Abenhaim, Obstetrical and Newborn Outcomes among Patients with SARS-CoV-2 during Pregnancy, Journal of Obstetrics and Gynaecology Canada (2021),
doi: https://doi.org/10.1016/j.jogc.2021.03.012

Study 654 – 458 cases from Chile

From Hospital San Jose, Santiago, 8 April – 30 August 2020 (click here or Haye Chile). One mother died. A different hospital Study 486, which has not previously reported cases. Citation: Maria Teresa Haye, Giorgia Cartes, Jorge Gutiérrez, Paz Ahumada, Bernardo Krause, Mario Merialdi & Rogelio Gonzalez (2021): Maternal and perinatal outcomes in pregnant women with confirmed severe and mild COVID-19 at one large maternity hospital in Chile, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2021.1902498

30 March update – studies 652 and 653 added

Study 653 – 64 cases from Egypt

This MedRxiv preprint includes 64 pregnant women, of whom three died (click here or paper). Citation: Noha Asem, Mohamed Hassany, Khaled Taema, Hossam Masoud, Gehan Elassal, Ehab Kamal, Wagdy Amin, Akram Abdelbary, Amin Abdel Baki, Samy Zaky, Ahmad Abdalmohsen, Hamdy Ibrahim, Mohamed Elnady, Ahmed Mohamed, Ehab Atteia, Hala Zaid. Demographic and clinical features associated with in-hospital mortality in Egyptian COVID-19 patients: A retrospective cohort study. medRxiv 2021.03.22.21253577; doi: https://doi.org/10.1101/2021.03.22.21253577

Study 652 – 708 cases from Norway

This MedRxiv preprint includes 708 pregnant women with a positive test from the Norwegian National Population Registry between March 1st, 2020 and February 28th, 2021 (click here or paper). Citation: Maria C. Magnus, Laura Oakley, Håkon K. Gjessing, Olof Stephansson, Hilde M. Engjom, Ferenc Macsali, Petur B. Juliusson, Anne-Marie Nybo Andersen, Siri E. Håberg. Pregnancy and risk of COVID-19. medRxiv 2021.03.22.21254090; doi: https://doi.org/10.1101/2021.03.22.21254090

21 March update – study 651 added

Study 651 – 2 cases in two US fertility clinics

Both asymptomatic (click here or PIIS0002937821001599). Six other women, out of 339 showed evidence of past infection. The clinics were Utah Fertility Center, Utah, and Boston IVF, Massachusetts. Citation: FOULK R, SAKKAS D, KAYALI R, VALBUENA D, SIMON C, CUZZI J, SARSCoV-2 immunity, infective and naïve incidence in fertility clinics after lockdown, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.03.008.&nbsp;

20 March update – studies 648 to 650 added

Study 650 – 132 cases from India

Cared for between 15th May and 15th November 2020, at Tata Main Hospital, Jamshedpur, which has not previously reported cases (click here or cureus-0013-00000013184). Citation: Singh V, Choudhary A, Datta MR, Ray A. Maternal and Neonatal Outcomes of COVID-19 in Pregnancy: A Single-Centre Observational Study. Cureus. 2021 Feb 6;13(2):e13184. doi: 10.7759/cureus.13184. PMID: 33717728; PMCID: PMC7943051.

Study 649 – Case report from USA

The authors are affiliated with the Medical College of Wisconsin, Milwaukee, Wisconsin (click here or e240385.full). The clinical details differ from the case in study 563. Citation: Roddy JT, Collier WS, Kurman JS. Prone positioning for severe ARDS in a postpartum COVID-19 patient following caesarean section. BMJ Case Rep. 2021 Mar 16;14(3):e240385. doi: 10.1136/bcr-2020-240385. PMID: 33727296.

Study 648 – one case from UK

From 7 May to 6 June 2020, 1/465 asymptomatic pregnant women from The Rosie Hospital in Cambridge tested positive (click here or s12884-021-03653-4). The Rosie has not previously reported cases. Citation: Xu R, Pauley TA, Missfelder-Lobos H, Haddon RJ, Gupta RK, Chong HP. Samba II PCR testing for COVID-19 in pregnant women: a retrospective cohort study and literature review. BMC Pregnancy Childbirth. 2021 Mar 17;21(1):212. doi: 10.1186/s12884-021-03653-4. PMID: 33731037.

16 March – study 647 added

Study 647 – 36 cases from UK

This MedRxiv preprint from ICNARC, QResearch, and the COVID-19 testing (PHE) database, reports 36 pregnant or recently pregnant women in critical care with Covid-19, between 1 November 2020 and 27 January 2021, of whom 25 were infected with the variant of concern (VOC) B.1.1.7 (click here or 2021.03.11.21253364v1.full). Citation: Martina Patone, Karen Thomas, Rob Hatch, Pui San Tan, Carol Coupland, Weiqi Liao, Paul Mouncey, David Harrison, Kathryn Rowan, Peter Horby, Peter Watkinson, Julia Hippisley-Cox Analysis of severe outcomes associated with the SARS-CoV-2 Variant of Concern 202012/01 in England using ICNARC Case Mix Programme and QResearch databases. medRxiv 2021.03.11.21253364; doi: https://doi.org/10.1101/2021.03.11.21253364

13 March update – study 646 added. Full text added to study 576

Study 646 – Case report from UK

Cared for at East and North Hertfordshire NHS Trust, Stevenage, in April 2020 (click here or e238055.full). Likely included in studies 533, 539 and perhaps others. Citation: Reindorf M, Newman J, Ingle T. Successful use of CPAP in a pregnant patient with COVID-19 pneumonia. BMJ Case Rep. 2021 Mar 8;14(3):e238055. doi: 10.1136/bcr-2020-238055. PMID: 33685910; PMCID: PMC7942271.

8 March update – studies 642 to 645 added. Study 541, English version added

Study 645 – case report from Brazil

From author affiliations she was probably cared for at the Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, which has not previously reported cases (click here or fmed-08-624166). Citation JAK B, Zanirati G, Rodrigues FVF, et al. Case Report: Placental Maternal Vascular Malperfusion Affecting Late Fetal Development and Multiorgan Infection Caused by SARS-CoV-2 in Patient With PAI-1 4G/5G Polymorphism. Front Med (Lausanne). 2021;8:624166. Published 2021 Feb 17. doi:10.3389/fmed.2021.624166

Study 644 – 17 serologically positive cases from Italy

It is not clear which Turin hospital cared for these patients (click here or diagnostics-11-00398). They may therefore overlap with those in studies 79, 167, 195, 247 and 615. Citation: Cosma S, Carosso AR, Borella F, Cusato J, Bovetti M, Bevilacqua F, Carosso M, Gervasoni F, Sciarrone A, Marozio L, Revelli A, Rolfo A, Filippini C, Ghisetti V, Di Perri G, Benedetto C. Prenatal Biochemical and Ultrasound Markers in COVID-19 Pregnant Patients: A Prospective Case-Control Study. Diagnostics (Basel). 2021 Feb 26;11(3):398. doi: 10.3390/diagnostics11030398. PMID: 33652805.

Study 643 – case report from USA

Cared for at McGovern Medical School, University of Texas Health Science Center, Houston (click here or cureus-0013-00000012990). May be included in study 267b. Citation: Moses ML, Kazzi NG, Lee L. Severe Thrombocytopenia in a Pregnant Patient with Asymptomatic COVID-19 Infection: A Case Report. Cureus. 2021 Jan 29;13(1):e12990. doi: 10.7759/cureus.12990. PMID: 33654642; PMCID: PMC7916745.

Study 642 – 142 cases from USA

Cared for at New York Presbyterian, Brooklyn Methodist Hospital between March and August 2020 (click here or Zhang JMFM Feb 28 14767058.2021). Probably included in a number of New York series. Citation: Peilin Zhang, Taryn Heyman, Marisa Greechan, Beata Dygulska, Farah Al Sayyed, Pramod Narula & Sanford Lederman (2021) Maternal, neonatal and placental characteristics of SARS-CoV-2 positive mothers, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2021.1892637

7 March update – Study 641 added

Study 641 – 50 cases from Italy

From Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, so likely included in the various series from there and Lombardy  (click here or jog.14729). Citation: D’Ambrosi F, Iurlaro E, Tassis B, Di Maso M, Erra R, Cetera GE, Cesano N, Di Martino D, Ossola MW, Ferrazzi EM. Sociodemographic characteristics of pregnant women tested positive for COVID-19 admitted to a referral center in Northern Italy during lockdown period. J Obstet Gynaecol Res. 2021 Mar 1. doi: 10.1111/jog.14729. Epub ahead of print. PMID: 33650278.

6 March update – study 640 added

Study 640 – 54 cases from Turkey

54 pregnant women with Covid-19 cared for in Ankara City Hospital between August 1 and October 1, 2020 (click here or [full text not yet available]). Likely overlap with studies 203, 223, 399, 512, 569 and 604. Citation: Ayhan SG, Tanacan A, Atalay A, Sinaci S, Tokalioglu EO, Sahin D, Tekin OM. Assessment of fetal Doppler parameters in pregnant women with COVID-19 infection: a prospective case-control study. J Perinat Med. 2021 Mar 3. doi: 10.1515/jpm-2020-0512. Epub ahead of print. PMID: 33660492.

4 March update – studies 638 and 639 added

Study 639 – 5,963 cases from USA

This MedRxiv preprint includes pregnant women testing positive for SARS-CoV-2 identified though the Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET) between March 29, and January 8, 2021 (click here or 2021.02.27.21252169v1.full). They likely overlap with those in study 338Citation: Romeo R. Galang, Suzanne M. Newton, Kate R. Woodworth, Isabel Griffin, Titilope Oduyebo, Christina L. Sancken, Emily O’Malley Olsen, Kathy Aveni, Heather Wingate, Hanna Shephard, Chris Fussman, Zahra S. Alaali, Samantha Siebman, Umme-Aiman Halai, Camille Delgado Lopez, Jerusha Barton, Mamie Lush, Paul H. Patrick, Levi Schlosser, Ayomide Sokale, Ifrah Chaudhary, Bethany Reynolds, Similoluwa Sowunmi, Nicole Gaarenstroom, Jennifer S. Read, Sarah Chicchelly, Leah de Wilde, Eduardo Azziz-Baumgartner, Aron J. Hall, Van T. Tong, Sascha Ellington, Suzanne M. Gilboa Risk factors for illness severity among pregnant women with confirmed SARS-CoV-2 infection – Surveillance for Emerging Threats to Mothers and Babies Network, 20 state, local, and territorial health departments, March 29, 2020 -January 8, 2021 CDC COVID-19 Response Pregnancy and Infant Linked Outcomes Team medRxiv 2021.02.27.21252169; doi: https://doi.org/10.1101/2021.02.27.21252169

Study 638 – 83 cases from USA

From Barnes-Jewish Hospital in St. Louis, Missouri between June 1, and November 30, 2020 (click here or Rosenbloom AJOG PIIS0002937821001502). They likely overlap with cases in studies 69, 259, 290 and possibly 579. Citation: Rosenbloom JI, Raghuraman N, Carter EB, Kelly JC, COVID-19 Infection and Hypertensive Disorders of Pregnancy, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.03.001.

2 March update – studies 636 and 637 added

Study 637 – case report from USA

The hospital is not named, but the authors are affiliated with the Whole Family Health Center, Vero Beach, Florida, which has not previously reported cases (click here or 1-s2.0-S2214911221000059-main). Citation: Poisson TM, Pierone G Jr. Placental pathology and fetal demise at 35 weeks of gestation in a woman with SARS-CoV-2 infection: A case report. Case Rep Womens Health. 2021 Apr;30:e00289. doi: 10.1016/j.crwh.2021.e00289. Epub 2021 Jan 28. PMID: 33527073; PMCID: PMC7840395.

Study 636 – case report from Sweden

Probably included in study 610 (click here or Zaigham case BJOG in press). Although cared for at either Lund or Malmo hospitals clinical details differ from cases in studies 259b and 588. Citation: Zaigham M, Holmberg A, Karlberg ML, Lindsjö OK, Jokubkiene L, Sandblom J, Strand AS, Andersson O, Hansson SR, Nord DG, Tannenberg P. Intrauterine vertical SARS-CoV-2 infection: a case confirming transplacental transmission followed by divergence of the viral genome. BJOG. 2021 Feb 27. doi: 10.1111/1471-0528.16682. Epub ahead of print. PMID: 33638908.

28 February update – study 635 added

Study 635 – 12 cases from Spain 

From author affiliations they were cared for at Vall d’Hebron Hospital, Barcelona, and Hospital Universitario “12 de Octubre”, Madrid, between 1 March and 31 April 2020 (click here or ). They probably overlap with cases in studies 151, 165, 185, 205, 413, 417, 458, 470 and 583. Citation: Jiménez-Lozano I, Caro-Teller JM, Fernández-Hidalgo N, Miarons M, Frick MA, Batllori Badia E, Serrano B, Parramon-Teixidó CJ, Camba-Longueira F, Moral-Pumarega MT, San Juan-Garrido R, Cabañas Poy MJ, Suy A, Gorgas Torner MQ. Safety of tocilizumab in COVID-19 pregnant women and their newborn: A retrospective study. J Clin Pharm Ther. 2021 Feb 26. doi: 10.1111/jcpt.13394. Epub ahead of print. PMID: 33638257.

27 February update – studies 628 to 634 added

Study 634 – 13 cases from Spain

These 13 pregnant women with Covid-19 were cared for at five public hospitals in Valencia (Hospital Universitario de La Ribera, Hospital Lluis Alcanyis, Hospital de Ontinyent, Hospital General de Valencia and Hospital Universitari i Politècnic La Fe), none of which have previously reported cases (click here or 1-s2.0-S1130862121000334-main). They may of course be included in Spanish or international registries. Spanish, with English abstract. Citation: R. Vila-Candel, D. Mena-Tudela, A. Gómez-Seguí et al., Manejo del parto, el puerperio y la lactancia en mujeres positivas para SARS-CoV-2. Estudio multicéntrico en la Comunidad Valenciana, Enfermería Clínica, https://doi.org/10.1016/j.enfcli.2021.01.006

Study 633 – 58 cases from USA

These pregnant women with Covid-19  were cared for at the University of Iowa Hospitals and Clinics, which have not previously reported cases (click here or Steffen Iowa AJP s-0041-1723938). However the woman reported in study 537 is probably also in this series. Citation: Steffen HA, Swartz SR, Jackson JB, Kenne KA, Ten Eyck PP, Merryman AS, Castaneda CN, Marsden K, Maxwell T, Merrill AE, Krasowski MD, Rysavy MB. SARS-CoV-2 Infection during Pregnancy in a Rural Midwest All-delivery Cohort and Associated Maternal and Neonatal Outcomes. Am J Perinatol. 2021 Feb 21. doi: 10.1055/s-0041-1723938. Epub ahead of print. PMID: 33611783.

Study 632 – 583 cases from Mexico

This report (click here or excli2021-3413) of 395,343 patients with COVID-19 in 688 medical units in Mexico City between February 24 and September 14, 2020, includes 583 pregnant women, of whom 10 died. See supplementary tables 3, 8 and 15 for pregnancy data excli2021-3413_supplementary_information. They likely overlap with cases reported in studies 271, 340, 425, 475, 513 and 518. Citation: Mancilla-Galindo, J., García-Méndez, J. Óscar, Marquéz-Sánchez, J., Reyes-Casarrubias, R. E. ., Aguirre-Aguilar, E., Rocha-González, H. I., & Kammar-García, A. (2021). All-cause mortality among patients treated with repurposed antivirals and antibiotics for COVID-19 in Mexico City: A real-world observational study. EXCLI Journal, 20, 199-222. https://doi.org/10.17179/excli2021-3413

Study 631 – case report from China

Cared for in March 2020 in Peking (Beijing) University Third Hospital grid.411642.4 (click here or JCTH-9-133). This hospital has not previously reported cases and does not seem to be included in the various non-Wuhan China series. Citation: Li QY, An ZY, Li C, et al. Chronic Active Hepatitis B with COVID-19 in Pregnancy: A Case Report. J Clin Transl Hepatol. 2021;9(1):133-135. doi:10.14218/JCTH.2020.00085

Study 630 – 81 cases from Turkey

55/81 with chest X ray or CT are reported (click here or JTGGA-0-0-En). From author affiliations they were cared for in Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, and Marmara University Faculty of Medicine, both in Istanbul. The cases may therefore overlap with those in studies 146, 210, 244 and 286. Citation: Kuzan TY, Murzoğlu Altıntoprak K, Çiftçi HÖ, Kuzan BN, Yassa M, Tuğ N, Çimşit NÇ. Clinical and radiologic characteristics of symptomatic pregnant women with COVID-19 pneumonia. J Turk Ger Gynecol Assoc. 2021 Feb 26. doi: 10.4274/jtgga.galenos.2021.2020.0215. Epub ahead of print. PMID: 33631874.

Study 629 – 45 cases from USA

Of these 45 cases from Einstein Medical Center Philadelphia, three re-tested positive more than 90 days later (click here or 1-s2.0-S2589933321000264-main). Probably includes the case reported in study 320. Citation: Emily Dubelbeiss, Michael Silverberg, Chase White, David Jaspan, Christopher Haines, Jay Goldberg, Repeat positive SARS-CoV-2 (COVID-19) testing e 90 days apart in pregnant women., American Journal of Obstetrics & Gynecology MFM (2021), doi: https://doi.org/10.1016/j.ajogmf.2021.100331

Study 628 – 887 cases from WAPM

These cases collected from 76 centers in 25 countries, and diagnosed between 04 April & 28 October 2020 overlap with those in studies 278 and 415 and other studies (click here or 1-s2.0-S2589933321000240-main). The centres can be inferred from author affilations, but case numbers by centre are not reported.  Citation: Francesco D’Antonio, Cihat Sen, Daniele DI Mascio, et al. Maternal and perinatal outcomes in high vs low risk-pregnancies affected by SARS-COV-2 infection (Phase-2): The WAPM (World Association of Perinatal Medicine) working group on COVID-19, American Journal of Obstetrics & Gynecology MFM (2021), doi: https://doi.org/10.1016/j.ajogmf.2021.100329

23 February update – study 539 (UK PanCovid & US AAP SONPM registries) updated

21 February update – studies 619 to 627 added

Study 627 – 49 cases from Italy

From Università di Roma Tor Vergata, from September to November 2020 (click here or aogs.14130). Citation: Rizzo, G., Mappa, I., Maqina, P., Bitsadze, V., Khizroeva, J., Makatsarya, A. and D’Antonio, F. (2021), Effect of SARS‐CoV‐2 infection during the second half of pregnancy on fetal growth and hemodynamics: a prospective study. Acta Obstetricia et Gynecologica Scandinavica. Accepted Author Manuscript. https://doi.org/10.1111/aogs.14130 [case series & controls, 2nd wave]

Study 626 – 247 cases from Germany

Collected from 65 hospitals participating in the CRONOS registry between 3 April and 1 October 2020 (click here or CRONOS). 14 women were treated in ITU. No maternal deaths were reported, although 32 women have not yet recovered. Of 189 completed pregnancies, there were 4 terminations, 2 stillbirths and 183 livebirths. Four neonates were infected but all recovered. Although German cases were included in studies 127 and 278 this is the first substantive report from Germany. Citation: Pecks U, Kuschel B, Mense L, Oppelt P, Rüdiger M, on behalf of the CRONOS network: Pregnancy and SARS-CoV-2 infection in Germany—the CRONOS registry. Dtsch Arztebl Int 2020; 117: 841–2. DOI: 10.3238/arztebl.2020.0841 [important]

Study 625 – case report from USA

From MedStar Washington Hospital Center, Washington DC (click here or 10-1055-s-0040-1721672). The clinical details differ from those in study 21 from the same hospital. Citation: Mokhtari NB, Drassinower D, Orr LA, Cobb NK, Mims OL Jr, Landy HJ. Expectant Management of Severe COVID-19 Pneumonia in Late Preterm Pregnancy and Subsequent Cholecystitis: Lessons Learned. AJP Rep. 2021;11(1):e29-e33. doi:10.1055/s-0040-1721672

Study 624 – 4 cases from India

Of four pregnant women with Covid-19 in pregnancy treated in Bundelkhand Medical College Hospital, Sagar City, one died (click here or jog.14696). This hospital has not previously reported cases. Citation: Rawat, S.K., Saad, T., Jindal, A. and Vyas, A.K. (2021), Coronavirus disease 2019 in pregnancy: Case report on maternal death in Sagar City of Central India. J. Obstet. Gynaecol. Res.. https://doi.org/10.1111/jog.14696

Study 623 – Case report from Japan

From Kyoto Prefectural University of Medicine, which as not previously reported cases (click here or jog.14701). Citation: Waratani, M., Ito, F., Tanaka, Y., Mabuchi, A., Mori, T. and Kitawaki, J. (2021), Severe coronavirus disease pneumonia in a pregnant woman at 25 weeks’ gestation: A case report. J. Obstet. Gynaecol. Res.. https://doi.org/10.1111/jog.14701

Study 622 – Case report from Iran

From Arash Hospital, Tehran University of Medical Sciences, Tehran (click here or Rabiei JMCR). The clinical features and hospital suggest these are the same triplets as previously reported in studies 250 and 409. Citation: Rabiei, M., Soori, T., Abiri, A. et al. Maternal and fetal effects of COVID-19 virus on a complicated triplet pregnancy: a case report. J Med Case Reports 15, 87 (2021). https://doi.org/10.1186/s13256-020-02643-y

Study 621 –  Case report from Turkey

From Konya Education and Research Hospital, Konya, which has not previously reported cases (click here or Gunduz). Citation: GUNDUZ, Zahide Betül. Venous sinus thrombosis during COVID-19 infection in pregnancy: a case report. Sao Paulo Med. J. [online]. In press. [cited 2021-02-21], pp.-. Available from: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802021005005202&lng=en&nrm=iso&gt;. Epub Feb 15, 2021. ISSN 1806-9460. https://doi.org/10.1590/1516-3180.2020.0659.r1.08122020.

Study 620 – 17 cases from Brazil

Of 360 women aged <20 with Covid-19 in Pernambuco, from March 12 to June 19, 2020, 17 were pregnant or in the puerperium (click here or [14761645 – The American Journal of Tropical Medicine and Hygiene] Clinical Characteristics and Mortality Profile of COVID-19 Patients Aged less than 20 years Old in Pernambuco – Brazil). None died. Citation: Sena GR, Lima TPF, Vidal SA, Duarte MDCMB, Bezerra PGM, Fonseca Lima EJ, Braga C, Andrade LB, Lins MM, Torres LC, Lima JTO, Mello MJG. Clinical Characteristics and Mortality Profile of COVID-19 Patients Aged less than 20 years Old in Pernambuco – Brazil. Am J Trop Med Hyg. 2021 Feb 18: tpmd201368. doi: 10.4269/ajtmh.20-1368. Epub ahead of print. PMID: 33606669.

Study 619 – 240 cases from USA

From Washington state (click here or Lokken AJOG Feb 21). These appear to be the same cases as in study 573. Citation: LOKKEN EM, TAYLOR GG, HUEBNER EM, VANDERHOEVEN J, HENDRICKSON S, COLER B, SHENG JS, WALKER CL, MCCARTNEY SA, KRETZER NM, RESNICK R, KACHIKIS A, BARNHART N, SCHULTE V, BERGAM B, K K, ALBRIGHT C, LARIOS V, KELLEY L, LARIOS V, EMHOFF S, RAH J, RETZLAFF K, THOMAS C, PAEK BW, HSU RJ, ERICKSON A, CHANG A, MITCHELL T, HWANG JK, GOURLEY R, ERICKSON S, DELANEY S, KLINE CR, ARCHABALD K, BLAIN M, LACOURSE SM, ADAMS WALDORF KM, Higher SARS-CoV-2 Infection Rate in Pregnant Patients, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.02.011.

15 February update – studies 615 to 618 added

Study 618 – 350 cases from India

From Government Medical College Kannur, Pariyaram, in Kerala, which has not previously reported cases (click here or 13224_2021_Article_1436). Two mothers were admitted to ITU, one of whom was ventilated. Of 221 babies 32 tested positive. Citation: Ajith S, Reshmi VP, Nambiar S, Naser A, Athulya B. Prevalence and Risk Factors of Neonatal Covid-19 Infection: A Single-Centre Observational Study. J Obstet Gynaecol India. 2021 Feb 4:1-4. doi: 10.1007/s13224-021-01436-7. Epub ahead of print. PMID: 33564217; PMCID: PMC7861010. [breastfeeding, rooming in]

Study 617 – Case report from Indonesia

A woman with Covid-19 delivered twins at 32 weeks by Caesarean (click here or main (3)). One twin had an ileal perforation. Mother and babies were cared for at Dr. Soetomo General Hospital, Surabaya, which has not previously reported cases. Citation: Harahap A, Harianto A, Etika R, Utomo MT, Angelika D, Handayani KD, Arif Sampurna MT. Spontaneous Ileum Perforation in a premature twin with Coronavirus-19 positive mother. J Pediatr Surg Case Rep. 2021 Feb 4:101807. doi: 10.1016/j.epsc.2021.101807. Epub ahead of print. PMID: 33564621; PMCID: PMC7860962.

Study 616 – 91 cases from USA

From the University of Texas Medical Branch Galveston, Texas which has not previously reported cases (click here or s-0041-1723761). Citation: Berry M, Wang A, Clark SM, Harirah HM, Jain S, Olson GL, Pacheco LD, Saade GR, Saad AF. Clinical Stratification of Pregnant COVID-19 Patients based on Severity: A Single Academic Center Experience. Am J Perinatol. 2021 Feb 6. doi: 10.1055/s-0041-1723761. Epub ahead of print. PMID: 33548937. [case series]

Study 615 – 17 patients with antibodies from Italy

These pregnant women were probably cared for at S. Anna Hospital, Turin (click here or 1-s2.0-S0165037821000152-main). They may therefore overlap with studies 79, 167, 195 and 247. Citation: Stefano Cosma, Andrea Roberto Carosso, Silvia Corcione, Jessica Cusato, Fulvio Borella, Miriam Antonucci, Luca Marozio, Alberto Revelli, Mario Preti, Valeria Ghisetti, Giovanni Di Perri, Chiara Benedetto. Longitudinal analysis of antibody response following SARS-CoV-2 infection in pregnancy: From the first trimester to delivery. Journal of Reproductive Immunology, Volume 144, 2021, 103285, ISSN 0165-0378, https://doi.org/10.1016/j.jri.2021.103285. (https://www.sciencedirect.com/science/article/pii/S0165037821000152) [neonatal antibodies]

13 February update – studies 611 to 614 added

Study 614 – serum screening in Jamaica

From University Hospital of the West Indies, in Kingston, during September-November 2020 (click here or Chisolm preprint). Citation: Te’Anne Chisolm, Jerome P Walker, Ynolde Leys, Tiffany R Butterfield, Candice Medley, Tamara K Thompson, Glendee Reynolds-Campbell, Willem H Mulder, Michelle Campbell Mitchell, Joshua J Anzinger. SARS-CoV-2 Seroprevalence Among Antenatal Clinic Attendees in Kingston, Jamaica, September-November 2020. medRxiv 2021.02.08.21251367; doi: https://doi.org/10.1101/2021.02.08.21251367 [2nd wave]

Study 613 – serum screening in Kenya

From Kenyatta National Hospital in Nairobi between 30th July and 25th August (click here or 2021.02.05.21250735v1.full). Citation: R. Lucinde, D. Mugo, C. Bottomley, R Aziza, J. Gitonga, H. Karanja, J. Nyagwange, J. Tuju, P. Wanjiku, E. Nzomo, E. Kamuri, K. Thuranira, S. Agunda, G. Nyutu, A. Etyang, I. M. O. Adetifa, E. Kagucia, S. Uyoga, M. Otiende, E. Otieno, L. Ndwiga, C. N. Agoti, R. Aman, M. Mwangangi, P. Amoth, K. Kasera, A. Nyaguara, W. Ng’ang’a, L. B. Ochola, E. Barasa, P. Bejon, B. Tsofa, L. I. Ochola-Oyier, G. M. Warimwe, A. Agweyu, J. A. G. Scott, K. E. Gallagher. Sero-surveillance for IgG to SARS-CoV-2 at antenatal care clinics in two Kenyan referral hospitals. medRxiv 2021.02.05.21250735; doi: https://doi.org/10.1101/2021.02.05.21250735

Study 612 – 14 cases from Spain

Interim report of a planned follow-up study (click here or MOACC-19 study 2020.08.20.20178657v2.full). Citation: Javier Llorca, Carolina Lechosa-Muñiz, Pilar Gortázar, María Fernández-Ortiz, Yolanda Jubete, María J. Cabero, the MOACC-19 group, Jéssica Alonso-Molero, Bárbara Arozamena, Laura Conde-Gil, Elsa Cornejo del Río, Rocío Cuesta-González, Trinidad Dierssen-Sotos, Pelayo Frank de Zulueta, Inés Gómez-Acebo, Coral Llano-Ruiz, Lorena Lasarte-Oria, Sonia López-Gómez, Sonia Mateo-Sota, Victoria Orallo, Rosa Pardo, Daniel Pérez González, María Sáez de Adana Herrero. Cohort profile: COVID-19 in a cohort of pregnant women and their descendants, the MOACC-19 study. medRxiv 2020.08.20.20178657; doi: https://doi.org/10.1101/2020.08.20.20178657

Study 611 – ISARIC again

Among 240,149 patients admitted to hospital with covid-19 in the UK, 1,502/17,850 women of childbearing age, were reported as being pregnant (click here or 2020.07.17.20155218v6.full). Citation: Martina Escher, Matthew Hall, J Kenneth Baillie, Joaquin Baruch, Lucille Blumberg, Gail Carson, Barbara Wanjiru Citarella, Emmanuelle Dankwa, Annemarie B Docherty, Murray Dryden, Christl Donnelly, Jake Dunning, Christophe Fraser, Hayley Hardwick, Ewen M Harrison, Karl Holden, Waasila Jassat, Christiana Kartsonaki, Kalynn Kennon, James Lee, Kenneth McLean, Caroline Mudara, Peter JM Openshaw, Daniel R Plotkin, Mark Pritchard, Amanda Rojek, Clark D Russell, Malcolm Gracie Semple, Louise Sigfrid, Susan Smith, Jia Wei, Peter Horby, Piero L Olliaro, Laura Merson. ISARIC COVID-19 Clinical Data Report: 10 February 2021 medRxiv 2020.07.17.20155218; doi: https://doi.org/10.1101/2020.07.17.20155218 [2nd wave]

12 February update – study 610 added

Study 610 – 214 cases from Scandinavia

These cases were collected by the Nordic Obstetric Surveillance Study (NOSS) collaboration countries, Denmark, Finland, Iceland, Norway, Sweden, (click here or 2021.02.05.21250672v1.full). They probably include cases from studies 20, 88, 256, 259b, 278, 282, 298, 299, 341, 523 and 588. Citation: Hilde Engjom, Anna JM Aabakke, Kari Klungsøyr, Teresia Svanvik, Outi Äyräs, Eva Jonasdottir, Lars Thurn, Elin Jones, Karin Pettersson, Lill Trine Nyfløt, Iqbal Al-Zirqi, Siri Vangen, Pétur B. Júlíusson, Karin Källén, Mika Gissler, Lone Krebs. COVID-19 in pregnancy – characteristics and outcomes of pregnant women admitted to hospital because of SARS-CoV-2 infection in the Nordic countries. medRxiv 2021.02.05.21250672; doi: https://doi.org/10.1101/2021.02.05.21250672 [Registry] Update 24 April. Peer reviewed publication (click here or study). Citation: Engjom H, Aabakke AJ, Klungsøyr K, Svanvik T, Äyräs O, Jonasdottir E, Thurn L, Jones E, Pettersson K, Nyfløt LT, Al-Zirqi I, Vangen S, Júlíusson PB, Källén K, Gissler M, Krebs L. COVID-19 in pregnancy – characteristics and outcomes of pregnant women admitted to hospital because of SARS-CoV-2 infection in the Nordic countries. Acta Obstet Gynecol Scand. 2021 Apr 22. doi: 10.1111/aogs.14160. Epub ahead of print. PMID: 33885150.

11 February update – studies 608 and 609 added

Study 609 – 1,291 cases from USA

These pregnant women with a positive SARS-CoV-2 test result were cared for in 33 National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network hospitals between March 1 and July 31, 2020 (click here or METZ Disease_Severity_and_Perinatal_Outcomes_of.121 (1)). The hospitals, listed here, include many which have previously reported cases. Citation: Metz, Torri D. MD, MS; Clifton, Rebecca G. PhD; Hughes, Brenna L. MD; Sandoval, Grecio MA; Saade, George R. MD; Grobman, William A. MD, MBA; Manuck, Tracy A. MD, MS; Miodovnik, Menachem MD; Sowles, Amber BSN, RN; Clark, Kelly BSN, RN; Gyamfi-Bannerman, Cynthia MD, MS; Mendez-Figueroa, Hector MD; Sehdev, Harish M. MD; Rouse, Dwight J. MD; Tita, Alan T.N. MD, PhD; Bailit, Jennifer MD, MPH; Costantine, Maged M. MD; Simhan, Hyagriv N. MD; Macones, George A. MD; for the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Network Disease Severity and Perinatal Outcomes of Pregnant Patients With Coronavirus Disease 2019 (COVID-19), Obstetrics & Gynecology: February 8, 2021 – Volume Latest Articles – Issue – 10.1097/AOG.0000000000004339 doi: 10.1097/AOG.0000000000004339

Study 608 – Case report from Saudi Arabia

From King Saud Medical City, Riyadh (click here or ccr3.3913). None of the newborns reported in study 554 from the same centre tested positive. Citation: Huseynova, RA, A. Bin Mahmoud, L, Huseynov, O, et al. A neonate born to an infected COVID‐19 mother was tested positive just 24 hours after its birth. Clin Case Rep. 2021; 00: 1– 4. https://doi.org/10.1002/ccr3.3913

10th February update – studies 606 and 607 added

Study 607 – 317 cases from Spain

Pregnant women with anti SARS-CoV-2 &/or a positive RT-PCR, from three hospitals (Sant Joan de Déu, Hospital Clinic Barcelona, and Hospital de Sant Pau) in Barcelona (click here or CROVETTO ciab104 (1)). The details and hospitals suggest overlap with study 235. Citation: Francesca Crovetto, Fàtima Crispi, Elisa Llurba, Rosalia Pascal, Marta Larroya, Cristina Trilla, Marta Camacho, Carmen Medina, Carlota Dobaño, Maria Dolores Gomez-Roig, Francesc Figueras, Eduard Gratacos, KidsCorona Pregnancy COVID-19 group, Impact of SARS-CoV-2 Infection on Pregnancy Outcomes: A Population-Based Study, Clinical Infectious Diseases, 2021;, ciab104, https://doi.org/10.1093/cid/ciab104

Study 606 – IgG & IgA in breast milk from 18 cases in USA

The hospitals from which women were recruited is not stated. but from the ethics approvals included centres in Idaho, the University of Rochester Medical Center, New York, and Brigham & Women’s Hospital, Boston, Massachusetts (click here or mBio-2021-Pace-e03192-20.full). Citation: Pace RM, Williams JE, Järvinen KM, Belfort MB, Pace CDW, Lackey KA, Gogel AC, Nguyen-Contant P, Kanagaiah P, Fitzgerald T, Ferri R, Young B, Rosen-Carole C, Diaz N, Meehan CL, Caffé B, Sangster MY, Topham D, McGuire MA, Seppo A, McGuire MK. 2021. Characterization of SARS-CoV-2 RNA, antibodies, and neutralizing capacity in milk produced by women with COVID-19. mBio 12:e03192-20. https://doi.org/10.1128/mBio.03192-20.&nbsp;

9th February update – studies 603 to 605 added

Study 605 – Case report from Qatar

From the Women’s Wellness and Research Center, Hamad Medical Corporation, Doha, which also reported the case in study 577 (click here or ccr3.3886). However the clinical details differ. Citation: Khatib MY, Olagundoye VO, Elshafei MS, El Khatib FM, Mohamed AS, Nashwan AJ. Management considerations for a critically ill 26-gestational week patient with COVID-19: A case report. Clin Case Rep. 2021;00:1–4. https://doi.org/10.1002/ccr3.3886 [ITU, ventilation]

Study 604 – 39 cases from Turkey

Cared for at Ankara City Hospital (click here or full text not available). Likely overlap with studies 203, 227, 244, 399, 444, 512, & 569. Citation: Erol Koç, Esin Merve, Fındık, Rahime Bedir, Akkaya, Hatice, Karadağ, Işılay, Tokalıoğlu, Eda Özden and Tekin, Özlem Moraloğlu. “Comparison of hematological parameters and perinatal outcomes between COVID-19 pregnancies and healthy pregnancy cohort” Journal of Perinatal Medicine, vol. 49, no. 2, 2021, pp. 141-147. https://doi.org/10.1515/jpm-2020-0403 [control group]

Study 603 – 35 cases from Austria

Cared for at Clinik Ottakring, in Vienna, which has not previously reported cases (click here or full text not available). Citation: Hall, Mirijam, Endress, David, Hölbfer, Susanne and Maier, Barbara. “SARS-CoV-2 in pregnancy: maternal and perinatal outcome data of 34 pregnant women hospitalised between May and October 2020” Journal of Perinatal Medicine, vol. 49, no. 2, 2021, pp. 138-140. https://doi.org/10.1515/jpm-2020-0499&nbsp;

7th February update – studies 599 to 602 added

Study 602 – case report from United Arab Emirates

A woman contracted Covid-19 at 26 weeks gestation and required ventilation and five days of ECMO therapy (click here or Tambawala e240823.full). She recovered and the pregnancy is continuing. Cared for at Dubai Hospital, which has not previously reported cases. Citation: Tambawala ZY, Hakim ZT, Hamza LK, et al. Successful management of severe acute respiratory distress syndrome due to COVID-19 with extracorporeal membrane oxygenation during mid-trimester of pregnancy. BMJ Case Reports CP 2021;14:e240823.

Study 601 – 34 cases from USA

Cared for at Hutzel Women’s Hospital, Detroit, Michigan, between March 11, 2020 and July 31, 2020 (click here or 10-1055-s-0040-1721673). This hospital has not previously reported cases. Citation: Jani S, Jacques SM, Qureshi F, et al. Clinical Characteristics of Mother-Infant Dyad and Placental Pathology in COVID-19 Cases in Predominantly African American Population. AJP Rep. 2021;11(1):e15-e20. doi:10.1055/s-0040-1721673

Study 600 – 171 cases from USA

Of 171 pregnant women hospitalised with Covid-19, 21 were admitted to ICU and 3 died (click here or 2021.01.29.21250788v1.full). They were cared for at the University of California affiliated hospitals of Davis, Irvine, Los Angeles, San Diego, and San Francisco, so likely overlap with study 323. Citation: Miriam Nuño, Yury García, Ganesh Rajasekar, Diego Pinheiro, Alec J. Schmidt. COVID-19 Hospitalizations in Five California Hospitals. medRxiv 2021.01.29.21250788; doi: https://doi.org/10.1101/2021.01.29.21250788

Study 599 – 116 seropositive women and 12 RT-PCR positive in USA

Of 708 pregnant women cared for at the Mount Sinai and Mount Sinai West hospitals in New York, from April 20, 2020 and delivered by 15 August, 116 were seropositive, and 12 RT-PCR positive (click here or 2021.02.01.21250943v1.full (1)). They likely overlap with studies 86, 119,131, 135, 160, 240, 412, 455, & 457. Citation: Nina M. Molenaar, Anna-Sophie Rommel, Lotje de Witte, Siobhan M. Dolan, Whitney Lieb, Erona Ibroci, Sophie Ohrn, Jezelle Lynch, Christina Capuano, Daniel Stadlbauer, Florian Krammer, Lauren B. Zapata, Rachel I. Brody, Rhoda S. Sperling, Omara Afzal, Mr Roy Missall, Amy Balbierz, Teresa Janevic, Joanne Stone, Elizabeth A. Howell, Veerle Bergink. Seroprevalence of SARS-CoV-2 during pregnancy and associated outcomes: results from an ongoing prospective cohort study, New York City. medRxiv 2021.02.01.21250943; doi: https://doi.org/10.1101/2021.02.01.21250943

3rd February update – study 598 added

Study 598 – 100 mothers, 101 babies from USA

From New York–Presbyterian’s Morgan Stanley Children’s Hospital and Allen Hospital from March 13 to April 24, 2020 (click here or jamapediatrics_dumitriu_2020_oi_200070_1611604165.97231 (1)). Both hospitals are affiliated with Columbia University Irving Medical Center. The authors note that they include 14 previously reported cases in study 27. There may also be overlap with studies 14, 41, 95, 96, 136, 160, 216, 230, 234, 261, and 276. Citation: Dumitriu D, Emeruwa UN, Hanft E, et al. Outcomes of Neonates Born to Mothers With Severe Acute Respiratory Syndrome Coronavirus 2 Infection at a Large Medical Center in New York City. JAMA Pediatr. 2021;175(2):157–167. doi:10.1001/jamapediatrics.2020.4298

1st February update – studies 592 to 597 added. Study 3 withdrawal noted.

Studies 593 to 597 – SMFM 2021 posters

Posters presented at the Society for Maternal Fetal Medicine virtual conference, 25 to 30 January, 2021 (SMFM 2021). Study 593– 52 patients from McGill University Medical Centre and the Jewish Genereal Hospital, Montreal, Quebec, Canade . Study 594 – 10 cases from University of Toledo, Ohio, USA . Study 595 – 29 cases from University of New Mexico Hospital, Albuquerque, New Mexico, USA . Study 596 – 11 cases from The Rotunda Hospital, Dublin, Ireland . Study 597 – 15 cases (two deaths) from the University of Mississippi Medical Center, Jackson, Mississippi, USA .  Citations to the AJOG abstracts to be added.

Study 592 – Case report from Italy

From Santo Stefano Hospital, Prato (click here or jmv.26609). The clinical features suggest this is case 2 in study 367. Citation: Cavaliere AF, Marchi L, Aquilini D, Brunelli T, Vasarri PL. Passive immunity in newborn from SARS-CoV-2-infected mother. J Med Virol. 2020 Oct 19. doi: 10.1002/jmv.26609. Epub ahead of print. PMID: 33073377.

31 January update – study 589 to 591 added

Study 591 – antibody transfer in 22 mother infant dyads from USA

SARS-CoV-2-specific antibody transfer is reduced compared to influenza- and pertussis-specific antibodies, and cord titers and functional activity is lower than in maternal plasma, in 22 maternal: cord dyads from SARS-CoV-2 positive mothers in third trimester (click here or PIIS0092867420317499). From Boston Massachusetts. Citation: Atyeo C, Pullen KM, Bordt EA, Fischinger S, Burke J, Michell A, Slein MD, Loos C, Shook LL, Boatin AA, Yockey LJ, Pepin D, Meinsohn MC, Nguyen NMP, Chauvin M, Roberts D, Goldfarb IT, Matute JD, James KE, Yonker LM, Bebell LM, Kaimal AJ, Gray KJ, Lauffenburger D, Edlow AG, Alter G. Compromised SARS-CoV-2-specific placental antibody transfer. Cell. 2020 Dec 23:S0092-8674(20)31749-9. doi: 10.1016/j.cell.2020.12.027. Epub ahead of print. PMID: 33476549; PMCID: PMC7755577. [important]

Study 590 – antibody levels in 83 mother/infant dyads from USA

Anti-SARS-CoV-2 IgG crosses the placenta (click here or jamapediatrics_flannery_2021_oi_210002_1611680224.61476). From Pennsylvania Hospital in Philadelphia, so may overlap with studies 65, 175, 202, 221, 350, 359 and 496. Citation: Flannery DD, Gouma S, Dhudasia MB, et al. Assessment of Maternal and Neonatal Cord Blood SARS-CoV-2 Antibodies and Placental Transfer Ratios. JAMA Pediatr. Published online January 29, 2021. doi:10.1001/jamapediatrics.2021.0038 [important]

Study 589 – 1,150 cases from Spain

No association between past flu & Tdap vaccination status, and severity of SARS-CoV-2 in pregnancy (click here or vaccines-09-00031). From the 78 Spanish Obstetric Emergency Group hospitals. Citation: de la Cruz Conty ML, Encinas Pardilla MB, Garcia Sanchez M, Gonzalez Rodriguez L, Muner-Hernando ML, Royuela Vicente A, Pintado Recarte P, Martinez Varea A, Martinez Diago C, Cruz Melguizo S, Martinez-Perez O, On Behalf Of The Spanish Obstetric Emergency Group. Impact of Recommended Maternal Vaccination Programs on the Clinical Presentation of SARS-CoV-2 Infection: A Prospective Observational Study. Vaccines (Basel). 2021 Jan 8;9(1):31. doi: 10.3390/vaccines9010031. PMID: 33429912; PMCID: PMC7826802.

30 January update – studies 582 to 588 added

Study 588 – Case report from Sweden

From either Lund or Malmo (click here or main (13)). The clinical details differ from study 259b. Citation: Kolkova Z, Bjurström MF, Länsberg JK, Svedas E, Hamer MA, Hansson SR, Herbst A, Zaigham M. Obstetric and intensive-care strategies in a high-risk pregnancy with critical respiratory failure due to COVID-19: A case report. Case Rep Womens Health. 2020 Jul 8;27:e00240. doi: 10.1016/j.crwh.2020.e00240. PMID: 32714844; PMCID: PMC7340590.

Study 587 – 0/67 tested pregnant women from South Africa

From Kalafong Provincial Tertiary Hospital in Atteridgeville, Pretoria. Abstract only (click here). Citation: N. Mopane F. Molokoane M. Mojela L. Seopela L.C. Snyman. First results of universal SARS-CoV-2 virus testing of asymptomatic pregnant patients presenting for antenatal care at the Kalafong Provincial Tertiary Hospital. Obstetrics and Gynaecology Forum Vol. 30, No. 2 Jan 2020

Study 586 – Case report from France

From Service de Gynécologie-Obstétrique, Centre Fédératif de Pelvi-Périnéologie, CHU de Nantes, Nantes (click here or main (12)). Citation: Smati S, Mahot P, Bourdiol A, Ploteau S, Hadjadj S, Cariou B. Euglycaemic ketoacidosis during gestational diabetes with concomitant COVID-19 infection. Diabetes Metab. 2020 Jul 29:S1262-3636(20)30100-2. doi: 10.1016/j.diabet.2020.07.008. Epub ahead of print. PMID: 32738403; PMCID: PMC7387919.

Study 585 – Case report from India

From Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Sawangi, Wardha, Maharashtra (click here or 2838-Article Text-7183-1-10-20200818 (1)). Citation: Priyanka Singh, Neema Acharya, & Neha Verma. (2020). Experience of managing covid-19 suspected case in labour in a green zone district tertiary care hospital. International Journal of Research in Pharmaceutical Sciences, 11(SPL1), 500-505. https://doi.org/10.26452/ijrps.v11iSPL1.2838

Study 584 – case report from Iran

From Imam Ali Hospital, Alborz University of Medical Sciences, Karaj (click here or main (11)). Citation: Motlagh AJ, Esmaelzadeh Saeieh S, Parhigar O, Salehi L. An asthmatic pregnant woman with COVID-19: A case report study. Respir Med Case Rep. 2020;31:101296. doi: 10.1016/j.rmcr.2020.101296. Epub 2020 Nov 19. PMID: 33240787; PMCID: PMC7676370.

Study 583 – case report from Spain

From Hospital Universitario 12 de Octubre, Madrid (click here or main (10)). Citation: López Pérez V, Cora Vicente J, Echevarría Granados C, Salcedo Vázquez ML, Estol F, Tebar Cuesta MY. Postpartum consciousness disturbance: can covid-19 cause posterior reversible encephalopathy syndrome? Rev Esp Anestesiol Reanim. 2020 Nov;67(9):511-515. English, Spanish. doi: 10.1016/j.redar.2020.06.008. Epub 2020 Jul 14. PMID: 33036761; PMCID: PMC7359790.

Study 582 – Case report from India

From Dr. RML Hospital, New Delhi, which has not previously reported cases  (click here or fmaa094). Citation: Bandyopadhyay T, Sharma A, Kumari P, Maria A, Choudhary R. Possible Early Vertical Transmission of COVID-19 from an Infected Pregnant Female to Her Neonate: A Case Report. J Trop Pediatr. 2020 Nov 22:fmaa094. doi: 10.1093/tropej/fmaa094. Epub ahead of print. PMID: 33221859; PMCID: PMC7717437.

29th January – studies 574 to 581 added

Study 581 – Placental analysis of 39 cases from USA

From Yale New Haven Hospital so probably overlap with studies 132, 155 and 314 (click here or 2021.01.25.21250452v1.full). Citation: Alice Lu-Culligan, Arun R. Chavan, Pavithra Vijayakumar, Lina Irshaid, Edward M. Courchaine, Kristin M. Milano, Zhonghua Tang, Scott D. Pope, Eric Song, Chantal B.F. Vogels, William J. Lu-Culligan, Katherine H. Campbell, Arnau Casanovas-Massana, Santos Bermejo, Jessica M. Toothaker, Hannah J. Lee, Feimei Liu, Wade Schulz, John Fournier, M. Catherine Muenker, Adam J. Moore, Yale IMPACT Team, Liza Konnikova, Karla M. Neugebauer, Aaron Ring, Nathan D. Grubaugh, Albert I. Ko, Raffaella Morotti, Seth Guller, Harvey J. Kliman, Akiko Iwasaki, Shelli F. Farhadian. SARS-CoV-2 infection in pregnancy is associated with robust inflammatory response at the maternal-fetal interface. medRxiv 2021.01.25.21250452; doi: https://doi.org/10.1101/2021.01.25.21250452

Study 580 – 2,126 cases from Brazil

From the Brazilian Ministry of Health, “severe acute respiratory syndrome” tracking database (click here or 2021.01.22.21250346v1.full). For pregnancies see table 1. Likely overlap with studies 66, 138, 182, 194, 201, 213, 248, 249, 278, 309, 358, 426, 552, and 565. Citation: Eduardo Pietre, Gabriel P Amorim, Maria F F Bittencourt, Marcelo Ribeiro-Alves, Mariana Acquarone Prevalent comorbidities among young and underprivileged: Death portrait of COVID-19 among 235 555 hospitalized patients in Brazil. medRxiv 2021.01.22.21250346; doi: https://doi.org/10.1101/2021.01.22.21250346

Study 579 – 22 cases from USA

The authors are from Washington University in St. Louis, Missouri (click here or 1-s2.0-S2589933321000148-main). If the unnamed hospital was Barnes Jewish these cases may overlap with studies 69, 259 and 290. Citation: Megan C. OAKES MD , Annessa S. KERNBERG MD , Ebony B. CARTER MD MPH , Megan E. FOELLER MD , Arvind PALANISAMY MD FRCA , Nandini RAGHURAMAN MD MS , Jeannie C. KELLY MD MS , Pregnancy as a risk factor for severe coronavirus 2019 (COVID-19) disease using standardized clinical criteria, American Journal of Obstetrics & Gynecology MFM (2021), doi: https://doi.org/10.1016/j.ajogmf.2021.100319

Study 578 – serology of 88 cases from USA

From New York-Presbyterian Hospital, Weill Cornell, so probably overlapping with many previous studies (click here or 1-s2.0-S0002937821000533-main). Citation: Kubiak JM, Murphy EA, Yee J, Cagino K, Friedlander RL, Glynn SM, Matthews KC, Jurkiewicz M, Sukhu AC, Zhao Z, Prabhu M, Riley L, Yang YJ, SARS-CoV-2 serology levels in pregnant women and their neonates., American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.01.016.

Study 577 – Case report from Qatar

From Women’s Wellness and Research Center, Hamad Medical Corporation, Doha, which has not previously reported cases (click here or ccr3.3485). Probably included in studies 364 and 407. Citation: Yaqoub, S, Ahmad, S, Mansouri, Z, et al. Management of life‐threatening acute respiratory syndrome and severe pneumonia secondary to COVID‐19 in pregnancy: A case report and literature review. Clin Case Rep. 2021; 9: 137– 143. https://doi.org/10.1002/ccr3.3485

Study 576 – 9 ECMO cases from USA & Italy

From Houston, Iowa, New York, Boston and Bergamo (click here or Successful_Treatment_of_Pregnant_and_Postpartum.4). Citation: Barrantes JH, Ortoleva J, O’Neil ER, Suarez EE, Beth Larson S, Rali AS, Agerstrand C, Grazioli L, Chatterjee S, Anders M. Successful Treatment of Pregnant and Postpartum Women With Severe COVID-19 Associated Acute Respiratory Distress Syndrome With Extracorporeal Membrane Oxygenation. ASAIO J. 2021 Feb 1;67(2):132-136. doi: 10.1097/MAT.0000000000001357. PMID: 33229971.

Study 575 – 66 cases from Russia

Cared for at the National Medical Research Center for Obstetrics, Gynecology and Perinatology, Ministry of Healthcare of Russian Federation in Moscow which has not previously reported cases (click here or IJMF_0_1850683). Possible inclusion in study 278. Citation: Shmakov RG, Prikhodko A, Polushkina E, Shmakova E, Pyregov A, Bychenko V, Priputnevich TV, Dolgushin GO, Yarotskaya E, Pekarev O, Bolibok N, Degtyarev D, Sukhikh GT. Clinical course of novel COVID-19 infection in pregnant women. J Matern Fetal Neonatal Med. 2020 Nov 29:1-7. doi: 10.1080/14767058.2020.1850683. Epub ahead of print. PMID: 33249969; PMCID: PMC7711745.

Study 574 – Case report from Italy

From University Hospital, Modena, so probably included in studies 64, 117 and 252 (click here or R09Y9999N00A20113005). Citation: Sileo FG, Tramontano AL, Leone C, Meacci M, Gennari W, Ternelli G, La Marca A, Lugli L, Berardi A, Facchinetti F, Bertucci E. Pregnant woman infected by Coronavirus Disease (COVID-19) and calcifications of the fetal bowel and gallbladder: a case report. Minerva Ginecol. 2020 Nov 30. doi: 10.23736/S0026-4784.20.04717-6. Epub ahead of print. PMID: 33249821.

28th January – studies 570 to 573 added

Study 573 – 240 cases from USA

From 35 sites in Washington State (click here or 1-s2.0-S0002937821000338-main). These cases overlap with those in studies 83, 102, 139 and 389. Citation: Lokken EM, Huebner EM, Taylor GG, Hendrickson S, Vanderhoeven J,Kachikis A, Coler B, Walker CL, Sheng JS, al-Haddad BJS, McCartney SA, Kretzer NM, Resnick R,Barnhart N, Schulte V, Bergam B, Ma KK, Albright C, Larios V, Kelley L, Larios V, Emhoff S, Rah J,Retzlaff K, Thomas C, Paek BW, Hsu RJ, Erickson A, Chang A, Mitchell T, Hwang JK, Erickson S,Delaney S, Archabald K, Kline CR, LaCourse SM, Adams Waldorf KM, For the Washington StateCOVID-19 in Pregnancy Collaborative, Disease Severity, Pregnancy Outcomes and Maternal Deaths among Pregnant Patients with SARS-CoV-2 Infection in Washington State, American Journal ofObstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2020.12.1221.

Study 572 – Case report from Romania

From ‘Dr Carol Davila’ Central Military Emergency University Hospital, Bucharest, which has not previously reported cases (click here or etm_21_1_9524_PDF). Citation: Florea AA, Sirbu CA, Ghinescu MC, Plesa CF, Sirbu AM, Mitrica M and Ionita‑Radu F: SARS‑CoV‑2, multiple sclerosis, and focal deficit in a postpartum woman: A case report. Exp Ther Med 21: 92, 2021

Study 571 – serological testing in Spain

From Madrid (click here or pone.0243029). Overlap with study 458. Citation: Villalaı´n C, HerraizI, Luczkowiak J, Pe´rezRivilla A, Folgueira MD, Mejı´a I, et al. (2020) Seroprevalence analysis of SARS-CoV-2 in pregnant women along the first pandemic outbreak and perinatal outcome. PLoS ONE 15(11): e0243029. https://doi.org/10.1371/journal. pone.0243029

Study 570 – 1,120 cases from USA

Abstract reporting 1,129 pregnant cases from Los Angeles county (click here or 1-s2.0-S0027968420302765-main). Of those who have given birth no neonates tested positive. Citation: L. Khadijah Lang, Covid-19 Maternal-Neonate Vertical Transmission Rates in Los Angeles County, Journal of the National Medical Association, Volume 112, Issue 5, Supplement, 2020, Pages S36-S37, ISSN 0027-9684, https://doi.org/10.1016/j.jnma.2020.09.093. (http://www.sciencedirect.com/science/article/pii/S0027968420302765)

27th January – studies 567 to 569 added

Study 569 – 39 cases from Turkey

Cared for at Ankara City Hospital so probably overlap with studies 203, 223, 244, 399, 444 and 512 (click here or [16193997t). Citation: Erol Koç, E. M., Fındık, R. B., Akkaya, H., Karadağ, I., Tokalıoğlu, E. Ö., & Tekin, Ö. M. (2020). Comparison of hematological parameters and perinatal outcomes between COVID-19 pregnancies and healthy pregnancy cohort, Journal of Perinatal Medicine (published online ahead of print 2020), 000010151520200403. doi: https://doi.org/10.1515/jpm-2020-0403

Study 568 – Case report from USA

Conference poster from Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY which has not previously reported cases (click here or ). Citation: Wander Praneet, He Qiu, Ceena Chandrabos, David Bernstein, Sanjaya Satapathy. P2162 (S2415). – COVID-19 Infection Presenting as Acute Hepatitis in a 22-Week Pregnant Woman. American Journal of Gastroenterology. Conference: 2020 Annual Scientific Meeting of the American College of Gastroenterology, ACG 2020. 115 (SUPPL) (pp S1282), 2020. Date of Publication: October 2020. AN: 633658549

Study 567 – Case report from USA

Cared for at Loyola University Medical Center, Chicago, Illinois, which has not previously reported cases (click here or S2301_COVID_19_and_Ulcerative_Colitis_in_Pregnancy.2301). Citation: Lewine, Eliza MD1; Trieu, Judy MD, MPH2; Asamoah, Nikiya MD2; Venu, Mukund MD, FACG2; Naik, Amar MD2 S2301 COVID-19 and Ulcerative Colitis in Pregnancy, The American Journal of Gastroenterology: October 2020 – Volume 115 – Issue – p S1217 doi: 10.14309/01.ajg.0000711252.28660.fc

26th January – studies 550 to 566 added

Study 566 – Two cases from Bangladesh

One pregnant woman with Covid-19 survived. The other died (click here or JSAFOG-12-258). They were both cared for at Chittagong Medical College Hospital, Chattogram, which has not previously reported cases. Citation: Rashid F, Shahnaz S, Sharmin R, et al. Pregnancy with COVID-19: Weal and Woe. J South Asian Feder Obst Gynae 2020;12(4):258–260.

Study 565 – Case report from Brazil

Cared for at Fundação Hospital de Clínicas Gaspar Vianna, Belém, Pará state, which has not previously reported cases (click here or en_1678-4170-abc-115-05-0936). Citation: HOLANDA, Lucianna Serfaty de et al. Infecção por COVID-19 em Gestante Cardiopata. Arq. Bras. Cardiol. [online]. 2020, vol.115, n.5 [cited 2021-01-26], pp.936-938. Available from: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0066-782X2020001300936&lng=en&nrm=iso&gt;. Epub Dec 07, 2020. ISSN 1678-4170. http://dx.doi.org/10.36660/abc.20200517.

Study 564 – Case report from Iran

Cared for at Urmia University of Medical Sciences, Urmia, which has not previously reported cases (click here or archcid-15-5-104394). Citation: Zarrintan A, Boeoofeh B , Rabieipour M , Mohammadi A, Khademvatani K, et al. Pulmonary Thromboembolism in a Pregnant Patient with Severe COVID19: A Novel Case Report and Review of Literature, Arch Clin Infect Dis. 2020 ; 15(5):e104394. doi: 10.5812/archcid.104394.

Study 563 – Case report from USA

From School of Medicine and Public Health, University of Wisconsin, Madison, which has not previously reported cases (click here or 1-s2.0-S221491122030103X-main). Citation: Jennifer Jacobson, Kathleen Antony, Michael Beninati, William Alward, Kara K. Hoppe, Use of dexamethasone, remdesivir, convalescent plasma and prone positioning in the treatment of severe COVID-19 infection in pregnancy: A case report, Case Reports in Women’s Health, Volume 29, 2021, e00273, ISSN 2214-9112, https://doi.org/10.1016/j.crwh.2020.e00273. (http://www.sciencedirect.com/science/article/pii/S221491122030103X

Study 562 – Case report from India

From Lokmanya Tilak Muncipal General Hospital, Mumbai (click here or JSAFOG-12-243) so probably included in study 245. Citation: Mevada SA, Mehendale MA, Nayak AH, et al. Cardiomyopathy in Pregnancy with COVID-19: An Enigma. J South Asian Feder Obst Gynae 2020;12(4):243–244

Study 561- Case report from USA

A mother with Covid-19 gave birth to a baby with an ischaemic upper limb (click here or [21928959 – Case Reports in Perinatal Medicine] Neonate born with ischemic limb to a COVID-19 positive mother_ management and review of literature). The baby was cared for at Zucker School of Medicine at Hofstra, Northwell, New York. Citation: Perveen, S., Millington, K. A., Acharya, S., Grag, A., & Boyar, V. (2021). Neonate born with ischemic limb to a COVID-19 positive mother: management and review of literature, Case Reports in Perinatal Medicine, 10(1), 20200086. doi: https://doi.org/10.1515/crpm-2020-0086

Study 560 – 25 cases from France

Cared for at Cochin Hospital (Port-Royal Maternity) Paris (click here or 1-s2.0-S2468784720304177-main). Probably included in studies 150, 161 and 239. Citation: Tsatsaris V, Mariaggi AA, Launay O, Couffignal C, Rousseau J, Ancel PY, Marcault E, Ville Y, Cordier AG, Vivanti A, Carrara J, Luton D, Dommergues M, Borie C, Kayem G, Alessandrini V, Lecomte L, Meritet JF, Leruez-Ville M, Goffinet F, Dubois C, Picone O, Vauloup Fellous C. SARS-COV-2 IgG antibody response in pregnant women at delivery. J Gynecol Obstet Hum Reprod. 2020 Dec 10;50(7):102041. doi: 10.1016/j.jogoh.2020.102041. Epub ahead of print. PMID: 33310133.

Study 559 – 22 cases from China

Cared for at Tongji hospital, Wuhan (click here or 1-s2.0-S0924857920304805-main (1)). Previously reported many times. Citation: He Z, Fang Y, Zuo Q, Huang X, Lei Y, Ren X, Liu D. Vertical transmission and kidney damage in newborns whose mothers had coronavirus disease 2019 during pregnancy. Int J Antimicrob Agents. 2020 Dec 9:106260. doi: 10.1016/j.ijantimicag.2020.106260. Epub ahead of print. PMID: 33309765.

Study 558 – 19 cases from Uzbekistan

Abstract only (click here). Cared for in Kagan maternity hospital in Bukhara which has not previously reported cases. Citation: GULCHEKHRA A, IKHTIYAROVA, NIGORA K. DUSTOVA, MAVLYUDA A. KHASANOVA, GULRUKH S. SULEYMANOVA, SALIM S. DAVLATOV. Pathomorphological changes of the placenta in pregnant women infected with coronavirus covid-19 International Journal of Pharmaceutical Research ; 13(1):1935-1942, 2021.

Study 557 – case report from Kyrgyzstan

Cared for at City Maternity Hospital No. 2, 225 Moskva Street, Bishkek-720010, which has not previously reported cases (click here or 341-Article Text-592-1-10-20210107). Citation: Zhumabekova A, Tagaev T, Yethindra V, Zhumabaeva S, Ysabaeva D, Imankulova B. A case report of a pregnant woman with coronavirus disease 2019 (COVID-19) and her live-born infant. Biomedicine [Internet]. 2021Jan.1 [cited 2021Jan.26];40(4):551-3. Available from: https://biomedicineonline.org/index.php/home/article/view/341

Study 556 – case report from Iran

Cared for at Vasei Hospital, Sabzevar University of Medical Sciences, Sabzevar, which has not previously reported cases (click here or Tanaffos-19-152). Citation: Pourdowlat G, Mikaeilvand A, Eftekhariyazdi M, Nematshahi M, Ebrahimi M, Kazemzadeh A. Prone-Position Ventilation in a Pregnant Woman with Severe COVID-19 Infection Associated with Acute Respiratory Distress Syndrome. Tanaffos. 2020;19(2):152-155.

Study 555 – 56 cases from Iran

Cared for at Nekouei-Hedayati-Forqani Hospital in Qom which has not previously reported cases (click here or 32025-Article Text-134703-5-10-20210108 (2)). Citation: Mirzaie M, Shafie H, Heidarifar R, Yousefi MS, Yousefi MS. Relationship between ABO Blood Group Type and COVID-19 Outcome in Pregnant Women. J Cell Mol Anesth [Internet]. 2020Sep.23 [cited 2021Jan.26];5(4):282-3. Available from: https://journals.sbmu.ac.ir/jcma/article/view/32025

Study 554 – 4 cases from Saudi Arabia

Cared for at King Saud University Medical City, Riyadh which has not previously reported cases (click here or JEGH-10-3-214). Citation: Barry M, AlMohaya A, AlHijji A, Akkielah L, AlRajhi A, Almajid F, Alsharidi A, Al-Shahrani FS, Alotaibi NH, Alanazi A, Ghonem L, Alhetheel A, Alsubaie S, Memish ZA. Clinical Characteristics and Outcome of Hospitalized COVID-19 Patients in a MERS-CoV Endemic Area. J Epidemiol Glob Health. 2020 Sep;10(3):214-221. doi: 10.2991/jegh.k.200806.002. PMID: 32954712; PMCID: PMC7509106.

Study 553 – 29 cases from USA

Screened at University of Illinois at Chicago which has not previously reported cases (click here or 10-1055-s-0040-1721416). Citation: Buhimschi CS, Elam GL, Locher SR, Norris-Stojak D, Aldasoqi H, Stephenson MD, Buhimschi IA. Prevalence and Neighborhood Geomapping of COVID-19 in an Underserved Chicago Pregnant Population. AJP Rep. 2020 Oct;10(4):e413-e416. doi: 10.1055/s-0040-1721416. Epub 2020 Dec 3. PMID: 33294287; PMCID: PMC7714615.

Study 552 – Case report from Brazil

Cared for at Hospital Universitário da Universidade Federal do Maranhão, São Luis, MA. which has not previously reported cases (click here or 1806-9282-ramb-66-12-1621). Citation: PESSOA, Fabrício Silva et al. Probable vertical transmission identified within six hours of life. Rev. Assoc. Med. Bras. [online]. 2020, vol.66, n.12 [cited 2021-01-26], pp.1621-1624. Available from: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302020001201621&lng=en&nrm=iso&gt;. Epub Dec 16, 2020. ISSN 1806-9282. https://doi.org/10.1590/1806-9282.66.12.1621.

Study 551 – Case report from USA

A maternal death from Covid-19 treated at St. Joseph’s University Medical Center, Paterson, New Jersey, which has not previously reported cases (click here or amjcaserep-21-e926591). Citation: Patel P, Kulkarni S, Guerrero M, Persaud C, Zuberi J, Rebein B. Emergency Cesarean Section at 38 Weeks of Gestation with COVID-19 Pneumonia: A Case Report. Am J Case Rep. 2020 Dec 19;21:e926591. doi: 10.12659/AJCR.926591. PMID: 33339814; PMCID: PMC7755590.

Study 550 – 67 cases from USA

From Massachusetts General Hospital, Boston (click here or ofaa524). Overlap with studies 142, 231, 262, 519, 531. Citation: M D Soffer, L L Shook, K James, M R Sawyer, A Ciaranello, R Mahrouk, S N Bernstein, A A Boatin, A G Edlow, C York-Best, A J Kaimal, I T Goldfarb, Protocol-Driven Intensive Outpatient Management of Pregnant Patients With Symptomatic Coronavirus Disease 2019, Open Forum Infectious Diseases, Volume 7, Issue 11, November 2020, ofaa524, https://doi.org/10.1093/ofid/ofaa524

24th January – studies 547 to 549 added

Study 549 – 32 cases from UK

These 32 women with Covid-19 in pregnancy were cared for at Newham University Hospital in London which has not previously reported cases (click here or 1753495×20985403). One woman died. They are included in the UKOSS reports. Citation: Milln J, Heard S, Gunganah K, Velauthar L, Saeed F. Clinical characteristics and pregnancy outcomes of women diagnosed with SARS-CoV-2 in London’s most ethnically diverse borough: A cross-sectional study. Obstetric Medicine. January 2021. doi:10.1177/1753495X20985403

Study 548 – 279 cases from Spain

Of 279 women with SARS-Cov-2 cared for in the 42 hospitals of the Spanish Obstetric Emergency Group, 174 were asymptomatic, and are reported in this paper (click here or Cruz-Lemini viruses-13-00112). They likely overlap with many of the previous studies from Spain. Citation: Cruz-Lemini, M.; Ferriols Perez, E.; de la Cruz Conty, M.L.; Caño Aguilar, A.; Encinas Pardilla, M.B.; Prats Rodríguez, P.; Muner Hernando, M.; Forcen Acebal, L.; Pintado Recarte, P.; Medina Mallen, M.d.C.; et al. Obstetric Outcomes of SARS-CoV-2 Infection in Asymptomatic Pregnant Women. Viruses 2021, 13, 112. https://doi.org/10.3390/v13010112

Study 547 – 879 cases from India

This paper from Nair Hospital, Mumbai reports on five pregnant women with Covid-19 (out of 879 treated in that hospital) who also had heart disease (click here or Tilve India EJOG in press). They probably overlap with those in studies 225, 283 & 520, but the clinical details suggest no overlap with studies 369 & 501. Citation: Tilve A, Mahajan NN, Pandey A, Jnanananda B, Gadekar S, Mahale SD, Gajbhiye RK, Impact of COVID-19 on pregnant women with Rheumatic heart disease or Peripartum cardiomyopathy, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2021), doi:  https://doi.org/10.1016/j.ejogrb.2021.01.024

19 January – studies 545 and 546 added

Study 546 – 55,154 cases from the US

The CDC tracking data up to Jan 11th 2021 includes 55,154 pregnant women with Covid-19, of whom 66 (0.12%) had died (click here). Citation: Centres for Disease Control. Weekly COVID-19 Pregnancy Data updated January 11 2021, Accessed 19 Jan 2021. [important]

Study 545 – 3,928 cases from the Netherlands

January 6 update of NETHOSS registry includes 3,928 women with Covid-19 in pregnancy and further details (click here). 26 women were treated in ITU, 10 ventilated and one woman died. There is also a graph showing the first and second waves. Available here. Accessed 19 Jan 2021. [important]

18 January – study 544 added

Study 544 – 6,380 cases from US

Among these 6,380 women with Covid-19, 86 required ventilation and nine died (click here or jamainternal_jering_2021_ld_200094_1610581352.25094). They were identified from a multi-hospital database covering about 20% of the United States, so will overlap with other series. Citation: Jering KS, Claggett BL, Cunningham JW, et al. Clinical Characteristics and Outcomes of Hospitalized Women Giving Birth With and Without COVID-19. JAMA Intern Med. Published online January 15, 2021. doi:10.1001/jamainternmed.2020.9241

16 January – study 543 added

Study 543 – Case report from Ireland

A woman contracted COVID-19 at 36 weeks and was delivered by Caesarean (click here or 1-s2.0-S0143400421000205-main). Placental histology is described in detail. Mother and baby recovered. She was cared for at Cork University Maternity Hospital, which has not previously reported cases. Citation: Linehan L, O’Donoghue K, Dineen S, White J, Higgins JR, Fitzgerald B, SARS-CoV-2 Placentitis: An uncommon complication of maternal COVID-19, Placenta, https://doi.org/10.1016/j.placenta.2021.01.012.

14 January update – studies 540 to 542 added

Study 542 – 112 cases in ICU in UK

The 8 January ICNARC report includes 69 currently and 43 recently pregnant women in ICU with Covid-19 since 1 September 2020 (available here or ICNARC_COVID-19_Report_2021-01-08.pdf). 12 and 13 women respectively were ventilated. Citation: Intensive Care National Audit & Research Centre. ICNARC report on COVID-19 in critcal care: England, Wales and Northern Ireland 8 January 2021 Accessed 14 January 2021. https://www.icnarc.org/Our-Audit/Audits/Cmp/Reports&nbsp;

Study 541 – 73 cases from Spain

73 women with Covid-19 gave birth to 79 babies (click here or S1695403320305233). [Spanish. English abstract] No babies tested positive. From author affiliations they were probably cared for at Hospital General Universitario Gregorio Marañón, Madrid, so probably overlap with cases in studies 151 and 381. Citation: Gonzalo Solís-García, Ana Gutiérrez-Vélez, Isabel Pescador Chamorro, Elena Zamora-Flores, Sara Vigil-Vázquez, Elena Rodríguez-Corrales, Manuel Sánchez-Luna, Epidemiología, manejo y riesgo de transmisión de SARS-CoV-2 en una cohorte de hijos de madres afectas de COVID-19, Anales de Pediatría, 2020, ISSN 1695-4033, https://doi.org/10.1016/j.anpedi.2020.12.004. (http://www.sciencedirect.com/science/article/pii/S1695403320305233). Update 8 March For English language version (click here or SOlis Garcia Eng Ed An Pediatrica). English citation: Solís-García G, Gutiérrez-Vélez A, Pescador Chamorro I, Zamora-Flores E, Vigil-Vázquez S, Rodríguez-Corrales E, Sánchez-Luna M. Epidemiology, management and risk of SARS-CoV-2 transmission in a cohort of newborns born to mothers diagnosed with COVID-19 infection. An Pediatr (Engl Ed). 2021 Mar;94(3):173-178. doi: 10.1016/j.anpede.2020.12.006. Epub 2021 Jan 26. PMID: 33521167; PMCID: PMC7834971.

Study 540 – 9 cases from Israel

Of 1,326 asymptomatic pregnant women tested, 9 were positive for SARS-CoV-2 (click here or PIIS0002937821000259). No clinical details. From author affiliations they were probably cared for at Hadassah-Hebrew University Medical Center, Jerusalem, so may overlap with cases in study 330. Citation: Rottenstreich A, Zarbiv G, Kabiri D, Benenson S, Oster Y, Porat S, Sompolinsky Y, Reubinoff B, Rapid antigen detection testing for universal screening for SARS-CoV-2 in women admitted for delivery, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2021.01.002.

11 January update – studies 536 to 539 added

Study 539 -1,606 cases from UK and 2,398 from USA

This MedRxiv preprint describes 1,606 cases collected by the UK PanCovid registry and 2,398 from the US American Academy of Pediatrics Section on Neonatal Perinatal Medicine (AAP SONPM) National Perinatal COVID-19 Registry (click here or 2021.01.06.21249325v1.full). They likely overlap with other UK and US registries and reports. Citation: Edward Mullins, Mark Hudak, Jay Banerjee, Trace Getzlaff, Julia Townson, Kimberly Barnette, Rebecca Playle, Tom Bourne, Christoph Lees, PAN-COVID-investigators, National Perinatal COVID-19 Registry Study Group. Pregnancy and neonatal outcomes of COVID-19, co-reporting of common outcomes from the PAN-COVID and AAP SONPM registry. medRxiv 2021.01.06.21249325; doi: https://doi.org/10.1101/2021.01.06.21249325

23 Feb Update. Preprint in J Ultrasound Obstet Gynecol (click here or uog.23619). Cases reported from the AAP SONPM registry now 2,399. Two figures and four tables, referenced within, but missing from the MedRxiv preprint added. Citation: Mullins, E., Hudak, M.L., Banerjee, J., Getzlaff, T., Townson, J., Barnette, K., Playle, R., Bourne, T., Lees, C. on behalf of PAN‐COVID investigators and the National Perinatal COVID‐19 Registry Study Group (2021), Pregnancy and neonatal outcomes of COVID‐19: co‐reporting of common outcomes from PAN‐COVID and AAP SONPM registries. Ultrasound Obstet Gynecol. Accepted Author Manuscript. https://doi.org/10.1002/uog.23619

Study 538 – Case report from Iran

A woman who had recently delivered from a pregnancy complicated by pre-eclampsia contracted Covid-19 four days post-partum (click here or 1-s2.0-S2210778920301367-main). Despite intensive care and ventilation, she died on May 28th. She was cared for in Iranshahr University of Medical Sciences, Baluchestan, which has not previously reported cases. Citation: Fatemeh Azarkish, Firouzeh Sheikhi, Zohreh Mirkazehi, Saeed Kalkali, Paria Bameni Moghadam, Mahya Zahirniya, Preeclampsia and the crucial postpartum period for Covid-19 infected mothers: A case report, Pregnancy Hypertension, Volume 23, 2021, Pages 136-139, ISSN 2210-7789, https://doi.org/10.1016/j.preghy.2020.10.012. (http://www.sciencedirect.com/science/article/pii/S2210778920301367)

Study 537 – Case report of ECMO from USA

A woman with Covid-19 at 23 weeks gestation was treated with ECMO, and recovered (click here or mark ECMO pzaa189). From author affiliations she was likely treated at the University of Iowa Heart and Vascular Center, which has not previously reported pregnancy cases. However she may be included in study 535. Citation: Alex Mark, Jennifer P Crumley, Kristina L Rudolph, Kevin Doerschug, Anna Krupp, Maintaining Mobility in a Patient Who Is Pregnant and Has COVID-19 Requiring Extracorporeal Membrane Oxygenation: A Case Report, Physical Therapy, , pzaa189, https://doi.org/10.1093/ptj/pzaa189

Study 536 – 534 cases from Italy

This report, in Italian, includes 534 cases of Covid-19 in pregnancy, reported to the ITOSS registry between February 25th and July 10th 2020 (click here or itOSS 081-087_ART-Corsi (002)). There will be overlap with study 246. Citation: Edoardo Corsi, Alice Maraschini, Enrica Perrone, Michele Antonio Salvatore, Paola D’Aloja, Serena Donati, Gruppo di lavoro ItOSS COVID-194.  La preparedness dell’Italian obstetric surveillance system in occasione della pandemia da SARS-CoV-2: aspetti metodologici di uno studio di popolazione. (The preparedness of the Italian obstetric surveillance system in the response to the emergency of the SARS-CoV-2 pandemic: methodological aspects of a population-based study) Epidemiol Prev 2020; 44 (5-6) Suppl 2:81-87. doi: 10.19191/EP20.5-6.S2.089

8 January update – study 535 added

Study 535 – 22 pregnant women treated with ECMO

This series of people with Covid-19 treated with ECMO between Jan 16 and May 1, 2020, from 213 hospitals in 36 countries, includes 22 pregnant women (click here or PIIS0140673620320080). No separate outcome data. Citation: Barbaro, Ryan P, Alexander, Peta et al. Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry The Lancet, Volume 396, Issue 10257, 1071 – 1078.

7 January update – study 534 added

Study 534 – 145 cases from Italy

Of 145 pregnant women with SARS-CoV-2  infection, 116 were symptomatic (click here or DiGuardo2021_Article_PoorMaternalNeonatalOutcomesIn). Seven mothers and nine neonates died. They were cared for in two unnamed tertiary referral hospitals between March and July 2020. The authors are affiliated with one hospital in Calabria, in the south, two in Catania, Sicily and one in Vicenza in the North East. Ethics approval was from another hospital in Sicily. Assuming the two hospitals are in Sicily, these cases have probably not been reported. None of the author affiliations were with Palermo, study 355. Citation: Di Guardo F, Di Grazia FM, Di Gregorio LM, Zambrotta E, Carrara G, Gulino FA, Tuscano A, Palumbo M. Poor maternal-neonatal outcomes in pregnant patients with confirmed SARS-Cov-2 infection: analysis of 145 cases. Arch Gynecol Obstet. 2021 Jan 3:1–6. doi: 10.1007/s00404-020-05909-4. Epub ahead of print. PMID: 33389111; PMCID: PMC7778712.

6 January update – study 533 added

Study 533 – 1,148 cases from UK

This Medxiv preprint describes 1,148 pregnant women with SARS-CoV-2, 722 with symptoms. who were admitted to hospital (click here or UKOSS Preprint (002)).  Of 640 completed pregnancies, there were 16 pregnancy losses before 24 weeks, 5 stillbirths and 2 neonatal deaths. Eight mothers died. Collected from all 194 consultant-led obstetric units in the United Kingdom between 1st March and 31st August 2020, they therefore overlap with those reported in study 92. Citation: Nicola Vousden, Kathryn Bunch, Edward Morris, Nigel Simpson, Christopher Gale, Patrick O’Brien, Maria Quigley, Peter Brocklehurst, Jennifer J Kurinczuk, Marian Knight. The incidence, characteristics and outcomes of pregnant women hospitalized with symptomatic and asymptomatic SARS-CoV-2 infection in the UK from March to September 2020: a national cohort study using the UK Obstetric Surveillance System (UKOSS). medRxiv 2021.01.04.21249195; doi: https://doi.org/10.1101/2021.01.04.21249195 [important] Update 16 May. Peer review published (click here or study) Citation: Vousden N, Bunch K, Morris E, Simpson N, Gale C, O’Brien P, et al. (2021) The incidence, characteristics and outcomes of pregnant women hospitalized with symptomatic and asymptomatic SARS-CoV-2 infection in the UK from March to September 2020: A national cohort study using the UK Obstetric Surveillance System (UKOSS). PLoS ONE 16(5): e0251123. https://doi.org/10.1371/journal.pone.0251123

3 January update – studies 529 to 532 added

Study 532 – zero pregnancy cases in a city in Japan

All 1475 pregnant women and 1343 partners tested for COVID-19 by PCR in saliva in all 12 maternity facilities in Himeji city between May 29 and September 5, 2020 were negative (click here or jog.14591). Over the same period 74 non-pregnant patients had Covid-19 in the same city. Citation: Okamura S, Akamatsu N, Kitajima T, Nakabayashi K, Fukumoto S, Katayama T, Mizutani Y, Kiyomoto H, Yamada H. Screening of COVID-19 polymerase chain reaction tests using saliva for pregnant women and their partners in Himeji city. J Obstet Gynaecol Res. 2020 Dec 22. doi: 10.1111/jog.14591. Epub ahead of print. PMID: 33354868.

Study 531 – 68 cases from USA

This preprint includes 68 pregnant women with suspected or confirmed COVID-19 (click here or 2907ed6a-c4cd-4147-b0bd-a5c41c5afec6). They were recruited through social media. Authors are mostly affilated with Harvard Medical School or Massachusetts General Hospital. Citation: Mayopoulos G, Ein-Dor T, Li K, Chan S, Dekel S. Giving birth under hospital visitor restrictions: Heightened acute stress in childbirth in COVID-19 positive women. Res Sq [Preprint]. 2020 Dec 9:rs.3.rs-112882. doi: 10.21203/rs.3.rs-112882/v1. PMID: 33330856; PMCID: PMC7743075.

Study 530 – 70 cases from Iran

Of 70 pregnant women with COVID-19 hospitalized from early March to late April 2020, two mothers died (click here or aim-23-856). 15/32 births were premature but no other baby outcomes are reported. The patients were cared for in various unnamed hospitals in Guilan province. Author affiliations suggest that these included Al-Zahra Hospital, in Rasht, which has not previously reported cases. Shared authors suggest the maternal deaths may overlap with those reported in study 67. Citation: Kazemi Aski S, Sharami SH, Hosseinzadeh F, Hesni E, Dalil Heirati SF, Ghalandari M, Mousavi A. Risk Factors, Clinical Symptoms, Laboratory Findings and Imaging of Pregnant Women Infected with COVID-19 in North of Iran. Arch Iran Med. 2020 Dec 1;23(12):856-863. doi: 10.34172/aim.2020.114. PMID: 33356344.

Study 529 – Case report from the Netherlands

A woman with Covid-19 was delivered by Caesarean at 31 weeks (click here or piaa153). There was evidence of SARS-CoV-2 in the placenta and the baby developed complications of both prematurity and birth asphyxia. However the baby tested negative. They were cared for in Erasmus University Medical Center, Rotterdam, which has not previously reported cases. The case was probably included in the NETHOSS registry. Citation: Schoenmakers S, Snijder P, Verdijk RM, Kuiken T, Kamphuis SSM, Koopman LP, Krasemann TB, Rousian M, Broekhuizen M, Steegers EAP, Koopmans MPG, Fraaij PLA, Reiss IKM. Severe Acute Respiratory Syndrome Coronavirus 2 Placental Infection and Inflammation Leading to Fetal Distress and Neonatal Multi-Organ Failure in an Asymptomatic Woman. J Pediatric Infect Dis Soc. 2020 Dec 26:piaa153. doi: 10.1093/jpids/piaa153. Epub ahead of print. PMID: 33367801.

2 January update – studies 525-528 added

Study 528 – 16 cases from Singapore

16 pregnant women with COVID-19 cared for in 4 hospitals (abstract only click here). Citation: Mattar CN, Kalimuddin S, Sadarangani SP, Tagore S, Thain S, Thoon KC, Hong EY, Kanneganti A, Ku CW, Chan GM, Lee KZ, Yap JJ, Tan SS, Yan B, Young BE, Lye DC, Anderson DE, Yang L, Su LL, Somani J, Tan LK, Choolani MA, Chan JK. Pregnancy Outcomes in COVID-19: A Prospective Cohort Study in Singapore. Ann Acad Med Singap. 2020 Nov;49(11):857-869. PMID: 33381779.

Study 527 – 114 cases from Peru

114 pregnant women positive for SARS-CoV-2, between April 15 and May 10, 2020, who delivered in the National Perinatal Maternal Institute, Lima, which has not previously reported cases (English abstractonly click here). Three newborns died. Citation: Dávila-Aliaga C, Espínola-Sánchez M, Mendoza-Ibáñez E, Guevara-Ríos E, Torres-Marcos E, Hinojosa-Pérez R, Espinoza-Vivas Y, Álvarez-Carrasco R, Velásquez-Vásquez C, Meza-Santibáñez L, Gonzales-Carrillo O, Arango-Ochante P, Racchumí-Vela A, Saldaña-Díaz C. Resultados perinatales y serológicos en neonatos de gestantes seropositivas para SARS-CoV-2: estudio transversal descriptivo [Perinatal outcomes and serological results in neonates of pregnant women seropositive to SARS-CoV-2: A cross-sectional descriptive study]. Medwave. 2020 Dec 21;20(11):e8084. Spanish. doi: 10.5867/medwave.2020.11.8084. PMID: 33382393.

Study 526 – 35 pregnant women from Switzerland

There were 35 pregnant women in this preprint hospital registry study up to August 31st, 2020 (click here or 2020.12.10.20246884v2.full). One went to ICU. No mothers died. No baby outcomes were reported. They were cared for 20 hospitals listed in the paper, and may overlap with cases in studies 72, 310 & 427. Citation: Amaury Thiabaud, Anne Iten, Carlo Balmelli, Laurence Senn, Nicolas Troillet, Andreas Widmer, Domenica Flury, Peter W. Schreiber, Miriam Vázquez, Lauro Damonti, Michael Buettcher, Danielle Vuichard-Gysin, Christoph Kuhm, Alexia Cusini, Thomas Riedel, Yvonne Nussbaumer, Roman Gaudenz, Ulrich Heininger, Christoph Berger, Franziska Zucol, Sara Bernhard-Stirnemann, Natascia Corti, Petra Zimmermann, Anita Uka, Anita Niederer-Loher, Céline Gardiol, Maroussia Roelens, Olivia Keiser. SARS-CoV-2/COVID-19 hospitalised patients in Switzerland: a prospective cohort profile. medRxiv 2020.12.10.20246884; doi: https://doi.org/10.1101/2020.12.10.20246884

Study 525 – 41 cases from Canada

Of 41 pregnant women testing positive for SARS-CoV-2, 30 had symptoms (click here or montreal). Two women required ventilation. There were no maternal deaths. No baby outcomes were reported. They were cared for in the Jewish General Hospital in Montreal, Quebec, which has not previously reported cases. Citation: Trahan, Marie-Julie et al.Screening and Testing Pregnant Patients for SARS-CoV-2: First-Wave Experience of a Designated COVID-19 Hospitalization Centre in Montreal J Obstet Gynaecol Can 2020;36(00):1−5. https://doi.org/10.1016/j.jogc.2020.11.001

1 January – study 254 added

Study 524 – 30 cases from Spain

13 pregnant and 17 postpartum women with Covid-19 in this series collected between 15th March and 15th October (click here or 2020.12.10.20246959v2.full). The authors suggest that pregnancy infection was more common in the second wave. Citation: Simona Iftimie, Ana F. López-Azcona, Immaculada Vallverdú, Salvador Hernàndez-Flix, Gabriel de Febrer, Sandra Parra, Anna Hernández-Aguilera, Francesc Riu, Jorge Joven, Jordi Camps, Antoni Castro, REUSCOVID Study Group. First and second waves of coronavirus disease-19: A comparative study in hospitalized patients in Reus, Spain. medRxiv 2020.12.10.20246959; doi: https://doi.org/10.1101/2020.12.10.20246959

31 December – study 523 added

Study 523 – seropositivity in pregnancy in Sweden

This preprint reports that about 15% of randomly sampled asymptomatic pregnant women from the Stockholm area had antibodies to SARS-CoV-2 by December 2020 (click here or 2020.12.24.20248821v1.full). 96% at levels that would be expected to confer immunity. Citation: Xaquin Castro Dopico, Sandra Muschiol, Murray Christian, Leo Hanke, Daniel J. Sheward, Nastasiya F. Grinberg, Gordana Bogdanovic, Gerald M. Mcinerney, Tobias Allander, Chris Wallace, Ben Murrell, Jan Albert, Gunilla B. Karlsson Hedestam. Seropositivity in blood donors and pregnant women during 9-months of SARS-CoV-2 transmission in Stockholm, Sweden. medRxiv 2020.12.24.20248821; doi: https://doi.org/10.1101/2020.12.24.20248821

29 December – studies 521 & 522 added.  Citation for study 313 updated.

Study 522 – Pancreatitis in a pregnant woman with Covid-19

A woman with severe Covid-19 at 33 weeks gestation also developed pancreatitis (click here or Acute_Pancreatitis_in_a_Pregnant_Patient_With.75). She went into preterm labour and delivered vaginally. Both mother and baby recovered. From author affiliations she was cared for at the Mayo Clinic, Rochester, Minnesota. USA, which has not previously reported cases. Citation: Narang K, Szymanski LM, Kane SV, Rose CH. Acute Pancreatitis in a Pregnant Patient With Coronavirus Disease 2019 (COVID-19). Obstet Gynecol. 2020 Dec 22;Publish Ahead of Print. doi: 10.1097/AOG.0000000000004287. Epub ahead of print. PMID: 33355431.

Study 521 – 57 cases from India

Between May 5, and June 5, 2020, 348 pregnant women were tested and 57 positive for SARS-CoV-2 at Safdarjung Hospital, New Delhi (click here or PIIS170121632030829X). Three women died. Five babies tested positive but survived. Two test negative babies died. Likely overlap with study 441. Citation: Sumitra Bachani, Renu Arora, Anjali Dabral, Sheeba Marwah, Pratima Anand, K. Sravani Reddy, Nitesh Gupta, Balwinder Singh, Clinical Profile, Viral Load, MaternalFetal Outcomes of Pregnancy With COVID-19: 4-Week Retrospective, Tertiary Care Single-Centre Descriptive Study J Obstet Gynaecol Can 2020;000(000):1−9. https://doi.org/10.1016/j.jogc.2020.09.021

24 December – study 520 added

Study 520 – 879 cases from India

This series from Nair Hospital, Mumbai included 879 women with Covid-19 seen between April 4 and  September 10, 2020 (click here or ijgo.13508). They likely overlap with cases reported in studies 225, 283, 369 and 501. Citation: Mahajan, N.N., Ansari, M., Gaikwad, C., Jadhav, P., Tirkey, D., Pophalkar, M.P., Bhurke, A.V., Modi, D.N., Mahale, S.D. and Gajbhiye, R.K. (2020), Impact of SARS‐CoV‐2 on multiple gestation pregnancy. Int J Gynecol Obstet. https://doi.org/10.1002/ijgo.13508

23 December – studies 518 and 519 added

Study 519 – 127 cases from USA

A detailed analysis of viraemia, and placental transfer of virus and antibodies, in 127 pregnant women with SARS-CoV-2 (click here or edlow_2020_oi_200960_1607964328.94511). They were cared for in Massachusetts General, Brigham and Women’s Hospital, and Beth Israel Deaconess Medical Center, in Boston, Massachusetts between April 2 & June 13, 2020, and likely overlap with those in studies 129, 142, 231 and 232. Citation: Edlow AG, Li JZ, Collier AY, et al. Assessment of Maternal and Neonatal SARS-CoV-2 Viral Load, Transplacental Antibody Transfer, and Placental Pathology in Pregnancies During the COVID-19 Pandemic. JAMA Netw Open. 2020;3(12):e2030455. doi:10.1001/jamanetworkopen.2020.30455

Study 518 – 7,028 cases from Mexico

7,028 pregnant with COVID-19  identified through the Mexican Public Health Network between February 1st and October 27th (click here or Martinez Portilla AJOG). 93 (1.3%) women died. They had been cared for 475 unnamed monitoring hospitals. A further analysis of the series reported in study 513, with additional cases. Citation: Martinez Portilla RJ, Smith ER, He S, Torres JT, Espino-Y-Sosa S, Solis-Paredes JM, Poon LC, Young pregnant women are also at an increased risk of mortality and severe illness due to COVID-19: Analysis of the Mexican National Surveillance Program, American Journal of Obstetrics and Gynecology (2021), doi: https://doi.org/10.1016/j.ajog.2020.12.1197. [important]

22 December – study 517 added

Study 517 – 47 screen positives in US

Of 126 women screened on admission in labour to Elmhurst Hospital, between March 29 and April 22, 45 tested positive for SARS-CoV-2 (click here or pone.0238409). They likely overlap with those in studies 160 and 236. Citation: Maru S, Patil U, Carroll-Bennett R, Baum A, Bohn-Hemmerdinger T, Ditchik A, et al. (2020) Universal screening for SARS-CoV-2 infection among pregnant women at Elmhurst Hospital Center, Queens, New York. PLoS ONE 15(12): e0238409. https://doi.org/10.1371/journal. pone.0238409

19 December – studies 513 to 516 added

Study 516 – 22 cases from China

22 neonates born to women with Covid-19 and admitted to Tongji Hospital, Wuhan, from January 1 to April 1, 2020 (click here or 1-s2.0-S0924857920304805-main). These cases have likely been reported before. Citation: Zheng He, Yinian Fang, Qin Zuo, Xiaoxing Huang, Yongfang Lei, Xiuhua Ren, Dong Liu, Vertical transmission and kidney damage in newborns from coronavirus disease 2019 infection pregnant mother, International Journal of Antimicrobial Agents (2020), doi: https://doi.org/10.1016/j.ijantimicag.2020.106260

Study 515 – 90 cases from Iran

45 symptomatic and 45 asymptomatic women with SARS-CoV-2 were compared (click here or Pregnancy outcomes among symptomatic and asymptomatic women infected with COVID 19 in the west of Iran a case control study). They were cared for in various hospitals of Hamadan Province from 1 September 2020 to 15 November 2020, and therefore should not overlap with study 375Citation: Ensiyeh Jenabi , Saeid Bashirian , Salman Khazaei , Seyedeh Zahra Masoumi , Samereh Ghelichkhani , Firoozeh Goodarzi & Mohammad Mirzaei (2020): Pregnancy outcomes among symptomatic and asymptomatic women infected with COVID-19 in the west of Iran: a case-control study, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1861599

Study 514 – 9 cases from Iran

A woman with Covid-19 gave birth at 37 weeks (click here or aaem-9-e5). The baby tested positive. The babies of 8 other affected women in the same hospital tested negative. They were cared for at Mahdiyeh Hospital, Shahid Beheshti University of Medical Sciences, Tehran, which has not previously reported cases. Citation: Parsa Y, Shokri N, Jahedbozorgan T, Naeiji Z, Zadehmodares S, Moridi A. Possible Vertical Transmission of COVID-19 to the Newborn; a Case Report: Vertical Transmission and The Coronavirus . Arch Acad Emerg Med [Internet]. 2020Nov.15 [cited 2020Dec.19];9(1):e5. Available from: https://journals.sbmu.ac.ir/aaem/index.php/AAEM/article/view/923

Study 513 – 5,183 cases in Mexico

5,183 pregnant women with Covid-19 identified throught the National Data Registry of Mexico from February 1st, to October 28th, 2020 (click here or uog.23575). 77 (1·5%) mothers died. They had been cared for in 475 unnamed monitoring hospitals, located in all 32 states. Citation: Martinez‐Portilla, R.J., Sotiriadis, A., Chatzakis, C., Torres‐Torres, J., Espino y Sosa, S., Sandoval‐Mandujano, K., Castro‐Bernabe, D.A., Medina‐Jimenez, V., Monarrez‐Martin, J.C., Figueras, F. and Poon, L.C. (2020), Pregnant women with SARS‐CoV‐2 infection are at higher risk of death and severe pneumonia: propensity score‐matched analysis of a nationwide prospective cohort study (COV19Mx). Ultrasound Obstet Gynecol. Accepted Author Manuscript. https://doi.org/10.1002/uog.23575

18 December – studies 511 (belatedly) and 512 added

Study 512 – 60 cases from Turkey

60 pregnant women with Covid-19 (click here or jmv.26725). Cared for in Ankara City Hospital between 26 June and 27 August 2020.  Probably overlapping with studies 31, 203, 223, 244, 399 & 444. Citation: Erol, S.A., Tanacan, A., Anuk, A.T., Tokalioglu, E.O., Biriken, D., Keskin, H.L., Tekin, O.M., Yazihan, N. and Sahin, D. (2020), Evaluation of Maternal Serum Afamin and Vitamin E Levels in Pregnant Women with COVID‐19 and Its Association with Composite Adverse Perinatal Outcomes. J Med Virol. Accepted Author Manuscript. https://doi.org/10.1002/jmv.26725

Study 511 – 9 cases from China

We were originally unable to source this early paper despite it being cited in a number of early reports (click here or 1007-9408-23-0004s). Patients were treated in the People’s Hospital of Wuhan University from January 22 to February 1, 2020, and therefore likely reported many times elsewhere. In Chinese. Citation: Lei Di, Wang Chen, Li Chunyan, et al. Clinical analysis of 9 cases of pregnancy with new coronavirus pneumonia[J]. Chinese Journal of Perinatal Medicine, 2020,23 (03): 225-231. DOI: 10.3760/cma. j.cn113903-20200216-00117

17 December – study 510 added

Study 510 – 1,584 cases in Canada

The first report of the Canadian Covid in pregnancy registry CanCovid (click here or CANCOVID-Preg-report-1-BC-AB-ON-data_02DEC2020).  As of November 23rd, 2020, 1,584 pregnant women with SARS-CoV-2 had been reported in Canada. 430 are reported here in detail. Eight were admitted to ITU. Nos. of events which affected <6 woman are not reported. Citation: Deborah Money. CANADIAN SURVEILLANCE OF COVID-19 IN PREGNANCY: EPIDEMIOLOGY, MATERNAL AND INFANT OUTCOMES Report #1: Released December 2nd, 2020 School of Population & Public Health, University of British Colombia [important]

15 December update – study 509 added

Study 509 – Case in China

A woman with Covid-19 at 36 weeks was delivered by Caesarean on 24 January (click here or PIIS0007091220301318). She was cared for at Wuhan Red Cross Hospital grid.507948.7, which has not previously reported cases. Citation: Xia H, Zhao S, Wu Z, Luo H, Zhou C, Chen X. Emergency Caesarean delivery in a patient with confirmed COVID-19 under spinal anaesthesia. Br J Anaesth. 2020 May;124(5):e216-e218. doi: 10.1016/j.bja.2020.02.016. Epub 2020 Mar 17. PMID: 32192711; PMCID: PMC7118662.

14 December update – studies 501 (HT Rahul Gajbhiye) to 508 added

Study 508 – Case in Iran

A woman with Covid-19 was delivered by Caesarean section at term and suffered a post-partum pulmonary embolus (click here or 20-1383). She was cared for [undated] at Shiraz University of Medical Sciences, Iran, which has not previously reported cases. Citation: Khodamoradi Z, Boogar SS, Shirazi FKH, Kouhi P. COVID-19 and Acute Pulmonary Embolism in Postpartum Patient. Emerg Infect Dis. 2020;26(8):1937-1939. doi:10.3201/eid2608.201383

Study 507 – 71 cases in USA

71 pregnant women with Covid-19 and their babies (click here or s-0040-1713416) were cared for [March 31, to May 5, 2020] in Morristown Medical Center, and at Overlook Medical Center, New Jersey, and therefore may overlap with those reported in study 159. Citation: Griffin I, Benarba F, Peters C, Oyelese Y, Murphy T, Contreras D, Gagliardo C, Nwaobasi-Iwuh E, DiPentima MC, Schenkman A. The Impact of COVID-19 Infection on Labor and Delivery, Newborn Nursery, and Neonatal Intensive Care Unit: Prospective Observational Data from a Single Hospital System. Am J Perinatol. 2020 Aug;37(10):1022-1030. doi: 10.1055/s-0040-1713416. Epub 2020 Jun 13. PMID: 32534458; PMCID: PMC7416206.

Study 506 – 37 cases in USA

37 pregnant women with Covid-19 were cared for at Flushing Hospital Medical Centre or Jamaica Hospital Medical Centre, New York, between March 20, and April 30, 2020 (click here or IDOG2020-8460672). Neither hospital has previously reported cases. Citation: Sindy C. Moreno, Justin To, Hajoon Chun, Ivan M. Ngai, “Vertical Transmission of COVID-19 to the Neonate”, Infectious Diseases in Obstetrics and Gynecology, vol. 2020, Article ID 8460672, 5 pages, 2020. https://doi.org/10.1155/2020/8460672

Study 505 – Case in USA

A woman with clinical Covid-19 (PCR negative but antibody positive) at 26 weeks gestation required 23 days ventilation (click here or CRIOG2020-8891787). She delivered vaginally at 39 weeks. The baby was healthy. From author affiliations she was cared for at Presbyterian-Brooklyn Methodist Hospital, New York, so may be included in study 230 and possibly other studies from the NY Presbyterian network. Citation: Farah Alsayyed, Victoria Hastings, Sanford Lederman, “Expectant Management of a Critically Ill Pregnant Patient with COVID-19 with Good Maternal and Neonatal Outcomes”, Case Reports in Obstetrics and Gynecology, vol. 2020, Article ID 8891787, 6 pages, 2020. https://doi.org/10.1155/2020/8891787

Study 504 – 4 mothers, 5 babies in Italy

Four women with Covid-19 had five babies who became infected (click here or olivini It J Ped 2020). From author affiliations the babies were cared for at Bambino Gesù Children’s Hospital, Rome. The paper has no OB authors so it is not clear which maternity hospital cared for the mothers. However, it is possible that some of them were included in studies 76, 78 and 464. Citation: Olivini, N., Calò Carducci, F.I., Santilli, V. et al. A neonatal cluster of novel coronavirus disease 2019: clinical management and considerations. Ital J Pediatr 46, 180 (2020). https://doi.org/10.1186/s13052-020-00947-9

Study 503 – “Rooming in” in Italy

Of 61 mothers with Covid-19, and 62 neonates “roomed in”, only one baby got infected (click here or jamapediatrics_ronchi_2020_oi_200078_1605627156.62602). They were cared for in at 6
COVID-19 maternity centers, located in Lombardy, Northern Italy, between March 19 & May 2, 2020, and therefore probably overlap with those reported in the other Lombardy series. Citation: Ronchi A, Pietrasanta C, Zavattoni M, et al. Evaluation of Rooming-in Practice for Neonates Born to Mothers With Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Italy. JAMA Pediatr. Published online December 07, 2020. doi:10.1001/jamapediatrics.2020.5086

Study 502 – ICNARC 2nd wave, UK

The UK Intensive Care National Audit & Research Centre (ICNARC) is now reporting patients with Covid on ICU separately for the periods before and after 1 September 2020 (click here or ICNARC_COVID-19_Report_2020-12-11), For the period after 1 September, 13 currently pregnant and 12 recently pregnant women with Covid-19, had been admitted to ITU, of whom 8 and 10 respectively had been ventilated.

Study 501 – Case in India

A woman contracted Covid-19 at 30 weeks and developed delirium (click here or 1-s2.0-S1876201820306262-main). She recovered but the baby died. Three cases of post partum psychosis in women with Covid from the same hospital are mentioned. The hospital is Nair Hospital, Mumbai, so these cases may be included in studies 225, 283 & 369. Citation: Mahajan NN, Gajbhiye RK, Pednekar RR, Pophalkar MP, Kesarwani SN, Bhurke AV, Mahale SD, Delirium in a pregnant woman with SARS-CoV-2 infection in India, Asian Journal of Psychiatry (2020), doi: https://doi.org/10.1016/j.ajp.2020.10251

13 December update – studies 499 and 500 added

Study 500 – 7 cases in China

Seven pregnant women with Covid-19 (click here or 12098_2020_Article_3372). They were cared for in 5 provincial hospitals inHubei, namely Renmin Hospital of Wuhan University (n = 2) grid.412632.0, Huangshi Maternal and Child Health Hospital (n = 2) does not disambiguate, Jingzhou Maternal and Child Health Hospital (n = 1) grid.507996.4, Jingmen First Renmin Hospital (n = 1) does not disambiguate, and Zaoyang First Renmin Hospital (n = 1) which does not disambiguate. It is likely that the various Renmin hospital cases have been reported elsewhere. The Jingzhou case may not have been reported before. Citation: Nawsherwan, Khan S, Nabi G, Fan C, Wang S. Impact of COVID-19 Pneumonia on Neonatal Birth Outcomes. Indian J Pediatr. 2020;87(8):645-646. doi:10.1007/s12098-020-03372-2

Study 499 – 19 cases in China

17 mothers with Covid-19 and their babies (click here or 11684_2020_Article_772). They were cared for in Tongji Hospital in Wuhan, and therefore likely included in many previous reports. Citation: Liu W, Wang J, Li W, Zhou Z, Liu S, Rong Z. Clinical characteristics of 19 neonates born to mothers with COVID-19. Front Med. 2020;14(2):193-198. doi:10.1007/s11684-020-0772-y

12 December update – studies 493 to 498 added

Study 498 – Case in China

A 30-year-old woman with Covid-19 at 35-weeks was delivered by caesarean and became depressed and anxious after her baby was isolated (click here or JZUSB21-0394). From author affiliations she was cared for at the First Affiliated Hospital, Zhejiang University School of Medicine, grid.452661.2, Hangzhou, and may therefore the same case as in studies 4 and 9. Citation: Huang JW, Zhou XY, Lu SJ, et al. Dialectical behavior therapy-based psychological intervention for woman in late pregnancy and early postpartum suffering from COVID-19: a case report. J Zhejiang Univ Sci B. 2020;21(5):394-399. doi:10.1631/jzus.B2010012

Study 497 – Case in China

A woman contracted Covid-19 at 36 weeks (click here or 540_2020_Article_2796). She delivered by Caesarean at 37 weeks. Both mother and baby recovered. From author affiliatons she was cared for at the Second Affiliated Hospital of Xi’an Jiaotong University, grid.452672.0 Xi’an, Shaanxi, which has not previously reported cases. Citation: Du Y, Wang L, Wu G, Lei X, Li W, Lv J. Anesthesia and protection in an emergency cesarean section for pregnant woman infected with a novel coronavirus: case report and literature review. J Anesth. 2020;34(4):613-618. doi:10.1007/s00540-020-02796-6

Study 496 – Case in USA

A woman contracted Covid-19 and vulvovaginitis at 31 weeks (click here or s-0040-1713665). From author affiliations she was treated at the Hospital of the University of Pennsylvania, Philadelphia, so might be included in studies 86, 175, 302 & 350. Citation: Rubin ES, Sansone SA, Hirshberg A, Clement EG, Srinivas SK. Detection of COVID-19 in a Vulvar Lesion. Am J Perinatol. 2020 Sep;37(11):1183-1184. doi: 10.1055/s-0040-1713665. Epub 2020 Jul 2. PMID: 32615620; PMCID: PMC7516389.

Study 495 – 17 self-reported cases in Belgium

17 out of 6,470 self-selected pregnant or breast feeding women completing an internet survey, reported testing positive for SARS-CoV-2 (click here or ijerph-17-06766 (1)). Citation: Ceulemans M, Verbakel JY, Van Calsteren K, Eerdekens A, Allegaert K, Foulon V. SARS-CoV-2 Infections and Impact of the COVID-19 Pandemic in Pregnancy and Breastfeeding: Results from an Observational Study in Primary Care in Belgium. Int J Environ Res Public Health. 2020 Sep 17;17(18):6766. doi: 10.3390/ijerph17186766. PMID: 32957434; PMCID: PMC7559009. 

Study 494 – Case from Umbria, Italy

A woman with Covid-19 at 32 weeks gestation (click here or Lettera – Indraccolo). The pregnancy outcome was not reported. She was cared for at “Alto Tevere”, Hospital of Città di Castello, which has not previously reported cases.  Citation: Indraccolo U. A pregnant woman and the SARS-CoV-2 infection: how are barriers easily crossed? Recenti Prog Med. 2020 Apr;111(4):259-260. doi: 10.1701/3347.33190. PMID: 32319449.

Study 493 – Patient treated with ECMO in China

One of four patients treated with convalescent plasma was pregnant (click here or PIIS0012369220305717). She was aged 31, 35 weeks gestion, delivered by caesarean and following treatment with ECMO recovered. The baby died. She was initially treated at Xiaolan People’s Hospital of Zhongshan, and later transferred to the Second People’s Hospital of Zhongshan, neither of which disambiguates on GRID.ac but which must be the same as Zhongshan People’s Hospital grid.476868.3. This appears to be the sixth report of this woman, (studies 3, 57, 81, 192 & 433Citation: Zhang B, Liu S, Tan T, Huang W, Dong Y, Chen L, Chen Q, Zhang L, Zhong Q, Zhang X, Zou Y, Zhang S. Treatment With Convalescent Plasma for Critically Ill Patients With Severe Acute Respiratory Syndrome Coronavirus 2 Infection. Chest. 2020 Jul;158(1):e9-e13. doi: 10.1016/j.chest.2020.03.039. Epub 2020 Mar 31. PMID: 32243945; PMCID: PMC7195335.

11th December update – studies 491 and 492 added

Study 492 – 4 cases in Jordan

Four pregnant women with mild Covid-19 (click here or ijgo.13240). They were cared for in the King Abdullah University Hospital, Irbid, so may overlap with cases in studies 153, 435 & 463. Citation: Alsharaydeh I, Rawashdeh H, Saadeh N, Obeidat B, Obeidat N. Challenges and solutions for maternity and gynecology services during the COVID-19 crisis in Jordan. Int J Gynaecol Obstet. 2020 Aug;150(2):159-162. doi: 10.1002/ijgo.13240. Epub 2020 Jun 17. PMID: 32470178.

Study 491 – Abortion case in New York

An asymptomatic woman with sickle cell disease undergoing abortion by D&E at 15 weeks developed post operative pneumonia and tested positive for SARS-CoV-2 (click here or PIIS0010782420301530). From author affiliations she was cared for at Columbia University Irving Medical Center, previous reports from which (studies 14, 27, 136, & 271) have not included pregnancy termination cases. Citation: Fang NZ, Castaño PM, Davis A. A hospital-based COVID-19 abortion case in the early phase of the pandemic. Contraception. 2020;102(2):137-138. doi:10.1016/j.contraception.2020.05.005

8th December update – studies 478 to 490 added

Study 490 – Case in USA

A woman with Covid-19 was delivered by Caesarean at 35 weeks (click here or acc-14-e01303). She was cared for at Boston Medical Center, Boston, Massachusetts, so might be included in study 292. Citation: Norris MC, Kalustian A, Salavati S. Epidural Blood Patch for Postdural Puncture Headache in a Patient With Coronavirus Disease 2019: A Case Report. A&A Practice. 2020 Aug;14(10):e01303. DOI: 10.1213/xaa.0000000000001303.

Study 489 – Case in China

A woman contracted Covid-19 at 35 weeks, and was delivered by Caesarean (click here or BMJ-37-226). She recovered. From author affiliations she was cared for at Chongqing Three Gorges Central Hospital, grid.477128.f Chongqing. Other features also suggest this and study 252 describe the same woman. Citation: Liao X, Yang H, Kong J, Yang H. Chest CT Findings in a Pregnant Patient with 2019 Novel Coronavirus Disease. Balkan Med J. 2020;37(4):226-228. doi:10.4274/balkanmedj.galenos.2020.2020.3.89

Study 488 – 20 cases detected by screening in USA

Four hospitals associated with Mass General Brigham Health, Massachusetts, tested 757 women admitted in labour between April 18th & May 5th. 20 were positive for SARS-CoV-2 (click here or S0899823X2000255Xa). This organisation has not previously reported cases. Citation: Goldfarb IT, Diouf K, Barth WH, et al. Universal SARS-CoV-2 testing on admission to the labor and delivery unit: Low prevalence among asymptomatic obstetric patients. Infect Control Hosp Epidemiol. 2020;41(9):1095-1096. doi:10.1017/ice.2020.255

Study 487 – 5 cases in USA

There were 79/1,811 SARS-CoV-2 positive tests between April 27, and May 18, in a big hospital. Five were in pregnant women (click here or S0899823X2000358Xa). The hospital is unnamed, but probably affiliated with Virginia Commonwealth University, Richmond, Virginia,. Citation: : Sastry SR, et al. (2020). Universal screening for the SARS-CoV-2 virus on hospital admission in an area with low COVID-19 prevalence. Infection Control & Hospital Epidemiology, https://doi.org/10.1017/ice.2020.358

Study 486 – 37 cases in Chile

37/583 pregnant women had a positive test for SARS CoV-2 (click here or journal.pone.0239887). Two women required ventilation. None died. Two babies tested positive. One baby, who tested negative, died. The study was conducted in Clınica Davila, Santiago, which has not previously reported cases. Citation: Dı´az-Corvillo´n P, Mo¨nckeberg M, Barros A, Illanes SE, Soldati A, Nien J-K, et al. (2020) Routine screening for SARS CoV-2 in unselected pregnant women at delivery. PLoS ONE 15(9): e0239887. https://doi.org/10.1371/journal.pone.0239887

Study 485 – 3 cases in Spain

Three pregnant women with Covid-19 (click here or main (9) In Spanish). From author affiliations cared for at Hospital Universitario Materno-Infantil de Jaén, Jaén, so may overlap with study 158. Citation: Hijona Elósegui JJ, Carballo García AL, Fernández Risquez AC. New evidences that discard the possible vertical transmission of SARS-CoV-2 during pregnancy. Nuevas evidencias que descartan la posible transmisión vertical del SARS-CoV-2 durante la gestación. Med Clin (Barc). 2020;155(7):313-314. doi:10.1016/j.medcli.2020.05.021

Study 484 – Case report in Italy

A pregnant woman with Covid-19 also had a pulmonary embolus (click here or PIIS0049384820301389). She was cared for in Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, so probably included in the Lombardy series. Citation: Martinelli I, Ferrazzi E, Ciavarella A, Erra R, Iurlaro E, Ossola M, Lombardi A, Blasi F, Mosca F, Peyvandi F. Pulmonary embolism in a young pregnant woman with COVID-19. Thromb Res. 2020 Jul;191:36-37. doi: 10.1016/j.thromres.2020.04.022. Epub 2020 Apr 20. PMID: 32371163; PMCID: PMC7169886.

Study 483 – 21 cases in Italy

21 women with Covid-19 during pregnancy (click here or R02Y2020N11A1248). From author affiliations cared for at Spedali civili of Brescia, Brescia, so likely included in the various Lombardy series. Citation: Giannini A, Mantovani A, Vezzoli C, Franchini D, Finazzi P. Lung ultrasound for pregnant women admitted to ICU for COVID-19 pneumonia. Minerva Anestesiol. 2020 Nov;86(11):1248-1249. doi: 10.23736/S0375-9393.20.14726-6. Epub 2020 May 29. PMID: 32486608.

Study 482 – Case in Iraq

A pregnant woman with Covid-19 at 28 weeks went into preterm labour and delivered at 30 weeks (click here or AsianPacJReprod000-415713_113251). The baby was not infected. From author affiliations she was cared for at Al-Kadhemia Teaching Hospital, Baghdad. This is the first report from Iraq. Citation: Al-Kuraishy, H., Al-Maiahy, T., Al-Gareeb, A., Musa, R., & Ali, Z. (2020). COVID-19 pneumonia in an Iraqi pregnant woman with preterm delivery. Asian Pacific Journal of Reproduction, 9(3). https://doi.org/10.4103/2305-0500.282984

Study 481 – Puerperal skin manifestations of Covid-19

A woman with Covid-19 developed a skin rash 7 days post partum (click here or ijd.14919). She was cared for at San Raffaele Hospital, Milan, Italy, so may have been included in the various Lombardy series. Citation: Paolino, G., Canti, V., Mercuri, S.R., Rovere Querini, P., Candiani, M. and Pasi, F. (2020), Diffuse cutaneous manifestation in a new mother with COVID‐19 (SARS‐Cov‐2). Int J Dermatol, 59: 874-875. https://doi.org/10.1111/ijd.14919

Study 480 – Puerperal case in USA

A woman with puerperal Covid-19 (click here or 10-1055-s-0040-1712926). From author affiliations she was cared for at University of Alabama at Birmingham, Alabama, which has not previously reported cases. Citation: Sinkey RG, Rajapreyar I, Robbins LS, et al. Heart Failure with Preserved Ejection Fraction in a Postpartum Patient with Superimposed Preeclampsia and COVID-19. AJP Rep. 2020;10(2):e165-e168. doi:10.1055/s-0040-1712926

Study 479 – Patient in the Netherlands

A pregnant woman with systemic lupus erythematosus, using long-term corticosteroids, contracted Covid-19 (click here or bcr-2020-235581). She gave birth normally and the baby was unaffected. She was cared for at Reinier de Graaf Gasthuis, Delft, which has not previously reported cases. Citation: Grimminck K, Santegoets LAM, Siemens FC, et al. BMJ Case Rep 2020;13:e235581. doi:10.1136/bcr-2020-235581

Study 478 – Case report from Caracas, Venezuela

A woman tested postive for SARS-CoV-2 during the pregnancy, and had mild symptoms, but had recovered by the time she was delivered by Caesarean on March 31st (click here or main (8)). The baby tested negative. The birth hospital is not named. Citation: Forero-Peña DA, Rodríguez MI, Flora-Noda DM, et al. The first pregnant woman with COVID-19 in Venezuela: Pre-symptomatic transmission. Travel Med Infect Dis. 2020;36:101805. doi:10.1016/j.tmaid.2020.101805

7th December – studies 464 to 475 added

Study 475 – 308 cases from Mexico

Using open data from the Mexican Ministry of Health up to May 17th, 7/308 pregnant women with Covid-19 had died (click here or ijgo.13250). This report will overlap with study 340. Citation: Lumbreras‐Marquez, M.I., Campos‐Zamora, M., Lizaola‐Diaz de Leon, H. and Farber, M.K. (2020), Maternal mortality from COVID‐19 in Mexico. Int J Gynecol Obstet, 150: 266-67. https://doi.org/10.1002/ijgo.13250

Study 474 – 12 cases from Turkey

No SARS-CoV-2 was detected in vaginal fluid of 12 pregnant women with COVID-19 (click here or SARS CoV 2 is not present in the vaginal fluid of pregnant women with COVID 19 (1)). All had mild symptoms and none needed critical care. From author affiliations they were cared for at Sakarya Training and Research Hospital, Sakarya, Turkey, which has not previously reported cases. Citation: Mehmet Musa Aslan , Hilal Uslu Yuvacı , Osman Köse , Hande Toptan , Nermin Akdemir , Mehmet Köroğlu , Arif Serhan Cevrioğlu & Selçuk Özden (2020): SARS-CoV-2 is not present in the vaginal fluid of pregnant women with COVID-19, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1793318

Study 473 – Thrombocytopaenia & mild Covid-19

Three pregnant wowen with mild Covid-19 also had thrombocytopaenia (click here or main (7)). From author affiliations they were cared for at Antoine-Beclere Hospital, Paris, so may overlap with studies 217 and 326. Citation: Le Gouez A, Vivanti AJ, Benhamou D, Desconclois C, Mercier FJ. Thrombocytopenia in pregnant patients with mild COVID-19. Int J Obstet Anesth. 2020;44:13-15. doi:10.1016/j.ijoa.2020.05.010

Study 472 – 16 cases from China

These 16 pregnant women with COVID‐19 up until February 16, 2020 in Wuhan Union Hospital (click here or ijgo.13236) have probably been reported before. Citation: Zeng Y, Lin L, Yan Q, Wei W, Xiang Yang B, Huang R, He F, Chen D. Update on clinical outcomes of women with COVID-19 during pregnancy. Int J Gynaecol Obstet. 2020 Aug;150(2):264-266. doi: 10.1002/ijgo.13236. Epub 2020 Jun 9. PMID: 32438521.

Study 471 – 12 cases from China

12 pregnant women with Covid-19 (click here or 1-s2.0-S0890623820302677-main). They were cared for at Renmin Hospital of Wuhan University grid.412632.0 and the near hospitals in Wuhan City, Hubei Province, China. They have therefore probably already been reported. Citation: Cuifang Fan, No obviously adverse pregnancy complications and outcomes of the recovered pregnant women from COVID-19. Letter. Reproductive Toxicology, https://doi.org/10.1016/j.reprotox.2020.11.008

Study 470 – Screening in Madrid, Spain

86 seropositive pregnant women were detected out of 759 tested between February 28th and May 10th (click here or pone.0243029). The hospital was Hospital Universitario 12 de Octubre, so they may overlap with those in studies 205 and 458. Citation: Villalaı´n C, Herraiz I, Luczkowiak J, Pe´rez-Rivilla A, Folgueira MD, Mejı´a I, et al. (2020) Seroprevalence analysis of SARS-CoV-2 in pregnant women along the first pandemic outbreak and perinatal outcome. PLoS ONE 15(11): e0243029. https://doi.org/10.1371/journal.pone.0243029

Study 469 – Case report from Turkey

An asymptomatic woman with SARS-CoV-2 delivered by Caesarean (click here or jog.14584). Cared for at Umraniye Training and Research Hospital Emergency Obstetrics Clinic, Istanbul, which has not previously reported cases. Citation: Palalioglu, R.M., Mahammadaliyeva, A., Erbiyik, H.I. and Muhcu, M. (2020), COVID‐19 in third trimester may not be as scary as you think, it can be innocent: Evaluating vertical transmission from a COVID‐19 positive asymptomatic pregnant woman with early membrane rupture. J. Obstet. Gynaecol. Res.. https://doi.org/10.1111/jog.14584

Study 468 – 4 patients from Canada

Four pregnant patients with SARS-CoV-2 were identified by screening (click here or birt.12520). It’s not possible to determine from author affiliations which centre in Toronto, cared for them, so some may have been included in studies 48 and 103. Citation: Mei-Dan, E, Satkunaratnam, A, Cahan, T, Leung, M, Katz, K, Aviram, A. Questionnaire‐based vs universal PCR testing for SARS‐CoV‐2 in women admitted for delivery. Birth. 2020; 00: 1– 8. https://doi.org/10.1111/birt.12520

Study 467 – 137 cases from West French Guiana

Of 137 pregnant women with SARS-CoV-2 infection, 3 required ITU admission but none died (click here or hcini ejog). There were 3 terminations and 7 stillbirths. Four babies were infected. Patients were cared for at West French Guiana Hospital Center (Centre Hospitalier de l’Ouest Guyanais), which has not previously reported cases. Citation: Hcini N, Maamri F, Picone O, Carod J-Francois, Lambert V, Mathieu M, Carles G, Pomar L, Maternal, fetal and neonatal outcomes of large series of SARS-CoV-2 positive pregnancies in peripartum period: a single-center prospective comparative study, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.11.068

Study 466 – Case report from USA

A woman with Covid-19 required ventilation (click here or Coronavirus_Disease_2019__COVID_19__Related.74). She survived. From author affiliations she was cared for in North Shore University Hospital, Manhasset, New York, which means she might be included in study 179. Citation: Gulersen, Moti MD, MSc; Staszewski, Cara MD; Grayver, Evelina MD; Tam Tam, Hima MD; Gottesman, Eric MD; Isseroff, Donnie MD; Rochelson, Burton MD; Bonanno, Clarissa MD Coronavirus Disease 2019 (COVID-19)–Related Multisystem Inflammatory Syndrome in a Pregnant Woman, Obstetrics & Gynecology: December 3, 2020 – Volume Latest Articles – Issue – 10.1097/AOG.0000000000004256 doi: 10.1097/AOG.0000000000004256 

Study 465 – Case report from China

A woman with Covid-19 at 34 weeks cared for at Renmin Hospital of Wuhan University (click here or ijgo.13232). Probably included in a multiple previous studies. Citation: Yu, Y., Fan, C., Bian, J. and YinShen, (2020), Severe COVID‐19 in a pregnant patient admitted to hospital in Wuhan. Int J Gynecol Obstet, 150: 262-263. https://doi.org/10.1002/ijgo.13232

Study 464 – Lung ultrasound in 4 cases

Four women with Covid-19 underwent lung ultrasound (click here or uog.22055). From author affiliations they were cared for at Fondazione Policlinico Universitario A. Gemelli, IRCCS, Rome, Italy, and may overlap with those in studies 76 and 78. Citation: Buonsenso, D., Raffaelli, F., Tamburrini, E., Biasucci, D.G., Salvi, S., Smargiassi, A., Inchingolo, R., Scambia, G., Lanzone, A., Testa, A.C. and Moro, F. (2020), Clinical role of lung ultrasound for diagnosis and monitoring of COVID‐19 pneumonia in pregnant women. Ultrasound Obstet Gynecol, 56: 106-109. https://doi.org/10.1002/uog.22055

6th December – studies 452 to 463 added

Study 463 – Case report from Jordan

A woman with Covid-19 (click here or 925512) was treated at King Abdullah University Hospital Irbid, Jordan, on March 28, 2020. She may therefore have been reported in studies 153 and 435. Citation: Bani Hani D.A. et al.: Successful anesthetic management in cesarean section for Pregnant Woman with COVID-19. Am J Case Rep, 2020; 21: e925512

Study 462 – Normal birth in Italy

A woman tested positive at 40 weeks gestation (click here or mjhid-12-1-e2020033). She gave birth normally. The baby tested negative. From author affiliations she gave birth at Santa Maria della Misericordia Hospital, Perugia, which has not previously reported cases. Citation: De Socio G.V., Malincarne L., Arena S., Troiani S., Benedetti S., Camilloni B., Epicoco G., Mencacci A., Francisci D. Delivery in asymptomatic italian woman with SARS-CoV-2 infection. Mediterr J Hematol Infect Dis 2020, 12(1): e2020033, DOI: http://dx.doi.org/10.4084/MJHID.2020.033&nbsp;

Study 461 – Maternal death in Iran

A woman contracted Covid-19 at 23 weeks with twins (click here or 29688-Article Text-117866-1-10-20200408). She died with the twins undelivered. She was cared for at Imam Hossein
Medical and Educational Center, Shahid Beheshti University of Medical Sciences, Tehran, which has not previously reported cases. Citation: Shojaei S, Kouchek M, Miri MM, Salarian S, Sistanizad M, Ariana S, et al. Twin pregnant woman with COVID-19: a case report. J Cell Mol Anesth. 2020;5(1):43-6

Study 460 – Severe case from Italy

A woman with Covid-19 at 27 weeks required 15 days ventilation (click here or sv-YX051401). She recovered and the baby remained undelivered. She was cared for in Azienda Ospedaliera Santa Croce e Carle, Cuneo, which has not previously reported cases. Citation: Luigi Barile, Martina Cerrano, Alessandro Locatelli, Andrea Puppo, Anna F. Signorile, Nicoletta Barzaghi. Prone Ventilation in a 27 Week Pregnant Woman with COVID-19 Severe ARDS. Signa Vitae. 2020. 16(1);199-202.

Study 459 – 6 cases from China

6 pregnant women with Covid-19 (click here or PIIS0163445320302929). Three required ITU admission and ventilation, and one ECMO. They all survived. The patients were cared for in the First Affiliated Hospital of Jinan University grid.412601.0, Guangzhou, Guangdong. This suggests possible overlap with studies 3, 57 and 81, all of which also reported a pregnant woman treated with ECMO. Citation: Huang, Wenhui et al. Unfavorable outcomes in pregnant patients with COVID-19.Journal of Infection, Volume 81, Issue 2, e99 – e101

Study 458 – 2 cases from Spain

2/203 women screened on admission in labour at Hospital Universitario 12 de Octubre in Madrid, tested positive (click here or [16193997 – Journal of Perinatal Medicine] Universal screening for SARS-CoV-2 before labor admission during Covid-19 pandemic in Madrid). Citation: Herraiz, I., Folgueira, D., Villalaín, C., Forcén, L., Delgado, R., & Galindo, A. (2020). Universal screening for SARS-CoV-2 before labor admission during Covid-19 pandemic in Madrid, Journal of Perinatal Medicine, 48(9), 981-984. doi: https://doi.org/10.1515/jpm-2020-0236

Study 457 – 94 cases in USA

94 confirmed or suspected cases of Covid-19 in pregnancy (click here or s-0040-1712529). From author affiliations they were cared for at Icahn School of Medicine at Mount Sinai, so overlap with studies 86, 119, 131 and 455 is likely. Citation: Fox NS, Melka S. COVID-19 in Pregnant Women: Case Series from One Large New York City Obstetrical Practice. Am J Perinatol. 2020 Aug;37(10):1002-1004. doi: 10.1055/s-0040-1712529. Epub 2020 May 21. PMID: 32438425; PMCID: PMC7416214.

Study 456 – 9 cases from Senegal

Nine pregnant women with Covid-19 from March 2 to May 15, were identified (click here or 58). They all recovered. This is the first report from Senegal. Citation: Abdoul Aziz Diouf et al. Clinical characteristics and outcomes of COVID-19 infection in nine pregnant women: a report from a sub-Saharan African country, Senegal. Pan African Medical Journal. 2020;35(2):58. [doi: 10.11604/pamj.supp.2020.35.2.23736]

Study 455 – Case report from USA

A woman with Covid-19 at 30 weeks improved after Caesarean delivery (click here or e236290.full). From author affiliations she was cared for at Icahn School of Medicine at Mount Sinai, New York, so she might be included in studies 86, 119, and 131. Citation: Oliva M, Hsu K, Alsamarai S, et al. Clinical improvement of severe COVID-19 pneumonia in a pregnant patient after caesarean delivery. BMJ Case Reports CP 2020;13:e236290.

Study 454 – Follow up of four patients in Study 6

The four women who were undelivered at the time of reporting study 6 recovered, but their pregnancy outocmes are still not reported (Click here or ajr.20.23247). Citation: Lin Li, Dehan Liu, and Lian Yang. Follow-Up Information About the Four Pregnant Patients With Coronavirus Disease (COVID-19) Pneumonia Who Were Still in the Hospital at the End of Our Study. American Journal of Roentgenology 2020 215:1, W17-W18

Study 453 – Lung ultrasound in 2 pregnant women with Covid-19, Spain

The lung ultrasound appearances of two pregnant women with Covid-19 (click here or jum.15419). From author affiliations they were cared for in Hospital General Universitario de Alicante, which has not previously reported cases. Citation: Gil‐Rodrigo, A., Llorens‐Soriano, P. and Ramos‐Rincón, J.‐M. (2020), Ultrasound in Pregnant Women With Suspected COVID‐19 Infection. J Ultrasound Med. https://doi.org/10.1002/jum.15419

Study 452 – Maternal death in Turkey

A woman with Covid-19 at 31 weeks gestation died (click here or 202587-454095-1-PB). The baby, born by Caesarean also died. From author affiliations they were cared for in University Kocaeli Derince Training and Research Hospital, Kocaeli. The case may have been included in studies 244 and 382. Citation: K. Uzel, I. V. Lakhno A MORTAL CASE OF CORONAVIRUS DISEASE IN A PREGNANT DIABETIC WOMAN. CLINICAL CASE Reproductive Endocrinology, ISSN: 2411-1295, Vol: 0, Issue: 52, Page: 33-36

5th December – studies 438 to 451 added

Study 451 – 24 cases, 3 severe, from UK

Of 24 pregnant or immediately post-partum patients with COVID-19, three required prolonged admittion to ICU (click here or 1751143720947547). They were cared for at Chelsea and Westminster NHS Foundation Trust in London, which has not previously reported cases. However they were probably included in study 92. The three ICU cases were probabaly incuded in the various ICNARC reports. Citation: Morton S, Lamont H, Silvey N, et al. Adult intensive care unit admissions with severe COVID-19 infection following emergency Caesarean section deliveries: A case series. Journal of the Intensive Care Society. August 2020. doi:10.1177/1751143720947547

Study 450 – Case report from China

This woman with Covid-19 who delivered in Maternal and Child Health Hospital of Hubei Province on April 5, 2020 (click here or medi-99-e21335) must have been included in many of the Wuhan series.. Citation: Peng J, Li R, Yin H, et al. A case report of a pregnant woman infected with coronavirus disease 2019 pneumonia. Medicine (Baltimore). 2020;99(30):e21335. doi:10.1097/MD.0000000000021335

Study 449 – 11 cases from Israel

11 pregnant women with SARS-CoV-2 infection cared for at Sheba Medical Center, Tel-Hashomer, Ramat Gan, (click here or Mohr-Sasson2020_Article_LaboratoryCharacteristicsOfPre). They may overlap with cases in studies 278 and 330. Citation: Mohr-Sasson A, Chayo J, Bart Y, Meyer R, Sivan E, Mazaki-Tovi S, Yinon Y. Laboratory characteristics of pregnant compared to non-pregnant women infected with SARS-CoV-2. Arch Gynecol Obstet. 2020 Sep;302(3):629-634. doi: 10.1007/s00404-020-05655-7. Epub 2020 Jun 22. PMID: 32572616; PMCID: PMC7307945.

Study 448 – a case with polymorphic eruption of pregnancy

A woman who tested positive for SARS-CoV-2 at 39 weeks developed polymorphic eruption of pregnancy 10 days after giving birth (click here or dth.14117). The hospital is not named but from author affiliations is affiliated with Sapienza University of Rome, Italy. Citation: Proietti I, Bernardini N, Tolino E, Mambrin A, Balduzzi V, Marchesiello A, Michelini S, Skroza N, Potenza C. Polymorphic eruption of pregnancy as a possible COVID-19 manifestation. Dermatol Ther. 2020 Aug 1:e14117. doi: 10.1111/dth.14117. Epub ahead of print. PMID: 32737915; PMCID: PMC7436318.

Study 447 – 29 cases from China

29 women with Covid-19 delivered 30 babies (one set of twins) between January 30 and March 10 (click here or journal.pmed.1003195 (1)). They were cared for in Renmin Hospital, Wuhan University, grid.412793.a and Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology grid.412793.a. They likely overlap with many previous reports from Wuhan. Citation: Wu YT, Liu J, Xu JJ, Chen YF, Yang W, Chen Y, Li C, Wang Y, Liu H, Zhang C, Jiang L, Qian ZX, Kawai A, Mol BW, Dennis CL, Xiong GP, Cheng BH, Yang J, Huang HF. Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China. PLoS Med. 2020 Jul 28;17(7):e1003195. doi: 10.1371/journal.pmed.1003195. PMID: 32722722; PMCID: PMC7386573.

Study 446 – A woman treated with ECMO in UK

A woman with severe Covid-19 was delivered by Caesarean at 39 weeks and required ventilation and ECMO (click here or demirjian2020). The baby tested positive and had clinical disease. Both eventually recovered. The birth took place at North Middlesex University Hospital NHS Trust, London, so although not cited, this is also case 1 in study 93. Citation: Demirjian A, Singh C, Tebruegge M, Herbert R, Draz N, Mirfenderesky M, Jones V, Hinstridge P, Seneviratne R, Myers R, Ellis J, Miah S, Meadows CI, Kenny J, Alonso A, Handforth J, Perkins S, Butler M, Blackburn F, Douthwaite S, Pillay D, Chand M, Zambon M. Probable Vertical Transmission of SARS-CoV-2 Infection. Pediatr Infect Dis J. 2020 Sep;39(9):e257-e260. doi: 10.1097/INF.0000000000002821. PMID: 32658096.

Study 445 – Miscarriage in Pakistan

A woman with Covid-19 miscarried at 11 weeks (click here or PIIS0163445320305879). She recovered. It is not possible to deduce which hospital cared for her from author affiliations. However, this is the first report from Islamabad. Citation: Rana MS, Usman M, Alam MM, Khalid A, Ikram A, Salman M, Zaidi SSZ, Faryal R, Qadir M, Umair M, Roohullah, Sufian MM. First trimester miscarriage in a pregnant woman infected with COVID-19 in Pakistan. J Infect. 2020 Sep 5:S0163-4453(20)30587-9. doi: 10.1016/j.jinf.2020.09.002. Epub ahead of print. PMID: 32896525.

Study 444 – SARS-CoV-2 detected in breast milk

A breast milk sample from an asymptomatic woman who tested positive for SARS-CoV-2 at birth, also tested positive (click here or 10.1089@bfm.2020.0161). The neonate tested negative and remained well. She was cared for Ankara City Hospital, Ankara, Turkey. The case may have been included in studies 95, 203 and 244. Citation: Bastug A, Hanifehnezhad A, Tayman C, Ozkul A, Ozbay O, Kazancioglu S, Bodur H. Virolactia in an Asymptomatic Mother with COVID-19. Breastfeed Med. 2020 Aug;15(8):488-491. doi: 10.1089/bfm.2020.0161. Epub 2020 Jul 1. PMID: 32614251.

Study 443 – No SARS-CoV-2 detected in colostrum

Seven women with SARS-CoV-2 positive tests at delivery gave samples of colostrum, which all tested negative (click here or bfm.2020.0183). From author affiliations the hospital was Puerta de Hierro-Majadahonda University Hospital, Madrid, Spain, so they likely overlap with cases in studies 125, 151, 177, and 196. Citation: Marín Gabriel MÁ, Malalana Martínez AM, Marín Martínez ME, Anel Pedroche J. Negative Transmission of SARS-CoV-2 to Hand-Expressed Colostrum from SARS-CoV-2-Positive Mothers. Breastfeed Med. 2020 Aug;15(8):492-494. doi: 10.1089/bfm.2020.0183. Epub 2020 Jul 9. PMID: 32644841.

Study 442 – 30 cases from China

30 pregnant women with Covid-19 treated in th Central Hospital of Wuhan grid.440160.7, China, from December 8, 2019 to April 1, 2020 are reported (click here or ijgo.13265). They overlap with those in study 39 and many other Wuhan series. Citation: Wang Z, Wang Z, Xiong G. Clinical characteristics and laboratory results of pregnant women with COVID-19 in Wuhan, China. Int J Gynaecol Obstet. 2020 Sep;150(3):312-317. doi: 10.1002/ijgo.13265. Epub 2020 Jul 3. PMID: 32510581; PMCID: PMC7496890.

Study 441 – 69 cases from India

69 women with SARS-CoV-2 had one abortion and four stillbirths (click here or Anand2020_Article_ClinicalProfileViralLoadManage). Of 65 live births, 7 neonates tested positive. There were two neonatal deaths both of whom tested negative. Two mothers died. From author affiliations they were cared for at Vardhman Mahavir Medical College & Safdarjung Hospital, New Delhi, which has not previously reported cases. Citation: Anand P, Yadav A, Debata P, Bachani S, Gupta N, Gera R. Clinical profile, viral load, management and outcome of neonates born to COVID 19 positive mothers: a tertiary care centre experience from India. Eur J Pediatr. 2020 Sep 10:1–13. doi: 10.1007/s00431-020-03800-7. Epub ahead of print. PMID: 32910210; PMCID: PMC7482055.

Study 440 – Mother and obstetrician deaths in Nigeria

This predominantly opinion piece mentions a mother who died of Covid-19 in Lagos State University Teaching Hospital, who has not been reported elsewhere (click here or ijgo.13325). The article also refers to a newspaper report of an obstetrician who died of Covid-19 having been infected in his private clinic (added as report 274 here). Citation: Ijarotimi OA, Ubom AE, Olofinbiyi BA, Kuye-Kuku T, Orji EO, Ikimalo JI. COVID-19 and obstetric practice: A critical review of the Nigerian situation. Int J Gynaecol Obstet. 2020 Jul 22. doi: 10.1002/ijgo.13325. Epub ahead of print. PMID: 32698245.

Study 439 – One case from China

One pregnant woman in this series (click here or ijmsv17p2187). No further details. Hunan province is adjacent to Hubei province which contains the City of Wuhan. The authors are affiliated with hospitals in Changsha, Chenzhou, Loudi and Yiyang, all cities in Hunan. No previous cases have been reported from this province. Citation: Tao PY, Leng L, Liu K, Zhou RH, Hu YC, Wu SJ, Xiao YD, Liu J. Determination of risk factors for predicting the onset of symptoms in asymptomatic COVID-19 infected patients. Int J Med Sci. 2020 Aug 6;17(14):2187-2193. doi: 10.7150/ijms.47576. PMID: 32922180; PMCID: PMC7484673.

Study 438 – Maternal death in Turkey

A 22 year old woman died from Covid-19 at 32 weeks (click here or 42399_2020_Article_508). The baby, delivered by Caesarean, tested negative and survived. The mother had been treated with extra-corporal cytokine hemoadsorption therapy to remove inflammatory cytokines from the circulation. From author affliations she was cared for in Uşak Training and Research Hospital, Uşak,  which has not previously reported cases. Citation: Karabulut Keklik ES, Dal H, Bozok Ş. Cytokine Hemoadsorption in the Management of a Pregnant Woman with COVID-19 Pneumonia: Case Report [published online ahead of print, 2020 Sep 16]. SN Compr Clin Med. 2020;1-5. doi:10.1007/s42399-020-00508-5

4th December – studies 434 to 437 added

Study 437 – Case report from USA

A woman with Covid-19 at 34 weeks was delivered by emergency Caesarean for an abnormal CTG trace (click here or e625.full). The baby tested negative. From author affiliations the hospital was part of the NorthShore University Health System, Evanston, Illinois, which has not previously reported cases. Citation: Suresh SC, MacGregor CA, Ouyang DW. Urgent Cesarean Delivery Following Nonstress Test in a Patient with COVID-19 and Pregestational Diabetes. Neoreviews. 2020 Sep;21(9):e625-e630. doi: 10.1542/neo.21-9-e625. PMID: 32873658.

Study 436 – Case report from Korea

On March 6, 2020, a 28-year old woman with Covid-19 gave birth to a girl by Caesarean in Daegu Fatima Hospital at 37 weeks (click here or cep-2020-00850). This is probably the same patient as reported in study 22. Citation: Lee EK, Kim WD, Lee DW, Lee SA. Management of the first newborn delivered by a mother with COVID-19 in South Korea. Clin Exp Pediatr. 2020;63(9):373-375. doi:10.3345/cep.2020.00850

Study 435 – 2 patients delivered in a burns unit in Jordan

Two women with mild Covid-19 (but no burns) were delivered by caesarean section in a burns facility (click here or Altal2020_Article_PreparingTheBurnsUnitToAccommo). Neither baby was infected. All recovered. The hospital was King Abdullah University Hospital in Irbid, which may also be where the patient in study 153 delivered. The clinical features suggest that one of these cases is also that case.  Citation: Altal O, Bani Hani D, Aleshawi A, Alhowary AA, Obeidat B, Bani-Ata M. Preparing the Burns Unit to Accommodate Vaginal Delivery and Cesarean Section for Pregnant Women with COVID-19: A Successful Experience from Jordan. Adv Ther. 2020 Oct;37(10):4049-4053. doi: 10.1007/s12325-020-01457-0. Epub 2020 Aug 27. PMID: 32852673; PMCID: PMC7450677.

Study 434 – 242 women and 248 babies from Spain

This series from the Spanish Neo-COVID-19 Research Group seems to describe the same patients as those reported in study 390 (click here or Maternal,_Perinatal_and_Neonatal_Outcomes_With.2). There is also probably overlap with those in study 264b. Citation: Marín Gabriel MA, Reyne Vergeli M, Caserío Carbonero S, Sole L, Carrizosa Molina T, Rivero Calle I, Cuadrado Pérez I, Álvarez Fernández B, Forti Buratti A, Fernández-Cañadas Morillo A; Neo-COVID-19 Research Group. Maternal, Perinatal and Neonatal Outcomes With COVID-19: A Multicenter Study of 242 Pregnancies and Their 248 Infant Newborns During Their First Month of Life. Pediatr Infect Dis J. 2020 Dec;39(12):e393-e397. doi: 10.1097/INF.0000000000002902. PMID: 32947599.

3rd December – studies 428 to 433 added

Study 433 – pregnant woman with Covid-19 recovering after ECMO, China

A woman with Covid-19 at 35 weeks was ventilated, delivered by Caesarean, and treated with ECMO (click here or PIIS0147956320303599). She survived. The baby outcome is not reported in the present paper. She was cared for in Zhongshan People’s Hospital grid.476868.3, Zhongshan. It seems likely that this is the same case as reported in studies 3, 57, 81 and 192. In those papers the baby is reported to have died. The present paper cites none of those papers. Citation: Hou, Liusheng et al. First successful treatment of a COVID-19 pregnant woman with severe ARDS by combining early mechanical ventilation and ECMO. Heart & Lung: The Journal of Cardiopulmonary and Acute Care, Volume 0, Issue 0 https://doi.org/10.1016/j.hrtlng.2020.08.015 0147-9563

Study 432 – case report from Pakistan

A woman with Covid-19 was delivered by Caesarean (click here or JPAM_Vol_14_Issue2_p_1121-1123 (1)). The baby tested negative. Both recovered. She was cared for in Aziz Bhatti Shaheed Teaching Hospital in Gujrat, which has not previously reported cases. Citation: Tarar SH, Atta H, Khalid M, et al. A Case Report of Pregnant Lady having COVID-19 Delivered via Cesarean Section in Tertiary Care Hospital in Pakistan. J Pure Appl Microbiol. 2020;14(2):1121-1123. doi: 10.22207/JPAM.14.2.06

Study 431 – Case report from India

An asymptomatic woman who tested positive for SARS-CoV-2 was delivered by Caesarean at 38 weeks (click here or fmaa048). The asymptomatic baby was isolated and artificially fed, but tested positive at 48 hours. From author affiliations the hospital was S.N. Children Hospital, Prayagraj, Uttar Pradesh, which has not previously reported cases. Citation: Singh MV, Shrivastava A, Maurya M, Tripathi A, Sachan R, Siddiqui SA. Vertical Transmission of SARS-CoV-2 from an Asymptomatic Pregnant Woman in India. J Trop Pediatr. 2020 Sep 25:fmaa048. doi: 10.1093/tropej/fmaa048. Epub ahead of print. PMID: 32974677.

Study 430 – Screening in Italy

Of 333 pregnant women screened in four hospitals in Genoa, from April 1 to April 30, only one symptomatic patient (0.3%) and six asymptomatic ones (1.8%) tested positive (click here or JMV-9999-na). The hospitals were San Martino, G. Gaslini, Galliera and Villa Scassi – ASL3 Hospital, none of which have previously reported cases. Citation: Massarotti C, Adriano M, Cagnacci A, et al. Asymptomatic SARS-CoV-2 infections in pregnant patients in an Italian city during the complete lockdown [published online ahead of print, 2020 Aug 25]. J Med Virol. 2020;10.1002/jmv.26458. doi:10.1002/jmv.26458

Study 429 – Ovarian vein thrombosis and COVID‑19

A 26-year-old woman with Covid-19 at 8 weeks gestation also developed a right ovarian vein thrombosis  (click here or Mohammadi2020_Article_OvarianVeinThrombosisAfterCoro). The pregnancy outcome was not reported. She was cared for at Besat Hospital in Sanandaj, Iran, which has not previously reported cases. Citation: Mohammadi S, Abouzaripour M, Hesam Shariati N, Hesam Shariati MB. Ovarian vein thrombosis after coronavirus disease (COVID-19) infection in a pregnant woman: case report. J Thromb Thrombolysis. 2020 Oct;50(3):604-607. doi: 10.1007/s11239-020-02177-6. PMID: 32514763; PMCID: PMC7278233. 

Study 428 – Postnatal case from Italy

A 34-year-old pregnant woman gave birth on 9 August at the “Mater Dei” hospital, Bari, Apulia region, which has not previously reported cases (click here or main (6)). Both mother and baby contracted Covid-19 postnatally. Citation: Lenoci G, Galante D, Ceci E, et al. Sars-CoV-2 isolation from a 10-day-old newborn in Italy: A case report. IDCases. 2020;22:e00960. doi:10.1016/j.idcr.2020.e00960

2nd December – studies 419 to 427 added

Study 427 – 5 placentas from SARS-CoV-2 pregnancies

Five placentas from pregnancies positive for SARS-CoV-2 are described (click here or 511324). From author affiliations the pregnancies had been cared for at University Hospital Basel, Basel, Switzerland, which has not previously reported cases. Citation: Menter T, Mertz KD, Jiang S, Chen H, Monod C, Tzankov A, Waldvogel S, Schulzke SM, Hösli I, Bruder E. Placental Pathology Findings during and after SARS-CoV-2 Infection: Features of Villitis and Malperfusion. Pathobiology. 2020 Sep 18:1-9. doi: 10.1159/000511324. Epub ahead of print. PMID: 32950981; PMCID: PMC7573905.

Study 426 – Pregnancy, Covid-19 & sickle cell disease in Brazil

A pregnant woman with sickle cell disease contracted Covid-19 at 28 weeks gestation (click here or 2531-1379-htct-42-03-0212). She recovered and the pregnancy is ongoing. From author affiliations she was cared for in Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, which has not previously reported cases. Citation: JUSTINO, Caio Cesar et al. COVID-19 as a trigger of acute chest syndrome in a pregnant woman with sickle cell anemia. Hematol., Transfus. Cell Ther. [online]. 2020, vol.42, n.3 [cited 2020-12-02], pp.212-214. Available from: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2531-13792020000300212&lng=en&nrm=iso&gt;. Epub Sep 18, 2020. ISSN 2531-1387. https://doi.org/10.1016/j.htct.2020.06.003.

Study 425 – Pregnant health care workers with Covid in Mexico

Of 11,226 health-care workers with Covid-19 living in Mexico city, 38 (0.34%) were pregnant, compared with 49/23,869 (0.21%) of HCWs without Covid-19 (click here or ciaa1487). Citation: Antonio-Villa NE, Bello-Chavolla OY, Vargas-Vázquez A, Fermín-Martínez CA, Márquez-Salinas A, Bahena-López JP. Health-care workers with COVID-19 living in Mexico City: clinical characterization and related outcomes. Clin Infect Dis. 2020 Sep 28:ciaa1487. doi: 10.1093/cid/ciaa1487. Epub ahead of print. PMID: 32986819; PMCID: PMC7543362.

Study 424 – Screening in Belgium

Of 221 pregnant women tested on admission to the obstetric ward, 10 (4.5%) were positive, of whom 4 had symptoms (click here or [16193997 – Journal of Perinatal Medicine] Testing of patients and coronavirus disease 2019 (COVID-19) infection before scheduled deliveries (1)). The hospital was Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium. The cases may therefore overlap with those in studies 100 and 278, but likely not with those in studies 193 and 217. Citation: Yombi JC, De Greef J, Bernard P, Belkhir L. Testing of patients and coronavirus disease 2019 (COVID-19) infection before scheduled deliveries. J Perinat Med. 2020 Nov 26;48(9):995-996. doi: 10.1515/jpm-2020-0444. PMID: 32990649.

Study 423 – 111 cases from Wuhan, China

31 pregnant women admitted to Renmin Hospital of Wuhan University grid.412632.0 from January 15 to February 23 were compared with 80 non-pregnant women (click here or ofaa294). The cases may overlap with those in studies 6a, 10, 12, 36, 37, 40, 80, 183, 220 and 294. Citation: Biheng Cheng, Tao Jiang, Lu Zhang, Ruheng Hu, Jinhua Tian, Yan Jiang, Bo Huang, Jun Li, Min Wei, Jing Yang, Shengxiang Ren, Gaohua Wang, Clinical Characteristics of Pregnant Women With Coronavirus Disease 2019 in Wuhan, China, Open Forum Infectious Diseases, Volume 7, Issue 8, August 2020, ofaa294, https://doi.org/10.1093/ofid/ofaa294

Study 422 – Two mid-trimester cases from Wuhan, China

Two women contracted Covid-19 in the mid-trimester (click here or No evidence for vertical transmission of SARS CoV 2 in two neonates with mothers infected in the second trimester). The babies were unaffected. They were cared for in Wuhan No.1 Hospital grid.410609.a which appears to be separate from other Wuhan hospitals which have reported cases. Citation: Jing-yi Tang, Wen-qi Song, Hao Xu & Na Wang (2020) No evidence for vertical transmission of SARS-CoV-2 in two neonates with mothers infected in the second trimester, Infectious Diseases, 52:12, 913-916, DOI: 10.1080/23744235.2020.1798499

Study 421 – case report from Lima, Peru

An asymptomatic pregnant woman with SARS-CoV-2 antibodies, but PCR negative, delivered vaginally (click here or en_2304-5132-rgo-66-02-00008). From author affiliations the hospital was Delgado Clinic – AUNA, Lima, Peru, which has not previously reported cases.  Citation: Campodónico Olcese L, Paredes Salas JR, Campodónico Olcese D, Chang Vargas C, Acuña Barrueto L, Marchena Arias J. Management of eutocic delivery in a patient with COVID-19 in Lima, Peru. Rev Peru Ginecol Obstet: 2020;66(2) DOI: https://doi.org/10.31403/rpgo.v66i2251

Study 420 – 65 cases in Colombia

Of 946 pregnant women surveyed, between April 13 and May 18, in seven cities in Colombia, 65 had symptoms of Covid-19, 10 had required hospitalisation and 5 had tested positive. (click here or ijgo.13348). Citation: Parra‐Saavedra, M., Villa‐Villa, I., Pérez‐Olivo, J., Guzman‐Polania, L., Galvis‐Centurion, P., Cumplido‐Romero, Á., Santacruz‐Vargas, D., Rivera‐Moreno, E., Molina‐Giraldo, S., Guillen‐Burgos, H., Navarro, E., Flórez‐Lozano, K., Barrero‐Ortega, A., Sanz‐Cortes, M. and Miranda, J. (2020), Attitudes and collateral psychological effects of COVID‐19 in pregnant women in Colombia. Int J Gynecol Obstet, 151: 203-208. https://doi.org/10.1002/ijgo.13348

Study 419 – 31 cases from Pakistan

From 29th March to 9th May, 31/303  pregnant women tested positive for SARS-CoV-2 on admission in labour, of whom 29 had symptoms (click here or ANN_20_03_17). They were cared for in the Government Maternity Hospital, Gujrat, the Basic Health Unit, Fatehpur, Shaikh Zayed Hospital Lahore and DUHS Hospital Karachi, which have not previously reported cases.Citation: Ullah R, Memon FS, Anjum S. The alarming rate of COVID-19 among pregnant women in Pakistan. Anaesth. pain intensive care 2020;24(4):471-472. DOI: 10.35975/apic.v24i4.1325 

1st December update – studies 406 to 418 added

Study 418 – 86 cases from USA

Of 1,989 pregnant women screened for SARS-CoV-2, 86 (4.3%) tested positive (click here or An initiative to evaluate the safety of maternal bonding in patients with SARS CoV 2 infection). Rooming in, breastfeeding and neonatal infection are reported. The hospital was the University of Maryland School of Medicine, Baltimore. Apart from the single case in study 269 these are the first cases reported from that hospital. Citation: Liviu Cojocaru, Sarah Crimmins, Sripriya Sundararajan, Katherine Goetzinger, Emad Elsamadicy, Allison Lankford, Ozhan M. Turan & Sifa Turan (2020) An initiative to evaluate the safety of maternal bonding in patients with SARS-CoV-2 infection, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1828335. 

Study 417 – 8 pregnant women in ITU, Spain

Among 3,033 patients critically ill with Covid-19 in Vall dHebron University Hospital in Barcelona were eight pregnant women treated in intensive care (click here or 1-s2.0-S0213005X2030272X-main). All eight survived. They probably overlap with those in studies 140, 185 and 413. Citation: Ferrer R, Báguena M, Balcells J, Bañeras J, Biarnes A, de Nadal M, Gracia RM, Martinez J, Nuvials X, Riera J, Roca O, Ruiz-Rodriguez JC. Planning for the assistance of critically ill patients in a Pandemic Situation: The experience of Vall d’Hebron University Hospital. Enferm Infecc Microbiol Clin. 2020 Sep 8:S0213-005X(20)30272-X. English, Spanish. doi: 10.1016/j.eimc.2020.08.007. Epub ahead of print. PMID: 33010961.

Study 416 – Mother & newborn with Covid-19 from Mexico

A woman with severe Covid-19 at term required ventilation, and delivered a baby by Caesarean, who tested positive and had a clinical diagnosis of Covid-19 (click here or PIIS1201971220306846). Both mother and baby recovered. Both were treated at Hospital de Ginecología y Obstetricia, Instituto Materno Infantil del Estado de México, Toluca, which appears to be different from other hospitals reporting cases from that city in study 396, and has therefore probably not been previously reported. Citation: Hinojosa-Velasco A, de Oca PVB, García-Sosa LE, Mendoza-Durán JG, Pérez-Méndez MJ, Dávila-González E, Ramírez-Hernández DG, García-Mena J, Zárate-Segura P, Reyes-Ruiz JM, Bastida-González F. A case report of newborn infant with severe COVID-19 in Mexico: Detection of SARS-CoV-2 in human breast milk and stool. Int J Infect Dis. 2020 Nov;100:21-24. doi: 10.1016/j.ijid.2020.08.055. Epub 2020 Aug 27. PMID: 32860950; PMCID: PMC7449937.

Study 415 -388 pregnancies collected by WAPM

388 singleton pregnancies positive for Covid-19 from 73 centers in 22 countries collected by the World Association of Perinatal Medicine (click here or [16193997 – Journal of Perinatal Medicine] Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19)_ a secondary analysis of the WAPM study on COVID-19). These cases were also reported in studies 278 and 307. The centres are listed but not the number of cases per centre. Citation: Di Mascio D, Sen C, Saccone G, Galindo A, Grünebaum A, Yoshimatsu J, Stanojevic M, Kurjak A, Chervenak F. Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM study on COVID-19. J Perinat Med. 2020 Nov 26;48(9):950-958. doi: 10.1515/jpm-2020-0355. PMID: 32975205.

Study 414 – Low rate of symptomatic disease at birth

17/3,923 (0.43%) of pregnant women admitted to labor and delivery units in Kaiser Permanente Southern California (KPSC) hospitals between April 6 and May 11, who underwent SARSCoV-2 testing were positive (click here or s-0040-1714060). None had symptoms, although one woman developed a headache attributed to COVID-19 3 days postpartum. All babies tested negative. This is the first report from the Kaiser Permanante network. Citation: Fassett MJ, Lurvey LD, Yasumura L, Nguyen M, Colli JJ, Volodarskiy M, Gullett JC, Braun D, Fong A, Trivedi N, Bruxvoort K, Chiu V, Getahun D. Universal SARS-Cov-2 Screening in Women Admitted for Delivery in a Large Managed Care Organization. Am J Perinatol. 2020 Sep;37(11):1110-1114. doi: 10.1055/s-0040-1714060. Epub 2020 Jul 3. PMID: 32620022; PMCID: PMC7516390.

Study 413 – Two cases from Spain

Two women with severe Covid-19 requiring ventilation, one with twins, gave birth prematurely (click here or PIIS1875957220301455). All three babies tested negative and had an uneventful course. They were cared for in Vall d’Hebron University Hospital in Barcelona, so may overlap with studies 140, 185 and 196, as well as other Spanish registry studies. Citation: Fernandez-Garcia C, Montaner-Ramon A, Hernandez-Perez S, Camba-Longueira F, Ribes-Bautista C, Frick MA, Castillo-Salinas F. Severe COVID-19 during pregnancy and the subsequent premature delivery. Pediatr Neonatol. 2020 Sep 19:S1875-9572(20)30145-5. doi: 10.1016/j.pedneo.2020.09.005. Epub ahead of print. PMID: 33039313; PMCID: PMC7501516.

Study 412 – Abnormal bleeding at Caesarean in USA

A woman had abnormal bleeding at Caesarean, and subsequently tested positive for SARS-CoV-2 (click here or s12884-020-03140-2). From author affiliations she was cared for at Icahn School of Medicine at Mount Sinai West, New York, so might be included in studies 86, 119, and 131. Citation: Kinsey, K.E., Ganz, E., Khalil, S. et al. Intraoperative coagulopathy during cesarean section as an unsuspected initial presentation of COVID-19: a case report. BMC Pregnancy Childbirth 20, 481 (2020). https://doi.org/10.1186/s12884-020-03140-2

Study 411 – Eclampsia and Covid-19

A woman with eclampsia and cortical blindness at term who also tested positive for SARS-CoV-2 (click here or s12884-020-03275-2). She recovered. The baby outcome is not reported. She was cared for in the University Complex Hospital of Leon, which has not previously reported cases, but was included in other multicentre reports from Spain. Citation: Garcia Rodriguez A, Marcos Contreras S, Fernandez Manovel SM, Marcos Vidal JM, Diez Buron F, Fernandez Fernandez C, Riveira Gonzalez MDC. SARS-COV-2 infection during pregnancy, a risk factor for eclampsia or neurological manifestations of COVID-19? Case report. BMC Pregnancy Childbirth. 2020 Oct 6;20(1):587. doi: 10.1186/s12884-020-03275-2. PMID: 33023500; PMCID: PMC7538036.

Study 410 – Covid in a pregnant man with cystic fibrosis

A transgender man (genetically female, identifying as male) with cystic fibrosis contracted Covid-19 at 39 weeks gestation (click here or PIIS246804512030050X). The baby tested negative.  From author affiliations the patient was cared for in Sunshine Coast University Hospital, Queensland, Australia which has not previously reported cases. The case is likely to be the same as news report 220 (click here). Citation: Walczak A, Wilks K, Shakhovskoy R, Baird T, Schlebusch S, Taylor C, Reid D, Choong K. COVID-19 in a complex obstetric patient with cystic fibrosis. Infect Dis Health. 2020 Nov;25(4):239-241. doi: 10.1016/j.idh.2020.07.002. Epub 2020 Jul 23. PMID: 32763024; PMCID: PMC7379287.

Study 409 – Triplets from Iran

A woman with IVF triplets contracted Covid-19 and was delivered by Caesarean at 30 weeks (click here or IJN_Volume 11_Issue 3_Pages 120-122). She survived. The triplets all tested negative but two died of complications of prematurity. They were cared for in Arash Hospital, Tehran and appear to be the same triplets as case 5 in study 250. Citation: Farsi Z, Taheriderakhsh N, Bassirnia M, Ahmadi L, Shiva M, Yousefzadegan S. Coronavirus Disease-2019 Infection in Neonates of an Infected Pregnant Mother with Triplets. 2020 Sep: 11(3). DOI: 10.22038/ijn.2020.49218.1856

Study 408 – Post partum cardiomyopathy and Covid-19

A woman had experienced fever, cough, and altered sense of taste and smell a week before giving birth normally March 21(click here or echo.14873). On April 22 she developed cardiomyopathy and tested postive for SARS-CoV-2. She recovered. She was cared for in Luigi Sacco University Hospital, Milan, Italy, but it is not clear if she was included in the various Lombardy series. Citation: De Vita, SIppolito, SCaracciolo, MMBarosi, APeripartum cardiomyopathy in a COVID-19-infected woman: differential diagnosis with acute myocarditis—A case report from a Hub Institution during the COVID-19 outbreak. Echocardiography. 2020371673– 1677https://doi.org/10.1111/echo.14873

Study 407 – 26 cases from Quatar

There were 26 pregnant women with Covid-19 in this series (click here or s12879-020-05511-8). Two women miscarried, there were 10 live births and 14 pregnancies are ongoing. Cared for by Hamad Medical Corporation. Some cases are probably included in study 364. Citation: Omrani, A.S., Almaslamani, M.A., Daghfal, J. et al. The first consecutive 5000 patients with Coronavirus Disease 2019 from Qatar; a nation-wide cohort study. BMC Infect Dis 20, 777 (2020). https://doi.org/10.1186/s12879-020-05511-8

Study 406 – 43 cases from China

These 43 cases from Tongji Hospitalgrid.412793.a Wuhan, China, have surely been reported many times already (click here or pdf). Citation: Wei L, Gao X, Chen S, Zeng W, Wu J, Lin X, Zhang H, Mwamaka Sharifu L, Chen L, Feng L, Wang S. Clinical Characteristics and Outcomes of Childbearing-Age Women With COVID-19 in Wuhan: Retrospective, Single-Center Study. J Med Internet Res. 2020 Aug 24;22(8):e19642. doi: 10.2196/19642. PMID: 32750000; PMCID: PMC7446716.

30th November update – studies 397 to 405 added

Study 405 – 77 placentas from USA

The placental histology of 77 COVID-19 pregnancies are reported (click here or 1-s2.0-S0002937820311947-main). The patients were delivered at NYU Winthrop Hospital, New York so may have been included in studies 61 and 91. Citation: Patberg ET, Adams T, Rekawek P, Vahanian SA, Akerman M, Hernandez A, Rapkiewicz AV, Ragolia L, Sicuranza G, Chavez MR, Vintzileos AM, Khullar P. Coronavirus disease 2019 infection and placental histopathology in women delivering at term. Am J Obstet Gynecol. 2020 Oct 19:S0002-9378(20)31194-7. doi: 10.1016/j.ajog.2020.10.020. Epub ahead of print. PMID: 33091406; PMCID: PMC7571377.

Study 404 – Case report from USA

A woman contracted Covid-19 at 38 weeks (click here or 9796-Article Text-55170-2-10-20200902). She had altered liver enzymes but recovered. The baby was not infected. From author affiliations she was probably cared for in St. John’s Episcopal Hospital, Far Rockaway, New York, which has not previously reported cases. Citation: Nkeih C, Sisti G, Schiattarella A. Elevated transaminases in a COVID-19 positive patient at term of gestation: a case report: Covid19 and pregnancy. Acta Bio Med [Internet]. 2020Sep.7 [cited 2020Nov.30];91(3):e2020002. https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/9796

Study 402 – 9 cases from Nigeria

Nine pregnant women with COVID-19 gave birth at Lagos University Teaching Hospital (click here or ijgo.13436). Eight delivered by caesarean and there was one macerated stillbirth. This is the first series from this hospital although one case might be the same as in study 243. Citation: Banke‐Thomas, A., Makwe, C.C., Balogun, M., Afolabi, B.B., Alex‐Nwangwu, T.A. and Ameh, C.A. (2020), Utilization cost of maternity services for childbirth among pregnant women with coronavirus disease 2019 in Nigeria’s epicenter. Int J Gynecol Obstet. https://doi.org/10.1002/ijgo.13436

Study 401 – six cases from Mexico

Six women with Covid-19 underwent caesarean (click here or 1-s2.0-S2049080120303939-main). Two were admitted to ICU but no mothers or babies died. They were cared for in the General Hospital of Mexico “Dr. Eduardo Liceaga”, Mexico City, so might be included in study 340. Citation: Dra Mariel González-Calatayud, Dr Benito Vargas-Ábrego, Dra Gabriela E. Gutiérrez-Uvalle, Dra Sandra C. López-Romero, Dr Luis Gabriel González-Pérez, Dr José Alberto Carranco-Martínez, Dr Jed Raful-Zacarías-Ezzat, Dr Noé I. Gracida-Mancilla. Observational study of the suspected or confirmed cases of sars COV-2 infection needing emergency surgical intervention during the first months of the pandemic in a third level hospital: Case series, Annals of Medicine and Surgery, Volume 60, 2020, Pages 149-154, ISSN 2049-0801, https://doi.org/10.1016/j.amsu.2020.10.038.

Study 400 – six patients from Italy

Six women with Covid-19 and diabetes are reported (click here or ijgo.13434). They were cared for in Institution Fondazione IRCCS Ca’ Granda, Ospedale Maggiore Policlinico, Milan,and therefore probably included in studies 64, 117, 163, 252, and 312. Citation: D’Ambrosi F, Rossi G, Soldavini CM, Maggi V, Cetera GE, Carbone IF, Di Martino D, Di Maso M, Ferrazzi E. Management of gestational diabetes in women with a concurrent Sars-Cov-2 infection, experience of a single center in Northern Italy. Int J Gynaecol Obstet. 2020 Oct 25. doi: 10.1002/ijgo.13434. Epub ahead of print. PMID: 33099770.

Study 399 – 95 cases from Turkey

95 pregnant women with Covid-19 (click here or jmv.26631). They were cared for at Turkish Ministry of Health Ankara City Hospital between May 11, and August 30, 2020.  They may have been included in studies 203, 223 and 244. Citation: Yazihan, N, Tanacan, A, Erol, SA, et al. Comparison of VEGF‐A values between pregnant women with COVID‐19 and healthy pregnancies and its association with composite adverse outcomes. J Med Virol. 2020; 1‐ 6. https://doi.org/10.1002/jmv.26631

Study 398 – Maternal death & twin pregnancy in Iran

A woman who had conceived twins via IVF, contracted Covid-19 at 28 weeks (click here or 30428-Article Text-131298-6-10-20201031). Mother and both twins died. She was cared for in Shohada-e-Tajrish Hospital, Tehran, which has not previously reported cases, and the clinical details differ from those in studies 23 and 218. Citation: Azizi FarsaniH, BehnazF, TeymourianH, MohseniG.Termination of Pregnancy in a Twin Pregnant Patient with COVID-19.J Cell Mol Anesth.2020;5(3):206-8.

Study 397 – Case Report from China

A woman with Covid-19 gave birth in Suzhou, by Caesarean at 30 weeks (click here or 13274-Article Text-114670-1-10-20201006). The baby was not infected. This may be the same case as study 257b. Citation: Xiaotong Wang, Zhiqiang Zhou, Jianping Zhang, Fengfeng Zhu, Yongyan Tang, Xinghua Shen, A Case of 2019 Novel Coronavirus in a Pregnant Woman With Preterm Delivery, Clinical Infectious Diseases, Volume 71, Issue 15, 1 August 2020, Pages 844–846, https://doi.org/10.1093/cid/ciaa200

29th November update – studies 387 to 394 added

Study 396 – 20 pregnant women with Covid-19 from Mexico

Twenty pregnant or postnatal women with Covid-19 were treated at “Mónica Pretelini Sáenz” Maternal Perinatal Hospital, or “Dr. Nicolás San Juan” General Hospital, both in Toluca (click here or 13274-Article Text-114670-1-10-20201006). Two mothers died, and of the 15 pregnancies which had ended, there were three fetal loses due to: ectopic pregnancy, fetal death at 16 weeks of pregnancy and a postnatal death from prematurity complications. Neither of these hospitals has previously reported cases, although the maternal deaths may have been included in studies 66, 271 and 340Citation: Meneses Calderón J, Figueroa Flores M del R, Paniagua Coria L, Briones Garduño JC, Meneses Figueroa J, Vargas Contretas MJ, de la Cruz Ávila L, Díaz Meza S, Ramírez Chacón R, Padmanabhan S, Mendieta Zerón H (2020) Nitazoxanide against COVID-19 in three explorative scenarios. J Infect Dev Ctries 14:982-986. doi: 10.3855/jidc.13274

Study 395 – 48 cases from China

Maternal and neonatal details reported (click here or 10-1055-s-0040-1716505). The babies were cared for in Tongji Hospital grid.412793.a and HuangShi [?Huazhong] Maternal and Child Healthcare Hospital grid.412793.a, Wuhan, from January 17 to March 4, 2020 so the pregnancies have been reported before. Citation: Liu W, Cheng H, Wang J, et al. Clinical Analysis of Neonates Born to Mothers with or without COVID-19: A Retrospective Analysis of 48 Cases from Two Neonatal Intensive Care Units in Hubei Province. Am J Perinatol. 2020;37(13):1317-1323. doi:10.1055/s-0040-1716505

Study 394 – Infarction of a pituitary tumour and Covid-19 in pregnancy in USA

A woman with visual disturbance at 38 weeks tested positive for SARS-CoV-2 (click here or Chan2020_Article_PituitaryApoplexyAssociatedWit). She delivered vaginally and the baby tested negative. Two weeks later a presumed infarcted pituitary tumour was removed. From author affiliations she was cared for at Cedars-Sinai Medical Center, Los Angeles, and therefore might be included in study 121. Citation: Chan, J.L., Gregory, K.D., Smithson, S.S. et al. Pituitary apoplexy associated with acute COVID-19 infection and pregnancy. Pituitary 23, 716–720 (2020). https://doi.org/10.1007/s11102-020-01080-w

Study 393 – zero cases in pregnancy in a hospital in Slovenia

None of 202 pregnant women tested for SARS-CoV-2 in the Ljubljana Maternity Hospital between March 15 and May 16, 2020 were positive (click here or full text not available). Citation: Šterbenc, A., Premru Sršen, T., Lučovnik, M., Vidmar Šimic, M., Steblovnik, L., Fabjan Vodušek, V., Druškovič, M., Kavšek, G., Poljak, M., & Trojner Bregar, A. (2020). Usefulness of COVID-19 screen-and-test approach in pregnant women: an experience from a country with low COVID-19 burden, Journal of Perinatal Medicine (published online ahead of print 2020), 000010151520200368. doi: https://doi.org/10.1515/jpm-2020-0368

Study 392 – two cases from USA

Two babies born to women with moderately severe Covid-19 are reported (click here or 10-1055-s-0040-1715180). From author affiliations the patients were cared for at Rutgers University, Robert Wood Johnson Medical School, New Brunswick, New Jersey. The mothers may therefore have been included in studies 86 and 285. Citation: Reddy A, Engelhardt K, Jain D. Air Leak Syndrome in Two Very Preterm Infants Born to Mothers with Coronavirus Disease 2019: An Association or a Coincidence?. AJP Rep. 2020;10(3):e266-e269. doi:10.1055/s-0040-1715180

Study 391 – 23 cases from USA

Of 23 pregnant women who tested positive for SARS-CoV-2, 13 had symptoms but none severe disease (click here or Dhuyvetter2020_Article_CoronavirusDisease2019InPregna). They were cared for at John H Stroger Hospital in Chicago, Illinois which has not previously reported cases. Citation: Dhuyvetter, A., Cejtin, H.E., Adam, M. et al. Coronavirus Disease 2019 in Pregnancy: The Experience at an Urban Safety Net Hospital. J Community Health (2020). https://doi.org/10.1007/s10900-020-00940-7

Study 390 – 248 infants from Spain

Breastfeeding rates among 242 mothers with Covid-19 and 248 live newborn infants (click here or PIIS0301211520306400). The infants were born in 15 Spanish hospitals, who were members of the Neo-COVID-19 research group, between 13 March and 31 May, and therefore probably overlap with those in studies 264b and 366. Citation: del Río R, Dip Pérez E, Marín Gabriel MÁ; the Neo-COVID-19 Research Group. Multi-centre study showed reduced compliance with the World Health Organization recommendations on exclusive breastfeeding during COVID-19. Acta Paediatr. 2020;00:1–2. https://doi.org/10.1111/apa.15642

Study 389 – Forceps birth in the ITU in USA

A woman with severe Covid-19 who had already required 5 days ventilation was induced and delivered vaginally by forceps at 33 weeks in the ITU (click here or Induction_of_Labor_in_an_Intubated_Patient_With.15). The perineum was intact. The baby tested negative. The mother required a further 4 days ventilation but recovered. From author affiliations she was cared for at Legacy Salmon Creek Hospital, Vancouver, Washington State, which has not previosly reported cases. Citation: Slayton-Milam, Suzanne MD; Sheffels, Samantha BS; Chan, Dominic PharmD, BCPS (AQ-ID); Alkinj, Bashar MD Induction of Labor in an Intubated Patient With Coronavirus Disease 2019 (COVID-19), Obstetrics & Gynecology: November 2020 – Volume 136 – Issue 5 – p 962-964 doi: 10.1097/AOG.0000000000004044

Study 388 – case report from USA

A woman with severe Covid-19 at 22 weeks (click here or Tocilizumab_and_Remdesivir_in_a_Pregnant_Patient.25). She recovered and the pregnancy is ongoing. From author affiliations she was cared for at Cedars Sinai Medical Center, Los Angeles, California, and therefore might be included in study 121. Citation: Naqvi, Mariam MD; Zakowski, Phillip MD; Glucksman, Lindsey MD; Smithson, Sarah DO, MS; Burwick, Richard M. MD, MPH Tocilizumab and Remdesivir in a Pregnant Patient With Coronavirus Disease 2019 (COVID-19), Obstetrics & Gynecology: November 2020 – Volume 136 – Issue 5 – p 1025-1029 doi: 10.1097/AOG.0000000000004050

Study 387 – 22 cases from USA

Outpatient care of 22 pregnant women with Covid-19 (click here or main (5)). They were cared for at Beth Israel Deaconess Medical Center, Massachusetts, so may have been included in studies 129 and 231. Citation: Reforma LG, Duffy C, Collier AY, et al. A multidisciplinary telemedicine model for management of coronavirus disease 2019 (COVID-19) in obstetrical patients. Am J Obstet Gynecol MFM. 2020;2(4):100180. doi:10.1016/j.ajogmf.2020.100180

28th November update – studies 379 to 386 added

Study 386 – Case from Greece

A patient with mild Covid-19 at term gave birth by Caesarean (click here or JAnaesthClinPharmacol365121-6656644_182926). The authors state this was the first case in this country. From their affiliations the hospital was “Attikon” University Hospital, Athens. Citation: Batistaki C, Galarioti V, Vasiliadou S, Soulioti E, Kostopanagiotou G, Matsota P. Lessons learned from first case of Cesarean delivery in a COVID-19 positive parturient in Greek region. J Anaesthesiol Clin Pharmacol. 2020;36(Suppl 1):S121-S124. doi:10.4103/joacp.JOACP_157_20

Study 385 – Case from India

A pregnant woman had mild Covid-19 at 37 weeks (click here or JAnaesthClinPharmacol36577-6694834_183548). She was delivered by Caesarean under spinal anaesthesia. The baby tested negative. From author affiliations the hospital was Gian Sagar Medical College and Hospital, Banur, Patiala. Citation: Bajwa SJS, Gupta R, Wahi A, Goraya SPS. Exploring the unknown territories in the new normal world of COVID. J Anaesthesiol Clin Pharmacol. 2020;36(Suppl 1):S77-S80. doi:10.4103/joacp.JOACP_350_20

Study 384 – Seroconversion among maternity workers in London

In two London hospitals 29/200 (15%) of obstetric healthcare professionals seroconverted between 11 May 2020 and 5 June 2020 (click here or anae.15229). From author affiliations the hospitals were probably University College London Hospitals NHS Foundation Trust, and Northwick Park Hospital. Citation: Bampoe, S., Lucas, D.N., Neall, G., Sceales, P., Aggarwal, R., Caulfield, K., Siassakos, D. and Odor, P.M. (2020), A cross‐sectional study of immune seroconversion to SARS‐CoV‐2 in frontline maternity health professionals. Anaesthesia, 75: 1614-1619. https://doi.org/10.1111/anae.15229

Study 383 – Follow up of 138 cases from China

This important study reports three month follow-up of 72/138 pregnant women with Covid-19 collected by the National Epidemic Reporting System (NERS) in China (click here or s12916-020-01825-1). All 13 first trimester cases were aborted. In supplementary table 1 (click here or 12916_2020_1825_MOESM1_ESM) it appears that one of the 138 original mothers died; the first report of a maternal death from Covid-19 in China. The cases overlap with those in study 55 and other Chinese reports. Citation: Wang, Y., Chen, L., Wu, T. et al. Impact of Covid-19 in pregnancy on mother’s psychological status and infant’s neurobehavioral development: a longitudinal cohort study in China. BMC Med18, 347 (2020). https://doi.org/10.1186/s12916-020-01825-1

Study 382 – 64 cases from Turkey

Of 64 pregnant women with suspected Covid-19, 33 tested positive (click here or PCR positivity and D-dimer levels in pregnant women with COVID-19). Limited clinical information is presented, but one woman underwent thoracotomy. From author affiliation they were cared for in Kocaeli Derince Training and Research Hospital, Kocaeli, so some may have been included in study 244. Citation: K. Uzel, I. Lakhno. PCR positivity and D-dimer levels in pregnant women with COVID-19. Clin. Exp. Obstet. Gynecol. - ISSN: 0390-6663 XLVII, n. 5, 2020. doi: 10.31083/j.ceog.2020.05.2229

Study 381 – 111 patients with suspected COVID-19 in Spain

In this paper 68 pregnant women who tested positive were compared with 43 who tested negative (click here or jcm-09-03552-v2). The negative group included nine women with both symptoms and radiological findings of pneumonia, one of whom later developed anti SARS-CoV-2 antibodies. The women were cared for in University Hospital Gregorio Marañón, Madrid. They probably overlap with those reported in study 151 and possibly 196. Citation: Cuñarro-López, Y.; Cano-Valderrama, Ó.; Pintado-Recarte, P.; Cueto-Hernández, I.; González-Garzón, B.; García-Tizón, S.; Bujan, J.; Asúnsolo, Á.; Ortega, M.A.; De León-Luis, J.A. Maternal and Perinatal Outcomes in Patients with Suspected COVID-19 and Their Relationship with a Negative RT-PCR Result. J. Clin. Med. 2020, 9, 3552.

Study 380 – 66 cases from Pakistan

66 women who tested positive for SARS-CoV-2 in pregnancy between 27th April and 16th June 2020, were mostly asymptomatic (click here or Bulletin_pdf). No babies were infected. From author affililiations they were cared for at the Indus Hospital, Karachi, which has not previously reported cases. These may be the first reported cases from this country. Citation: Khan M.A., Kumar V., Ali S.R. Vertical Transmission of Novel Coronavirus (COVID-19) from Mother to Newborn: Experience from a Maternity Unit, The Indus Hospital, Karachi. Journal of the College of Physicians and Surgeons–Pakistan : JCPSP. 30 (10) (pp 136), 2020. Date of Publication: 01 Oct 2020.

Study 379 – 34 cases from China

These 34 cases (click here or ofaa283) cared for in Union Hospital Wuhan (grid.412839.5) between January 15 & March 15, 2020, likely overlap with those in  studies 2a, 2b, 2c, 5*, and 6). Citation: Xu S, Shao F, Bao B, et al. Clinical Manifestation and Neonatal Outcomes of Pregnant Patients With Coronavirus Disease 2019 Pneumonia in Wuhan, China. Open Forum Infect Dis. 2020;7(7):ofaa283. Published 2020 Jul 5. doi:10.1093/ofid/ofaa283

27th November update – studies 373 to 378 added

Study 378 – Zero pregnancy cases in one prefecture, Japan

805 pregnant women (half of all women giving birth in the region) were tested for SARS-CoV-2 in Fukui prefecture, Japan between April 24 to July 25, 2020 (click here or jog.14567). All tested negative, and later checking against case notifications of COVID‐19, revealed no missed cases. Fukui had a SARS-CoV-2 prevalence of 16.5/100.000 during this period. Citation: Orisaka, M., Kawamura, H. and Yoshida, Y. (2020), COVID‐19 testing of pregnant women in Japan. J. Obstet. Gynaecol. Res.. https://doi.org/10.1111/jog.14567

Study 377 – Co-infection with rhinovirus & SARS-CoV-2 in pregnancy

A woman was infected with both SARS-CoV-2 and Rhinovirus/Enterovirus at 31 weeks gestation (click here or 21928959 – Case Reports in Perinatal Medicine] A case report of co-infection with rhinovirus and SARS-CoV-2 in pregnancy). She had mild symptoms but recovered and the pregnancy is ongoing. The authors are affiliatated with Renaissance School of Medicine Stony Brook University, Stony Brook, New York, USA, which has not previously reported cases. Citation: Heiselman, C. J., Iovino, N., & Herrera, K. M. (2020). A case report of co-infection with rhinovirus and SARS-CoV-2 in pregnancy, Case Reports in Perinatal Medicine, 9(1), 20200028. doi: https://doi.org/10.1515/crpm-2020-0028

Study 376 – Infected baby from USA

A woman contracted Covid-19 at 36 weeks and was delivered by Caesarean (click here or piaa109). The baby was asymptomatic but tested positive. The baby was born at Presbyterian Brooklyn Methodist Hospital in New York and therefore may be included in study 230. Citation: Ihab Alamar, Mohammad H Abu-Arja, Taryn Heyman, Drucilla J Roberts, Niyati Desai, Pramod Narula, Beata Dygulska, A Possible Case of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in a Newborn With Positive Placental In Situ Hybridization of SARS-CoV-2 RNA, Journal of the Pediatric Infectious Diseases Society, Volume 9, Issue 5, November 2020, Pages 636–639, https://doi.org/10.1093/jpids/piaa109

Study 375 – 50 cases from Iran

Of 50 pregnant women hospitalised with Covid-19 in Hamadan (alt. spelling Hamedan) Province, 2 mothers died, 7 babies were infected and 26 women remain undelivered (click here or jrhs-20-e00488). The recruitment period was January 6, 2020 to June 21, 2020. The hospitals are unnamed and cannot be guessed at from author affliliations. Hamadan province is remote from Tehran, Ilam, Tabriz, and Sari from which most Iranian reports of maternal disease have come. However, study 250 included some infected babies from Hamadan province, and the two maternal deaths may have been included in studies 23 and 67. Citation: Sattari M, Bashirian S, Masoumi SZ, Shayan A, Jenabi E, Ghelichkhani S, Ali Shirzadeh A, Jalili E, Alimohammadi S. Evaluating Clinical Course and Risk Factors of Infection and Demographic Characteristics of Pregnant Women with COVID-19 in Hamadan Province, West of Iran. J Res Health Sci. 2020; 20(3): e00488.

Study 374 – 44 advice calls to a teratology service in Italy

This report describes 44 advice calls to a teratology service in Bergamo in Lombardy concerning drug prescription to 16 pregnant or lactating women with suspected, and 28 with confirmed, Covid-19 (click here or [16193997 – Journal of Perinatal Medicine] Medications prescriptions in COVID-19 pregnant and lactating women_ the Bergamo Teratology Information Service experience during COVID-19 outbreak in Italy). Citation: Giampreti, A., Eleftheriou, G., Gallo, M., Butera, R., Contessa, G., Faraoni, L., Sangiovanni, A., Negri, G., Falchi, G., & Bacis, G. (2020). Medications prescriptions in COVID-19 pregnant and lactating women: the Bergamo Teratology Information Service experience during COVID-19 outbreak in Italy, Journal of Perinatal Medicine, 48(9), 1001-1007. doi: https://doi.org/10.1515/jpm-2020-0339

Study 373 – Case report from the Netherlands

A woman contracted severe Covid-19 at 23 weeks requiring prolonged ventilation and Caesarean delivery at 28 weeks (click here or main (2)). The mother survived. The baby suffered complications of prematurity but was not infected and survived. From author affiliations she was cared for at Leiden University Medical Center. Apart from NethOSS reports, the case has not been previously reported. The centre and clinical features differ from the case in study 263. Citation: du Fossé NA, Bronsgeest K, Arbous MS, et al. Detailed immune monitoring of a pregnant woman with critical Covid-19 [published online ahead of print, 2020 Oct 29]. J Reprod Immunol. 2020;143:103243. doi:10.1016/j.jri.2020.103243

26th November update – studies 368 to 372 added

Study 372 – A case of thyroiditis following post-partum Covid-19 in Japan

A woman contracted Covid-19, 103 days after giving birth, and 33 days later was diagnosed with thyroiditis (click here or advpub_EJ20-0553). From author affililiations the thyroiditis was treated at Wakayama Medical University, Wakayama. Citation: Mizuno S, Inaba H, Kobayashi KI, Kubo K, Ito S, Hirobata T, Inoue G, Akamizu T, Komiya N. A case of postpartum thyroiditis following SARS-CoV-2 infection. Endocr J. 2020 Nov 12. doi: 10.1507/endocrj.EJ20-0553. Epub ahead of print. PMID: 33177251.

Study 371 – 40 cases in USA

Of 40 pregnant women with SARS-CoV-2 cared for in the Nuvance healthcare system, 3/4 had symptoms and 25 delivered (click here or full text not accessed). Of 20 neonates tested for SARS-CoV-2 all were negative. Nuvance maternity hospitals include Vassar Brothers, and Norwalk hospitals, in New York State and Connecticut, neither of which have previously reported cases. Citation: Ogamba, I., Kliss, A., Rainville, N., Chuang, L., Panarelli, E., Petrini, J., & Zilberman, D. (2020). Initial review of pregnancy and neonatal outcomes of pregnant women with COVID-19 infection, Journal of Perinatal Medicine (published online ahead of print 2020), 000010151520200446. doi: https://doi.org/10.1515/jpm-2020-0446

Study 370 – A postnatal woman treated with ECMO in Japan

A woman with Covid-19 at 36 weeks gestation was delivered by Caesarean (click here or amjcaserep-21-e927521). The baby tested negative but the mother’s condition deteriorated, necessitating ventilation and later ECMO. She recovered. She was delivered in an unnamed general hospital in Tokyo, and from author affiliations the postnatal intensive care probably took place at Tokyo Medical and Dental University Hospital, Tokyo. These, and the clinical features, suggest she has not been included in previous series from Japan. Citation: Takayama W, Endo A, Yoshii J, et al. Severe COVID-19 Pneumonia in a 30-Year-Old Woman in the 36th Week of Pregnancy Treated with Postpartum Extracorporeal Membrane Oxygenation. Am J Case Rep. 2020;21:e927521. Published 2020 Oct 28. doi:10.12659/AJCR.927521

Study 369 – 3 pregnant women with Covid-19 & malaria, and one with dengue from India

All four survived although one of the women with malaria experienced an intrauterine fetal death at 24 weeks (click here or ijgo.13415). They were cared for in Nair hospital in Mumbai, so may have been included in studies 225 & 283. Citation: Mahajan, N.N., Kesarwani, S.N., Shinde, S.S., Nayak, A., Modi, D.N., Mahale, S.D. and Gajbhiye, R.K. (2020), Co‐infection of malaria and dengue in pregnant women with SARS‐CoV‐2. Int. J. Gynecol. Obstet., 151: 459-462. https://doi.org/10.1002/ijgo.13415

Study 368 – Covid-19 in a pregnant renal transplant recipient

A woman who was 30 weeks pregnant with a renal transplant contracted Covid-19 (click here or 40620_2020_Article_897). She recovered and gave birth normally at term. The baby was not tested. From author affiliations she was probably cared for at Queen Charlottes & Chelsea Hospital in London, UK, which has not previously reported cases.  Citation: Gleeson S, Noori M, Lightstone L, Webster P. Lesson for the clinical nephrologist: Kidney transplant, COVID-19 and pregnancy [published online ahead of print, 2020 Nov 12]. J Nephrol. 2020;1-3. doi:10.1007/s40620-020-00897-9

25 November update – studies 362 to 367 added

Study 367 – Two cases from Italy

Santo Stefano Hospital in Prato, in Tuscany treated two cases of Covid-19 in pregnancy (click here or Cavaliere) and has not previously reported cases. Citation: A. F. Cavaliere, P. L. Vasarri, E. Scatena, A. Vidiri, M. S. Santicchia, I. Bordoni Vicini, M. Gardelli, F. Bressan, D. Matarrese, F. Perelli. SARS-CoV2 containment during pregnancy: single Center experience and the unique Chinese reality in Prato. Italian Journal of Gynæcology & Obstetrics September 2020 – Vol.32 – N. 3 – Quarterly – ISSN 2385 – 0868 

Study 366 – 403 cases from Spain

These 403 cases of Covid-19 in pregnancy were divided into 231 with early cord clamping and 172 with delayed (click here or 1471-0528.16597). Two and three infants respectively tested positive. The cases were selected from the Spanish Registry of COVID-19 which collects cases from 100 Spanish hospitals. Citation: Mejía Jiménez, I., Salvador López, R., García Rosas, E., de la Torre, I.R., Montes García, J., de la Cruz Conty, M.L., Martínez Pérez, O. and (2020), Umbilical cord clamping and skin‐to‐skin contact in deliveries from women positive for SARS‐CoV‐2: a prospective observational study. BJOG: An International Journal of Obstetrics & Gynaecology. Accepted Author Manuscript. https://doi.org/10.1111/1471-0528.16597

Study 365 – 3 cases from UK

Three pregnant women were included in this series from Southampton General Hospital, UK (click here or 1-s2.0-S0163445320306381-main). No further details are given. Citation: N.J. Brendish, S. Poole, V.V. Naidu et al., Clinical characteristics, symptoms and outcomes of 1054 adults presenting to hospital with suspected COVID-19: A comparison of patients with and without SARS-CoV-2 infection, Journal of Infection, https://doi.org/10.1016/j.jinf.2020.09.033

Study 364 – 678 cases from Qatar

There were 678 pregnant women testing positive for SARS-CoV-2 in this preprint (click here or main (1)). These are the first pregnant cases reported from Quatar. Citation: Ehab Hamed, Ahmed Sameer Alnuaimi, Mohamed Ahmed Syed, Mohamed Abd Elhamid , Saad Thamer Sedeeq , Bayan Alemrayat , Amina Ali Mohamed Muktar, AlAnoud Saleh AlFehaidi , Hamda Abdulla A/Qotba, Clinical characteristics of 51815 patients presenting with positive and negative SARS-CoV-2 swab results in primary health care settings, Journal of Infection (2020), doi: https://doi.org/10.1016/j.jinf.2020.11.014. Final published version(click here or PIIS016344532030709X)

Study 363 – A maternal death from Birmingham UK

A woman with Covid-19 in pregnancy was ventilated and transferred elsewhere for ECMO but died (click here). Full text not available, so it is not yet clear if the case has been reported elsewhere. Citation: Stout A, Crichton R, Tahmasebi F. Maternal death secondary to COVID-19 infection: A case report and review of the literature. Obstetric Medicine. November 2020. doi:10.1177/1753495X20970816

Study 362 – Case report from USA

A case of severe COVID-19 pneumonia in a periviable pregnancy treated with concurrent combination of remdesivir, corticosteroids, and convalescent plasma therapy, leading to rapid maternal pulmonary improvement (click here or ). Full text not yet obtained. From author affiliation cared for at St. Mary’s Hospital-St. Louis, Missouri, which has not previously reported cases. Citation: Lam H., Lacasse A.  Combination of remdesivir, corticosteroid, and convalescent plasma for severe COVID-19 in periviable pregnancy. Infectious Diseases in Clinical Practice. 28 (6) (pp e21-e23), 2020. Date of Publication: 01 Nov 2020.

24th November update – studies 359 to 361 added

Study 361 – 252 cases from Texas

252 pregnant women who tested positive for SARS-CoV-2 were compared with 3,122 who tested negative (click here or adhikari_2020_oi_200933_1605126584.8159). There was no difference in a primary composite outcome of birth <37 weeks, severe pre-eclampsia, or cesarean for abnormal fetal heart rate. There were no maternal deaths in either group. No babies died in the SARS-CoV-2 group. Women were cared for at Parkland Health and Hospital System, Dallas. Citation: Adhikari EH, Moreno W, Zofkie AC, et al. Pregnancy Outcomes Among Women With and Without Severe Acute Respiratory Syndrome Coronavirus 2 Infection. JAMA Netw Open. 2020;3(11):e2029256. doi:10.1001/jamanetworkopen.2020.29256

Study 360 – 21 cases from Israel

21 women with Covid-19 all gave birth to healthy babies, one of whom tested positive (click here or Lopian PedNeo). They were cared for in Mayanei Hayeshua Medical Center in Bnei Brak, between March 23, 2020, and May 8, 2020. This centre has not previously reported cases. Citation: Lopian M et al., Safety of vaginal delivery in women infected with COVID-19, Pediatrics and Neonatology, https://doi.org/10.1016/j.pedneo.2020.10.010

Study 359 – 39 severe cases from US 

In this case control study, 39 pregnant women with severe or critical Covid-19 were compared with 94 non-pregnant women (click here or DeBolt AJOG). They were cared for in four academic medical centers in New York and one in Philadelphia. Some or all of the pregnant women have probably been previously reported in studies 85, 86, 91, 98, 152, 160, 175 and 350. Citation: DeBolt CA, Bianco A, Limaye MA, Silverstein J, Penfield CA, Roman AS, Rosenberg HM, Ferrara L, Lambert C, Khoury R, Bernstein PS, Burd J, Berghella V, Kaplowitz E, Overbey JR, Stone J, Pregnant women with severe or critical COVID-19 have increased composite morbidity compared to non-pregnant matched controls, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.11.022.

23rd November update – studies 357 and 358 added

Study 358 – A case from Brazil

A woman contracted severe Covid-19 at 27 weeks gestation, the fetus died in utero, was delivered by Caesarean section and tested positive (click here). The mother required ventilation but recovered. From author affiliations she was cared for in Hospital de Clínicas da Universidade Federal do Paraná, Parana. Citation: Stonoga ETS, Lanzoni LA, Rebutini PZ, Olveira ALP, Chiste JA, Fugaça CA, et al. Intrauterine transmission of SARS-CoV-2. Emerg Infect Dis. 2021 Feb [date cited]. https://doi.org/10.3201/eid2702.203824

Study 357 – A case from China

Among 67 cases of COVID-19 in Wenzhou, one was in a pregnant woman (click here or s12879-020-05528-z). No details are given of her, but all patients survived. They were cared for in Ruian People’s Hospital grid.452885.6 which has not previously reported cases. Citation: Hong, L., Ye, E., Sun, G. et al. Clinical and radiographic characteristics, management and short-term outcomes of patients with COVID-19 in Wenzhou, China. BMC Infect Dis 20, 841 (2020). https://doi.org/10.1186/s12879-020-05528-z

22nd November update – studies 353 to 356 added

Study 356 – 15 women from Italy

Among 15 pregnant women with SARS-CoV-2 none delivered infected infants (click here or fped-08-565522). They were cared for at City Hospital in Piacenza from late February through May 15, 2020. Although just outside Lombardy they have probably been reported in studies 32, 64 and 117. Citation: Biasucci G, Cannalire G, Raymond A, Capra ME, Benenati B, Vadacca G, Schiavo R, Pavesi C, Bonini R. Safe Perinatal Management of Neonates Born to SARS-CoV-2 Positive Mothers at the Epicenter of the Italian Epidemic. Front Pediatr. 2020 Oct 29;8:565522. doi: 10.3389/fped.2020.565522. PMID: 33194893; PMCID: PMC7658585.

Study 355 – Two cases from Northwestern China

Among 617 COVID-19 patients in this region, over 1,000km from Wuhan, two were pregnant, and one gave birth to a healthy baby at term. The outcome of the other was not reported. The exact location of neither was reported. Citation: Zhu J, Zhang Q, Jia C, et al. Epidemiological Characteristics and Clinical Outcomes of Coronavirus Disease Patients in Northwest China: High-Volume Research From Low Population Density Regions. Front Med (Lausanne). 2020;7:564250. Published 2020 Oct 30. doi:10.3389/fmed.2020.564250

Study 354 –  First trimester case from France

A woman with an ivf pregnancy contracted Covid-19 at 7 weeks (click here or s12879-020-05551-0). Prior to the diagnosis she had been treated with estradiol, progesterone, corticosteroids, chloroquine, aspirin & heparin. Liver enzymes were raised. She recovered. The pregnancy was ongoing at the time of the report. From author affiliations she was cared for at Hôpital Privé de Parly 2, Le Chesnay, Paris. Citation: Lamazou, F., Oger, P., Dieli-crimi, R. et al. COVID-19 infection in first trimester of pregnancy marked by a liver cytolysis in a woman previously treated by hydroxychloroquine for repeated implantation failure: a case report. BMC Infect Dis 20, 845 (2020). https://doi.org/10.1186/s12879-020-05551-0

Study 353 – Anaphylaxis after convalescent plasma therapy

A woman with Covid-19 at 31 weeks gestation experienced an anaphylactic reaction after treatment with convalescent plasma (click here or 1-s2.0-S0012369220330798-main). She required delivery. Neither mode of birth nor outcome for mother or baby was reported. The hospital was unnamed and no author affiliations are given. Citation: MARGARET MALLARI SREEJA SOMPALLI SHAISTA NOORMOHAMMAD ISHITA MALIK AND SIVASHANKAR SIVARAMAN. ANAPHYLACTIC SHOCK IN A PREGNANT PATIENT WITH COVID-19 IN THE SETTING OF CONVALESCENT PLASMA TRANSFUSION. CHEST, Volume 158, Issue 4, A959

15 November update – study 352 added

Study 352 – infected stillbirth in Portugal

An asymptomatic woman gave birth to a hydropic stillborn fetus at 34 weeks (click here or PIIS0301211520307533). Both mother and fetus tested positive for SARS-CoV-2. From author affiliations she was cared for at Hospital Prof. Doutor Fernando Fonseca, Amadora, which has not previously reported cases. Citation: Rodrigues ML, Gasparinho G, Sepulveda F, Matos T, Signs suggestive of congenital SARS-CoV-2 infection with intrauterine fetal death: a case report, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.11.042

11 November update – study 351 added

Study 351 – SARS-CoV-2 seroprevalence in antenatal samples in Australia

This anonymised seroprevalence study on samples collected between April & June 2020 in Sydney, included 560 samples from women undergoing antenatal screening. 0.79% were positive for SARS-CoV-2 IgG (click here or Gidding mja20.01971 – 11 November 2020_0). Citation: Heather F Gidding, Dorothy A Machalek, Alexandra J Hendry, Helen E Quinn, Kaitlyn Vette, Frank H Beard, Hannah Shilling, Rena Hirani, Iain B Gosbell, David O Irving, Linda Hueston, Marnie Downes, John B Carlin, Matthew NV O’Sullivan, Dominic E Dwyer, John M Kaldor and Kristine Macartney. Seroprevalence of SARS-CoV-2-specific antibodies in Sydney, Australia following the first epidemic wave in 2020 Med J Aust. Published online: 11 November 2020

10 November update – studies 349 and 350 added

Study 350 – 8 pregnant women detected by screening in USA

Of 318 pregnant women screened between April 13th & 26th, 2020, eight tested positive for Sars-CoV-2 (click here or Bender AJOG MFM main). The women were screened in the Hospital of the University of Pennsylvania and Pennsylvania Hospital, and may overlap with some reported in studies 65, 86, 175, and 202Citation: Bender WR, Hirshberg A, Coutifaris P, et al. Universal testing for severe acute respiratory syndrome coronavirus 2 in 2 Philadelphia hospitals: carrier prevalence and symptom development over 2 weeks. Am J Obstet Gynecol MFM 2020;2:100226.
https://doi.org/10.1016/j.ajogmf.2020.100226

Study 349 – 66 babies with neonatal SARS-CoV-2 infection in UK

Of 66 neonates with confirmed SARS-CoV-2 infection, 28 (42%) had severe disease,16 (24%) were born preterm and one died of an unrelated cause (click here or Gale Lancet PIIS2352464220303424). However, only two babies (3%) were considered to have possible vertically acquired infection (SARS-CoV-2-positive sample within 12 h of birth where the mother was also positive). Citation: Gale, Chris et al. Characteristics and outcomes of neonatal SARS-CoV-2 infection in the UK: a prospective national cohort study using active surveillance. The Lancet Child & Adolescent Health, Volume 0, Issue 0 DOI: https://doi.org/10.1016/S2352-4642(20)30342-4&nbsp; [important]

9th November update – study 342 (update of 203) and 343 to 348 added

Study 348 – 33 patients from USA

Of 33 women with Covid-19, two required ventilation and one died (click here or Curi AJOG MFM). The were two intrauterine fetal deaths. Patients were cared for at Lincoln Hospital Medical and Mental Health Center, South Bronx, which has not previously reported cases. Citation: Berenice Curi, Alexander Sabre, Israel Benjamin, Lisa Serventi, Dilfuza Nuritdinova. Coronavirus infection in a high-risk obstetrical population of the South Bronx, New York, American Journal of Obstetrics & Gynecology MFM, Volume 2, Issue 4, Supplement, 2020, 100203, ISSN 2589-9333, https://doi.org/10.1016/j.ajogmf.2020.100203. (http://www.sciencedirect.com/science/article/pii/S2589933320301725)

Study 347 – Case report from Monterrey, Mexico

A woman contracted severe Covid-19 at 27 weeks (click here or ijgo.13467). She required four days ventilation and was also treated with enoxaparin, azithromycin, ceftaroline, lopinavir/ritonavir, methylprednisolone and convalescent plasma. She recovered and delivered a growth restricted baby (birth weight not reported) at 39 weeks. The hospital was San José Tec Salud which has not previously reported cases. However, she may be included in study 340. Citation: Magallanes‐Garza, G.I., Valdez‐Alatorre, C., Dávila‐González, D., Martínez‐Reséndez, M.F., Sánchez‐Salazar, S.S., Castilleja‐Leal, F. and Cardona‐Huerta, S. (2020), Rapid improvement of a critically ill obstetric patient with SARS‐CoV‐2 infection after administration of convalescent plasma. International Journal of Gynecology & Obstetrics. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13467

Study 346 – 4 cases from France

Two women with Covid-19 delivered infected babies (click here or hascoet fped-08-568979). Two others delivered uninfected babies. From author affiliations they were likely cared for at Maternite Regionale CHRU Nancy, and therefore probably included in study 150Citation: Hascoët Jean-Michel, Jellimann Jean-Marc, Hartard Cedric, Wittwer Apolline, Jeulin Hélène, Franck Patricia, Morel Olivier. Case Series of COVID-19 Asymptomatic Newborns With Possible Intrapartum Transmission of SARS-CoV-2. Frontiers in Pediatrics VOLUME=8. 2020. P 632. URL=https://www.frontiersin.org/article/10.3389/fped.2020.568979. DOI=10.3389/fped.2020.568979

Study 345 – 15 maternal deaths from Covid-19 in Iran

Of 32 women who tested positive at Firoozgar General Hospital, Tehran, 15 died (click here or Moghadam ijgo.13461). Although this hospital has not previously reported cases, overlap with cases in studies 23, 67 & 218 cannot be excluded. Citation: Moghadam, S.A., Dini, P., Nassiri, S., Motavaselian, M., Hajibaba, M. and Sohrabi, M. (2020), Clinical features of pregnant women in Iran who died due to COVID‐19. Int J Gynecol Obstet. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13461

Study 344 – Case report from USA

A woman with Covid-10 was delivered by Caesarean on 3 April (click here or 2050313×20945536). She and the baby were fine. The patient was treated in Lehigh Valley Hospital, Stroudsburg, Pennsylvania, which has not previously reported cases.  Citation: Krupa Daniel, Kiran Goli, Anita Sargent. Repeat cesarean section in a COVID-19 positive mother in the United States. SAGE Open Medical Case Reports Volume 8: 1–3. 2020.  DOI: 10.1177/2050313X20945536

Study 343 – 32 cases from Jodhpur, India

32 women with Covid-19 during prepgnany were seen over 5 months from April to August 2020 (click here or ijgo.13457). Few details given. The paper is largely concerned with indirect effects of the pandemic. Citation: Goyal, M., Singh, P., Singh, K., Shekhar, S., Agrawal, N. and Misra, S. (2020), The effect of the COVID‐19 pandemic on maternal health due to delay in seeking health care: Experience from a tertiary center. International Journal of Gynecology & Obstetrics. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13457

Study 342 – an update of study 203 from Turkey

The 100 cases in study 203 have been expanded to 533 cases (click here or ijgo.13460). Two women died. There were 131 births and all neonatwes tested negative. Citation: Sahin, D., Tanacan, A., Erol, S.A., Anuk, A.T., Yetiskin, F.D., Keskin, H.L., Ozcan, N., Ozgu‐Erdinc, A.S., Eyi, E.G., Yucel, A., Tayman, C., Unlu, S., Dinc, B., Sari, E., Surel, A.A. and Moraloglu, O.T. (2020), Updated experience of a tertiary pandemic center on 533 pregnant women with COVID‐19 infection: A prospective cohort study from Turkey. Int J Gynecol Obstet. Accepted Author Manuscript. https://doi.org/10.1002/ijgo.13460

5th November update – studies 340 and 341 added

Study 341 – 18 pregnant women with antibodies from Denmark

18/1019 (1.8%) women with stored first trimester serum taken for Down’s screening at Copenhagen University Hospital Hvidovre between Feb 17 & Apr 23 2020, had SARS-CoV-2 antibodies (click here or deaa311). Half had had symptoms. None were hospitalised. One miscarried. Of 36 women who miscarried before Down’s screening, none had antibodies. The positive antibody women may overlap with those in study 299. Citation: la Cour Freiesleben N, Egerup P, Vauvert Römmelmayer Hviid K, Rosenbek Severinsen E, Kolte AM, Westergaard D, Fich Olsen L, Prætorius L, Zedeler A, Hellerung Christiansen AM, Reinhardt Nielsen J, Bang D, Berntsen S, Ollé-López J, Ingham A, Bello-Rodríguez J, Marie Storm D, Ethelberg-Findsen J, Hoffmann ER, Wilken-Jensen C, Stener Jørgensen F, Westh H, Løvendahl Jørgensen H, Nielsen HS. SARS-CoV-2 in first trimester pregnancy: a cohort study. Hum Reprod. 2020 Nov 4:deaa311. doi: 10.1093/humrep/deaa311. Epub ahead of print. PMID: 33145598.

Study 340 – 448 cases from Mexico

448 women in the open national database of COVID-19 from the Ministry of Health between February 28 & May 25, 2020, were pregnant (click here or jogh-10-020512). 137 were hospitalised, 14 admitted to ICU, 7 ventilated and 10 died. Some cases may overlap with those in studies 66 & 271. Citation: Ríos-Silva M, Murillo-Zamora E, Mendoza-Cano O, Trujillo X, Huerta M. COVID-19 mortality among pregnant women in Mexico: A retrospective cohort study. J Glob Health. 2020 Dec;10(2):020512. doi: 10.7189/jogh.10.020512. PMID: 33110595; PMCID: PMC7567444. [important]

4th November update – study 339 added

Study 339 – 65 cases from China

Using the Maternal and Child Health Information Management System of Wuhan, 65 women with Covid-19 delivering between Jan 13 & March 18 were identified and compared with 11,013 women without, or not tested for, Covid-19 (click here or s12916-020-01798-1). The paper was first submitted on 14 May. Despite six revisions the authors fail to make clear, and the referees & editors failed to notice, that most, if not all, of these cases will have been included in studies 1, 2, 6a, 8, 10, 11, 12, 13, 15, 34, 36, 39, 54, 55, 57, 59, 73, 75, 80, 108, 179, 183, 211, 220, 262b, 268, 280, 294, 305, & 329. Citation: Yang, R., Mei, H., Zheng, T. et al. Pregnant women with COVID-19 and risk of adverse birth outcomes and maternal-fetal vertical transmission: a population-based cohort study in Wuhan, China. BMC Med 18, 330 (2020). https://doi.org/10.1186/s12916-020-01798-1

3rd November update – studies 336 to 338 added

Study 338 – birth outcomes among 4,442 pregnancies from the US

5,252 women with laboratory-confirmed SARS-CoV-2 infection were reported from 16 jurisdictions within the Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET), during March 29–October 14, 2020 (click here or mm6944e2-H). 309 pregnancies were presumed ongoing, and 501 had missing outcomes. Among 4,442 women with known pregnancy outcomes there were 3,912 live births with known gestational age, 12.9% were preterm (<37 weeks).  Among 4,527 babies (incl. 79 twins and one set of triplets) 12 (0.3%) pregnancies miscarried before 20 weeks and there was 20 stillbirths (0.4%) after 20 weeks. Among 610 infants with reported SARS-CoV-2 test results, 16 were positive.  Citation: Woodworth KR, Olsen EO, Neelam V, et al. Birth and Infant Outcomes Following Laboratory-Confirmed SARS-CoV-2 Infection in Pregnancy — SET-NET, 16 Jurisdictions, March 29–October 14, 2020. MMWR Morb Mortal Wkly Rep. ePub: 2 November 2020. DOI: http://dx.doi.org/10.15585/mmwr.mm6944e2external icon [important]

Study 337 – 30,415 maternal outcomes from the US

Compared with nonpregnant women of the same age, pregnant women were more frequently admitted to ICU (10.5 versus 3.9 per 1,000 cases), ventilated (2.9 versus 1.1 per 1,000 cases), treated with ECMO (0.7 versus 0.3 per 1,000 cases) (click here or mm6944e3-H). 34/23,434 (1.5 per 1,000) symptomatic pregnant women died, compared with 447/386,028 (1.2 per 1,000) nonpregnant women. Citation: Zambrano LD, Ellington S, Strid P, et al. Update: Characteristics of Symptomatic Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status — United States, January 22–October 3, 2020. MMWR Morb Mortal Wkly Rep. ePub: 2 November 2020. DOI: http://dx.doi.org/10.15585/mmwr.mm6944e3external icon [important]

Study 336 – 5 women from Israel,

Vaginal swabs were tested from 35 women, aged 21-93 years with Covid-19 (click here or 1471-0528.16556). Two were positive. Five of the tested women were in the 3rd trimester of pregnancy, but none of them had a postive vaginal swab. From author affilitions the women were cared for in Lis Maternity Hospital, Tel Aviv, and may therefore be included in study 330. Citation: Schwartz, A., Yogev, Y., Zilberman, A., Alpern, S., Many, A., Yousovich, R. and Gamzu, R. (2020), Detection of SARS‐CoV‐2 in vaginal swabs of women with acute SARS‐CoV‐2 infection: a prospective study.. BJOG: An International Journal of Obstetrics & Gynaecology. Accepted Author Manuscript. doi:10.1111/1471-0528.16556

1st November update – studies 329 to 335 added

Study 335 – Case report from Italy

A woman with Covid-19 at 27 weeks required mechanical ventilation for over 4 weeks, latterly via tracheostomy, and was delivered by Caesarean section at 30 weeks (click here or ccr3.3426). She survived. The baby tested negative and survived. Both were cared for at Ospedali Riuniti Villa Sofia-Cervello, Palermo which has not previously reported cases. Citation: Donzelli, MIppolito, MCatalisano, G, et al. Prone positioning and convalescent plasma therapy in a critically ill pregnant woman with COVID‐19. Clin Case Rep. 2020001– 7https://doi.org/10.1002/ccr3.3426

Study 334 – seroprevalaence among pregnant women, UK

53/1000 (5.3%) of antenatal blood samples, in the Oxford region, between 14 April and 15 June 2020 were positive for SARS-CoV-2 IgG (click here or Lumley eurosurv-25-42-4). Citation: Lumley Sheila F , Eyre David W , McNaughton Anna L , Howarth Alison , Hoosdally Sarah , Hatch Stephanie B , Kavanagh James , Chau Kevin K , Downs Louise O , Cox Stuart , Dunn Laura , Justice Anita , Wareing Susan , Dingle Kate , Rudkin Justine , Auckland Kathryn , Fyfe Alexander , Bolton Jai , Paton Robert , Mentzer Alexander J, Jeffery Katie , Andersson Monique I , James Tim , Peto Tim E A , Marsden Brian D , Screaton Gavin , Cornall Richard J , Klenerman Paul , Ebner Daniel , Stuart David I , Crook Derrick W , Stoesser Nicole , Kennedy Stephen H , Thompson Craig , Gupta Sunetra , Matthews Philippa C ORCID icon. SARS-CoV-2 antibody prevalence, titres and neutralising activity in an antenatal cohort, United Kingdom, 14 April to 15 June 2020. Euro Surveill. 2020;25(42):pii=2001721. https://doi.org/10.2807/1560-
7917.ES.2020.25.41.2001721 

Study 333 – 250 cases from Italy

In this updated series from Lombardy, of 250 pregnant women with either asymptomatic, non-severe, or severe SARS-CoV-2 up to June 18, 2020, nine were admitted to ICU but there were no maternal deaths (click here or ijgo.13435). Some cases were included in studies 32, 64, 114, 180, 188, 197 & 252. Citation: Di Martino, D., Chiaffarino, F., Patanè, L., Prefumo, F., Vergani, P., Ornaghi, S., Savasi, V., Spinillo, A., Cromi, A., D’Ambrosi, F., Tassis, B., Iurlaro, E., Parazzini, F. and Ferrazzi, E. (2020), Assessing risk factors for severe forms of COVID‐19 in a pregnant population: A clinical series from Lombardy, Italy. Int J Gynecol Obstet. Accepted Author Manuscript. doi:10.1002/ijgo.13435

Study 332 – Case report from Granada, West Indies

A woman with Covid-19 gave birth to an infected neonate (click here or Majachani AMCaseRep 925766). The mother had a past history of HIV infection. Both recovered. From author affiliations the unnamed hospital was probably St. George’s University General Hospital, which has not previously reported cases. Citation: Nicole Majachani, Jean Luc M. Francois, Ashen K. Fernando, Jamshed Zuberi. A Case of a Newborn Baby Girl Infected with SARS-CoV-2 Due to Transplacental Viral Transmission. Am J Case Rep 2020; 21:e925766 DOI: 10.12659/AJCR.925766. Available online: 2020-09-17

Study 331 – 180 cases from USA

Of these 180 women with Covid-19 in pregnancy, 7 required intensive care (click here or Janssen AJOG MFM). Three babies tested positive but none had illness consistent with COVID-19. The patients were probably cared for in the Northwell system hospitals in New York, so some have probably been reported in studies 162, 179, 289 & 315.  Citation: Janssen O, Thompson M, Milburn S, Green R, Wagner B, Bianco A, Stroustrup A, The Impact of Perinatal SARS-CoV2 Infection During the Peripartum Period, American Journal of Obstetrics & Gynecology MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100267.&nbsp;

Study 330 – 52 cases from 7 hospitals in Israel

Of 52 women with Covid-19 in pregnancy, one was critically ill, but no babies were infected (click here or Rottenstreich2020_Article_VaginalDeliveryInSARS-CoV-2-in). The seven hospitals are unnamed, but from author affiliations probably include Hadassah-Hebrew University Medical Center, Jerusalem: Sheba Medical Center, Tel-Aviv University, Tel-Hashomer; Mayenei Hayeshua Medical Center, Tel-Aviv University, Ramat Gan; Lis Maternity Hospital, Tel-Aviv; Meir Medical Center, Tel-Aviv University, Kfar Saba; and Ziv Medical Center, Safed. None of these hospitals have reported cases. Citation: Rottenstreich, A., Tsur, A., Braverman, N. et al. Vaginal delivery in SARS-CoV-2-infected pregnant women in Israel: a multicenter prospective analysis. Arch Gynecol Obstet (2020). https://doi.org/10.1007/s00404-020-05854-2

Study 329 – 60 cases from China

These cases (click here or fcimb-10-560899) delivered between January 24 & March 14, 2020 in the Maternity and Child Health Hospital in Wuhan, Hubei province have probabaly been reported many times. The MCH hospital is part of Huazhong University of Science and Technology Hospital grid.488485.d. Studies 8, 17, 30, 38, 54, 55 & 262b. Citation: Sun G, Zhang Y, Liao Q and Cheng Y (2020) Blood Test Results of Pregnant COVID-19 Patients: An Updated Case-Control Study. Front. Cell. Infect. Microbiol. 10:560899. doi: 10.3389/fcimb.2020.560899

31st October update – study 328 added

Study 328 – 154 cases from the Dominican Republic

Of 154 women with Covid-19, 15 developed cardiac injury (click here or Mercedes AJOG PIIS0002937820312060). Two died. The hospital is “an obstetric tertiary level hospital in Santo Domingo”. However none of the authors report an affiliation from that city, which contains more than one large maternity hospital.  Citation: Mercedes BR, Serwat A, Naffaa L, Ramirez N, Khalid F, Steward SB, Caro Feliz OG, Kassab M, Karout L, New-Onset myocardial injury in COVID-19 Pregnant Patients: A Case Series of 15 Patients, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.10.031

28th October – study 327 added

Study 327 – 40 cases of neonatal SARS-CoV-2 from a Spanish registry

A National Registry supported by the Spanish Society of Neonatology identified 40 neonates who tested positive for SARS-CoV-2 between 3 April & 18 May 2020 (click here or fped-08-580584) Citation: Fernández Colomer Belén, Sánchez-Luna Manuel, de Alba Romero Concepción, Alarcón Ana, Baña Souto Ana, Camba Longueira Fátima, Cernada María, Galve Pradell Zenaida, González López María, López Herrera M. Cruz, Ribes Bautista Carmen, Sánchez García Laura, Zamora Flores Elena, Pellicer Adelina, Alonso Díaz Clara, Herraiz Perea Cristina, Romero Ramírez Dolores Sabina, de las Cuevas Terán Isabel, Pescador Chamorro Isabel, Fernández Trisac José Luis, Arruza Gómez Luis, Cardo Fernández Luis Miguel, García García Mª Jesús, Nicolás López Marta, Hortelano López Miryam, Riaza Gómez Mónica, Hernández González Natalio, González Sánchez Raquel, Zambudio Sert Sílvia, Larrosa Capacés Susana, Matías del Pozo Vanesa. Neonatal Infection Due to SARS-CoV-2: An Epidemiological Study in Spain. Frontiers in Pediatrics. VOL 8. 2020. p 670. https://www.frontiersin.org/article/10.3389/fped.2020.580584. DOI 10.3389/fped.2020.580584

25th October – study 326 added

Study 326 – seroprevalence in Paris, France

Of women admitted to the delivery room at Antoine Be´clère Hospital maternity ward from 4th to 31st May, 20/249 (8%) were SARS-CoV-2 IgG positive (click here or journal.pone.0240782). 1/190 tested for nasopharyngeal SARS-CoV-2 RT-PCR was positive. She was asymptomatic and her baby tested negative. The period covered the final week of, and first three weeks post, lockdown. Citation: Mattern J, Vauloup-Fellous C, Zakaria H, Benachi A, Carrara J, Letourneau A, et al. (2020) Post lockdown COVID-19 seroprevalence and circulation at the time of delivery, France. PLoS ONE 15(10): e0240782. https://doi.org/10.1371/journal.pone.0240782.

24 October update – studies 319 to 325 added

Study 325 – Screening in Portugal

Click here. 11/184 (6.0%) of pregnant women screened for SARS-CoV-2 on admission in labour between 19th March and 4th May were positive. Two reported symptoms (click here or ). From author affiliations the hospital was Centro Hospitalar Universitário de São João, Porto. Citation: Figueiredo R, Tavares S, Moucho M, Ramalho C. Systematic screening for SARS-CoV-2 in pregnant women admitted for delivery in a Portuguese maternity. J Perinat Med. 2020 Oct 21:/j/jpme.ahead-of-print/jpm-2020-0387/jpm-2020-0387.xml. doi: 10.1515/jpm-2020-0387. Epub ahead of print. PMID: 33085639.

Study 324 – A case of neonatal SARS in Portugal

Full text not yet available (click here or ). From author affililations this was Hospital de São Francisco Xavier, Centro Hospitalar Lisboa Ocidental, Lisbon. Citation: Correia, Cátia R. MD*; Marçal, Mónica MD*; Vieira, Filipa MD*; Santos, Edmundo MD*; Novais, Cristina MD*; Maria, Ana Teresa MD*; Malveiro, Duarte MD*; Prior, Ana Rita MD*; Aguiar, Marta MD*; Salazar, Anabela MD*; Gouvêa Pinto, Constança MD*; Carvalho Rodrigues, Luís MD†; Pessanha, Maria Ana PhD†; Borges, Vítor PhD‡; Isidro, Joana MSc‡; Gomes, João Paulo PhD‡; Duarte, Sílvia MSc§; Vieira, Luís MSc§; Costa, Inês MSc¶; Alves, Maria João PhD‖; Calhau, Conceição PhD**; Guiomar, Raquel MSc¶; Tuna, Madalena Lopo MD* Congenital SARS-CoV-2 Infection in a Neonate With Severe Acute Respiratory Syndrome, The Pediatric Infectious Disease Journal: October 22, 2020 – Volume Online First – Issue –
doi: 10.1097/INF.0000000000002941 

Study 323 – Two mothers treated with ECMO in USA

Two women with Covid-19 required treatment with ECMO (click here or s-0040-1718694). Both mothers and babies survived. From author affiliations they were cared for in the University of California, Los Angeles. The hospital is not named.  Citation: K. Marie Douglass, Katie M. Strobel, Michael Richley, Thalia Mok  , Annabelle de St Maurice, Viviana Fajardo, Andrew T. Young, Rashmi Rao, Lydia Lee, Peyman Benharash, Alison Chu, Yalda Afshar. Maternal-Neonatal Dyad Outcomes of Maternal COVID-19 Requiring Extracorporeal Membrane Support: A Case Series Am J Perinatol. DOI: 10.1055/s-0040-1718694

Study 322 – 60 cases from Oman

Sixty women with Covid-19 were cared for at The Royal Hospital, Muscat, from March 24 to July 31, 2020 (click here or ijgo.13427). Seven required ITU care of whom one was critically ill. No mothers died. There were four miscarriages, one stillbirth and eight pregnancies ongoing. The remainder of the babies survived. All four tested neonates were negative. Citation: Santhosh, J., Al Salmani, M., Khamis, F., Al Ubaidani, S.A. and Al‐Zakwani, I. (2020), Clinical characteristics of COVID‐19 in pregnant women: A retrospective descriptive single‐center study from a tertiary hospital in Muscat, Oman. International Journal of Gynecology & Obstetrics. Accepted Author Manuscript. doi:10.1002/ijgo.13427

Study 321 – Four cases from Iran

Four pregnant women contracted Covid -19 (click here or Iran case series). All four recovered. One was postnatal, one delivered vaginally and two remained undelivered. They were cared for in Shahid Mostafa Khomeini Hospital in Ilam which has not previously reported cases. Citation: Gheysarzadeh A, Sadeghifard N, Safari M, Rashidian T, Mohammadyari E, Tavan H, Report of four pregnant women getting COVID-19 in Ilam, Iran: Case Series, New Microbes and New Infections, https://doi.org/10.1016/j.nmni.2020.100783.&nbsp;

Study 320 – Case report from USA

A woman with Covid-19 at 36 weeks required 6 days ventilation and delivery by Caesarean (click here or 8889487). She survived, but at the time of the report remained in an inpatient rehabilitation facility. The baby tested negative. From author affiliations she was likely cared for in the Einstein Medical Center, Philadelphia which has not previously reported cases. Citation: Jerald Pelayo ,Gabriella Pugliese, Grace Salacup, Eduardo Quintero, Adeeb Khalifeh, David Jaspan, and Bhavna Sharma. Severe COVID-19 in Third Trimester Pregnancy: Multidisciplinary Approach. Case reports in Critical Care. Volume 2020 |Article ID 8889487 | https://doi.org/10.1155/2020/8889487

Study 319 – No cases in 3 hospitals in Australia

No positive test results among 350 pregnant women from three hospitals in Melbourne over the two-week period 6th to 19th May 2020 (click here or Rolnik 1-s2.0-S1871519220303553-main). This period was after the first wave had subsided. Citation: D.L. Rolnik, T.M. Korman, A. Rindt et al., Coronavirus testing in women attending antenatal care, Women Birth, https://doi.org/10.1016/j.wombi.2020.09.024&nbsp;

20th October update – study 318 added

Study 318 – Case report from Chizhou, Anhui Province, China

A woman contracted Covid-19 on Jan 6th, six months after delivery while still breastfeeding ((click here or 15010_2020_Article_1532). Breastfeeding was stopped and the infant artificially fed at home. The infant’s infection status and outcome were not reported. The mother recovered. Citation: Liu X, Zhou L, Zhu Y. Report on a lactating patient with COVID-19 [published online ahead of print, 2020 Oct 9]. Infection. 2020;1-5. doi:10.1007/s15010-020-01532-2

19th October update – study 317 added

Study 317 – 101 neonates from USA

Of 101 neonates born to 100 mothers positive for SARS-CoV-2 from March 13 to April 24, 2020, two had borderline results and the rest tested negative. No baby had clinical disease (click here or jamapediatrics_dumitriu_2020_oi_200070_1601920765.25034). From author affiliations Columbia University Irving Medical Center. Fourteen babies were reported in study 27. Citation: Dumitriu D, Emeruwa UN, Hanft E, et al. Outcomes of Neonates Born to Mothers With Severe Acute Respiratory Syndrome Coronavirus 2 Infection at a Large Medical Center in New York City. JAMA Pediatr. Published online October 12, 2020. doi:10.1001/jamapediatrics.2020.4298

18th October update – studies 315 and 316 added

Study 316  – Case report from Japan.

A woman with Covid-19 was delivered by caesarean section on April 2nd (click here or jog.14393). This was the first birth to a woman with Covid-19 in Japan. Mother and baby survived. The baby was not infected. They were cared for in the Center for Perinatal, Pediatric and Developmental Medicine, Kitasato University Hospital which has not previously reported cases. Citation: Mochizuki, J., Nakamura, M., Iwahata, S., Nishijima, J., Ito, T., Wada, T., Takayama, Y. and Unno, N. (2020), First report in Japan of a delivery of a woman with the 2019 novel coronavirus disease. J. Obstet. Gynaecol. Res.. doi:10.1111/jog.14393

Study 315 – 31 severe cases from New York

Of 31 pregnant women with severe or critical disease, four had abnormal cardiac biomarkers, of whom two died (click here or PIIS0002937820311881). The women were cared for in the Northwell health system so may have been included in studies 162, 179 and 289. Citation: PACHTMAN SHETTY SL, MEIROWITZ N, BLITZ MJ, GADOMSKI T, WEINBERG CR, Myocardial injury associated with coronavirus disease 2019 in pregnancy, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.10.014. &nbsp;

17 October update – studies 311 to 314 added

Study 314 – 141 cases from USA

Of 141 women with Covid-19 in pregnancy, one died (click here or PIIS2589933320302147 (1)). Of 76 live births, no babies were affected. They were cared for in Yale New Haven, Bridgeport, and Greenwich hospitals. One woman, who had a 22 week termination for severe pre-eclampsia, was reported in study 155. Some may also have been included in study 132. Citation: GRECHUKHINA O, GREENBERG V, LUNDSBERG LS, DESHMUKH U, CATE J, LIPKIND HS, CAMPBELL KH, PETTKER CM, KOHARI KS, REDDY UM, Coronavirus Disease 2019 (COVID-19) pregnancy outcomes in a racially and ethnically diverse population, American Journal of Obstetrics & Gynecology MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100246.

Study 313 – Case report from Mumbai, India

In this MedRxiv preprint, an asymptomatic woman tested positive for SARS-CoV-2 at 8 weeks gestation. At 13 weeks the fetus had died (click here or 2020.08.18.20177121v1.full). The authors detected virus in the placenta and argue the fetal demise was due to congenital transmission of SARS-CoV-2. Citation: Prajakta Shende, Pradip Gaikwad, Manisha Gandhewar, Pawankumar Ukey, Anshul Bhide, Vainav Patel, Sharad Bhagat, Vikrant Bhor, Smita Mahale, Rahul Gajbhiye, Deepak Modi Persistence of SARS-CoV-2 in the first trimester placenta leading to vertical transmission and fetal demise from an asymptomatic mother. medRxiv 2020.08.18.20177121; doi: https://doi.org/10.1101/2020.08.18.20177121. 29 December update. Published in Human Reproduction (click here). Citation: Shende P, Gaikwad P, Gandhewar M, Ukey P, Bhide A, Patel V, Bhagat S, Bhor V, Mahale S, Gajbhiye R, Modi D. Persistence of SARS-CoV-2 in the first trimester placenta leading to transplacental transmission and fetal demise from an asymptomatic mother. Hum Reprod. 2020 Dec 21:deaa367. doi: 10.1093/humrep/deaa367. Epub ahead of print. PMID: 33346816.

Study 312 – analysis of a range of specimens from 31 affected pregnancies in Italy

31 pregnancies with SARS-CoV-2 (click here or s41467-020-18933-4). From author affiliations the patients were probably cared for in Milan. Citation: Fenizia, C., Biasin, M., Cetin, I. et al. Analysis of SARS-CoV-2 vertical transmission during pregnancy. Nat Commun 11, 5128 (2020). https://doi.org/10.1038/s41467-020-18933-4

Study 311 – 21 placentas from St Louis, USA

No differences were seen between 21 placentas from SARS-CoV-2 positive pregnancies and 20 control ones (click here or Histopathology of Third Trimester Placenta from SARS CoV 2 Positive Women). The hospitals are not reported. Citation: Mai He, Priya Skaria, Kasey Kreutz, Ling Chen, Ian S. Hagemann, Ebony B. Carter, Indira U. Mysorekar, D. Michael Nelson, John Pfeifer & Louis P. Dehner (2020) Histopathology of Third Trimester Placenta from SARS-CoV-2-Positive Women, Fetal and Pediatric Pathology, DOI: 10.1080/15513815.2020.1828517

13 October update – studies 309 and 310 added

Study 310 – 86 pregnant women treated with remdesivir

Of the first 86 pregnant, or recently pregnant, women with severe Covid-19 (O2 satuation <=94%), treated with compassionate use remdesivir (all outside a trial) between March 21, & April 22nd 2020, 63 were admitted to ICU, 45 required ventilation and one ECMO (click here or ciaa1466). One woman died. At 28-day follow-up seven women were still being ventilated (appendix Fig 2 ciaa1466_suppl_supplementary_materials_1 (1)).  Among 45 deliveries there was one 17 weeks miscarriage but otherwise no babies died. Four women were treated in Spain, two in Switzerland and one each in Italy and the UK. The rest were from the United States. Many have presumably been included in other reports. Citation: Richard M Burwick, Sigal Yawetz, Kathryn E Stephenson, Ai-Ris Y Collier, Pritha Sen, Brian G Blackburn, E Milunka Kojic, Adi Hirshberg, Jose F Suarez, Magdalena E Sobieszczyk, Kristen M Marks, Shawn Mazur, Cecilia Big, Oriol Manuel, Gregory Morlin, Suzanne J Rose, Mariam Naqvi, Ilona T Goldfarb, Adam DeZure, Laura Telep, Susanna K Tan, Yang Zhao, Tom Hahambis, Jason Hindman, Anand P Chokkalingam, Christoph Carter, Moupali Das, Anu O Osinusi, Diana M Brainard, Tilly A Varughese, Olga Kovalenko, Matthew D Sims, Samit Desai, Geeta Swamy, Jeanne S Sheffield, Rebecca Zash, William R Short, Compassionate Use of Remdesivir in Pregnant Women with Severe Covid-19, Clinical Infectious Diseases, , ciaa1466, https://doi.org/10.1093/cid/ciaa1466

Study 309 – 2,475 pregnant women with Covid-19 from Brazil

Among 2,475 women identified through an acute respiratory distress register, 494 were admitted to ITU, 242 underwent invasive ventilation and 204 died (click here or ijgo.13407). Among the women who died, 8 (6%) had not reached hospital, 81 (40%) had not been admitted to intensive care, and 52 (26%) had no access to any respiratory support before dying. These are updated figures from studies 182, 248 & 249. Citation: Menezes, M.O., Takemoto, M.L., Nakamura‐Pereira, M., Katz, L., Amorim, M.M., Salgado, H.O., Melo, A., Diniz, C.S., de Sousa, L.A., Magalhaes, C.G., Knobel, R., Andreucci, C.B. and (2020), Risk factors for adverse outcomes among pregnant and postpartum women with acute respiratory distress syndrome due to COVID‐19 in Brazil. Int J Gynecol Obstet. Accepted Author Manuscript. doi:10.1002/ijgo.13407  [important]

12 October update – studies 303 to 308 added.  Study 167 publication updated.

Study 308 – Case report from Korea

One case report of Covid-19 in pregnancy plus 12 further cases mentioned in the final pragraph (click here or ogs-20106). All cared for at Daegu Fatima Hospital or Daegu Dongsan Hospital and likely overlap with those in studies 22 & 143.  Citation: Jin-Gon Bae , Jin-Kyeong Ha, Myoung Kwon, Hak-Youle Park, Won-Joon Seong, Seong-Yeon Hong. A case of delivery of a pregnant woman with COVID-19 infection in Daegu, Korea. Obstet Gynecol Sci > Epub ahead of print  Case Report DOI: https://doi.org/10.5468/ogs.20106 [Epub ahead of print] Published online October 5, 2020.

Study 307 – 257 cases from Europe and other continents

These cases (click here or PIIS0301211520306400) probably overlap considerably with those reported in study 278. Citation: Di Mascio D, D’Antonio F, Perinatal mortality and morbidity of SARS-COV-2 infection during pregnancy in European countries: findings from an international study, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.10.009

Study 306 – Neonatal death in Ilam province, Iran

The mother had Covid-19 (click here or 13256_2020_Article_2519). The baby, delivered by elective caesarean at 39 weeks, had normal Apgar scores but collapsed soon after birth and died. Maternal SARS-CoV-2 swabs were positive, and baby swabs negative. The birth was at Zagros Hospital and the baby was later transferred to Ayatollah Taleghani Hospital, both in Ivan City, and neither of which have previously reported caes. Citation: Rashidian, T., Sharifi, N., Fathnezhad-Kazemi, A. et al. Death of a neonate with suspected coronavirus disease 2019 born to a mother with coronavirus disease 2019 in Iran: a case report. J Med Case Reports 14, 186 (2020). https://doi.org/10.1186/s13256-020-02519-1

Study 305 – Two cases from Wuhan, China

These two women with Covid-19 in pregnancy have probably been reported already (click here or s12884-020-03281-4). Citation: Cao, D., Chen, M., Peng, M. et al. Vaginal delivery in women with COVID-19: report of two cases. BMC Pregnancy Childbirth 20, 580 (2020). https://doi.org/10.1186/s12884-020-03281-4

Study 304 – 32 pregnant women admitted to ITU in the USA

Thirty two pregnant women with Covid-19 were admitted to ITU in multiple US hospitals (click here or rccm.202006-2182le). Citation: Sarah Rae Easter, Shruti Gupta, Samantha K. Brenner, David E. Leaf Outcomes of Critically Ill Pregnant Women with COVID-19 in the United States. American Journal of Respiratory and Critical Care Medicine Published Online: October 07, 2020 https://doi.org/10.1164/rccm.202006-2182LE

Study 303 – Case report from Turkey

This case report from (judging by author affiliations) Recep Tayyip Erdoğan University School of Medicine, Rize (click here or 354-356) may have been reported in studies 244 and 277Citation: Özçelik N, Özdemir S, Gürlek B, Yıldız İE. COVID-19 Pregnant Patient Management with a Case of COVID-19 Patient with An Uncomplicated Delivery. Turk Thorac J. 2020 Sep;21(5):354-356. doi: 10.5152/TurkThoracJ.2020.20135. Epub 2020 Sep 1. PMID: 33031729.

11 October update – study 302 added

Study 302 – Two cases of repeat SARS-CoV-2 positivity in pregnancy from Italy

A pregnant women who had recovered from mild Covid-19 in March 2020 at 24 weeks, retested positive when she gave birth in July at 41 weeks. Another asymptomatic women with SARS-CoV-2 in April at 32 weeks gestation, who had later tested negative, tested positive again at birth in June (click here or 1471-0528.16362). From author affiliations both cases were probably cared for in Brescia which means they were likely included in studies 32, 64 & 252. Citation: Zanardini, C., Saccani, B., Franceschetti, l., Zatti, S., Sartori, E. and Prefumo, F. (2020), Retest positive for SARS‐CoV‐2 RNA of recovered pregnant women with COVID‐19. Ultrasound Obstet Gynecol. Accepted Author Manuscript. doi:10.1002/uog.23144

10 October update – study 301 added

Study 301 – 736 women in the US PRIORITY study

The clinical features of 736 pregnant women with Covid-19 (594 SARS-CoV-2 positive), recruited through social media in the PRIORITY study, are reported (click here or 1471-0528.16362). They will overlap with study 281 and many other US reports. Citation: Afshar, Yalda MD, PhD; Gaw, Stephanie L. MD, PhD; Flaherman, Valerie J. MD; Chambers, Brittany D. PhD, MPH; Krakow, Deborah MD; Berghella, Vincenzo MD; Shamshirsaz, Alireza A. MD; Boatin, Adeline A. MD, MPH; Aldrovandi, Grace MD; Greiner, Andrea MD; Riley, Laura MD; Boscardin, W. John PhD; Jamieson, Denise J. MD; Jacoby, Vanessa L. MD, MAS, on behalf of the Pregnancy CoRonavIrus Outcomes RegIsTrY (PRIORITY) Study Clinical Presentation of Coronavirus Disease 2019 (COVID-19) in Pregnant and Recently Pregnant People, Obstetrics & Gynecology: October 07, 2020 – Volume Latest Articles – Issue – 10.1097/AOG.0000000000004178 doi: 10.1097/AOG.0000000000004178

9 October update – study 300 added

Study 300 – 26 cases from Dublin, Ireland

26 women had SARS-CoV-2 detected during pregnancy by PCR in the Rotunda Hospital between 1st March & 1st July 2020 (click here or Infants-Born-to-Mothers-with-COVID-19-During-Pregnancy-The-First-Four-Months-of-the-Pandemic). Maternal survival was not reported but, by implication, was good. All infants survived and none were infected. These case are probably included in study 284. Citation: C. Murphy, D. O’Reilly, N. McCallion, R. Drew, W. Ferguson. Infants Born to Mothers with COVID-19 During Pregnancy: The First Four Months of the Pandemic Ir Med J; Vol 113; No. 9; P193

8 October update – study 299 added

Study 299 – 29 women with anti SARS-CoV-2 antibodies from Denmark

Of the 29 women reported in this Medxiv preprint, 15 had previously had Covid-19 symptoms, but none had a positive swab (click here or 2020.09.14.20191106v1.full). They were cared for at Copenhagen University Hospital, Hvidovre, which has not previously reported cases. Citation; Pia Egerup, Line Fich Olsen, Ann-Marie Hellerung Christiansen, David Westergaard, Elin Rosenbek Severinsen, Kathrine Vauvert Roemmelmayer Hviid, Astrid Marie Kolte, Amalie Dyhrberg Boje, Marie-Louise Mathilde Friis Bertelsen, Lisbeth Praetorius, Anne Zedeler, Josefine Reinhardt Nielsen, Didi Bang, Sine Berntsen, Jeppe Ethelberg-Findsen, Ditte Marie Storm, Judith Bello-Rodriguez, Andreas Ingham, Joaquim Olle-Lopez, Eva Hoffmann, Charlotte Wilken-Jensen, Lone Krebs, Finn Stener Joergensen, Henrik Torkil Westh, Henrik Lovendahl Jorgensen, Nina la Cour Freiesleben, Henriette Svarre Nielsen medRxiv 2020.09.14.20191106; doi: https://doi.org/10.1101/2020.09.14.20191106

5 October update – studies 292 to 298 added

Study 298 – 67 cases from Sweden

The authors claim that these 67 pregnant women with SARS-CoV-2 comprise all those cared for in the Stockholm region between March 19 & April 26, 2020 (click here or aogs.14006). Four women were admitted to intensive care but none died. Three babies were infected. Two babies died. From author affliliations the unnamed hospitals probably include Karolinska, Södersjukhuset (Southern), Danderyd, and Södertälje hospitals. The series likely includes some women reported in studies 20, 88, and 282. Study 282 reported 156 women with SARS-Cov-2 admitted in labour to the Karolinska alone, albeit over a longer time period March 25 to July 24 (study 282). Citation: Remaeus, K., Savchenko, J., Brismar Wendel, S., Gidlöf, S.B., Graner, S., Jones, E., Molin, J., Saltvedt, S., Wallström, T. and Pettersson, K. (2020), Characteristics and short‐term obstetric outcomes in a case series of 67 women tested positive for SARS‐CoV‐2 in Stockholm, Sweden. Acta Obstet Gynecol Scand. Accepted Author Manuscript. doi:10.1111/aogs.14006

Study 297 – anti SARS-CoV-2 IgA in breastmilk within 72 hr of birth

A woman with a clinical diagnosis of Covid-19, but with negative PCR tests, delivered by Caesarean at 37 weeks (click here or 0890334420960433). Anti SARS-CoV-2 IgA was detected in breast milk soon after birth. The baby was not infected. From author affiliations the hospital was probably Municipal Universitário de São Bernardo do Campo, Brazil, which has not previously reported cases. Citation: Lebrão CW, Cruz MN, Silva MH da, et al. Early Identification of IgA Anti-SARSCoV-2 in Milk of Mother With COVID-19 Infection. Journal of Human Lactation. September 2020. doi:10.1177/0890334420960433

Study 296 – Case report from USA

A woman wih Covid-19 developed pre-eclampsia at 34 weeks (click here or main). Both her and the baby recovered. From author affiliations the hospital was probably Maine Medical Center, Portland, Maine, which has not previously reported cases. Citation: J.N. Hansen, J. Hine and T.D. Strout, COVID-19 and preeclampsia with severe features at 34-weeks gestation, American Journal of Emergency Medicine, https://doi.org/10.1016/j.ajem.2020.06.052

Study 295 – Takotsubo cardiomyopathy in pregnancy & SARS-CoV-2

The first report of Takotsubo cardiomyopathy in pregnancy in association with SARS-CoV-2 infection (click here or e239104.full). The mother was delivered by caesarean and recovered. Baby outcomes were not reported. The hospital was probably Gauhati Medical College and Hospital, Guwahati, India, which has not previously reported cases. Citation: Bhattacharyya PJAttri PKFarooqui W. Takotsubo cardiomyopathy in early term pregnancy: a rare cardiac complication of SARS-CoV-2 infection.

Study 294 – 16 women with SARS-CoV-2 infection from China

16 pregnant women with SARS-CoV-2 infection (click here or Zhou2020_Article_TheMetabolicAndImmunologicalCh). From author affiliations and ethics committee review the hospital was probably Renmin Hospital of Wuhan University grid.412632.0, which means the cases probably overlap with those in studies 6a, 10, 12, 36, 37, and 40. Citation: Zhou, J., Wang, Y., Zhao, J. et al. The metabolic and immunological characteristics of pregnant women with COVID-19 and their neonates. Eur J Clin Microbiol Infect Dis (2020). https://doi.org/10.1007/s10096-020-04033-0

Study 293 – Infected triplets from Oman

All three triplets born by Caesarean at 32 weeks to a woman with Covid-19 were infected (click here or IS_VERTICAL_TRANSMISSION_OF_SARS_CoV_2_INFECTION.96038). They all thrived. The woman was cared for at Khoula Hospital, Muscat, which has not previously reported cases. Citation: Alwardi, Talal Hamood; Ramdas, Vidya; Al Yahmadi, Mohammed; Al Aisari, Salima; Bhandari, Satish; Saif Al Hashami, Hilal; Al Jabri, Amal; Manikoth, Prakash; Malviya, Manoj. IS VERTICAL TRANSMISSION OF SARS-CoV-2 INFECTION POSSIBLE IN PRETERM TRIPLET PREGNANCY? A CASE SERIES, The Pediatric Infectious Disease Journal: September 25, 2020 – Volume Online First – Issue – doi: 10.1097/INF.0000000000002926 

Study 292 – Blood loss at birth among 53 women in USA

The blood loss at birth among 53 women with Covid 19 was no different from women without the disease (click here or s-0040-1718403). Women were cared for in Boston Medical Center which has not previously reported cases. Citation: Wang MJ, Schapero M, Iverson R, Yarrington CD. Obstetric Hemorrhage Risk Associated with Novel COVID-19 Diagnosis from a Single-Institution Cohort in the United States. Am J Perinatol. 2020 Sep 29. doi: 10.1055/s-0040-1718403. Epub ahead of print. PMID: 32992351.

28 September update – study 291 added

Study 291 – Spanish registry of Covid-19 screening in asymptomatic pregnant women

By May 31st 2020, of 16,308 pregnant women screened, 338 (2.1%) had tested positive (click here or RS94C_202009092). Testing was done in 100 maternity hospitals listed in Table 2. This is a different registry from study 264b, which only covered 45 hospitals. However the hospitals, time period and presumably cases overlap.  Spanish with English abstract. Citation: Encinas Pardilla MB, Caño Aguilar Á, Marcos Puig B, Sanz Lorenzana A, Rodríguez de la Torre I, Hernando López de la Manzanara P, Fernández Bernardo A, Martínez Pérez Ó. Registro español de cribado de Covid-19 en gestantes asintomáticas. Rev Esp Salud Pública. 2020; 94: 18 de septiembre e202009092

27 September update – studies 284-290 added. I’ve also noticed ten duplicate numbers, studies 257 to 266 & renumbered the later ones as 257b to 266b

Study 290 – 25 symptomatic women in USA

25/532 (4.7%) women admitted for an obstetric procedure were asymptomatic but positive for SARS-CoV-2 at Barnes-Jewish Hospital in St Louis, Missouri from May 28 – July 22 (click here or PIIS0002937820311029). This series will not include the severely ill woman in study 69, but probably includes some in study 259. Citation: KELLY JC, RAGHURAMAN N, PALANISAMY A, STOUT MJ, CARTER EB, Pre-procedural asymptomatic COVID-19 in obstetric and surgical units, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.09.023.

Study 289 – seroprevalence during labour in New York State

269/1671 (16%) women were seropositive in labour (click here or Haizler-Cohen PIIS0002937820311017). They delivered in 7 hospitals in the Northwell Health system so probably were included in studies 162 and 179. Citation: HAIZLER-COHEN L, DAVIDOV A, BLITZ MJ, FRUHMAN G, SARS-CoV-2 Antibodies in Pregnant Women Admitted to Labor and Delivery, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.09.022.

Study 288 – serological testing among pregnant women in Estonia

The SARS-CoV-2 seroprevalemce was reported to be nearly five time higher than the rate of PCR positivity, and also 10 times lower than the rate of seropositivity in the general population of Spain (sic) (click here or aogs.13995) Citation: Veerus, P., Salumets, A., Naaber, P., Krjutškov, K., Tilk, K., Laanpere, M. and Uusküla, A. (2020), Seroprevalence of SARS‐CoV‐2 antibodies among pregnant women in Estonia: a call for epidemiological studies. Acta Obstetricia et Gynecologica Scandinavica. Accepted Author Manuscript. doi:10.1111/aogs.13995

Study 287 – 2 cases from Iran

A woman with severe Covid-19 at 31 weeks was delivered by Caesarean and died in Shariati hospital, Tehran. Her baby was seriously ill with complications of prematurity and neonatal Covid-19. He recovered, albeit with hydrocephalus (click here or s13052-020-00897-2). A second women had milder disease diagnosed clinically. Her baby also had complications of prematurity and neonatal Covid-19 and recoverd. The mothers may have been included in studies 66, 67 and 218. The babies may have been reported in study 250. Citation: Sagheb, S., Lamsehchi, A., Jafary, M. et al. Two seriously ill neonates born to mothers with COVID-19 pneumonia- a case report. Ital J Pediatr 46, 137 (2020). https://doi.org/10.1186/s13052-020-00897-2

Study 286 – 52 cases from Turkey

27 women with Covid-99 in pregnancy confirmed on PCR, and 25 diagnosed clinically (click here or Alay jog.14493 (1)). From author affiliations the unnamed tertiary referral hospital is probably Dr. Sadi Konuk Education and Training Hospital, Istanbul, which has not previously reported cases on its own behalf. They may be included in other Istanbul series such as study 244. It also appears to be a different hospital from Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital which is nearby, and reported cases in studies 144 and 210. Citation: Alay, I., Yildiz, S., Kaya, C., Yasar, K.K., Aydin, O.A., Karaosmanoglu, H.K., Aydeniz, B., Salihoglu, O., Yaşar, L. and Ekin, M. (2020), The clinical findings and outcomes of symptomatic pregnant women diagnosed with or suspected of having coronavirus disease 2019 in a tertiary pandemic hospital in Istanbul, Turkey. J. Obstet. Gynaecol. Res.. doi:10.1111/jog.14493

Study 285 – 61 cases from New Jersey, USA

A case control study including 61 women with confirmed COVID-19 in pregnancy (click here or Brandt PIIS0002937820311340). The women were cared for at the Robert Wood Johnson University Hospital, in New Brunswick, which also reported cases in study 86. Citation: BRANDT JS, HILL J, REDDY A, SCHUSTER M, PATRICK HS, ROSEN T, SAUER MV, BOYLE C, ANANTH CV, Epidemiology of COVID-19 in Pregnancy: Risk Factors and Associations with Adverse Maternal and Neonatal Outcomes American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.09.043.

Study 284 – 70 cases from the Republic of Ireland’s Covid-19 register

70 women tested positive for SARS-CoV-2 during pregnancy in March and April 2020 (click here). There were no maternal deaths (pers comm Keelin O’Donoghue). The first report from the Republic of Ireland. Citation: ROI COVID-19 Study https://www.ucc.ie/en/npec/roicovid-19study/ Accessed 27 Sept 2020

24th September update – study 283 added

Study 283 – 321 cases from India

This first report from the Indian PregCOVID registry reports 141 pregnant women testing positive for SARS-CoV-2 in 15 hospitals in Maharashtra state (click here or PIIS0301211520306084). To these are added a further 180 cases from Topiwala National Medical College & BYL Nair Charitable Hospital, grid.413161.0, a dedicated Covid-19 hospital in Mumbai. The registry hospitals are listed and appear to have not previously reported cases. Note Lokmanya Tilak Municipal General Hospital and Lokmanya Tilak Municipal Medical College, in Mumbai grid.415652.1, study 245, does not appear to be part of the registry. The Nair hospital cases may overlap with those in study 225. Citation: Waghmare R, Gajbhiye R, Mahajan N, Modi D, Mukherjee S, Mahale S, Universal screening identifies asymptomatic carriers of SARS-CoV-2 among pregnant women in India, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.09.030

23 September update – study 282 added

Study 282 – 156 cases from Sweden

Of 156 pregant women seen at the Karolinska Hospital in Stockoholm who tested positive for SARS-CoV-2, 65% were asymptomatic (click here or  jama_ahlberg_2020_ld_200101_1600871779.60882). There was one stillbirth. Maternal deaths were not reported. Compared with a control group matched on various factors there was an increase in pre-eclampsia but no increase in preterm birth. This is the first report from this hospital. The cases don’t overlap with those reported in studies 20 or 259, but likely overlap with some in study 88. Citation: Ahlberg M, Neovius M, Saltvedt S, et al. Association of SARS-CoV-2 Test Status and Pregnancy Outcomes. JAMA. Published online September 23, 2020. doi:10.1001/jama.2020.19124

21 September update – study 281 added

Study 281 – First report from the US PRIORITY Study 

The PRIORITY study collected self-reported cases of Covid-19 in pregnancy. In this report they describe the outcomes of 179 infants born to mothers who had tested positive and 84 who tested negative. 82% of the former group and 63% of the latter had symptoms (click here or ciaa1411). 44 babies were admitted to NICU, and two were infected. Although not explicitly stated there appear to have been no stillbirths or neonatal deaths. Births occurred at over 100 hospitals across the US so it is likely that many will have been included in other US reports. Citation: Valerie J Flaherman, MD, MPH, Yalda Afshar, MD, PHD, John Boscardin, PHD, Roberta L Keller, MD, Anne Mardy, MD, Mary K Prahl, MD, Carolyn Phillips, MD, Ifeyinwa V Asiodu, RN, PHD, W Vincenzo Berghella, MD, Brittany D Chambers, PHD, Joia Crear-Perry, MD, Denise J Jamieson, MD, MPH, Vanessa L Jacoby, MD, MAS, Stephanie L Gaw, MD, PHD, Infant Outcomes Following Maternal Infection with SARS-CoV-2: First Report from the PRIORITY Study, Clinical Infectious Diseases, ciaa1411, https://doi.org/10.1093/cid/ciaa1411

20 September update – study 274 belatedly added (we’d missed it on 8 June). Studies 275 to 280 also added

Study 280 – Case report from China

A woman with Covid-19 gave birth on March 6th. The baby was not infected (click here or 5f3fc192e7305c00087df995). The hospital was Wuhan Central Hospital grid.440160.7 which presumably reported this case in study 39. Citation: Gao WDeng ZZeng LYang YGong HLiu JXiao H. A newborn with normal IgM and elevated IgG antibodies born to an asymptomatic infection mother with COVID-19. Aging (Albany NY). 2020; 12:16672-16674. https://doi.org/10.18632/aging.103346

Study 279 – The first case of Covid-19 in pregnancy in the USA

A woman with Covid-19 presented to New York City Health and Hospitals/Lincoln on March 12, 2020 (click here or 9795-IN PRESS-52450-5-10-20200908). She had mild disease, was treated as an outpatient and recovered. She was delivered by Caesarean at 37 weeks and the baby was not infected. The authors claim this was the first case of Covid-19 in pregnancy in the US. They may be correct. However the paper title is misleading because it was not a case of intrauterine transmission. Citation: Elkafrawi D, Joseph J, Schiattarella A, Rodriguez B, Sisti G. Intrauterine transmission of COVID-19 in Pregnancy: case report and review of literature. Acta Bio Med [Internet]. 2020Sep.7 [cited 2020Sep.20];91(3):e2020041. Available from: https://www.mattioli1885journals.com/index.php/actabiomedica/article/view/9795

Study 278 – 388 mothers testing positive for SARS-COV-2 from 22 countries.

The World Association of Perinatal Medicine Covid-19 working group has collected 388 women, pregnant with singletons, and diagnosed with SARS-CoV-19 between February 1 and April 30, 2020, from 73 centers in 22 countries (Argentina, Australia, Belgium, Brazil, Colombia, Czech Republic, Finland, Germany, Greece, Israel, Italy, North Macedonia, Peru, Portugal, Republic of
Kosovo, Romania, Russia, Serbia, Slovenia, Spain, Turkey, and United States (click here or uog.23107). Three mothers died. Of 266 completed pregnancies there were 6 miscarriages, 3 pregnancy terminations, and 6 stillbirths. Of 251 livebirths, 5 neonates died. The centres are listed in the supplement here uog23107-sup-0001-supinfo and many appear to have not previously reported cases. However the number of cases per centre is not reported and there is no explicit statement about previous reports. Citation: Di Mascio, D. and the WAPM (The World Association of Perinatal Medicine) working group on COVID‐19 (2020), Maternal and Perinatal Outcomes of Pregnant Women with SARS‐COV‐2 infection. Ultrasound Obstet Gynecol. Accepted Author Manuscript. doi:10.1002/uog.23107

Study 277 – 37 Neonates with community acquired Covid-19 in Turkey

This series of 37 neonates with Covid-91 acquired in the community were collected from 24 neonatal intensive care units around Turkey (click here or A_Multicentered_Study_on_Epidemiologic_and.2). Those born to mothers with SARS-CoV-2 during pregnancy were excluded. One with Down’s syndrome died. Citation: Kanburoglu, Mehmet Kenan; Tayman, Cuneyt; Oncel, Mehmet Yekta; Akin, Ilke Mungan; Can, Emrah; Demir, Nihat; Arayici, Sema; Baser, Demet Orhan; Caner, Ibrahim; Memisoglu, Asli; Uygun, Saime Sundus; Akar, Selahattin; Akin, Mustafa Ali; Ataoglu, Emel; Bezirganoglu, Handan; Bilgin, Leyla; Bozdag, Senol; Comert, Serdar; Gurpinar, Resat; Imamoglu, Ebru Yalin; Imdadoglu, Timucin; Narter, Fatma; Ozdemir, Ramazan; Toptan, Handan Hakyemez; Yalinbas, Emine Esin; Yaman, Akan; Erdeve, Omer; Koc, Esin. A Multicentered Study on Epidemiologic and Clinical Characteristics of 37 Neonates With Community-acquired COVID-19, The Pediatric Infectious Disease Journal: October 2020 – Volume 39 – Issue 10 – p e297-e302
doi: 10.1097/INF.0000000000002862 

Study 276 – a case treated with Remdesivir from USA

A woman with severe Covid-19 requiring supplemental oxygen but not invasive ventilation was treated with hydroxychloroquine and remdesivir (click here or ofaa345). She recovered and later gave birth vaginally. She was a health care worker caring for COVID-19 patients. From author affiliations this was NewYork-Presbyterian Hospital, Weill Cornell Medical Center, so she may have been included in studies 99, 230, 234 and 270 and possibly other series.  Citation: Grace A Maldarelli, MD, PhD, Megan Savage, MD, Shawn Mazur, PharmD, Corrina Oxford-Horrey, MD, Mirella Salvatore, MD, Kristen M Marks, MD, Remdesivir treatment for severe COVID-19 in third-trimester pregnancy: Case report and management discussion, Open Forum Infectious Diseases, , ofaa345, https://doi.org/10.1093/ofid/ofaa345

Study 275 – 20 women infected with SARS-CoV-2 and pre-eclampsia from Peru

20 women with SARS-CoV-2 also developed pre-eclampsia (click here or PIIS0301211520305959). Two babies died. One baby tested positive. One woman require hysterectomy for placenta accreata. Patients were cared for at Hospital Nacional Edgardo Rebagliati Martins, Lima, and, as acknowledged by the authors, they overlap with those reported in study 274. Citation: Coronado-Arroyo JC, Concepcion-Zavaleta MJ, Zavaleta-Gutierrez FE, Concepcion-Urteaga LA, Is COVID-19 a risk factor for severe preeclampsia? Hospital experience in a developing country, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.09.020&nbsp;

Study 274 – 41 patients from Peru

Of 41 women with Covid-19 in pregnancy, treated  between March 24 & May 7, 2020, none died although two required non invasive ventilation. Report in Spanish (click here). English translation (available here or 2245-6876-2-PB). From author affiliations the patients were cared for in Edgardo Rebagliati Martins National Hospital, Lima. One baby was infected. This is a different hospital from the case in study 51. Citation: Huerta Saenz IH, Elías Estrada JC, Campos Del Castillo K, Muñoz Taya R, Cristina Coronado J. Maternal and perinatal characteristics of pregnant women with COVID-19 in a national hospital in Lima, Peru. Rev Peru Ginecol Obstet. 2020;66(2). DOI: https://doi.org/10.31403/rpgo.v66i2245&nbsp;

16 September update – studies 272 & 273 added.

Study 273 – 598 cases from US COVID-NET hospitals

598 hospitalized women with COVID-19, cared for in the COVID-19-Associated Hospitalization Surveillance Network (COVID-NET) were pregnant (click here or mm6938e1-H). 44 mothers were admitted to ICU, 23 required invasive mechanical ventilation, and two died. COVID-NET covers 99 counties in 14 US states, which amounts to about 10% of the US population. The cases likely overlap with those in previous COVID-NET reports, studies 171 and 173. Citation: Delahoy MJ, Whitaker M, O’Halloran A, et al. Characteristics and Maternal and Birth Outcomes of Hospitalized Pregnant Women with Laboratory-Confirmed COVID-19 — COVID-NET, 13 States, March 1–August 22, 2020. MMWR Morb Mortal Wkly Rep. ePub: 16 September 2020. DOI: http://dx.doi.org/10.15585/mmwr.mm6938e1

Study 272 – 105 cases from eight US hospitals participating in vaccine surveillance

Among 105 pregnant women admitted with SARS-CoV-2 infection to eight hospitals participating in a Vaccine Safety Datalink (VSD) surveillance project, over half were admitted for obstetric reasons (click here or mm6938e2-H). The participating hospitals are listed here. Citation: Panagiotakopoulos L, Myers TR, Gee J, et al. SARS-CoV-2 Infection Among Hospitalized Pregnant Women: Reasons for Admission and Pregnancy Characteristics — Eight U.S. Health Care Centers, March 1–May 30, 2020. MMWR Morb Mortal Wkly Rep. ePub: 16 September 2020. DOI: http://dx.doi.org/10.15585/mmwr.mm6938e2external icon

14 September update – study 270 added

Study 271 – 86 “extra” maternal deaths during pandemic in Mexico

These authors used publicly available goverment statisitics (click here) to estimate the excess maternal deaths from Covid-19 in Mexico in 2020 (click here or Excess_Maternal_Deaths_Associated_With_Coronavirus.97254). The predicted maternal mortality ratio was 29.5 per 100,000 live births, and so far in 2020 the actual ratio is 42.4. The excess was entirely confined to respiratory disease. Overall 86 “extra” deaths have ocurred. In comparison the 168 deaths officially reported as due to respiratory disease are made up of 109 deaths due to confirmed COVID-19, 34 for which COVID-19 needs to be confirmed, and 25 due to other respiratory diseases. Citation: Lumbreras-Marquez, Mario I. MBBS, MMSc; Campos-Zamora, Melissa MBBS, MMSc; Seifert, Sara M. MD; Kim, Jimin MD, MSc; Lumbreras-Marquez, Jesus MBBS; Vazquez-Alaniz, Fernando PhD; Fields, Kara G. MS; Farber, Michaela K. MD, MS Excess Maternal Deaths Associated With Coronavirus Disease 2019 (COVID-19) in Mexico, Obstetrics & Gynecology: September 09, 2020 – Volume Publish Ahead of Print – Issue – doi: 10.1097/AOG.0000000000004140 [important]

13 September update – studies 267-270 added

Study 270 – more from USA

Not clear from abstract if this includes original data (click here or [16193997 – Journal of Perinatal Medicine] COVID-19 in obstetrics 2020). Citation: Dayal, A. K., Razavi, A. S., Jaffer, A. K., Prasad, N., & Skupski, D. W. (2020). COVID-19 in obstetrics 2020: the experience at a New York City medical center, Journal of Perinatal Medicine (published online ahead of print 2020), 000010151520200365. doi: https://doi.org/10.1515/jpm-2020-0365

Study 269 – Case report from USA

A woman with Covid-19 ruptured her membranes at 19 weeks, and delivered vaginally at 29 weeks (click here or Haiti 8847859 (1)). The baby tested negative but suffered complications of prematurity and remains on ICU. From author affiliations the hospital was probably University of Maryland Medical Center, Baltimore, which has not previously repoted cases. Citation: Mary E. Burgoyne, Emad A. Elsamadicy, Liviu Cojocaru, Andrea Desai, “COVID-19 Barriers to Care for Pregnant Patients in Prolonged Isolation”, Case Reports in Obstetrics and Gynecology, vol. 2020, Article ID 8847859, 4 pages, 2020. https://doi.org/10.1155/2020/8847859

Study 268 – 14 cases from China

Further details on 14 cases from Tongi, Wuhan, which have probably been described before (click here or 1-s2.0-S2052297520301049-main). Citation: Gao X, Wang S, Zeng W, Chen S, Wu J, Lin X, Liu Y, Sun Z, Feng L, Clinical and immunological features among COVID-19 affected mother-infant pairs: antibodies to SARS- CoV- 2 detected in breast milk, New Microbes and New Infections,  https://doi.org/10.1016/j.nmni.2020.100752.

Study 267 – Case from Turkey

Mild Covid-19 delivered by Caesarean, both well (click here or ozer pdf_TPD_1941). From Dokuz Eylul University Hospital, Izmir, which has not previously reported cases. Citation: Ozer E, Cagliyan E, Yuzuguldu RI, Cevizci MC, Duman N. Villitis of Unknown Etiology in the Placenta of a Pregnancy Complicated by COVID-19 [published online ahead of print, 2020 Sep 8]. Villitis of Unknown Etiology in the Placenta of a Pregnancy Complicated by COVID-19 [published online ahead of print, 2020 Sep 8]. Turk Patoloji Derg. 2020;10.5146/tjpath.2020.01506. doi:10.5146/tjpath.2020.01506

11 September update – study 266 added

Study 266b – USA, Centres for Disease Control update

The latest CDC tracking data, updated 10th September, shows 20,798 pregnant women with Covid-19 in the United States, of whom 44 (0.21%) have died (click here). Among those for which data were available 205/5,339 (4.7%) were admitted to ICU, and 77/4,674 (1.6%) required mechanical ventialtion. Citation: Centres for Disease Control. Weekly COVID-19 Pregnancy Data updated September 10, 2020, Accessed 11 Sept 2020.

10th September update – studies 264 & 265 added

Study 265b – 71 cases from USA

The authors report 71 women who tested positive for SARS-CoV-2 at delivery, four who had tested positive earlier in the pregnancy and two postnatally (click here or PIIS0301211520305807). One mother with severe disease recovered. Another required ECMO and remains on ventilatory support at a tertiary centre three months following delivery at 30 weeks. All neonates were isolated, and one tested positive but was asymptomatic. No babies died. All authors were affiliated with McGovern Medical School at The University of Texas. Houston but the acknowledgment suggests that the unnamed community hospital was Memorial Hermann Southwest Hospital. There have been no previous reports from Houston. Citation: Pineles BL, Alamo IC, Farooq N, Green J, Blackwell SC, Sibai BM, Parchem JG, Racial-Ethnic Disparities and Pregnancy Outcomes in SARS-CoV-2 Infection in a Universally-Tested Cohort in Houston, Texas, European Journal of Obstetrics & Gynecology & Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.09.012

Study 264b – 246 cases from Spain

246 women with SARS-CoV-2 and 763 control women are reported in this Medxiv preprint (click here or 2020.09.05.20188458v1.full). Five women were admitted to ICU, but none died. Three babies were stillborn. This is the first report from the Spanish “Obs Covid registry” which includes 77 hospitals. The patients are therefore likely to include some from previous Spanish series, namely studies 53, 125, 151, 158, 165, 185, 191, 196, 235, and 266. Note that study 196, authored by the Neo-COVID-19 Research Group, which includes 14 hospitals, reported 42 cases and included one maternal death, so presumably does not completely overlap. Citation: SPANISH OBSTETRIC EMERGENCY GROUP, Oscar Martinez Perez, et al. The association between COVID-19 and preterm delivery: A cohort study with a multivariate analysis. medRxiv 2020.09.05.20188458; doi: https://doi.org/10.1101/2020.09.05.20188458

8 September update – studies 261-263 added

Study 263b – 66 cases (plus one maternal death) from Tehran, Iran

Of 66 women with Covid-19 treated between March 1 to Sep 1, 2020, four were admitted to ICU but none required ventilation (click here or taaa158). Two women aborted, 43 delivered, and 21 pregnancies are ongoing. No baby outcomes are reported directly, although one baby tested positive. No women in the series died. However in the discusssion section it is mentioned that in February 2020, a 22-year-old pregnant woman with COVID-19 at 37 weeks had died in the same hospital. It is not clear if she had been included in studies 23, 66 or 67. The women were cared for in Arash Women’s Hospital, which has also reported a set of triplets of which one was infected with SARS-CoV-2 and survived, and the other two who were negative died, (case 5 in study 250). Those triplets seem not to be included in the present series although it is not clear why. Citation: Pirjani R, Hosseini R, Soori T, et al. Maternal and neonatal outcomes in COVID-19 infected pregnancies: a prospective cohort study [published online ahead of print, 2020 Sep 5]. J Travel Med. 2020;taaa158. doi:10.1093/jtm/taaa158

Study 262b – case report from China

A woman with Covid-19 gave birth normally on Feb 22nd at 38 weeks gestation (click here or Antibodies in the breast milk of a maternal woman with COVID 19). Her baby was isolated and tested negative. IgG and IgA were both detected in breast milk, but no virus. The hospital of birth is unnamed but the mother was later transferred Guanggu Branch of Hubei Maternal and Child Health Hospital, a designated hospital for COVID-19 treatment in Wuhan city. This is not listed on GRID.ac but has reported cases many times. The case has probably been included in studies 8, 17, 30, 38, 54, and 55, and perhaps others. Citation: Yunzhu Dong, Xiangyang Chi, Huang Hai, Liangliang Sun, Mengyao Zhang, Wei-Fen Xie & Wei Chen (2020) Antibodies in the breast milk of a maternal woman with COVID-19, Emerging Microbes & Infections, 9:1, 1467-1469, DOI: 10.1080/22221751.2020.1780952 

Study 261b – Case report from  Saudi Arabia

A woman with mild Covid-19 from Al Ahssa, was delivered by Caesarean at 38 weeks and the baby isolated from the mother (click here or cureus-0012-00000010035). The baby did not become infected although 1/29 health care workers involved contracted SARS-CoV-2. This is the first reported case from this country. Citation: AlOmran A, Almatawah Y, Al Sharit B, Alsadah Z, Mousa O. Infection Prevention and Control Challenges With First Pregnant Woman Diagnosed With COVID-19: A Case Report in Al Ahssa, Saudi Arabia. Cureus. 2020;12(8):e10035. Published 2020 Aug 26. doi:10.7759/cureus.10035

7 September update – studies 258-260 added

Study 260b – Case report from UK

A woman with Covid-19 at 28 weeks recovered and delivered at term (click here or e237007.full). The baby was unaffected. From author affiliations the hospital was part of University Hospitals of Leicester NHS Trust, which runs two maternity hospitals, Leicester Royal Infirmary and Leicester General Hospital. Neither has previously reported cases, although the patient was probably included in the UKOSS report, Study 92. Citation: Anness ASiddiqui F. COVID-19 complicated by hepatic dysfunction in a 28-week pregnant woman. 

Study 259b – Case report from Sweden

A woman with severe Covid-19 and coagulopathy at 32 weeks required Caesarean delivery (click here or s12884-020-03172-8). Mother and baby recovered. The baby tested negative. The hospital was Skåne University Hospital in Malmö which has not previously reported cases. Citation: Ronnje, L., Länsberg, J., Vikhareva, O. et al. Complicated COVID-19 in pregnancy: a case report with severe liver and coagulation dysfunction promptly improved by delivery. BMC Pregnancy Childbirth 20, 511 (2020). https://doi.org/10.1186/s12884-020-03172-8

Study 258b – Case of successful ECMO from France

A woman with Covid 19 required ventilation and Caesarean at 31 weeks. Following delivery her condition worsened and she was treated with ECMO for 7 days (click here or PIIS105307702030793X (002)). She recovered with moderate residual shortness of breath. The baby tested negtive and also recovered. From author affiliations the unnamed ECMO hospital was probably Hôpital Henri-Mondor in Creteil, a southeastern suburb of Paris. The patient may have been previously included in studies 150 & 184. Citation: Fiore A, Piscitelli M, Adodo DK, et al. Successful use of Extracorporeal Membrane Oxygenation (ECMO) in postpartum as rescue therapy in a woman with Covid-19: ECMO postpartum in COVID-19 patient [published online ahead of print, 2020 Aug 6]. J Cardiothorac Vasc Anesth. 2020;doi:10.1053/j.jvca.2020.07.088

3rd September update

Study 257b – Case report from China

A woman with Covid-19 was delivered by Caesarean on February 6, 2020 (click here or main (1)). The baby and other placental/amniotic samples tested negative. Both mother and baby survived. She was cared for in the 5th People’s Hospital of Suzhou grid.490559.4 (click here) which has not previously reported cases. Citation: Lv Y, Gu B, Chen Y, et al. No intrauterine vertical transmission in pregnancy with COVID-19: A case report [published online ahead of print, 2020 Aug 5]. J Infect Chemother. 2020;S1341-321X(20)30266-X. doi:10.1016/j.jiac.2020.07.015

Study 266 – Two cases from Spain

Two pregnant woman with Covid-19 at 12 and 20 weeks respectively had amniocenteis negative for SARS-CoV-2 (click here or 10.1080@14767058.2020.1811669). From author affiliations the unnamed hospital was probably Hospital La Mancha Centro, in Alcazar de San Juan, which has not previously reported cases. Citation: Ana M. Rubio Lorente, Maria Pola Guillén, Nuria López Jimenez, Maria Moreno-Cid Garcia-Suelto, Eduardo Rodriguez Rodriguez & Ana Pascual Pedreño (2020) Study of amniotic fluid in pregnant women infected with SARS-CoV-2 in first and second trimester. Is there evidence of vertical transmission?, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1811669

2nd September update

Study 265 – Pregnant v non-pregnant disease severity using smartphone apps

The authors of this Medxiv preprint (click here or 2020.08.17.20161760v1.full) used a smartphone app (400K women – click here) and the Facebook/Carnegie Mellon COVID-19 survey (1.8M women – click here) to record Covid-19 symptoms and outcomes prospectively. Pregnant women with SARS-CoV-2 infection had the same disease severity as the non-pregnant. Citation: Erika Molteni, Christina M Astley, Wenjie Ma, Carole Helene Sudre, Laura A Magee, Benjamin Murray, Tove Fall, Maria F Gomez, Neli Tsereteli, Paul W Franks, John S Brownstein, Richard Davies, Jonathan Wolf, Timothy Spector, Sebastien Ourselin, Claire Steves, Andrew T Chan, Marc Modat SARS-CoV-2 (COVID-19) infection in pregnant women: characterization of symptoms and syndromes predictive of disease and severity through real-time, remote participatory epidemiology. medRxiv 2020.08.17.20161760; doi: https://doi.org/10.1101/2020.08.17.20161760

1st September update – studies 257 to 264 added

Study 264 – SARS-CoV-2 cell entry gene expression in placenta

Placental expression of the SARS-CoV-2 cell entry genes, ACE2 and TMPRSS2 in pre-pandemic stored samples from the Research Centre for Women’s and Infants’ Health BioBank, and the Lunenfeld-Tanenbaum Research Institute at Mount Sinai Hospital, both in Toronto, Ontario (click here or Bloise AJOG 1-s2.0-S000293782030884X-main). Citation: Bloise E, Zhang J, Nakpu J, Hamada H, Dunk CE, Li S, Imperio GE, Nadeem L, Kibschull M, Lye P, Matthews SG, Lye SJ, Expression of SARS-CoV-2 cell entry genes, ACE2 and TMPRSS2, in the placenta across gestation and at the maternal-fetal interface in pregnancies complicated by preterm birth or preeclampsia, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.08.055.

Study 263 – Case report from The Netherlands

A pregnant woman with Covid-19 developed coagulopathy at 31 weeks, and CTG abnormalities at 32 weeks, necessitating Caesarean birth (click here or Mongula uog.22189). From author affiliations the unnamed hospital was probably Máxima Medical Centre, in Einthoven. Apart from NethOSS reports, the case has not been previously reported. Citation: Mongula, J.E., Frenken, M.W.E., van Lijnschoten, G., Arents, N.L.A., de Wit‐Zuurendonk, L.D., Schimmel‐de Kok, A.P.A., van Runnard Heimel, P.J., Porath, M.M. and Goossens, S.M.T.A. (2020), COVID‐19 during pregnancy: non‐reassuring fetal heart rate, placental pathology and coagulopathy. Ultrasound Obstet Gynecol. Accepted Author Manuscript. doi:10.1002/uog.22189

Study 262 – COVID-19 perinatal biorepository in Massachusetts

100 women and 78 newborns enrolled in the Massachussets General Hospital COVID-19 biorepository (click here or s12874-020-01102-y). No clinical outcomes reported. Citation: Shook, L.L., Shui, J.E., Boatin, A.A. et al. Rapid establishment of a COVID-19 perinatal biorepository: early lessons from the first 100 women enrolled. BMC Med Res Methodol 20, 215 (2020). https://doi.org/10.1186/s12874-020-01102-y

Study 261- Cardiac abnomalities with, but not caused by, SARS-CoV-2. USA

Six babies with congenital heart disease and one with congenital diaphragmatic hernia born to women with SARS-CoV-2, and cared for in the cardiac unit of New York Presbyterian’s Morgan Stanley Children’s Hospital and Columbia University Irving Medical Center (click here or Goldshtrom 2150135120950256). No babies had symptoms and none tested positive. Four babies were inborn, & two transferred in. Some of the pregnancies and births have probably been described elsewhere. Citation: Goldshtrom, N., Vargas, D., Vasquez, A., Kim, F., Desai, K., Turner, M. E., … Krishnamurthy, G. (2020). Neonates With Complex Cardiac Malformation and Congenital Diaphragmatic Hernia Born to SARS-CoV-2 Positive Women—A Single Center Experience. World Journal for Pediatric and Congenital Heart Surgery. https://doi.org/10.1177/2150135120950256

Study 260 – 2 patients from Italy

Two women with positive SARS-CoV-2 serology also had anti SARS-CoV-2 IgG antibodies in their baby’s cord blood (click here or vendola EJOG PIIS0301211520305352). One birth was vaginal and one by Caesarean. From author affilitations the unnamed hospital was probably Ospedale Sant’Andrea in Vercelli in Piedmont, which has not previously reported caes. Both mothers and babies were healthy.  Citation: Vendola Nicoletta, Stampini Viviana, Amadori, Roberta, Gerbino Martina, Curatolo Annalisa, Surico Daniela, et al. Vertical transmission of antibodies in infants born from mothers with positive serology to COVID-19 pneumonia’ European Journal of Obstetrics & Gynecology & Reproductive Biology, Accepted article online.

Study 259 – Test uptake during hospital birth in USA

Of 270 women offered SARS-CoV-2 testing on admission in labour, 13 had symptomatic disease, 3 had tested positive earlier in the pregnancy, and 223 accepted testing. Uptake rose after a range of methods to encourage testing (click here or Kernberg Universal_SARS.97256). Time period May 28th to June 25th No clinical details or test results reported. Barnes Jewish Hospital in St. Louis, Missouri has not previously reported cases. However the case reported in study 69 may have been cared for in the same hospital. Citation: Kernberg A, Kelly J, Nazeer S, et al. Universal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-COV-2) Testing Uptake in the Labor and Delivery Unit: Implications for Health Equity [published online ahead of print, 2020 Aug 26]. Obstet Gynecol. 2020;10.1097/AOG.0000000000004127

Study 258 – Environmental sampling during 4 births in Oregon, USA

A range of samples were collected from the room during two vaginal and two Ceasarean births of asymptomatic women with SARS-CoV-2 (click here or Hermesch SARSCoronavirus_2.97258). No other clinical details. The unnamed university hospital is difficult to identify from author affiliations. Citation: Hermesch, Amy C. MD, PhD; Horve, Patrick F. BS; Edelman, Alison MD, MPH; Dietz, Leslie PhD; Constant, David PhD; Fretz, Mark DDS, MArch; Messer, William B. MD, PhD; Martindale, Robert MD; Van Den Wymelenberg, Kevin PhD Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Environmental Contamination and Childbirth, Obstetrics & Gynecology: August 19, 2020 – Volume Publish Ahead of Print – Issue – doi: 10.1097/AOG.0000000000004112

Study 257 – 6 cases treated with nitric oxide from USA

Six pregnant women with severe Covid-19 were treated with nitric oxide (click here or FAKHR High_Concentrations_of_Nitric_Oxide_Inhalation.97257). Three women delivered four babies, and three pregnancies are ongoing. No mothers or babies died. The patients were treated at Massachusetts General Hospital from April to June 2020, and probably overlap with those reported in studies 142 & 231. Citation: Safaee Fakhr B, Wiegand SB, Pinciroli R, et al. High Concentrations of Nitric Oxide Inhalation Therapy in Pregnant Patients With Severe Coronavirus Disease 2019 (COVID-19) [published online ahead of print, 2020 Aug 26]. Obstet Gynecol. 2020; 10.1097/AOG.0000000000004128. 

21st August update – studies 255 & 256 added

Study 256 – Case report from Norway

In Norweigan. Following from Google translate. A woman with twins developed mild Covid-19 during the process of labour induction at 38 weeks (click here or 59551-fødende-risikopasient-med-covid-19). Both babies were delivered vaginally. She recovered and the twins were healthy. Baby test results not reported. 14 hospital employees were quarantined due to patient contact, but none diagnosed with infection. From author affiliations the unnamed hospital was Sørlandet Hospital, Kristiansand, which has not previously reported cases.  Citation: Ane Cecilie Munk, Linda Reme Sagedal, Turid Stavseth Krogedal, Ida McFadzean, Hanna Oommen. Fødende risikopasient med covid-19 (Maternity risk patient with covid-19) Tidsskrift for Den norske legeforening. Published: July 16, 2020 Issue 11, August 18, 2020 Tidsskr Nor Legeforen 2020 doi: 10.4045 / tidsskr.20.0425

Study 255 – 16 maternal deaths in the UK

Ten women died with SARS-CoV-2 between 01/03/2020 and 31/05/2020, seven directly due to Covid-19, one cause not determined, and two due to unrelated causes (click here or Ref.-201-MBRRACE-UK-maternal-COVID-19-Report-FINAL (002)).  Six further women died by suicide or domestic violence, conceivably related to lockdown, over the same period. They overlap with those in studies 29, 52, 68, 92, 107, 126 & 200. Citation: Knight M, Bunch K, Cairns A, Cantwell R, Cox P, Kenyon S, Kotnis R, Lucas DN, Lucas S, Marshall L, Nelson-Piercy C, Page L, Rodger A, Shakespeare J, Tuffnell D, Kurinczuk JJ on behalf of MBRRACE-UK. Saving Lives, Improving Mothers’ Care Rapid Report: Learning from SARS-CoV-2-related and associated maternal deaths in the UK March – May 2020 Oxford: National Perinatal Epidemiology Unit, University of Oxford 2020.

20 August update – study 254 added

Study 254 – Breast milk testing in 18 affected women from the USA

Eighteen women with SARS-CoV-2, 17 symptomatic, had multiple breast milk samples tested (click here or jama_chambers_2020_ld_200087_1597789061.40481). One sample had detectable SARS-CoV-2 RNA, but no replication-competent virus was detectable in any sample, including the sample that tested positive for viral RNA. The samples were collected from woman anywhere in the United States so may include cases previously reported. Citation: Chambers C, Krogstad P, Bertrand K, et al. Evaluation for SARS-CoV-2 in Breast Milk From 18 Infected Women. JAMA. Published online August 19, 2020. doi:10.1001/jama.2020.15580 [important]

19 August update – Studies 251 to 253 added.

Study 253 – Case report from China

A woman with Covid-19 was delivered at 35 weeks gestation by caesarean section (click here or 1-s2.0-S1876034120304391-main). The baby was not infected. From author affiliations the unnamed hospital was probably Chongqing Three Gorges Central Hospital (grid.477128.f) which has not previously reported cases. Citation: Zhoujie Peng, Jianhui Wang, Yunbo Mo, Wei Duan, Guangjun Xiang, Ming Yi, Lei Bao, Yuan Shi. Unlikely SARS-CoV-2 vertical transmission from mother to child: A case report. Journal of Infection and Public Health, Volume 13, Issue 5, 2020, Pages 818-820, ISSN 1876-0341, https://doi.org/10.1016/j.jiph.2020.04.004.

Study 252a – Case report from Italy

An asymptomatic woman with SARS-CoV-2 underwent Caesarean for breech at 38 weeks gestation (click here or medicina-56-00306-v2). The baby was asymptomatic and tested negative. Swabs from the amniotic surface of the placenta were positive. The hospital was IRCCS Ospedale Policlinico San Martino, Genoa, which has not previously reported cases. Citation: Ferraiolo, A.; Barra, F.; Kratochwila, C.; Paudice, M.; Vellone, V.G.; Godano, E.; Varesano, S.; Noberasco, G.; Ferrero, S.; Arioni, C. Report of Positive Placental Swabs for SARS-CoV-2 in an Asymptomatic Pregnant Woman with COVID-19. Medicina 2020, 56, 306.

Study 252 – 49 new cases from Italy

These 49 women with SARS-CoV-2 in pregnancy were collected between 10–26 April (click here or 10.1080@14767058.2020.1788532).  No outcomes reported. The unnamed hospitals in Milan and the six provinces of Lombardy (Brescia, Como, Lecco, Monza, Pavia, and Sondrio) were probably Sacco (Milan), Mangiagalli (Milan), S. Gerardo MBBM Foundation (Monza), Papa Giovanni XXIII (Bergamo), and San Matteo (Pavia) and the hospitals of Padua, Florence, Lecco, Trento, Modena, Seriate and Piacenza. However the recruitment period was later than that in studies 33, 64 & 117, so these patients have not been previously reported. Citation: Enrico Ferrazzi, Paolo Beretta, Stefano Bianchi, Irene Cetin, Paolo Guarnerio, Anna Locatelli, Anna Maria Marconi, Mario Giuseppe Meroni, Giulia Pavone, Armando Pintucci, Federico Prefumo, Valeria Savasi, Arsenio Spinillo, Beatrice Tassis, Patrizia Vergani, Michele Vignali, Fabio Parazzini & Carlo La Vecchia. (2020): SARS-CoV-2 infection testing at delivery: a clinical and epidemiological priority. Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1788532

Study 251 – 101 cases from USA

Risk factors for 101 pregnant women testing positive for SARS-CoV-2 were compared with 1,317 controls (click here or 1-s2.0-S2589933320301543-main). No outcome data. The women were cared for at Northwestern Memorial Hospital, Chicago March 19 to May 31 2020. They likely include cases in studies 116 & 124Citation: SAKOWICZ A, AYALA AE, UKEJE CC, WITTING CS, GROBMAN WA, MILLER ES, Risk Factors for SARS-CoV2 Infection in Pregnant Women, American Journal of Obstetrics & Gynecology MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100198.

18 August update – belated addition of study 246, ItOSS registry, (HT Aris Papageorghiou), & studies 247 to 250.

Study 250 – 19 infected babies from Iran

19 newborns (incl. one set of triplets) infected with SARS-CoV-2 (click here or 10.1080@14767058.2020.1797672). One mother and four babies died. Dates of birth preceded paper receptin 20 June. The hospitals were Imam Khomeini Hospital, Orumiyeh, West Azerbaijan Province; Shariati Hospital, Tehran (the mother of this case died); Torbat-e Jām Hospital in Torbat-e Jām, Razavi Khorasan Province; Taleghani Hospital in Tehran, Arash Women’s Hospital in Tehran (triplets – 2 died, 1 survived); Boo-Ali Sina Hospital in Sari, Mazandaran Province; Qods Hospital in Qazvin; Ayatollah Mousavi Hospital in Zanjan; Mustafa Khomeini Hospital in Ilam; Allameh Bohluli Hospital in Gonabad, Razavi Khorasan Province; Imam Reza Hospital in Mashhad, Khorasan-e Razavi Province; Imam Sajad Hospital in Shahriar, Tehran Province; Day General Hospital in Tehran; Taleghani Hospital in Gorgan, Golestan Province (baby died); Hakim Jorjani Hospital in Gorgan, Golestan Province (baby died); and Hamedan Besat Hospital in Hamedan. The cases may overlap with those in studies 66, 67 & 218. They probably differ from those reported in studies 23 & 70. Citation: David A. Schwartz, Parisa Mohagheghi, Babak Beigi, Nazanin Zafaranloo, Fereshteh Moshfegh, Anita Yazdani. Spectrum of neonatal COVID-19 in Iran: 19 infants with SARS-CoV-2 perinatal infections with varying test results, clinical findings and outcomes. J Mat Fetal & Neonatal Med 2020, AHEAD-OF-PRINT, 1-10 https://doi.org/10.1080/14767058.2020.1797672

Study 249 – 669 cases with respiratory problems from Brazil

Another report of women with Covid-19 in pregnancy identified through the Brazilian Acute Respiratory Distress Syndrome Surveillance System (click here or oup-accepted-manuscript-2020). Overlap with studies 66, 138, 282, 194, 201, 203 & 248. Citation: Debora de Souza Santos, RN, PhD, Mariane de Oliveira Menezes, CM, MSc, Carla Betina Andreucci, MD, PhD, Marcos Nakamura-Pereira, MD, PhD, Roxana Knobel, MD, PhD, Leila Katz, MD, PhD, Heloisa de Oliveira Salgado, MSc, PhD, Melania Maria Ramos de Amorim, MD, PhD, Maira L S Takemoto, CNM, PhD, Disproportionate impact of COVID-19 among pregnant and postpartum Black Women in Brazil through structural racism lens, Clinical Infectious Diseases, , ciaa1066, https://doi.org/10.1093/cid/ciaa1066

Study 248 – 978 cases with respiratory problems from Brazil

Of 978 pregnant or postpartum women with COVID-19 and Acute Respiratory Distress Syndrome (ARDS), 124 died (click here or 1471-0528.16470). These appear to be the same cases as reported in study 182, albeit in more detail. They probably also overlap with studies 66, 138, 194, 201, & 203. Citation: Takemoto, M.L., Menezes, M.O., Andreucci, C.B., Knobel, R., Sousa, L.A., Katz, L., Fonseca, E.B., Nakamura‐Pereira, M., Magalhães, C.G., Diniz, C.S., Melo, A.S., Amorim, M.M. and Menezes, M.O. (2020), Clinical characteristics and risk factors for mortality in obstetric patients with severe COVID‐19 in Brazil: a surveillance database analysis. BJOG: Int J Obstet Gy. Accepted Author Manuscript. doi:10.1111/1471-0528.16470

Study 247 – 6 placentas from 5 women, Italy

This preprint reports the histology of 6 placentas from 5 pregnancies (one set of twins) complicated by Covid-19 (click here or Placenta in SARS-CoV-2 Bertero). All mothers and babies survived and all babies tested negative. They were cared for in S. Anna Hospital, Turin from March 22, to April 23, 2020, so are probably included in study 246. Citation: Luca Bertero, Fulvio Borella, Giovanni Botta, Andrea Carosso, Stefano Cosma, Marialuisa Bovetti, Marco Carosso, Giancarlo Abbona, Mauro Papotti, Paola Cassoni. Placenta in SARS-CoV-2 infection: a new target for inflammatory and thrombotic events. Research Square. Maternal Fetal Medicine. 2020. DOI: 10.21203/rs.3.rs-30412/v1

Study 246 – 146 cases from Italy (ItOSS)

This Medxiv preprint (not yet published as a peer reviewed paper) reports 146 women with Covid-19 in pregnancy up to April 22nd and collected by the Italian Obstetric Surveillance System, ItOSS (click here or 2020.06.11.20128652v1.full). 142 were positive for SARS-CoV-2 and 4 diagnosed clinically via CXR. Seven mothers were admitted to ITU, and 2 intubated, but none died. Two babies were stillborn and five tested positive. There were no neonatal deaths. These patients likely overlap with those in studies 32, 64, 76, 79, 109, 114, 188 and 197. They probably do not overlap with those in study 195. Citation: Alice Maraschini, Edoardo Corsi, Michele Antonio Salvatore, Serena Donati. Coronavirus and birth in Italy: results of a national population-based cohort study. medRxiv 2020.06.11.20128652; doi: https://doi.org/10.1101/2020.06.11.20128652 For published version click here or ANN_20_03_17. Citation: Maraschini A, Corsi E, Salvatore MA, Donati S; ItOSS COVID-19 Working Group. Coronavirus and birth in Italy: results of a national population-based cohort study. Ann Ist Super Sanita. 2020 Jul-Sep;56(3):378-389. doi: 10.4415/ANN_20_03_17. PMID: 32959805.

17th August update – studies 238 to 245 added

Study 245 – 141 cases from India

Out of 141 women with Covid-19 in pregnancy there were 3 abortions, one ectopic pregnancy and 3 maternal deaths (click here or Nayak 13224_2020_Article_1335). There were 3 stillbirths and 3 babies tested positive. From the description and author affiliations, the unnamed hospital is almost certainly Lokmanya Tilak Municipal General Hospital, grid.415652.1, Mumbai, which has not previously reported cases. Citation: Nayak, A.H., Kapote, D.S., Fonseca, M. et al. Impact of the Coronavirus Infection in Pregnancy: A Preliminary Study of 141 Patients. J Obstet Gynecol India 70, 256–261 (2020). https://doi.org/10.1007/s13224-020-01335-3

Study 244 – 125 cases from Turkey

Of 125 pregnant women with Covid-19 (click here or Oncel2020_Article), 7 mothers required ventilation and 5 died. Four babies tested positive and one (who tested negative) died. The babies were cared for in 34 unnamed neonatal intensive care units. From author affiliations these probably include İzmir (3 centres), İstanbul (6 centres), Rize (1 centre), Ankara (4 centres) and Kocaeli (1 centre). Some of these cases probably overlap with those reported in studies 31, 145, 146, 203, 210 & 223. Citation: Oncel, M.Y., Akın, I.M., Kanburoglu, M.K. et al. A multicenter study on epidemiological and clinical characteristics of 125 newborns born to women infected with COVID-19 by Turkish Neonatal Society. Eur J Pediatr (2020). https://doi.org/10.1007/s00431-020-03767-5

Studies 238 to 243 – 6 case reports, from Portugal, France, US, India, UK & Nigeria

S 238 (facial palsy) from Porto, Portugal (click here or figuerdo), Citation: Figueiredo R, Falcão V, Pinto MJ, et al. BMJ Case Rep 2020;13:e237146. doi:10.1136/bcr-2020-237146S 239 (severe case) from Paris (click here or federici). Citation: Federici L, Picone O, Dreyfuss D, et al. BMJ Case Rep 2020;13:e237511. doi:10.1136/bcr-2020-237511S 240 (serial cord antibody levels) from Mount Sinai, New York (click here or Toner). Citation: Toner et al. Passive Immunity in COVID Positive Pregnant Patient. Am J Perinatol. 21 July 2020. https://doi.org/10.1055/s-0040-1715643. &nbsp;S 241 (mild case) from New Delhi, (click here or Chhabra IndianJAnaesth6414141-6060246_165002). Citation: Chhabra A, Rao TN, Kumar M, Singh Y, Subramaniam R. Anaesthetic management of a COVID‑19 parturient for caesarean section ‑ Case report and lessons learnt. Indian J Anaesth 2020;64:S141-3. S 242 (HELLP) from Birmingham, UK (click here or Ahmed e237521.full) Citation: Ahmed I, Eltaweel N, Antoun L, et al. BMJ Case Rep 2020;13:e237521. doi:10.1136/bcr-2020-237521.  S 243 (Caesarean) from Lagos (click here or Makwe). Citation: Christian Chigozie Makwe et al. Caesarean delivery of first prediagnosed COVID-19 pregnancy in Nigeria. Pan African Medical Journal. 2020;36:100. [doi: 10.11604/pamj.2020.36.100.23892]

13 August update – studies 236 & 237 added

Study 237 – Effect of lockdown on hospital births in Nepal

Birth numbers halved, stillbirths increased by 50% and neonatal mortality nearly fourfold, during lockdown in nine Nepal hospitals (click here PIIS2214109X20303454). No women or babies were tested for Covid-19. Citation: Ashish KC, Rejina Gurung, Mary V Kinney, Avinash K Sunny, Md Moinuddin, Omkar Basnet, Prajwal Paudel, Pratiksha Bhattarai, Kalpana Subedi, Mahendra Prasad Shrestha, Joy E Lawn, Mats Målqvist. Effect of the COVID-19 pandemic response on intrapartum care, stillbirth, and neonatal mortality outcomes in Nepal: a prospective observational study. Lancet Global Health. August 10, 2020 DOI: https://doi.org/10.1016/S2214-109X(20)30345-4 [important]

Study 236 – 45 cases from USA

45 babies were born to SARS-CoV-2 positive mothers, 30 were vaginal births, 33 co-located with their mothers and 31 were breast fed (click here or s41372-020-0765-30). 27 of the mothers were asymptomatic. No other maternal details were reported. All 45 newborns were tested & 3 were positive. The patients were cared for at Elmhurst Hospital Center in New York which has not previously reported cases.  Citation: Patil, U.P., Maru, S., Krishnan, P. et al. Newborns of COVID-19 mothers: short-term outcomes of colocating and breastfeeding from the pandemic’s epicenter. J Perinatol (2020). https://doi.org/10.1038/s41372-020-0765-3

11 August update – study 235 added

Study 235 – 125 anti-SARS-CoV-2 sero-positive women from Spain

Of 874 pregnant women attending first trimester screening (n=372) or delivery (n=502) from April 14 to May 5, 2020, 125 were positive for anti-SARS-CoV-2 IgG, IgM, or IgA. 54/372 in first trimester, and 71/502 in 3rd trimester (click here or PIIS0140673620317141 & supplementary material mmc1). Three women required oxygen therapy, but none critical care. No baby outcomes reported. Women were cared for in Hospital Sant Joan de Déu, Hospital Clínic, and Sant Pau all in Barcelona. They probably overlap with cases reported in studies 185 and 191, but probably not with those in studies 53, 125, 151, 158, 165, or 196. Citation: Francesca Crovetto, Fàtima Crispi, Elisa Llurba, Francesc Figueras, María Dolores Gómez-Roig, Eduard Gratacós. Seroprevalence and presentation of SARS-CoV-2 in pregnancy.  Lancet. Published Online August 6, 2020 https://doi.org/10.1016/S0140-6736(20)31714-1

10 August update – study 234 added

Study 234 – 70 cases from US

Of 675 pregnant women admitted for delivery and tested for SARS-CoV-2, 70 were positive, of whom 55 were asymptomatic on presentation (click here or 1471-0528.16403). Three mothers were hypoxic, one was admitted to ITU but none required ventilation. No mothers died. There was one stillbirth to a mother with asymptomatic Covid-19 and other pathology. 73 babies were born, 71 were tested and all were negative. The three hospitals, were Weill Cornell Medical Center, Queens, and Lower Manhattan Hospital. The cases may therefore also have been included in studies 160, 216 and 230. However, they were probably not included in the other NY Presbyterian series namely studies 14, 27, 41, 95, 96 and 136. Citation: Prabhu, M., Cagino, K., Matthews, K.C., Friedlander, R.L., Glynn, S.M., Kubiak, J.M., Yang, Y.J., Zhao, Z., Baergen, R.N., DiPace, J.I., Razavi, A.S., Skupski, D.W., Snyder, J.R., Singh, H.K., Kalish, R.B., Oxford, C.M. and Riley, L.E. (2020), Pregnancy and postpartum outcomes in a universally tested population for SARS‐CoV‐2 in New York City: A prospective cohort study. BJOG: Int J Obstet Gy. Accepted Author Manuscript. doi:10.1111/1471-0528.16403

9 August update – studies 230 to 233 added

Study 233 – case report from Morocco

A woman contracted Covid-19 at 31 weeks gestation, required oxygen therapy and went into premature labour. A Caesarean was performed for fetal distress (click here or 8852816). The mother recovered. The baby tested negative but had severe birth asphyxia and died age 5 days. The mother was cared for at University Hospital of Mohammed VI, Marrakech, which has not previously reported cases. This is the first report from Morocco. Citation: Yassamine Abourida, Houssam Rebahi, Imane Oussayeh, Hajar Chichou, Bouchra Fakhir, Abderraouf Soummani, Hicham Jalal, Fatiha Bennaoui, Nadia El Idrissi Slitine, Fadl Mrabih Rabou Maoulainine, Ahmed Rhassane El Adib, and Mohamed Abdenacer Samkaoui. Management of Severe COVID-19 in Pregnancy. Case Reports in Obstetrics and Gynecology Volume 2020, Article ID 8852816, 5 pages https://doi.org/10.1155/2020/8852816

Study 232 – 44 cases from US

Of 44 pregnant or recently postpartum women with COVID-19, 5 had severe disease and 2 required ventilation (click here or ijgo.13333). All mothers survived. Of 11 babies born, 9 tested negative and 2 declined testing. All survived. 31 pregnancies are ongoing. The majority of patients belonged to racial [sic] or ethnic minority groups. From author affiliations the unnamed hospital was probably Brigham and Women’s Hospital, Boston. Some cases may therefore have been reported in study 231, but probably differ from those in studies 129 & 142. Citation: Onwuzurike, C., Diouf, K., Meadows, A.R. and Nour, N.M. (2020), Racial and ethnic disparities in severity of COVID‐19 disease in pregnancy in the United States. Int J Gynecol Obstet. Accepted Author Manuscript. doi:10.1002/ijgo.13333

Study 231 – 19 placentas from USA

2/19 placentas of affected pregnancies tested positive for SARS-CoV-2 by in-situ hybrization (click here or s41379-020-0639-4). There were no specific pathologic features compared with 262 control placentas. One fetus was stillborn at 22 weeks and not tested. There were two sets of twins. All liveborn babies survived, and only one tested positive. From the case codes in Table 2 it appears that 10 pregnancies had been cared for at Massachusetts General Hospital, 4 at Brigham and Women’s Hospital & 5 at Beth Israel Deaconess Medical Center, Boston. Some have therefore probably been reported in studies 129 & 142Citation: Hecht, J.L., Quade, B., Deshpande, V. et al. SARS-CoV-2 can infect the placenta and is not associated with specific placental histopathology: a series of 19 placentas from COVID-19-positive mothers. Mod Pathol (2020). https://doi.org/10.1038/s41379-020-0639-4

Study 230 – Placental features of 74 cases from USA

2/53 placentas from affected pregnancies contained a SARS-CoV-2 viral signal by in-situ hybridization (click here or Zhang, Placenta, AJOGMFM). One baby tested positive, the other negative. Both were asymptomatic. There were no specific histological differences between 74 placentas from SARS-CoV-2 positive pregnancies and 290 controls. The authors are affiliated with the New York Presbyterian, Brooklyn Methodist, Weill Cornell group of hospitals so the clinical aspects of the cases have probably been reported before.  Citation: Zhang P, Heyman T, Salafia C, Dygulska B, Lederman S, Detection of SARS-CoV-2 in placentas with pathology and vertical transmission, American Journal of Obstetrics & Gynecology MFM (2020), doi:  https://doi.org/10.1016/j.ajogmf.2020.100197.

8 August update – studies 225 to 229 added

Study 229 – Some assisted reproduction pregnancies during the pandemic in France.

The authors report 88, or possibly 104, women (numbers are unclear) who conceived by assisted reproduction between December 2019 & March 2020, and were still pregnant after the first reported case of Covid-19 in France on 12th February. Ten had symptoms related to Covid-19, none severe or requiring intensive care (click here or PIIS0301211520304929). Five of the ten were tested and two were positive. 15 women miscarried although their Covid-19 status was not reported. From author affiliations the unnamed centre was probably the Reproductive Biology UnitAntoine Béclère Hospital, Clamart. These cases may therefore feature in studies 150, 157, 184 & 217. The pregnancies were unlikely to have been sufficiently far advanced to have featured in studies 48 & 187. Citation: Mayeur A, Binois O, Gallot V, Hesters L, Benoit A, Oppenheimer A, Presse M, Zeghari F, Benguigi J, Grynberg M, Frydman N, Sonigo C, First follow-up of art pregnancies in the context of the COVID-19 outbreak, European Journal of Obstetrics & Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.07.050

Study 228 – case report from USA

A pregnant woman contracted severe Covid-19 requiring ventilation at 32 weeks (click here or Ching Case Rep RespMed). She was delivered by Caesarean section for suspected placenta praevia and recovered. The baby required intubation and ventilation for 48 hours but tested negative. The ultimate baby outcome is not reported. The hospital is unnamed but the authors’ affiliation with San Joaquin Critical Care Medical Group, suggests that it was San Joaquin General Hospital in Stockton, California which has not previously reported cases. Citation: Josebelo Chong, Siraj Ahmed, Kyle Hill. Acute Respiratory Distress Syndrome in a pregnant patient with COVID-19 improved after delivery: A case report and brief review. Respiratory Medicine Case Reports. Volume 31, 2020, 101171, ISSN 2213-0071, https://doi.org/10.1016/j.rmcr.2020.101171.

Study 227 – case report from USA

A woman with mild Covid-19 gave birth to a male infant vaginally at term (click here or HSU jmv.26386). She recovered. The baby breast fed, tested negative and was fine. The virus was demonstrated in the placenta by immuno-histochemistry using a  SARS-CoV-2 nucleocapsid-specific monoclonal antibody. Mother and baby were cared for at University of Missouri Women and Children’s Hospital Columbia, Missouri, which has not previously reported cases. The clinical details of case 69 differ. Citation: Hsu, A.L., Guan, M., Johannesen, E., Stephens, A.J., Khaleel, N., Kagan, N., Tuhlei, B.C. and Wan, X.‐F. (2020), Placental SARS‐CoV‐2 in a Pregnant Woman with Mild COVID‐19 Disease. J Med Virol. Accepted Author Manuscript. doi:10.1002/jmv.26386

Study 226 – 3 cases treated with remdesivir from USA

Three pregnant women with Covid-19 were treated with remdesivir outside a clinical trial (click here or PIIS0002937820308292). One developed “transaminitis” – I think the authors mean raised liver transaminase. The pre-print is missing a table – which the authors attributed to the remdesivir. That woman later developed intrahepatic cholestasis of pregnancy and delivered normally. The other pregnancies are ongoing. The acknowledgements suggest that the unnamed hospital is Lucile Packard Children’s Hospital at Stanford, California. Although one author is shared with study 115 from another unnamed Stanford hospital, the clinical details differ. These cases have probably not previously been reported. Citation: Igbinosa I, Miller S, Bianco K, Nelson J, Kappagoda S, Blackburn BG, Grant P, Subramanian A, Lyell D, El-Sayed Y, Aziz N, Use of Remdesivir for Pregnant Patients with Severe Novel 2019 Coronavirus Disease, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.08.001.

Study 225 – over 600 cases (412 births) in India

Nair hospital, Mumbai, a dedicated Covid-19 facility, has cared for over 600 pregnant women with the disease (click here or ijgo.13338). There have been 412 births including seven pairs of twins and one set of triplets. No mothers died of Covid-19 directly, although four died of other causes. No baby outcomes reported. The first two cases had originally been cared for elsewhere, and also previously denied admission at four private hospitals, the latter a feature of news reports from India (click here). Two health care workers contracted COVID-19. Nair Hospital has not previously reported cases. The case reported in study 58 was from New Delhi. Citation: Mahajan, N.N., Pednekar, R., Patil, S.R., Subramanyam, A.A., Rathi, S., Malik, S., Mohite, S.C., Shinde, G., Joshi, M., Kumbhar, P., Tilve, A., Lokhande, P.D. and Srivastava, S.A. (2020), Preparedness, administrative challenges for establishing obstetric services, and experience of delivering over 400 women at a tertiary care COVID‐19 hospital in India. Int J Gynecol Obstet. Accepted Author Manuscript. doi:10.1002/ijgo.13338 [important]

31 July update – studies 221 to 224 added

Study 224 – 6 cases from Sri lanka

This paper primarily reports the mental health of pregnant women without Covid-19 during the pandemic in Sri Lanka (click here or ijgo.13335). The authors mention six cases of COVID-19 positive pregnant women in the country. Although no further details are given, and the link given (ref 8) to the Live Situational Analysis Dashboard of Sri Lanka (click here) does not cite pregnancy cases, this is the first scientific report of Covid-19 in pregnancy from Sri Lanka. Citation: Patabendige, M., Gamage, M.M., Weerasinghe, M. and Jayawardane, A. (2020), Psychological impact of the COVID‐19 pandemic among pregnant women in Sri Lanka. Int J Gynecol Obstet. Accepted Author Manuscript. doi:10.1002/ijgo.13335

Study 223 – 3 cases from Turkey

Three pregnant women tested postive for SARS-CoV-2 in Ankara City Hospital (click here or PIIS0301211520304930). All three had co-morbidities but mild disease and were delivered by Caesarean. Baby outcomes not reported. Citation: Tanacan A, Erol SA, Turgay B, Anuk AT, Secen EI, Yegin GF, Ozyer S, Kirca F, Dinc B, Unlu S, Yapar Eyi EG, Keskin HL, Sahin D, Surel AA, Tekin OM, The Rate of SARS-CoV-2 Positivity in Asymptomatic Pregnant Women Admitted to Hospital for Delivery: Experience of A Pandemic Center in Turkey, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.07.051

Study 222 – Case report from USA

A 22-year-old woman with placenta previa and a past medical history of tuberous sclerosis and multiple associated comorbidities contracted Covid-19 at 23 weeks + 6 days gestation (click here or 2324709620946621). She required intubation and ventilation and was delivered by caesarean at 25+5. The baby tested negative. Both mother and baby survived. The hospital is unnamed but from author affiliations is probably Los Angeles County+USC Medical Center, California,which has not previously reported cases. Citation: Easterlin, M. C., De Beritto, T., Yeh, A. M., Wertheimer, F. B., & Ramanathan, R. (2020). Extremely Preterm Infant Born to a Mother With Severe COVID-19 Pneumonia. Journal of Investigative Medicine High Impact Case Reports. https://doi.org/10.1177/2324709620946621

Study 221 – SARS-CoV-2 serological testing of 1,293 parturient women, USA

1,293 parturient women tested for SARS-CoV-2 antibodies in two hospitals in Philadelphia, 80 were positive (click here or eabd5709.full), Percentages in results table 1 are given by row rather than column making comparisons difficult. The hospitals are unnamed. A preprint of this paper in MedXiv was study 202. Citation: D. D. Flannery et al., Sci. Immunol. 10.1126/sciimmunol.abd5709 (2020)

30 July update – study 220 added

Study 220 – 29 cases from China

29 women with Covid-19 between January 30 and March 10, 2020, gave birth to 30 neonates (1 set of twins) (click here or journal.pmed.1003195). The hospitals were Renmin Hospital, Wuhan University, and Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology. These cases have surely been published before. Citation: Wu Y-T, Liu J, Xu J-J, Chen Y-F, Yang W, Chen Y, et al. (2020) Neonatal outcome in 29 pregnant women with COVID-19: A retrospective study in Wuhan, China. PLoS Med 17(7): e1003195. https://doi.org/10.1371/journal.pmed.1003195

28 July update – studies 217 to 219 added

Study 219 – 3 cases from New Jersey, USA

Three women with Covid-19 in pregnancy required ventilation and delivery by Caesarean (click here or Douedi AM J Cas Rep NJ). All three mothers and babies survived, and all babies tested negative. The hospital is unnamed, but from author affiliations is probably Jersey Shore University Medical Center. The cases were probably therefore also reported in study 149. Citation: Steven Douedi, Asseel Albayati, Nasam Alfraji, Usman Mazahir, Eric Costanzo Steven Douedi, Asseel Albayati, Nasam Alfraji, Usman Mazahir, Eric Costanzo. Am J Case Rep 2020; 21:e925513 DOI: 10.12659/AJCR.925513

Study 218 – Case report from Iran

A 30 year old woman contracted Covid-19 at 21 weeks gestion (click here or Soleimani JMFM). She received methyprednisolone, Lopinivir, Azithromycin, Hydrocortisone and immune plasma and survived. The pregnancy is ongoing. The hospital is unnamed and only identifiable as being in Tehran from author affiliations. The case in study 101 was from a different city, and the details differ from those of the two survivors is study 67. Citation: Zahra Soleimani & Azam Soleimani (2020): ADRS due to COVID-19 in midterm pregnancy: successful management with plasma transfusion and corticosteroids, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1797669

Study 217 – 83 cases from France & Belgium

83 pregnant women with Covid-19 were compared with a group of non-pregnant affected control women (click here or Badr AJOG PIIS0002937820307766). No raw data and no pregnancy outcomes provided. The hospitals were Antoine Béclère, Clamart, Paris, Bicêtre Hospital, Le Kremlin-Bicêtre, Centre Hospitalier Sud Francilien, Corbeil-Essones, and University Hospital Brugmann, Brussels. These cases have probably been already reported. Citation: Badr DA, Mattern J, Carlin A, Cordier A-G, Maillart E, El Hachem L, El Kenz H, Andronikof M, De Bels D, Damoisel C, Preseau T, Vignes D, Cannie MM, Vauloup-Fellous C, Fils J-F, Benachi A, Jani JC, Vivanti AJ, Are clinical outcomes worse for pregnant women ≥ 20 weeks’ gestation infected with COVID-19? A multicenter case-control study with propensity score matching, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.07.045.

27 July update – study 216 added

Study 216 – 120 babies born to SARS-CoV-2 positive mothers from USA

120 neonates born to 116 mothers who had tested positive for SARS-CoV-2 in pregnancy, were were tested at 24 hours of life. Of them, 79 were also tested at 5-7 days, and 72 at 14 days. All tested negative at all time points and none had symptoms of COVID-19 (click here or  1-s2.0-S2352464220302352-main). From author affiliations they were probably cared for at Weill Cornell Presbyterian Komansky, Presbyterian Queens, and Presbyterian Lower Manhattan hospitals all in New York. Citation: Christine M Salvatore, Jin-Young Han, Karen P Acker, Priyanka Tiwari, Jenny Jin, Michael Brandler, Carla Cangemi, Laurie Gordon, Aimee Parow, Jennifer DiPace, Patricia DeLaMora. Neonatal management and outcomes during the COVID-19 pandemic: an observation cohort study, The Lancet Child & Adolescent Health, 2020, ISSN 2352-4642, https://doi.org/10.1016/S2352-4642(20)30235-2.

25 July update – studies 212 to 215 added

Study 215 – Case report from USA

A woman with Covid-19 in pregnancy continued to test positive for SARS-CoV-2 for 100 days (click here or Prolonged_Detection_of_Severe_Acute_Respiratory.97292). Mother and baby survived. All viral tests on baby, placenta and breast milk were negative. The cord blood was positive for IgG antibodies to SARS-CoV-2. From author affiliations the hospital was MultiCare Tacoma General Hospital, Tacoma, Washington State, which has not previously reported cases. Citation: Molina, Loren P. MD; Chow, Siu-Kei PhD; Nickel, Adam DO; Love, Jason E. MD Prolonged Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) RNA in an Obstetric Patient With Antibody Seroconversion, Obstetrics & Gynecology: July 21, 2020 – Volume Publish Ahead of Print – Issue – doi: 10.1097/AOG.0000000000004086

Study 214 – 100 cases from USA

The authors report the Race [sic] and Ethnicity of 100 cases of Covid-19 in pregnancy from New York (click here or Influence_of_Race_and_Ethnicity_on_Severe_Acute.97290). These cases have likely been reported before. Citation: Emeruwa, Ukachi N. MD, MPH; Spiegelman, Jessica MD; Ona, Samsiya MD; Kahe, Ka MD, ScD; Miller, Russell S. MD; Fuchs, Karin M. MD, MHA; Aubey, Janice J. MD, MPH; Booker, Whitney MD; D’Alton, Mary E. MD; Friedman, Alexander M. MD, MPH; Aziz, Aleha MD, MPH; Sutton, Desmond MD; Purisch, Stephanie E. MD; Goffman, Dena MD; Melamed, Alexander MD, MPH; Gyamfi-Bannerman, Cynthia MD, MSc Influence of Race and Ethnicity on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Rates and Clinical Outcomes in Pregnancy, Obstetrics & Gynecology: July 21, 2020 – Volume Publish Ahead of Print – Issue – doi: 10.1097/AOG.0000000000004088

Study 213 – 89 cases from Brazil

Of 89 women with Covid-19 cared for in a single institution between March 12 & May 25, 2020, the details of five who experienced a fetal death are reported (click here or 1-s2.0-S2214911220300734-main). No details of the other cases, and no explicit maternal outcomes are reported, but enough details are given for it to be implied that the mothers survived. From author affiliations the unnamed hospital is probably Hospital e Maternidade Santa Joana, São Paulo. Apart from study 194 which was from a different city, all previous reports of Covid-19 in pregnancy from Brazil (studies 66, 138, 182 & 201) have been of maternal deaths. These cases have therefore probably not previously been reported. Citation: Rosana Richtmann, Maria Regina Torloni, Andre Ricardo Oyamada Otani, Jose Eduardo Levi, Mariana Crema Tobara, Camila de Almeida Silva, Lívio Dias, Lisia Miglioli-Galvão, Pollyanna Martins Silva, Mario Macoto Kondo, Fetal deaths in pregnancies with SARS-CoV-2 infection in Brazil: A case series, Case Reports in Women’s Health,  Volume 27, 2020, e00243, ISSN 2214-9112,
https://doi.org/10.1016/j.crwh.2020.e00243.

Study 212 – 2 cases from China

There were only two pregnant women with Covid-19 in Yichang city between January 20 & April 9, 2020 (click here or Coronavirus_disease_2019__COVID_19__in_pregnancy_.126). Both mothers and both babies survived. Neither baby was infected. The hospital was Yichang Central People’s Hospital. On GRID.ac this disambiguates as Peking University People’s Hospital grid.411634.5 which is probably an error. Yichang city is in Western Hubei province about 200 km west of Wuhan, and about 1000 km south of Peking/Beijing. Yichang city was a centre in study 57, so these two cases were probably included in that series, Citation: Zheng, Tingting; Guo, Jianqiang; He, Wencong; Wang, Hao; Yu, Huiling; Ye, Hong. Coronavirus disease 2019 (COVID-19) in pregnancy: 2 case reports on maternal and neonatal outcomes in Yichang city, Hubei Province, China, Medicine: July 17, 2020 – Volume 99 – Issue 29 – p e21334 doi: 10.1097/MD.0000000000021334

24 July update – studies 208 to 211 added

Study 211 – 21 cases from China

21 term pregnancies with Covid-19 (click here or Chen-Bai2020_Article_MaternalAndInfantOutcomesOfFul). No mothers or babies died. All babies tested negative. The patients were cared for in Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology. They probably overlap with those in studies 2, 8, 11, 15, 39, 55, 57, 59, 73, and 108Citation: Chen, Y., Bai, J. Maternal and infant outcomes of full-term pregnancy combined with COVID-2019 in Wuhan, China: retrospective case series. Arch Gynecol Obstet (2020). https://doi.org/10.1007/s00404-020-05573-8

Study 210 – 23 cases from Turkey

23/296 pregnant women tested positive for SARS-CoV-2 infection during one month’s screening from 27 April, in a “Coronavirus Pandemic Hospital” in Istanbul (click here or 10.1080@14767058.2020.1798398). Another 15 referral cases were treated over the same period. No pregnancy outcomes were reported. From author affiliations the unnamed hospital is probably Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital. If so, these cases probably include those reported in study 146. Citation: Murat Yassa, Cihangir Yirmibes, Gul Cavusoglu, Hazal Eksi, Cevdet Dogu, Canberk Usta, Memis Ali Mutlu, Pinar Birol, Cagri Gulumser & Niyazi Tug. (2020). Outcomes of universal SARS-CoV-2 testing program in pregnant women admitted to hospital and the adjuvant role of lung ultrasound in screening: A prospective cohort study. The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1798398

Study 209 – 51 placentas from infected pregnancies in New York, USA

All 51 placentas from SARS-CoV-2 affected pregnancies were negative for SARS-Cov-2 by in situ hybridization and immunohistochemistry (click here or his.14215), Citation: Smithgall, M.C., Liu‐Jarin, X., Hamele‐Bena, D., Cimic, A., Mourad, M., Debelenko, L. and Chen, X. (2020), Third Trimester Placentas of SARS‐CoV‐2‐Positive Women: Histomorphology, including Viral Immunohistochemistry and in Situ Hybridization. Histopathology. Accepted Author Manuscript. doi:10.1111/his.14215

Study 208 – Ten cases from Portugal

Ten pregnant women with Covid-19 were cared for at Centro Hospitalar Universitario, Sao Joao, Porto (click here or Perinatal management of SARS CoV 2 infection in a level III University Hospital). One women was admitted to intensive care but all mothers and babies survived. No babies tested positive. This hospital has not previously reported cases. Citation: Susana Pissarra, Marta Rosário, Marina Moucho & Henrique Soares (2020) Perinatal management of SARS-CoV-2 infection in a level III University Hospital, The Journal of Maternal-Fetal & Neonatal Medicine. DOI: 10.1080/14767058.2020.1786526

2 July update – studies 205 to 207 added

Study 207 – Mental health of 14 cases from London, UK

Fourteen women with Covid-19 in pregnancy recorded their levels of anxiety & depression (click here or PIIS0301211520304796). No clinical outcomes reported. The hospital is not named but the authors note that this is an extension of the series in study 206 so must be North Middlesex. The patients are therefore also included in study 93. Citation: Kotabagi P, Nauta M, Fortune L, Yoong W, COVID-19 positive mothers are not more anxious or depressed than non COVID pregnant women during the pandemic: a pilot case-control comparison. European Journal of Obstetrics and Gynecology and Reproductive Biology (2020). doi: https://doi.org/10.1016/j.ejogrb.2020.07.037

Study 206 – Mental health of 11 cases from London, UK

Eleven women with Covid-19 in pregnancy recorded their levels of anxiety & depression (click here or aogs.13928). No clinical outcomes reported. The authors note that these patients were treated at North Middlesex Hospital and included those in study 93. Citation: Kotabagi, P., Fortune, L., Essien, S., Nauta, M. and Yoong, W. (2020), Anxiety and depression levels among pregnant women with COVID‐19. Acta Obstet Gynecol Scand, 99: 953-954. doi:10.1111/aogs.13928

Study 205 – 91 cases from Madrid, Spain

Of 91 pregnant women with Covid-19 treated in Hospital Universitario “12 de Octubre”, 4 required ventilation, but none died (click here or 10.1080@14767058.2020.1793320). 38 babies delivered, all testing negative immediately after birth, although one developed mild Covid-19 and tested positive at 6 days. These cases likely overlap with those in studies 151, 165 & 196. Citation: Patricia Barbero, Laura Mugüerza, Ignacio Herraiz, Antonio García Burguillo, Rafael San Juan, Laura Forcén, Inmaculada Mejía, Emma Batllori, María Dolores Montañez, Paloma Vallejo, Olga Villar, Diana García Alcazar & Alberto Galindo (2020) SARS-CoV-2 in pregnancy: characteristics and outcomes of hospitalized and non-hospitalized women due to COVID-19. The Journal of Maternal-Fetal & Neonatal Medicine. DOI: 10.1080/14767058.2020.1793320

21 July update – study 204 added

Study 204 – 7 screen positives from UK

Seven pregnant women tested positive for SARS-CoV-2 out of 189 screened over a two week period 22nd April to 5th May, 2020 at Newham University Hospital in East London (click here or PIIS0301211520304772). Only one was symptomatic. No outcomes reported. Citation: Abeysuriya S, Wasif S, Counihan C, Shah N, Iliodromiti S, Cutino-Moguel M-Teresa, Saeed F, Velauthar L, Universal Screening for SARS-CoV-2 in Pregnant Women at Term Admitted to an East London Maternity Unit, European Journal of Obstetrics & Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.07.035

19 July update – study 203 added.

Study 203 – 37 cases from Turkey

Of 100 pregnant women with possible Covid-19, 29 had the diagnosis confirmed by RT‐PCR, and a further eight were clinically high suspicious (click here or ijgo.13318). None died or were admitted to ITU. No babies died or tested positive. Patients were cared for at the Ministry of Health Ankara City Hospital which has not previously reported cases. The only previous Ankara case (study 31) was from a different hospital and the clinical details differ. Citation: Sahin, D., Tanacan, A., Erol, S.A., Anuk, A.T., Eyi, E.G., Ozgu‐ Erdinc, A.S., Yucel, A., Keskin, H.L., Tayman, C., Unlu, S., Kirca, F., Dinc, B., San, I., Parpucu, Ü.M., Surel, A.A. and Moraloglu, O.T. (2020). A pandemic center’s experience of managing pregnant women with COVID‐19 infection in Turkey: A prospective cohort study. Int J Gynecol Obstet. Accepted Author Manuscript. doi:10.1002/ijgo.13318 

18 July update – studies 198 to 202 added

Study 202 – 80 cases from Pennsylvania, USA

This preprint from reports 80 pregnant women who tested positive for IgG and/or IgM SARS-CoV-2-specific antibodies in two centers in Philadelphia (click here or Flannery 2020.07.08.20149179v1.full).  46 of the 72 who were tested also had a SARS-CoV-2 positive PCR result. 79 women delivered a liveborn infant. The outcome of the 80th woman was not reported. The hospitals are not named. The cases may overlap with studies 65 & 175 and possibly also with study 86.  Citation:Dustin D. Flannery, Sigrid Gouma, Miren B. Dhudasia, Sagori Mukhopadhyay, Madeline R. Pfeifer, Emily C. Woodford, Jeffrey S. Gerber, Claudia P. Arevalo, Marcus J. Bolton, Madison E. Weirick, Eileen C. Goodwin, Elizabeth M. Anderson, Allison R. Greenplate, Justin Kim, Nicholas Han, Ajinkya Pattekar, Jeanette Dougherty, Olivia Kuthuru, Divij Mathew, Amy. Baxter, Laura. Vella, JoEllen Weaver, Anurag Verma, Rita Leite, Jeffrey S. Morris, Daniel J. Rader, Michal A. Elovitz, E. John Wherry, Karen M. Puopolo, Scott E. Hensley. SARS-CoV-2 Seroprevalence Among Parturient Women medRxiv 2020.07.08.20149179; doi: https://doi.org/10.1101/2020.07.08.20149179

Study 201 – 20 maternal deaths from Brazil

Twenty COVID-19 related maternal deaths were identified from the Brazilian Ministry of Health surveillance system (click here or Takemoto Maternal mortality and COVID 19). Ten were in the Northeast region, and nine in the Southeast (5 in São Paulo). They probably overlap with those in studies 138, 182 & 194Citation: Maira L. S. Takemoto , Mariane O. Menezes , Carla B. Andreucci , Roxana Knobel , Liduína A. R. Sousa , Leila Katz , Eduardo B. Fonseca , Claudia G. Magalhães, Wanderson K. Oliveira , Jorge Rezende-Filho , Adriana S. O. Melo & Melania M. R. Amorim (2020): Maternal mortality and COVID-19, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1786056

Study 200 – 23 cases from UK

Of 23 pregnant women with COVID-19, four were admitted to ITU and one died from basilar artery thrombosis, pulmonary embolism, and diabetic ketoacidosis (click here or Antoun EJOG 1-s2.0-S0301211520304486-main). 20 babies were delivered, incl. one set of twins. All survived. Seven babies were tested for SARS-CoV-2 and all were negative. The hospital is unnamed but from its size and author affiliations is likely to be Birmingham Women’s Hospital which has not previously reported cases. However, they will have been included in the UKOSS report study 92. The clinical details of the maternal death suggest this is the same patient as reported in study 107 as having been delivered at Birmingham Heartlands Hospital. Citation: Antoun L, Taweel NE, Ahmed I, Patni S, Honest H, Maternal COVID-19 infection, clinical characteristics, pregnancy, and neonatal outcome A prospective cohort study, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.07.008

Study 199 – case report of a miscarriage from France

A woman with Covid-19 miscarried at 20 weeks (click here or Hachem EJOG 1-s2.0-S0301211520304668-main). The hospital is unnamed but from author affiliation is René Dubos Hospital, Cergy-Pontoise, a northern suburb of Paris. No authors with this affiliation were included in the GROG series, study 150, so this case has probably not been reported before. Citation: Hachem R, Markou G, Veluppillai C, Poncelet C, Late miscarriage as a presenting manifestation of COVID-19, European Journal of Obstetrics and Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.07.024

Study 198 – 10 cases from USA

Ten pregnant women tested positive for SARS-CoV-2, of whom three were symptomatic (click here or Berkowitz AJOG PIIS0002937820307298). None required medical treatment beyond standard obstetric care. They were cared for at various hospitals managed by the Cleveland Clinic Foundation in Ohio, which appear to be all based around the town of Cleveland itself. If so they have not previously been reported. Citation: Berkowitz KM, Goje O, Eaton J. Implementation of universal testing for SARS-CoV-2 in pregnant women with intended admission for delivery. American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.07.011.

17 July update – studies 192 to 196 added

Study 197 – A case report from Italy

A pregnant woman with Covid-19 at 24 weeks gestation was treated with convalescent plasma (click here or Grisolia AJOG MFM 1-s2.0-S258993332030118X-main). The following day her condition worsened, and she was transferred to ICU where she received non-invasive ventilation. After a 2nd dose of convalescent plasma she recovered. The pregnancy is ongoing.  The hospital is not named but from author affiliations was Carlo Poma Hospital, Mantova. Mantova is in Lombardy so this case was probably included in studies 32 & 64. Citation: Grisolia G, Franchini M, Glingani C, Inglese F, Garuti M, Beccaria M, Capuzzo M, Pinto A, Pavan G, Righetto L, Perotti C, Zampriolo P, De Donno G, Convalescent plasma for COVID-19 in pregnancy: a case report and review, American Journal of Obstetrics & Gynecology MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100174.

Study 196 – 42 cases from Spain

42 women with COVID-19 in the third trimester of pregnancy from 14 hospitals delivered 42 babies (click here or Gabriel apa.15474). One mother died. 3/37 babies tested positive. No babies died. The authors wrote on behalf of the Neo-COVID-19 Research Group. The hospitals were, 12 de Octubre, Clínico San Carlos, Fuenlabrada, Fundación Jiménez Díaz, Getafe, Josep Trueta, La Paz, Hospitales-Madrid Group, Príncipe de Asturias, Puerta de Hierro-Majadahonda, Rey Juan Carlos, Río Hortega, Santiago de Compostela, Sant Joan, Severo Ochoa Leganés, Vall d’Hebrón and the European Institute of Perinatal Mental Health. The cases probably overlap with those in studies 151, 158, 165, 185 &  191. Citation: Marín Gabriel, M.A., Cuadrado, I., Álvarez Fernández, B., González Carrasco, E., Alonso Díaz, C., Llana Martín, I., Sánchez, L., Olivas, C., de las Heras, S., Criado, E. and (2020), Multi‐centre Spanish study found no incidences of viral transmission in infants born to mothers with COVID‐19. Acta Paediatr. Accepted Author Manuscript. doi:10.1111/apa.15474

Study 195 – 14 first trimester cases from Italy

14 women tested positive for SARS-CoV-2 in the first trimester (click here or cosma turin jmv.26267). No outcomes reported. They were cared for at Sant’ Anna Hospital, Turin, so are likely included in the 23 first trimester cases in study 167. Citation: Cosma, S., Borella, F., Carosso, A., Sciarrone, A., Cusato, J., Corcione, S., Mengozzi, G., Preti, M., Katsaros, D., Di Perri, G. and Benedetto, C. (2020), The “scar” of a pandemic: cumulative incidence of COVID‐19 during the first trimester of pregnancy. J Med Virol. Accepted Author Manuscript. doi:10.1002/jmv.26267

Study 194 – Three cases from Vitoria, Espirito Santo State, Brazil.

Two women with severe Covid-19 in pregnancy, and one with severe disease postnatally, required prolonged ICU admission and ventilation (click here or dos Reis Case Rep Brazil). One mother died. All three babies tested negative and survived. This is the first scientific report from this city. However, the woman who died may be included in studies 66, 138 & 182. Citation: Reis Helena Lucia Barroso dos, Boldrini Neide Aparecida Tosato, Caldas João Victor Jacomele, Paz Ana Paula Calazans da, Ferrugini Carolina Loyola Prest, Miranda Angelica Espinosa. Severe coronavirus infection in pregnancy: challenging cases report. Rev. Inst. Med. trop. S. Paulo [Internet]. 2020 [cited 2020 July 17] ; 62: e49. Available from: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0036-46652020000100513&lng=en. Epub July 13, 2020. https://doi.org/10.1590/s1678-9946202062049.

Study 193 – Case report from Belgium

A pregnant woman with twins developed mild Covid-19 at 22 weeks gestation (click here or Pulinx 10096_2020_Article_3964). She was nursed at home, but at 24 weeks went into spontaneous labour. One twin was stillborn and the other died soon after birth. Amniotic fluid and placental tissue tested positive for SARS-CoV-2. From author affiliations this was probably Sint-Trudo Hospital in Sint-Truiden, which has not previous reported cases. Citation: Pulinx, B., Kieffer, D., Michiels, I. et al. Vertical transmission of SARS-CoV-2 infection and preterm birth. Eur J Clin Microbiol Infect Dis (2020). https://doi.org/10.1007/s10096-020-03964-y

Study 192 – Case report from Zhongshan, in Guangdong Province, China.

A mother with Covid-19 at 35 weeks gestation suffered from a cytokine storm, and required both ventilation and ECMO (click here or Wang 1-s2.0-S0002937820307286-main). She survived, but the baby died. As the authors note this case was included in Study 3. The hospital, mother’s age, gestational age and baby outcome all suggest she is also the same woman as in studies 57 and 81. Citation:  Wang X, Wang D, He S, The role of a cytokine storm in severe COVID-19 disease in pregnancy, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.07.010.

16 July update – studies 188 – 191 added

Study 191 – 27 cases from Spain

This preprint reports 27 pregnant women with COVID-19 of whom seven developed some features of HELLP syndrome (click here or 2020.07.10.20133801v1.full). The details are difficult to interpret but I think 12 delivered, 5 by Caesarean, and no mothers or babies died. The patients were cared for in two unnamed hospitals which from author affiliations were probably Hospital de la Santa Creu i Sant Pau and Hospital Sant Joan de Deu, both in Barcelona. These hospitals have not previously reported cases under their own names. However, the patients may have been included in the Spanish Covi-Preg registry study 151. Citation: Francesc Figueras, Elisa LLurba, Raigam Martinez-Portilla, Josefina Mora, Fatima Crispi, Eduard Gratacos. COVID-19 causing HELLP-like syndrome in pregnancy and role of angiogenic factors for differential diagnosis. medRxiv 2020.07.10.20133801; doi: https://doi.org/10.1101/2020.07.10.20133801

Study 190 – Two cases from Italy

Two pregant women with diabetes contracted Covid -19. Clinical details are given for only one who recovered (click here or ijgo.13306). Both were cared for in Papa Giovanni XXIII Hospital in Bergamo between Feb 22 & May 17, 2020 so have probably been reported in studies 32, 64, 114 & 117. Citation: Dodesini, A.R., Galliani, S., Ciriello, E., Bellante, R. and Trevisan, R. (2020), Pre‐gestational diabetes during the COVID‐19 pandemic in Bergamo, Italy. Int J Gynecol Obstet. Accepted Author Manuscript. doi:10.1002/ijgo.13306

Study 189 – 185 cases from Kuwait

This preprint reports 185 pregnant women with Covid-19 treated in New-Jahra Hospital, where all pregnant women with Covid-19 in Kuwait are treated, between March 15th & May 31st 2020 (click here or 2020.07.10.20150623v1.full). No mothers died or required ECMO, although two required ventilation. Three women miscarried, and 41 babies delivered. Two babies tested positive but none died.  Citation: Amal Ayed, Alia Embaireeg, Asmaa Benawadth, Wadha Al-Fouzan, Majeda Hammoud, Monif Alhathal, Abeer Alzaydai, Mariam Ayed. Maternal and perinatal characteristics and outcomes of pregnancies complicated with COVID-19 in Kuwait. medRxiv 2020.07.10.20150623; doi: https://doi.org/10.1101/2020.07.10.20150623 For published verion (click here).

Study 188 – Four, possibly five, cases from Italy

Four pregnant women with Covid-19 and a further woman who had possible pneumonia one day after delivering twins and two months later had SARS-CoV-2 IgG antibodies, are reported (click here or 10.1080@14767058.2020.1791817) All mothers and babies survived although one of the four definite Covid-19 mothers developed Guillain-Barré syndrome and remains in hospital. All patients were cared for Bolognini Hospital which is a “spoke center” for COVID 19 in pregnancy in Seriate, Bergamo in Lombardy. It is thus likely that they were included in studies 32, 64 & 117. Citation: Paola Algeri, Valentina Stagnati, Maria Donata Spazzini, Cristina Bellan, Alessandro Montanelli, Gianluigi Patelli & Massimo Ciammella (2020) Considerations on COVID-19 pregnancy: a cases series during outbreak in Bergamo Province, North Italy, The Journal of Maternal-Fetal & Neonatal Medicine, DOI: 10.1080/14767058.2020.1791817

15 July update – study 187 added

Study 187 – Case report of neonatal infection from France

A woman contracted Covid-19 at 35 weeks, required Caesarean for fetal distress, and recovered with supportive treatment (click here or s41467-020-17436-6). The baby was initially well but developed neurological symptoms on day 3. Maternal nasopharynx (NP), blood, placental, vaginal and amniotic samples were all positive for SARS-CoV-2. Baby blood and rectal samples, as well as NP samples on days 1, 3 and 18, were also positive. The baby recovered with supportive treatment. From author affiliations the hospital was Antoine Béclère, Paris. Although not cited, this is case two in study 48. The papers share two authors, Alexandra J Vivanti & Alexandra Benachi, from the same hospital, and all reported maternal and baby characteristics, as well as all the mother’s blood values on the day of birth, are identical. Citation: Vivanti, A.J., Vauloup-Fellous, C., Prevot, S. et al. Transplacental transmission of SARS-CoV-2 infection. Nat Commun 11, 3572 (2020). https://doi.org/10.1038/s41467-020-17436-6

13 July update – study 186 added

Study 186 – Case report from USA

A woman with Covid-19 gave birth vaginally at 34 weeks (click here or INTRAUTERINE_TRANSMISSION_OF_SARS_COV_2_INFECTION.96099). Despite isolation from the mother, the baby was infected SARS-CoV-2. Mother and baby were cared for at Parkland Health & Hospital System, Dallas, Texas which has not previously reported cases. Citation: Sisman, Julide; Jaleel, Mambarambath A; Moreno, Wilmer; Rajaram, Veena; Collins, Rebecca R.J; Savani, Rashmin; Rakheja, Dinesh; Evans, Amanda S. INTRAUTERINE TRANSMISSION OF SARS-COV-2 INFECTION IN A PRETERM INFANT, The Pediatric Infectious Disease Journal: July 10, 2020 – Volume Online First – Issue – doi: 10.1097/INF.0000000000002815

12 July update – studies 183 to 185 added

Study 185 – Two cases from Spain

The fetuses of two pregnant women with Covid-19 developed transient skin oedema at 21 and 25 weeks gestation (click here or Fetal_Transient_Skin_Edema_in_Two_Pregnant_Women.97307). One mother, cared for at Vall d’Hebron University Hospital in Barcelona, had severe disease requiring ventilation. The other, hospital not stated, had mild disease only. Amniotic fluid was negative for SARS-CoV-2 in both cases. Both resolved and the pregnancies are ongoing. The Barcelona case at least was probably included in study 140. Citation: Garcia-Manau P, Garcia-Ruiz I, Rodo C, et al. Fetal Transient Skin Edema in Two Pregnant Women With Coronavirus Disease 2019 (COVID-19) [published online ahead of print, 2020 Jul 7]. Obstet Gynecol. 2020;10.1097/AOG.0000000000004059. doi:10.1097/AOG.0000000000004059

Study 184 – 100 cases from France

One hundred pregnant women with Covid-19 were treated in four Paris hospitals between March 12 & April 13, 2020 (click here). Ten were admitted to ICU of whom 9 required intubation. There were no stillbirths or miscarriages, but one neonatal death due to prematurity. All neonates were tested for SARS-CoV-2. One was positive but did not show signs of respiratory illness. The hospitals were Antoine Béclère, Clamart; Bicêtre Hospital, Le Kremlin Bicêtre; Louis-Mourier, Colombes; and Centre Hospitalier Sud Francilien, Evry. They therefore include one of the cases in study 48, are included in study 150 and probably also overlap with those in study 157. Citation: Vivanti AJ, Mattern J, Vauloup-Fellous C, Jani J, Rigonnot L, El Hachem L, Le Gouez A, Desconclois C, Ben M’Barek I, Sibiude J, Benachi A, Picone O, Cordier AG. Retrospective Description of Pregnant Women Infected with Severe Acute Respiratory Syndrome Coronavirus 2, France. Emerg Infect Dis. 2020 Jul 6;26(9). doi: 10.3201/eid2609.202144. Online ahead of print.

Study 183 – 18 cases from China

Between Jan 30, & Mar 1, 2020, 10 clinically diagnosed and 8 swab positive pregnant women with COVID-19 were treated at Renmin Hospital of Wuhan University (click here or s12884-020-03026-3). These cases probably overlap with studies 10, 36, 37, 40, and 80. They are also likely to be included in studies 55 & 57. Citation: Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) infection during late pregnancy: a report of 18 patients from Wuhan, China. Zhang L, Dong L, Ming L, Wei M, Li J, Hu R, Yang J. BMC Pregnancy Childbirth. 2020 Jul 8;20(1):394. doi: 10.1186/s12884-020-03026-3.

11 July update study 181 & 182  added. Latter HT Fred Peret.

Study 182 – 124 maternal deaths from Covid-19 in Brazil

Between Feb 26 & June 18, 978 pregnant and postpartum women with COVID-19 were registered with the Brazilian Ministry of Health’s Acute Respiratory Distress Syndrome (ARDS) Surveillance System, of whom 124 died (click here or IJOGfinal (1)). They probably include five cases from study 66Citation: Takemoto, M.L.S., Menezes, M.O., Andreucci, C.B., Nakamura‐Pereira, M., Amorim, M.M.R., Katz, L. and Knobel, R. (2020), The tragedy of COVID‐19 in Brazil: 124 maternal deaths and counting. Int J Gynecol Obstet. Accepted Author Manuscript. doi:10.1002/ijgo.13300

Study 181 – Rise in stillbirths during pandemic in UK capital

Nineteen women with Covid-19 were cared for at St Georges Hospital in London during the period February 1 to June 14, 2020. None experienced stillbirth. However the overall stillbirth rate in the hospital was significantly higher than in the pre-pandemic period (click here or jama_khalil_2020_ld_200076). Included in study 92. Citation: Khalil A, von Dadelszen P, Draycott T, Ugwumadu A, O’Brien P, Magee L. Change in the Incidence of Stillbirth and Preterm Delivery During the COVID-19 Pandemic. JAMA. Published online July 10, 2020. doi:10.1001/jama.2020.12746

4th July update – studies 178 -180 added.

Study 180 – case report of postnatal Covid-19 from Italy

A mother developed pyrexia on day two after a normal birth, and both her and her baby tested positive (click here or e20201121.full). The baby was cared for in Fondazione Monza e Brianza per il Bambino e la sua Mamma and Azienda Socio Sanitaria Territoriale-Monza. Monza is in Lombardy so this case may be included in studies 32, 64, 109 & 114. However as a postnatal case it may not. We’re keeping an open mind.  Citation: Sinelli M, Paterlini G, Citterio M, et al. Early Neonatal SARS-CoV-2 Infection Manifesting With Hypoxemia Requiring Respiratory Support. Pediatrics. 2020;146(1):e20201121

Study 179 – 67 cases from USA

67 women with SARS-CoV-2 infection from March 13 to April 24, (click here or s-0040-1713851). Patients cared for in seven hospitals within the Northwell Health system in New York: North Shore University Hospital, Long Island Jewish Medical Center, Long Island Jewish Forest Hills, Huntington Hospital, Southside Hospital, Lenox Hill Hospital, and Staten Island University Hospital. The patients probably overlap with those reported in studies 49, 83, 113,118,134 & 162. Citation: Moti Gulersen, Matthew J. Blitz, Burton Rochelson, Michael Nimaroff, Weiwei Shan, Eran Bornstein Clinical Implications of SARS-CoV-2 Infection in the Viable Preterm Period. Am J Perinatol DOI: 10.1055/s-0040-1713851

Study 178 – Ten cases from China

Ten pregnant women with COVID-19, treated in the Zhongnan Hospital of Wuhan University (grid.413247.7) from Jan 20 to Feb 6 (click here or 10.1371@journal.pone.0235134). These women are probably also included in studies 1, 13, 55 & 57, and may also overlap with study 75. Citation: Gong X, Song L, Li H, Li L, Jin W, Yu K, et al. (2020) CT characteristics and diagnostic value of COVID-19 in pregnancy. PLoS ONE 15(7): e0235134. https://doi.org/10.1371/journal.pone.0235134

3rd July update – study 177 added. Study 176 removed. Duplicate of study 89.  Jim’s mistake. HT Keelin.

Study 177 – CTG changes in 12 Covid-19 pregnancies, Spain

Intrapartum electronic fetal cardiotocograms (CTGs) from 11 women with Covid-19 and one antepartum CTG at 28 weeks, were evaluated using a physiological system (click here or PIIS0301211520304243). All eleven delivered babies had normal Apgar scores and cord pH. No details of maternal severity, mode of delivery or other baby details were given. Some patients had been cared for in Puerta de Hierro hospital, Madrid, which also included cases in studies 125 and 151.  Others came from Germans Trias i Pujol Hospital, Badalona, a northern suberb of Barcelona, which has not previously reported cases. Citation: Gracia-Perez-Bonfils A, Martinez-Perez O, Llurba E, Chandraharan E, Fetal heart rate changes on the cardiotocograph trace secondary to maternal COVID-19 infection, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.06.049

1 July update – study 176 added.

Study 176 – Case report from San Francisco. Deleted 3 July duplicate of study 89

A 34 year old woman contracted Covid-19 at 28 weeks gestation (click here or Acute_Respiratory_Distress_Syndrome_in_a_Preterm.11). She required ventilation and was delivered by Caesarean section. The baby tested negative. Both recovered. The hospital is not named but authors are all affiliated with University of California, San Francisco. Citation: Blauvelt, Christine A. MD; Chiu, Catherine MD; Donovan, Anne L. MD; Prahl, Mary MD; Shimotake, Thomas K. MD; George, Ronald B. MD, FRCPC; Schwartz, Brian S. MD; Farooqi, Naghma A. MD; Ali, Syed S. MD; Cassidy, Arianna MD; Gonzalez, Juan M. MD, PhD; Gaw, Stephanie L. MD, PhD Acute Respiratory Distress Syndrome in a Preterm Pregnant Patient With Coronavirus Disease 2019 (COVID-19), Obstetrics & Gynecology: July 2020 – Volume 136 – Issue 1 – p 46-51 doi: 10.1097/AOG.0000000000003949

30 June update – study 175 added

Study 175 – 5 cases from Philadelphia, Pennsylvania, USA

Five pregnant women with Covid-19 were treated with remdesivir (click here or mccoy remdesevir ajogmfm). Three were ventilated, four delivered and all recovered. One pregnancy is ongoing.  All neonates tested negative. From author affiliations these cases may overlap with studies 65 and 86. Citation: Mccoy JA, Short WR, Srinivas SK, Levine LD, Hirshberg A, Compassionate use remdesivir for treatment of severe COVID-19 in pregnant women at a United States academic center, American Journal of Obstetrics & Gynecology MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100164.

26 June update –  study 174 added

Study 174 – US CDC Covid-19 & pregnancy weekly tracking data

The US Centers for Disease Control (CDC) are now publishing weekly COVID-19 in pregnancy tracking data. The June 25th update (click here) duplicates that in study 172. Citation: US CDC Weekly COVID-19 Pregnancy Data; Pregnant women with COVID-19, United States [January 22-June 23, 2020] https://www.cdc.gov/coronavirus/2019-ncov/cases-updates/special-populations/pregnancy-data-on-covid-19.html Accessed 26 June 2020.

25 June update – studies 171 to 173 added. (Study 173 belatedly). Study 43 withdrawn

Study 173 – 33 cases from Covid-Net

An April 6th MMWR, which we had previously missed, of SARS-CoV-2 hospitalisations reported to COVID-NET, a network of hospitals representing about 10% of the United States, included 33 pregnant women of whom 3 (9%) had been hospitalised (click here or mm6915e3-H). These cases overlap with studies 171 and 172. Citation: Garg S, Kim L, Whitaker M, et al. Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 — COVID-NET, 14 States, March 1–30, 2020. MMWR Morb Mortal Wkly Rep 2020;69:458–464. DOI: http://dx.doi.org/10.15585/mmwr.mm6915e3external icon

Study 172 – 8,207 pregnant woman with SARS-CoV-2 from CDC

Of 8,207 pregnant women who tested positive for SARS-CoV-2 and were reported to the US Centers For Disease Control by 7th June, 2,587 (31.5%) were hospitalised, 120 (1.5%) admitted to ICU, 42 (0.5%) ventilated, and 16 (0.2%) died. Comparative figures for 83,205 non-pregnant women in the same age group were; 4,840 (5.8) hospitalised, 757 (0.9%) admitted to ICU, 225 (0.3%) ventilated, 208 (0.2%) died (click here or mm6925a1-H). Citation: Ellington S, Strid P, Tong VT, et al. Characteristics of Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status — United States, January 22–June 7, 2020. MMWR Morb Mortal Wkly Rep 2020;69:769–775. DOI: http://dx.doi.org/10.15585/mmwr.mm6925a1external icon

Study 171 – 36 cases from Covid-Net 

In this MedRxiv preprint, of 2,491 adults hospitalised with Covid-19, in the US Covid-Net database (154 acute hospitals in 13 states), 26 were pregnant. This represent 12.9% of the 279 women of childbearing age (15–49 years) in the cohort (click here or 2020.05.18.20103390v1.full). [Comment – see table 1. The percentage seems to be wrong.] Citation: Lindsay Kim, Shikha Garg, Alissa O’Halloran, Michael Whitaker, Huong Pham, Evan J. Anderson, Isaac Armistead, Nancy M. Bennett, Laurie Billing, Kathryn Como-Sabetti, Mary Hill, Sue Kim, Maya L. Monroe, Alison Muse, Arthur Reingold, William Schaffner, Melissa Sutton, H. Keipp Talbot, Salina M. Torres, Kimberly Yousey-Hindes, Rachel A Holstein, Charisse Cummings, Lynette Brammer, Aron Hall, Alicia Fry, Gayle E. Langley. Interim Analysis of Risk Factors for Severe Outcomes among a Cohort of Hospitalized Adults Identified through the U.S. Coronavirus Disease 2019 (COVID-19)-Associated Hospitalization Surveillance Network (COVID-NET) medRxiv 2020.05.18.20103390; doi: https://doi.org/10.1101/2020.05.18.20103390

24 June update – studies 165 to 170 added

Study 170 – 241 cases from the Netherlands

The 19th June update of NethOSS (click here), accessed 24 June 2020, contains the following. 6/224 women with brief additional details were admitted to intensive care. One mother died. 69 women have given birth, 26 by Caesarean. 152 pregnancies are ongoing. No baby has died. No babies were infected. Citation: See Studies 42, 46, 120, 141, & 147. Available here. Accessed 24 June 2020.

Study 169 – 19 June ICNARC report

The 19th June ICNARC update (click here or ICNARC COVID-19 report 2020-06-19.pdf) contains 26 currently, and 37 recently, pregnant women critically ill with Covid-19.  Of these 10 are currently, and 24 have in the past,  received advanced respiratory support. NOTE – ICNARC has recently started reporting pregnancy data subdivided by white/non white ethnicity.

Study 168 – The PRIORITY study 24 June 2020

The PRIORITY (Pregnancy Coronavirus Outcomes Registry) study (click here) has issued no formal reports yet. However the dashboard (click here accessed 24 June 2020) shows 882 participants, by age group, gestational age band, ethnic group and US state of residence. Citation: University of California San Francisco. PRIORITY Study dashboard https://priority.ucsf.edu/dashboard. Accessed 24 June 2020.

Study 167 – 23 women in the first trimester from Italy

Of 23 women in this preprint from Medxiv, testing positive for SARS-Cov2 in the first trimester, 11 miscarried and 12 had ongoing pregnancies (click here or 2020.06.19.20135749v1.full). 12 October update. Published in AJOG here or PIIS0002937820311777). This was a case control study comparing SARS-Cov2 rates between women experiencing miscarriage and matched women with ongoing pregnancy. The rates did not differ significantly. The patients were cared for at S. Anna Hospital, Turin, which has not previously reported cases in the first trimester. Citation: Stefano Cosma, Andrea Carosso, Jessica Cusato, Fulvio Borella, Marco Carosso, Marialuisa Bovetti, Claudia Filippini, Antonio D’Avolio, Valeria Ghisetti, Giovanni Di Perri, Chiara Benedetto. COVID-19 and first trimester spontaneous abortion: a case-control study of 225 pregnant patients. medRxiv 2020.06.19.20135749; doi: https://doi.org/10.1101/2020.06.19.20135749&nbsp;

12 October update. Published in AJOG (here or PIIS0002937820311777). AJOG citation: Stefano COSMA, Andrea R. CAROSSO, Jessica CUSATO, Fulvio BORELLA, Marco CAROSSO, Marialuisa BOVETTI, Claudia FILIPPINI, Antonio D’AVOLIO, Valeria GHISETTI, Giovanni DI PERRI, Chiara BENEDETTO, COVID-19 and first trimester spontaneous abortion: a case-control study of 225 pregnant patients, American Journal of Obstetrics and Gynecology, 2020, ISSN 0002-9378, https://doi.org/10.1016/j.ajog.2020.10.005.

Study 166 – 3 cases from China

Three pregnant woman with Covid-19 were all delivered by Caesarean (click here or E603.full).  The babies all tested negative. The mothers came from a cohort of 166 pregnant women testing positive for SARS-Cov19 in a predefined administrative region containing 12 hospitals, including the Xiangyang First People’s Hospital in Hubei, China. This hospital is not found on GRID.ac. Citation: Peng An, Bradford J. Wood, Wei Li, Min Zhang, Yingjian Ye. Postpartum exacerbation of antenatal COVID-19 pneumonia in 3 women. CMAJ Jun 2020, 192 (22) E603-E606; DOI: 10.1503/cmaj.200553

Study 165 – 65 cases from Madrid

Of 65 women with Covid-19, 13 were diagnosed postnatally. Of the 52 antenatal cases, 32 developed pneumonia and two required ICU admission (click here or PIIS2589537020301516. No mother died.  6/32 women with pneumonia had delivered and no babies were infected. Patients were cared for at University Hospital “12 de Octubre”. They therefore probably overlap with those reported in study 151 but differ from those in study 125. Citation: R. San-Juan et al., Incidence and clinical profiles of COVID-19 pneumonia in pregnant women: A single-centre cohort study from Spain, EClinicalMedicine (2020), https://doi.org/10.1016/j.eclinm.2020.100407

23 June update – studies 163 & 164 added

Study 164 – Two cases from USA

One woman with severe Covid-19 miscarried at 22 weeks. At the time of writing she remained ventilated. Another woman required Caesarean birth at 29 weeks and recovered. Her baby required intubation and tested positive for SARS-Cov2 at 6 days (click here or Futterman NY s-0040-1712978).  The hospital is not named. Author affiliations are Dept. OBGYN, New York Medical College, Valhalla, which is affiliated with multiple clinical sites. These cases may therefor have been previously reported. Citation: Itamar Futterman, Miriam Toaff, Liel Navi, Camille A. Clare. COVID-19 and HELLP: Overlapping Clinical Pictures in Two Gravid Patients. Am J Perinatol Rep 2020;10:e179–e182.

Study 163 – 9 cases with placental histology from Italy

Of 9 women with SARS-CoV2 infection delivered between March and April 2020 at Fondazione IRCCS Ca’ Granda – Ospedale Maggiore Policlinico (Milan), all mothers recovered and all babies tested negative (click here or Cribiu Eur JOG IIS0301211520304164). Placental histology is reported. Although the hospital name differs these cases are probably included in studies 32 & 64. Citation: Cribi `u FM, Croci GA, Gobbo AD, Rizzuti T, Iurlaro E, Tondo M, Viscardi A, Bosari S, Ferrero S, HISTOLOGICAL CHARACTERIZATION OF PLACENTA IN COVID19 PREGNANT WOMEN, European Journal of Obstetrics and amp; Gynecology and Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.06.041

21 June update – studies 161 & 162 added

Study 162 – 462 cases (70 severe) from New York, USA

Of 462 pregnant women with Covid-19, 70 had severe disease, 14 were admitted to ICU, and two died (click here or PIIS0002937820306360). The patients were cared for in the Northwell Hospital network which includes Maimonides Medical Centre. The paper includes a statement about severe case overlap with studies 113, 118 & 134. Shared authorship suggests overlap with studies 49 and 83 as well. Citation: Blitz MJ, Rochelson B, Minkoff H, Meirowitz N, Prasannan L, London V, Rafael TJ, Chakravarthy S, Bracero LA, Wasden SW, Pachtman Shetty SL, Santandreu O, Chervenak FA, Schwartz BM, Nimaroff M, Maternal Mortality Among Women with COVID-19 Admitted to the Intensive Care Unit, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.06.020.

Study 161 – 54 cases from France

Of 54 pregnant women with confirmed (n=38) or suspected (n=16) COVID-19 in pregnancy treated at Strasbourg University Hospital from March 1 to April 3, there was one miscarriage, 21 live births (12 vaginal, 9 cesarean), and 32 ongoing pregnancies (click here or PIIS0002937820306396). Five women were admitted to ICU, three required mechanical ventilation and one ECMO. No mothers died, although at the time of writing the woman on ECMO remained on it. All babies tested negative & none died. Strasbourg doctors co-authored the GROG report, so these cases are probably included in study 150. Citation: Sentilhes L, De Marcillac F, Jouffrieau C, Kuhn P, Thuet V, Hansmann Y, Ruch Y, Fafi-Kremer S, Deruelle P, COVID-19 in pregnancy was associated with maternal morbidity and preterm birth, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.06.022.

18 June update – studies 157-160 added

Study 160 – 241 cases from USA

Of 241 pregnant women with laboratory-confirmed SARSCoV-2 infection who gave birth between March 13 & April 12, there were 245 live births to 241 women (6 sets of twins), & 2 stillbirths (click here or Characteristics_and_Outcomes_of_241_Births_to.97310). 17 women were admitted to ITU and 9 intubated. No mothers died, although one woman remained intubated at time of writing. 27% of neonates were admitted to NICU. Of liveborns with SARS-CoV-2 test results 236/230 tested negative. No further neonatal outcomes reported. The five hospitals were “Montefiore Medical Center; Mount Sinai Health System, including Mount Sinai Hospital and Mount Sinai West; its affiliate, NYC Health and Hospitals- Elmhurst Hospital; NY-Presbyterian Hospital- Columbia University; and NY University Langone Health, including NYU Langone Hospitals, Manhattan campus, and NYU Langone Hospitals-Brooklyn”. These cases therefore likely overlap with studies 14, 27, 41, 49, 83, 85, 86, 95, 95, 119, 135, 136, & 152. They probably do not overlap with women in studies 61, 113, 118, 122 & 134, which included women cared for in different centres. Women in Study 99 are unclear. Citation: Khoury, Rasha MD, MPH; Bernstein, Peter S. MD; Debolt, Chelsea MD; Stone, Joanne MD; Sutton, Desmond M. MD; Simpson, Lynn L. MD; Limaye, Meghana A. MD; Roman, Ashley S. MD; Fazzari, Melissa PhD; Penfield, Christina A. MD; Ferrara, Lauren MD; Lambert, Calvin MD; Nathan, Lisa MD; Wright, Rodney MD; Bianco, Angela MD; Wagner, Brian MD; Goffman, Dena MD; Gyamfi-Bannerman, Cynthia MD; Schweizer, William E. MD; Avila, Karina MPH; Khaksari, Bijan MPH; Proehl, Meghan MPH; Heitor, Fabiano MD; Monro, Johanna BS; Keefe, David L. MD; D’Alton, Mary E. MD; Brodman, Michael MD; Makhija, Sharmila K. MD; Dolan, Siobhan M. MD Characteristics and Outcomes of 241 Births to Women With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection at Five New York City Medical Centers, Obstetrics & Gynecology: June 16, 2020 – Volume Publish Ahead of Print – Issue – doi: 10.1097/AOG.0000000000004025

Study 159 – Three severe cases from USA

Three pregnant women with Covid-19 required ventilation (click here or s-0040-1713664). All three recovered and their pregnancies are ongoing. They were cared for in Morristown Medical Center and St. Peter’s University Medical Center in central New Jersey, neither of which have previously reported cases. Citation: Lucarelli E, Behn C, Lashley S, Smok D, Benito C, Oyelese Y. Mechanical Ventilation in Pregnancy Due to COVID-19: A Cohort of Three Cases [published online ahead of print, 2020 Jun 16]. Am J Perinatol. 2020;10.1055/s-0040-1713664. doi:10.1055/s-0040-1713664

Study 158 – Four patients undergoing amniocentesis from Spain.

Four pregnant women with Covid-19 underwent midtrimester amniocentesis for prenatal diagnosis of other conditions (click here or 1-s2.0-S0014256520301569-main). No amniotic samples tested positive. The hospital is not named but from author affiliations is probably Hospital Universitario Maternal-Infantil de Jaén, Jaén. This hospital has not previously reported cases, but these cases may be included in study 151 which included registry cases. Citation: Hijona Elósegui JJ, et al. ¿Existe transmisión materno-fetal del SARS-CoV-2 durante la gestación? Rev Clin Esp. 2020. https://doi.org/10.1016/j.rce.2020.06.001

Study 157 – 88 cases from France

Eighty eight pregnant women with Covid-19 responded to an anonymous internet survey hosted by the French television pregnancy show “la Maison des Maternelles” (click here or PIIS030121152030364X). 6 had been sufficiently severe to require oxygen. 14 had delivered, 5 by Caesarean. Many are probably included in study 150. Citation: J. Cohen, et al., Covid-19 in pregnant women: General data from a French National Survey, Eur J Obstet Gynecol (2020), https://doi.org/10.1016/j.ejogrb.2020.06.002

16 June update study 156 added

Study 156 – Case report of Covid-19, pregnancy & pancreatitis, USA

A 36-year-old woman contracted Covid-19 at 33 weeks (click here or 1-s2.0-S2214911220300588-main). Pancreatitis was diagnosed on the basis of raised lipase, despite normal amylase. She recovered and was later delivered by Caesarean. Both mother & baby discharged  in stable condition. Author affiliations Saint Joseph Hospital, Denver, Colorado. Citation: Sarah R. Rabice, Paulina C. Altshuler, Claire Bovet, Cathlyn Sullivan, Amy J. Gagnon. COVID-19 infection presenting as pancreatitis in a pregnant woman: A case report. Case Reports in Women’s Health. Volume 27, 2020, e00228, ISSN 2214-9112, https://doi.org/10.1016/j.crwh.2020.e00228.

15 June update study 155 added

Study 155 – Case report of placental infection from USA

This MedRxiv preprint (click here or SARS-CoV-2 infection of the placenta (002)) (click here for published peer reviewed version update 24 June) reports a 35-year-old woman who contracted Covid-19 at 22 weeks gestation. She had coagulopathy and hypertension, and was offered and accepted pregnancy termination, which was performed under GA with extubation on day 1.  SARS-CoV-2 RNA was present at high levels in the placenta, and virions were visible on electron microscopy. The hospital is not named but author affiliations are Yale School of Medicine. The case is therefore probably included in study 132Citation: Hillary Hosier, Shelli Farhadian, Raffaella Morotti, Uma Deshmukh, Alice Lu-Culligan, Katherine Campbell, Yuki Yasumoto, Chantal Vogels, Arnau Casanovas-Massana, Pavithra Vijayakumar, Bertie Geng, Camila Odio, John Fournier, Anderson Brito, Joseph Fauver, Feimei Liu, Tara Alpert, Reshef Tal, Klara Szigeti-Buck, Sudhir Perincheri, Christopher Larsen, Aileen Gariepy, Gabriela Aguilar, Kristen Fardelmann, Malini Harigopal, Hugh Taylor, Christian Pettker, Anne Wyllie, Charles Dela Cruz, Aaron Ring, Nathan Grubaugh, Albert Ko, Tamas Horvath, Akiko Iwasaki, Uma Reddy, Heather Lipkind.  SARS-CoV-2 Infection of the Placenta. medRxiv 2020.04.30.20083907; doi: https://doi.org/10.1101/2020.04.30.20083907

Update 24 June. Peer reviewed citation, [online ahead of print, 2020 Jun 23]. J Clin Invest. 2020;139569. doi:10.1172/JCI139569

11 June update studies 154 & 154 added

Study 154 – Case report from Northwick Park Hospital, London, UK

A 34-year woman with immunologic thrombocytopaenia developed a cough, fever, petechiae and gum bleeding at 20 weeks gestation (click here or Nesr BJH case bjh.16928). She had a low platelet count, swabbed positive for SARS-CoV-2 and recovered. Pregnancy outcome not reported, but by implication ongoing. Case presumably included in study 92.  Citation: Nesr, G., Garnett, C., Bailey, C. and Arami, S. (2020), ITP flare with mild COVID‐19 infection in pregnancy: A case report. Br J Haematol. Accepted Author Manuscript. doi:10.1111/bjh.16928

Study 153 – Case report from Jordan

A 30-year-old woman, contracted mild Covid-19 at 36 weeks gestation (click here or Al Zaghal Case Rep Jordan 1-s2.0-S2214911220300424-main). She delivered by Caesarean. The baby tested negative. Both recovered. The first report from this country. Citation: Laila A. AlZaghal, Najwa AlZaghal, Safwan O. Alomari, Nail Obeidat, Basil Obeidat, Wail A. Hayajneh. Multidisciplinary team management and cesarean delivery for a Jordanian woman infected with SARS-COV-2: A case report. Case Reports in Women’s Health 27 (2020) https://doi.org/10.1016/j.crwh.2020.e00212

9 June update – studies 151 & 152 added.

Study 152 – 2 severe cases from New York, USA

Two women with Covid-19 required ventilation and caesarean delivery (click here or Silverstein AmJPerinatol Rep s-0040-1712925). Both neonates tested negative. Both mothers recovered. The hospital(s) are not named but author affiliations suggest either Langone Medical Center or Bellevue Hospital Center. The cases are therefore probably included in studies 85 & 86, and possibly also in studies 49 & 83. Citation: Jenna S. Silverstein, Meghana A. Limaye, Sara G. Brubaker, Ashley S. Roman, Judita Bautista, Judith Chervenak, Adam J. Ratner, Philip M. Sommer, Nicole M. Roselli, Charlisa D. Gibson, David Ellenberg, Christina A. Penfield. Acute Respiratory Decompensation Requiring Intubation in Pregnant Women with SARS-CoV-2 (COVID-19) Am J Perinatol Rep 2020;10:e169–e175.

Study 151 – 82 cases from Spain

Of 82 women with singleton pregnancies and Covid-19, who delivered within 14 days of disease onset, collected from from 96 maternity hospitals, 9 were admitted to ICU and 7 ventilated (click here or jama_martnezperez_2020_ld_200062). Five babies tested positive. No mothers or babies died. The hospitals are not named but author affiliations include Puerta de Hierro University Hospital, 12 Octubre University Hospital, & Gregorio Marañon University Hospital, all three from Madrid. Three other authors are associated with the Covi-Preg registry in Switzerland (click here). The cases probably overlap with those in studies 53125. Citation: Martínez-Perez O, Vouga M, Cruz Melguizo S, et al. Association Between Mode of Delivery Among Pregnant Women With COVID-19 and Maternal and Neonatal Outcomes in Spain. JAMA. Published online June 08, 2020. doi:10.1001/jama.2020.10125

8 June update – study 150 added.

Study 150 – 617 cases from France

Thirty three maternity units from the “Groupe de Recherche en Obstétrique et Gynécologie (GROG)” treated 617 pregnant women with COVID-19 between March 1 & April 14 (click here or GIlles France JOG HR). Eighty three women required nasal oxygen, a further 10 non-invasive ventilation, a further 29 mechanical ventilation and a further six, ECMO.  One woman died. There were 5 miscarriages and 7 stillbirths among the 181 pregnancies which had ended. Among the 190 live births (7 twins & 1 set of triplets) there was one neonatal death. Two babies tested positive. The 33 maternity units (including 24 tertiary referral centers) are not named, although 19 can be guessed from the author affiliations. Citation: Kayem G, Alessandrini V, Azria E, Blanc J, Bohec C, Bornes M, Bretelle F, Ceccaldi P-Franc¸ois, Chalet Y, Chauleur C, Cordier A-Gael, Deruelle P, Desbri`ere R, Doret M, Dreyfus M, Driessen M, Fermaut M, Gallot D, Garab´edian C, Huissoud C, Lecarpentier E, Luton D, Morel O, Perrotin F, Picone O, Rozenberg P, Schmitz T, Sentilhes L, Sroussi J, Vayssi`ere C, Verspyck E, Vivanti AJ, Winer N, A snapshot of the Covid-19 pandemic among pregnant women in France, Journal of Gynecology Obstetrics and Human Reproduction (2020), doi: https://doi.org/10.1016/j.jogoh.2020.101826 [important]

6 June update – study 149 added

Study 149 – 73 cases, 8 severe, from USA

Of 73 pregnant women with COVID-19, 31 were admitted, of whom 8 visited ICU. Of these 6 needed intubation, and 1 ECMO (click here or 1-s2.0-S2589933320300951-main). 7 of the 8 ICU cases were delivered by Caesarean and one remains undelivered.  All babies were isolated and fed artificial or donor milk. All tested negative. All mothers were discharged from intensive care. No babies died but four remain in hospital. No details given of the non ICU cases. The “network’s two largest hospitals” in which the patients were treated are not named. The authors are affiliated with three large hospitals in New Jersey  Hackensack University Medical Center, University Hospital (Newark, New Jersey) and Hackensack Meridian Jersey Shore University Medical Center. The patients are therefore probably different from those reported in Studies 86, and 111. Citation: Romagano MP, Guerrero K, Spillane N, Kayaalp E, Smilen SW, Alvarez M, Alvarez-Perez J, Francis Kim A, Aschner J, Al-Khan A, Perinatal outcomes in critically ill pregnant women with COVID-19, American Journal of Obstetrics & Gynecology MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100151.

5 June update – studies 143 to 148 added.

Study 148 – 29th May ICNARC report

The 29th May ICNARC update (click here or ICNARC COVID-19 report 2020-05-29.pdf) contains 23 currently, and 34 recently, pregnant women critically ill with Covid-19. Of these 10 and 20 respectively had received advanced respiratory support.

Study 147 – 223 cases from the Netherlands

The 5th June  update of NethOSS (click here), accessed 4 June 2020, contains the following. 6/210 women with brief additional details were admitted to intensive care. One mother died. 66 women have given birth, 25 by Caesarean. 142 pregnancies are ongoing. No baby has died. No babies were infected. Citation: See Studies 42, 46, 120, & 141. Available here. Accessed 5 June 2020.

Study 146 – 8 cases from Turkey

Two pregnant women with Covid-19 were delivered by Caesarean at term, one miscarried at 7 weeks and five pregnancies are ongoing (click here or jum.15367).  One delivered baby tested negative. No details are reported of the other. All mothers recovered. The tertiary hospital is not named, but from author affiliations is probably Sehit Prof Dr Ilhan Varank Sancaktepe Training & Research Hospital, Istanbul. These case are therefore unlikely to overlap with those in Studies 31 and 145. Citation: Yassa M, Birol P, Mutlu AM, Tekin AB, Sandal K, Tug N. Lung Ultrasound Can Influence the Clinical Treatment of Pregnant Women With COVID-19 [published online ahead of print, 2020 Jun 1]. J Ultrasound Med. 2020;10.1002/jum.15367. doi:10.1002/jum.15367

Study 145 – Case report from Turkey

A 25 year old woman with Covid-19 was delivered by Caesarean at 38 weeks (click here or 1-s2.0-S0952818020308953-main). The mother recovered and the baby tested negative. The hospital is not named but from author affiliations is likely Necmettin Erbakan University, Meram Faculty of Medicine, Konya. The patient is different from the one in study 31Citation: Resul Yilmaz, FatmaKiliç, Şule Arican, Gülçin Hacibeyoğlu, Halime Süslü, Mustafa Koyuncu, Sema Tuncer Uzun. Anesthetic management for cesarean birth in pregnancy with the novel coronavirus (COVID-19). Journal of Clinical Anesthesia. Available online 27 May 2020. https://doi.org/10.1016/j.jclinane.2020.109921

Study 144 – 2 (or 3) cases from Japan

Of 52 asymptomatic pregnant women screened for SARS-CoV-2 between April 6 and April 27, two tested positive and one, whose partner had Covid-19, was treated as if she was infected despite a negative test (click here or ijgo.13252). All three were delivered by Caesarean section, and their babies isolated. No babies were infected. Patients were cared for in Keio University Hospital, Tokyo. These are the first cases of Sars-Cov2 from this country. Citation: Ochiai, D., Kasuga, Y., Iida, M., Ikenoue, S. and Tanaka, M. (2020), Universal screening for SARS‐CoV‐2 in asymptomatic obstetric patients in Tokyo, Japan. Int J Gynecol Obstet. Accepted Author Manuscript. doi:10.1002/ijgo.13252

Study 143 – 12 cases from Korea

Twelve women with COVID-19 were admitted for delivery between February 26th & to April 3rd 2020 (click here or kja-20204). Four birthed vaginally and 8 by Caesarean. Two babies were stillborn. All patients were cared for at Daegu Fatimal Hospital, (see Study 22 cited in paper). Although there is no explicit statement about whether the patient in Study 22 was included, the clinical details (age and gestation) differ, so it is likely that all 12  have not previously been reported.  Citation: Jeongmin Oh, Eunju Kim, Hyunkyum Kim, Sang-Ah Lee, Kyeong Hee Lee, Mi Hyae Yu, Jihyun An. Infection control of operating room and anesthesia for cesarean section during pandemic Coronavirus disease-19 (COVID-19) outbreak in Daegu, the republic of Korea – 8 cases report. Korean J Anesthesiol DOI: https://doi.org/10.4097/kja.20204 [Epub ahead of print]. Published online June 5, 2020.

4th June update – studies 141 and 142 added

Study 142 – 61 cases from USA

Of these 61 women with Covid-19 in pregnancy, cared for at a single academic medical centre, 21 were admitted to hospital, of whom 6 went to intensive care, of whom four were intubated (click here or Prevalence_and_Severity_of_Coronavirus_Disease.97338). No mothers died. The hospital is not named, but from author affiliations is likely Massachusetts General Hospital, Boston, Mass. If so, these women probably differ from those reported in Study 129, and have not previously been reported. Citation: Goldfarb, Ilona Telefus MD, MPH; Clapp, Mark A. MD, MPH; Soffer, Marti D. MD, MPH; Shook, Lydia L. MD; Rushfirth, Katherine CNM, MSN; Edlow, Andrea G. MD, MSc; Boatin, Adeline A. MD, MPH; Kaimal, Anjali J. MD, MAS; Barth, William H. Jr MD; Bryant, Allison S. MD, MPH Prevalence and Severity of Coronavirus Disease 2019 (COVID-19) Illness in Symptomatic Pregnant and Postpartum Women Stratified by Hispanic Ethnicity, Obstetrics & Gynecology: June 02, 2020 – Volume Publish Ahead of Print – Issue – doi: 10.1097/AOG.0000000000004005

Study 141 – 201 women from the Netherlands Covid in pregnancy registry

The 22nd May update of NethOSS (click here), accessed 4 June 2020, contains the following. 7/176 women with brief additional details were admitted to intensive care. One mother died after prolonged admission and intubation as a result of pulmonary infection with multiple pulmonary emboli. 49 women have given birth, 16 by Caesarean. 124 pregnancies are ongoing. No baby has died. No babies were infected. Citation: See Studies 42, 46 & 120. Available here. Accessed 4 June 2020. Update 9 September – Professor Kitty Bloemenkamp @kBloemenkamp, chair Birth Centre, Wilhelmina’s Children Hospital, University Medical Centre, Utrecht, and senior author of study 826 assures me that to date there have been no maternal deaths from Covid in the Netherlands.

2nd June update – study 140 added

Study 140 – 42 cases from Spain

Forty two pregnant women with Covid-19 between March 13 & April 10 (click here or 1471-0528.16339). Eight required admission to ICU of whom 6 developed some features of pre-eclampsia, 4 requiring Caesarean, one of which was due to HELLP syndrome. No maternal or baby outcomes are reported but it is implied “after recovery from severe pneumonia, hypertensive therapy was no longer required in all cases” that all women recovered. The “tertiary care” hospital is not named but from author affiliations is likely to be Hospital Universitari Vall d’Hebron, Universitat Autònoma de Barcelona. If so, these cases have not been previously reported. Citation: Mendoza, M., Garcia‐Ruiz, I., Maiz, N., Rodo, C., Garcia‐Manau, P., Serrano, B., Lopez‐Martinez, R.M., Balcells, J., Fernandez‐Hidalgo, N., Carreras, E. and Suy, A. (2020). Preeclampsia‐like syndrome induced by severe COVID‐19: a prospective observational study. BJOG. doi:10.1111/1471-0528.16339

1st June update – Studies 138 (HT Frederico Amedee Peret) & 139 added. Study 137 removed.

Study 139 – 13 cases in USA

Twelve women with Covid-19 were detected through targeted testing, and one by universal screening (click here or ciaa675). No separate clinical details given for the SARS-Cov2 positive women.  Patients were treated at the University of Washington Montlake Labor and Delivery Unit and Northwest Birth Center. They therefore likely overlap with Study 102. Citation: Sylvia M LaCourse, Alisa Kachikis, Michela Blain, LaVone E Simmons, James A Mays, Amber D Pattison, Carol C Salerno, Stephen A McCartney, Nicole M Kretzer, Rebecca Resnick, Rosemary L Shay, Leah M Savitsky, Anna C Curtin, Emily M Huebner, Kimberly K Ma, Shani Delaney, Carlos Delgado, Adrienne Schippers, Jeff Munson, Paul S Pottinger, Seth Cohen, Santiago Neme, Lori Bourassa, Andrew Bryan, Alex Greninger, Keith R Jerome, Alison C Roxby, Erica Lokken, Edith Cheng, Kristina M Adams Waldorf, Jane Hitti. Low prevalence of SARS-CoV-2 among pregnant and postpartum patients with universal screening in Seattle, Washington. Clinical Infectious Diseases ciaa675, https://doi.org/10.1093/cid/ciaa675

Study 138 – 36 deaths among 484 pregnant women with Covid-19 in Brazil

Bulletin no 17 from the Brazilian Ministry of Health contains a special section on pregnant women with Covid-19 (click here or 2020-05-25—BEE17—Boletim-do-COE). The report is in Portugese. I’ve prepared an English translation of the pregnancy section using google translate Brazil MoH Covid 19 Bulletin 17 translation of pregnancy section. Citation: Ministério da Saúde, Secretaria de Vigilância em Saúde. Boletim Epidemiológico Especial da COVID-19 no Brasil. Número do boletim 17.  25 May 2020.

31 May update – study 137 added.

Study 137 – A patient with Covid-19 & an ectopic pregnancy

A 37-year-old woman tested positive for SARS-Cov2 and presented two days later with an ectopic pregnancy (click here or Ectopic_Pregnancy_During_Coronavirus_Disease_2019.97340). The authors discuss treatment options but give no further clinical details. Although the report is ambiguous, it is conventional in educational medical reports to present real cases unless stated otherwise. From author affiliations the patient was likely cared for in South Dakota or Texas. Citation: Hansen, Keith A; Stovall, Dale W. Ectopic Pregnancy During Coronavirus Disease 2019 (COVID-19), Obstet Gynecol: May 27, 2020 doi: 10.1097/AOG.0000000000003995 Removed 1 June 2020 because the peer review correspondence available here or aog_136_2_2020_05_18_hansen_20-1079_sdc1 makes clear that the case is hypothetical.

30 May update – study 136 added.

Study 136 – 158 cases from USA

Of 158 pregnant women with Covid-19, 34 had moderate or severe disease, 9 received ICU or step down care and 1 required intubation. There were no deaths (click here or Andrikopoulou Green Symptoms_and_Critical_Illness_Among_Obstetric.97341). No baby outcomes reported. Patients were cared for at NY Presbyterian/Columbia University Irving Medical Center, and at
New York-Presbyterian/Allen Hospital. Cases presumably overlap with those in studies 14, 27, 41 & 95. Citation: Andrikopoulou, Maria; Madden, Nigel; Wen, Timothy; Aubey, Janice J; Aziz, Aleha; Baptiste, Caitlin D;  Breslin, Noelle; D’Alton, Mary E; Fuchs, Karin; Goffman Dena; Gyamfi-Bannerman, Cynthia; Matseoane-Peterssen, Dara N; Miller, Russell S; Sheen, Jean-Ju; Simpson, Lynn L; Sutton, Desmond; Zork, Noelia; Friedman, Alexander M. Symptoms and Critical Illness Among Obstetric Patients With Coronavirus Disease 2019 (COVID-19) Infection, Obstet Gynecol May 27, 2020 – doi: 10.1097/AOG.0000000000003996

28 May update – studies 133 to 135 added

Study 135 –  50 cases from USA

Among 307 asymptomatic women tested on admission in labour, 50 were SARS CoV-2 positive (click here or Buckley Mount Sinai AJOGMFM). The women were tested between April 4 & 15, 2020, at two institutions within Mount Sinai Health System in New York. They therefore probably overlap with those in Study 119. Citation: Buckley A, Bianco A, Stone J, Universal testing of patients and their support persons for COVID-19 when presenting for admission to Labor and Delivery within the Mount Sinai Health System, Am J Obstet Gynecol MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100147.

Study 134 – 125 cases from USA

These authors report further details on 12 pregnant women with severe Covid 19, out of 125 in total (click here or McLaren AJOG PIIS0002937820305676). 7 were delivered by Caesarean, 2 vaginally, and 3 remain undelivered. No mothers died, although one remains in hospital. This is an update on study 113, and again the hospital is presumably Maimonides Medical Center, Brooklyn, New York. Citation: MCLAREN Jr. RA, LONDON V, ATALLAH F, MCCALLA S, HABERMAN S, FISHER N, STEIN JL, MINKOFF HL, Delivery For Respiratory Compromise Among Pregnant Women With COVID-19, Am J Obstet Gynecol (2020), doi: https://doi.org/10.1016/j.ajog.2020.05.035.

Study 133 – 3 cases identified by screening in Italy

By screening 533 women admitted for delivery for SARS-CoV2 between March 26th & April 1st in North Tuscany and Liguria, these authors identified 3 positives, who all gave birth without clinical problems (click here or PIIS0002937820305421). The women birthed in all the 6 hospitals of Azienda USL “Toscana Nord Ovest” (Tuscany), and Gaslini Children’s Hospital (Genoa, Liguria). They have therefore probably not previously been reported. Citation: Gagliardi L, Danieli R, Suriano G, Vaccaro A, Tripodi G, Rusconi F, Ramenghi LA, Universal SARS-CoV-2 testing of pregnant women admitted for delivery in two Italian regions. Am J Obstet Gynecol (2020), doi: https://doi.org/10.1016/j.ajog.2020.05.017.

27 May update – study 132 added (HT @janevandis)

Study 132 – 42 cases from USA

Of 782 women presenting for childbirth between April 2nd & 29th, 2020, 12 had already been diagnosed with Covid-19. Of the remainder 30/770 screened positive, 22 of whom were asymptomatic (click here orjama_campbell_2020_ld_200052). No clinical outcomes reported. No health care workers infected. Patients were cared for in 3 Yale New Haven Health hospitals in southern Connecticut. Citation: Katherine H. Campbell, Jean M. Tornatore, Kirsten E. Lawrence, Jessica L. Illuzzi, L. Scott Sussman, Heather S. Lipkind, Christian M. Pettker. Prevalence of SARS-CoV-2 Among Patients Admitted for Childbirth in Southern Connecticut. JAMA. Published online May 26, 2020. doi:10.1001/jama.2020.8904

26 May update – studies 129 to 131 added.

Study 131 – Anti-SARS-Cov2 IgA antibodies in breast milk of recovering women.

The authors of this not yet peer-reviewed preprint report anti SARS-Cov2 IgA antibodies in breast milk samples from 15 women previously infected with SARS-Cov2 (click here or 2020.05.04.20089995v1.full). No clinical details. The authors, mainly from Icahn School of Medicine at Mount Sinai, New York, report that they have recruited over 350 lactating women who have recovered from COVID-19.  Citation: Alisa Fox, Jessica Marino, Fatima Amanat, Florian Krammer, Jennifer Hahn-Holbrook, Susan Zolla-Pazner, Rebecca L Powell.  Evidence of a significant secretory-IgA-dominant SARS-CoV-2 immune response in human milk following recovery from COVID-19 doi: https://doi.org/10.1101/2020.05.04.20089995

Study 130 – Case report from Amsterdam Medical Centre, the Netherlands

A woman developed Covid-19 at 41 weeks gestation (Click here or ajh.25877). She also developed autoimmune throbocytopaenia. The baby was delivered by Caesarean. Citation: Man Wai Tang, Erfan Nur, Bart J. Biemond. Immune Thrombocytopenia during Pregnancy due to COVID-19. Am J Haematol. First published:23 May 2020 https://doi.org/10.1002/ajh.25877

Study 129 – 15 patients from USA

Of 213 admitted pregnant women screened by differential white blood count, 15 had Sars-Cov2 (click here or Duffy Green Lymphopenia_and_Severe_Acute_Respiratory_Syndrome.97345 (002)). Three required critical care for hypoxia. No other clinical details. From author affiliations patients were probably cared for in Beth Israel Deaconess Med Center, Harvard Med School, Boston, Mass. Citation: Duffy, Cassandra R. MD, MPH; Hart, Jessica M. MD; Modest, Anna M. PhD; Hacker, Michele R. ScD; Golen, Toni MD; Li, Yunping MD, MSc; Zera, Chloe MD, MPH; Shainker, Scott A. DO, MS; Mehrotra, Preeti MD, MPH; Zash, Rebecca MD; Wylie, Blair J. MD, MPH Lymphopenia and Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection Among Hospitalized Obstetric Patients, Obstetrics & Gynecology: May 19, 2020 – Volume Publish Ahead of Print – Issue – doi: 10.1097/AOG.0000000000003984

25 May update – studies 127-8 added.

Study 128 – 13 patients from North East Flanders, Belgium

Of 470 pregnant women screened, 13 tested positive for SARS-Cov2, 8 were asymptomatic 4 had mild upper airway symptoms, and one respiratory symptoms. None developed severe disease (click here or Ceulemans Flanders uog.22099 (1)) The hospitals caring for the four patients are unnamed but shown on a map. Citation: Ceulemans, D., Thijs, I., Schreurs, A., Vercammen, J., Lannoo, L., Deprest, J., Richter, J., De Catte, L. and Devlieger, R. (2020), Screening for COVID ‐19 at childbirth: does it deliver?. Ultrasound Obstet Gynecol. Accepted Author Manuscript. doi:10.1002/uog.22099

Study 127 – SARS-CoV-2 in human breastmilk

Breast milk from two nursing mothers infected with SARS-CoV-2 was tested. Samples from one woman were positive (click here or PIIS0140673620311818). Where the patients were cared for, was not reported. The authors came from Ulm in Germany. Citation: Rüdiger Groß, Carina Conzelmann, Janis A Müller, Steffen Stenger, Karin Steinhart, Frank Kirchhoff, Jan Münch. Detection of SARS-CoV-2 in human breastmilk. Lancet. Published online May 21, 2020 https://doi.org/10.1016/S0140-6736(20)31181-8

24 May update

Study 126 – The ISARIC report in the BMJ

Among 20,133 patients admitted to hospital with covid-19 in the UK, 100/1033 (10%) women of childbearing age, were reported as being pregnant (click here or bmj.m1985.full). This is similar to the estimated proportion of pregnant women in the community. Pregnancy was not associated with mortality. This is an update of study 68. Citation: Docherty Annemarie B, Harrison Ewen M, Green Christopher A, Hardwick Hayley E, Pius Riinu, Norman Lisa et al. Features of 20 133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study. BMJ 2020; 369 :m1985

23 May update – studies 121-125 added

Study 125 – 60 cases from Spain

Of 60 pregnant women with COVID-19 (click here or aogs.13921), 18 had pneumonia, 2 severely. One woman was admitted to ICU. No mothers died. Of 23 women delivered, 5 were by cesarean and 18 vaginally. Two delivered preterm. All 23 babies tested negative, and 21 were breast fed. Two babies were admitted to NICU for other reasons. No babies died. The patients were all were treated at Puerta de Hierro University Hospital Madrid, from March 14th to April 14th, 2020. Citation: Pereira, A., Cruz‐Melguizo, S., Adrien, M., Fuentes, L., Marin, E. and Perez‐Medina, T. (2020), Clinical course of Coronavirus Disease‐2019 (COVID‐19) in pregnancy. Acta Obstet Gynecol Scand. Accepted Author Manuscript. doi:10.1111/aogs.13921

Study 124 – 16 cases from USA

Fourteen patients delivered at term, 1 at 34 weeks, & 1 at 16-weeks (click here or aqaa089). No mothers admitted to ITU. No mother or baby deaths. No baby infections. The cases were identified  via a search of placental pathology records. Where the women were cared for is not recorded, but from author affiliation and a footnote probably includes Prentice Women’s Hospital, Northwestern Memorial Hospital and Feinberg School of Medicine, Northwestern University, Chicago. Citation: Elisheva D Shanes, Leena B Mithal, Sebastian Otero, Hooman A Azad, Emily S Miller, Jeffery A Goldstein. Placental Pathology in COVID-19, Am J Clin Pathol. aqaa089, https://doi.org/10.1093/ajcp/aqaa089 Published: 22 May 2020

Study 123 – 16 cases from Michigan

Two patients received oxygen via nasal cannula, none were admitted to ITU. There were 8 vaginal births (one preterm) and 2 Caesareans. No babies were infected. Six women remain undelivered    (click here or Qadri Michigan Pregnancy affected by SARS CoV 2 infection a flash report…). Citation: Farnoosh Qadri & Federico Mariona (2020) Pregnancy affected by SARS-CoV-2 infection: a flash report from Michigan. J Mat-Fetal & Neonatal Med. DOI: 10.1080/14767058.2020.1765334

Study 122 – Response of Northwell Health to Covid-19 in pregnancy

A detailed description of how a large multi-hospital network in the USA organised itself to care for women with Covid-19 in pregnancy (click here or Rochelson [16193997 – Journal of Perinatal Medicine]). No patient numbers or details. Citation: Burton Rochelson, Michael Nimaroff, Adriann Combs, Benjamin Schwartz, Natalie Meirowitz, Nidhi Vohra, Victor R. Klein, Orlando Santandreu, Mitchell Kramer, Navid Mootabar, Eli Serur, Lisa Spiryda, Scott Berlin. Frank Chervenak. The Care of Pregnant Women During the COVID-19 Pandemic – Response of a Large Health System in Metropolitan New York. J Perinat Med. 2020 May 20;/j/jpme.ahead-of-print/jpm-2020-0175/jpm-2020-0175.xml. doi: 10.1515/jpm-2020-0175. Online ahead of print.

Study 121 – One week’s screening in Los Angeles.

The Cedars-Sinai Medical Center, Los Angeles, California, USA, screened 82 pregnant women over a one week period (click here or Severe_Acute_Respiratory_Syndrome_Coronavirus_2.97344). None of the 80 asymptomatic women tested positive but one of two symptomatic ones did. No further details reported. Citation: Mariam Naqvi, Richard M Burwick, John A Ozimek, Naomi H Greene, Sarah J Kilpatrick, Melissa S Wong. Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Universal Testing Experience on a Los Angeles Labor and Delivery Unit, Obstetrics & Gynecology: May 19, 2020 – Volume Publish Ahead of Print – Issue – doi: 10.1097/AOG.0000000000003987

21 May update – studies 116-120 added.

Study 120 – 191 women from the Netherlands Covid-19 registry

This 14 May update of NethOSS (click here), accessed 21 May 2020, contains the following. 6/156 women with brief additional details were admitted to intensive care; one remains there. One mother had a molar pregnancy and one a miscarriage. 47 women have given birth, 16 by Caesarean. 109 pregnancies are ongoing. No mother or baby has died. No babies were infected. Citation: See Studies 42 and 46. Available here. Accessed 21 May. Note: we probably missed some intermediate updates from this registry.

Study 119 – 24 cases identified by screening in New York

24/155 asymptomatic women screened for SARS-COV-2 prior to a planned delivery, tested positive (click here or Bianco Green Testing_of_Patients_and_Support_Persons_for.97342). All their newborns were tested and none were positive. No maternal outcomes were reported. The patients were all cared for in the Mount Sinai Health system between April 4th and 15th. From author affiliations this was Icahn School of Medicine at Mount Sinai Hospital. These cases may therefore overlap with some in study 86. Citation: Bianco, Angela; Buckley, Ayisha B; Overbey, Jessica; Smilen, Scott; Wagner, Brian; Dinglas, Cheryl; Loudon, Holly; Garely, Alan; Brodman, Michael; Stone, Joanne. Testing of Patients and Support Persons for Coronavirus Disease 2019 (COVID-19) Infection Before Scheduled Deliveries, Obstetrics & Gynecology: May 19, 2020 – Volume Publish Ahead of Print – Issue – doi: 10.1097/AOG.0000000000003985

Study 118 – a maternal death from USA

A 36-year-old woman developed Covid-19 at 37 weeks gestation (click here or Vallejo Green A_Postpartum_Death_Due_to_Coronavirus_Disease_2019.97350). Within three hours of admission she required intubation and Caesarean, and she died within 36 hours. The baby tested negative and survived. The hospital is not named, and she was not transferred. From the author affiliations it was either Dept OBGYN, Urban Health Plan, Inc., Bronx, or Division of Maternal-Fetal Med, Dept OBGYN, Weill Cornell Medicine, New York. Citation: Victoria Vallejo, John G. Ilagan. A Postpartum Death Due to Coronavirus Disease 2019 (COVID-19) in the United States. Obstet Gynecol 2020;00:1–4 DOI: 10.1097/AOG.0000000000003950

Study 117 – 77 cases from Italy

From Feb 23 to March 28th, 14/77 women with Covid-19 were severely affected, and one required ECMO (click here or Savasi Green Clinical_Findings_and_Disease_Severity_in.97347). 57 gave birth, 22 by Caesarean. Four newborns tested positive for SARS-COV-2, but none had symptoms. 20 pregnancies are ongoing. No mothers or babies died. The 12 hospitals L. Sacco (Milan), Mangiagalli (Milan), S. Gerardo MBBM Foundation (Monza), Papa Giovanni XXIII (Bergamo), and San Matteo (Pavia) and the hospitals of Padua, Florence, Lecco, Trento, Modena, Seriate and Piacenza. These are the same hospitals as studies 32 & 64. The patients probably overlap. Citation: Savasi, Valeria M. MD, PhD; Parisi, Francesca MD, PhD; Patanè, Luisa MD; Ferrazzi, Enrico MD; Frigerio, Luigi MD, PhD; Pellegrino, Antonio MD; Spinillo, Arsenio MD; Tateo, Saverio MD; Ottoboni, Mariacristina MD; Veronese, Paola MD, PhD; Petraglia, Felice MD; Vergani, Patrizia MD; Facchinetti, Fabio MD; Spazzini, Donata MD; Cetin, Irene MD, PhD Clinical Findings and Disease Severity in Hospitalized Pregnant Women With Coronavirus Disease 2019 (COVID-19), Obstetrics & Gynecology: May 19, 2020 – Volume Publish Ahead of Print – Issue – doi: 10.1097/AOG.0000000000003979

Study 116 – A “universal testing in pregnancy” series from Chicago, USA

Northwestern Memorial Hospital, tested a consecutive series of 635 pregnant women admitted between April 8th & 28th, 2020. Of these 23 (3.6%) tested positive for SARS-CoV-2, of whom 10 (44%) were asymptomatic on presentation (click here or Miller NorthWestern Clinical_Implications_of_Universal_Severe_Acute.9734…). No maternal or baby outcomes were reported. Citation: Miller, Emily S. MD, MPH; Grobman, William A. MD, MBA; Sakowicz, Allie MS; Rosati, Jessica MSN, RN; Peaceman, Alan M. MD Clinical Implications of Universal Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Testing in Pregnancy, Obstetrics & Gynecology: May 19, 2020 – Volume Publish Ahead of Print – Issue – doi: 10.1097/AOG.0000000000003983

20 May update Studies 113 (HT Fred Peret. We’d missed it!) to 115 added

Study 115 – Case report of Covid-19 & severe pre-eclampsia, USA

A 26-year-old with Covid-19 at 37 weeks gestation also had severe pre-eclampsia (click here or AJOGMFM-20-1073 ). She was treated with magnesium sulphate and delivered vaginally. The baby tested negative. Both recovered. From author affiliations likely cared for at Stanford University Hospital. Citation: Joudi N, Henkel A, Lock WS, Lyell D, Preeclampsia Treatment in SARSCoV-2, American Journal of Obstetrics & Gynecology MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100146.

Study 114 – 22 women from Italy

Of 22 women with Covid-19 in pregnancy two neonates tested positive, one born vaginally and one by caesarean. Both did well. Their placental histology is described (click here or AJOGMF-20-1112). No other mother or baby details are given. The women were cared for between March 5, & April 21, 2020 at Papa Giovanni XXIII Hospital, Bergamo, in the Lombardy region, so the women were probably also reported in study 32 & study 64. Citation: Patanè L, Morotti D, Giunta MR, Sigismondi C, Piccoli MG, Frigerio L, Mangili G, Arosio M, Cornolti G, Vertical transmission of COVID-19: SARS-CoV-2 RNA on the fetal side of the placenta in pregnancies with COVID-19 positive mothers and neonates at birth, American Journal of Obstetrics & Gynecology MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100145.

Study 113 – 68 SARS-Cov-2 positive pregnant women from New York, USA

46 had Covid-19 and a further 22 asymptomatic women tested positive for SARS-Cov-2 (click here or s-0040-1712164). 12 women had severe disease, one requiring ventilation. There was one intrauterine death at 17 weeks but otherwise no mothers or babies died. All babies tested negative. 12 pregnancies are ongoing.  Women were cared for at a tertiary care hospital in Brooklyn, from March 15 to April 15, 2020. From author affiliations probably Maimonides Medical Center, Brooklyn, NY. If so, they have not been previously reported.  Citation: Viktoriya London, Rodney McLaren Jr., Fouad Atallah, Catherine Cepeda, Sandra McCalla, Nelli Fisher, Janet L. Stein, Shoshana Haberman, Howard Minkoff. The Relationship between Status at Presentation and Outcomes among Pregnant Women with COVID-19. Am J Perinatol. DOI https://doi.org/10.1055/s-0040-1712164. ISSN 0735-1631. Online April 27, 2020

19 May update – studies 108 to 112 added.

Study 112 – Case report from USA

A 35-year-old developed Covid-19 at 22 weeks gestation requiring intubation & ventilation (click here or  1-s2.0-S2214911220300515-main). She recovered and the pregnancy is ongoing. U Tennessee Health Science Center, Nashville, Tennessee, has not previously reported cases. Citation: J. Anderson, J. Schauer, S. Bryant, et al., The use of convalescent plasma therapy and remdesivir in the successful management of a critically ill obstetric patient with novel coronavirus 2019 infection: A case report. Case Rep Women’s Health (2020), https://doi.org/10.1016/j.crwh.2020.e00221

Study 111 – Case report from USA

A 39-year-old woman, with IVF twins developed Covid-19 at 27 weeks of gestation (click here or 1-s2.0-S2214911220300503-main). She required ventilation and then an emergency classical Cesarean section a the bedside due to rapid deterioration.  She recovered. One twin was infected, but both survived. She was cared for in Saint Barnabas Medical Center, Livingston, New Jersey, which has not previously reported a case.  Citation:  H. Mehta, S. Ivanovic, A. Cronin, et al., Novel coronavirus related acute respiratory distress syndrome in a patient with twin pregnancy: A case report. Case Rep Women’s Health (2020), https://doi.org/10.1016/j.crwh.2020.e00220

Study 110 – Case report from Thailand

A 43-year-old with mild Covid-19 at 18 weeks gestation (click here or Panichaya Thailand PIIS0301211520303134). Amniocentesis done a week earlier showed trisomy 21, & the pregnancy was terminated. Placental & fetal swabs were negative. The hospital was not named. Citation: Panichaya P, Thaweerat W, Uthaisan J. Prolonged viral persistence in COVID-19 second trimester pregnant patient, Eur J Obstet & Gynecology & Reprod Biol (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.05.030

Study 109 – 4 women from Italy

Four women with Covid-19 recovered and later delivered healthy term neonates (click here or Acta BioMed Parma 9743-Article Text-49126-2-10-20200514). They were cared for in Parma Hospital, in the Emilia-Romagna (not Lombardy) region of Italy. Citation: Serafina Perrone, Michela Deolmi, Maurizio Giordano, Tiziana D’Alvano, Lucia Gambini, Mara Corradi, Tiziana Frusca, Tullio Ghi, Susanna Esposito. Report of a series of healthy term newborns from convalescent mothers with COVID-19. Acta Biomed 2020; Vol. 91, N. 2: 251-255 DOI: 10.23750/abm.v91i2.9743

Study 108 – 27 cases from China

These 27 women with Covid-19 in pregnancy included 4 early pregnancies. They delivered 24 babies (1 set of twins) (click here or Yang Wuhan arpa.2020-0232-sa). They were cared for at “Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology in Wuhan” between Jan 20 & Mar 19, 2020.  Assuming this is Central Hospital of Wuhan, grid.440160.7 these cases likely overlap with studies 39 and 73. They are probably also included in studies 55 & 57. Citation: Hui Yang, Bin Hu, Sudong Zhan, Li-ye Yang, Guoping Xiong. Effects of SARS-CoV-2 infection on pregnant women and their infants: A retrospective study in Wuhan, China. Arch Pathol Lab Med. In press. doi: 10.5858/arpa.2020-0232-SA

18 May update – studies 105 to 107 added

Study 107 – Maternal death in Birmingham, UK

A 29-year-old woman with severe Covid-19 was delivered by Caesarean section at Birmingham Heartlands Hospital at 31 weeks gestation (click here or Mat Death Bham BrJH bjh.16849). The baby tested negative and is doing well. The mother initially improved and was extubated on day 2 post natal. However on day 6 she developed basilar artery thrombosis, and she died on day 7. Case presumably included in study 92 UKOSS. Citation: Ahmed, I., Azhar, A., Eltaweel, N. and Tan, B.K. (2020), First Covid‐19 maternal mortality in the UK associated with thrombotic complications. Br J Haematol. Accepted Author Manuscript. doi:10.1111/bjh.16849

Study 106 – 2 cases from Reading, UK

Two women with severe Covid-19 were treated at the Royal Berkshire Hospital (click here or Cooke Reading PIIS0301211520302761 (002). Both were preterm (28+4, 28+6 days) and required Caesarean for deteriorating maternal condition. Both mothers recovered. One baby had a perforated bowel but both eventually recovered. Presumably both cases were included in study 92 UKOSS. Citation: Cooke WR, Billett A, Gleeson S, Jacques A, Place K, Siddall J, Walden A, Soulsby K. SARS-CoV-2 infection in very preterm pregnancy: experiences from two cases, Eur J Obstet Gynecol & Reprod Biol (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.05.025

Study 105 – 12 cases from from Hospital Pedro Hispano, Portugal

All 123 pregnant women admitted to Hospital Pedro Hispano in Porto between March 25 & April 15 were tested for SARS-CoV-2. 12 were positive, of whom 11 were asymptomatic, 10 have delivered, 6 by cesarean section and 4 vaginally. There was one set of twins. There were no maternal complications and all the newborns tested negative (click here or Doria N Portugal PIIS0301211520303122 (002) This series may include the cases in study 74 & study 94. Citation: D´oria M, Peixinho C, Laranjo M, Varejao AM, Silva PT. Covid-19 during pregnancy: a case series from an universally tested population from the north of Portugal. Eur J Obstet Gynecol & Reprod Biol (2020). doi: https://doi.org/10.1016/j.ejogrb.2020.05.029

16 May update – Study 104 added

Study 104 – ICNARC 15th May update

The 15th May ICNARC update (click here or ICNARC COVID-19 report 2020-05-15.pdf) contains 23 currently, and 32 recently, pregnant women critically ill with Covid-19. Of these 9 and 16 respectively had received advanced respiratory support.

Study 103 – Case report from Toronto, Ontario, Canada

A 40-year-old woman developed Covid-19 at 35 weeks gestation and was delivered by Caesarean (click here or cmaj.200821.full). The baby tested positive on the day of birth, breast fed and had some minor feeding difficulties, but eventually thrived. The mother is acknowledged to be one of the cases reported in study 48. Citation: Maksim Kirtsman, Yenge Diambomba, Susan M. Poutanen, Ann K. Malinowski, Evangelia Vlachodimitropoulou, W. Tony Parks, Laura Erdman, Shaun K. Morris, Prakesh S. Shah. Probable congenital SARS-CoV-2 infection in a neonate born to a woman with active SARS-CoV-2 infection  CMAJ 2020. doi: 10.1503/cmaj.200821; early-released May 14, 2020 (HT Jon Dorling & Don Sharkey).

Study 102 – 46 patients from Washington State, USA

Of 46 pregnant women with SARS-CoV-2, 43 were symptomatic, 7 hospitalized, 6 categorised as severe, and 1 admitted to ICU (click here or Lokken-AJOG). Eight women delivered, 5 vaginal, 3 Caesarean. All mothers survived. There were 7 livebirths & one stillbirth at 38 weeks. That fetus tested negative.  One baby was preterm. No further baby details were given. 38 pregnancies are ongoing. The women were cared for in 16 hospitals: University of Washington Hospital system (Montlake, Northwest, & Harborview campuses), Swedish Medical Center (First Hill, Ballard, Issaquah and Edmonds campuses), University of Washington Valley Medical Center, MultiCare Health System (Auburn Medical Center, Covington Medical Center, Tacoma General Hospital, Good Samaritan Hospital, Valley Hospital and Deaconess Hospital), Evergreen Health Medical Center, and PeaceHealth-St. Joseph’s Medical Center. Citation: Erica M. LOKKEN et al. Clinical Characteristics of 46 Pregnant Women with a SARS-CoV-2 Infection in Washington State. Am J Obstet Gynecol. 2020 May 19 doi: 10.1016/j.ajog.2020.05.031 [Epub ahead of print] PMCID: PMC7234933 PMID: 32439389

Study 101 – Case report from Iran

A 33-year-old woman with severe Covid-19 at 34 weeks gestation was treated at Imam Reza hospital of Tabriz (click here or Taghizadieh Iran 1-s2.0-S2213007120302306-main). She required intubation, ventilation, renal dialysis & delivery by Caesarean. The baby tested negative & was in good health. The mother remains intubated but is recovering. The clinical details differ sufficiently from the two women who survived in study 67 to make it likely that this is a previously unreported case. Citation: Taghizadieh A, Mikaeili H, Ahmadi M, Valizadeh H, Acute kidney injury in pregnant women following SARS-CoV-2 infection: A case report from Iran, Respiratory Medicine Case Reports (2020), doi: https://doi.org/10.1016/j.rmcr.2020.101090.

May 15 update – study 100 added

Study 100 – Case report at 26 weeks (& 5 other cases) from Belgium

A woman was diagnosed with Covid-19 six days after giving birth at 26 weeks by Caesarean because of pre-eclampsia & HELLP syndrome at Cliniques Universitaires Saint Luc, in Brussels, Belgium, (click here or Lancet Piersigilli PIIS2352464220301401). The baby tested positive for SARS-CoV-2 but but otherwise behaved as expected for her gestational age. Subsequently five further women with Covid-19 delivered in the same hopsital. All babies were negative. Only one required NICU for unrelated reasons.  Citation: Fiammetta Piersigilli, Katherine Carkeek, Catheline Hocq, Bénédicte van Grambezen, Corinne Hubinont, Olga Chatzis, Dimitri Van der Linden, Olivier Danhaive COVID-19 in a 26-week preterm neonate. Lancet Child Adolesc Health 2020 Published Online May 7, 2020 https://doi.org/10.1016/S2352-4642(20)30140-1

May 14th update – studies 97-99 added

Study 99 – Placental pathology of 20 cases from Weill Cornell Medical Center

Of 20 women with Covid-19, five delivered by Caesarean and 15 vaginally (click here or Baergen Ped Pathol 1093526620925569). Three gave birth preterm and there was one set of twins. No baby outcomes are reported. These may overlap with other New York cases. Citation: Baergen, R. N., & Heller, D. S. (2020). Placental Pathology in Covid-19 Positive Mothers: Preliminary Findings. Pediatric and Developmental Pathology, 23(3), 177–180. https://doi.org/10.1177/1093526620925569

Study 98 – Ulcerative Colitis & COVID-19 in pregancy, USA

A 26-year-old woman with known ulcerative colitis developed Covid-19 very early in pregnancy (fetal heartbeat & yolk sac on scan). She did not require admission to ITU or ventilation, and recovered, but the pregnancy miscarried (click here or UC and COVID pregnancy IBD izaa109 (1). She was treated at NY Langone so may also be included in studies 85 & 86. Citation: Melissa H Rosen, MD, Jordan Axelrad, MD, MPH, David Hudesman, MD, David T Rubin, MD, Shannon Chang, MD, Management of Acute Severe Ulcerative Colitis in a Pregnant Woman With COVID-19 Infection: A Case Report and Review of the Literature, Inflammatory Bowel Diseases, , izaa109, https://doi.org/10.1093/ibd/izaa109

Study 97 – Case report from Strasbourg, France

A 21 year old with severe Covid-19 at 23 weeks gestation (click here or Case rep Strasbourg PIIS0301211520302736) was admitted to ICU, treated with noninvasive ventilation and positional therapy and recovered. The pregnancy is ongoing. Citation: Vibert F, Kretz M, Thuet V, Barthel F, De Marcillac F, Deruelle P, Lecointre L, Prone positioning and high-flow oxygen improved respiratory function in a 25-week pregnant woman with COVID-19. European Journal of Obstetrics & Gynecology and Reproductive Biology (2020). doi: https://doi.org/10.1016/j.ejogrb.2020.05.022

May 13th update – studies 95 & 96 added (HT Shakila Thangaratinam).

Study 96 – another report of 5 cases from NY Presbyterian, Cornell, USA

The same 5 cases as study 95 (click here). Citation: J. Justin Mulveya, Cynthia M.Magro, Lucy X Ma, Gerard J Nuovo, Rebecca N Baergen. Analysis of complement deposition and viral RNA in placentas of COVID-19 patients. Annals of Diagnostic Pathology Volume 46, June 2020, https://doi.org/10.1016/j.anndiagpath.2020.151530

Study 95 – placental pathology of the first 5 cases from NY Presbyterian, Cornell, USA

Five patients with Covid-19, one delivered by Caesarean, & four vaginally (click here). All resulted in healthy, term deliveries, but no further baby details reported. All mothers recovered. Discussion, “at the time of writing these patients represent 100% of the confirmed COVID-19 deliveries at New York Presbyterian Hospital, Cornell Campus“. A different hospital from NY Presbyterian Allen (studies 27 & 41). Citation: Justin Mulveya, Cynthia M.Magro, Lucy X Ma, Gerard J Nuovo, Rebecca N Baergen. A mechanistic analysis placental intravascular thrombus formation in COVID-19 patients. Annals of Diagnostic Pathology Volume 46, June 2020, https://doi.org/10.1016/j.anndiagpath.2020.151529

May 12 Update – studies 93 & 94 added

Study 94 – Case report from Portugal

A 31-year-old woman with Covid-19 at 38 weeks had a vaginal birth in a level 3 hospital in Porto (click here or PIIS030121152030258X). The baby was isolated and not infected. Not the same case as study 74 because delivered vaginally. Citation: Polonia-Valente R, Moucho M, Tavares M, Vilan A, Montenegro N, Rodrigues T. Vaginal delivery in a woman infected with SARS-CoV-2 – the first case reported in Portugal. European Journal of Obstetrics & Gynecology & Reproductive Biology (2020), doi: https://doi.org/10.1016/j.ejogrb.2020.05.007

Study 93 – 9 cases from UK

Out of 9 hospital cases, 1 was preterm, 1 had a vaginal birth, and 1 baby was infected (click here or Govind EJOG London PIIS0301211520302578). Cared for in North Middlesex Hospital, London. Presumably all 9 included in study 92. Citation: A. Govind, et al., Re: Novel Coronavirus COVID-19 in late pregnancy: Outcomes of first nine cases in an inner city London hospital, Eur J Obstet Gynecol (2020), https://doi.org/10.1016/j.ejogrb.2020.05.004

May 11th update. Keelin’s found study 91’s figures. And study 92, the first report from UKOSS, added.

Study 92 – 427 cases from UK

The first report (May 11th 2020) from the UK Obstetric Surveillance System (UKOSS) Covid-19 registry of 427 pregnant women admitted to hospital with confirmed Sars-CoV-2 from all 194 UK obstetric units (click here). Twice the size of all previous studies combined. No overlaps. [important]

9 June update.

Study 92a Published version in BMJ online (click here or bmj.m2107.full). Citation: Knight Marian, Bunch Kathryn, Vousden Nicola, Morris Edward, Simpson Nigel, Gale Chris et al. Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study BMJ 2020; 369 :m2107

May 10th update – Studies 88 to 91 added.

Study 91 – Alleged visualisation of the SARS-Cov-2 virus invading the placenta, USA

Case report of a woman, aged 40, with severe Covid-19 requiring ventilation, and later delivery at 28 weeks gestation by Caesarean section (click here or ALGARROBA). The mother recovered and was discharged on day 10. The baby tested negative. The paper is missing its figures, but there’s a video clip (click here). Update 11th May (click here for the figures). Author affiliations suggest she was cared for at NYU Langone Health, Winthrop Hospital, New York. Citation: Gabriela N. ALGARROBA,, Patricia REKAWEK, Sevan A. VAHANIAN, Poonam KHULLAR, Thomas PALAIA, Morgan R. PELTIER, Martin R. CHAVEZ, Anthony M. VINTZILEOS. Visualization of SARS-CoV-2 virus invading the human placenta using electron microscopy. Am J Obstet Gynecol. in press. 

Study 90 – ICNARC 8th May update

The 8th May update (click here or ICNARC COVID-19 report 2020-05-08.pdf) contains 21 currently, and 30 recently, pregnant women critically ill with Covid-19. Of these 9 and 16 respectively had received advanced respiratory support. Excluded from running totals.

Study 89 – Case report from San Fancisco, USA

A 34-year-old woman developed Covid-19 at at 28 weeks of gestation (click here or Acute_Respiratory_Distress_Syndrome_in_a_Preterm.97348). Her deteriorating condition necessitated delivery by Caesarean section. She required 10 days mechanical ventilation. Neonatal swabs for SARS-CoV-2 and COVID-19 immunoglobulin (Ig) G and IgM were negative. Citation: Blauvelt CA, Chiu C, Donovan AL, Prahl M, Shimotake TK, George RB, Schwartz BS, Farooqi NA, Ali SS, Cassidy A, Gonzalez JM, Gaw SL. Acute Respiratory Distress Syndrome in a Preterm Pregnant Patient With Coronavirus Disease 2019 (COVID-19). Obstet Gynecol. 2020 May 8. doi: 10.1097/AOG.0000000000003949. [Epub ahead of print]

Study 88 – 13 pregnant women with Covid-19 in intensive care in Sweden

Of 53 women aged 20-45 years with SARS-CoV-2 reported to the Swedish Intensive Care Registry, 13 were either pregnant or <1 week postpartum (click here or ). Citation: Collin J, Byström E, Carnahan A, Ahrne M. Pregnant and postpartum women with SARS-CoV-2 infection in intensive care in Sweden. Acta Obstet Gynecol Scand. 2020 May 9. doi: 10.1111/aogs.13901. [Epub ahead of print]

May 9th update – Study 87 added

Study 87 – Case report from USA

A 36-year-old developed severe Covid-19 at 23 weeks gestation, and required 7 days ventilation (click here or 1-s2.0-S2214911220300473-main DETROIT). She survived, and the pregnancy is ongoing. She was treated at the Henry Ford Hospital, Detroit. Citation: L. Hong, N. Smith, M. Keerthy, et al., Severe COVID-19 infection in pregnancy requiring intubation without preterm delivery: A case report. Case Reports in Women’s Health (2020), https://doi.org/10.1016/j.crwh.2020.e00217

May 8th update – studies 84-86 added

Study 86 – 64 pregnant women with severe Covid-19 in 12 US hospitals

Of 64 pregnant women with severe (n=44) or critical (n=20) Covid-19, one had a cardiac arrest, 19 were intubated, none had ECMO, and 13 remain hospitalized, but none have died (click here or COVID_CC_post_review_04302020). Of the 32 who have given birth 24 were delivered by Caesarean. One baby was infected, but no babies died. The women had been admitted to 12 unnamed hospitals between March 5 & April 20. From the author affiliations the hospitals probably include Pennsylvania, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia; Perelman School of Medicine, University of Pennsylvania; St. Luke’s University Health Network, Bethlehem; Crozer Chester Medical Center, Chester; Einstein Healthcare Network, Philadelphia. New York Montefiore Medical Center/Albert Einstein College of Medicine, Bronx; NY University Langone Medical Center; Icahn School of Medicine at Mount Sinai; New Jersey Rutgers Robert Wood Johnson Medical School, New Brunswick; Saint Barnabas Medical Center, Livingston; Ohio TriHealth-Good Samaritan Hospital, Cincinnati. Citation: Rebecca A.M. Pierce-Williams, Julia Burd, Laura Felder, Rasha Khoury, Peter S. Bernstein, Karina Avila, Christina A. Penfield, Ashley S. Roman, Chelsea A. DeBolt, Joanne L. Stone, Angela Bianco, Adina R. Kern-Goldberger, Adi Hirshberg, Sindhu K. Srinivas,, Jenani S. Jayakumaran, Justin S. Brandt, Hannah Anastasio, Meredith Birsner, Devon S. O’Brien, Harish M. Sedev, Cara D. Dolin, William T. Schnettler, Anju Suhag, Shabani Ahluwalia, Reshama S. Navathe, Adeeb Khalifeh, Kathryn Anderson, Vincenzo Berghella. Clinical course of severe and critical COVID-19 in hospitalized pregnancies: a US cohort study. Am J Obstet Gynecol. In press.

Study 85 – 32 women from New York, USA

Between March 1 & April 20, 32 women with Covid-19 gave birth at NYU Langone Health. Eleven had placental or membrane swabs tested of which 3 were positive (click here or study). Of the 11 women 3 women with critical, and one with severe disease, were delivered by caesarean. All the rest, one severe disease, the remainder mild, gave birth vaginally. None of the infants tested positive or demonstrated symptoms of COVID-19 infection. Citation: Penfield CA, Brubaker SG, Limaye MA, Lighter J, Ratner AJ, Thomas KM, Meyer JA, Roman AS. Detection of severe acute respiratory syndrome coronavirus 2 in placental and fetal membrane samples. Am J Obstet Gynecol MFM. 2020 Aug;2(3):100133. doi: 10.1016/j.ajogmf.2020.100133. Epub 2020 May 8. PMID: 32391518; PMCID: PMC7205635.

Study 84 – Twins from St Thomas’s, London, UK

A woman with twins developed Covid-19 at 32 weeks (click here or Twins abruption STH london AJOGMFM-20-1053).  She was delivered by Caesarean section due to suspected abruption. Both babies tested negative for COVID-19. Citation: Katy Kuhrt, Jess McMicking, Surabhi Nanda, Catherine Nelson Piercy, Andrew Shennan. Placental abruption in a twin pregnancy at 32 weeks’ gestation complicated by COVID-19, without vertical transmission to the babies. Am J Obstet Gynecol in press.

May 7th update – studies 82 & 83 added. Study 81 comment revised; this is probably the same ECMO case as previously reported in studies 3 and 57.

Study 83 – 82 women in USA

Of 82 pregnant women with Covid-19, admitted to seven hospitals within an unnamed large hospital group in New York State, eight (9.8%) were admitted to intensive care (click here or L20-081), a similar proportion to non-pregnant women of reproductive age. No clinical outcomes are reported. Study 49 by the same group, reporting Covid-19 admissions in an unnamed 14 hospital group, is cited. Although not explicitly stated, it seems likely that the cases overlap. Citation: Matthew J. Blitz, Amos Grünebaum, Asma Tekbali, Eran Bornstein, Burton Rochelson, Michael Nimaroff, Frank A. Chervenak. Intensive Care Unit Admissions for Pregnant and Non-Pregnant Women with COVID-19. Am J Obstet Gynecol in press. 

Study 82 – 9 screen-positive women at The Portland, London, UK

Between March 27 & April 20th, The Portland, a private hospital in London, performed planned Caesareans for 129 NHS patients.  All were screened for SARS-CoV2, and 9 (7%) were positive, of whom only one was symptomatic (click here or SARS-CoV-2_and_pregnancy_letter_line_nbrs).  None of the positive asymptomatic women developed COVID-19 symptoms. The outcome of the symptomatic woman was not reported. All babies were well at birth and at discharge. Citation: Khalil A, Hill R, Ladhani S, Pattisson K, O’Brien P. Severe acute respiratory syndrome coronavirus 2 in pregnancy: symptomatic pregnant women are only the tip of the iceberg. Am J Obstet Gynecol. 2020;223(2):296-297. doi:10.1016/j.ajog.2020.05.005

May 6th update – study 79 (HT Shakila Thangaratinam) & studies 80 & 81 added.

Study 81 – Case report from China

A 31 year old woman developed Covid-19 at 35 weeks gestation (click here, or ijgo.13189). The mother’s condition deteriorated rapidly, requiring ventilation, and later ECMO. The baby was delivered by emergency caesarean but died within two hours. The mother survived. This is the second pregnant woman requiring ECMO reported from China. Zhongshan People’s Hospital disambiguates as grid.476868.3 and no patients from Zhongshan have previously been reported, not in Study 3, nor in studies 55 or 57. This case is therefore likely original. Citation: Li J, Wang Y, Zeng Y, Song T, Pan X, Jia M, He F, Hou L, Li B, He S, Chen D. Critically ill pregnant patient with COVID-19 and neonatal death within two hours of birth. Int J Gynaecol Obstet. 2020 May 5. doi: 10.1002/ijgo.13189.

Revised comment 7 May. The city of Zhongshan is in the province of Guangdong. Study 3, which initially mentioned “patient 6”, a 31 year old woman at 34 weeks on ECMO, whose baby had died, included one patient from Guangdong. Study 57 described a 32-year-old woman at 35 weeks from Zhongshan, Guangdong whose baby had died soon after birth. At the time of the report that woman had been weaned off ECMO but remained an inpatient. Despite the minor inconsistencies in maternal and gestational ages, it is likely that all three reports refer to the same woman. If so there has only been one pregnant woman with Covid-19, treated with ECMO, and reported from China. She survived.

Study 80 – 13 women from China

These 13 women were cared for in Renmin Hospital of Wuhan University, Wuhan (click here for abstract. Full text not yet available). Citation: Wu Y, Liu C, Dong L, Zhang C, Chen Y, Liu J, Zhang C, Duan C, Zhang H, Mol BW, Dennis CL, Yin T, Yang J, Huang H. Coronavirus disease 2019 among pregnant Chinese women: Case series data on the safety of vaginal birth and breastfeeding. BJOG. 2020 May 5. doi: 10.1111/1471-0528.16276. [Epub ahead of print]

Study 79 – Case report from Italy

A 28-year-old woman with Covid-19 gave birth vaginally at 37 weeks (click here or PIIS0301211520302025). The baby tested positive but was otherwise well. The baby was born at Sant’Anna Hospital, Turin. Turin is outside Lombardy; this case was not included in studies 32 and 64. Citation: A. Carosso, et al., Pre-labor anorectal swab for SARS-CoV-2 in COVID-19 pregnant patients: is it time to think about it? Eur J Obstet Gynecol (2020), https://doi.org/10.1016/j.ejogrb.2020.04.023

May 5th update – study 78 added

Study 78 – Case report from Italy

A 23 weeks pregnant woman with Covid-19 admitted on 10th March to Fondazione Policlinico Universitario Agostino Gemelli, Rome(click here or PIIS0002937820304683). Obstetric ultrasound revealed a normally grown fetus with normal amniotic fluid and Doppler parameters. No further pregnancy details. Likely to be one of the women with ongoing pregnancy in study 76Citation: Inchingolo R, Smargiassi A, Moro F, Buonsenso D, Salvi S, Del Giacomo P, Scoppettuolo G, Demi L, Soldati G, Testa AC, The Diagnosis of Pneumonia in a Pregnant Woman with COVID-19 Using Maternal Lung Ultrasound. American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.04.020.

May 4th update – Studies 76 & 77added

Study 77 – ICNARC 1st May update

The 1st May update (click here or ICNARC COVID-19 report 2020-05-01) contains 20 currently, and 27 recently, pregnant women critically ill with Covid-19. Of these 7 and 14 respectively had received advanced respiratory support. Excluded from running totals.

Study 76 – 7 cases from Fondazione Policlinico Universitario Agostino Gemelli  Rome, Italy

Of seven pregnant women with Covid-19, one miscarried at 7 weeks, 4 pregnancies are ongoing, and 2 were delivered, both by Caesarean (click here or  buonsenso Rome AJP s-0040-1710541). Both babies had many swabs tested but were well. Citation: Danilo Buonsenso, Simonetta Costa, Maurizio Sanguinetti, Paola Cattani, Brunella Posteraro, Simona Marchetti, Brigida Carducci, Antonio Lanzone, Enrica Tamburrini, Giovanni Vento, Piero Valentini. Neonatal Late Onset Infection with Severe Acute Respiratory Syndrome Coronavirus 2. Am J Perinatol https://doi.org/10.1055/s-0040-1710541.

May 2nd update – Studies 73 to 75 added

Study 75 – 10 vaginal births in China

Among 88 pregnant women with confirmed or suspected COVID-19 admitted to the obstetric isolation ward of Zhongnan Hospital of Wuhan University between January 20 and March 2, ten delivered vaginally (click here or LIAO ijgo.13188). All 7 tested neonates were negative. Three babies were not tested. These ten cases don’t overlap with those in studies 1, 13 & 56, who had all delivered by Caesarean, but probably overlap with studies 55 and 57. Not added to running totals. Citation: Jing Liao, Xiaoyan He, Qing Gong, Lingyun Yang, Chunhua Zhou, Jiafu Li. Analysis of vaginal delivery outcomes among pregnant women in Wuhan, China during the COVID‐19 pandemic. First published: 29 April 2020 https://doi.org/10.1002/ijgo.13188

Study 74 – Case report from Portugal

A healthy woman with “occasional dry cough” tested positive at term and was delivered by Caesarean (click here or Lyra Portugal case13883-54440-1-PB. The baby was uninfected and both did well. Citation: LYRA, Joana et al. Cesarean Section in a Pregnant Woman with COVID-19: First Case in Portugal. Acta Médica Portuguesa, [S.l.], v. 33, n. 6, p. 429-431, june 2020. ISSN 1646-0758. 

Study 73 – 28 women from China

Among pregnant women cared for in the Central Hospital of Wuhan between 15 January to 15 March 2020. (click here or Quancheng IJID 1-s2.0-S1201971220302800-main) there were 17 Caesareans, 5 vaginal births, 4 medical abortions and 2 ongoing pregnancies. Total 30 [sic]. They include one set of twins. No babies were infected, and no mothers or babies died. The authors admit that these data are included in Study 55. They are probably also included in study 57, & overlap with Study 39.  Not added to running totals. Citation: Qiancheng X, Jian S, Lingling P, Lei H, Xiaogan J, Weihua L, Gang Y, Shirong L, Zhen W, GuoPing X, Lei Z, The sixth batch of Anhui medical team aiding Wuhan for COVID-19, Coronavirus disease 2019 in pregnancy, International Journal of Infectious Diseases (2020), doi: https://doi.org/10.1016/j.ijid.2020.04.065

May 1st update – Study 72 added

Study 72- Miscarriage in Switzerland

A 28-year-old with Covid-19 miscarried at 19 weeks gestation at Lausanne University Hospital (click here or second trimester miss jama_baud_2020_ld_200040 ). Placental swabs were positive for SARS-CoV-2. The mother’s outcome was not reported. Citation: David Baud, Gilbert Greub, Guillaume Favre, Carole Gengler, Katia Jaton, Estelle Dubruc, Léo Pomar. Second-Trimester Miscarriage in a Pregnant Woman With SARS-CoV-2 Infection. JAMA. Published online April 30, 2020. doi:10.1001/jama.2020.7233

30th April update – Studies 68 to 71 added

Study 71 – Follow-up of 4 women from Study 6

Patients 12-15 in Study 6 from Tongji hospital, Wuhan, China, were still in hospital at the time of the report. This (click here or YANG L_Tongji_AJR) describes follow-up till March 30th. All four had been discharged and were still pregnant. Citation: Lin LiDehan Liu, Lian Yang. Follow-Up Information About the Four Pregnant Patients With Coronavirus Disease (COVID-19) Pneumonia Who Were Still in the Hospital at the End of Our Study American Journal of Roentgenology: W1-W2. 10.2214/AJR.20.23247

Study 70 – Maternal death from Iran

A 22-year-old developed Covid-19 at 32 (or possibly 30) weeks gestation, and was treated at Imam Khomeini Hospital of Mazandaran University, Sari (click here or ZAMANIYAN M_Iran_Prenatal diagnosis). She was delivered by Caesarean section, but on day 10 required ventilation, and died on day 15. The first baby swabs were negative, but amniotic fluid and later baby swabs were positive. Apart from developing a fever the baby did well. The clinical details suggest that she was not included in Study 67. Citation: Marzieh Zamaniyan, Aghdas Ebadi, Samaneh Aghajanpoor Mir, Zahra Rahmani, Mohammadreza Haghshenas, Setareh Azizi. Preterm delivery in pregnant woman with critical COVID‐19 pneumonia and vertical transmission. Prenatal diagnosis. First published:17 April 2020 https://doi.org/10.1002/pd.5713

Study 69 – Case report from USA

A patient with Covid-19 at 33 weeks gestation required intubation and ventilation for 11 days (click here or Kelly false negative SARSCOV2 AJOGMFM). The baby was delivered by Caesarean. The mother has been extubated, and is recovering. The baby tested negative and is well. From author affiliations the patient was probably cared for in Barnes Jewish Hospital in St Louis, Missouri. Citation: Jeannie C Kelly, Michael Dombrowksi, Micaela O’neil-Callahan, Annessa S Kernberg, Antonina I Frolova, Molly J Stout.  False-Negative COVID-19 Testing: Considerations in Obstetrical Care. American Journal of Obstetrics & Gynecology MFM Available online 28 April 2020, https://doi.org/10.1016/j.ajogmf.2020.100130

Study 68 – 55 pregnant women in the UK ISARIC report

This preprint from the  International Severe Acute Respiratory and emerging Infections Consortium (ISARIC) (click here or ISARIC UK 2020.04.23.20076042v1.full) includes 16,749 hospitalised UK patients with COVID-19. This represents 14.7% of people who have tested positive for COVID-19 in the UK, most of whom have not required hospital admission, and 28% of admissions with COVID-19. 55/963 (6%) of the women of reproductive age were pregnant. This is similar to the estimated proportion of pregnant women in the community. Pregnancy was not associated with mortality. Citation: Annemarie B Docherty, Ewen M Harrison, Christopher A Green, Hayley E Hardwick, Riinu Pius, Lisa Norman, Karl A Holden, Jonathan M Read, Frank Dondelinger, Gail Carson, Laura Merson, James Lee, Daniel Plotkin, Louise Sigfrid, Sophie Halpin, Clare Jackson, Carrol Gamble, Peter W Horby, Jonathan S Nguyen-Van-Tam, Jake Dunning, Peter JM Openshaw, J Kenneth Baillie, Malcolm Gracie Semple. Features of 16,749 hospitalised UK patients with COVID-19 using the ISARIC WHO Clinical Characterisation Protocol. medRxiv 2020.04.23.20076042; doi: https://doi.org/10.1101/2020.04.23.20076042

29th April update.

Study 67 – 7/9 maternal deaths with severe disease in Iran

This preprint from Am J Obstet Gynecol (click here or Aagaard_W20-2021) reports 9 pregnant women with severe Covid-19 treated between mid-February & mid-March 2020. The hospitals, exact ages and exact dates of admission and death were concealed to protect anonymity. Seven mothers died, one recovered and one remains seriously ill.  Of the babies, 6 died (incl one set of twins) and 5 survived (incl one set of twins). These cases may overlap with those in studies 23 & 43. Citation: Sedigheh Hantoushzadeh, Alireza A. Shamshirsaz, Ashraf Aleyasin, Maxim D. Seferovic, Soudabeh Kazemi Aski, Sara E. Arian, Parichehr Pooransari, Fahimeh Ghotbizadeh, Soroush Aalipour, Zahra Soleimani, Mahsa Naemi, Behnaz Molaei, Roghaye Ahangari, Mohammadreza Salehi, Atousa Dabiri Oskoei, Parisa Pirozan, Roya Faraji Darkhaneh, Mahboobeh Gharib Laki, Ali Karimi Farani, Shahla Atrak, Mir Mohammad Miri, Mehran Kouchek, Seyedpouzhia Shojaei, Fahimeh Hadavand, Fatemeh Keikha, Maryam Sadat Hosseini, Sedigheh Borna, Shideh Ariana, Mamak Shariat, Alireza Fatemi, Behnaz Nouri, Seyed Mojtaba Nekooghadam, Kjersti Aagaard. Maternal death due to COVID-19, American Journal of Obstetrics and Gynecology, Volume 223, Issue 1, 2020, Pages 109.e1-109.e16, ISSN 0002-9378, https://doi.org/10.1016/j.ajog.2020.04.030.
(http://www.sciencedirect.com/science/article/pii/S0002937820305160)

28 April update – Studies 64-66 added

Study 66 – 9 maternal deaths due to Covid-19

Nine maternal deaths (click here or Maternal deaths AJOG L20-082. Two from Iran had been reported in Study 23 below. Of the five from Brazil, two post-partum deaths in women delivered by Caesarean section, are referenced to the Brazilian Ministry of Health. No further details are given. The other three are sourced to Brazilian newspapers. The first link provided (click here) goes to the newspaper Folha de Londrina, but not to the report of the maternal death. The 2nd link (click here) describes the death of Viviane Albuquerque, age 33 from Pernambuco, at 32 weeks gestation (added here). The third link (click here) is broken. The final two deaths occurred in Mexico. The first is attributed to the Mexican Ministry of Health. The second to a newspaper report. The link provided (click here) goes to a report of two maternal deaths from Covid-19. Added to the news reports here.  Not added to the running totals. Citation:  Amorim MMR, Soligo Takemoto ML, Fonseca EBD. Maternal deaths with coronavirus disease 2019: a different outcome from low- to middle-resource countries? Am J Obstet Gynecol. 2020;223(2):298-299. doi:10.1016/j.ajog.2020.04.023

Study 65 – 5 patients with severe disease from USA

Five women in Philadelphia, who required ventilation (click here or Hirshberg AJOG L20-083). Three were delivered by Caesarean, and two remain undelivered. No mothers or babies died, but one woman remains severely ill. Citation: Hirshberg A, Kern-Goldberger AR, Levine LD, Pierce-Williams R, Short WR, Parry S, Berghella V, Triebwasser JE, Srinivas SK. Care of critically ill pregnant patients with coronavirus disease 2019: a case series. Am J Obstet Gynecol. 2020 Aug;223(2):286-290. doi: 10.1016/j.ajog.2020.04.029. Epub 2020 May 1. PMID: 32371056; PMCID: PMC7252050.

Study 64 – 42 cases from Lombardy, Italy

This pre-print in BJOG (click here or 1471-0528.16278) describes the 42 cases in study 32 in much more detail. They were cared for in 6 hub hospitals: Milan-Mangiagalli and Sacco, Bergamo Pope Giovanni XXIII; Brescia-Civil Hospital; Monza-S. Gerardo Hospital/MBBM Foundation; Pavia-San Matteo, and 6 spoke hospital Milan-Melloni and S. Giuseppe; Seriate-Bolognini; Treviglio-Civil
Hospital, The Maternity Hospital of Padua and the Maternity Hospital of Modena. Citation: Enrico Ferrazzi, Luigi Frigerio, Valeria Savasi, Patrizia Vergani, Federico Prefumo, Santa Barresi, Stefano Bianchi, Elena Ciriello, Fabio Facchinetti, Maria Teresa Gervasi, Enrico Iurlaro, Alessandra Kustermann, Giovanna Mangili, Fabio Mosca, Luisa Patanè, Donata Spazzini, Arsenio Spinillo, Giuseppe Trojano, Michele Vignali, Antonella Villa, GianVincenzo Zuccott,i Fabio Parazzini, Irene Cetin. Vaginal delivery in SARS‐CoV‐2 infected pregnant women in Northern Italy: a retrospective analysis. BJOG 27 April 2020 https://doi.org/10.1111/1471-0528.16278 [important]

27 April update – Studies 58-63 added

Study 63. ICNARC 24 April update

The 24 April update (click here or ICNARC COVID-19 report 2020-04-24) contains 20 currently, and 25 recently, pregnant women critically ill with Covid-19. Of these 5 and 7 respectively had received advanced respiratory support. Excluded from running totals.

Study 62. Case report from China

A 22 year old woman with asymptomatic COVID-19 was delivered by Caesarean on Feb 11, 2020 at the No 2 People’s Hospital of Hefei City (click here). The baby tested negative and both did well. Although this hospital does not appear on www.grid.ac this is the first report from Hefei City, which is 373 km from Wuhan. Citation: Lu D, Sang L, Du S, Li T, Chang Y, Yang XA. Asymptomatic COVID-19 infection in late pregnancy indicated no vertical transmission. J Med Virol. 2020 Apr 24. doi: 10.1002/jmv.25927. [Epub ahead of print]

Study 61. 32 Covid-19 screen positive women from USA

Out of 161 pregnant women admitted in labour to New York University Winthrop Hospital between March 30 & April 12, and screened for Covid-19, 32 were positive, of whom 11 were symptomatic (click here or AJOG_Screening_all_pregnant_women vintzileos). Of 29 neonates tested all were negative with three results pending. No clinical outcomes reported. Citation: William S VINTZILEOS, Jolene MUSCAT, Eva HOFFMANN, Duc VO, Nicole S JOHN, Rosanne VERTICHIO, Anthony M VINTZILEOS, Screening all pregnant women admitted to Labor and Delivery for the virus responsible for 2 COVID-19 American Journal of Obstetrics & Gynecology. in press. 

Study 60. Preterm labour in a patient with Covid-19

A woman from South Carolina, USA, developed Covid-19 at 23 weeks, was treated for suspected preterm labour at 24 weeks, and recovered. The pregnancy is ongoing at 27 weeks (click here or Browne Aj Peri preterm labour). Citation: Paul C. Browne, Jennifer B. Linfert, Emilio Perez-Jorge. Successful Treatment of Preterm Labor in Association with Acute COVID-19 Infection. Am J Perinatol. Published Online 24 April 2020. DOI: 10.1055/s-0040-1709993

Study 59. Two patients with Covid-19 & negative amniocentesis, China

Two women from Tongji Hospital, Wuhan developed Covid-19 in the first trimester and underwent amniocentesis in the second (click here or Yu SARS COV2 in AF Lancet Infect Dis 20). Both specimens were negative. Both cases may overlap with those in Studies 55 and 57. Not added to running totals. Citation: Nan Yu, Wei Li, Qingling Kang, Wanjiang Zeng, Ling Feng, Jianli Wu. No SARS-CoV-2 detected in amniotic fluid in mid-pregnancy. Lancet Infect Dis 2020 Published Online April 22, 2020 https://doi.org/10.1016/S1473-3099(20)30320-0

Study 58. First case report from India

An asymptomatic woman at 38+6 weeks gestation tested positive for COVID-19 (click here or Sharma India ijgo.13179). She delivered by Caesarean section, and her breast-fed baby tested negative on day 7. Both recovered. Citation: K. Aparna Sharma, Rajesh Kumari, Garima Kachhawa, Anjolie Chhabra, Ramesh Agarwal, Akash Sharma, Neerja Bhatla. Management of the first patient with confirmed COVID‐19 in pregnancy in India: From guidelines to frontlines. Int J Gynecol Obstet. In press. doi:10.1002/ijgo.13179 

25 April update – Studies 56 & 57 added.

Study 57. 116 cases from 25 hospitals in China

This preprint from Am J Obstet Gynecol (click here) includes 116 mothers with Covid-19 (65 lab confirmed, 51 clinically diagnosed), of whom 8 had severe disease. None died. 99 mothers had delivered 100 babies (one set of twins) of whom one died. This paper claims to be an “an expanded series that have included 33 published cases.16,18-20”. Their reference 16 is our Study 1, ref 18 is our Study 38 and ref 19 is our Study 6a.  Their reference 20 is as follows:  “Lei D, Wang C, Li C, et al. Clinical characteristics of COVID-19 in pregnancy: analysis of nine cases. Chin J Perinat Med 2020,23:doi: 10.3760/cma.j.cn113903-20200216-00117.” Although cited in a number of reviews we have so far been unable to find the original source. Update 18 December – see Study 511

The patients were collected from 25 hospitals within and outside Hubei province, between January 20 and March 24, 2020. Three recruiting hospitals, all from Wuhan, listed in the supplementary material, overlap with those in study 55 (appendix table s1). These are Zhongnan Hospital of Wuhan univerisity, the Central Hospital of Wuhan, and Tongi Hospital, all multiple reporters of Covid-19 in pregnancy. Thus it is likely that, in addition to the studies cited, this series overlaps considerably with Study 55. Not added to running totals. The patient requiring ECMO came from Zhongshan, Guangdong. She is probably the same woman reported as treated with ECMO from the city in Study 3. She survived. Citation: Yan J, Guo J, Fan C, Juan J, Yu X, Li J, Feng L, Li C, Chen H, Qiao Y, Lei D, Wang C, Xiong G, Xiao F, He W, Pang Q, Hu X, Wang S, Chen D, Zhang Y, Poon LC, Yang H, Coronavirus disease 2019 (COVID-19) in pregnant women: A report based on 116 cases, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.04.014.

Study 56. Seven mothers and babies from Zhongnan Hospital

All mothers had Covid-19 and were delivered by Caesarean. No mothers or babies died (click here). 6/7 babies had a range of swabs taken, all of which were negative. Due to probability of duplication with Studies 1 and 55, not included in running totals. Citation. Pu Yang, Xia Wang, Pin Liu, Cong Wei, Bingyan He, Junwen Zheng, Dongchi Zhao. Clinical characteristics and risk assessment of newborns born to mothers with COVID-19 Journal of Clinical Virology Volume 127, June 2020, 104356.  https://doi.org/10.1016/j.jcv.2020.104356&nbsp;

22 April update – studies 53-55 added.

Study 55. 118 cases with Covid-19 from Wuhan collected by the National Health Commission of China

This regional series, published in New Engl J Med, of women treated between December 8, 2019, & March 20, 2020, was extracted by the National Health Commission of China, which stores the medical records of all 50 designated hospitals in Wuhan city (click here). Nineteen of the 50 hospitals had reported cases (Appendix table S1, click here). No mothers died, and apart from 3 spontaneous abortions, 2 ectopic pregnancies, & 4 induced abortions, no babies died. At the next running total update we will replace all other cases from hospitals in Wuhan with these data. Citation: Lian Chen, Qin Li, Danni Zheng, Hai Jiang, Yuan Wei, Li Zou, Ling Feng, Guoping Xiong, Guoqiang Sun, Haibo Wang, Yangyu Zhao, Jie Qiao, Clinical Characteristics of Pregnant Women with Covid-19 in Wuhan, China. New Engl J Med. April 17, 2020 DOI: 10.1056/NEJMc2009226 [important]

Study 54. Six confirmed, & two suspected cases from China

The eight patients from the Maternal and Child Health Hospital of Hubei Province, Wuhan, between January 23 and February 10, 2020 (click here) probably overlap with other reports from the same hospital. They are not included in the running totals. Citation: Wu, C., Yang, W., Wu, X. et al. Clinical Manifestation and Laboratory Characteristics of SARS-CoV-2 Infection in Pregnant Women. Virol. Sin. (2020). https://doi.org/10.1007/s12250-020-00227-0

Study 53. Case report from Las Palmas de Gran Canaria, Spain

A 44-year-old woman developed Covid-19 at 29+2 weeks gestation (click here or 1-s2.0-S0014256520301120-main (002)). She was treated at Hospitalario Universitario Insular Materno Infantil, and required mechanical ventilation and delivery by caesarean. Both mother and baby recovered. [Spanish. Google translate] Citation: González Romero D, Ocampo Pérez J, González Bautista L, Santana-Cabrera L. Pronóstico perinatal y de la paciente embarazada con infección por COVID-19. Revista Clínica Española Available online 17 April 2020, https://doi.org/10.1016/j.rce.2020.04.006

20 April update Studies 48 – 52 added

Study 52. ICNARC update 17 April

This update of the UK Intensive Care National Audit & Research Centre (ICNARC) database (click here or ICNARC COVID-19 report 2020-04-17.pdf (1) mentions 16 currently, and 21 recently, pregnant women with Covid-19 who are or had been critically ill. Three & six respectively had received advanced respiratory support. Excluded from running totals.

Study 51. Case report from the British American Hospital, Lima, Peru

A 41 year old women with severe Covid-19 requiring ventilation was delivered by caesarean section at 33 weeks gestation (click here or Alzamora Am J Perintal Apr 18 . The baby was isolated but a nasopharyngeal swab taken at 16 hours was positive for SARS-COV-2. The baby was ventilated for 12 hours, and later, at age 6 days, developed mild respiratory symptoms. The mother’s serology is reported on day 4, but otherwise the maternal outcome is not reported. It is presumed that she recovered. Citation: Maria Claudia Alzamora, Tania Paredes, David Caceres, Camille M. Webb, Luis M. Valdez, Mauricio La Rosa. Severe COVID-19 during Pregnancy and Possible Vertical Transmission. Am J Perinatal. Online April 18. DOI https://doi.org/10.1055/s-0040-1710050.&nbsp;

Study 50. A severe case of Covid-19 from USA

A 39 year old woman presented at 31 weeks gestation with severe Covid-19. She required ventilation. After 8 days on ITU she was delivered by Caesarean section for fetal bradycardia at the Good Samaritan Hospital. Cincinnati, Ohio. The baby was intubated on NICU for three days, and isolated for 14. Amniotic fluid and nasopharyngeal swabs were negative. The mother remains on synchronized intermittent mandatory ventilation. The clinical details and patient age indicate that this is not patient no. 42 (click here) reported in the Ohio newspapers. Citation: Schnettler WT, Al Ahwel Y, Suhag A, Severe ARDS in COVID-19-infected pregnancy: obstetric and intensive care considerations American Journal of Obstetrics & Gynecology MFM (2020), doi: https://doi.org/10.1016/j.ajogmf.2020.100120.

Study 49. 62 pregnant women from USA

Over four weeks to March 29th, 62 out of 3064 pregnant women attending an unnamed 14 hospital group tested positive for SARS-COV2 (click here).  No further details given, & since they may overlap with other NY cases, not included in running totals. Citiation: Tekbali A, Grünebaum A, Saraya A, McCullough L, Bornstein E, Chervenak FA. Pregnant versus non-pregnant SARS-CoV-2 and COVID-19 Hospital Admissions: The first 4 weeks in New York, American Journal of Obstetrics and Gynecology (2020), doi: https://doi.org/10.1016/j.ajog.2020.04.012.

Study 48. One case from Canada & one from France.

Two cases (click here or COVID coagulopathy Canada jth.14856)  One delivered in Mount Sinai Hospital, Toronto, and one in Antoine Béclère hospital in Clamart. Citation: Evangelia Vlachodimitropoulou Koumoutsea, Alexandre J. Vivanti, Nadine Shehata, Alexandra Benachi, Agnes Le Gouez, Celine Desconclois, Wendy Whittle, John Snelgrove, Kinga Ann Malinowski. COVID19 and acute coagulopathy in pregnancy. J Thrombosis Haemostasis. 17 April 2020. https://doi.org/10.1111/jth.14856

19 April update Study 47 added.

Study 47. 13 pregnant women in ITU from France

Thirteen pregnant women have been admitted to intensive care in France (click here or COVID19_PE_20200418 Report in French). None have died. Not included in running totals. Citation: COVID-19: epidemiological update of April 16, 2020 Santé Publique France.

18 April update. Study 46 (16 April update of NethOSS) added, & study 42 (prev NethOSS data) removed from running totals

Study 46. 107 women from the Netherlands Covid-19 registry

This 16 April update of NethOSS (click here), accessed 18 April 2020, contains the following. 5/91 women with brief additional details were admitted to intensive care. 25 have given birth, eight by Caesarean. No mother or baby has died. Citation: See Study 42. Available here. Accessed 18 April. 

16 April update. Studies 44 & 45 added. HT @Belinda_J_Lowe for study 45. We’ve also done some housekeeping today. Study 13 probably overlaps with study 1, so S13 has been removed from running totals. Study 3 includes 13 patients from multiple centres, both in and outside Hubei province, who may overlap with other studies. 12 mothers (3 undelivered) and 9 babies therefore removed from the running total. Only S3, case 6, woman on ECMO & baby stillborn & preterm, does not appear to have been reported elsewhere, so remains in the running totals.

Study 45. Case report from Australia

Mother age 31, with mild Covid-19 confirmed by testing at 40w+0d (click here or full text preprint here). Spontaneous labour at 40w+3d. Ventouse birth. Baby breast fed. Covid-91 neg swab at 24 hours. Mother and baby well. This case report from Bond University Hospital, Southport, Queensland, is the first from this country. Citation: Lowe B, Bopp B. COVID‐19 vaginal delivery – a case report. ANZOG 15 April 2020. https://doi.org/10.1111/ajo.13173

Study 44.  42 suspected & 13 confirmed cases from China

Thirteen pregnant women all seen at Tongji Hospital grid.412793.a between Jan 20 & Mar 5, 2020 (click here). Four delivered vaginally and nine by Caesarean. All mothers had mild disease and none died. The baby details for the Covid and non-Covid mothers are reported together. These cases probably overlap with previous reports from Tongji hospital so not included in running totals. Citation: Hui yang, Guoqiang Sun, Fei Tang, Min Peng, Ying Gao, Jing Peng, Hui Xie, Yun Zhao, Zhichun Jin, Clinical Features and Outcomes of Pregnant Women Suspected of Coronavirus Disease 2019, Journal of Infection (2020), doi: https://doi.org/10.1016/j.jinf.2020.04.003&nbsp;

14 April update Studies 41 – 43 added.

Study 43. A maternal death from Covid-19 in Iran

25 June update. This paper has been withdrawn because the case, as we had suspected, had also been included in Study 67. Study 67 had been submitted first, albeit to another journal, so the authors judged that it had priority. Details on Retraction Watch (click here)

A 27 year old woman was transferred to Vali-e-asr Hospital at 30 weeks gestation (click here or Karami Travel med Apr 11 2020) with severe respiratory failure. She required intubation and ventilation. A few hours later she delivered a stillborn baby vaginally, and a few hours after that she died. Post-mortem on the mother confirmed SARS-Cov-2 in the lungs. No further details are given about the baby.  Vali-e-asr Hospital does not appear on Grid.ac but is part of Zanjan University of Medical Sciences. grid.469309.1. This is the first academic report (as opposed to unconfirmed news reports) of a maternal death due to Covid-19.  Citation: Parisa Karami, Maliheh Naghavib, Abdolamir Feyzib, Mehdi Aghamohammadic, Mohammad Sadegh Novinc, Ahmadreza Mobaiend, Mohamad Qorbanisania, Aida Karamia, Amir Hossein Norooznezhad. Mortality of a pregnant patient diagnosed with COVID-19: A case report with clinical, radiological, and histopathological findings. Travel Medicine and Infectious Disease, in press. https://doi.org/10.1016/j.tmaid.2020.101665

Study 42. 89 women from the Netherlands Covid-19 registry

This is the first Covid-19 in pregnancy registry report of which we are aware. It has not been formally published, but is available here and regularly updated.  Using Google translate, the 9 April version, accessed 14 April 2020 contains the following. 5/89 pregnant women with Covid-19 have been admitted to intensive care. 19 women have given birth, four by Caesarean. No mother or baby has died. Updated by study 46 & removed from running totals. Citation: The Nederlandse Vereniging voor Obstetrie en Gynaecologie (Dutch Association for Obstetrics and Gynecology) (NVOG). Registratie COVID-19 positieve zwangeren in NethOSS (Update registration COVID-19 positive pregnant women in NethOSS). Available https://www.nvog.nl/actueel/registratie-van-covid-19-positieve-zwangeren-in-nethoss/ Accessed 14 April. [important]

Study 41. 33 women from USA

These 33 women with Covid-19 delivered infants at the New York–Presbyterian Allen Hospital and Columbia University Irving Medical Center between March 22 & April 4, 2020 (click here). They presumably include the 18 women with Covid-19 previously reported as having delivered in the same two hospitals (Studies 14 & 27), as well as some of the women who were at the time undelivered in those two series. Since no birth details are given, these cases have not been included in running totals. Citation: Sutton, D, Fuchs, K, D’Alton M, Goffman D. Universal Screening for SARS-CoV-2 in Women Admitted for Delivery. New Engl J Med April 13, 2020. DOI: 10.1056/NEJMc2009316

13 April update Studies 39 and 40 added.

Study 40. 17 pregnant women from China

These 17 women with Covid-19, all delivered by Caesarean section in Remnin hospital (click here or Khan Clin Micro Infect 27 Mar), almost certainly are the same women as in studies 6a & 12. They have not been added to the running totals. Citation: Khan S, Jun L, Nawsherwan Siddique R, Li Y, Han G, Xue M, Nabi G, Liu J, Association of COVID-19 infection with pregnancy outcomes in healthcare workers and general women, Clinical Microbiology and Infection, https://doi.org/10.1016/j.cmi.2020.03.034&nbsp;

Study 39. 23 pregnant women from China

23 pregnant women with COVID-19 from the Central Hospital of Wuhan. Wu ijgo.13165 Three patients terminated the pregnancy in the first trimester. Of the other 20, 18 delivered by Caesarean and two vaginally. There was one set of twins. No neonates were infected. This is the first report from this hospital which has a unique GRID reference. We have therefore added these to the running totals. Citation: Xiaoqing Wu, Ruihong Sun, Jianpu Chen, Yuanliang Xie, Shutong Zhang, Xiang Wang. Radiological findings and clinical characteristics of pregnant women with COVID-19 pneumonia In J Gynecol Obstet. In press doi: 10.1002/ijgo.13165 

11 April update Studies 34 – 38 added.

Study 38. 41 women from China

Out of 41 pregnant women from the Maternal and Child Health Hospital of Hubei Province, with typical Covid-19 infection on lung CT, 16 were SARS-CoV-2 positive, 17 negative and 8 not tested. Nineteen were inpatients for delivery, and the rest outpatients from 22 weeks onwards. No birth details were given and in view of the probability of overlap with other cases in the same hospital none have been added to the running totals. Citation: H. Liu, F. Liu and J. Li et al., Clinical and CT imaging features of the COVID-19 pneumonia: Focus on pregnant women and children, Journal of Infection, https://doi.org/10.1016/j.jinf.2020.03.007

Study 37. Three vaginal births in China

Three babies were born vaginally to women with Covid-19, one preterm, two term. None were infected. Khan 3 vaginal births renmin. All previous reports from Renmin (Studies 6a, 10, 12 & 36) were of Caesarean births, so these have been included as non-duplicates in the summary totals. Citation: Suliman Khan, Liangyu Peng, Rabeea Siddique, Ghulam Nabi, Nawsherwan, Mengzhou Xue, Jianbo Liu, Guang Han. Infection Control & Hospital Epidemiology as part of the Cambridge Coronavirus Collection. March 2020. DOI: 10.1017/ice.2020.84

Study 36. Caesarean birth in 17 women in China

This case series includes details of the Caesarean births of 17 women with Covid-18 in Renmin Hospital of Wuhan University Chen 17 renmin cs. All mothers and babies survived. However the series probably includes the 16 cases also reported from Remnin in Chinese (study 6a), which included the same number, three, preterm patients, all also delivered by Caesarean. They may also overlap with study 10; both studies mention two doctors delivered by Caesarean in Renmin. The obstetrican on study 36, Bi-heng Cheng, is shared with study 6a. We have therefore not included these cases in the running total. Citation: Rong Chen, Yuan Zhang, Lei Huang, Bi-heng Cheng, Zhong-yuan Xia, Qing-tao Meng, Safety and efficacy of different anesthetic regimens for parturients with COVID-19 undergoing Cesarean delivery: a case series of 17 patients. Can J Anesth https://doi.org/10.1007/s12630-020-01630-7

Study 35. Four neonates with Covid-19 from China

Four infected neonates (age less than 1 month) all born by Caesarean section (click here). They were identified by searching the national database of 81,026 laboratory-confirmed cases up to March 13 using the same methods as in a study of infants age 1 month to one year reported in JAMA (click here but not listed in this blog post). It seems likely that they overlap with the three infected neonates reported earlier in JAMA (study 12), the case report in Clinical Infectious Diseases (study 11) or the infected neonate reported in Lancet Inf Dis (study 15). We have therefore not included them in the running totals. Citation: Zhi-Jiang Zhang, Xue-Jie Yu, Tao Fu, Yu Liu, Yan Jiang, Bing Xiang Yang, Yongyi Bi. Novel Coronavirus Infection in Newborn Babies Under 28 Days in China. European Respiratory Journal 2020; DOI: 10.1183/13993003.00697-2020

Study 34. Case report of uninfected baby from China

Abstract (click here). Full text (here). A 25 year old woman with Covid-19 at 35 weeks recovered and had a normal vaginal birth of a 3070g boy at 38w + 4d. The baby had no signs of past or present infection with SARS-COV-2. The birth occurred at YouAn Hospital, Capital Medical University, Beijing, which has not previously reported cases in pregnancy, but the mother had been transferred from an unnamed hospital in Wuhan. Nevertheless we have included this as a non-duplicated case in summary totals. Citation: Xiali Xiong, Hong Wei, Zhihong Zhang, Jing Chang, Xiaopeng Ma, Xiang Gao, Qiang Chen, Qiumei Pang. Vaginal Delivery Report of a Healthy Neonate Born to a Convalescent Mother with COVID-19 J Med Virol. 2020 Apr 10. doi: 10.1002/jmv.25857. 

10th April update Study 33 added

Study 33. US Centres for Disease Control reports 143 pregnant women

Preliminary data on lab-confirmed COVID-19 reported to CDC Feb 12–March 28, 2020. Of 7,162 cases, 143 were pregnant. Of these 72 stayed home, 31 hospitalised (non ICU), 4 entered ICU, and  36 had unknown hospitalisation status. “[…] for […] pregnancy, few severe outcomes were reported […].” Many probably reported elsewhere, so not added to running totals. Citation: Preliminary Estimates of the Prevalence of Selected Underlying Health Conditions Among Patients with Coronavirus Disease 2019 — United States, February 12–March 28, 2020. MMWR Morb Mortal Wkly Rep 2020;69:382–386. DOI: http://dx.doi.org/10.15585/mmwr.mm6913e2external icon. [important]

9 April update. Study 31 & 32 added. Keelin O’Donoghue & Kate Walker have joined the team. Thank you also to Nicola Vousden for alerting us to 31.

Study 32. 42 women from Italy

This pre-print Ferrazzi Lombardy ijgo.13162 cites a paper in press describing 42 pregnant women from Lombardy, Italy who had Covid-19 and delivered, 18 by Caesarean, and 24 vaginally. Two were spontaneously preterm. Seven women required CPAP or were admitted to ICU, but all “eventually did well”. No baby details are given. This is the first scientific report from Italy. Citation: Ferrazzi EM, Frigerio L, Cetin I, Vergani P, Spinillo A, Prefumo F, Pellegrini E, Gargantini G.COVID-19 Obstetrics Task Force, Lombardy, Italy: executive management summary and short report of outcome. Int J Gynecol Obstet in press. [important]

Study 31. Case report from Turkey

Report from Dept OBGYN, Ankara University, Faculty of Medicine. Woman age 32, with Covid-19 at 35 weeks gestation, delivered by Caesarean section prior to admission to intensive care (click here). Birthweight 2790g. Three days after birth mother required intubation and ventilation, and she remains in intensive care. Baby not infected.  Citation: E. Kalafat E. Yaprak G. Cinar B. Varli S. Ozisik C. Uzun A. Azap A. Koc Lung ultrasound and computed tomographic findings in pregnant woman with COVID‐19 Ultrasound Obstet Gynecol. First published: 06 April 2020 https://doi.org/10.1002/uog.22034

8 April update. Study 30 added. Thank you to Nicola Vousden (click here) for alerting me to this one. From tomorrow, www.ripe-tomato.org will raise its Covid-19 in pregnancy game. Two colleagues, Keelin O’Donoghue from Cork and Kate Walker from Nottingham, will join in searching and classifying, we will improve and publish our search strategy, and register this project on PROSPERO. Stand by for details.

Study 30. 16 women with Covid-19 pneumonia from Hubei province, China

Sixteen pregnant women with confirmed COVID-19 pneumonia, and 18 with pneumonia on chest imaging who tested negative, were compared with two groups of control pregnancies (click here or ciaa352). The comparative design is similar to study 6a which, apart from an English abstract, has only been published in Chinese. However the hospital and authors differ, so I’m confident there is no overlap. Citation: Li N, Han L, Peng M, Lv Y, Ouyang Y, Liu K, Yue L, Li Q, Sun G, Chen L, Yang L. Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study. Clin Infect Dis. 2020 Mar 30. pii: ciaa352. doi: 10.1093/cid/ciaa352. [Epub ahead of print]

7 April update Studies 27-29 added. HT Keelin O’Donogue @Keelinodonoghue & Penny Wilson @nomadicgp

Study 29. ICNARC report 4 April 2020

This report ICNARC COVID-19 report 2020-04-04.pdf  or click here, from the UK Intensive Care National Audit & Research Centre (ICNARC) mentions two currently, and six recently (<6 weeks) pregnant women with Covid-19 who were also critically ill. One of the currently pregnant, and two of the recently pregnant women, were receiving advanced respiratory support. Excluded from running totals.

Study 28. Seven cases from New Jersey USA

Pre-print from Am J Obstet Gynecol MFM 1-s2.0-S2589933320300434-main, or click here, of two pregnant women with Covid-19 who developed cardiomyopathy. Report also mentions five other pregnant women with Covid-19 in Newark Beth Israel Medical Center.  Details are only given for the two women with cardiomyopathy, and no baby details are given. For consistency of numbers I’ve assumed the other five pregnancies are ongoing in running totals. Citation: Alexander Juusela, Munir Nazir Martin Gimovsky. Two Cases of COVID-19 Related Cardiomyopathy in Pregnancy. AJOG MFM Available online 3 April 2020, doi.org/10.1016/j.ajogmf.2020.100113

Study 27. Expanded series from NY Presbyterian, USA

This pre-print reports 43 pregnant women with COVID-19. It includes 36 new cases, identified during a period of universal testing, and 7 previously reported (Study 14) 43_COVID_040320. Click here. Citation: Breslin N, Baptiste C, Gyamfi-Bannerman C, et al. Coronavirus disease 2019 infection among asymptomatic and symptomatic pregnant women: two weeks of confirmed presentations to an affiliated pair of New York City hospitals. Am J Obstet Gynecol MFM. 2020;2(2):100118. doi:10.1016/j.ajogmf.2020.100118

6 April update. No new scientific reports today. But obstetricians & midwives will enjoy reading the first newspaper report of a Covid-19 pregnancy and birth in France. Case 10 here. Better written and more detailed than many scientific reports.

5 April update. Study 26 added. The first report of puerperal Covid-19. Not added to running totals.

Study 26. The first case report of puerperal COVID-19, China

This baby developed COVID-19 symptoms at age 10 days and was admitted to Wuhan Children’s Hospital age 17 days on February 5, 2020.  Click here for the article in Chinese. What follows is based on Google translate. Both parents are reported to have had Covid-19 symptoms from three days before admission, i. e. day 14 after birth. This is therefore not a case of COVID infection in pregnancy or at birth, and therefore excluded from the running totals. However, the mother had puerperal Covid-19 and is, I believe, the first such case reported. The baby recovered and by implication, albeit not stated explicitly, so did the parents. The first author Zeng Lingkong shares a name with the first author of the series of 33 neonatal cases reported in JAMA Paediatrics, Study 8., but this is clearly not one of the three infected babies reported in that paper. Citation: Zeng Lingkong, Tao Xuwei, Yuan Wenhao, et al. The first neonatal coronavirus pneumonia in China [J]. Chinese Journal of Pediatrics, 2020,58 (04): 279-280. DOI: 10.3760 / cma.j.cn112140 -20200212-00081

4 April update Study 25 added belatedly.

Study 25. Report of the WHO-China Joint Mission on Coronavirus Disease 2019, 16-24 February 2020

Click here or who-china-joint-mission-on-covid-19-final-report for full text including annexes. (For Chinese version click here or who-china-joint-mission-on-covid-19-final-report chinese version. Annexe 6, page 32 of English version: “As opposed to Influenza A(H1N1)pdm09, pregnant women do not appear to be at higher risk of severe disease. In an investigation of 147 pregnant women (64 confirmed, 82 suspected and 1 asymptomatic), 8% had severe disease and 1% were critical.” Neither raw numbers, a citation, nor any further details are given. Assuming the percentages are of all 147, this would imply 12 women with severe disease, and one or two who were critical. In view of the high possibility of double counting – cases notified to the WHO team are likely to have also got reported elsewhere – I’ve left these out of the running total. Citation: Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19) 16-24 February 2020. Report submitted 28 February 2020

3 April update Studies 23 & 24 added. Study 23 is judged unreliable for reasons given below, and study 24 included no pregnancies. Neither have been included in the running totals.

Study 24. No SARS-COV-2 in vaginas of non-pregnant women with severe Covid-19

Although not a study of pregnancy, this report of ten women with confirmed severe COVID-19 pneumonia in Tongji Zhongfa Hospital, Wuhan, China (click here or ciaa375) is reassuring for vaginal birth. None were positive for SARS-CoV-2 by RT-PCR assay in vaginal fluid. Citation: Lin Qiu, Xia Liu, Meng Xiao, Jing Xie, Wei Cao, Zhengyin Liu, Abraham Morse, Yuhua Xie, Taisheng Li, Lan Zhu. SARS-CoV-2 is not detectable in the vaginal fluid of women with severe COVID-19 infection. Clinical Infectious Diseases, ciaa375,  https://doi.org/10.1093/cid/ciaa375

Study 23. Three cases from Iran

This review (click here, full text here) from researchers in both Tehran and Shiraz, includes a report of the births of three infants from infected mothers, apparently not previously reported. The authors’ source was this Iranian ministry website (click here). All three babies were uninfected and survived, but two of the three mothers developed acute respiratory distress syndrome (ARDS) after delivery and died; presumably related to their Covid-19 infection. Citation: Mojgan Karimi-Zarchia, Hossein Neamatzadeh, Seyed Alireza Dastgheib, Hajar Abbasi, Seyed Reza Mirjalili, Thena Behforouz, Farzad Ferdosian, Reza Bahrami. Vertical Transmission of Coronavirus Disease 19 (COVID-19) from Infected Pregnant Mothers to Neonates: A Review. Fetal & Paed Pathol. https://doi.org/10.1080/15513815.2020.1747120&nbsp;

Comment by Jim. Although these cases are reported in a scientific journal, the source is a website. The authors do not claim to have treated either the women nor the babies. The women are said to have delivered in Mazandaran and Zanjan provinces. None of the authors give these provinces as their address.  A google translation of the link provided reveals a report of a single case of a woman with COVID-19 who delivered at 36 weeks in Babol. Mother and baby doing well. Again none of the article authors came from Babol. It seems likely that the source of these three cases is the website alone. We have therefore excluded them from our running totals.

2 April update Thank you to Keelin O’Donoghue, Cork, for pointing me to Studies 18 & 19, which I had missed, and to Ganesh Acharya, Editor-in-Chief AOGS, for permission to upload a pre-publication version of Study 20.

Study 22. Case report from Korea

Delivered by Caesarean section at 37 weeks at Daegu Fatimal Hospital, Korea (click here). The baby was not infected. Mother and baby did well. Citation: Dong Hwan Lee, Jihyang Lee, Eunju Kim, Kyeongyoon Woo, Hak Youle Park, Jihyun An.  Emergency cesarean section on severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) confirmed patient. Korean J Anesthesiol. https://doi.org/10.4097/kja.20116    [Epub ahead of print]

Study 21. Case report from Washington DC, USA

The patient had a normal vaginal delivery at 39 weeks at MedStar Washington Hospital Center (click here). Baby not infected. Both fine. Citation: Iqbal SN Rachael Overcash R, Neggin Mokhtari N,. Haleema Saeed H, Gold S, Auguste T, Mirza M-U, Ruiz M-E, Chahine JJ, Waga M, Wortmann G. An Uncomplicated Delivery in a Patient with Covid-19 in the United States New Engl J Med April 1, 2020 DOI: 10.1056/NEJMc2007605

Study 20. Case report of twins from Sweden

Twins born by Caesarean at 36 weeks in Southern General Hospital, Stockholm. Twins, breast milk & maternal vaginal secretions all Covid-19 negative. Pre-publication version here AOGS-20-0296_Proof_hi with permission of the editor, Ganesh Acharya. Published online 6 April (click here). Citation: Gidlof S, Savchenko J, Brune, T, Josefsson H. COVID-19 in pregnancy with comorbidities: More liberal testing strategy is needed.  Acta Obstetricia et Gynecologica Scandinavica 

Study 19. Case report from China

Woman delivered by Caesarean at 30 weeks in the Affiliated Infectious Hospital of Soochow University, Souzhou. Although “no improvement was made on maximal ventilator support for four hours”, later “informed consent was obtained, an emergency cesarean section under combined spinal-epidural anesthesia was performed” and “uneventful perinatal course”.  Baby isolated and not infected. Both survived. Citation: Xiaotong Wang, Zhiqiang Zhou, Jianping Zhang, Fengfeng Zhu, Yongyan Tang, Xinghua Shen. A case of 2019 Novel Coronavirus in a pregnant woman with preterm delivery. Clinical Infectious Diseases, ciaa200, https://doi.org/10.1093/cid/ciaa200

Study 18. Case report from Honduras, Central America

The woman went into preterm labour and delivered vaginally at 32 weeks at Hospital Escuela of Tegucigalpa, Honduras. Baby not infected. Both doing well at time of report. Citation. Zambrano LI, Fuentes-Barahona IC, Bejarano-Torres DA, Bustillo C, Gonzales G, Vallecillo-Chinchilla G, Sanchez-Martínez FE,  Valle-Reconco JA, Sierra M, Bonilla-Aldana DK, Cardona-Ospina JA, Rodríguez-Morales AJ. A pregnant woman with COVID-19 in Central America. Travel Medicine and Infectious Disease. Online 25 March 2020. https://doi.org/10.1016/j.tmaid.2020.101639&nbsp;

1 April update

Study 6a added (details below).

30th March update

Study 17. Five from China

Two Caesarean and three vaginal births delivered in the Maternal and Child Hospital of Hubei Province, Tongji Medical College grid.412793.a (click here). Or siyu chen.  All mothers recovered. All babies well. According to Wikipaedia the MCH of HP is the 10th clinical college/hospital associated with Tongji Medical College. It is distinct from both Union hospital and Tongji hospital. These five births are therefore additional to those in the various Union Hospital reports, and to those in study 15. Citation: Chen S, Liao E, Shao Y. Clinical analysis of pregnant women with 2019 novel coronavirus pneumonia. J Med Virol. 2020 Mar 28. doi: 10.1002/jmv.25789. [Epub ahead of print] 

Study 16. Three non-cases from Shenzhen 2nd People’s Hospital.

Shenzen, a city of 13 million had had 420 confirmed cases of Covid-19, the second highest number outside Hubei, up to March 11th. Despite an annual birth rate in the city of 188,000, the 2nd People’s Hospital saw no COVID-19 infected pregnant women. Instead they report three suspected cases who, after barrier nursing, and in one case surgery for an ectopic pregnancy, were later confirmed negative. Citation: Yu Chen, Zhe Li, Yuan-Yuan Zhang, Wei-Hua Zhao, Zhi-Ying Yu. Maternal health care management during the outbreak of coronavirus disease 2019 (COVID-19) J Med Virol. 2020 Mar 26. doi: 10.1002/jmv.25787. [Epub ahead of print]

29th March – 3rd update

Study 15. Seven cases from China

These seven cases (click here) delivered at Tongji Hospital, Tongji Medical College grid.412793.a, Huazhong University of Science and Technology, Wuhan, between Jan 1 and Feb 8, 2020. All mothers had mild Covid-19 disease and all were delivered around term by Caesarean section. One baby (Patient 1) tested positive for Covid-19 by throat PCR at 36 hours and was transferred to Wuhan Children’s hospital. His mother’s age, gravidity, parity, lack of direct contact with Hunan seafood market and history of hypothyroidism all suggest this is the same mother/infant dyad as in report 11. Note however the reported birthweights differ 3250g v 3205g. No babies had any clinical symptoms and all (including the transferred one) were discharged home well. Wikipedia lists ten different hospitals/clinical colleges affiliated with Tongji Medical College in Wuhan. The 1st clinical college is called Wuhan Union Hospital. The 2nd clinical college is called Wuhan Tongji Hospital. This series is therefore unlikely to overlap with the various case series from Union Hospital Tongji. Citation: Nan Yu, Wei Li, Qingling Kang, Zhi Xiong, Shaoshuai Wang, Xingguang Lin, Yanyan Liu, Juan Xiao, Haiyi Liu, Dongrui Deng, Suhua Chen, Wanjiang Zeng, Ling Feng, Jianli Wu. Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet Infect Dis 2020 Published Online March 24, 2020 https://doi.org/10.1016/S1473-3099(20)30176-6

29th March – 2nd update.

Study 14. Seven pregnant women from New York Presbyterian, USA

AJOG MFM Preprint (click here) or COVID_Early_Lessons_032620 NY presbyterian. via @neel_shah. The first reported cases outside China. Citation; Breslin N, Baptiste C, Miller R, Fuchs K, Goffman D, Gyamfi-Bannerman C, D’Alton M. COVID-19 in pregnancy: early lessons. Am J Obstet Gynecol. Available online 27 March 2020. https://doi.org/10.1016/j.ajogmf.2020.100111

29th March update. Four more primary reports including ten more cases. All previously unreported.

Study 13. Cord blood serology from six babies in China

Six cases reported in JAMA (click here). All births by Caesarean in Zhongnan Hospital, Wuhan. All mothers mild disease. All babies asymptomatic. Since they were born in a different hospital these are probably additional to the other 33 Wuhan neonates reported in JAMA. Revision 16 April: These are from the same hospital as study 1 and may overlap. Therefore removed from running totals.  Citation: Hui Zeng, Chen Xu, Junli Fan, Yueting Tang, Qiaoling Deng, Wei Zhang, Xinghua Long. Antibodies in Infants Born to Mothers With COVID-19 Pneumonia. JAMA. Published online March 26, 2020. doi:10.1001/jama.2020.4861

Study 12. Case report from China

Case report in JAMA of baby, born at Renmin Hospital, Wuhan, by Caesarean, 23 days after mother developed Covid-19, had IgM antibodies detected in cord blood (click here). This is additional to the two Remnin cases below, because the clinical details differ substantially. Citation: Lan Dong, Jinhua Tian, Songming He, Chuchao Zhu, Jian Wang, Chen Liu, Jing Yang. Possible Vertical Transmission of SARS-CoV-2 From an Infected Mother to Her Newborn. JAMA. Published online March 26, 2020. doi:10.1001/jama.2020.4621

Study 11. Caesarean birth & neonatal infection, China

Case report (click here) of a baby born by Caesarean to an infected mother at Wuhan Tongji Hospital.  The baby was separated from the mother at birth but became infected (pharyngeal PCR at 36 hours). Both mother and baby recovered. I believe this case report is additional to the 33 Wuhan neonatal cases reported in JAMA, because the details (e.g. birth weight) do not align. This is therefore the fourth infected baby born by Caesarean. Citation: Shaoshuai Wang, Lili Guo, Ling Chen, Weiyong Liu, Yong Cao, Jingyi Zhang, Ling Feng A Case Report of Neonatal 2019 Coronavirus Disease in China. Clinical Infectious Diseases, ciaa225, https://doi.org/10.1093/cid/ciaa225

Study 10. Two cases from Renmin Hospital, Wuhan, China

Two pregnant doctors with Covid-19 both delivered by Caesarean at term (click here). Also remnin two cases.  Babies separated and not infected. Probably additional to the 33 JAMA Wuhan neonates because neither neonate was transferred to Wuhan Children’s Hospital. Citation: Cuifang Fan, Di Lei, Congcong Fang, Chunyan Li, Ming Wang, Yuling Liu, Yan Bao, Yanmei Sun, Jinfa Huang, Yuping Guo, Ying Yu, Suqing Wang Perinatal Transmission of COVID-19 Associated SARS-CoV-2: Should We Worry?  Clinical Infectious Diseases, ciaa226, https://doi.org/10.1093/cid/ciaa226

28 March 2020 update. Three more more primary scientific reports.

Study 9. A Caesarean birth from China

This case report is in Chinese but has an English abstract. Click here. It’s from the First Affiliated Hospital, College of Medicine, Zhejiang University School of Medicine, Hangzhou. There appears to be no overlap of the authors with the Zhejiang Caesarean below, so this may be a new case. The Caesarean is reported as being “successful” which presumably means both mother and baby survived. Citation: Kang X, Zhang R, He H, Yao Y, Zheng Y, Wen X, Zhu S. Anesthesia management in cesarean section for a patient with coronavirus disease 2019. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2020 May 25;49(1):0. Chinese. PMID: 32207592   

12 June reconsideration. The hospitals in S9 & S4 are both First Affiliated Hospital Zhejiang University grid.452661.2.  The full Chinese text of S9 seems to be no longer available so not possible to compare clinical details. Assume this is same case as that in S4.

Study 8. The 33 neonatal cases from China

A series of 33 neonates born to mothers who had Covid-19. All from Wuhan Children’s Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan. Reported in JAMA here. It seems possible that some or all of these infants are also included in the other Union Hospital Tongji series below.  Of the 26 neonates delivered by Caesarean three became infected. One born at 30 weeks and 2 days developed RDS, pneumonia and suspected sepsis, and required non-invasive ventilation. The authors speculate that some of his problems were related to prematurity rather than COVID-19. The other two neonates were healthy. All three survived. By inference, although this is not specifically stated in the paper, none of the seven infant born vaginally became infected.  Citation: Lingkong Zeng, Shiwen Xia, Wenhao Yuan, Kai Yan, Feifan Xiao, Jianbo Shao, Wenhao Zhou, Neonatal Early-Onset Infection With SARS-CoV-2 in 33 Neonates Born to Mothers With COVID-19 in Wuhan, China. JAMA Pediatr. Published online March 26, 2020. doi:10.1001/jamapediatrics.2020.0878

Study 7. The Quingdao case, China

This appears to be the first pregnancy case from  that city. Click here. The mother developed Covid-19 at 30 weeks but recovered and was discharged. At the time the report was written the pregnancy was ongoing. Citation: Rong Wen, Yue Sun, Quan-Sheng Xing A patient with SARS-CoV-2 infection during pregnancy in Qingdao, China Journal of Microbiology, Immunology and Infection Available online 10 March 2020 https://doi.org/10.1016/j.jmii.2020.03.004

22 March 2020 estimate. Assuming all the Union Hospital Tongji cases overlap, i.e. that Tongji has reported only 15 in total, there have been 38 published cases (39 babies) of Covid-19 infection in pregnancy. There have been no reports in the scientific literature of any maternal deaths, and all neonates have survived and not been infected. Four neonates remain undelivered.

Note 22 March 2020.  David A Schwarz (click here) in a review in Arch Pathol (preprint available March 21st) also makes the total 38 published cases.  However he includes a series published only in Chinese (his reference 17) Zhang I, Jiang Y, Wei M, Cheng BH, Zhou XC, Li J, et al. 湖北地区新型冠状病毒肺炎流行期间孕妇的 384 妊娠结局分析 [Analysis of the Pregnancy Outcomes in Pregnant Women With COVID-19 in Hubei Province]. Zhonghua Fu Chan Ke Za Zhi . 2020;55(0), E009. Available from: http://rs.yiigle.com/yufabiao/1184338.htm (accessed and translated 12 March 2020).  He reports this as including 16 cases.  For the moment I’ve not included this Hubei series, (but see Study 6a added 1 April).

Study 6a. 16 cases from Remnin, China

The cases included by David Schwarz on March 21 (see note above). English abstract (click here). Full text in Chinese here. Google translate used. The authors come from Remnin Hospital, but the paper reports that all 16 women were delivered by Caesarean at the Eastern Hospital of Wuhan University People’s Hospital.  Therefore assume no duplicates. Citation: Zhang Lu, Jiang Yan, Wei Min, et al. Analysis of pregnancy outcomes of pregnant women during the epidemic of new coronavirus pneumonia in Hubei [J / OL]. Chinese Journal of Obstetrics and Gynecology, 2020,55 (2020-03-08). http://rs.yiigle.com/yufabiao/1184338.htm. DOI: 10.3760 / cma.j.cn112141-20200218-00111. 

Study 6. The 15 Union hospital Tongji cases, China

A series of 15 pregnant women, of whom 11 had delivered and four remained undelivered from Union Hospital, Tongji Medical College, click here. These may include the four from the same hospital below and also possibly the 9 cases from the same hospital in Translational Paediatrics. Citation: Dehan Liu, Lin Li, Xin Wu, Dandan Zheng, Jiazheng Wang, Lian Yang and Chuansheng Zheng. Pregnancy and Perinatal Outcomes of Women With Coronavirus Disease (COVID-19) Pneumonia: A Preliminary Analysis American Journal of Roentgenology: 1-6. 10.2214/AJR.20.23072

Study 5. 9 cases from China

Published in Translational Paediatrics (click here). Nine mothers, ten neonates from Union Hospital Tongji, Wuhan. Citation: Huaping Zhu, Lin Wang, Chengzhi Fang, Sicong Peng, Lianhong Zhang, Guiping Chang, Shiwen Xia, Wenhao Zhou. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Translational Pediatrics Vol 9, No 1 (February 2020)  

Study 4. Case from China

From the First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China (click here) Caesarean for unclear indication. Baby not infected. Citation: Yang Li, Ruihong Zhao, Shufa Zheng, Xu Chen, Jinxi Wang, Xiaoli Sheng, Jianying Zhou, Hongliu Cai, Qiang Fang, Fei Yu, Jian Fan, Kaijin Xu, Yu Chen and Jifang Sheng Lack of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, China. Emerging Infectious Diseases. 2020 Apr [date cited]. https://doi.org/10.3201/eid2606.200287 DOI: 10.3201/eid2606.200287

Study 3. The Sun Yat Sen series from China (withdrawn)

These 13 cases were reported from the First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Province. Guangdong. (click here). Also pre-publication text 10.1016@j.jinf.2020.02.028). They included 3 patients from Zhejiang, 3 from other cities of Hubei and 1 each from Fujian, Shanxi, Beijing, Guangdong, Jiangxi, Heilongjiang and Anhui.   No infected neonates but one mother seriously ill on ECMO.  16 April update. Since patients in this series came from multiple centres, both in and outside Hubei province, they are likely to overlap with other studies. 12 mothers (3 undelivered) and 9 babies have therefore been removed from the running total. However case 6, where the woman was reported to be on ECMO and the baby stillborn, does not appear to have been reported elsewhere, so remains in the running totals. Citation: Yangli Liu, Haihong Chen, Kejing Tang, Yubiao Guo. Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy J Infect. https://doi.org/10.1016/j.jinf.2020.02.028 (Keywords; clinical features, therapy, ECMO).  1 February update. This article has been withdrawn (click here for details). No reasons given.

Study 2. The first Union Hospital Tongji series

Study 2a From Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan. The original abstract here, described three cases and linked to an original paper in Chinese. Citations: Chen S, Huang B, Luo DJ, Li X, Yang F, Zhao Y, Nie X, Huang BX. Pregnant women with new coronavirus infection: a clinical characteristics and placental pathological analysis of three cases. (click here)  Zhonghua Bing Li Xue Za Zhi. 2020 Mar 1;49(0):E005. doi: 10.3760/cma.j.cn112151-20200225-00138 (click here).

Study 2b. A pre-print of three cases from Tongji (Click here or preprints202002.0373.v1) which includes some authors from the Liverpool School of Tropical Medicine & Hygiene. Again these may overlap, or even be the same cases. Citation: Liu, W.; Wang, Q.; Zhang, Q.; Chen, L.; Chen, J.; Zhang, B.; Lu, Y.; Wang, S.; Xia, L.; Huang, L.; Wang, K.; Liang, L.; Zhang, Y.; Turtle, L.; Lissauer, D.; Lan, K.; Feng, L.; Yu, H.; Liu, Y.; Sun, Z. Coronavirus Disease 2019 (COVID-19) During Pregnancy: A Case Series. Preprints 2020, 2020020373

Study 2c. Four cases later published in Frontiers (click here). These are also from Tongji and may may overlap with studies 2a & 2b Yan Chen, Hua Peng, Lin Wang, Yin Zhao, Lingkong Zeng, Hui Gao and Yalan Liu.  Infants Born to Mothers With a New Coronavirus (COVID-19)  Front. Pediatr., 16 March 2020 | https://doi.org/10.3389/fped.2020.00104 or fped-08-00104

Study 1. The original Lancet nine, China

All from Zhongnan Hospital of Wuhan University, Wuhan, click here or 1-s2.0-S0140673620303603-main (2)).  Citation: Huijun Chen, Juanjuan Guo, Chen Wang, Fan Luo, Xuechen Yu, Wei Zhang, Jiafu Li, Dongchi Zhao, Dan Xu, Qing Gong, Jing Liao, Huixia Yang, Wei Hou, Yuanzhen Zhang. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. Volume 395, Issue 10226, 7–13 March 2020, Pages 809-815. (Keywords; clinical features, therapy) [important]

Jim Thornton, Keelin O’Donoghue & Kate Walker